Other mosquito-borne viral fevers

AB1_OTHER_MOSQUITO_FEVER

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A92, A93
  • Hospital discharge: ICD-9 06[6]
  • Hospital discharge: ICD-8 06[7]
  • Cause of death: ICD-10 A92, A93
  • Cause of death: ICD-9 06[6]
  • Cause of death: ICD-8 06[7]

2 out of 7 registries used, show all original rules.

77

4. Check minimum number of events

None

77

5. Include endpoints

None

77

6. Filter based on genotype QC (FinnGen only)

77

Control definitions (FinnGen only)

Control exclude
AB1_ARTHROPOD

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 699 362 335
Only index persons 635 339 296
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 46.07 48.04 43.79
Only index persons 45.47 47.71 42.91

-FinnGen-

Key figures

All Female Male
Number of individuals 77 42 35
Unadjusted period prevalence (%) 0.01 0.01 0.02
Median age at first event (years) 50.08 48.74 51.70

-FinRegistry-

Age distribution of first events

010203040506070800102030405060708090100110120130140AgeIndividuals

-FinnGen-

Age distribution of first events

030405060700246810121416182022AgeIndividuals

-FinRegistry-

Year distribution of first events

1970197519801985199019952000200520102015202020220102030405060708090100110120130YearIndividuals

-FinnGen-

Year distribution of first events

1970200020052010201520202023024681012141618YearIndividuals

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
73
Matched controls
728
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A92.8
ICD-10 Finland
Other specified mosquito-borne viral fevers
+∞
55.4
46
*
A92.0
ICD-10 Finland
Chikungunya virus disease
+∞
7.4
7
*
M13.9
ICD-10 Finland
Arthritis, unspecified
8.7
7.1
15
21

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6
6
10.70
3.56
1.3
1.5
—
—
—
0
0
26
143
2.24
2.61
3.7
5.6
—
—
—
0
0
24
139
2.06
2.07
1.4
1.7
1.31
1.25
mg/l
0.04
19
113
12
53
2.50
1.92
2.8
3.4
—
—
—
0
0
26
160
1.94
1.88
2.7
3.6
0.00
0.00
estimate
—
10
48
23
136
1.99
1.86
1.4
1.3
2.57
2.24
g/l
0.77
16
83
6
19
3.33
1.69
1.3
1.2
—
—
—
0
0
7
25
2.97
1.69
1.3
1.2
0.18
0.23
g/l
—
7
25
42
312
1.76
1.62
4.6
4.9
0.00
0.00
estimate
—
10
53
42
312
1.76
1.62
3.1
3.5
0.00
0.00
estimate
—
10
52
7
27
2.75
1.55
1.3
1.2
1.04
1.21
g/l
—
7
27
42
317
1.71
1.49
3.1
3.5
0.00
0.00
estimate
—
10
47
25
163
1.79
1.48
3.1
4.3
—
—
—
0
0
22
139
1.82
1.44
1.5
2.0
—
—
—
0
0
19
116
1.85
1.38
1.2
1.2
8.06
43.04
iu/ml
—
5
42
9
43
2.23
1.35
1.6
3.5
—
—
—
0
0
8
35
2.43
1.31
1.4
1.1
—
—
—
0
0
52
431
1.64
1.17
3.3
3.7
—
—
—
0
0
10
51
2.10
1.17
1.1
1.6
—
—
—
0
0
5
20
2.60
1.17
1.8
2.2
11.50
10.66
mg/l
—
5
20
13
74
1.91
1.15
1.4
1.2
—
—
—
0
0
26
183
1.64
1.15
2.5
3.3
—
—
—
0
0
15
90
1.83
1.14
1.1
1.7
—
—
—
0
0
8
41
2.06
1.12
1.3
1.2
—
16.30
—
0
5
18
115
1.74
1.12
1.3
1.3
2.10
9.03
u/ml
—
6
49
33
248
1.58
1.11
3.4
3.4
—
—
—
0
0
22
150
1.65
1.09
1.4
1.3
0.85
1.92
u/ml
1.07
11
45
32
240
1.57
1.08
2.1
2.8
—
—
—
0
0
7
34
2.16
1.06
1.7
2.4
—
—
—
0
0
16
101
1.74
1.04
2.5
3.6
12.90
93.15
ng/l
—
10
73
7
37
1.98
0.97
1.0
1.2
—
—
—
0
0
29
219
1.52
0.93
2.5
3.2
8.53
58.08
e6/l
1.35
21
154
6
29
2.16
0.91
1.3
3.7
25.60
24.29
mmol/l
—
6
29
23
167
1.54
0.87
3.2
3.8
—
—
—
0
0
38
307
1.47
0.87
4.7
5.0
55.73
56.69
%
0.19
38
287
10
58
1.83
0.84
1.2
1.2
—
—
—
0
0
26
199
1.46
0.76
7.2
5.2
—
—
—
0
0
7
38
1.92
0.76
1.9
2.5
63.66
66.70
g/l
—
7
33
70
654
1.77
0.75
12.5
14.3
139.91
139.78
mmol/l
0.23
70
640
5
25
2.07
0.74
1.2
5.5
—
—
—
0
0
10
61
1.73
0.72
1.1
1.4
—
—
—
0
0
5
27
1.91
0.70
2.2
6.0
—
—
—
0
0
19
139
1.49
0.69
3.4
3.3
—
—
—
0
0
13
87
1.59
0.68
1.2
1.4
—
—
—
0
0
22
168
1.43
0.65
2.0
2.5
—
—
—
0
0
70
659
1.68
0.64
12.7
14.2
4.01
3.96
mmol/l
0.93
70
645
28
224
1.39
0.64
8.9
4.9
1.09
1.15
inr
0.25
14
66
28
225
1.38
0.62
2.5
3.7
22.24
37.17
ng/l
0.54
16
144
12
81
1.57
0.61
1.9
1.2
—
—
—
0
0
0
21
0.00
0.61
0.0
1.1
—
—
—
0
0
46
402
1.36
0.60
3.2
3.8
—
20.33
—
0
6
6
38
1.63
0.56
1.2
2.4
1.40
1.62
%
—
6
38
6
39
1.58
0.54
1.3
3.2
125.67
128.33
g/l
—
6
39
11
75
1.54
0.54
1.3
2.3
21.82
22.76
%
0.09
11
61
9
64
1.46
0.54
1.7
2.1
278.78
384.25
nmol/l
—
9
57
49
437
1.33
0.53
2.2
3.5
—
—
—
0
0
17
130
1.39
0.49
2.4
2.7
0.63
0.71
ug/l
—
9
83
31
262
1.31
0.48
2.2
2.0
—
—
—
0
0
7
49
1.47
0.47
1.0
1.1
—
—
—
0
0
12
87
1.45
0.45
1.8
2.2
13.28
12.87
umol/l
0.08
12
76
38
334
1.27
0.43
3.7
6.9
9.46
10.24
umol/l
0.33
38
318
5
33
1.55
0.42
1.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
5
34
1.50
0.41
1.6
2.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.5
—
—
—
0
0
0
17
0.00
0.41
0.0
2.9
—
—
—
0
0
11
80
1.44
0.41
1.5
2.3
2.47
2.34
g/l
0.27
11
69
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
9
66
1.41
0.40
1.2
1.9
—
—
—
0
0
9
70
1.32
0.38
1.3
1.5
—
—
—
0
0
21
174
1.28
0.37
5.6
6.9
—
—
—
0
0
33
291
1.23
0.34
6.5
5.2
0.68
0.61
%
0.40
33
267
20
166
1.28
0.34
1.5
1.5
—
—
—
0
0
67
639
1.37
0.34
14.3
13.6
23.37
24.29
mg/l
0.08
58
501
7
55
1.30
0.31
1.3
3.4
2.01
2.41
mmol/l
—
7
41
10
76
1.36
0.30
1.0
1.6
—
—
—
0
0
67
642
1.34
0.29
3.4
4.1
4.79
4.73
mmol/l
0.23
60
601
8
62
1.32
0.29
2.3
2.3
1.91
1.79
%
—
8
53
9
75
1.23
0.26
1.1
1.9
—
—
—
0
0
58
607
0.82
0.24
12.6
13.0
40.69
40.04
%
0.25
45
488
7
90
0.76
0.24
1.6
3.8
0.82
0.81
mmol/l
—
7
82
70
677
1.37
0.24
12.5
11.6
—
—
—
0
0
39
360
1.17
0.23
3.6
4.4
6.22
6.67
mmol/l
1.19
39
335
9
111
0.79
0.22
1.8
3.2
2.51
2.45
mmol/l
—
9
99
0
11
0.00
0.21
0.0
3.6
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
64.20
—
0
10
0
13
0.00
0.21
0.0
2.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
6.64
—
0
7
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
66
639
1.23
0.19
3.6
4.1
1.44
1.46
mmol/l
0.15
60
590
71
694
1.30
0.16
14.7
14.6
74.66
76.50
umol/l
0.27
71
694
58
597
0.88
0.12
4.3
5.5
38.62
39.68
mmol/mol
0.38
52
562
23
248
0.90
0.11
4.5
6.1
1.22
1.21
mmol/l
0.12
23
225
5
43
1.17
0.10
1.8
5.4
1.25
1.22
mmol/l
—
5
43
21
195
1.11
0.09
1.6
2.3
—
—
—
0
0
6
54
1.12
0.09
1.3
3.5
—
—
—
0
0
5
63
0.78
0.08
1.8
1.5
—
—
—
0
0
7
63
1.12
0.08
1.3
1.4
—
—
—
0
0
25
241
1.06
0.03
1.4
1.8
86.23
90.23
pmol/l
0.19
13
130
65
658
0.92
0.03
3.8
4.5
3.00
2.82
mmol/l
1.06
59
614
15
143
1.06
0.01
4.5
3.5
1.02
1.02
kg/l
—
5
15
63
624
1.05
0.00
3.4
3.7
1.22
1.30
mmol/l
0.47
56
573
17
172
0.99
0.00
2.2
2.8
—
—
—
0
0
12
115
1.05
0.00
1.5
1.6
—
—
—
0
0
10
95
1.06
0.00
1.2
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
54
0.92
0.00
5.4
4.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
9.3
—
946.33
—
0
6
0
5
0.00
0.00
0.0
8.8
—
0.70
—
0
5
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
4.4
—
51.00
—
0
5
5
49
1.02
0.00
5.2
7.1
—
—
—
0
0
0
6
0.00
0.00
0.0
4.2
—
4.02
—
0
6
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
11.26
—
0
7
0
6
0.00
0.00
0.0
12.7
—
1717.33
—
0
6
72
720
1.00
0.00
20.6
19.0
248.67
249.64
e9/l
0.04
72
704
72
721
0.98
0.00
20.5
18.9
90.06
90.99
fl
0.95
72
711
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
72
721
0.98
0.00
20.6
19.0
4.52
4.53
e12/l
0.08
72
701
0
5
0.00
0.00
0.0
1.8
—
1849.00
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
3.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.3
—
—
—
0
0
72
721
0.98
0.00
20.4
18.9
29.93
30.34
pg
1.21
72
711
72
721
0.98
0.00
20.5
19.1
134.31
136.85
g/l
0.82
72
710
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
8.94
—
0
5
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_OTHER_MOSQUITO_FEVER and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have AB1_OTHER_MOSQUITO_FEVER.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: AB1_OTHER_MOSQUITO_FEVER – Other mosquito-borne viral fevers

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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