Traumatic secondary and recurrent haemorrhage

ST19_TRAUMAT_SECONDA_RECUR_HAEMORRHAGE

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — T79.2 Cause of death: ICD-10 — T79.2 2 out of 7 registries used, show all original rules.	51
4. Check minimum number of events None	51
5. Include endpoints None	51
6. Filter based on genotype QC (FinnGen only)	51

Control definitions (FinnGen only)

Control exclude: ST19_ALIQU_COMPLICATI_PRAECO_TRAUMAT

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: T79
Name in latin: Haemorrhagia traumatica secundaria et/sive recurrens

NAME	ST19_TRAUMAT_SECONDA_RECUR_HAEMORRHAGE
CONTROL_EXCLUDE	ST19_ALIQU_COMPLICATI_PRAECO_TRAUMAT
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	T792
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	T792
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Traumatic secondary and recurrent haemorrhage based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	51	24	27
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	66.80	64.80	68.57

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3012544) pH of Venous blood

4.70

5.05

3.1

3.3

—

(3002032) Base excess in Venous blood by calculation

4.57

4.88

3.1

3.2

2.3

1.9

mmol/l

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

13.22

4.41

1.7

—

(3042936) Bacteria identified in Isolate by Culture

3.55

3.97

2.9

2.2

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

7.90

3.48

1.7

1.3

—

(3032080) INR in Blood by Coagulation assay

162

2.62

2.82

25.7

11.6

2.1

1.4

inr

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

147

2.57

2.72

5.2

3.3

—

(3022217) INR in Platelet poor plasma by Coagulation assay

2.83

2.68

59.8

28.9

—

1.3

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

6.01

2.62

3.3

4.5

4.7

2.9

g/l

—

(3024928) Oxygen saturation in Venous blood

7.75

2.60

3.6

2.6

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

3.03

2.48

3.0

1.3

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

2.69

2.47

8.3

3.3

0.8

mmol/l

0.26

(3003181) Sodium [Moles/volume] in Urine

6.78

2.42

1.8

1.7

64.2

43.5

mmol/l

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.96

2.39

3.0

1.4

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

5.07

2.34

2.2

3.6

101.5

91.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

2.51

2.32

4.1

2.3

—

(3044640) Blood type and Crossmatch panel - Blood

132

2.35

2.24

4.8

2.4

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

2.72

2.19

9.7

4.2

1.0

mmol/l

0.15

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.55

2.05

2.8

1.5

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

4.91

1.99

2.8

4.2

219.2

194.4

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

4.91

1.99

2.8

1.5

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

3.52

1.96

1.1

2.1

145.3

130.0

g/l

—

(3026008) Bacteria identified in Urine by Culture

124

2.18

1.85

4.7

2.9

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

186

2.12

1.82

7.0

4.2

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

3.21

1.79

1.7

1.2

—

(3023368) Bacteria identified in Blood by Culture

127

2.11

1.72

10.2

4.3

—

(3022313) Gas panel - Capillary blood

3.84

1.65

4.6

3.4

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

2.95

1.65

2.3

1.5

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

3.26

1.63

1.3

2.0

1.7

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.42

1.58

2.8

1.6

—

(3018095) Leukocytes [#/volume] in Urine

150

1.97

1.51

7.5

3.7

134.1

62.5

e6/l

0.26

122

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

2.32

1.45

6.5

3.9

275.1

220.0

u/l

1.64

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

2.63

1.45

3.1

1.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.63

1.45

1.9

1.3

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

3.14

1.39

1.6

4.6

0.0

g/l

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.32

1.39

1.3

—

(42870588) Differential panel, method unspecified - Blood

128

1.93

1.36

8.4

4.7

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.69

1.34

1.7

3.7

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

2.06

1.33

5.5

3.8

—

(3022948) Iron [Moles/volume] in Serum or Plasma

2.08

1.30

4.0

1.9

11.4

13.1

umol/l

0.40

(3030981) Hyaline casts [#/volume] in Urine by Automated count

2.58

1.28

8.7

2.7

0.3

0.1

e6/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

168

1.81

1.21

3.5

4.6

416.4

74.4

ng/l

0.42

124

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.37

1.13

1.1

1.3

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

2.02

1.08

4.6

1.9

18.1

24.4

1.01

(3019060) Gas panel - Arterial blood

2.16

1.04

2.6

3.5

—

(3003694) ABO and Rh group [Type] in Blood

1.80

0.98

1.6

1.4

—

(3000991) Gas panel - Venous blood

2.02

0.93

11.6

8.0

—

(3015736) pH of Urine

133

1.68

0.91

6.1

3.9

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.85

0.87

4.5

1.8

2.5

2.2

g/l

0.56

(3004588) Protein electrophoresis panel - Serum or Plasma

1.99

0.85

1.8

3.0

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.79

0.83

3.5

4.1

—

(3000492) Spirometry study

1.97

0.77

1.3

1.4

—

(1761868) Lipid panel - Serum or Plasma

138

0.58

0.74

4.3

2.8

—

(3012516) Albumin [Mass/volume] in Urine

104

1.63

0.73

5.3

3.1

85.1

630.2

mg/l

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

131

1.58

0.72

7.7

4.2

—

(3022145) Colonoscopy Study observation

1.77

0.72

2.6

1.4

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.76

0.71

2.2

1.6

—

(3021960) Folate [Moles/volume] in Serum or Plasma

115

1.57

0.67

1.9

1.4

17.7

23.0

nmol/l

0.64

(3025159) Blasts/100 leukocytes in Blood

1.80

0.65

14.4

4.4

—

0.0

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.71

0.65

6.0

10.3

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.64

0.63

5.7

3.3

2.2

1.8

—

(3002179) Metamyelocytes/100 leukocytes in Blood

1.74

0.63

13.0

4.0

—

0.2

—

(40761535) Cells panel - Urine sediment

1.75

0.59

3.7

3.4

—

(40758558) Short blood count panel - Blood

115

1.43

0.46

12.1

7.6

—

(36304419) Bacteria [Presence] in Urine

115

1.43

0.46

2.9

3.1

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.51

0.45

1.4

1.3

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.68

0.44

5.0

3.7

189.6

173.9

ng/l

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.57

0.42

1.4

1.3

—

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

0.00

0.42

0.0

4.6

—

125.9

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.52

0.41

5.8

8.3

1.7

1.3

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.52

0.41

5.6

8.3

0.3

0.7

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.41

0.0

1.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

223

1.34

0.40

2.6

3.2

—

(3009542) Hematocrit [Volume Fraction] of Blood

335

1.38

0.39

31.5

16.4

38.5

40.1

0.33

243

(4035726)

1.48

0.37

1.7

1.3

—

(3037467) Urinalysis macro (dipstick) panel - Urine

255

1.32

0.37

9.7

4.2

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.41

0.36

4.5

2.6

27.3

30.6

u/l

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

159

1.31

0.33

2.2

2.0

100.2

93.8

pmol/l

0.24

(3000494) Fungus identified in Specimen by Culture

1.40

0.33

3.3

1.4

—

(40768797) Stomach Pathology biopsy report

1.40

0.33

1.1

1.3

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

1.31

0.26

1.6

1.2

1.3

mmol/l

0.09

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.39

0.24

1.4

1.8

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.35

0.24

1.4

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.2

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

1.1

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

0.2

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.21

0.0

1.2

—

(3017044) Thyrotropin receptor Ab [Units/volume] in Serum

0.00

0.21

0.0

2.3

—

3.6

—

(4094501)

0.00

0.21

0.0

1.3

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.1

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.21

0.0

1.2

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.20

0.0

1.2

—

(3027008) Opiates [Presence] in Urine

0.00

0.20

0.0

1.2

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.20

0.0

1.2

—

(3016879) Cocaine [Presence] in Urine

0.00

0.20

0.0

1.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.15

0.18

1.4

1.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

1.22

0.13

23.2

5.7

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.20

0.13

8.6

3.6

—

(3044889) 12 lead EKG panel

290

1.08

0.04

6.1

4.1

—

(3013512) EKG study

111

1.11

0.04

6.9

4.3

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

417

0.91

0.02

38.9

18.6

86.8

82.3

umol/l

0.31

417

(40761511) CBC panel - Blood by Automated count

403

1.09

0.02

36.3

14.5

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

367

0.94

0.02

35.5

15.1

75.5

78.4

ml/min/173m2

0.26

303

(40768804) Tissue Pathology biopsy report

156

0.95

0.01

3.2

2.0

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.5

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.0

1.4

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3015171) Extractable nuclear Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.0

1.5

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.0

1.6

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3002256) Pathology report gross observation

0.98

0.00

1.2

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.2

—

(4062490)

0.00

0.0

1.2

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.0

1.4

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

4.3

—

15.7

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

3.2

—

241.0

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.0

1.3

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

4.8

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

4.3

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

79.3

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.0

2.7

—

113.6

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.0

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

0.92

0.00

5.6

2.7

8.6

10.3

umol/l

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.0

1.4

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ST19_TRAUMAT_SECONDA_RECUR_HAEMORRHAGE – Traumatic secondary and recurrent haemorrhage

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Traumatic secondary and recurrent haemorrhage

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Traumatic secondary and recurrent haemorrhage (ST19_TRAUMAT_SECONDA_RECUR_HAEMORRHAGE)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Relationships between endpoints