Corticotropin deficiency

E4_CORTICOTROPIN_DEFICIENCY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E23.03
  • Cause of death: ICD-10 E23.03

2 out of 7 registries used, show all original rules.

303

4. Check minimum number of events

None

303

5. Include endpoints

None

303

6. Filter based on genotype QC (FinnGen only)

297

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 297 189 108
Unadjusted period prevalence (%) 0.06 0.07 0.05
Median age at first event (years) 57.90 56.42 60.49

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
303
Matched controls
3030
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E23.03
ICD-10 Finland
Lack of ACTH
+∞
307.7
303
*
H02AB09
ATC
hydrocortisone; systemic
1285.1
307.7
283
33
101
Kela drug reimbursment
Anterior pituitary hypofunction
235.0
86.2
85
5
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
324.7
76.2
74
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
17.7
73.8
65
46
E23.00
ICD-10 Finland
Panhypopituitarism
258.6
62.7
62
*
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
113.2
59.5
63
7
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
12.5
56.5
61
60
H03AA01
ATC
levothyroxine sodium; systemic
5.8
52.2
157
471
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
305.3
51.8
51
*
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
130.9
51.7
54
5
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
69.3
46.1
52
9
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
8.3
44.4
66
98
J45.9
ICD-10 Finland
Asthma, unspecified
4.5
33.9
116
366
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.3
32.6
201
959
R03AK08
ATC
formoterol and beclometasone; inhalant
8.9
31.4
42
54
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
10.6
31.2
36
38
E23.05
ICD-10 Finland
Lack of TSH
308.5
28.2
28
*
H02AB06
ATC
prednisolone; systemic
3.8
27.7
202
1039
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
+∞
26.4
25
*
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
79.7
26.3
29
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.4
26.1
79
223
N02AA05
ATC
oxycodone; systemic
4.0
25.0
93
304
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.4
24.5
149
669
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.9
23.6
59
142
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.8
23.5
96
333
J45
ICD-10 Finland
Asthma
4.6
23.5
65
170
E27.2
ICD-10 Finland
Addisonian crisis
+∞
23.2
22
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.7
23.2
61
153
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
3.6
22.9
103
380
H02AA02
ATC
fludrocortisone; oral
129.9
22.9
24
*
N03AE01
ATC
clonazepam; systemic
6.1
22.9
43
80
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.3
22.2
129
557
R11
ICD-10 Finland
Nausea and vomiting
4.7
21.6
57
143
TPH04
NOMESCO Finland
Cathetrisation of vein
3.4
21.1
102
392
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
21.0
71
215
R53
ICD-10 Finland
Malaise and fatigue
3.2
20.9
121
518
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.9
20.9
75
237
AA1AD
NOMESCO Finland
CT of head and brain
3.2
20.7
118
500
UJF32
NOMESCO Finland
Coloscopy
3.2
20.2
114
479
R03BB04
ATC
tiotropium bromide; inhalant
4.4
19.9
57
152
M05BA04
ATC
alendronic acid; oral
4.8
19.5
49
118
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.2
19.4
59
165
N06AX21
ATC
duloxetine; oral
3.8
18.9
69
219
N03AX16
ATC
[U] pregabalin
3.1
18.2
108
463
L04AX01
ATC
azathioprine; systemic
6.7
18.0
30
49
R51.80
ICD-10 Finland
Headache
3.3
18.0
89
343
J01MA12
ATC
levofloxacin; systemic
3.3
17.9
85
319
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.0
17.9
57
164
M05BX04
ATC
denosumab; parenteral
5.4
17.8
38
79
105
Kela drug reimbursment
Adrenal cortical hypofunction
190.7
17.7
18
*
R52.2
ICD-10 Finland
Other chronic pain
6.2
17.2
31
55
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.4
17.2
75
267
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.4
17.1
75
268
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.4
16.7
71
248
WZC00
NOMESCO Finland
Treatment plan or consultation
2.7
16.4
143
746
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
5.4
15.9
33
67
R03BA08
ATC
ciclesonide; inhalant
3.9
15.8
52
153
E23.08
ICD-10 Finland
Hypopituitarism
+∞
15.8
15
*
J45.8
ICD-10 Finland
Mixed asthma
6.7
15.7
26
42
H02AB04
ATC
methylprednisolone; systemic
3.3
15.6
70
252
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.3
15.6
71
258
Z01.8
ICD-10 Finland
Other specified special examinations
2.9
15.5
96
417
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.7
15.4
55
171
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.4
15.4
64
220
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.3
15.2
43
113
SPAT1254
SPAT
Administration of medicine
3.3
15.1
66
234
R03DC03
ATC
montelukast; oral
3.0
15.0
82
331
C03CA01
ATC
furosemide; systemic
2.8
15.0
107
499
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.9
15.0
49
143
R03DA04
ATC
theophylline; systemic, rectal
5.2
14.9
32
67
N05AH04
ATC
quetiapine; oral
2.9
14.8
86
359
N05CD07
ATC
temazepam; oral
3.7
14.8
53
165
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.8
14.6
102
470
N06AX11
ATC
mirtazapine; oral
2.6
14.4
137
734
N06AA09
ATC
amitriptyline; systemic
3.6
14.3
52
163
A02BC02
ATC
pantoprazole; systemic
2.9
14.3
234
1626
N03AX12
ATC
[U] gabapentin; oral
2.9
14.2
83
347
R50.9
ICD-10 Finland
Fever, unspecified
3.1
14.2
71
272
J45.1
ICD-10 Finland
Nonallergic asthma
4.0
13.8
43
121
R06.0
ICD-10 Finland
Dyspnoea
2.6
13.8
110
539
S18
ICPC
Laceration/cut
2.5
13.7
170
1025
SPAT1262
SPAT
Handing over of treatment supplies
3.0
13.7
74
296
E23.3
ICD-10 Finland
Hypothalamic dysfunction, not elsewhere classified
+∞
13.6
13
*
WX892
NOMESCO Finland
Monitored bed care
4.1
13.6
40
108
JN3AD
NOMESCO Finland
Abdominal CT examination
3.4
13.6
55
185
N06AX16
ATC
venlafaxine; oral
3.0
13.6
72
285
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.8
13.5
45
133
N05BA01
ATC
diazepam; systemic, rectal
3.2
13.4
63
232
SPAT1229
SPAT
Assessment of need for aid
4.3
13.4
37
95
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.2
13.4
29
61
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
5.8
13.3
25
46
R03AC13
ATC
formoterol; inhalant
4.6
13.3
33
78
D44.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pituitary gland
52.4
13.0
15
*
N05BA04
ATC
oxazepam; oral
2.6
12.9
108
540
TPH07
NOMESCO Finland
Cathetrisation of artery
3.5
12.6
48
155
M54.4
ICD-10 Finland
Lumbago with sciatica
2.7
12.5
81
356
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.5
12.4
25
49
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.9
12.3
68
274
A12BA01
ATC
potassium chloride; oral
5.8
12.3
23
42
L01BA01
ATC
methotrexate; systemic
5.8
12.3
23
42
J46
ICD-10 Finland
Status asthmaticus
6.4
12.3
21
35
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.6
12.3
93
441
H02AB07
ATC
prednisone; oral
3.0
12.2
61
232
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
19.0
12.2
18
10
M81.9
ICD-10 Finland
Osteoporosis, unspecified
5.4
12.2
25
50
E22.1
ICD-10 Finland
Hyperprolactinaemia
48.7
12.0
14
*
H01AC01
ATC
somatropin; parenteral
48.7
12.0
14
*
N05CF01
ATC
zopiclone; oral
2.4
12.0
122
663
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.3
11.9
51
177
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.7
11.8
40
119
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.3
11.8
49
167
N03AX11
ATC
topiramate; oral
5.6
11.7
23
44
A06AC01
ATC
ispaghula (psylla seeds); oral
2.5
11.7
102
515
N02AX02
ATC
tramadol; systemic, rectal
2.3
11.7
155
942
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.0
11.7
58
220
WZC30
NOMESCO Finland
Teaching
2.8
11.6
69
289
E27.9
ICD-10 Finland
Disorder of adrenal gland, unspecified
+∞
11.5
11
*
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
124.6
11.5
12
*
E23.2
ICD-10 Finland
Diabetes insipidus
124.6
11.5
12
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.9
11.4
63
253
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
11.4
100
506
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
5.9
11.3
21
38
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.3
11.3
31
79
J01FF01
ATC
clindamycin; systemic
2.4
11.3
104
538
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.8
11.3
67
280
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.0
11.2
55
207
SPAT1153
SPAT
Removal of sutures
2.3
11.2
119
655
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
11.2
134
776
L28
ICPC
Limited function/disability (L)
2.8
11.1
67
282
A02BC01
ATC
omeprazole; systemic
2.4
11.1
102
526
NF1AA
NOMESCO Finland
Hip X-ray examination
3.7
11.1
38
114
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.5
11.1
28
67
C10AC01
ATC
colestyramine; oral
8.8
11.0
23
28
A03FA01
ATC
metoclopramide; systemic, rectal
2.5
11.0
91
447
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.0
11.0
54
203
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
9.4
11.0
22
25
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.1
11.0
31
81
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.7
10.8
36
106
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.6
10.7
21
40
R03BA05
ATC
fluticasone; inhalant
2.5
10.7
80
374
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
62.2
10.7
12
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.3
10.7
22
44
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.3
10.7
22
44
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.2
10.7
46
160
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.2
10.5
45
156
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.1
10.5
30
79
E87.6
ICD-10 Finland
Hypokalaemia
5.0
10.4
23
49
C03DA01
ATC
spironolactone; oral
3.0
10.3
51
192
SPAT1301
SPAT
No procedures
2.3
10.3
113
627
D64.9
ICD-10 Finland
Anaemia, unspecified
3.2
10.3
43
147
M47.9
ICD-10 Finland
Spondylosis, unspecified
5.6
10.3
20
38
A07EC01
ATC
sulfasalazine; oral, rectal
3.6
10.2
36
110
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.3
10.2
42
142
E03.89
ICD-10 Finland
Other specified hypothyroidism
4.9
10.2
23
50
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
8.1
10.1
22
29
R96
ICPC
Asthma
3.1
10.1
45
160
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.0
10.1
50
189
R60.0
ICD-10 Finland
Localized oedema
3.0
10.1
50
189
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.9
10.1
53
207
SPAT1263
SPAT
Sampling
2.2
10.0
148
922
J01MA02
ATC
ciprofloxacin; systemic
2.2
10.0
133
795
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.7
10.0
64
277
A02BA02
ATC
ranitidine; systemic
2.5
10.0
74
344
C07AB07
ATC
bisoprolol; oral
2.2
10.0
161
1039
R02
ICPC
Shortness of breath/dyspnoea
2.9
10.0
51
196
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.9
10.0
51
196
A02BC05
ATC
esomeprazole; systemic
2.2
9.9
145
899
ZX120
NOMESCO Finland
Intravenous
3.1
9.8
44
157
X59
ICD-10 Finland
Exposure to unspecified factor
2.5
9.7
73
341
WX402
NOMESCO Finland
General anaesthesia
2.4
9.7
81
397
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
9.6
146
916
R55
ICD-10 Finland
Syncope and collapse
3.0
9.6
47
176
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.5
9.6
73
343
A02BX02
ATC
sucralfate; oral
5.4
9.5
19
37
102
Kela drug reimbursment
Diabetes insipidus
103.1
9.5
10
*
E23.06
ICD-10 Finland
Empty sella
103.1
9.5
10
*
E0000UV, ,
ATC
2.1
9.4
144
903
E23.02
ICD-10 Finland
Neurosecretory dysfunction of the growth hormone
+∞
9.4
9
*
R03BA01
ATC
beclometasone; inhalant
2.6
9.4
60
259
SPAT1255
SPAT
Intravenous administration of medicine
3.8
9.3
30
86
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.9
9.2
28
77
E000001, ,
ATC
2.4
9.2
75
363
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.2
9.2
105
587
A04
ICPC
Weakness/tiredness general
2.6
9.2
58
249
R03AK07
ATC
formoterol and budesonide; inhalant
2.4
9.1
81
407
R01AD09
ATC
mometasone; nasal
2.1
9.0
159
1047
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.5
9.0
32
98
SPAT1310
SPAT
Counselling related to known health issue
2.2
9.0
115
670
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
9.0
63
284
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.1
9.0
39
136
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
4.9
9.0
20
43
UJG02
NOMESCO Finland
Proctoscopy
9.9
8.9
17
18
N05AA02
ATC
levomepromazine; systemic
4.5
8.8
22
52
R03BA02
ATC
budesonide; inhalant
2.4
8.8
75
370
C09CA06
ATC
candesartan; oral
2.3
8.8
87
458
301
Kela drug reimbursment
Growth hormone
51.5
8.7
10
*
R03AC12
ATC
salmeterol; inhalant
4.0
8.7
25
66
N06AB10
ATC
escitalopram; oral
2.3
8.7
83
430
A46
ICD-10 Finland
Erysipelas
2.7
8.6
53
224
R03AC03
ATC
terbutaline; inhalant
2.6
8.6
56
244
H05AA02
ATC
teriparatide; parenteral
28.4
8.5
11
*
E86
ICD-10 Finland
Volume depletion
8.2
8.5
18
23
AA4DG
NOMESCO Finland
Very extensive MRI examination of sella turcica with high intensity magnet
92.5
8.5
9
*
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
92.5
8.5
9
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
8.4
102
580
N03AG01
ATC
valproic acid; systemic, rectal
3.4
8.3
31
98
XX3DW
NOMESCO Finland
Time consuming IT work
2.7
8.3
48
196
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.5
8.3
29
88
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.9
8.3
42
160
SPAT1325
SPAT
Vaccination
2.1
8.3
115
689
WX002
NOMESCO Finland
Sedation and analgesia
2.3
8.2
72
359
R63.4
ICD-10 Finland
Abnormal weight loss
4.3
8.1
21
51
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.3
8.1
21
51
C07AA05
ATC
propranolol; systemic
2.2
8.1
82
433
N04BC06
ATC
cabergoline; oral
34.3
8.1
10
*
ZXC86
NOMESCO Finland
Use of endoscopic device
34.3
8.1
10
*
318
Kela drug reimbursment
Teriparatide
22.7
8.1
11
5
SPAT1312
SPAT
General health counselling
2.1
8.0
110
655
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.0
8.0
176
1238
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.1
8.0
102
591
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
4.0
8.0
23
61
J02AC01
ATC
fluconazole; systemic
2.0
7.9
138
893
JN4AD
NOMESCO Finland
Body CT examination
2.9
7.9
39
146
K59.09
ICD-10 Finland
Constipation, unspecified
3.4
7.9
29
91
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.5
7.9
28
86
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.4
7.9
20
48
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
6.7
7.8
19
30
ZXD05
NOMESCO Finland
Urgent procedure
2.1
7.8
107
635
A04AA01
ATC
ondansetron; systemic, rectal
3.0
7.8
36
130
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.0
7.8
135
871
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.2
7.8
32
108
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
46.2
7.8
9
*
M01AH01
ATC
celecoxib; oral
2.3
7.7
65
317
XQ800
NOMESCO Finland
Prick test
3.1
7.7
34
120
N91.1
ICD-10 Finland
Secondary amenorrhoea
10.4
7.6
14
14
WX725
NOMESCO Finland
Noninvasive ventilation
3.7
7.6
24
68
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.3
7.5
30
99
L86
ICPC
Back syndrome with radiating pain
3.3
7.5
30
99
L95
ICPC
Osteoporosis
4.6
7.5
18
41
N06AX12
ATC
bupropion; oral
3.0
7.5
35
127
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.1
7.5
33
116
R03AC02
ATC
salbutamol; inhalant
2.0
7.5
185
1342
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.7
7.5
42
169
SPAT1260
SPAT
Consultation of another employee
2.3
7.5
65
322
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
82.0
7.4
8
*
M70.6
ICD-10 Finland
Trochanteric bursitis
2.4
7.4
57
267
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
4.3
7.4
19
46
XG410
NOMESCO Finland
Flow-volume spirometry
4.0
7.4
21
55
L04AX03
ATC
methotrexate; systemic
2.7
7.4
41
164
E89.6
ICD-10 Finland
Postprocedural adrenocortical(-medullary) hypofunction
+∞
7.3
7
*
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
16.2
7.3
11
7
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.6
7.3
24
70
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.8
7.3
39
153
A01
ICPC
Pain general/multiple sites
2.8
7.3
39
153
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
4.0
7.2
21
56
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.8
7.2
39
154
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.3
7.2
65
327
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
7.2
148
1006
J01DC02
ATC
cefuroxime; systemic
3.4
7.2
26
81
N06AB05
ATC
paroxetine; oral
3.2
7.1
29
97
D07AC01
ATC
betamethasone; topical
2.0
7.1
120
761
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.6
7.1
24
71
SPAT1240
SPAT
Therapeutic discussion
2.5
7.1
46
199
SPAT1249
SPAT
Treatment-related counselling outside office
1.9
7.1
128
832
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.5
7.0
47
206
G47.3
ICD-10 Finland
Sleep apnoea
2.1
7.0
82
456
N03AX09
ATC
lamotrigine; oral
3.4
7.0
26
82
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.7
7.0
39
156
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.1
7.0
84
472
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
3.5
7.0
24
72
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.9
6.9
34
127
M79.7
ICD-10 Finland
Fibromyalgia
4.0
6.9
20
53
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.0
6.9
20
53
R01AD58
ATC
fluticasone, combinations; nasal
2.0
6.9
90
521
N02BF02
ATC
pregabalin; oral
3.1
6.9
29
99
C08CA13
ATC
lercanidipine; oral
2.4
6.9
53
248
R06AE07
ATC
cetirizine; oral
1.9
6.9
145
988
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.8
6.9
21
58
C01CA24
ATC
epinephrine; parenteral
2.9
6.9
33
122
R33
ICD-10 Finland
Retention of urine
3.1
6.9
30
105
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.7
6.8
37
146
SPAT1216
SPAT
Assessment of functional ability
2.3
6.8
55
263
R06AX13
ATC
loratadine; oral
2.3
6.8
60
298
NH3EA
NOMESCO Finland
Feet X-ray examination with load
7.5
6.8
15
21
UDC00
NOMESCO Finland
Ear microscopy
2.9
6.8
33
123
M54.1
ICD-10 Finland
Radiculopathy
3.9
6.8
20
54
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
6.7
48
217
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
5.7
6.7
18
33
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
6.1
6.7
17
29
M81.4
ICD-10 Finland
Drug-induced osteoporosis
23.1
6.7
9
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.9
6.7
109
681
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.2
6.7
27
90
XCK00
NOMESCO Finland
Perimetry
3.2
6.7
27
90
A10AB05
ATC
insulin aspart; parenteral
2.7
6.6
36
142
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
12.6
6.6
11
9
S97
ICPC
Chronic ulcer skin
3.1
6.6
28
96
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.1
6.6
28
96
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
10.4
6.6
12
12
TQW99
NOMESCO Finland
Other minor procedure on skin
3.4
6.6
24
75
R60.9
ICD-10 Finland
Oedema, unspecified
3.4
6.6
24
75
J01FA15
ATC
telithromycin; oral
2.6
6.6
41
174
M54.5
ICD-10 Finland
Low back pain
1.9
6.5
119
770
ZYC01
NOMESCO Finland
Remote contact by phone
3.1
6.5
28
97
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.1
6.5
28
97
A06AD11
ATC
lactulose; oral
2.4
6.5
47
214
M02AA10
ATC
ketoprofen; topical
2.3
6.5
54
262
TAB00
NOMESCO Finland
Lumbar puncture
3.3
6.4
24
76
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
14.7
6.4
10
7
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.2
6.4
16
27
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
6.2
6.4
16
27
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
11.4
6.3
11
10
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
9.6
6.3
12
13
104
Kela drug reimbursment
Thyroid insufficiency
2.9
6.3
30
110
GD1AD
NOMESCO Finland
Thorax CT examination
3.3
6.3
24
77
C07AB02
ATC
metoprolol; systemic
2.1
6.3
64
336
M13.9
ICD-10 Finland
Arthritis, unspecified
2.8
6.3
32
122
I95.1
ICD-10 Finland
Orthostatic hypotension
5.2
6.3
18
36
A28
ICPC
Limited function/disability NOS
2.3
6.3
52
251
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.7
6.3
34
134
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
6.3
53
258
WZC00, ,
SPAT
2.6
6.3
39
165
J01DB01
ATC
cefalexin; oral
2.3
6.3
258
2167
E23
ICD-10 Finland
Hypofunction and other disorders of pituitary gland
+∞
6.3
6
*
E23.6
ICD-10 Finland
Other disorders of pituitary gland
+∞
6.3
6
*
S20.2
ICD-10 Finland
Contusion of thorax
3.5
6.3
22
67
ZYC06
NOMESCO Finland
Real-time text-based remote transaction
27.3
6.3
8
*
ZXA10
NOMESCO Finland
Bilateral
2.1
6.2
66
352
121
Kela drug reimbursment
Severe hypofunction of sexual glands
6.5
6.2
15
24
L03
ICPC
Low back symptom/complaint
1.9
6.2
92
554
D07AB02
ATC
hydrocortisone butyrate; topical
1.9
6.2
97
596
-50
ICPC
Medication/prescr/renewal
3.9
6.2
18
48
N06AB04
ATC
citalopram; systemic
2.1
6.2
73
406
M89.0
ICD-10 Finland
Algoneurodystrophy
12.9
6.1
10
8
JG1JB
NOMESCO Finland
Defekography with X-ray
12.9
6.1
10
8
T90
ICPC
Diabetes non-insulin dependent
2.0
6.1
74
415
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.5
6.1
21
63
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.5
6.1
21
63
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.9
6.1
91
549
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
6.1
68
370
R42
ICD-10 Finland
Dizziness and giddiness
2.0
6.1
76
431
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
10.3
6.1
11
11
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.3
6.1
15
25
J37.0
ICD-10 Finland
Chronic laryngitis
4.0
6.1
17
44
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.6
6.0
35
143
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.8
6.0
31
119

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
241
252
42.85
241.12
8.4
1.8
195.14
377.51
nmol/l
21.57
229
232
134
32
74.28
235.17
2.3
1.5
—
—
—
0
0
94
73
18.22
103.03
1.8
1.3
12.36
11.66
u/l
0.10
82
62
110
163
10.02
76.54
4.7
3.1
4.23
4.49
pmol/l
1.43
105
147
50
21
28.32
71.42
2.8
1.5
—
—
—
0
0
43
28
17.73
50.41
2.3
1.1
276.44
280.53
mosm/kgh2o
0.30
34
19
237
1086
6.43
45.74
13.1
6.1
1.21
1.22
mmol/l
1.34
229
1005
248
1191
6.96
45.00
12.4
6.8
1.21
1.22
mmol/l
0.56
211
1035
128
395
4.88
39.32
4.2
3.7
0.80
0.82
mmol/l
1.06
120
375
162
618
4.48
37.30
6.9
4.1
—
—
—
0
0
214
1014
4.78
36.36
7.1
4.4
34.42
36.05
g/l
4.08
206
961
40
41
11.09
35.53
2.0
2.1
0.68
0.86
g/l
0.24
22
36
255
1414
6.07
34.50
11.1
4.6
6.51
6.61
mmol/l
0.36
247
1322
104
302
4.72
33.87
5.3
6.1
1.02
1.04
mmol/l
0.28
99
280
174
745
4.14
33.13
6.2
3.8
7.39
7.40
ph
0.59
61
130
117
381
4.37
32.65
3.2
2.2
12.53
13.39
umol/l
0.63
108
359
111
351
4.41
32.16
3.0
2.2
2.26
2.36
g/l
0.93
102
326
105
328
4.37
30.76
3.2
2.3
22.87
22.60
%
0.06
90
290
147
584
3.95
30.67
3.1
2.2
3.05
3.10
mg/l
0.09
138
506
80
203
5.00
30.50
3.0
2.3
10.21
10.27
g/l
0.04
68
187
30
26
12.70
29.59
2.1
1.3
0.54
0.33
g/l
0.96
14
21
30
26
12.70
29.59
2.1
1.3
6.59
7.04
g/l
0.13
14
21
30
26
12.70
29.59
2.1
1.3
2.69
2.34
g/l
0.40
14
20
30
27
12.22
28.89
2.1
1.3
—
—
—
0
0
204
1039
3.95
28.76
4.3
2.3
80.93
75.24
nmol/l
2.43
193
942
71
176
4.96
27.67
3.9
2.2
12.59
13.34
nmol/l
0.23
64
165
77
204
4.72
27.66
4.8
5.0
0.86
0.91
%
0.08
45
77
220
1198
4.05
27.61
13.0
6.3
—
—
—
0
0
37
48
8.64
27.40
1.5
1.5
0.31
0.31
nmol/l
0.00
21
38
72
182
4.88
27.38
4.7
4.8
0.46
0.45
%
0.03
39
61
86
252
4.37
27.09
10.1
8.1
1.29
1.26
mmol/l
0.03
72
207
128
498
3.72
26.89
4.0
2.8
448.18
545.67
mosm/kgh2o
4.24
118
430
165
770
3.51
25.82
6.1
2.3
54.20
58.47
u/l
0.58
159
717
228
1317
3.95
25.14
11.1
6.2
0.19
0.18
e9/l
0.26
205
1170
61
144
5.05
25.06
10.3
3.5
—
—
—
0
0
71
191
4.55
24.84
4.8
5.1
0.05
0.14
%
0.78
39
63
62
150
4.94
24.72
2.0
1.3
24.39
25.52
iu/l
0.09
56
126
287
1993
9.33
24.01
10.6
4.0
14.98
14.68
pmol/l
1.09
278
1818
68
187
4.40
23.02
4.9
5.1
0.00
0.16
%
0.57
34
57
219
1274
3.59
22.94
11.0
5.9
0.64
0.56
e9/l
4.92
200
1110
219
1277
3.58
22.79
11.0
5.9
0.04
0.04
e9/l
0.90
201
1114
209
1196
3.41
22.19
11.1
6.2
8.43
8.38
%
0.10
204
1127
208
1190
3.39
22.03
10.7
5.9
2.60
2.85
%
0.84
203
1120
202
1145
3.29
21.54
10.6
6.0
0.68
0.68
%
0.08
197
1073
221
1325
3.47
21.35
11.1
6.1
11.18
10.69
umol/l
0.11
215
1263
219
1306
3.44
21.35
11.2
5.9
2.43
1.96
e9/l
0.43
200
1177
210
1226
3.32
21.13
10.8
6.0
28.12
28.14
%
0.01
202
1160
194
1087
3.18
20.86
17.5
11.5
1.19
1.20
inr
0.09
68
330
151
736
3.10
20.78
3.1
2.1
295.47
183.99
u/l
0.47
142
702
236
1488
3.65
20.67
14.1
9.4
5.19
4.00
e9/l
1.14
217
1294
68
208
3.93
19.74
3.0
2.7
0.22
0.22
g/l
0.07
61
197
82
292
3.48
18.92
11.0
7.4
103.35
103.93
mmol/l
0.41
82
292
56
155
4.21
18.59
6.5
4.4
7.44
7.42
ph
0.39
14
17
194
1132
2.98
18.57
4.3
2.7
108.51
100.67
ug/l
0.32
186
1058
202
1214
2.99
18.14
10.2
5.8
56.68
57.00
%
0.12
195
1146
28
43
7.07
17.79
3.9
4.0
57.21
62.37
%
1.02
28
43
90
352
3.21
17.72
3.0
1.9
—
—
—
0
0
168
925
2.83
17.65
6.7
3.6
22.96
32.02
ng/l
1.19
139
609
24
32
8.06
17.21
1.2
1.3
0.56
0.47
nmol/l
0.57
24
27
92
373
3.11
16.95
1.6
1.4
409.41
550.11
titre
0.37
17
93
65
213
3.61
16.90
7.4
4.8
2.26
1.94
mmol/l
0.30
56
173
27
43
6.80
16.58
3.2
3.4
4.84
5.04
e9/l
0.13
27
43
27
43
6.80
16.58
3.1
2.5
16.06
15.96
%
0.03
15
22
59
184
3.74
16.49
1.3
1.2
107.47
170.74
iu/ml
0.72
30
83
151
818
2.69
15.91
4.3
3.2
2.35
2.35
mmol/l
0.12
131
733
132
670
2.72
15.83
3.9
3.3
928.61
1082.85
ng/l
0.22
115
576
261
1890
3.75
15.55
7.7
4.2
13.92
11.32
mm/h
2.25
253
1758
27
46
6.35
15.54
4.3
2.6
—
—
—
0
0
44
117
4.23
15.30
10.6
10.7
—
—
—
0
0
162
931
2.59
14.82
2.6
1.9
105.99
95.24
pmol/l
1.53
92
479
51
157
3.70
14.45
1.9
1.3
140.37
154.55
u/ml
0.11
45
146
27
50
5.83
14.28
5.9
2.3
2.94
2.76
mmol/l
0.10
21
33
111
539
2.67
14.27
2.0
1.5
19.22
21.32
nmol/l
0.78
103
461
183
1140
2.53
13.74
3.9
2.4
—
—
—
0
0
33
76
4.75
13.71
1.6
1.3
261.05
306.03
ug/g
0.62
21
39
35
87
4.42
13.23
12.6
3.8
—
—
—
0
0
239
1715
2.86
13.02
8.3
4.0
—
—
—
0
0
292
2372
7.36
12.93
11.0
4.7
1.73
1.87
mu/l
0.84
281
2187
101
491
2.59
12.73
1.8
1.7
80488224.09
431.99
pmol/l
0.49
82
419
136
762
2.42
12.59
3.8
2.2
—
—
—
0
0
53
183
3.30
12.52
2.8
3.2
74.49
70.80
e9/l
0.30
41
144
25
49
5.47
12.44
2.0
1.5
—
—
—
0
0
24
26
9.92
12.23
1.2
1.4
—
—
nmol/l
—
0
0
66
265
2.91
12.01
2.9
3.1
1.91
1.76
%
0.56
55
243
47
156
3.38
11.80
1.4
2.2
—
—
—
0
0
51
184
3.13
11.15
9.0
10.3
—
—
—
0
0
21
39
5.71
11.04
3.4
2.6
—
—
—
0
0
52
193
3.05
10.82
2.2
2.6
65.70
67.21
g/l
0.71
47
180
129
745
2.27
10.74
5.2
2.8
—
—
—
0
0
88
434
2.45
10.50
2.1
1.6
1221.24
1177.94
nmol/l
0.16
70
336
54
209
2.93
10.43
6.4
3.5
—
—
—
0
0
27
66
4.39
10.39
4.0
2.7
24.91
25.33
mmol/l
0.18
27
66
66
285
2.68
10.37
2.5
1.5
—
—
—
0
0
184
1244
2.22
10.20
6.2
3.4
0.00
0.00
estimate
-0.00
60
259
22
29
8.09
10.09
2.4
4.2
—
—
—
0
0
41
140
3.23
9.79
1.4
1.3
—
—
—
0
0
15
10
15.70
9.61
2.3
1.2
185.40
48.80
nmol/24h
—
15
10
67
303
2.56
9.54
2.0
1.4
—
—
—
0
0
118
684
2.19
9.49
7.1
3.7
0.00
0.00
estimate
-0.00
58
242
182
1247
2.15
9.47
7.7
4.6
0.00
0.00
estimate
-0.00
58
247
48
184
2.91
9.39
3.5
3.7
94.02
75.44
ng/l
0.52
41
168
183
1260
2.14
9.36
6.3
3.4
0.00
0.01
estimate
0.50
58
231
103
570
2.22
9.25
1.9
1.8
0.79
1.26
mg/l
1.37
79
452
119
699
2.16
9.19
5.0
3.6
—
—
—
0
0
35
116
3.28
8.75
8.5
4.7
—
—
—
0
0
152
997
2.05
8.61
5.3
3.2
6.20
5.91
ph
—
5
89
47
187
2.79
8.57
10.5
9.4
1.25
1.28
mmol/l
0.08
47
181
20
30
7.06
8.51
1.2
1.3
—
—
—
0
0
18
37
5.11
8.47
3.7
3.4
—
—
—
0
0
118
711
2.08
8.37
5.5
3.1
—
—
—
0
0
103
591
2.13
8.30
1.8
1.4
2.37
2.25
g/l
0.30
80
365
278
2348
3.23
7.96
8.0
5.4
40.46
39.59
mmol/mol
0.73
267
2216
119
730
2.04
7.96
3.1
3.1
6.65
7.60
mmol/l
1.44
100
628
33
112
3.18
7.94
8.0
3.7
0.75
0.66
%
0.58
33
112
108
642
2.06
7.85
1.5
1.3
0.63
1.76
u/ml
1.99
36
171
20
49
4.30
7.66
3.3
2.8
—
—
—
0
0
297
2714
5.76
7.22
42.6
14.9
78.16
74.96
umol/l
1.42
297
2714
49
217
2.50
7.19
6.4
4.6
—
—
—
0
0
108
661
1.98
7.12
3.3
3.3
1402.28
143.97
mg/l
0.70
63
426
291
2561
4.44
7.07
38.8
13.0
19.65
21.49
mg/l
0.71
272
1993
91
528
2.03
6.94
4.4
2.5
7.07
4.54
e6/l
1.05
86
477
112
700
1.95
6.91
5.3
3.0
0.21
0.34
e6/l
0.84
95
525
119
766
1.91
6.68
5.4
3.1
111.65
157.61
e6/l
0.16
103
589
6
0
+∞
6.27
1.5
0.0
2.76
—
mu/l
—
6
0
6
0
+∞
6.27
1.3
0.0
1.58
—
nmol/l
—
6
0
19
53
3.76
6.14
1.3
1.5
—
—
—
0
0
107
681
1.88
6.12
5.1
2.9
—
—
—
0
0
11
11
10.32
6.08
1.5
1.5
—
—
—
0
0
22
69
3.36
6.00
1.4
3.6
28.40
41.01
mg/l
1.05
15
56
18
50
3.76
5.85
1.4
1.5
—
—
—
0
0
130
889
1.81
5.85
5.7
3.6
63.57
68.09
e6/l
0.03
107
637
47
224
2.30
5.84
1.4
1.4
—
—
—
0
0
160
1164
1.79
5.84
23.0
9.1
0.30
0.00
e9/l
0.49
139
955
101
640
1.87
5.80
5.8
3.7
94.01
93.11
%
0.13
96
628
16
41
4.06
5.79
1.3
1.7
—
—
—
0
0
16
41
4.06
5.79
1.1
1.1
—
—
—
0
0
25
88
3.01
5.66
1.2
1.3
—
—
—
0
0
11
13
8.73
5.60
1.4
1.1
152.00
169.67
mmol/24h
0.21
11
13
59
314
2.09
5.58
3.0
2.3
126.87
111.86
ug/g
0.13
51
249
279
2456
2.72
5.56
6.4
4.4
5.84
5.91
mmol/l
0.30
270
2275
21
69
3.20
5.33
1.4
3.6
24.01
30.26
mg/l
0.51
14
55
9
8
11.55
5.32
1.9
2.8
90.11
115.13
nmol/l
—
9
8
56
300
2.06
5.19
1.4
1.3
—
—
—
0
0
106
705
1.77
5.09
4.0
3.8
7.05
8.08
mg/mmol
0.16
61
438
73
436
1.89
4.95
3.7
2.7
2.50
2.44
mmol/l
1.70
65
386
16
38
4.39
4.90
1.1
1.0
7.83
23.30
iu/ml
—
7
10
10
13
7.91
4.89
1.2
1.5
—
—
—
0
0
16
47
3.54
4.81
1.3
4.4
—
—
—
0
0
9
10
9.23
4.81
2.3
2.0
—
—
—
0
0
15
35
4.45
4.70
1.1
1.1
—
—
—
0
0
10
14
7.34
4.69
1.5
1.1
1.89
1.73
mmol/l
—
10
14
61
362
1.86
4.18
1.7
1.6
—
—
—
0
0
16
52
3.19
4.15
7.9
5.4
—
—
—
0
0
73
460
1.77
4.11
9.1
3.6
58.54
147.98
ng/l
1.28
57
340
211
1750
1.68
4.10
5.3
3.7
—
—
—
0
0
72
453
1.77
4.07
1.7
1.9
—
—
—
0
0
31
145
2.27
4.03
1.1
1.1
—
6.20
titre
—
0
5
7
7
10.20
4.03
1.4
1.9
132.29
146.14
nmol/l
—
7
7
59
351
1.85
4.01
1.4
1.2
—
—
—
0
0
10
18
5.71
4.01
1.9
1.4
—
—
—
0
0
84
555
1.71
4.00
6.6
3.5
1.01
1.02
kg/l
—
10
63
212
1768
1.66
3.95
6.4
3.1
57.96
43.31
u/l
1.78
203
1671
22
90
2.56
3.81
28.5
9.2
—
—
—
0
0
11
24
4.71
3.78
2.5
1.6
—
—
—
0
0
12
29
4.26
3.74
2.8
9.3
6.42
6.45
mmol/l
0.02
12
24
50
289
1.87
3.71
1.9
1.6
—
—
—
0
0
137
1041
1.58
3.68
2.6
2.1
—
—
—
0
0
12
30
4.12
3.63
3.0
3.0
—
—
—
0
0
36
189
2.03
3.52
1.9
1.4
—
—
—
0
0
6
6
10.17
3.51
1.2
1.0
—
—
—
0
0
33
170
2.06
3.40
4.6
2.5
5.84
5.74
e9/l
0.02
21
146
8
14
5.84
3.36
1.1
1.0
—
—
—
0
0
18
71
2.63
3.36
2.3
1.8
346.63
4.56
iu/l
—
9
22
288
2673
2.56
3.34
38.3
12.0
—
—
—
0
0
6
7
8.71
3.27
1.2
1.0
—
—
—
0
0
94
673
1.58
3.18
1.5
1.4
—
—
—
0
0
13
44
3.04
3.17
1.6
1.8
—
—
—
0
0
9
20
4.60
3.13
1.3
1.3
—
—
—
0
0
49
298
1.77
3.08
3.5
2.7
6.70
7.68
umol/l
0.24
39
262
298
2850
3.76
3.07
53.0
19.4
39.42
40.49
%
2.16
276
2695
10
27
3.79
2.90
1.5
1.6
—
—
—
0
0
6
9
6.77
2.88
1.0
1.0
—
—
—
0
0
32
175
1.93
2.81
1.4
1.3
—
32.14
—
0
11
44
269
1.74
2.72
1.5
1.6
—
—
—
0
0
8
20
4.08
2.58
1.3
1.1
—
—
—
0
0
13
50
2.67
2.56
3.3
1.7
1.33
0.78
nmol/l
—
8
42
22
109
2.10
2.53
1.3
1.2
—
—
—
0
0
11
37
3.05
2.51
1.7
1.5
—
—
—
0
0
33
190
1.83
2.50
6.6
3.4
—
—
—
0
0
40
245
1.73
2.47
2.9
4.1
3.05
27.76
ug/l
0.76
33
193
6
12
5.08
2.41
1.5
2.6
2588.33
2091.25
ml
—
6
12
24
127
1.97
2.33
2.9
2.2
—
—
—
0
0
9
28
3.28
2.32
1.3
1.4
—
—
—
0
0
9
28
3.28
2.32
1.8
1.6
32.44
32.86
pg
—
9
28
10
34
3.01
2.30
1.3
1.2
—
—
—
0
0
66
470
1.52
2.23
1.6
1.3
35.97
28.17
iu/ml
0.21
20
158
5
9
5.63
2.22
1.6
6.1
45.30
48.17
%
—
5
9
76
561
1.47
2.15
6.0
3.3
—
—
—
0
0
13
55
2.42
2.15
1.5
1.3
—
—
—
0
0
5
10
5.06
2.08
2.2
2.6
227.20
828.10
u/ml
—
5
10
5
10
5.06
2.08
4.0
3.0
—
—
—
0
0
17
83
2.11
2.05
1.5
1.2
—
—
—
0
0
8
26
3.13
2.03
1.0
1.1
—
—
—
0
0
8
26
3.13
2.03
2.6
2.3
6.96
3.72
nmol/l
—
8
26
7
21
3.39
1.97
16.3
9.0
11.70
10.48
%
—
7
21
6
16
3.80
1.94
1.8
1.3
—
—
—
0
0
5
12
4.22
1.83
1.0
2.5
—
—
—
0
0
55
394
1.48
1.80
4.5
2.9
1.79
2.47
e6/l
0.36
35
213
15
74
2.08
1.78
1.1
1.1
—
—
—
0
0
16
81
2.03
1.78
2.4
3.8
0.19
0.14
g/l
—
5
34
31
195
1.66
1.77
2.7
2.4
3.35
6.29
ug/l
1.80
23
173
83
648
1.39
1.71
3.3
2.8
326.14
5747.42
umol/l
2.46
71
563
10
41
2.49
1.66
1.2
1.7
—
—
—
0
0
7
25
2.84
1.66
1.0
1.6
13.08
17.46
ug/l
—
7
25
5
14
3.61
1.62
3.0
2.4
55.29
44.83
umol/l
—
5
14
7
26
2.73
1.59
1.1
1.0
—
—
—
0
0
6
20
3.04
1.59
1.2
1.2
—
—
—
0
0
19
107
1.83
1.58
2.7
1.6
—
—
—
0
0
7
27
2.63
1.52
3.4
2.8
—
38.38
—
0
8
5
16
3.16
1.44
4.4
6.9
—
—
—
0
0
9
40
2.29
1.41
3.6
1.3
—
—
—
0
0
9
40
2.29
1.41
1.6
1.3
—
75.14
—
0
5
82
658
1.34
1.41
7.1
6.9
—
—
—
0
0
12
60
2.04
1.40
1.3
2.3
182.40
96.49
ug/min
—
5
32
6
23
2.64
1.37
1.0
1.2
—
—
—
0
0
6
23
2.64
1.37
1.3
1.1
—
—
—
0
0
14
75
1.91
1.36
1.7
1.5
—
—
—
0
0
16
90
1.82
1.36
1.6
1.5
—
—
—
0
0
18
291
0.59
1.33
1.5
1.4
—
—
—
0
0
36
253
1.48
1.32
2.0
1.4
—
—
—
0
0
80
972
0.76
1.30
3.2
2.8
—
—
—
0
0
5
19
2.66
1.22
2.6
2.9
9.60
9.31
mmol/l
—
5
19
84
692
1.30
1.19
1.8
1.7
1.52
1.37
mmol/l
1.02
70
590
5
20
2.52
1.15
3.4
2.5
—
—
—
0
0
12
65
1.88
1.15
3.0
1.7
—
—
—
0
0
41
305
1.40
1.13
1.3
1.2
—
—
—
0
0
27
185
1.50
1.13
1.4
1.5
—
—
—
0
0
208
2227
0.79
1.09
42.2
16.8
332.53
332.53
g/l
0.00
208
2220
7
33
2.15
1.06
2.7
1.6
—
—
—
0
0
16
98
1.67
1.05
1.6
1.5
—
—
—
0
0
16
98
1.67
1.05
1.6
1.5
—
—
—
0
0
16
98
1.67
1.05
1.6
1.5
—
—
—
0
0
19
122
1.59
1.05
3.3
3.3
—
—
—
0
0
80
676
1.25
0.92
4.4
4.9
2.57
2.70
ug/l
0.05
72
606
57
463
1.28
0.90
1.6
1.3
5.78
10.43
u/ml
0.58
23
185
13
80
1.65
0.86
4.4
3.1
—
—
—
0
0
22
155
1.45
0.84
2.7
2.2
—
—
—
0
0
15
97
1.57
0.83
2.8
3.2
12.01
1951.07
u/ml
—
10
81
6
32
1.89
0.82
2.2
2.6
—
—
—
0
0
6
32
1.89
0.82
2.2
2.6
102.83
106.56
mmol/l
—
6
32
6
32
1.89
0.82
2.2
2.6
3.83
4.00
mmol/l
—
6
32
15
98
1.56
0.80
1.5
1.5
—
—
—
0
0
11
66
1.69
0.79
3.9
4.2
—
—
—
0
0
253
2425
1.26
0.77
4.7
3.9
1.62
1.27
mmol/l
2.76
227
2253
10
59
1.72
0.76
2.0
1.1
—
—
—
0
0
5
24
2.10
0.75
1.0
3.0
—
—
—
0
0
30
229
1.34
0.74
1.3
1.2
—
—
—
0
0
11
68
1.64
0.72
1.4
1.1
—
—
—
0
0
5
27
1.87
0.68
1.2
1.2
—
—
—
0
0
5
29
1.74
0.64
2.4
2.4
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
266.91
—
0
11
260
2518
1.23
0.58
5.4
4.4
4.56
4.72
mmol/l
1.43
239
2366
32
257
1.27
0.58
4.6
2.1
29.65
34.16
u/l
0.33
26
213
9
63
1.44
0.53
2.0
1.8
—
—
—
0
0
6
40
1.51
0.52
1.0
1.1
—
—
—
0
0
6
40
1.51
0.52
1.0
1.1
—
—
—
0
0
263
2559
1.21
0.50
5.7
4.8
2.61
2.80
mmol/l
2.56
238
2393
13
95
1.38
0.44
2.6
2.8
—
—
—
0
0
9
129
0.69
0.44
1.3
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
6
44
1.37
0.34
1.7
1.1
—
—
—
0
0
256
2504
1.14
0.33
5.3
4.3
1.42
1.49
mmol/l
2.04
231
2335
20
166
1.22
0.30
1.3
1.2
—
—
—
0
0
26
222
1.19
0.30
1.7
1.7
—
—
—
0
0
9
75
1.21
0.25
1.2
1.2
—
—
—
0
0
5
41
1.22
0.22
2.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
6.29
—
0
12
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
10
121
0.82
0.18
1.2
1.1
—
—
—
0
0
26
284
0.91
0.14
2.2
1.5
—
—
—
0
0
42
401
1.06
0.08
2.9
2.9
0.63
0.78
ug/l
1.19
31
251
8
90
0.89
0.07
1.4
1.6
—
—
—
0
0
15
159
0.94
0.03
1.4
1.7
—
—
—
0
0
15
159
0.94
0.03
3.9
2.3
19.63
51.47
u/ml
1.23
15
151
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
25.86
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
1.90
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
19.60
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: E4_CORTICOTROPIN_DEFICIENCY – Corticotropin deficiency

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).