Oesophagitis, drug-induced

K11_OESITIS_ADVERSE

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ATC codes for adverse effects of Drugs — ANY Hospital discharge: ICD-10 — K20 1 out of 7 registries used, show all original rules.	82
4. Check minimum number of events None	82
5. Include endpoints None	82
6. Filter based on genotype QC (FinnGen only)	82

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: C
First used in FinnGen datafreeze: DF5
Parent code in ICD-10: K00-K14
Name in latin: Oesophagitis

NAME	K11_OESITIS_ADVERSE
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC	ANY
HD_ICD_10	K20
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Oesophagitis, drug-induced based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (not available in FinRegistry).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	82	43	39
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	50.22	49.21	51.33

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
78: Matched controls
781

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

K20

ICD-10 Finland

Oesophagitis

+∞

102.5

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

7.5

15.4

179

K21.0

ICD-10 Finland

Gastro-oesophageal reflux disease with oesophagitis

9.0

13.7

UJD02

NOMESCO Finland

Gastroscopy

17.9

10.5

A02BC01

ATC

omeprazole; systemic

4.9

9.9

156

A02BA02

ATC

ranitidine; systemic

4.5

7.6

100

A02BC02

ATC

pantoprazole; systemic

4.5

7.1

411

A03FA02

ATC

cisapride; oral, rectal

6.7

6.4

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

3.4

6.1

177

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768797) Stomach Pathology biopsy report

3.72

6.52

1.8

1.2

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

273

2.00

2.44

3.3

2.8

158.78

120.23

ug/l

0.42

251

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.41

2.26

2.8

1.6

—

(4034850)

3.43

2.16

3.4

8.1

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

4.23

2.08

1.0

1.3

—

(1002224) Polysomnography panel

3.05

1.92

1.3

1.1

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.71

1.92

1.4

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

3.51

1.78

1.2

1.1

—

(3026493) Urate [Moles/volume] in Serum or Plasma

188

1.84

1.76

2.3

2.5

349.00

14752.02

umol/l

1.99

161

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

496

1.90

1.73

4.4

3.9

14.90

14.87

pmol/l

0.03

438

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

123

1.95

1.72

1.5

1.3

31.22

10.90

u/ml

—

(3012516) Albumin [Mass/volume] in Urine

207

1.80

1.70

3.2

1692.70

70.94

mg/l

0.47

139

(3008898) HLA-B27 [Presence]

3.32

1.69

1.0

1.1

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

2.23

1.65

2.2

1.5

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.23

1.65

3.0

1.6

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

2.66

1.64

1.3

1.2

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

2.66

1.64

19.6

6.8

24.54

24.39

mmol/l

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.85

1.62

1.0

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

3.48

1.54

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

3.48

1.54

1.2

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

3.48

1.54

1.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

287

1.68

1.49

2.4

1.9

97.70

97.10

pmol/l

0.02

144

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.64

1.49

1.3

—

(3045414) Leukocytes [Presence] in Urine

2.54

1.42

1.6

1.5

—

(3001604) Monocytes [#/volume] in Blood

337

1.66

1.42

7.6

5.6

0.55

0.58

e9/l

0.57

289

(3006315) Basophils [#/volume] in Blood

337

1.66

1.42

7.6

5.7

0.04

e9/l

0.13

291

(3002030) Lymphocytes/100 leukocytes in Blood

329

1.65

1.39

7.9

5.9

27.03

26.51

0.09

301

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

2.61

1.33

1.8

1.0

0.30

0.25

g/l

—

(42870588) Differential panel, method unspecified - Blood

220

1.66

1.33

9.9

5.6

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

151

1.73

1.30

2.5

3.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.87

1.29

1.3

1.5

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.99

1.28

2.5

3.85

12.41

umol/l

0.99

(3009508) Creatinine [Moles/volume] in Urine

213

1.64

1.28

3.1

7.10

7.64

mmol/l

0.24

179

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

2.51

1.27

1.8

1.1

1.42

1.18

g/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.85

1.25

2.9

1.8

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.73

1.23

1.0

1.2

—

(3018418) pH of Serum or Plasma

206

1.63

1.22

6.1

3.8

7.39

7.40

—

(3000492) Spirometry study

2.00

1.13

1.5

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.37

1.13

2.9

2.2

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.05

1.12

1.6

1.5

—

(3000991) Gas panel - Venous blood

2.05

1.11

17.7

7.3

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

133

1.67

1.07

1.6

1.3

13.09

43.91

iu/ml

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.01

1.06

1.1

1.2

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

100

1.75

1.06

1.9

1.8

—

(40758558) Short blood count panel - Blood

168

1.61

1.06

14.8

6.8

—

(3020682) Albumin/Creatinine [Ratio] in Urine

223

1.54

1.03

3.6

4.0

6.39

11.30

mg/mmol

0.53

149

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

327

1.51

1.01

11.2

6.0

1.20

1.21

mmol/l

0.39

271

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

144

1.62

1.00

3.1

0.55

0.77

ug/l

1.44

103

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.23

0.93

1.2

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.01

0.86

1.0

1.1

—

(3029937) Albumin [Presence] in Urine by Test strip

194

1.50

0.86

3.4

3.7

0.09

0.00

estimate

0.47

(3035350) Ketones [Presence] in Urine by Test strip

345

1.45

0.86

3.1

3.6

0.00

estimate

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

259

1.46

0.85

3.5

3.1

—

(3009261) Glucose [Presence] in Urine by Test strip

346

1.44

0.84

3.0

3.7

0.00

estimate

0.00

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.94

0.83

22.5

5.5

—

(3025941) Bacteria identified in Stool by Culture

1.94

0.83

1.2

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

1.94

0.83

1.2

2.1

1.94

1.64

g/l

—

(3021601) Nitrite [Presence] in Urine by Test strip

347

1.43

0.82

3.9

5.1

0.00

estimate

0.00

(40761536) Microorganisms panel - Urine sediment

1.74

0.80

4.6

3.5

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

2.25

0.77

1.0

0.00

g/l

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

2.25

0.77

1.0

0.00

g/l

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

370

1.41

0.76

5.8

10.11

11.03

umol/l

0.59

345

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

2.06

0.74

1.0

0.00

g/l

—

(3000494) Fungus identified in Specimen by Culture

1.65

0.73

1.7

1.5

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.52

0.72

1.4

1.3

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

1.91

0.69

1.0

0.00

0.04

g/l

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.66

0.69

2.1

1.8

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.69

0.69

1.6

1.8

—

(3042936) Bacteria identified in Isolate by Culture

1.55

0.67

2.2

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

114

1.50

0.65

3.3

2.6

2.49

2.30

g/l

0.75

101

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.71

0.62

4.6

3.3

0.38

0.69

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

143

1.43

0.59

5.2

2.2

—

(3005322) IgE [Units/volume] in Serum or Plasma

1.67

0.57

1.5

1.2

90.67

255.03

u/ml

—

(4035726)

1.56

0.57

1.6

1.5

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.56

0.57

1.8

2.4

408.44

358.00

nmol/l

—

(3030467) Casts [#/volume] in Urine by Automated count

209

1.36

0.56

3.2

3.0

0.02

0.42

e6/l

3.63

151

(3020630) Protein [Mass/volume] in Serum or Plasma

1.51

0.55

1.2

1.6

66.98

67.16

g/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

286

1.32

0.54

2.9

4.1

13.35

29.42

ng/l

4.40

205

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.54

0.54

2.3

1.6

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

192

1.35

0.53

4.2

4.4

21.21

19.82

0.23

102

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

111

1.43

0.51

2.9

3.0

2.29

2.67

e6/l

—

(3022948) Iron [Moles/volume] in Serum or Plasma

122

1.39

0.47

3.3

2.5

11.99

13.87

umol/l

0.70

110

(3044889) 12 lead EKG panel

491

1.29

0.46

4.1

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

0.62

0.45

5.8

5.1

34.50

33.30

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

123

1.37

0.45

2.9

2.6

0.20

1.59

e6/l

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.49

0.44

6.6

4.2

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.60

0.43

4.6

3.2

1.00

1.15

—

(3007164) IgA [Mass/volume] in Serum or Plasma

133

1.35

0.43

1.5

1.3

1.90

2.74

g/l

—

(3012544) pH of Venous blood

1.39

0.42

3.6

4.4

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.41

0.0

1.2

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.41

0.0

1.3

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.41

0.0

4.1

—

7.07

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.41

0.0

3.9

—

1.44

—

(3026008) Bacteria identified in Urine by Culture

209

1.28

0.40

2.9

3.0

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.40

0.0

3.9

—

31.95

—

(3023368) Bacteria identified in Blood by Culture

191

1.28

0.39

6.5

3.8

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.41

0.39

4.6

3.7

122.80

125.83

g/l

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

698

1.42

0.38

23.3

16.8

4.02

3.99

mmol/l

0.42

680

(1761868) Lipid panel - Serum or Plasma

230

0.77

0.38

3.1

3.2

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.50

0.37

2.2

1.6

0.46

1.17

g/l

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.43

0.36

25.0

5.9

0.42

0.64

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.43

0.36

24.2

5.9

0.90

1.25

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

270

1.24

0.36

3.4

3.9

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.67

0.35

4.7

7.2

—

(3002582) Erythrocytes [#/volume] in Urine

223

1.24

0.34

3.2

23.38

349.39

e6/l

0.55

164

(3022145) Colonoscopy Study observation

1.38

0.34

1.2

1.3

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.41

0.32

2.4

2.6

137.00

247.79

ng/l

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.38

0.32

2.4

1.6

—

(40761511) CBC panel - Blood by Automated count

690

0.78

0.32

16.6

14.4

—

(36304419) Bacteria [Presence] in Urine

196

1.24

0.32

3.4

2.8

—

(40760892) CBC W Ordered Manual Differential panel - Blood

153

1.23

0.25

2.7

4.2

—

(3000330) Specific gravity of Urine by Test strip

1.37

0.24

2.2

4.5

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

696

1.28

0.23

23.0

16.7

139.68

139.61

mmol/l

0.09

679

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

184

1.19

0.22

1.6

1.51

1.35

mmol/l

0.32

153

(3020564) Creatinine [Moles/volume] in Serum or Plasma

710

1.26

0.21

21.3

17.4

91.78

79.33

umol/l

0.53

710

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.21

0.0

1.5

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

0.21

0.0

1.5

—

6.73

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

0.21

0.0

1.8

—

33.11

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.1

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

0.21

0.0

1.4

—

200.50

—

(4146454)

0.00

0.21

0.0

3.5

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.21

0.0

1.1

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

3.7

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

3.7

—

106.33

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

3.7

—

4.00

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.20

0.0

1.1

—

6.67

—

(3025159) Blasts/100 leukocytes in Blood

1.19

0.20

2.3

4.4

—

0.07

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.17

0.19

1.2

1.3

—

(3002179) Metamyelocytes/100 leukocytes in Blood

1.17

0.19

2.5

4.0

—

0.54

—

(40761535) Cells panel - Urine sediment

1.23

0.19

2.7

3.2

—

(3037467) Urinalysis macro (dipstick) panel - Urine

465

1.13

0.17

4.9

4.3

—

(3013512) EKG study

212

0.86

0.16

4.2

4.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

312

0.89

0.14

8.0

3.6

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

663

1.15

0.12

20.3

14.5

20.56

23.06

mg/l

0.36

529

(3032080) INR in Blood by Coagulation assay

291

1.10

0.12

14.1

8.4

1.10

1.25

inr

0.83

(3021440) Promyelocytes/100 leukocytes in Blood

1.14

0.09

2.5

4.3

—

0.25

—

(36660697) Celiac disease serology panel - Serum

1.12

0.09

1.2

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

707

1.15

0.09

13.3

10.9

30.83

25.28

u/l

0.71

680

(3017181) Myelocytes/100 leukocytes in Blood

1.04

0.08

2.5

4.1

—

0.84

—

(3003396) Base excess in Arterial blood by calculation

1.06

0.07

19.9

5.2

-0.05

1.03

mmol/l

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.09

0.07

3.7

2.4

1.50

1.80

—

(3000963) Hemoglobin [Mass/volume] in Blood

735

0.94

0.07

30.4

21.8

136.30

135.20

g/l

0.28

723

(3035941) MCH [Entitic mass]

735

0.94

0.07

30.0

21.5

30.45

30.41

0.08

723

(3024731) MCV [Entitic volume]

734

0.95

0.07

30.1

21.6

91.45

91.38

0.05

722

(3044640) Blood type and Crossmatch panel - Blood

198

1.08

0.06

5.0

2.2

—

(3031040) Bacteria [#/volume] in Urine by Automated count

449

1.06

0.04

5.8

4.3

—

78.38

—

(3003694) ABO and Rh group [Type] in Blood

171

1.07

0.03

1.8

1.4

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

641

1.07

0.03

19.0

14.5

77.17

77.87

ml/min/173m2

0.09

522

(3018095) Leukocytes [#/volume] in Urine

261

1.05

0.03

3.8

3.7

78.30

74.05

e6/l

0.02

180

(3041096) Erythrocytes [Presence] in Urine by Automated

198

0.95

0.02

3.6

3.7

—

(40768804) Tissue Pathology biopsy report

279

1.01

0.00

2.1

2.2

—

(3009542) Hematocrit [Volume Fraction] of Blood

583

0.98

0.00

28.7

15.7

38.18

39.08

0.22

395

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

365

1.02

0.00

3.1

2.7

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

251

0.99

0.00

5.1

2.90

2.07

ug/l

0.57

220

(3019225) pH of Specimen

0.98

0.00

9.7

3.7

—

(3035880) pH of Pleural fluid

0.00

0.0

1.2

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

2.2

—

14.39

—

(3004451) EKG impression Narrative

0.00

0.0

1.4

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.1

—

(3020876) Protein [Mass/time] in 24 hour Urine

0.00

0.0

2.2

—

(3012441) Differential panel - Pleural fluid

0.00

0.0

1.9

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.7

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.4

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.0

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.7

—

(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate

0.00

0.0

10.4

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.0

1.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.0

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

0.0

2.4

—

3.34

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

2.2

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.7

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

0.0

1.0

—

(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture

0.00

0.0

1.0

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.7

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.0

1.1

—

(3011436) Histone Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.7

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.0

2.0

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.1

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

29.60

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.0

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

0.0

1.7

—

(3027456) Digoxin [Moles/volume] in Serum or Plasma

0.00

0.0

3.3

—

0.75

—

(3002256) Pathology report gross observation

0.89

0.00

1.7

1.2

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

2.5

—

128.25

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

0.79

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.8

—

(3044941) Cell count panel - Synovial fluid

0.00

0.0

1.3

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.3

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

3.7

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.0

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.0

2.2

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.7

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

12.22

—

(4268621)

0.00

0.0

1.8

—

(3045788) Cell count panel - Pleural fluid

0.00

0.0

1.4

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

(3020491) Glucose [Moles/volume] in Blood

0.00

0.0

2.0

—

7.46

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.4

—

(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma

0.00

0.0

2.0

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.8

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

This endpoint is excluded (not available in FinRegistry).

Relationships between endpoints

↥

Index endpoint: K11_OESITIS_ADVERSE – Oesophagitis, drug-induced

GWS hits: -

This endpoint is excluded (not available in FinRegistry).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Oesophagitis, drug-induced

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Oesophagitis, drug-induced (K11_OESITIS_ADVERSE)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints