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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_GUM_EXALLC for full statistics.

Malignant neoplasm of gum

C3_GUM

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C03
  • Cause of death: ICD-9 143
  • Cause of death: ICD-8 143
  • Cancer registry: Topography ICD-O-3 C03
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

136

4. Check minimum number of events

None

136

5. Include endpoints

None

136

6. Filter based on genotype QC (FinnGen only)

136

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
5
First used in FinnGen datafreeze
DF9

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 136 62 74
Unadjusted period prevalence (%) 0.03 0.02 0.03
Median age at first event (years) 70.05 72.74 67.80

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
124
Matched controls
1240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C03.1
ICD-10 Finland
Malignant neoplasm: Lower gum
+∞
113.7
91
*
8070/3-C03.1
ICD-O-3
Squamous cell carcinoma, NOS, of lower gum
+∞
76.1
65
*
EDB00
NOMESCO Finland
Partial excision of mandible
+∞
74.7
64
*
ECA20
NOMESCO Finland
Biopsy of gingiva
358.1
72.8
67
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
427.0
54.8
51
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
101.2
50.4
53
9
C03.0
ICD-10 Finland
Malignant neoplasm: Upper gum
686.3
48.9
45
*
130
Kela drug reimbursment
Malignant tumour
26.2
47.7
72
62
GBB00
NOMESCO Finland
Tracheostomy
91.7
46.8
50
9
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
617.1
45.3
42
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
21.1
45.3
76
86
SAA03
NOMESCO Finland
Extended examination of mouth
22.2
44.2
109
305
JDB10
NOMESCO Finland
Percutaneous gastrostomy
63.1
44.0
50
13
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
82.9
43.3
47
9
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
17.0
40.9
103
277
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
+∞
37.4
34
*
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
31.3
33.7
45
22
WF003
NOMESCO Finland
Adjuvant radiotherapy
38.6
31.8
40
15
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
36.2
31.3
40
16
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
88.8
30.7
33
5
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
22.8
30.4
45
30
EKA10
NOMESCO Finland
Biopsy of cheek
43.1
30.3
37
12
EBB10
NOMESCO Finland
Insertion of dental implant
66.1
30.3
34
7
8070/3-C03.0
ICD-O-3
Squamous cell carcinoma, NOS, of upper Gum
+∞
29.3
27
*
SBB10
NOMESCO Finland
Teeth copy
18.4
28.0
45
37
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
10.0
27.2
65
123
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
19.2
26.2
41
31
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
89.4
26.0
28
*
ZZQ20
NOMESCO Finland
Free microvascular graft of skin, muscle and bone
+∞
25.9
24
*
EBB15
NOMESCO Finland
Insertion of dental implant abutment
162.8
25.7
26
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
29.4
24.6
33
15
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
16.2
23.4
39
34
WX110
NOMESCO Finland
Local anesthesy
12.1
22.5
114
601
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
42.5
22.2
27
8
EBA15
NOMESCO Finland
Extraction of large number of teeth
19.1
21.4
33
23
WX408
NOMESCO Finland
General anesthesy, balanced
6.5
20.7
76
244
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
88.1
20.4
22
*
A07AA02
ATC
nystatin; oral
12.6
20.3
38
42
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
6.2
19.6
90
371
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
+∞
19.3
18
*
EEB00
NOMESCO Finland
Partial excision of maxilla
222.2
19.1
19
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
12.7
19.0
35
37
EP1AE
NOMESCO Finland
Neck ultrasound examination
13.3
19.0
34
34
SAA04
NOMESCO Finland
Special inverstigation of mouth
15.0
18.9
32
28
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
62.5
18.6
21
*
ZXE90
NOMESCO Finland
More than 22 hours
104.4
17.0
18
*
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
104.4
17.0
18
*
A03FA01
ATC
metoclopramide; systemic, rectal
5.9
16.9
57
155
K13.78
ICD-10 Finland
Other change in the oral mucosa
25.3
16.7
23
11
K13.29
ICD-10 Finland
Indefinite leukoplakia
55.5
16.5
19
*
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
13.2
16.3
29
28
SBA00
NOMESCO Finland
Microbiological examinations
26.4
16.2
22
10
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
31.2
16.2
21
8
SPA20
NOMESCO Finland
Selection and insertion of implantdistans
97.7
16.0
17
*
ZXE60
NOMESCO Finland
More than 12 and less than 15 hours
182.0
15.9
16
*
EHA10
NOMESCO Finland
Biopsy of palate
52.1
15.5
18
*
XF612
NOMESCO Finland
Measurement of central venous pressure
+∞
14.9
14
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
18.8
14.6
22
14
SXC03
NOMESCO Finland
Other oral or dental procedure
34.7
14.3
18
6
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
60.7
14.2
16
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
11.9
14.1
26
27
R4190
NOMESCO Finland
Nutritional therapy
16.4
13.9
22
16
C03.9
ICD-10 Finland
Malignant neoplasm: Gum, unspecified
+∞
13.8
13
*
EEB10
NOMESCO Finland
Maxillectomy
+∞
13.8
13
*
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
56.4
13.2
15
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
56.4
13.2
15
*
N02AA05
ATC
oxycodone; systemic
5.0
12.7
47
134
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
+∞
12.7
12
*
EDB20
NOMESCO Finland
Hemimandibulectomy
+∞
12.7
12
*
WX872
NOMESCO Finland
Intensive care
9.0
12.6
27
37
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
42.2
12.5
15
*
L43.8
ICD-10 Finland
Other lichen planus
42.2
12.5
15
*
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
52.1
12.2
14
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
17.3
11.7
18
12
C06.9
ICD-10 Finland
Malignant neoplasm: Mouth, unspecified
+∞
11.6
11
*
EDC42
NOMESCO Finland
Mandibular repair with implant
+∞
11.6
11
*
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
10.9
11.6
22
24
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
9.3
11.6
24
31
SPF20
NOMESCO Finland
Temporary soling for filling
28.1
11.4
15
6
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
28.1
11.4
15
6
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
7.7
11.1
26
41
WZC30
NOMESCO Finland
Teaching
5.3
11.0
36
88
K13.20
ICD-10 Finland
Idiopathic leukoplakia
65.8
10.8
12
*
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
65.8
10.8
12
*
TEA00
NOMESCO Finland
Biopsy of lip
65.8
10.8
12
*
XX3DW
NOMESCO Finland
Time consuming IT work
5.7
10.6
32
71
RS316
NOMESCO Finland
NA
119.7
10.6
11
*
C06.0
ICD-10 Finland
Malignant neoplasm: Cheek mucosa
+∞
10.6
10
*
SAA01
NOMESCO Finland
Simple examination of mouth
4.0
10.3
99
615
K05.31
ICD-10 Finland
Periodontitis pronounced
5.9
10.3
30
64
Z2446
NOMESCO Finland
Social worker
7.2
10.2
25
42
R4110
NOMESCO Finland
Physiotherapy
3.6
10.1
60
255
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.5
10.0
81
434
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
7.4
10.0
24
39
ECA35
NOMESCO Finland
Complicated excision of lesion of gingiva
59.8
9.8
11
*
ZZA00
NOMESCO Finland
Split skin graft
10.0
9.7
19
22
SXA10
NOMESCO Finland
Epithel biopsy of mouth
19.5
9.7
14
8
SPF00
NOMESCO Finland
Repatation of teeth prosthesis
12.1
9.6
17
16
EB1WA
NOMESCO Finland
NA
107.9
9.6
10
*
EJB10
NOMESCO Finland
Excision of lesion of apex or body of tongue
+∞
9.5
9
*
K05.30
ICD-10 Finland
Periodontitis complex
4.7
9.3
34
93
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
9.1
9.3
19
24
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
39.9
9.2
11
*
EBA00
NOMESCO Finland
Extraction of tooth
3.4
9.1
58
255
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.8
8.9
45
163
ZX090
NOMESCO Finland
Other technic of radiotherapy
11.3
8.8
16
16
EJB30
NOMESCO Finland
Excision of lesion of floor of mouth
53.9
8.8
10
*
WF002
NOMESCO Finland
Radical radiotherapy
8.1
8.7
19
27
EKB00
NOMESCO Finland
Excision of lesion of cheek
29.9
8.6
11
*
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
3.3
8.6
58
262
C06.21
ICD-10 Finland
Malignant tumor of the lower retromolar surface
+∞
8.4
8
*
C06.29
ICD-10 Finland
Malignant tumor of the retromolar surface UNS
+∞
8.4
8
*
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
+∞
8.4
8
*
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
+∞
8.4
8
*
ECA30
NOMESCO Finland
Excision of lesion of gingiva
18.8
8.3
12
7
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
5.9
8.3
23
46
ECB20
NOMESCO Finland
Oral alveoplasty
35.9
8.2
10
*
WX402
NOMESCO Finland
General anaesthesia
4.0
8.0
34
106
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
10.5
8.0
15
16
WZB00
NOMESCO Finland
Telephone receipt or other advice
3.3
7.9
48
199
PH2CD
NOMESCO Finland
Very extensive CT of inferior vena cava, pelvic veins and veins of lower extremity
48.1
7.8
9
*
SPA48
NOMESCO Finland
Precision impression for denture, demanding
48.1
7.8
9
*
GD1AD
NOMESCO Finland
Thorax CT examination
8.0
7.8
17
24
SPF30
NOMESCO Finland
Soling for prothesis
13.0
7.8
13
11
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
5.7
7.8
22
45
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
26.9
7.7
10
*
R13
ICD-10 Finland
Dysphagia
5.9
7.7
21
41
SAA02
NOMESCO Finland
Basic examination of mouth
3.0
7.7
85
522
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
6.2
7.6
20
37
WX730
NOMESCO Finland
Conventional respirator
14.6
7.6
12
9
K13.28
ICD-10 Finland
Other leukoplakia or disorder of epithelium of the palate or tongue
85.0
7.5
8
*
SPA05
NOMESCO Finland
Guiding rail
85.0
7.5
8
*
K12.2
ICD-10 Finland
Cellulitis and abscess of mouth
85.0
7.5
8
*
Z51.5
ICD-10 Finland
Palliative care
5.7
7.4
21
43
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.8
7.4
73
415
A04AD12
ATC
aprepitant; systemic
17.1
7.4
11
7
8070/3-C03.9
ICD-O-3
Squamous cell carcinoma, NOS, of gum, NOS
+∞
7.4
7
*
EKC20
NOMESCO Finland
Plastic repair of cheek
+∞
7.4
7
*
EDW99
NOMESCO Finland
Other operation on mandible
+∞
7.4
7
*
SPA52
NOMESCO Finland
Determination of bite and dental arch location, very demanding
+∞
7.4
7
*
ZZQ40
NOMESCO Finland
Free microvascular graft of bone
+∞
7.4
7
*
SPA02
NOMESCO Finland
Preparation for dental prosthetics
9.7
7.3
14
16
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
21.6
7.3
10
5
L43.9
ICD-10 Finland
Lichen planus, unspecified
32.1
7.3
9
*
EBA10
NOMESCO Finland
Surgical removal of tooth
4.8
7.2
24
59
TPH07
NOMESCO Finland
Cathetrisation of artery
4.0
7.2
30
92
H02AB02
ATC
dexamethasone; systemic
4.2
7.0
27
77
WX707
NOMESCO Finland
Fiberoscopic intubation
42.4
6.8
8
*
SPF11
NOMESCO Finland
Fitting of dental prosthesis
24.0
6.8
9
*
B37.08
ICD-10 Finland
Other candidal stomatitis
24.0
6.8
9
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
9.5
6.7
13
15
Z3226
NOMESCO Finland
Physiotherapist
3.1
6.6
40
164
ZXE20
NOMESCO Finland
More than three and less than five hours
3.4
6.6
33
118
C04.0
ICD-10 Finland
Malignant neoplasm: Anterior floor of mouth
73.5
6.5
7
*
EDA10
NOMESCO Finland
Biopsy of mandible
73.5
6.5
7
*
QAE30
NOMESCO Finland
Excision and repair of surgical scar in head or neck
73.5
6.5
7
*
SPF10
NOMESCO Finland
Demanding repatation of teeth prosthesis
10.1
6.4
12
13
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
7.7
6.4
14
20
ZX095
NOMESCO Finland
Combined chemoradiotherapy
19.2
6.4
9
5
RS240
NOMESCO Finland
NA
+∞
6.3
6
*
K13.22
ICD-10 Finland
Erythroplakia of oral epithelium, including tongue
+∞
6.3
6
*
K08.0
ICD-10 Finland
Exfoliation of teeth due to systemic causes
+∞
6.3
6
*
EEA10
NOMESCO Finland
Biopsy of maxilla
+∞
6.3
6
*
EEW99
NOMESCO Finland
Other operation on maxilla
+∞
6.3
6
*
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
9.4
6.2
12
14
A04AA55
ATC
palonosetron, combinations; systemic
9.4
6.2
12
14
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.2
6.1
18
39
A04AA01
ATC
ondansetron; systemic, rectal
4.9
6.1
19
44

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_GUM – Malignant neoplasm of gum

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).