No definition available.
Personality and behavioural disorders due to brain disease, damage and dysfunction
EFO MESH Endpoint Browser PheWeb
F5_PERSBEHORG
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
568 |
4. Check minimum number of eventsNone |
568 |
5. Include endpointsNone |
568 |
6. Filter based on genotype QC (FinnGen only) |
549 |
Control definitions (FinnGen only)
- Control exclude
- F5_ORGANIC
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- F04-F09
- Name in latin
- Perturbationes personae et modi se gerendi a morbo, laesione sive dysfunctione cerebri inductae
Similar endpoints
↥List of similar endpoints to
Personality and behavioural disorders due to brain disease, damage and dysfunction
based on the number of shared cases.
Similar with more cases:
- Organic, including symptomatic, mental disorders
- Psychiatric diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7855 | 2589 | 5124 |
| Only index persons | 5216 | 1732 | 3484 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.07 | 0.14 |
| Only index persons | 0.11 | 0.06 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 53.93 | 56.68 | 52.32 |
| Only index persons | 49.75 | 51.79 | 48.73 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 549 | 194 | 355 |
| Unadjusted period prevalence (%) | 0.13 | 0.07 | 0.16 |
| Median age at first event (years) | 51.30 | 46.96 | 53.66 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 567
- Matched controls
- 5663
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
T90.5
ICD-10 Finland
Sequelae of intracranial injury
64.7
196.5
110
21
F07.9
ICD-10 Finland
Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
+∞
185.9
168
*
F07.2
ICD-10 Finland
Postconcussional syndrome
+∞
168.3
153
*
N03AG01
ATC
valproic acid; systemic, rectal
16.5
167.2
159
131
N05AX08
ATC
risperidone; systemic
14.3
164.8
174
170
F07.8
ICD-10 Finland
Other organic personality and behavioural disorders due to brain disease, damage and dysfunction
+∞
119.0
110
*
F03
ICD-10 Finland
Unspecified dementia
66.5
117.4
65
11
S06.2
ICD-10 Finland
Diffuse brain injury
39.1
110.6
69
20
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
12.0
109.3
122
126
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
9.7
103.9
140
186
N05AH03
ATC
olanzapine; systemic
10.5
102.6
127
151
G40.9
ICD-10 Finland
Epilepsy, unspecified
15.7
102.1
94
71
S06.3
ICD-10 Finland
Focal brain injury
28.7
93.2
64
25
N05AD01
ATC
haloperidol; systemic
16.5
89.4
79
55
F07.0
ICD-10 Finland
Organic personality disorder
+∞
83.4
78
*
N05AH04
ATC
quetiapine; oral
5.7
82.9
207
515
N06AB04
ATC
citalopram; systemic
5.0
73.4
223
647
N05AA02
ATC
levomepromazine; systemic
9.7
70.4
89
107
F32.9
ICD-10 Finland
Depressive episode, unspecified
5.9
68.2
150
328
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
16.9
67.4
58
38
N03AF02
ATC
oxcarbazepine; oral
12.0
66.6
71
67
F29
ICD-10 Finland
Unspecified nonorganic psychosis
10.1
62.4
75
84
XA800
NOMESCO Finland
Neuropsychological investigation
10.0
61.8
75
85
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
23.2
55.5
41
19
N03AF01
ATC
carbamazepine; oral, rectal
7.2
55.5
90
144
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
13.8
54.4
52
41
T36
ICD-10 Finland
Poisoning by systemic antibiotics
8.9
53.5
71
90
N05BA01
ATC
diazepam; systemic, rectal
4.6
53.1
157
434
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
12.6
52.2
53
46
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
10.1
52.2
62
68
R56.8
ICD-10 Finland
Other and unspecified convulsions
7.4
52.0
82
127
N03AX14
ATC
levetiracetam; systemic
12.1
51.7
54
49
R41.0
ICD-10 Finland
Disorientation, unspecified
14.5
51.6
48
36
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
6.2
51.6
98
184
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.5
46.3
102
219
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
9.5
43.8
54
62
N05CD07
ATC
temazepam; oral
4.3
43.1
135
385
F10.20
ICD-10 Finland
Alcohol dependence currently independent
11.0
42.7
47
46
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
5.3
42.5
96
210
N05BA06
ATC
lorazepam; systemic, sublingual
6.4
42.2
75
131
N03AB02
ATC
phenytoin; systemic
16.6
42.0
36
23
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
5.9
41.9
83
161
A28
ICPC
Limited function/disability NOS
3.9
40.5
148
470
N05BA04
ATC
oxazepam; oral
3.4
39.9
209
837
F06.9
ICD-10 Finland
Unspecified mental disorder due to brain damage and dysfunction and to physical disease
+∞
39.0
37
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.6
38.6
162
563
N03AX09
ATC
lamotrigine; oral
6.6
38.5
66
111
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
12.2
38.1
39
34
Z2445
NOMESCO Finland
Psychologist
7.2
37.7
59
90
AA1AD
NOMESCO Finland
CT of head and brain
3.2
37.4
221
946
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
14.4
36.7
34
25
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
4.9
36.1
89
209
F05.9
ICD-10 Finland
Delirium, unspecified
191.6
35.2
36
*
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
33.7
32
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.0
33.5
234
1088
N05AF03
ATC
chlorprothixene; systemic
8.6
33.2
44
55
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.5
32.0
87
220
N06AX11
ATC
mirtazapine; oral
2.9
31.9
240
1155
F07.1
ICD-10 Finland
Postencephalitic syndrome
+∞
30.5
29
*
N04AA02
ATC
biperiden; systemic
10.9
29.1
32
31
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
7.0
28.9
46
71
W19
ICD-10 Finland
Unspecified fall
3.9
27.8
92
268
A06AD11
ATC
lactulose; oral
3.3
27.7
129
470
S06.0
ICD-10 Finland
Concussion
3.6
27.4
102
322
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
10.5
26.7
30
30
N06DA03
ATC
rivastigmine; oral, transdermal
63.1
26.2
30
5
N03AE01
ATC
clonazepam; systemic
4.9
25.6
59
130
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
25.4
202
978
N06AX16
ATC
venlafaxine; oral
3.3
25.4
112
393
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
5.6
25.3
50
96
N06DX01
ATC
memantine; oral
31.7
25.3
33
11
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
4.0
25.1
79
222
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
24.8
107
370
N05BE01
ATC
buspirone; oral
6.2
24.8
44
76
F10.25
ICD-10 Finland
Alcohol dependence continuous use
8.6
24.6
32
39
N06DA02
ATC
donepezil; oral
28.1
23.8
32
12
G30.1
ICD-10 Finland
Alzheimer disease with late onset
22.5
23.7
34
16
N05CF01
ATC
zopiclone; oral
2.5
23.7
233
1241
N07BB01
ATC
disulfiram; oral
4.8
23.4
56
127
S01.0
ICD-10 Finland
Open wound of scalp
3.8
23.3
78
228
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.9
23.1
53
116
N06AB03
ATC
fluoxetine; oral
3.2
22.8
106
383
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
9.7
22.8
27
29
F05.8
ICD-10 Finland
Other delirium
124.9
22.7
24
*
F60.9
ICD-10 Finland
Personality disorder, unspecified
18.9
22.4
34
19
N05AX12
ATC
aripiprazole; systemic
5.5
22.3
45
88
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
26.3
21.9
30
12
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
21.6
133
561
N05BA09
ATC
clobazam; oral
27.7
21.5
29
11
N06AB06
ATC
sertraline; oral
3.3
21.4
89
300
T74.1
ICD-10 Finland
Physical abuse
7.9
21.4
30
40
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.6
21.1
76
233
3101A
ICD-9 Finland
Specific nonpsychotic mental disorders following organic brain damage, Organic personality syndrome
+∞
21.0
20
*
F01.9
ICD-10 Finland
Vascular dementia, unspecified
+∞
21.0
20
*
Z2446
NOMESCO Finland
Social worker
3.8
20.8
69
200
N06AX03
ATC
mianserin; oral
4.7
20.5
49
111
183
Kela drug reimbursment
Lamotrigin and topiramate
18.1
20.2
31
18
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.6
20.1
72
220
N05AB03
ATC
perphenazine; systemic, rectal
5.5
20.1
40
77
X59
ICD-10 Finland
Exposure to unspecified factor
2.6
20.0
141
634
L28
ICPC
Limited function/disability (L)
2.8
19.7
119
494
F06.7
ICD-10 Finland
Mild cognitive disorder
25.6
19.7
27
11
N06AX21
ATC
duloxetine; oral
3.2
19.7
86
298
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
6.6
19.4
32
51
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
3.5
19.2
73
232
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.3
19.1
51
126
N05AH02
ATC
clozapine; systemic
7.0
18.8
29
43
N05AC02
ATC
thioridazine; oral
8.1
18.4
25
32
N06AB10
ATC
escitalopram; oral
2.5
18.2
135
620
N05BA02
ATC
chlordiazepoxide; systemic
5.5
17.7
35
67
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
6.8
17.6
28
43
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.6
17.5
116
503
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
6.9
17.1
27
41
85190
ICD-8 Finland
Cerebral laceration and contusion, Late effect
92.7
16.6
18
*
AAD05
NOMESCO Finland
Evacuation of acute subdural haematoma
28.5
16.6
22
8
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.1
16.2
72
251
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
4.6
16.1
39
89
N05AN01
ATC
lithium; oral
5.9
16.0
29
51
P20
ICPC
Memory disturbance
3.1
15.7
73
261
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
4.3
15.7
42
104
F10.24
ICD-10 Finland
Alcohol depence active use
6.7
15.5
25
39
R53
ICD-10 Finland
Malaise and fatigue
2.3
15.4
155
809
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.7
15.3
95
397
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
3.2
15.1
65
222
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.8
15.1
48
135
F22.0
ICD-10 Finland
Delusional disorder
13.7
14.8
25
19
F10.09
ICD-10 Finland
Alcohol intoxication UNS
5.5
14.8
29
55
N03AX18
ATC
lacosamide; systemic
21.7
14.7
21
10
N05CD02
ATC
nitrazepam; oral
6.5
14.6
24
38
F06.32
ICD-10 Finland
Organic depression
+∞
14.6
14
*
F06.2
ICD-10 Finland
Organic delusional [schizophrenia-like] disorder
+∞
14.6
14
*
29350
ICD-8 Finland
Psychosis associated with other cerebral condition, Brain trauma
+∞
14.6
14
*
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.3
14.6
38
92
F06.8
ICD-10 Finland
Other specified mental disorders due to brain damage and dysfunction and to physical disease
153.6
14.5
15
*
S06.4
ICD-10 Finland
Epidural haemorrhage
153.6
14.5
15
*
N05AD03
ATC
melperone; systemic
11.8
14.4
26
23
F20.9
ICD-10 Finland
Schizophrenia, unspecified
5.9
14.2
26
46
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
43.6
14.2
17
*
P29
ICPC
Psychological sympt/compl other
3.5
14.0
51
157
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.9
14.0
71
267
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.7
13.9
45
128
N03AX16
ATC
[U] pregabalin
2.2
13.8
147
780
ZXD35
NOMESCO Finland
Usual procedure
4.5
13.7
34
79
N05AF05
ATC
zuclopenthixol; systemic
15.2
13.7
22
15
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
13.7
61
213
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
76.9
13.6
15
*
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
143.1
13.5
14
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.6
13.5
83
345
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
26.4
13.4
18
7
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
21.8
13.4
19
9
G40
ICD-10 Finland
Epilepsy
14.2
13.3
22
16
ZXD05
NOMESCO Finland
Urgent procedure
2.0
13.2
191
1135
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
15.5
13.2
21
14
TAB00
NOMESCO Finland
Lumbar puncture
4.1
13.2
37
95
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.6
12.8
78
322
N06AX05
ATC
trazodone; oral
4.8
12.7
29
63
R4120
NOMESCO Finland
Occupational therapy
3.3
12.7
51
167
F99
ICD-10 Finland
Mental disorder, not otherwise specified
6.1
12.7
22
37
G41.9
ICD-10 Finland
Status epilepticus, unspecified
32.8
12.6
16
5
N28
ICPC
Limited function/disability (N)
11.3
12.6
23
21
S06.9
ICD-10 Finland
Intracranial injury, unspecified
17.8
12.6
19
11
EBA15
NOMESCO Finland
Extraction of multiple teeth
4.2
12.5
34
85
N03AX11
ATC
topiramate; oral
5.2
12.5
26
52
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
9.3
12.3
25
28
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
14.7
12.3
20
14
OAB43, ,
SPAT
0.2
12.1
24
872
IGY02
NOMESCO Finland
Psychiatric monitoring contact
4.8
12.0
27
58
S72.0
ICD-10 Finland
Fracture of neck of femur
4.1
11.9
33
84
SPAT1229
SPAT
Assessment of need for aid
3.1
11.9
51
174
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
15.1
11.9
19
13
R40.2
ICD-10 Finland
Coma, unspecified
10.8
11.8
22
21
R42
ICD-10 Finland
Dizziness and giddiness
2.1
11.8
135
732
N06AG02
ATC
moclobemide; oral
3.8
11.8
37
103
W17
ICD-10 Finland
Other fall from one level to another
3.9
11.7
35
94
85100
ICD-8 Finland
Cerebral laceration and contusion, Without mention of open intracranial wound
23.4
11.6
16
7
F05.1
ICD-10 Finland
Delirium superimposed on dementia
+∞
11.5
11
*
W10
ICD-10 Finland
Fall on and from stairs and steps
3.3
11.5
44
140
WX730
NOMESCO Finland
Conventional respirator
9.9
11.3
22
23
P99
ICPC
Psychological disorders other
4.6
11.3
27
61
N05AB01
ATC
dixyrazine; systemic
9.5
11.1
22
24
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
10.3
11.1
21
21
N06AA09
ATC
amitriptyline; systemic
2.7
10.9
63
253
R51.80
ICD-10 Finland
Headache
2.2
10.9
97
476
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
4.9
10.8
24
51
N88
ICPC
Epilepsy
28.6
10.8
14
5
WX892
NOMESCO Finland
Monitored bed care
2.7
10.7
59
231
K08.3
ICD-10 Finland
Retained dental root
2.8
10.5
55
210
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
7.9
10.5
23
30
N06DA04
ATC
galantamine; oral
111.9
10.4
11
*
F06.39
ICD-10 Finland
Organic mood syndrome UNS
+∞
10.4
10
*
F02.89*G40.9
ICD-10 Finland
Dementia in epilepsy
+∞
10.4
10
*
F06.0
ICD-10 Finland
Organic hallucinosis
+∞
10.4
10
*
29399
ICD-8 Finland
Psychosis associated with other cerebral condition, Other and unspecified cerebral condition
+∞
10.4
10
*
9070A
ICD-9 Finland
Late effects of injuries to the nervous system, Late effect of intracranial injury without mention of skull fracture
+∞
10.4
10
*
Z3226
NOMESCO Finland
Physiotherapist
2.1
10.4
114
607
34599
ICD-8 Finland
Epilepsy, Other and unspecified
19.2
10.3
15
8
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
13.4
10.2
17
13
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.5
10.2
70
306
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
9.4
10.1
20
22
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
14.9
10.0
16
11
G31.0
ICD-10 Finland
Circumscribed brain atrophy
40.8
10.0
12
*
F39
ICD-10 Finland
Unspecified mood [affective] disorder
7.8
10.0
22
29
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
9.7
86
420
S72.1
ICD-10 Finland
Pertrochanteric fracture
5.4
9.7
19
36
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.7
9.7
54
213
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
9.3
9.6
19
21
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
3.5
9.6
33
98
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
5.3
9.4
19
37
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
4.5
9.4
23
53
F05.0
ICD-10 Finland
Delirium not superimposed on dementia, so described
+∞
9.4
9
*
AAK00
NOMESCO Finland
Cranioplasty
+∞
9.4
9
*
R41.3
ICD-10 Finland
Other amnesia
5.0
9.4
20
41
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.7
9.3
30
85
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
9.3
94
483
EBA00
NOMESCO Finland
Extraction of tooth
1.8
9.2
195
1287
ZY010
NOMESCO Finland
Hospital outpatient
3.0
9.1
40
138
N06AB08
ATC
fluvoxamine; oral
4.1
9.1
25
63
R11
ICD-10 Finland
Nausea and vomiting
2.5
9.1
57
238
G72.8
ICD-10 Finland
Other specified myopathies
4.9
9.1
20
42
S02.20
ICD-10 Finland
Fracture of nasal bones, closed
4.9
9.1
20
42
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
9.2
9.1
18
20
S02.10
ICD-10 Finland
Fracture of base of skull, closed
15.9
9.1
14
9
G40.89
ICD-10 Finland
Other epilepsy
15.9
9.1
14
9
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
4.3
9.0
23
55
A86
ICD-10 Finland
Unspecified viral encephalitis
18.9
9.0
13
7
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
8.1
8.9
19
24
Z02.4
ICD-10 Finland
Examination for driving licence
0.4
8.9
53
1127
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.9
8.8
42
152
W22
ICD-10 Finland
Striking against or struck by other object(s)
2.7
8.8
50
199
X58
ICD-10 Finland
Exposure to other specified factors
2.1
8.8
91
472
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.6
8.7
29
84
Z02.7
ICD-10 Finland
Issue of medical certificate
2.7
8.7
48
188
A04
ICPC
Weakness/tiredness general
2.2
8.7
82
410
N05AA01
ATC
chlorpromazine; systemic, rectal
7.8
8.7
19
25
G30.0
ICD-10 Finland
Alzheimer disease with early onset
50.7
8.7
10
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
8.7
198
1329
F32.1
ICD-10 Finland
Moderate depressive episode
3.0
8.6
39
137
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.9
8.6
19
40
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.9
8.6
40
143
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
9.2
8.6
17
19
G30.8
ICD-10 Finland
Other Alzheimer disease
27.9
8.5
11
*
K92.0
ICD-10 Finland
Haematemesis
4.0
8.5
24
62
S06.8
ICD-10 Finland
Other intracranial injuries
91.3
8.4
9
*
N06AA12
ATC
doxepin; systemic
2.8
8.4
42
156
L89
ICD-10 Finland
Decubitus ulcer and pressure area
6.9
8.4
20
30
IGY99
NOMESCO Finland
Other psychiatric treatment contact
5.0
8.4
18
37
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
4.8
8.4
19
41
A01
ICPC
Pain general/multiple sites
2.5
8.4
55
235
N30.0
ICD-10 Finland
Acute cystitis
2.2
8.4
77
381
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
3.1
8.4
36
123
80090
ICD-8 Finland
Fracture of vault of skull, Late effect
+∞
8.3
8
*
29320
ICD-8 Finland
Psychosis associated with other cerebral condition, Epilepsy
+∞
8.3
8
*
AAD15
NOMESCO Finland
Evacuation of traumatic intracerebral haematoma
+∞
8.3
8
*
A46
ICD-10 Finland
Erysipelas
2.0
8.3
92
489
A41.9
ICD-10 Finland
Sepsis, unspecified
3.5
8.3
28
82
N06AA06
ATC
trimipramine; systemic
4.0
8.2
23
59
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
3.6
8.2
27
78
SPAT1254
SPAT
Administration of medicine
2.1
8.2
80
406
H53.4
ICD-10 Finland
Visual field defects
4.6
8.2
19
42
F32
ICD-10 Finland
Depressive episode
3.1
8.1
33
109
N06AB05
ATC
paroxetine; oral
2.9
8.1
39
142
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.6
8.1
48
195
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
17.5
8.1
12
7
C03CA01
ATC
furosemide; systemic
1.7
8.1
184
1231
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
22.4
8.0
11
5
Z72.8
ICD-10 Finland
Other problems related to lifestyle
22.4
8.0
11
5
R55
ICD-10 Finland
Syncope and collapse
2.2
8.0
70
339
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
7.4
8.0
18
25
TKC20
NOMESCO Finland
Catheterisation of bladder
2.4
7.9
54
235
F61.0
ICD-10 Finland
Mixed personality disorders
6.2
7.9
20
33
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
8.6
7.8
16
19
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
8.6
7.8
16
19
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
8.6
7.8
16
19
N02AA05
ATC
oxycodone; systemic
1.9
7.8
102
574
SPAT1167
SPAT
Insertion of urinary catheter
3.7
7.8
24
66
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.0
7.8
22
57
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
45.6
7.7
9
*
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
7.6
7.7
17
23
S42.0
ICD-10 Finland
Fracture of clavicle
3.6
7.6
25
72
3459X
ICD-9 Finland
Epilepsy, unspecified
25.4
7.6
10
*
T91.8
ICD-10 Finland
Sequelae of other specified injuries of neck and trunk
25.4
7.6
10
*
R4150
NOMESCO Finland
Neuropsychological rehabilitation
10.2
7.6
14
14
N03AX12
ATC
[U] gabapentin; oral
2.0
7.5
95
529
31099
ICD-8 Finland
Borderline mental retardation, Other and unspecified
81.0
7.4
8
*
N03AG04
ATC
vigabatrin; oral
81.0
7.4
8
*
ZY000
NOMESCO Finland
Hospital inpatient
7.8
7.4
16
21
N05AC01
ATC
periciazine; systemic
13.6
7.4
12
9
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
7.4
143
910
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
7.4
69
344
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.2
7.3
64
310
S00.0
ICD-10 Finland
Superficial injury of scalp
4.2
7.3
19
46
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
9.5
7.3
14
15
V89
ICD-10 Finland
Motor- or nonmotor-vehicle accident, type of vehicle unspecified
+∞
7.3
7
*
29398
ICD-8 Finland
Psychosis associated with other cerebral condition, Alia definita
+∞
7.3
7
*
F06.6
ICD-10 Finland
Organic emotionally labile [asthenic] disorder
+∞
7.3
7
*
SPAT1240
SPAT
Therapeutic discussion
2.3
7.3
57
264
SPAT1360
SPAT
Extensive global examination
2.7
7.3
39
151
G40.10
ICD-10 Finland
Simple partial seizures
16.0
7.2
11
7
34510
ICD-8 Finland
Epilepsy, """"Grand mal""""
30.4
7.2
9
*
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
30.4
7.2
9
*
R63.1
ICD-10 Finland
Polydipsia
30.4
7.2
9
*
R47.0
ICD-10 Finland
Dysphasia and aphasia
8.1
7.1
15
19
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
7.1
80
427
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
8.9
7.1
14
16
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
10.2
7.1
13
13
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
3.6
7.0
23
66
N05CD08
ATC
midazolam; nasal, systemic
3.9
7.0
20
52
S00.1
ICD-10 Finland
Contusion of eyelid and periocular area
4.5
7.0
17
39
N80
ICPC
Head injury other
5.6
7.0
19
35
30180
ICD-8 Finland
Personality disorders, Immatura
14.0
6.9
11
8
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.9
6.9
31
109
OAB48, ,
SPAT
0.2
6.8
9
368
R52.2
ICD-10 Finland
Other chronic pain
3.1
6.8
28
93
S01.3
ICD-10 Finland
Open wound of ear
6.8
6.8
16
24
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
6.8
6.8
16
24
E86
ICD-10 Finland
Volume depletion
4.2
6.8
18
44
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
6.8
101
591
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
9.5
6.8
13
14
S82.1
ICD-10 Finland
Fracture of upper end of tibia
6.2
6.8
17
28
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
5.8
6.8
18
32
M03BX01
ATC
baclofen; systemic
5.8
6.8
18
32
SPAT1234
SPAT
Support of social functional capacity
3.0
6.8
29
99
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
40.5
6.8
8
*
P15
ICPC
Chronic alcohol abuse
3.3
6.8
25
78
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
3.3
6.8
25
78
F60.8
ICD-10 Finland
Other specific personality disorders
16.9
6.8
10
6
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
6.7
99
578
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
7.3
6.7
15
21
N03AX15
ATC
zonisamide; oral
22.8
6.7
9
*
29599
ICD-8 Finland
Schizophrenia, Unspecified type
22.8
6.7
9
*
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
22.8
6.7
9
*
N29
ICPC
Neurological sympt/complt other
6.5
6.7
16
25
F34.1
ICD-10 Finland
Dysthymia
3.0
6.7
29
100
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
7.9
6.6
14
18
Z3231
NOMESCO Finland
Registered nurse
1.7
6.6
154
1027
H03AA01
ATC
levothyroxine sodium; systemic
1.8
6.6
107
644
SPAT1301
SPAT
No procedures
1.7
6.6
158
1062
F20.5
ICD-10 Finland
Residual schizophrenia
12.4
6.6
11
9
Y94.0
ICD-10 Finland
Accident at home
4.2
6.6
17
41
N05BB01
ATC
hydroxyzine; systemic
2.6
6.6
39
159
Y04.9
ICD-10 Finland
Assault by bodily force by unknown person
7.5
6.4
14
19
ADB00
NOMESCO Finland
Implantation of vagus nerve stimulating device
70.5
6.4
7
*
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
70.5
6.4
7
*
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
14.5
6.4
10
7
S82.6
ICD-10 Finland
Fracture of lateral malleolus
2.6
6.4
37
149
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
4.1
6.4
17
42
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
6.4
186
1313
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
6.7
6.4
15
23
SPAT1216
SPAT
Assessment of functional ability
1.9
6.4
78
429
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
6.3
82
459
S52.0
ICD-10 Finland
Fracture of upper end of ulna
6.1
6.3
16
27
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.7
6.3
33
126
Y09
ICD-10 Finland
Assault by unspecified means
11.2
6.3
11
10
RS230, ,
NOMESCO Finland
11.2
6.3
11
10
D12
ICPC
Constipation
3.1
6.3
26
87
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
+∞
6.3
6
*
29330
ICD-8 Finland
Psychosis associated with other cerebral condition, Intercranial neoplasm
+∞
6.3
6
*
F06.33
ICD-10 Finland
Organic mood syndrome
+∞
6.3
6
*
OAB95, ,
SPAT
0.1
6.2
*
208
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
27.0
6.2
8
*
RS140, ,
NOMESCO Finland
27.0
6.2
8
*
R45.1
ICD-10 Finland
Restlessness and agitation
27.0
6.2
8
*
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
27.0
6.2
8
*
3454A
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]
27.0
6.2
8
*
Y04.2
ICD-10 Finland
Assault by bodily force by friend
27.0
6.2
8
*
3451A
ICD-9 Finland
Epilepsy, Generalised convulsive epilepsy
27.0
6.2
8
*
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
27.0
6.2
8
*
K90
ICPC
Stroke/cerebrovascular accident
3.6
6.2
20
57
SPAT1251
SPAT
Organisation of medication
3.1
6.1
25
83
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
12.7
6.1
10
8
F60.2
ICD-10 Finland
Dissocial personality disorder
12.7
6.1
10
8
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
12.7
6.1
10
8
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
6.1
99
596
F41.8
ICD-10 Finland
Other specified anxiety disorders
3.7
6.1
19
53
S72.3
ICD-10 Finland
Fracture of shaft of femur
10.2
6.0
11
11
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
10.2
6.0
11
11
B18.2
ICD-10 Finland
Chronic viral hepatitis C
5.3
6.0
17
33
S62.6
ICD-10 Finland
Fracture of other finger
2.8
6.0
29
106
V19
ICD-10 Finland
Pedal cyclist injured in other and unspecified transport accidents
3.9
6.0
17
44
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
77
62
14.20
80.12
4.7
5.0
359.45
356.75
umol/l
0.04
62
53
153
716
2.55
19.99
1.8
1.7
1033.43
1132.05
nmol/l
0.77
112
545
304
2033
2.06
15.84
7.2
7.1
1.21
1.21
mmol/l
0.11
257
1736
281
1868
2.00
14.45
7.0
6.4
1.21
1.21
mmol/l
0.22
254
1702
137
722
2.18
13.03
2.1
1.9
—
—
—
0
0
97
501
2.13
9.50
2.0
1.8
—
—
—
0
0
62
265
2.50
9.44
1.8
1.6
—
—
—
0
0
121
687
1.97
9.13
3.2
3.7
0.82
0.82
mmol/l
0.00
108
650
96
502
2.10
9.09
2.1
1.8
—
—
—
0
0
194
1293
1.76
8.73
3.3
2.1
299.26
361.73
u/l
0.25
180
1218
203
1376
1.74
8.58
3.1
2.7
50.42
62.21
u/l
2.45
189
1281
234
1669
1.68
8.09
2.1
1.9
94.17
94.65
pmol/l
0.05
135
876
245
1798
1.64
7.41
5.9
5.1
34.17
35.55
g/l
2.61
222
1685
75
390
2.06
7.16
1.8
2.1
358.52
369.08
nmol/l
0.18
67
363
381
4377
0.60
7.04
4.9
5.0
2.72
2.72
mmol/l
0.01
332
4052
301
2345
1.60
6.98
6.3
6.7
9.76
11.93
umol/l
5.25
278
2227
371
4274
0.62
6.66
4.4
4.4
1.35
1.40
mmol/l
1.59
321
3949
155
1037
1.68
6.59
2.2
2.1
2.84
3.07
mg/l
0.63
127
891
190
1349
1.61
6.35
3.4
3.5
2.33
2.35
mmol/l
1.01
155
1192
358
4137
0.63
6.18
3.9
4.0
1.45
1.33
mmol/l
1.88
310
3803
14
21
6.80
6.06
1.3
2.2
154.33
66.09
umol/l
—
6
11
268
2085
1.54
5.90
6.8
6.3
26.76
27.41
%
0.44
244
1959
378
4300
0.63
5.83
4.3
4.5
4.53
4.58
mmol/l
0.46
329
4000
23
75
3.15
5.82
1.8
1.3
26.07
16.67
e6/l
0.23
15
58
72
399
1.92
5.74
3.6
3.8
2.53
1.85
mmol/l
0.75
60
333
141
952
1.64
5.69
1.7
1.5
16.99
20.72
nmol/l
2.55
120
806
202
1488
1.55
5.64
4.2
3.5
31.32
34.14
u/l
0.62
187
1421
316
2566
1.52
5.59
7.6
4.9
6.56
6.74
mmol/l
0.88
297
2411
262
2048
1.52
5.53
6.5
6.1
58.13
57.24
%
0.55
238
1931
11
405
0.26
5.48
1.2
1.7
—
—
—
0
0
223
1687
1.53
5.48
5.0
3.6
31.37
35.99
ng/l
0.40
168
1197
267
2099
1.51
5.47
15.9
14.7
1.13
1.30
inr
3.59
73
615
307
2488
1.51
5.41
11.7
9.6
4.63
4.10
e9/l
2.29
260
2172
69
1150
0.54
5.38
2.3
2.9
0.63
0.79
ug/l
1.47
44
740
85
509
1.79
5.30
8.2
8.5
2.45
1.07
mmol/l
2.18
69
415
390
3333
1.54
5.27
8.3
8.0
78.77
79.47
u/l
0.13
363
3128
92
569
1.73
5.13
2.3
1.8
1.83
1.49
%
1.91
75
502
332
2752
1.49
5.12
6.3
4.2
705.50
1824.08
e6/l
—
10
48
93
578
1.73
5.10
5.2
6.1
1.05
1.03
mmol/l
0.29
86
545
49
247
2.07
5.10
1.9
1.3
—
—
—
0
0
99
635
1.67
4.83
2.4
2.3
2.49
2.31
g/l
1.81
90
594
125
852
1.60
4.79
1.7
1.7
462.80
7862483.16
pmol/l
0.50
103
725
24
93
2.65
4.52
2.8
2.3
137.22
128.85
g/l
0.81
18
67
207
1605
1.45
4.26
2.6
2.3
72.22
76.84
nmol/l
1.26
184
1433
72
438
1.74
4.25
4.4
3.3
—
—
—
0
0
113
1580
0.64
4.23
4.2
4.1
22.24
21.23
%
0.33
46
731
81
510
1.68
4.23
8.4
8.4
5.38
5.11
kpa
1.60
76
488
81
511
1.68
4.20
8.4
8.4
12.16
12.08
kpa
0.04
76
492
92
605
1.62
4.06
2.3
2.4
19.98
23.50
%
1.62
78
535
9
14
6.50
3.99
3.0
1.9
—
—
—
0
0
54
308
1.83
3.96
2.9
1.5
—
—
—
0
0
69
427
1.70
3.84
2.2
2.5
0.21
0.21
g/l
0.08
63
395
28
129
2.23
3.69
1.4
1.2
—
—
—
0
0
120
858
1.50
3.65
3.4
3.9
1373.88
278.03
ng/l
0.38
96
680
35
181
1.99
3.45
2.0
2.0
—
—
—
0
0
27
127
2.18
3.40
2.2
1.5
234.21
286.95
ug/g
0.55
14
77
123
898
1.47
3.36
4.5
3.8
1.02
1.02
kg/l
0.24
15
125
131
969
1.46
3.35
1.8
1.8
1.25
1.26
mg/l
0.01
103
757
197
1570
1.39
3.31
3.7
3.2
—
—
—
0
0
8
15
5.39
3.19
1.0
1.3
—
—
—
0
0
50
301
1.72
3.10
4.9
3.7
2.13
1.60
mmol/l
0.52
40
231
191
1530
1.37
3.07
4.8
3.8
115.99
160.05
e6/l
0.31
141
1099
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
8
16
5.05
3.05
1.1
1.3
—
—
—
0
0
97
693
1.48
2.95
2.4
2.4
12.41
13.13
umol/l
0.45
91
653
169
1338
1.37
2.90
3.8
3.3
281.81
113.37
e6/l
0.31
132
1037
121
907
1.42
2.86
2.8
2.6
7.03
5.11
e6/l
0.51
107
822
345
3063
1.32
2.62
4.7
3.6
14.54
14.76
pmol/l
0.83
304
2770
98
718
1.44
2.62
3.2
3.3
2.44
2.45
mmol/l
0.46
79
639
50
316
1.64
2.62
3.6
4.0
1.22
1.22
mmol/l
0.05
41
286
162
1981
0.74
2.59
4.3
4.8
3.26
2.35
ug/l
0.45
122
1774
51
326
1.62
2.56
5.1
3.6
5.24
5.13
kpa
0.31
46
314
5
7
7.19
2.55
1.0
1.0
3.68
4.90
umol/l
—
5
7
7
16
4.41
2.48
1.9
2.8
—
—
—
0
0
7
16
4.41
2.48
1.9
2.8
—
—
—
0
0
29
163
1.82
2.31
2.1
1.7
—
—
—
0
0
14
59
2.40
2.30
1.1
1.1
—
—
—
0
0
22
113
1.98
2.27
1.5
1.6
—
—
—
0
0
8
23
3.51
2.27
2.1
2.5
—
—
—
0
0
5
9
5.59
2.21
1.8
1.9
21.94
16.98
umol/l
—
5
9
32
188
1.74
2.21
1.9
2.0
3.09
1.85
ug/l
0.27
26
171
95
714
1.40
2.21
3.5
3.0
3.43
1.53
e6/l
0.72
47
408
242
2089
1.27
2.12
4.3
3.5
0.00
0.00
estimate
-0.00
41
367
5
10
5.03
2.07
1.0
1.8
0.71
1.15
ug/l
—
5
10
239
2066
1.27
2.06
5.6
4.8
0.00
0.00
estimate
-0.00
44
391
7
20
3.53
2.06
1.9
2.6
—
—
—
0
0
239
2071
1.26
2.00
4.3
3.5
0.00
0.00
estimate
0.50
45
416
0
52
0.00
1.89
0.0
1.5
—
—
—
0
0
148
1218
1.29
1.87
3.9
3.2
0.62
0.47
e6/l
0.25
112
923
134
1089
1.30
1.86
4.9
3.7
0.00
0.01
estimate
0.69
41
375
60
430
1.44
1.83
3.0
2.6
28.42
34.52
u/l
0.82
53
369
17
89
1.94
1.71
2.7
2.6
17.62
16.43
%
—
10
48
0
49
0.00
1.69
0.0
1.7
—
—
—
0
0
31
196
1.61
1.68
2.5
1.8
1.55
1.46
g/l
0.21
26
176
7
25
2.82
1.65
2.3
3.0
34157.14
35584.20
ug/l
—
7
25
17
91
1.89
1.61
2.1
1.3
—
—
—
0
0
17
91
1.89
1.61
2.1
1.3
—
—
—
0
0
53
382
1.43
1.59
2.5
2.4
5.23
8.69
ug/l
1.03
44
340
23
137
1.71
1.57
1.7
1.3
5.87
8.16
u/l
0.60
15
106
202
1760
1.23
1.53
3.0
2.6
140.34
149.24
ug/l
0.19
175
1624
11
51
2.18
1.51
1.2
1.6
—
—
—
0
0
11
51
2.18
1.51
1.2
1.6
—
—
—
0
0
6
21
2.87
1.50
2.7
2.4
—
—
—
0
0
17
94
1.83
1.48
4.4
4.4
5.32
5.09
kpa
0.75
17
94
464
4828
0.78
1.46
36.1
21.2
132.81
137.42
g/l
7.45
454
4750
15
80
1.90
1.45
1.1
1.8
—
—
—
0
0
15
80
1.90
1.45
1.1
1.8
—
—
—
0
0
7
28
2.52
1.45
1.3
1.1
—
—
—
0
0
7
28
2.52
1.45
1.3
1.1
—
—
—
0
0
464
4825
0.78
1.42
35.9
21.0
4.40
4.54
e12/l
6.17
450
4689
65
496
1.35
1.41
11.6
6.5
—
—
—
0
0
9
40
2.27
1.40
1.0
1.1
—
—
—
0
0
464
4822
0.79
1.38
35.7
21.1
252.59
244.02
e9/l
1.74
450
4696
6
23
2.62
1.37
1.0
1.0
—
—
—
0
0
20
120
1.69
1.35
1.1
1.2
—
—
—
0
0
44
317
1.42
1.35
2.6
4.1
75.03
83.99
ng/l
0.69
36
293
464
4819
0.79
1.34
36.1
21.3
39.43
40.66
%
4.12
428
4502
20
121
1.67
1.32
1.1
1.2
—
—
—
0
0
400
4216
0.82
1.31
4.7
4.5
6.00
6.01
mmol/l
0.00
344
3859
5
18
2.79
1.28
1.4
1.1
—
—
—
0
0
8
35
2.30
1.27
2.0
1.5
—
—
—
0
0
68
533
1.31
1.25
3.1
2.9
5.42
9.70
umol/l
2.48
48
481
124
1053
1.23
1.19
3.3
2.4
—
—
—
0
0
6
26
2.32
1.18
2.5
1.3
—
—
—
0
0
380
4010
0.84
1.18
6.7
5.9
41.11
40.20
mmol/mol
0.74
338
3738
8
39
2.06
1.15
1.0
1.2
—
—
—
0
0
7
31
2.27
1.10
1.0
1.1
—
—
—
0
0
14
81
1.74
1.09
1.4
1.2
41.02
41.16
u/l
0.00
14
71
33
238
1.41
1.04
1.2
1.2
54.64
121.21
iu/ml
—
8
94
7
34
2.07
1.03
1.3
1.1
—
—
—
0
0
7
34
2.07
1.03
1.3
1.1
—
—
—
0
0
24
163
1.49
1.03
2.8
2.8
—
—
—
0
0
47
362
1.32
1.00
1.6
3.2
221.87
226.89
ng/l
0.02
38
327
9
48
1.89
1.00
1.1
2.3
—
—
—
0
0
16
99
1.63
1.00
6.6
4.3
18.70
26.97
mg/l
—
10
68
9
49
1.85
0.99
1.2
1.9
—
—
—
0
0
9
49
1.85
0.99
1.2
1.9
—
—
—
0
0
9
49
1.85
0.99
1.2
1.9
—
—
—
0
0
90
755
1.23
0.98
3.5
2.8
1.63
1.05
e6/l
0.54
41
446
0
29
0.00
0.98
0.0
1.3
—
—
—
0
0
17
108
1.59
0.97
1.5
1.3
—
—
—
0
0
391
4088
0.86
0.94
20.8
13.3
86.98
81.19
ml/min/173m2
5.05
312
3394
9
52
1.74
0.92
1.2
2.2
—
—
—
0
0
17
111
1.55
0.88
1.1
1.8
—
—
—
0
0
8
44
1.83
0.86
1.1
1.0
—
—
—
0
0
19
129
1.49
0.84
1.8
1.6
—
—
—
0
0
16
105
1.54
0.82
1.1
1.8
—
—
—
0
0
8
48
1.67
0.79
1.8
1.3
—
—
—
0
0
19
132
1.45
0.76
1.2
1.3
—
—
—
0
0
10
59
1.71
0.76
1.3
1.7
—
—
—
0
0
12
75
1.61
0.75
1.1
1.1
—
—
—
0
0
7
40
1.76
0.71
1.3
1.2
—
—
—
0
0
175
1598
1.14
0.70
4.5
3.6
—
—
—
0
0
7
41
1.71
0.70
1.0
1.3
—
—
—
0
0
7
41
1.71
0.70
1.3
1.2
—
—
—
0
0
104
1172
0.86
0.69
2.7
2.8
354.77
7179.78
umol/l
4.63
82
1022
124
1379
0.87
0.69
3.5
3.9
5.82
9.56
mg/mmol
0.95
79
896
12
77
1.57
0.68
1.8
3.6
2.58
0.99
%
0.40
12
71
24
179
1.35
0.67
1.8
1.8
—
—
—
0
0
7
43
1.63
0.67
1.1
1.4
0.33
0.40
nmol/l
—
7
32
50
413
1.23
0.66
2.0
1.9
—
—
—
0
0
5
28
1.79
0.66
1.2
1.1
184.20
585.22
u/l
—
5
23
12
78
1.55
0.65
6.8
3.8
57.83
59.33
%
0.17
12
78
12
78
1.55
0.65
1.2
1.9
—
—
—
0
0
459
4456
1.15
0.64
27.6
16.7
139.08
139.67
mmol/l
3.88
446
4342
443
4300
1.13
0.58
25.2
14.5
28.90
24.78
mg/l
1.61
379
3414
42
347
1.23
0.57
3.3
3.0
65.66
66.44
g/l
0.26
36
321
329
3143
1.11
0.57
4.0
4.2
14.48
11.94
mm/h
1.80
293
2889
6
36
1.67
0.56
1.8
3.0
—
—
—
0
0
6
38
1.58
0.54
4.3
2.2
—
—
—
0
0
311
2970
1.10
0.53
5.1
3.3
62.93
54.69
u/l
0.71
288
2780
31
250
1.25
0.53
2.6
2.7
0.21
0.23
e6/l
0.08
31
241
459
4473
1.13
0.53
27.5
16.8
3.98
3.99
mmol/l
0.44
446
4350
26
205
1.28
0.53
1.2
1.3
—
—
—
0
0
9
63
1.43
0.52
1.3
1.4
—
—
—
0
0
452
4619
0.89
0.51
12.7
10.7
27.38
28.32
u/l
0.47
430
4465
57
655
0.85
0.51
1.2
1.3
1.27
12.84
u/ml
3.91
15
260
9
65
1.39
0.50
1.3
1.4
—
—
—
0
0
9
65
1.39
0.50
1.3
1.4
—
—
—
0
0
9
65
1.39
0.50
1.3
1.4
—
—
—
0
0
40
474
0.83
0.50
3.1
4.4
3.37
39.66
ug/l
1.39
29
397
44
372
1.20
0.50
1.8
1.8
—
—
—
0
0
17
127
1.35
0.50
1.2
1.1
—
7.81
—
0
14
61
695
0.86
0.49
1.4
1.4
—
—
—
0
0
7
107
0.65
0.49
1.9
1.4
—
—
—
0
0
11
76
1.45
0.48
7.2
3.2
5.39
4.56
e9/l
0.35
11
76
12
85
1.42
0.47
1.8
1.5
—
—
—
0
0
7
48
1.46
0.47
1.0
1.8
—
—
—
0
0
110
1200
0.90
0.46
1.7
1.7
1.58
1.43
mmol/l
0.84
91
1014
13
94
1.39
0.46
3.2
2.2
153.43
4594.46
u/l
—
6
33
51
441
1.17
0.46
2.7
2.2
11.64
13.54
nmol/l
0.85
41
395
18
138
1.31
0.45
1.6
1.8
—
—
—
0
0
14
103
1.37
0.45
1.2
1.3
—
—
—
0
0
5
31
1.62
0.43
1.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
2.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
57.55
—
0
19
9
66
1.37
0.38
1.3
1.3
—
—
—
0
0
9
66
1.37
0.38
1.3
1.3
—
—
—
0
0
9
67
1.35
0.38
1.2
1.6
—
—
—
0
0
9
70
1.29
0.36
1.3
1.3
—
—
—
0
0
363
3724
0.93
0.36
29.8
17.3
15.26
15.05
%
0.26
358
3668
12
90
1.34
0.35
1.9
1.7
3.02
6.52
iu/l
—
6
26
6
44
1.37
0.34
2.0
1.3
—
—
—
0
0
6
47
1.28
0.32
1.2
1.1
0.81
3.18
u/ml
—
6
30
10
74
1.36
0.32
1.0
1.2
—
1.07
—
0
6
16
128
1.26
0.32
2.4
1.4
0.25
0.24
g/l
0.53
16
123
51
567
0.89
0.31
4.3
4.5
30.11
31.10
%
0.26
35
395
7
52
1.35
0.31
1.3
1.2
0.70
0.54
nmol/l
—
7
46
212
2030
1.07
0.31
3.5
2.6
—
—
—
0
0
8
64
1.25
0.27
1.1
1.7
—
—
—
0
0
141
1339
1.07
0.26
3.5
3.3
1814.19
1371.00
ng/l
0.33
114
1141
390
3821
1.06
0.25
5.8
4.3
1.98
2.24
mu/l
0.36
348
3479
271
2630
1.06
0.25
2.6
2.9
—
—
—
0
0
9
76
1.19
0.24
1.1
4.0
—
2567.70
—
0
10
63
680
0.92
0.24
1.4
1.3
17.87
32.22
iu/ml
1.14
16
225
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
2.74
—
0
5
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
5
43
1.16
0.21
1.2
1.3
105.58
163.92
pmol/l
—
5
43
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
9.15
—
0
14
9
112
0.80
0.20
1.6
1.3
—
—
—
0
0
15
128
1.18
0.18
2.9
2.0
—
—
—
0
0
8
68
1.18
0.16
1.0
1.1
—
21.27
—
0
11
29
263
1.11
0.16
1.1
1.3
—
60.15
—
0
19
9
80
1.13
0.15
1.1
1.2
—
—
—
0
0
9
81
1.11
0.15
1.3
1.6
—
—
—
0
0
12
103
1.17
0.13
1.1
1.8
1.47
0.89
nmol/l
—
7
88
13
114
1.14
0.11
1.2
1.4
—
—
—
0
0
92
889
1.04
0.10
1.4
1.2
0.74
1.69
u/ml
2.13
23
240
5
64
0.78
0.08
1.0
1.2
—
—
—
0
0
5
64
0.78
0.08
1.4
1.7
—
—
—
0
0
7
68
1.03
0.08
1.0
1.1
—
—
—
0
0
6
72
0.83
0.07
1.3
1.7
—
—
—
0
0
45
431
1.05
0.07
1.4
1.5
—
—
—
0
0
15
137
1.10
0.07
2.7
1.4
1.13
1.18
g/l
0.29
15
132
8
77
1.04
0.07
1.0
1.6
—
—
—
0
0
20
187
1.07
0.06
1.1
1.0
—
—
—
0
0
16
149
1.07
0.05
1.6
1.7
—
—
—
0
0
12
110
1.09
0.05
1.8
1.7
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
15
140
1.07
0.04
3.3
2.8
0.30
0.35
u/ml
—
6
74
37
359
1.03
0.03
2.6
2.7
66.85
64.14
ml/min/173m2
0.14
13
154
12
113
1.06
0.01
1.1
1.1
—
—
—
0
0
23
235
0.98
0.00
1.3
1.3
168.07
324.91
u/ml
0.58
23
208
140
1399
1.00
0.00
3.0
3.3
7.46
8.04
mmol/l
0.61
112
1174
13
135
0.96
0.00
2.0
2.4
107.47
83.57
ug/min
—
6
76
16
155
1.03
0.00
2.1
2.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
9
91
0.99
-0.00
1.2
1.4
—
—
—
0
0
9
97
0.93
-0.00
1.0
1.3
—
—
—
0
0
6
59
1.02
-0.00
6.7
4.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.1
—
77.82
—
0
9
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
19.72
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
50.67
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint F5_PERSBEHORG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_PERSBEHORG | 3.369 [2.8, 4.05] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.593 |
During the follow-up period (1.1.1998 — 31.12.2019), 534 out of 1449 females with F5_PERSBEHORG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_PERSBEHORG | 4.112 [3.58, 4.73] | < 0.001 |
| Birth year | 0.984 [0.98, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 1321 out of 3047 males with F5_PERSBEHORG died.
Mortality risk
Mortality risk for people of age
years, who have F5_PERSBEHORG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.306% | 0.696% |
| 5 | 2.45% | 4.059% |
| 10 | 5.875% | 10.45% |
| 15 | 10.264% | 18.921% |
| 20 | 17.597% | 30.434% |
Relationships between endpoints
↥Index endpoint: F5_PERSBEHORG – Personality and behavioural disorders due to brain disease, damage and dysfunction
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data