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Other congenital malformations of integument

Endpoint Browser

Q17_OTHER_CONGEN_MALFO_INTEG_WIDE

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — Q84
  • Hospital discharge: ICD-10 — Q84
  • Cause of death: ICD-10 — Q84

3 out of 7 registries used, show all original rules.

111

4. Check minimum number of events

None

111

5. Include endpoints

None

111

6. Filter based on genotype QC (FinnGen only)

107

Control definitions (FinnGen only)

Control exclude
Q17_OTHER_CONGEN_MALFO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF13
Parent code in ICD-10
Q8
Name in latin
Aliae malformationes congenitae integumenti communis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 107 55 52
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 62.64 60.18 65.23

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
111
Matched controls
1110
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q84.5
ICD-10 Finland
Enlarged and hypertrophic nails
+∞
83.0
69
*
XCK10
NOMESCO Finland
Photography of fundus of eye
7.1
18.4
34
65
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
4.6
14.5
58
213
E11
ICD-10 Finland
Type 2 diabetes mellitus
5.0
13.0
35
93
L60
ICD-10 Finland
Nail disorders
79.2
12.9
14
*
L84
ICD-10 Finland
Corns and callosities
17.1
12.9
20
14
Z3226
NOMESCO Finland
Physiotherapist
4.5
12.8
44
142
R4110
NOMESCO Finland
Physiotherapy
4.0
11.9
54
211
Z2221
NOMESCO Finland
Medical doctor
4.0
11.6
52
201
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
16.5
10.9
17
12
Q84.9
ICD-10 Finland
Congenital malformation of integument, unspecified
+∞
10.6
10
*
Q84.6
ICD-10 Finland
Other congenital malformations of nails
+∞
10.6
10
*
A28
ICPC
Limited function/disability NOS
4.2
10.4
35
109
ZXE10
NOMESCO Finland
More than one and less than three hours
3.6
10.1
60
274
Q84.8
ICD-10 Finland
Other specified congenital malformations of integument
+∞
9.5
9
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.8
8.8
34
116
L60.3
ICD-10 Finland
Nail dystrophy
97.1
8.5
9
*
B35.1
ICD-10 Finland
Tinea unguium
5.3
8.5
19
42
R5110, ,
SPAT
8.4
8.4
18
25
ZXE00
NOMESCO Finland
One hour or less
3.2
8.2
61
309
I50
ICD-10 Finland
Heart failure
12.1
8.1
14
13
A46
ICD-10 Finland
Erysipelas
3.8
7.9
29
95
Z76.0
ICD-10 Finland
Issue of repeat prescription
3.2
7.2
38
156
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
4.4
7.2
20
53
ZXD10
NOMESCO Finland
Scheduled procedure
2.9
7.0
56
289
WX002
NOMESCO Finland
Sedation and analgesia
3.2
7.0
34
133
Z3231
NOMESCO Finland
Registered nurse
2.9
6.9
47
222
ZXD35
NOMESCO Finland
Usual procedure
8.7
6.9
14
18
ZXA05
NOMESCO Finland
Left side
3.0
6.7
40
176
Z01.7
ICD-10 Finland
Laboratory examination
3.4
6.6
28
100
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
9.0
6.5
13
16
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.4
6.5
28
101
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.0
6.2
36
155
Z71.8
ICD-10 Finland
Other specified counselling
2.8
6.1
45
219

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
31
89
4.45
10.24
1.9
2.1
32.58
31.42
u/l
0.05
24
69
49
214
3.31
8.58
7.3
4.4
—
—
—
0
0
60
313
3.00
7.50
2.7
1.8
87.73
93.02
pmol/l
0.42
35
150
44
203
2.93
6.74
2.7
2.0
3.19
3.08
mg/l
0.08
36
175
35
144
3.09
6.54
3.3
2.7
3.57
2.78
e6/l
0.19
21
77
67
412
2.58
5.54
10.0
7.8
1.19
1.22
mmol/l
2.24
62
348
26
99
3.12
5.46
2.5
1.7
—
—
—
0
0
46
241
2.55
5.28
9.0
7.4
—
—
—
0
0
46
243
2.52
5.17
2.9
2.4
—
—
—
0
0
47
251
2.51
5.16
2.1
2.1
302.33
242.71
u/l
0.23
42
240
62
381
2.42
4.96
4.9
4.2
33.01
35.44
g/l
1.78
56
354
55
324
2.38
4.79
4.5
3.5
108.59
46.15
e6/l
0.42
36
234
50
283
2.40
4.76
3.4
2.9
19.41
256.98
e6/l
0.55
35
224
19
65
3.32
4.71
3.8
2.2
372.37
184.30
ng/l
1.19
19
59
69
453
2.38
4.64
9.2
6.7
0.20
0.20
e9/l
0.03
59
413
69
454
2.37
4.60
7.9
6.3
1.70
1.99
e9/l
1.07
59
419
46
254
2.38
4.60
3.6
2.8
—
—
—
0
0
67
440
2.32
4.43
8.0
6.1
0.61
0.58
e9/l
0.49
57
399
59
369
2.28
4.36
3.4
2.6
165.10
101.88
ug/l
0.94
53
334
46
261
2.30
4.27
3.5
2.8
1.17
0.47
e6/l
0.54
32
201
66
440
2.23
4.09
8.1
6.2
0.04
0.04
e9/l
0.45
56
398
31
152
2.44
3.96
3.3
2.5
2.48
2.45
mmol/l
0.78
26
129
82
604
2.37
3.91
4.0
3.7
—
—
—
0
0
20
79
2.87
3.89
16.2
8.0
—
—
—
0
0
7
8
9.24
3.83
1.1
1.1
—
—
—
0
0
73
517
2.20
3.77
7.6
5.4
7.51
6.60
mmol/l
1.72
66
480
103
878
3.40
3.63
24.9
13.6
30.99
22.69
mg/l
1.50
89
657
35
191
2.22
3.46
2.1
1.9
1.80
1.20
mg/l
0.55
27
156
58
385
2.06
3.44
36.4
13.7
1.40
1.26
inr
0.25
11
120
36
201
2.17
3.35
2.7
3.1
—
—
—
0
0
24
113
2.43
3.31
2.2
2.6
—
—
—
0
0
61
418
2.02
3.26
8.6
9.2
0.00
0.00
e9/l
0.49
51
350
44
269
2.05
3.22
3.5
2.6
—
—
—
0
0
80
608
2.13
3.18
5.1
3.9
—
—
—
0
0
17
69
2.73
3.14
1.6
3.3
0.20
0.21
g/l
0.42
17
62
72
531
2.01
3.05
13.6
9.4
4.52
4.11
e9/l
0.58
64
473
16
66
2.66
2.86
7.7
6.7
24.24
24.83
mmol/l
0.20
16
66
11
34
3.48
2.82
1.8
1.1
—
—
—
0
0
36
215
2.00
2.75
3.2
3.0
376.78
4324.26
umol/l
0.78
27
184
8
19
4.45
2.73
9.0
7.5
—
—
—
0
0
14
56
2.72
2.65
2.7
2.1
—
—
—
0
0
75
578
1.92
2.60
5.7
4.0
—
61.92
—
0
12
10
31
3.44
2.59
2.2
1.7
—
—
—
0
0
22
112
2.20
2.52
14.5
7.0
104.95
104.30
mmol/l
0.38
22
112
41
267
1.85
2.38
3.6
2.8
6.10
7.80
mmol/l
1.24
35
229
22
116
2.12
2.31
1.3
1.6
—
—
—
0
0
17
81
2.30
2.27
1.3
1.5
—
—
—
0
0
57
415
1.77
2.26
7.8
6.7
—
—
—
0
0
13
55
2.54
2.22
20.1
8.7
94.03
93.32
%
0.24
13
55
21
111
2.10
2.19
2.7
2.0
17.02
26.06
%
2.01
16
92
81
658
1.85
2.18
4.0
4.1
19.31
11.12
mm/h
2.59
75
606
25
148
1.89
1.91
1.4
1.7
713.28
1227.98
nmol/l
3.38
18
119
98
861
2.18
1.91
4.9
4.8
2.58
2.67
mmol/l
0.44
92
788
8
28
3.00
1.90
1.6
2.9
74.85
31.23
mg/l
—
8
23
8
28
3.00
1.90
1.6
2.9
33.49
37.03
mg/l
—
8
23
104
947
2.56
1.86
18.1
12.3
—
—
—
0
0
36
241
1.73
1.85
3.9
3.0
1723.18
57.53
mg/l
0.52
23
158
5
13
3.97
1.73
2.6
1.5
—
—
—
0
0
94
822
1.94
1.73
5.1
4.5
1.90
1.89
mu/l
0.02
89
738
12
56
2.28
1.68
7.3
12.6
—
—
—
0
0
34
230
1.69
1.67
1.3
1.4
—
—
—
0
0
95
838
1.93
1.63
3.7
4.3
1.38
1.45
mmol/l
1.02
83
767
7
26
2.80
1.61
1.1
1.2
—
—
—
0
0
29
190
1.71
1.59
2.4
2.7
653.62
553.17
mosm/kgh2o
0.81
21
161
42
304
1.61
1.58
3.1
3.1
2.34
2.36
mmol/l
0.34
37
267
95
843
1.88
1.53
3.9
4.4
4.42
4.55
mmol/l
0.62
84
779
6
21
2.96
1.52
1.0
1.1
—
—
—
0
0
16
88
1.96
1.51
1.3
1.1
—
—
—
0
0
22
135
1.79
1.50
1.5
1.6
—
—
—
0
0
29
196
1.65
1.41
1.5
1.5
2.16
2.54
g/l
0.46
13
104
9
42
2.24
1.37
17.8
22.3
—
—
—
0
0
15
244
0.55
1.30
3.3
3.5
0.00
0.00
estimate
—
5
90
21
309
0.60
1.25
2.1
2.9
—
—
—
0
0
5
19
2.71
1.23
1.2
4.4
42.40
47.42
umol/l
—
5
19
25
169
1.62
1.21
2.3
2.9
1.59
0.75
ug/l
0.30
12
113
8
38
2.19
1.21
1.4
1.2
—
—
—
0
0
8
40
2.08
1.14
1.0
1.1
—
—
—
0
0
19
122
1.67
1.11
1.3
1.2
—
—
—
0
0
34
252
1.50
1.11
5.6
3.5
31.34
9.33
mg/mmol
0.55
21
158
90
813
1.57
1.03
3.5
3.9
1.29
1.27
mmol/l
0.12
77
739
5
101
0.47
0.95
1.8
1.6
—
—
—
0
0
17
111
1.63
0.94
1.3
1.6
—
—
—
0
0
18
258
0.64
0.93
2.7
3.3
—
—
—
0
0
55
459
1.39
0.93
2.7
3.4
0.00
0.00
estimate
—
6
87
6
29
2.13
0.91
1.0
1.6
—
—
—
0
0
42
336
1.40
0.91
2.4
2.0
—
—
—
0
0
22
155
1.52
0.90
1.2
1.3
15.54
30.27
iu/ml
—
8
58
54
454
1.37
0.86
4.4
4.7
0.00
0.00
estimate
—
6
93
26
193
1.45
0.83
2.3
2.4
10.42
4.71
e6/l
0.36
21
176
91
840
1.46
0.77
4.8
4.5
6.33
5.93
mmol/l
1.17
84
758
5
26
1.97
0.71
4.2
1.7
0.19
0.22
g/l
—
5
26
5
27
1.89
0.69
1.8
3.9
—
—
—
0
0
5
27
1.89
0.69
4.6
1.6
1.09
1.14
g/l
—
5
27
12
78
1.60
0.69
2.1
1.7
—
—
—
0
0
11
70
1.63
0.68
1.1
1.2
—
—
—
0
0
5
28
1.82
0.67
1.2
3.1
—
—
—
0
0
52
449
1.30
0.64
2.8
3.3
0.00
0.00
estimate
—
6
103
0
21
0.00
0.60
0.0
1.6
—
—
—
0
0
21
160
1.39
0.59
2.0
1.9
—
—
—
0
0
5
87
0.55
0.59
4.2
3.3
—
—
—
0
0
9
65
1.42
0.52
1.1
1.5
—
—
—
0
0
72
660
1.26
0.50
4.2
3.9
14.54
14.79
pmol/l
0.37
66
593
20
249
0.76
0.47
2.2
3.9
—
—
—
0
0
38
330
1.23
0.42
2.5
4.1
38.99
40.57
ng/l
0.03
17
236
0
15
0.00
0.41
0.0
2.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.6
—
106.07
—
0
15
0
15
0.00
0.41
0.0
2.6
—
4.02
—
0
15
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
2.5
—
—
—
0
0
7
53
1.34
0.31
3.1
3.4
4.33
4.46
pmol/l
—
7
43
32
282
1.19
0.30
3.3
5.2
10.26
2.16
ug/l
0.41
27
245
5
40
1.26
0.23
15.0
4.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
4.9
—
—
—
0
0
0
12
0.00
0.21
0.0
2.6
—
3.67
—
0
12
6
49
1.24
0.20
1.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
251.14
—
0
14
6
50
1.21
0.20
1.0
1.3
—
—
—
0
0
11
91
1.23
0.18
1.6
1.3
—
—
—
0
0
5
46
1.09
0.10
1.8
2.7
0.32
0.10
e6/l
—
5
46
6
58
1.04
0.08
1.5
1.3
—
—
—
0
0
5
63
0.78
0.08
2.4
3.3
—
—
—
0
0
6
70
0.85
0.08
2.8
3.7
1.21
1.22
mmol/l
—
6
63
8
73
1.10
0.08
1.4
1.8
—
—
—
0
0
11
101
1.10
0.04
1.4
1.2
—
—
—
0
0
6
69
0.86
-0.00
2.2
4.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
29301.00
—
0
5
7
75
0.93
-0.00
1.4
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
33.00
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
0.82
—
0
7
0
5
0.00
-0.00
0.0
5.6
—
1.70
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
8.63
—
0
6
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
1.57
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
177.00
—
0
5
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
13.8
—
9.27
—
0
6
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
5.89
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: Q17_OTHER_CONGEN_MALFO_INTEG_WIDE – Other congenital malformations of integument

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).