This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Melanoma in situ of other and unspecified parts of face
CD2_INSITU_MELANOMA_FACE
melanoma: A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
360 |
4. Check minimum number of eventsNone |
360 |
5. Include endpointsNone |
360 |
6. Filter based on genotype QC (FinnGen only) |
360 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Melanoma in situ of other and unspecified parts of face
based on the number of shared cases.
Similar with more cases:
- Melanoma in situ of other and unspecified parts of face
- Melanoma in situ
- Melanoma in situ
- Malignant melanoma
- Malignant melanoma, excluding all cancers (controls excluding all cancers)
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 360 | 182 | 178 |
| Unadjusted period prevalence (%) | 0.07 | 0.06 | 0.08 |
| Median age at first event (years) | 72.56 | 71.12 | 74.04 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 316
- Matched controls
- 3162
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
+∞
323.0
305
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
63.0
196.5
251
182
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
12.4
71.3
147
207
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
764.5
65.3
62
*
ZZR00
NOMESCO Finland
Flap of skin
29.6
56.7
77
34
L57.0
ICD-10 Finland
Actinic keratosis
8.7
55.4
142
272
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
10.6
41.0
85
106
D03.30
ICD-10 Finland
Melanoma in situ on the lip
+∞
40.5
38
*
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
22.1
33.5
49
26
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
69.5
32.8
37
6
TQW99
NOMESCO Finland
Other minor procedure on skin
8.7
31.9
73
105
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
6.7
29.7
83
160
S18
ICPC
Laceration/cut
3.9
28.7
216
1122
R23.8
ICD-10 Finland
Other and unspecified skin changes
4.7
28.3
114
336
C43.31
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face originating in lentigo maligna
307.3
28.2
28
*
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
9.6
23.4
49
59
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
12.9
23.0
41
36
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
5.4
19.3
62
137
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
9.0
18.7
40
50
D06BB10
ATC
imiquimod; topical
6.3
18.2
50
91
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
70.9
17.9
20
*
ZZA50
NOMESCO Finland
Full thickness skin graft
39.2
17.9
22
6
SPAT1153
SPAT
Removal of sutures
2.8
16.6
158
830
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
9.8
16.4
33
37
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
7.0
15.6
39
62
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
8.4
15.1
33
43
ZXC20
NOMESCO Finland
Use of chemical agents
10.5
15.0
29
30
DHB00
NOMESCO Finland
Excision of lesion of external nose
13.7
13.6
23
18
L82
ICD-10 Finland
Seborrhoeic keratosis
2.9
12.6
87
363
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
4.0
12.6
53
152
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
6.6
12.5
32
53
WX110
NOMESCO Finland
Local anesthesy
2.4
12.1
226
1603
C43.39
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face other or unspecified histology
48.6
12.0
14
*
S77
ICPC
Malignant neoplasm of skin
13.3
11.8
20
16
PJA12
NOMESCO Finland
Sentinel node biopsy
4.4
11.8
44
113
ZXC50
NOMESCO Finland
Cryotherapy
5.3
11.7
36
75
8720/3-C44.3
ICD-O-3
Malignant melanoma, NOS, of skin of other and unspecified parts of face
67.5
11.7
13
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
5.0
11.4
37
82
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
21.0
11.2
16
8
I78.1
ICD-10 Finland
Naevus, non-neoplastic
10.6
11.2
21
21
Z2221
NOMESCO Finland
Medical doctor
2.4
11.0
120
642
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
8.5
10.8
23
29
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
7.2
10.6
25
37
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
24.3
10.3
14
6
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
9.6
10.2
20
22
ZZA00
NOMESCO Finland
Split skin graft
6.3
10.1
26
44
D03.5
ICD-10 Finland
Melanoma in situ of trunk
27.0
9.9
13
5
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
6.7
9.8
24
38
C43.30
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face without histology
56.8
9.7
11
*
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
18.2
9.5
14
8
D03.4
ICD-10 Finland
Melanoma in situ of scalp and neck
103.0
9.5
10
*
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
5.2
8.9
27
56
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
13.2
8.5
14
11
J01DB01
ATC
cefalexin; oral
2.3
8.2
260
2112
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
7.6
8.1
18
25
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
13.5
7.9
13
10
WX002
NOMESCO Finland
Sedation and analgesia
2.2
7.6
93
510
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
12.3
7.6
13
11
S82
ICPC
Naevus/mole
2.6
7.4
58
253
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
11.2
7.4
13
12
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
9.7
7.4
14
15
8742/2-C44.3
ICD-O-3
Lentigo maligna of skin of other and unspecified parts of face
+∞
7.3
7
*
8742/3-C44.9
ICD-O-3
Lentigo maligna melanoma of skin, NOS
+∞
7.3
7
*
D03.9
ICD-10 Finland
Melanoma in situ, unspecified
+∞
7.3
7
*
ZXC15
NOMESCO Finland
Use of photodynamic technique
7.0
6.9
16
24
ZQZ00
NOMESCO Finland
Treatment of several skin areas
11.3
6.9
12
11
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
9.6
6.8
13
14
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
23.1
6.7
9
*
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
11.3
6.3
11
10
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
18.5
6.3
9
5
8742/3-C44.3
ICD-O-3
Lentigo maligna melanoma of skin of other and unspecified parts of face
+∞
6.3
6
*
D22
ICD-10 Finland
Melanocytic naevi
5.1
6.2
18
37
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
8.9
6.1
12
14
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
10.3
6.1
11
11
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_MELANOMA_FACE – Melanoma in situ of other and unspecified parts of face
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).