Traumatic secondary and recurrent haemorrhage

ST19_TRAUMAT_SECONDA_RECUR_HAEMORRHAGE

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — T79.2 Cause of death: ICD-10 — T79.2 2 out of 7 registries used, show all original rules.	56
4. Check minimum number of events None	56
5. Include endpoints None	56
6. Filter based on genotype QC (FinnGen only)	54

Control definitions (FinnGen only)

Control exclude: ST19_ALIQU_COMPLICATI_PRAECO_TRAUMAT

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: T79
Name in latin: Haemorrhagia traumatica secundaria et/sive recurrens

NAME	ST19_TRAUMAT_SECONDA_RECUR_HAEMORRHAGE
CONTROL_EXCLUDE	ST19_ALIQU_COMPLICATI_PRAECO_TRAUMAT
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	T792
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	T792
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Traumatic secondary and recurrent haemorrhage based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	54	25	29
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	68.92	69.10	68.76

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
56: Matched controls
560

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

T79.2

ICD-10 Finland

Traumatic secondary and recurrent haemorrhage

+∞

80.2

X59

ICD-10 Finland

Exposure to unspecified factor

5.6

8.7

WX700

NOMESCO Finland

Respiratory and circulatory monitoring

5.4

7.8

X58

ICD-10 Finland

Exposure to other specified factors

5.7

7.4

W01

ICD-10 Finland

Fall on same level from slipping, tripping and stumbling

4.3

6.8

132

B01AA03

ATC

warfarin; systemic

4.1

6.2

D50.0

ICD-10 Finland

Iron deficiency anaemia secondary to blood loss (chronic)

17.5

6.1

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3012544) pH of Venous blood

4.40

5.02

3.1

3.3

—

(3002032) Base excess in Venous blood by calculation

4.19

4.72

3.0

3.1

2.21

2.06

mmol/l

—

(3022217) INR in Platelet poor plasma by Coagulation assay

219

3.57

4.72

53.3

20.0

1.87

1.37

inr

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

11.19

4.13

1.7

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

3.43

4.04

4.8

7.3

104.06

103.41

mmol/l

0.27

(3042936) Bacteria identified in Isolate by Culture

3.32

3.85

3.2

2.2

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

6.49

3.12

1.7

1.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

3.12

2.97

2.9

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

202

2.54

2.88

3.8

2.6

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

3.06

2.88

2.9

1.6

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

2.65

2.57

7.9

3.1

0.85

0.82

mmol/l

0.48

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

5.45

2.47

3.3

4.3

4.68

3.02

g/l

—

(3003181) Sodium [Moles/volume] in Urine

6.72

2.42

1.8

64.20

43.50

mmol/l

—

(3024928) Oxygen saturation in Venous blood

6.72

2.42

3.6

2.4

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

2.73

2.38

5.3

4.0

270.21

241.89

u/l

0.51

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

2.45

2.36

3.9

2.3

—

(3023368) Bacteria identified in Blood by Culture

145

2.31

2.34

9.5

4.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.55

2.30

2.7

1.6

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

4.66

2.21

2.2

3.6

101.50

87.71

—

(3044640) Blood type and Crossmatch panel - Blood

140

2.25

2.19

4.5

2.4

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

2.54

2.09

9.1

3.8

1.01

1.03

mmol/l

0.07

(3004119) Hemoglobin [Mass/volume] in Venous blood

3.28

2.02

1.3

2.0

140.75

127.52

g/l

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

4.46

1.86

2.8

4.1

219.20

220.17

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

4.11

1.75

2.8

1.4

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

178

2.00

1.71

4.9

3.4

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.41

1.70

2.7

1.6

—

(3000330) Specific gravity of Urine by Test strip

3.81

1.65

13.2

3.9

—

(3026008) Bacteria identified in Urine by Culture

146

1.98

1.60

4.5

2.9

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.81

1.57

1.7

1.2

—

(3022313) Gas panel - Capillary blood

3.55

1.56

4.6

3.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

2.71

1.50

2.3

1.5

—

(3003694) ABO and Rh group [Type] in Blood

107

2.01

1.49

1.6

1.5

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

2.79

1.41

1.3

1.9

0.37

0.81

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

2.01

1.40

5.1

3.9

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

189

1.83

1.36

3.3

4.6

378.66

67.72

ng/l

0.43

145

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.67

1.34

1.3

1.9

2.05

1.56

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

2.64

1.17

1.6

4.1

0.00

g/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

2.43

1.15

3.1

1.8

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.43

1.15

1.9

1.3

—

(3019060) Gas panel - Arterial blood

2.11

1.14

2.9

3.4

—

(3025159) Blasts/100 leukocytes in Blood

2.35

1.13

10.6

4.4

—

0.09

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.51

1.11

3.0

1.2

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.14

1.10

1.3

1.4

—

(3002179) Metamyelocytes/100 leukocytes in Blood

2.28

1.10

9.6

4.0

—

0.85

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.21

1.07

1.1

1.3

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.36

0.97

1.7

3.4

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.96

0.95

3.1

4.0

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

2.28

0.95

8.7

3.5

0.33

0.10

e6/l

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.74

0.84

4.0

1.9

11.36

13.42

umol/l

0.56

(3012516) Albumin [Mass/volume] in Urine

118

1.63

0.82

5.1

3.1

81.23

538.77

mg/l

0.44

(3015736) pH of Urine

164

1.56

0.79

5.6

4.0

—

5.75

—

(3022621) pH of Urine by Test strip

2.19

0.76

6.6

2.3

—

(3000492) Spirometry study

1.85

0.74

1.3

1.4

—

(40760892) CBC W Ordered Manual Differential panel - Blood

204

1.51

0.74

15.6

6.1

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

1.71

0.71

4.6

1.9

18.12

24.86

1.21

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

245

1.48

0.69

2.5

3.1

—

(3018095) Leukocytes [#/volume] in Urine

179

1.48

0.66

7.7

3.8

142.44

57.78

e6/l

0.30

146

(1761868) Lipid panel - Serum or Plasma

158

0.62

0.65

4.3

3.0

—

(3000991) Gas panel - Venous blood

1.70

0.65

11.5

7.3

—

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

0.00

0.61

0.0

4.2

—

109.16

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.85

0.61

4.8

3.6

183.17

170.17

ng/l

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.58

0.56

4.5

1.8

2.48

2.26

g/l

0.54

(3004588) Protein electrophoresis panel - Serum or Plasma

1.60

0.55

1.8

2.7

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.60

0.54

2.2

1.7

—

(3022145) Colonoscopy Study observation

1.59

0.51

2.6

1.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

160

1.39

0.48

7.3

4.3

—

(4035726) Immunohistochemistry procedure

1.46

0.47

1.7

1.3

—

(3000494) Fungus identified in Specimen by Culture

1.53

0.45

3.4

1.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.50

0.45

6.0

10.4

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.44

0.44

1.4

1.3

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.41

0.43

5.7

3.3

2.20

1.75

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.52

0.41

1.4

1.3

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.40

0.0

1.2

—

(40761535) Cells panel - Urine sediment

1.48

0.37

3.2

3.4

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.41

0.36

1.3

1.7

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.42

0.33

4.0

2.5

29.86

29.31

u/l

—

(3002256) Pathology report gross observation

1.29

0.31

1.1

1.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

181

1.26

0.28

2.1

2.0

96.90

93.14

pmol/l

0.14

(3037467) Urinalysis macro (dipstick) panel - Urine

291

1.23

0.26

9.2

4.2

—

(40758558) Short blood count panel - Blood

125

1.27

0.26

12.1

7.9

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.24

0.22

5.8

7.6

1.72

1.36

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.24

0.22

5.6

7.6

0.32

0.71

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.21

0.22

1.4

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

0.22

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

1.07

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.21

0.0

1.2

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.2

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.1

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.21

0.0

1.2

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.20

0.0

1.2

—

(3016879) Cocaine [Presence] in Urine

0.00

0.20

0.0

1.2

—

(3027008) Opiates [Presence] in Urine

0.00

0.20

0.0

1.2

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

2.2

—

(3017044) Thyrotropin receptor Ab [Units/volume] in Serum

0.00

0.20

0.0

2.2

—

3.60

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

0.20

0.0

1.3

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.20

0.0

1.2

—

(40768797) Stomach Pathology biopsy report

1.15

0.18

1.1

1.2

—

(3044889) 12 lead EKG panel

329

1.17

0.16

6.0

4.2

—

(36304419) Bacteria [Presence] in Urine

141

1.19

0.16

2.9

3.0

—

(3000850) Epithelial cells [#/volume] in Urine

128

0.83

0.15

3.2

2.9

6.19

3.83

e6/l

0.28

121

(3013512) EKG study

125

1.16

0.11

6.4

4.2

—

(3041096) Erythrocytes [Presence] in Urine by Automated

116

1.16

0.10

7.8

3.7

—

(40761511) CBC panel - Blood by Automated count

447

1.16

0.09

35.3

14.9

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.11

0.08

1.4

1.5

—

(3009542) Hematocrit [Volume Fraction] of Blood

474

0.95

0.07

52.1

23.9

37.82

40.24

0.89

452

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

410

0.91

0.05

34.1

15.7

75.35

77.73

ml/min/173m2

0.23

339

(40768804) Tissue Pathology biopsy report

173

0.98

0.00

3.0

2.1

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

462

0.98

0.00

38.2

19.2

86.39

82.55

umol/l

0.29

462

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.0

1.5

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.2

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.00

-0.00

4.8

2.8

9.33

12.68

umol/l

—

(4062490) Immunoglobulin typing, IgG

0.00

-0.00

0.0

1.2

—

(3005033) Fetal Nuchal fold Thickness US

0.00

-0.00

0.0

1.4

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.3

—

(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

3.2

—

241.00

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

4.3

—

15.71

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

78.00

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

5.11

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

3.7

—

92.06

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

-0.00

0.0

4.8

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.4

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(3011288) Drugs identified in Urine by Screen method

0.00

-0.00

0.0

1.4

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ST19_TRAUMAT_SECONDA_RECUR_HAEMORRHAGE – Traumatic secondary and recurrent haemorrhage

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Traumatic secondary and recurrent haemorrhage

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Traumatic secondary and recurrent haemorrhage (ST19_TRAUMAT_SECONDA_RECUR_HAEMORRHAGE)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints