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Melanoma in situ of other and unspecified parts of face

CD2_INSITU_MELANOMA_FACE

melanoma: A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

414

4. Check minimum number of events

None

414

5. Include endpoints

None

414

6. Filter based on genotype QC (FinnGen only)

402

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 402 210 192
Unadjusted period prevalence (%) 0.08 0.07 0.09
Median age at first event (years) 73.00 71.86 74.24

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
414
Matched controls
4140
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
+∞
307.7
402
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
47.4
307.7
325
296
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
10.6
122.7
182
285
ZZR00
NOMESCO Finland
Flap of skin
21.7
118.9
95
56
L57.0
ICD-10 Finland
Actinic keratosis
8.1
98.2
193
404
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
42.6
80.3
49
13
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
8.9
79.7
118
177
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
22.2
79.5
61
32
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
157.1
74.8
77
6
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
13.1
66.5
68
61
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
11.7
60.0
66
66
R23.8
ICD-10 Finland
Other and unspecified skin changes
5.2
59.1
185
558
TQW99
NOMESCO Finland
Other minor procedure on skin
7.8
57.7
91
144
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
6.0
52.7
113
243
D03.30
ICD-10 Finland
Melanoma in situ on the lip
+∞
42.4
40
*
S18
ICPC
Laceration/cut
4.2
40.1
301
1596
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
5.8
38.9
81
167
C43.31
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face originating in lentigo maligna
143.1
37.4
39
*
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
6.9
34.6
58
96
ZXC50
NOMESCO Finland
Cryotherapy
6.8
31.0
52
86
D06BB10
ATC
imiquimod; topical
5.7
31.0
63
126
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
6.7
30.1
51
85
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
9.0
29.6
38
46
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
7.8
27.6
40
56
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
6.4
27.3
48
83
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
99.9
26.0
28
*
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
6.7
25.9
43
70
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
4.3
24.3
71
191
L82
ICD-10 Finland
Seborrhoeic keratosis
3.0
22.6
130
541
SPAT1153
SPAT
Removal of sutures
2.7
22.2
208
1118
ZXC20
NOMESCO Finland
Use of chemical agents
6.6
21.0
35
57
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
6.5
18.9
32
53
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
5.9
18.7
35
64
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
7.3
18.5
28
41
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
4.9
18.4
43
96
ZZA00
NOMESCO Finland
Split skin graft
5.6
17.8
35
67
WX110
NOMESCO Finland
Infiltration anesthesia
2.7
17.5
310
2169
ZZA50
NOMESCO Finland
Full thickness skin graft
18.4
17.2
26
15
DHB00
NOMESCO Finland
Excision of lesion of external nose
15.1
16.6
27
19
S82
ICPC
Naevus/mole
2.8
14.7
83
335
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
5.8
14.5
27
49
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
16.5
14.1
22
14
8720/3-C44.3
ICD-O-3
Malignant melanoma, NOS, of skin of other and unspecified parts of face
41.5
13.2
16
*
C43.39
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face other or unspecified histology
41.5
13.2
16
*
F16
ICPC
Eyelid symptom/complaint
4.2
13.2
36
91
Z2221
NOMESCO Finland
Medical doctor
2.2
13.1
148
822
I78.1
ICD-10 Finland
Naevus, non-neoplastic
5.5
12.6
25
48
TQW40, ,
SPAT
3.3
12.3
49
161
S77
ICPC
Malignant neoplasm of skin
9.7
12.2
24
26
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
11.6
11.7
21
19
D03.5
ICD-10 Finland
Melanoma in situ of trunk
23.7
11.7
16
7
8742/2-C44.3
ICD-O-3
Lentigo maligna of skin of other and unspecified parts of face
+∞
11.5
11
*
D03.4
ICD-10 Finland
Melanoma in situ of scalp and neck
+∞
11.5
11
*
D22
ICD-10 Finland
Melanocytic naevi
4.6
11.1
27
62
J01DB01
ATC
cefalexin; oral
2.6
11.0
354
2873
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
5.1
10.9
23
47
S21
ICPC
Skin texture symptom/complaint
2.4
10.8
84
393
8742/3-C44.9
ICD-O-3
Lentigo maligna melanoma of skin, NOS
112.8
10.5
11
*
ZXC15
NOMESCO Finland
Use of photodynamic technique
5.3
10.4
21
41
S29
ICPC
Skin symptom/complaint other
2.2
10.3
107
567
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
11.7
10.1
18
16
C43.30
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face without histology
41.1
10.0
12
*
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
9.4
9.6
19
21
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
5.3
9.4
19
37
B07.9
ICD-10 Finland
Verruca simplex
4.7
9.4
22
49
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
11.0
9.4
17
16
PJA12
NOMESCO Finland
Sentinel node biopsy
2.7
9.3
52
207
XQ845
NOMESCO Finland
Dermatoscopy
5.2
9.2
19
38
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
8.6
9.2
19
23
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
10.4
9.1
17
17
WX002
NOMESCO Finland
Sedation and analgesia
2.0
8.9
115
658
A98
ICPC
Health maint/preventive medicine
4.3
8.8
398
3531
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
4.2
8.6
23
57
XQ848
NOMESCO Finland
Dermatological photography
4.0
8.5
24
62
D03.9
ICD-10 Finland
Melanoma in situ, unspecified
28.2
8.5
11
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
4.8
8.4
19
41
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
11.1
8.4
15
14
ZXE00
NOMESCO Finland
One hour or less
1.8
8.3
180
1218
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
8.2
221
1597
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
9.2
8.1
16
18
C43
ICD-10 Finland
Malignant melanoma of skin
22.5
8.1
11
5
ZQZ00
NOMESCO Finland
Treatment of several skin areas
13.4
7.9
13
10
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
13.4
7.9
13
10
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
3.2
7.6
31
103
C43.32
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face 'superficial spreading' type
18.8
7.6
11
6
8742/3-C44.3
ICD-O-3
Lentigo maligna melanoma of skin of other and unspecified parts of face
81.5
7.4
8
*
D03.1
ICD-10 Finland
Melanoma in situ of eyelid, including canthus
+∞
7.3
7
*
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
6.0
7.3
19
33
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
4.2
7.2
19
47
TQW40
NOMESCO Finland
Remowal of suture of skin
2.6
7.1
41
166
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
7.1
122
762
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
7.2
7.1
16
23
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
7.0
231
1742
H01.0
ICD-10 Finland
Blepharitis
2.9
6.9
32
115
S26
ICPC
Fear of cancer of skin
5.8
6.8
18
32
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
40.7
6.8
8
*
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
17.0
6.8
10
6
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
8.0
6.7
14
18
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.9
6.6
95
559
C08CA13
ATC
lercanidipine; oral
1.9
6.5
86
491
Z01.2
ICD-10 Finland
Dental examination
1.7
6.4
167
1170
TQW80
NOMESCO Finland
Local dermatologic skincare
3.9
6.4
19
51
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
6.4
6.2
15
24
QAE99, ,
SPAT
8.8
6.1
12
14
S15
ICPC
Foreign body in skin
2.5
6.0
38
161

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
203
465
7.60
94.06
1.8
1.3
—
—
—
0
0
323
1415
6.84
67.50
4.4
2.3
—
—
—
0
0
108
342
3.92
29.89
1.5
1.4
—
—
—
0
0
70
168
4.81
27.83
1.4
1.3
—
—
—
0
0
405
3601
6.73
13.36
30.2
25.9
6.66
6.81
e9/l
0.84
392
3474
151
917
2.02
10.09
1.7
1.6
1.33
1.25
mmol/l
0.48
114
742
404
3600
6.06
9.38
30.5
25.9
239.87
240.92
e9/l
0.12
390
3489
404
3601
6.05
9.36
30.2
25.8
30.47
30.41
pg
0.29
394
3526
404
3601
6.05
9.36
30.5
26.1
132.94
132.15
g/l
0.46
394
3523
404
3601
6.05
9.36
30.3
25.9
4.41
4.38
e12/l
0.65
390
3473
404
3601
6.05
9.36
30.6
26.1
39.82
39.16
%
1.43
382
3325
404
3601
6.05
9.36
30.2
25.8
91.81
91.75
fl
0.10
394
3526
399
3538
4.53
9.01
23.8
21.1
139.41
139.57
mmol/l
0.57
388
3434
385
3343
3.17
8.97
19.1
17.6
23.04
26.20
mg/l
1.00
303
2739
399
3543
4.48
8.88
24.6
21.3
3.98
4.00
mmol/l
0.76
389
3436
378
3257
2.85
8.82
5.4
4.9
4.47
4.44
mmol/l
0.13
337
2923
376
3232
2.78
8.80
5.4
4.8
1.52
1.48
mmol/l
0.97
334
2871
366
3120
2.49
8.47
4.7
4.4
1.22
1.24
mmol/l
0.18
321
2751
396
3521
3.87
8.33
13.5
11.5
23.04
23.46
u/l
0.30
377
3363
147
933
1.89
8.32
4.4
3.9
83.19
85.84
%
0.61
140
914
384
3358
2.98
8.27
6.2
5.6
2.55
2.54
mmol/l
0.04
347
2999
219
1587
1.81
7.98
7.0
5.4
0.68
0.64
%
0.52
189
1474
387
3417
3.03
7.80
19.0
16.6
—
—
—
0
0
161
1074
1.82
7.65
3.9
3.4
—
—
—
0
0
363
3119
2.33
7.63
5.6
4.9
1.90
2.03
mu/l
1.29
318
2753
379
3319
2.68
7.63
5.8
5.2
6.02
6.11
mmol/l
0.69
337
2946
371
3221
2.46
7.55
6.8
6.7
39.74
41.06
mmol/mol
2.17
336
2935
221
1634
1.76
7.28
6.9
5.4
58.00
58.51
%
0.24
194
1525
221
1636
1.75
7.23
7.2
5.7
9.15
8.80
%
1.08
192
1521
220
1628
1.75
7.19
7.0
5.4
2.65
2.84
%
0.57
190
1512
218
1610
1.75
7.17
7.6
5.9
—
—
—
0
0
243
1862
1.74
6.91
7.1
6.0
1.22
1.21
mmol/l
0.91
220
1677
146
971
1.78
6.86
2.6
2.9
14997.85
9355.41
umol/l
0.33
117
812
163
1126
1.74
6.67
3.9
3.4
0.47
0.62
e6/l
0.23
135
867
221
1660
1.71
6.66
7.1
5.6
27.55
25.99
%
1.16
192
1542
229
1739
1.71
6.61
7.0
5.2
0.04
0.04
e9/l
0.67
181
1497
208
1542
1.70
6.54
13.8
10.5
0.00
0.00
e9/l
0.76
163
1272
60
300
2.17
6.50
4.3
4.3
—
—
—
0
0
231
1763
1.70
6.50
6.9
5.3
1.75
1.85
e9/l
0.52
185
1551
309
2560
1.82
6.45
4.4
3.9
15.00
15.15
pmol/l
0.47
259
2254
234
1798
1.69
6.37
7.2
5.4
0.17
0.19
e9/l
1.22
187
1565
299
2457
1.78
6.37
5.0
4.7
—
—
—
0
0
333
2829
1.91
6.33
24.7
21.1
15.29
15.60
%
0.39
327
2780
226
1734
1.67
6.08
7.0
5.2
0.59
0.61
e9/l
0.77
177
1486
189
1397
1.65
5.79
4.7
4.1
79.03
90.00
e6/l
0.09
143
1025
169
1223
1.65
5.57
4.0
3.6
107.97
115.70
e6/l
0.04
140
960
252
2015
1.64
5.55
7.3
6.7
1.22
1.21
mmol/l
0.85
206
1714
177
1317
1.60
5.10
6.3
5.6
2.86
4.37
ug/l
0.83
147
1154
307
2607
1.69
5.10
5.1
4.3
14.68
14.90
mm/h
0.06
282
2361
250
2019
1.60
5.08
9.2
9.0
3.81
4.26
e9/l
2.89
205
1769
323
2792
1.71
4.88
8.6
7.8
78.81
80.28
u/l
0.19
298
2595
112
757
1.66
4.70
3.7
3.2
0.90
0.81
ug/l
0.24
84
538
164
1217
1.58
4.68
2.4
2.5
—
—
—
0
0
100
657
1.69
4.67
3.9
3.2
2.02
2.35
e6/l
0.15
56
371
163
1214
1.57
4.55
4.1
4.4
—
—
—
0
0
66
391
1.82
4.40
2.7
3.2
65.45
65.81
g/l
0.13
59
344
34
159
2.24
4.35
3.2
4.3
55.05
52.48
mg/l
0.04
24
130
34
159
2.24
4.35
3.2
4.3
61.02
107.21
mg/l
0.54
24
128
236
1927
1.52
4.22
3.6
3.1
43.18
52.07
u/l
1.70
204
1748
214
1715
1.51
4.16
2.1
2.1
94.76
93.45
pmol/l
0.14
106
856
51
284
1.91
4.12
1.7
1.6
—
—
—
0
0
190
1492
1.51
4.03
2.1
2.3
81.50
80.06
nmol/l
0.29
160
1287
119
846
1.57
3.98
2.7
3.2
540.18
548.87
mosm/kgh2o
0.19
105
727
214
1725
1.50
3.98
4.9
4.5
35.43
34.70
g/l
1.05
193
1609
164
1253
1.51
3.95
6.5
4.1
7.40
7.40
ph
0.09
42
233
13
32
4.16
3.93
1.1
1.3
—
—
—
0
0
17
60
2.91
3.84
1.6
2.2
34.29
32.22
pg
1.65
17
60
25
110
2.35
3.69
3.7
4.8
—
—
—
0
0
173
1355
1.48
3.61
3.1
3.5
2.35
2.35
mmol/l
0.17
145
1165
206
1687
1.44
3.32
2.8
2.6
—
—
—
0
0
138
1051
1.47
3.25
1.7
1.6
19.50
20.65
nmol/l
0.41
111
875
31
158
2.04
3.24
2.3
2.8
35.89
37.04
g/l
0.44
24
136
78
526
1.59
3.22
1.3
1.3
23.55
44.18
iu/ml
1.19
19
168
54
334
1.71
3.12
2.1
2.4
28.29
31.68
u/l
0.57
45
274
17
70
2.49
2.91
2.3
2.6
—
—
—
0
0
35
194
1.88
2.90
3.1
2.9
—
—
—
0
0
116
872
1.46
2.88
2.6
2.8
3.98
5.33
e6/l
0.92
109
788
152
1202
1.42
2.87
3.7
3.1
6.55
6.85
mmol/l
0.44
120
975
287
2534
1.43
2.85
5.0
4.6
—
—
—
0
0
12
43
2.84
2.67
1.0
1.1
—
—
nmol/l
—
0
0
33
185
1.85
2.66
2.2
2.8
10.32
10.07
g/l
0.11
26
162
65
442
1.56
2.59
2.2
1.7
—
—
—
0
0
228
1953
1.37
2.59
5.9
6.3
11.91
11.99
umol/l
0.04
213
1854
9
25
3.66
2.59
1.2
1.3
—
—
—
0
0
152
1223
1.38
2.53
1.9
2.1
161.39
219.99
u/l
0.55
141
1143
149
1195
1.39
2.53
3.8
3.3
515.33
359.43
mg/l
0.12
93
750
116
894
1.41
2.48
6.7
6.8
—
—
—
0
0
12
45
2.72
2.47
1.0
1.2
—
—
—
0
0
59
401
1.55
2.36
3.1
2.7
6.54
9.21
umol/l
1.14
51
350
62
427
1.53
2.34
1.5
1.2
—
—
—
0
0
17
78
2.23
2.34
1.3
1.3
—
1.91
—
0
12
108
830
1.41
2.34
3.4
3.2
2.44
2.46
mmol/l
0.75
95
728
11
40
2.80
2.29
1.2
1.4
0.39
0.74
g/l
—
6
35
36
221
1.69
2.17
1.9
2.9
5.91
5.46
e9/l
0.06
22
159
171
1430
1.33
2.15
3.5
2.8
143.97
147.27
ug/l
0.07
147
1284
154
1269
1.34
2.14
4.5
3.8
7.86
8.39
mg/mmol
0.06
89
778
34
208
1.69
2.08
4.6
4.0
24.94
24.35
mmol/l
0.57
34
201
55
769
0.67
2.03
4.6
4.8
1.02
1.02
kg/l
0.08
11
119
167
1406
1.31
1.96
2.8
3.1
2533.31
1544.89
ng/l
0.50
142
1221
226
1983
1.31
1.96
20.2
18.4
1.23
1.33
inr
1.16
74
550
21
113
1.90
1.95
1.4
1.3
1.19
1.14
g/l
0.37
21
108
10
39
2.60
1.95
1.5
1.1
—
—
—
0
0
5
11
4.59
1.94
1.0
1.6
2.86
1.93
umol/l
—
5
11
14
277
0.49
1.93
5.3
6.3
26.72
24.54
mmol/l
1.28
14
269
50
344
1.52
1.92
3.3
2.6
—
—
—
0
0
56
396
1.48
1.89
3.4
4.3
—
—
—
0
0
32
200
1.65
1.83
1.2
1.3
—
—
—
0
0
41
273
1.56
1.82
3.4
3.9
0.50
0.56
%
—
8
102
86
664
1.37
1.79
1.2
1.2
1.11
1.42
u/ml
0.22
19
156
8
30
2.70
1.73
2.0
2.1
1.99
1.72
ug/l
—
8
25
11
48
2.33
1.72
1.4
1.1
278.50
322.19
u/ml
—
6
26
50
353
1.47
1.71
9.1
8.3
—
—
—
0
0
12
55
2.22
1.69
3.5
2.7
3.36
4.87
e9/l
1.70
12
55
15
76
2.01
1.66
2.1
4.4
—
—
—
0
0
30
190
1.62
1.65
2.2
2.1
13.37
12.05
nmol/l
0.36
25
162
139
1165
1.29
1.64
5.2
4.3
—
—
—
0
0
78
602
1.36
1.63
2.5
1.6
2.75
2.60
g/l
0.14
42
324
17
91
1.91
1.63
1.1
1.1
—
—
—
0
0
10
42
2.41
1.63
1.5
1.6
—
—
—
0
0
99
793
1.33
1.62
1.4
1.3
—
—
—
0
0
55
400
1.43
1.62
2.6
2.6
64.56
70.06
e9/l
0.69
39
322
5
14
3.60
1.62
1.2
1.1
107.20
139.36
nmol/l
—
5
14
40
274
1.51
1.59
3.8
4.1
0.00
1.09
%
—
7
89
6
20
3.03
1.58
1.0
1.6
—
—
—
0
0
97
778
1.32
1.58
1.9
1.6
1.23
1.38
mg/l
0.27
79
621
110
898
1.31
1.58
3.6
3.5
—
—
—
0
0
53
386
1.43
1.55
1.4
1.3
353.33
461.36
titre
0.39
12
88
79
616
1.35
1.55
2.2
3.2
0.82
0.81
mmol/l
0.12
72
577
7
27
2.62
1.52
1.0
1.1
—
—
—
0
0
12
58
2.10
1.50
1.2
1.5
—
—
—
0
0
14
72
1.98
1.50
1.4
1.5
—
—
—
0
0
23
141
1.67
1.45
1.6
2.0
—
—
—
0
0
7
29
2.44
1.40
1.3
1.1
—
—
—
0
0
7
29
2.44
1.40
1.1
1.0
—
—
—
0
0
12
60
2.03
1.39
3.8
3.4
58.92
60.92
%
0.21
12
60
244
2217
1.24
1.39
5.1
5.0
6.60
6.84
mmol/l
1.62
235
2083
47
343
1.42
1.38
1.8
2.1
82.75
162.03
ug/g
1.88
36
263
195
1733
1.24
1.35
4.1
4.3
0.00
0.00
estimate
-0.00
46
358
195
1734
1.24
1.34
5.5
5.8
0.00
0.00
estimate
-0.00
45
324
197
1754
1.23
1.34
4.2
4.3
0.00
0.00
estimate
-0.00
42
314
66
513
1.34
1.33
1.3
1.3
—
—
—
0
0
63
487
1.35
1.32
1.2
1.3
21.20
15.31
u/ml
0.12
15
171
40
288
1.43
1.27
3.8
4.0
0.00
0.11
%
—
7
102
38
272
1.44
1.25
2.0
1.5
—
—
—
0
0
44
325
1.40
1.22
2.0
1.5
—
—
—
0
0
155
1357
1.23
1.21
3.6
4.0
5.78
5.83
ph
—
9
59
12
64
1.90
1.19
1.3
1.2
—
—
—
0
0
21
317
0.64
1.16
4.0
3.5
—
—
—
0
0
5
20
2.52
1.15
1.2
2.1
—
—
—
0
0
16
95
1.71
1.15
2.5
2.5
—
—
—
0
0
66
527
1.30
1.12
2.7
2.4
1.59
1.83
%
2.01
55
474
99
834
1.25
1.09
3.7
4.2
—
—
—
0
0
11
59
1.89
1.08
1.6
1.5
—
—
—
0
0
7
34
2.08
1.03
2.0
2.5
—
—
—
0
0
9
48
1.89
1.01
1.2
2.6
—
—
—
0
0
149
1321
1.20
0.99
3.0
3.5
—
—
—
0
0
9
49
1.85
0.99
1.7
1.4
—
—
—
0
0
133
1169
1.20
0.97
2.6
2.3
64.61
129.51
u/l
0.46
119
1076
0
31
0.00
0.96
0.0
3.8
—
—
—
0
0
178
1608
1.19
0.96
4.0
4.1
36.61
40.41
ng/l
0.23
138
1280
56
448
1.29
0.95
1.4
1.4
—
—
—
0
0
103
886
1.22
0.94
1.8
1.8
1232.36
1198.04
nmol/l
0.10
63
664
10
171
0.57
0.93
4.9
4.5
—
—
—
0
0
32
236
1.39
0.93
3.0
2.6
—
—
—
0
0
10
170
0.58
0.92
3.3
4.0
1.60
1.51
%
—
10
163
15
95
1.60
0.88
1.7
1.6
12338.50
25547.71
e6/l
—
6
70
40
309
1.33
0.88
3.8
3.9
0.44
0.92
%
—
9
122
31
410
0.74
0.87
2.0
2.5
7.63
7.38
ug/l
0.02
26
354
15
96
1.58
0.85
2.9
2.4
—
—
—
0
0
102
885
1.20
0.85
1.9
1.8
127273188.51
16714728.03
pmol/l
0.41
77
700
14
88
1.61
0.85
1.4
1.3
—
—
—
0
0
69
576
1.24
0.84
4.2
2.5
21.10
21.52
%
0.12
61
496
6
115
0.51
0.83
5.0
5.0
0.97
1.21
mmol/l
—
6
105
37
289
1.31
0.77
2.2
1.5
—
—
—
0
0
0
28
0.00
0.76
0.0
1.8
—
9.86
—
0
28
9
53
1.71
0.76
1.3
1.3
—
—
—
0
0
14
92
1.54
0.73
2.2
2.0
12.64
14.62
mg/l
0.30
14
85
5
25
2.01
0.73
1.0
1.2
—
—
—
0
0
11
170
0.64
0.72
3.8
4.1
1.12
0.88
%
0.95
11
163
70
598
1.21
0.70
4.0
2.5
2.22
2.27
g/l
0.43
64
548
16
226
0.70
0.69
2.4
4.0
—
—
—
0
0
7
42
1.68
0.68
1.6
1.3
—
—
—
0
0
7
42
1.68
0.68
1.9
2.6
11.64
7.77
nmol/l
—
7
42
103
914
1.17
0.67
4.0
4.1
—
—
—
0
0
33
412
0.78
0.64
10.0
7.6
118.09
119.63
g/l
0.16
33
407
37
452
0.80
0.61
9.2
7.2
96.49
95.44
%
1.22
37
442
0
20
0.00
0.60
0.0
1.7
—
0.82
—
0
14
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
42
505
0.81
0.60
8.3
7.0
1.14
1.40
mmol/l
0.15
36
405
8
52
1.55
0.59
1.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
42
504
0.81
0.59
8.5
6.9
12.00
11.64
kpa
0.23
42
486
42
504
0.81
0.59
8.6
6.9
5.23
5.11
kpa
0.32
42
486
23
296
0.76
0.57
2.7
3.9
—
—
—
0
0
12
81
1.50
0.57
1.0
1.0
—
—
—
0
0
12
81
1.50
0.57
1.1
1.2
—
—
—
0
0
8
54
1.49
0.57
1.1
1.1
—
—
—
0
0
6
40
1.51
0.52
1.3
1.1
—
—
—
0
0
12
84
1.44
0.50
4.3
4.6
2.87
2.44
mmol/l
—
7
52
21
265
0.78
0.47
4.1
3.6
—
—
—
0
0
5
83
0.60
0.46
1.4
1.3
—
—
—
0
0
5
31
1.62
0.43
3.6
3.4
—
—
—
0
0
5
32
1.57
0.42
1.0
1.0
217.00
236.06
ng/l
—
5
16
5
32
1.57
0.42
1.0
1.0
563.40
560.65
ng/l
—
5
17
27
222
1.23
0.42
1.1
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
15
114
1.33
0.41
1.2
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
72
648
1.13
0.41
4.0
2.5
11.66
12.21
umol/l
0.35
67
594
5
34
1.48
0.40
1.2
1.2
—
—
—
0
0
12
88
1.37
0.40
1.2
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
9
66
1.37
0.38
2.3
3.1
—
—
—
0
0
28
235
1.21
0.37
10.5
9.2
24.44
24.80
mmol/l
0.27
28
228
11
81
1.37
0.36
2.2
2.1
56.00
59.83
%
0.15
11
81
53
472
1.14
0.36
3.7
4.2
4.23
32.28
ug/l
1.05
41
402
49
551
0.87
0.35
8.3
6.7
104.10
104.10
mmol/l
0.00
49
551
6
42
1.43
0.35
1.3
1.1
—
—
—
0
0
6
43
1.40
0.35
1.8
1.1
—
—
—
0
0
14
109
1.29
0.34
1.5
1.6
—
—
—
0
0
30
257
1.18
0.33
2.4
3.4
7.41
7.41
ph
—
5
30
8
62
1.30
0.28
1.0
1.1
—
—
—
0
0
9
116
0.77
0.28
11.2
13.7
—
—
—
0
0
102
960
1.08
0.26
4.7
4.6
0.00
0.00
estimate
-0.00
42
311
34
302
1.14
0.25
1.7
1.5
—
—
—
0
0
6
81
0.74
0.24
4.2
5.0
103.33
104.99
mmol/l
—
6
76
6
81
0.74
0.24
4.2
5.0
10.67
11.28
mmol/l
—
6
76
31
275
1.14
0.24
1.3
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
164.64
—
0
11
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
15
126
1.20
0.21
3.8
3.4
—
—
—
0
0
0
12
0.00
0.21
0.0
4.4
—
49.00
—
0
12
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
10
80
1.26
0.20
2.1
1.9
25.20
30.80
umol/l
—
10
69
6
48
1.25
0.20
1.3
1.2
—
—
—
0
0
6
49
1.23
0.20
3.7
3.2
—
—
—
0
0
22
193
1.15
0.20
2.6
3.2
—
—
—
0
0
109
1044
1.06
0.18
2.3
2.2
2.96
3.22
mg/l
0.71
88
890
7
61
1.15
0.17
1.1
1.1
—
—
—
0
0
8
71
1.13
0.16
9.6
2.6
—
—
—
0
0
20
179
1.12
0.14
1.6
1.4
—
—
—
0
0
13
113
1.16
0.13
1.2
1.5
190.84
263.50
ug/g
—
5
64
20
181
1.11
0.12
1.4
1.4
—
—
—
0
0
5
44
1.14
0.10
1.0
1.0
—
—
—
0
0
5
47
1.06
0.09
2.0
1.6
—
—
—
0
0
5
48
1.04
0.09
2.2
2.9
—
—
—
0
0
62
597
1.05
0.09
2.4
1.9
—
—
—
0
0
83
805
1.04
0.09
3.6
4.0
110.18
277.23
ng/l
1.19
73
698
7
66
1.06
0.08
1.6
1.4
—
—
—
0
0
7
66
1.06
0.08
1.1
1.2
3.50
3.91
mmol/l
—
7
60
40
382
1.05
0.08
8.1
6.9
1.35
1.37
mmol/l
0.03
40
370
8
76
1.05
0.07
2.8
2.9
—
—
—
0
0
8
78
1.03
0.07
1.5
2.9
—
—
—
0
0
8
90
0.89
0.07
1.3
1.1
—
—
—
0
0
15
139
1.08
0.05
2.1
2.7
0.16
0.24
g/l
—
6
47
23
218
1.06
0.05
10.3
8.2
—
—
—
0
0
40
387
1.04
0.04
2.0
3.0
295.52
230.76
ng/l
0.25
33
354
18
186
0.97
0.00
1.4
1.8
0.51
3.42
ug/l
1.11
12
159
11
107
1.03
0.00
1.7
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
0.00
2.4
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
51
0.98
-0.00
1.4
2.1
90.70
89.16
%
—
5
51
0
6
0.00
-0.00
0.0
2.5
—
3082.00
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_MELANOMA_FACE – Melanoma in situ of other and unspecified parts of face

GWS hits: 1

This endpoint is excluded from FinRegistry analyses (omitted endpoint).