Polyp of middle ear

H8_POLYPMIDD

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H74.4 Cause of death: ICD-10 — H74.4 2 out of 7 registries used, show all original rules.	58
4. Check minimum number of events None	58
5. Include endpoints None	58
6. Filter based on genotype QC (FinnGen only)	53

Control definitions (FinnGen only)

Control exclude: H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: H74
Name in latin: Polypus auris mediae

NAME	H8_POLYPMIDD
CONTROL_EXCLUDE	H8_MIDDLEMASTOID
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H744
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H744
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Polyp of middle ear based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	794	336	456
Only index persons	694	295	399
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.02
Median age at first event (years)
Whole population	11.75	10.66	12.26
Only index persons	13.86	11.53	15.58

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	53	29	24
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	48.77	45.31	52.96

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
58: Matched controls
580

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

H74.4

ICD-10 Finland

Polyp of middle ear

+∞

83.1

H65.3

ICD-10 Finland

Chronic mucoid otitis media

+∞

24.7

DCA20

NOMESCO Finland

Insertion of ventilating tube through tympanic membrane

+∞

21.1

H72.0

ICD-10 Finland

Central perforation of tympanic membrane

+∞

17.6

H65.2

ICD-10 Finland

Chronic serous otitis media

+∞

14.1

H71

ICD-10 Finland

Cholesteatoma of middle ear

+∞

14.1

UDC00

NOMESCO Finland

Ear microscopy

16.5

13.9

H60.9

ICD-10 Finland

Otitis externa, unspecified

19.5

10.8

Z01.1

ICD-10 Finland

Examination of ears and hearing

6.7

10.7

EMB30

NOMESCO Finland

Adenotomy

118.6

9.7

H66.9

ICD-10 Finland

Otitis media, unspecified

10.0

8.4

J01EE02

ATC

sulfadiazine and trimethoprim; systemic

4.9

8.2

H65.1

ICD-10 Finland

Other acute nonsuppurative otitis media

+∞

7.4

J35.2

ICD-10 Finland

Hypertrophy of adenoids

45.5

6.9

H90.6

ICD-10 Finland

Mixed conductive and sensorineural hearing loss, bilateral

78.1

6.6

H60.3

ICD-10 Finland

Other infective otitis externa

30.3

6.4

H74.1

ICD-10 Finland

Adhesive middle ear disease

+∞

6.4

H70.1

ICD-10 Finland

Chronic mastoiditis

+∞

6.4

DC1AD

NOMESCO Finland

Temporalbone CT

+∞

6.4

H66.3

ICD-10 Finland

Other chronic suppurative otitis media

+∞

6.4

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3000494) Fungus identified in Specimen by Culture

3.23

3.16

1.6

1.3

—

(3019225) pH of Specimen

3.95

2.85

3.0

7.0

—

(3009343) pH of Capillary blood

3.26

2.85

2.8

6.7

—

7.45

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

3.33

2.75

2.8

6.8

0.16

1.81

mmol/l

—

(3022313) Gas panel - Capillary blood

3.68

2.67

3.0

7.9

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

5.01

2.33

1.3

2.0

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

2.83

2.28

5.9

4.4

37.00

33.29

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.78

2.07

3.7

1.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

3.27

2.02

3.3

1.6

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

4.86

1.98

1.2

2.1

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

3.81

1.89

4.0

1.3

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

3.03

1.87

2.5

2.2

96.75

127.08

ng/l

—

(3020630) Protein [Mass/volume] in Serum or Plasma

2.69

1.56

3.1

1.8

64.37

66.63

g/l

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.56

1.28

1.2

1.4

—

(3044640) Blood type and Crossmatch panel - Blood

130

1.82

1.25

3.3

2.8

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.90

1.23

3.5

2.7

—

(3013512) EKG study

114

1.84

1.21

5.5

3.7

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.00

1.20

0.0

3.2

—

(40761536) Microorganisms panel - Urine sediment

0.00

1.18

0.0

4.4

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.00

1.01

0.0

1.1

—

(3025941) Bacteria identified in Stool by Culture

0.00

1.00

0.0

1.2

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

0.00

0.99

0.0

2.4

—

(1761868) Lipid panel - Serum or Plasma

159

0.55

0.89

2.3

2.7

—

(21494755) Public health laboratory ask at order entry panel

1.86

0.87

1.6

1.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.82

0.86

3.6

2.2

—

(3002256) Pathology report gross observation

1.80

0.73

1.1

1.2

—

(3003694) ABO and Rh group [Type] in Blood

123

0.59

0.63

1.3

1.4

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.68

0.63

1.5

1.9

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

0.61

0.0

1.6

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.00

0.61

0.0

2.5

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

402

1.53

0.61

4.7

3.8

1.28

1.25

mmol/l

0.16

362

(3041096) Erythrocytes [Presence] in Urine by Automated

131

0.63

0.61

1.9

3.7

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.85

0.61

3.3

1.6

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

279

1.42

0.59

7.7

9.3

4.14

4.09

e9/l

0.05

246

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

414

1.54

0.59

13.5

12.1

82.00

83.80

ml/min/173m2

0.18

331

(3042936) Bacteria identified in Isolate by Culture

1.62

0.58

2.0

1.6

—

(40761511) CBC panel - Blood by Automated count

506

0.62

0.58

14.9

12.1

—

(3026782) Osmolality of Urine

0.57

0.58

2.3

3.1

487.50

547.78

mosm/kgh2o

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.56

0.57

3.1

2.1

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.64

0.56

3.5

1.8

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

416

1.51

0.55

5.2

4.2

1.50

1.45

mmol/l

0.40

375

(3020682) Albumin/Creatinine [Ratio] in Urine

130

1.44

0.52

4.5

3.2

54.93

6.93

mg/mmol

—

(3012516) Albumin [Mass/volume] in Urine

121

1.45

0.51

3.9

2.8

138.82

561.21

mg/l

—

(3023368) Bacteria identified in Blood by Culture

112

1.46

0.51

4.1

4.2

—

(40760892) CBC W Ordered Manual Differential panel - Blood

226

1.36

0.49

4.0

6.8

—

(3000850) Epithelial cells [#/volume] in Urine

101

0.65

0.44

2.1

2.4

7.03

5.83

e6/l

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.61

0.43

2.4

1.6

1.07

g/l

—

(4200892) Spirometry reversibility

1.56

0.42

1.4

1.6

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.56

0.42

1.0

1.3

—

(40768804) Tissue Pathology biopsy report

163

1.35

0.42

2.0

1.8

—

(3045414) Leukocytes [Presence] in Urine

0.00

0.42

0.0

1.6

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.42

0.0

1.3

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.42

0.0

1.0

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.42

0.0

6.1

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.42

0.0

1.4

—

320.80

—

(3037467) Urinalysis macro (dipstick) panel - Urine

310

1.33

0.41

2.9

4.4

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.40

0.0

1.2

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.40

0.0

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.40

0.0

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.40

0.0

1.2

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

186

0.74

0.39

2.4

4.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.45

0.37

1.5

1.8

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

418

1.34

0.34

5.0

4.3

4.72

4.59

mmol/l

0.35

381

(3031040) Bacteria [#/volume] in Urine by Automated count

285

1.27

0.34

3.1

4.3

—

53.20

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

430

1.34

0.32

5.5

4.8

2.65

2.72

mmol/l

0.22

392

(3015736) pH of Urine

190

0.78

0.29

2.4

3.4

—

5.92

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

0.68

0.28

2.4

2.5

26.60

28.79

—

(3035350) Ketones [Presence] in Urine by Test strip

230

0.80

0.28

2.5

4.0

—

0.00

—

(36304419) Bacteria [Presence] in Urine

126

0.75

0.28

2.8

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

106

1.29

0.26

2.5

3.8

—

(3018095) Leukocytes [#/volume] in Urine

166

0.79

0.25

3.6

3.3

51.01

49.16

e6/l

—

120

(3026008) Bacteria identified in Urine by Culture

124

0.77

0.24

1.2

3.5

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

145

0.78

0.24

2.5

3.4

30.58

29.89

u/l

0.05

137

(3028626) Oxygen [Partial pressure] in Capillary blood

1.38

0.24

3.0

6.6

8.44

9.11

kpa

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.38

0.24

2.2

2.0

8.62

9.59

g/l

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

107

1.28

0.24

1.7

1.5

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

123

0.77

0.23

1.2

1.4

—

0.73

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.29

0.23

1.7

—

(3021601) Nitrite [Presence] in Urine by Test strip

226

0.82

0.22

4.5

5.5

—

0.00

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

1.21

0.22

4.0

4.4

19.06

11.91

ug/l

—

(3002582) Erythrocytes [#/volume] in Urine

143

0.80

0.22

2.7

25.91

23.23

e6/l

—

113

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.3

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.21

0.0

2.0

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.6

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.21

0.0

1.2

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.21

0.0

1.2

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.21

0.0

1.8

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.31

0.21

1.5

—

(36660697) Celiac disease serology panel - Serum

1.31

0.21

1.3

1.1

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.2

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.20

0.0

1.2

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.20

0.0

1.4

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

1.6

—

41.36

—

(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum

0.00

0.20

0.0

1.4

—

129.60

—

(3018418) pH of Serum or Plasma

121

0.79

0.20

4.3

3.4

—

7.40

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.23

0.19

1.0

1.3

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

439

1.23

0.19

5.1

4.4

2.26

1.90

mu/l

0.94

395

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.21

0.19

3.3

9.0

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.18

0.17

1.1

1.4

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

400

1.18

0.16

6.9

5.5

43.64

40.37

mmol/mol

0.59

373

(3009261) Glucose [Presence] in Urine by Test strip

230

0.86

0.15

2.6

4.1

—

0.00

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

484

1.24

0.15

13.8

13.5

19.91

24.09

mg/l

0.42

374

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

330

1.15

0.15

2.8

3.2

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

166

1.12

0.09

5.2

4.0

21.49

40.96

ng/l

0.53

120

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

117

1.14

0.09

5.2

4.1

14.07

22.50

—

(3012544) pH of Venous blood

1.04

0.09

2.8

4.4

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.04

0.09

1.5

1.3

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

1.05

0.08

1.1

1.2

—

39.04

—

(3022217) INR in Platelet poor plasma by Coagulation assay

203

0.90

0.07

22.1

10.9

1.45

1.26

inr

—

(3044889) 12 lead EKG panel

300

0.93

0.04

2.8

3.9

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

189

0.93

0.03

2.3

5.3

31.46

35.47

g/l

1.16

181

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

1.09

0.02

1.4

1.8

453.40

481.50

pmol/l

—

(40758558) Short blood count panel - Blood

123

1.07

0.02

4.1

5.4

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

427

0.94

0.01

4.9

4.5

6.05

5.91

mmol/l

0.24

387

(3019150) Specific gravity of Urine by Refractometry

114

1.07

0.01

2.3

3.4

1.01

kg/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

156

0.95

0.00

2.5

3.0

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

151

0.99

0.00

1.6

3.1

2.35

2.36

mmol/l

—

133

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

239

1.01

0.00

5.5

6.2

9.29

15.43

umol/l

2.02

224

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

343

0.98

0.00

4.8

3.8

14.55

14.89

pmol/l

0.28

313

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

156

1.04

0.00

2.5

1.8

89.30

94.20

pmol/l

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

198

1.02

0.00

3.9

3.0

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.0

1.7

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.8

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.2

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

17.11

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

0.0

1.5

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.0

1.3

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.2

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3011897) Casein IgE Ab [Units/volume] in Serum

0.00

0.0

1.3

—

0.57

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.0

1.3

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.0

1.5

—

(3024928) Oxygen saturation in Venous blood

0.00

0.0

8.7

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.0

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.0

1.7

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

1.8

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.5

—

254.00

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

0.0

1.3

—

(3012494) Peanut IgE Ab [Units/volume] in Serum

0.00

0.0

1.3

—

0.25

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

0.00

-0.00

0.0

1.7

—

62.71

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

-0.00

0.0

1.3

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

-0.00

0.0

1.4

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

0.00

-0.00

0.0

1.7

—

4.96

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

1.2

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3023410) Appearance of Cerebral spinal fluid

0.00

-0.00

0.0

2.3

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

-0.00

0.0

1.3

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

-0.00

0.0

1.0

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

1.6

—

90.18

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

-0.00

0.0

2.4

—

5.15

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

88.60

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

5.9

—

1.26

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.0

—

(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.8

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.2

—

188.92

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(3008401) Mugwort IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

0.41

—

(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.0

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.0

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.1

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

2.6

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3000991) Gas panel - Venous blood

0.98

-0.00

7.0

8.5

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3010421) pH of Blood

0.00

-0.00

0.0

2.4

—

7.42

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

4.4

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

-0.00

0.0

1.0

—

(3010726) Horse dander IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

0.17

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

-0.00

0.0

1.6

—

9.10

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

-0.00

0.0

1.4

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

3.8

—

290.94

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(3044927) Protein electrophoresis panel - Urine

0.00

-0.00

0.0

1.2

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.3

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

-0.00

0.0

1.2

—

37.44

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.2

—

6.56

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(3000012) Reticulocyte production index

0.00

-0.00

0.0

1.0

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(3027456) Digoxin [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

4.1

—

0.86

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

5.0

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

6.6

—

3.24

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

-0.00

0.0

2.4

—

8.89

—

(3027901) Hemoglobin [Mass/volume] in Arterial cord blood

0.00

-0.00

0.0

1.0

—

178.20

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

-0.00

0.0

1.4

—

(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3003888) Timothy IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

9.79

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.4

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint H8_POLYPMIDD and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H8_POLYPMIDD.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: H8_POLYPMIDD – Polyp of middle ear

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Polyp of middle ear

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints