Benign neoplasm: Appendix

CD2_BENIGN_APPENDIX

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D12.1& Hospital discharge: ICD-8 — 21131 Cause of death: ICD-10 — D12.1& Cause of death: ICD-8 — 21131 2 out of 7 registries used, show all original rules.	362
4. Check minimum number of events None	362
5. Include endpoints None	362
6. Filter based on genotype QC (FinnGen only)	362

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D12
Name in latin: Neoplasma benignum appendicis vermiformis

NAME	CD2_BENIGN_APPENDIX
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D121
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	21131
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D121
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	21131
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Appendix based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Benign neoplasm: Appendix

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	2109	1194	910
Only index persons	1983	1129	854
Unadjusted period prevalence (%)
Whole population	0.03	0.03	0.03
Only index persons	0.04	0.04	0.03
Median age at first event (years)
Whole population	65.07	63.69	66.86
Only index persons	64.78	63.24	66.80

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	362	199	163
Unadjusted period prevalence (%)	0.07	0.07	0.07
Median age at first event (years)	64.90	62.46	67.88

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
320: Matched controls
3199

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D12.1

ICD-10 Finland

Benign neoplasm: Appendix

+∞

323.0

310

UJF32

NOMESCO Finland

Coloscopy

9.1

71.3

217

602

JEA01

NOMESCO Finland

Laparoscopic appendectomy

30.0

51.1

D12.0

ICD-10 Finland

Benign neoplasm: Caecum

21.4

36.4

D12.2

ICD-10 Finland

Benign neoplasm: Ascending colon

14.9

30.7

JFA15

NOMESCO Finland

Endoscopic polypectomy in colon

7.7

25.3

D37.3

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Appendix

141.0

25.0

D12.6

ICD-10 Finland

Benign neoplasm: Colon, unspecified

7.6

23.8

JFA98

NOMESCO Finland

Other transluminal endoscopic local operation on intestine

14.1

18.9

D12.8

ICD-10 Finland

Benign neoplasm: Rectum

7.0

17.1

UJF30

NOMESCO Finland

Ileoscopy through colon

4.4

16.9

178

D12.3

ICD-10 Finland

Benign neoplasm: Transverse colon

7.8

15.9

JFB31

NOMESCO Finland

Laparoscopic right hemicolectomy

16.1

15.1

K57.3

ICD-10 Finland

Diverticular disease of large intestine without perforation or abscess

3.1

14.5

392

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

2.4

12.0

134

731

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

2.4

11.3

126

683

WX408

NOMESCO Finland

General anesthesy, balanced

2.5

11.3

111

564

B01AB05

ATC

enoxaparin; parenteral

2.4

11.2

130

717

D12.5

ICD-10 Finland

Benign neoplasm: Sigmoid colon

4.7

10.1

K35.1

ICD-10 Finland

Acute appendicitis with peritoneal abscess

14.0

9.8

JFB30

NOMESCO Finland

Right hemicolectomy

8.5

9.5

21131

ICD-8 Finland

Benign neoplasm of other parts of digestive system, Appendicis

+∞

9.4

UJF45

NOMESCO Finland

Flexible sigmoidoscopy with biopsy

3.4

9.4

156

WX402

NOMESCO Finland

General anaesthesia

2.7

9.3

296

8240/3-C18.1

ICD-O-3

Neuroendocrine tumor, NOS, of appendix

51.4

8.7

8480/1-C18.1

ICD-O-3

Low grade appendiceal mucinous neoplasm of appendix

+∞

8.4

R10.3

ICD-10 Finland

Pain localized to other parts of lower abdomen

2.4

8.2

375

N02BE01

ATC

paracetamol; systemic, rectal

2.5

7.8

282

2392

C18.19

ICD-10 Finland

Malignant tumor in appendix other or unspecified histology

46.1

7.7

JN3BD

NOMESCO Finland

Extensive abdominal CT

2.7

7.6

225

C18.11

ICD-10 Finland

Malignant tumor of the appendix invasive carcinoma

81.9

7.4

JFB20

NOMESCO Finland

Ileocaecal resection

16.2

7.3

JAH01

NOMESCO Finland

Laparoscopy

4.4

7.2

WX302

NOMESCO Finland

Thoracal epidural anesthesy

3.3

6.8

107

K35.9

ICD-10 Finland

Acute appendicitis, unspecified

3.5

6.8

C18.10

ICD-10 Finland

Malignant tumor of the appendix without histology

23.1

6.7

GD1AA

NOMESCO Finland

Thorax X-ray examination

1.8

6.6

156

1087

D12.4

ICD-10 Finland

Benign neoplasm: Descending colon

7.1

6.6

JN3AE

NOMESCO Finland

Abdominal ultrasound examination

2.4

6.4

266

P01AB01

ATC

metronidazole; oral, rectal

1.9

6.4

133

885

K38.9

ICD-10 Finland

Disease of appendix, unspecified

+∞

6.3

Z04.8

ICD-10 Finland

Examination and observation for other specified reasons

2.5

6.2

218

D12.9

ICD-10 Finland

Benign neoplasm: Anus and anal canal

12.9

6.1

D37.4

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Colon

6.9

6.1

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(3022145) Colonoscopy Study observation

119

349

4.59

37.92

1.5

1.3

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

122

366

4.52

37.72

3.7

4.1

ug/l

3.9

41.0

1.07

100

312

(3024561) Albumin [Mass/volume] in Serum or Plasma

212

1330

2.43

15.16

5.8

4.5

g/l

34.7

35.4

1.05

202

1243

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

4.59

14.44

3.3

2.1

u/ml

0.3

0.4

0.65

(42870588) Differential panel, method unspecified - Blood

168

982

2.33

13.72

6.6

5.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

207

1383

2.16

11.51

4.7

4.1

—

(3044640) Blood type and Crossmatch panel - Blood

159

960

2.17

11.48

3.0

2.4

—

(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma

145

3.32

11.05

3.3

2.9

u/ml

80.3

2145.6

1.00

122

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

9.59

10.82

2.3

3.3

nmol/l

56.2

63.4

0.36

(3004789) Transferrin [Mass/volume] in Serum or Plasma

471

2.35

10.55

2.5

2.4

g/l

2.4

2.3

1.13

427

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

288

2.63

10.45

2.8

2.3

u/l

32.1

32.3

0.02

238

(40768804) Tissue Pathology biopsy report

185

1218

2.06

10.31

2.5

2.2

—

(3022948) Iron [Moles/volume] in Serum or Plasma

512

2.29

10.30

2.5

2.4

umol/l

12.2

12.8

0.43

465

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

229

1635

2.09

10.16

7.8

6.0

umol/l

12.3

11.2

0.77

222

1538

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

5.67

10.03

1.9

2.5

nmol/l

2.1

7.6

0.64

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

297

2373

2.40

9.54

10.3

7.3

u/l

79.4

78.3

0.21

285

2192

(3022096) Basophils/100 leukocytes in Blood

197

1353

2.00

9.48

7.0

5.6

0.6

0.7

0.41

187

1257

(3019069) Monocytes/100 leukocytes in Blood

202

1400

2.00

9.47

7.2

5.9

8.9

8.7

0.46

194

1310

(3002030) Lymphocytes/100 leukocytes in Blood

204

1419

2.00

9.46

7.1

5.7

26.2

27.3

0.69

193

1316

(3006504) Eosinophils/100 leukocytes in Blood

201

1393

2.00

9.40

7.1

5.6

2.9

2.8

0.01

193

1294

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

446

2.25

9.14

2.6

2.5

20.7

22.1

0.44

381

(3013707) Erythrocyte sedimentation rate by Westergren method

283

2238

2.21

8.97

4.8

4.2

mm/h

13.4

12.9

0.23

259

2028

(3002256) Pathology report gross observation

385

2.31

8.95

1.3

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

351

2.35

8.89

3.4

2.6

umol/l

6.1

8.4

1.10

304

(3018010) Neutrophils/100 leukocytes in Blood

200

1408

1.94

8.68

6.9

5.5

58.7

57.4

0.74

188

1314

(3013650) Neutrophils [#/volume] in Blood by Automated count

234

1743

1.97

8.51

11.9

8.9

e9/l

4.4

4.1

0.78

198

1537

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

122

733

2.00

8.38

2.7

2.2

—

(40768797) Stomach Pathology biopsy report

424

2.21

8.38

1.4

1.2

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

211

1534

1.90

8.08

8.0

6.7

mmol/l

1.2

1.76

186

1297

(3006315) Basophils [#/volume] in Blood

205

1496

1.85

7.56

7.2

5.4

e9/l

0.0

0.22

170

1285

(3001122) Ferritin [Mass/volume] in Serum or Plasma

178

1248

1.84

7.43

3.3

2.7

ug/l

135.8

128.7

0.16

171

1140

(3013115) Eosinophils [#/volume] in Blood

209

1540

1.85

7.42

7.4

5.7

e9/l

0.2

0.03

179

1350

(3021589) Normoblasts [#/volume] in Blood

185

1316

1.83

7.33

11.9

9.6

e9/l

0.0

0.29

146

1078

(3001604) Monocytes [#/volume] in Blood

203

1487

1.83

7.30

7.2

5.4

e9/l

0.6

0.41

169

1276

(4281824)

5.17

7.25

1.0

1.1

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

122

767

1.89

7.14

2.9

2.1

mg/l

2.8

3.1

1.32

110

652

(3023368) Bacteria identified in Blood by Culture

132

852

1.86

7.11

5.2

4.1

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

234

1801

1.85

7.05

6.2

4.6

mmol/l

6.6

6.7

0.58

222

1690

(3019198) Lymphocytes [#/volume] in Blood

205

1519

1.81

6.97

7.3

5.5

e9/l

1.7

1.9

1.73

172

1333

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

335

2946

2.84

6.80

23.2

14.9

mg/l

27.5

24.0

1.02

288

2359

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

194

1421

1.79

6.80

6.8

5.6

mmol/l

1.2

2.45

181

1275

(3032080) INR in Blood by Coagulation assay

179

1290

1.77

6.55

10.8

9.8

inr

1.3

0.24

366

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

101

613

1.90

6.50

4.0

3.9

ng/l

68.1

196.9

1.36

500

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

142

961

1.79

6.42

4.0

3.1

u/l

30.2

32.0

0.47

131

911

(3026008) Bacteria identified in Urine by Culture

140

968

1.73

5.73

3.3

3.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

175

1287

1.70

5.71

2.2

2.0

pmol/l

92.2

94.3

0.22

676

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

276

2.12

5.58

2.3

g/l

0.2

0.30

254

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

138

960

1.71

5.47

3.1

2.5

u/l

58.5

55.9

0.49

133

880

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

235

1884

1.71

5.43

4.0

3.2

u/l

51.9

51.4

0.03

228

1730

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

486

1.86

5.31

3.9

3.0

e6/l

1.1

2.1

1.51

265

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

141

2.47

5.16

4.1

3.6

mmol/l

23.9

24.4

0.46

128

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

3.20

5.15

1.5

1.4

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

3.20

5.15

1.5

1.4

—

(3042936) Bacteria identified in Isolate by Culture

444

1.87

5.11

2.4

1.8

—

(36304419) Bacteria [Presence] in Urine

120

820

1.69

5.00

3.8

3.2

—

(3002582) Erythrocytes [#/volume] in Urine

134

945

1.66

4.95

4.3

3.4

e6/l

15.2

113.0

0.83

104

735

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

613

1.75

4.86

3.8

3.0

mmol/l

2.5

0.00

542

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

165

1234

1.62

4.79

2.2

2.3

nmol/l

78.0

78.7

0.12

147

1086

(3002385) Erythrocyte distribution width [Ratio]

283

2426

1.76

4.73

29.3

18.5

14.1

13.8

1.99

278

2387

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

343

3146

2.72

4.65

14.7

10.7

u/l

25.1

25.2

0.05

337

3020

(3026782) Osmolality of Urine

622

1.71

4.59

3.7

3.1

mosm/kgh2o

528.0

548.9

0.39

530

(3020564) Creatinine [Moles/volume] in Serum or Plasma

342

3136

2.64

4.57

26.9

17.7

umol/l

82.6

79.0

0.86

342

3136

(3030467) Casts [#/volume] in Urine by Automated count

123

865

1.64

4.52

4.0

3.3

e6/l

1.3

0.5

0.49

651

(40758558) Short blood count panel - Blood

111

764

1.65

4.42

8.8

6.6

—

(3018095) Leukocytes [#/volume] in Urine

147

1085

1.60

4.41

5.3

3.9

e6/l

26.0

91.8

3.10

109

786

(3002032) Base excess in Venous blood by calculation

275

1.95

4.23

3.9

3.6

mmol/l

1.3

2.1

0.77

222

(3014111) Lactate [Moles/volume] in Serum or Plasma

262

1.96

4.15

8.9

6.3

mmol/l

1.2

1.3

0.37

246

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

2.85

4.08

1.2

1.4

—

(3027945) Reticulocytes/100 erythrocytes in Blood

386

1.80

4.08

2.2

2.6

1.7

1.8

0.21

349

(3021447) Carbon dioxide [Partial pressure] in Venous blood

279

1.92

4.06

3.9

3.6

kpa

6.0

5.8

0.63

268

(3007461) Platelets [#/volume] in Blood

348

3242

2.90

4.04

34.0

22.1

e9/l

247.8

245.6

0.22

340

3149

(3012544) pH of Venous blood

281

1.90

3.97

3.8

3.6

—

(3010813) Leukocytes [#/volume] in Blood

348

3245

2.87

3.97

34.0

22.1

e9/l

6.7

0.05

340

3143

(3026361) Erythrocytes [#/volume] in Blood

348

3245

2.87

3.97

34.0

22.1

e12/l

4.4

4.5

1.40

339

3144

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

101

2.47

3.90

2.2

ug/l

289.7

333.2

0.13

(3009542) Hematocrit [Volume Fraction] of Blood

297

2627

1.73

3.89

26.1

16.0

38.9

39.8

1.01

218

1804

(4035726)

284

1.88

3.85

1.4

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

315

1.84

3.83

3.8

3.6

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

313

2815

1.83

3.80

22.4

14.0

ml/min/173m2

76.3

77.5

0.42

273

2310

(3015377) Calcium [Moles/volume] in Serum or Plasma

142

1068

1.54

3.80

4.0

3.3

mmol/l

2.3

2.4

1.36

119

928

(3018418) pH of Serum or Plasma

130

961

1.55

3.75

4.5

3.9

7.4

0.10

172

(3037467) Urinalysis macro (dipstick) panel - Urine

241

2037

1.55

3.70

6.0

4.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

145

1102

1.53

3.67

4.1

3.3

—

(3044889) 12 lead EKG panel

253

2165

1.56

3.65

4.9

4.1

—

(3009214) Lutropin [Units/volume] in Serum or Plasma

3.03

3.62

1.1

1.2

u/l

11.0

8.1

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

118

2.30

3.60

1.5

2.1

g/l

0.0

0.7

2.00

102

(3007853) Bacteria identified in Skin by Aerobe culture

337

1.78

3.59

2.1

1.5

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

379

1.73

3.50

9.5

6.4

mmol/l

104.5

103.8

0.64

369

(3012095) Magnesium [Moles/volume] in Serum or Plasma

495

1.65

3.45

4.1

3.2

mmol/l

0.8

0.65

461

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

521

1.63

3.42

3.3

2.7

e6/l

0.7

1.1

1.27

297

(3045788) Cell count panel - Pleural fluid

3.78

3.37

1.1

—

(40761511) CBC panel - Blood by Automated count

330

3046

1.94

3.28

22.6

14.2

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

650

1.56

3.18

1.9

1.7

mg/l

1.3

0.02

506

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

600

1.57

3.14

3.5

3.0

ug/l

0.8

0.12

398

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

3.15

3.12

1.1

1.0

—

(3045424) Erythrocytes [Presence] in Urine

3.15

3.12

2.4

1.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

195

1628

1.43

2.84

2.7

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

127

982

1.45

2.80

3.2

3.1

ng/l

1141.2

1369.4

0.41

113

835

(3003396) Base excess in Arterial blood by calculation

346

1.66

2.78

8.9

7.3

mmol/l

0.8

1.3

0.48

283

(3000850) Epithelial cells [#/volume] in Urine

660

1.51

2.76

3.1

2.8

e6/l

3.8

4.5

0.46

583

(3037522) Nuclear Ab [Titer] in Serum

391

1.61

2.66

1.4

1.3

titre

547.7

475.6

0.14

101

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

2.36

2.62

1.9

1.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

151

1218

1.41

2.60

4.1

3.9

ng/l

31.0

66.6

0.70

106

896

(3027801) Oxygen [Partial pressure] in Arterial blood

344

1.63

2.60

9.1

7.2

kpa

13.2

12.0

0.76

334

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

344

1.63

2.60

9.1

7.2

kpa

5.3

5.1

0.63

332

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

300

2740

1.55

2.57

5.2

4.8

mu/l

2.0

0.07

284

2456

(3003694) ABO and Rh group [Type] in Blood

729

1.45

2.44

1.3

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

215

1.75

2.40

1.7

1.5

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

512

1.51

2.38

1.2

1.3

iu/ml

17.8

36.6

2.31

172

(3022217) INR in Platelet poor plasma by Coagulation assay

444

1.54

2.38

39.1

23.1

inr

1.4

1.3

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

142

1.90

2.30

1.4

2.1

g/l

1.5

1.6

0.18

127

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

172

1.81

2.29

1.6

1.3

—

(3004588) Protein electrophoresis panel - Serum or Plasma

228

1.69

2.22

1.8

2.4

—

(40768806) Pleura Pathology biopsy report

2.83

2.22

1.3

1.6

—

(3012441) Differential panel - Pleural fluid

2.83

2.22

1.2

1.3

—

(3045414) Leukocytes [Presence] in Urine

108

2.00

2.20

2.8

1.8

—

(3000991) Gas panel - Venous blood

245

1.66

2.18

12.4

7.5

—

(3021601) Nitrite [Presence] in Urine by Test strip

174

1469

1.36

2.16

5.8

5.2

estimate

0.0

0.00

268

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

305

2827

1.50

2.11

6.7

6.3

mmol/mol

39.7

40.4

0.63

292

2611

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

140

1.84

2.07

1.4

1.9

g/l

4.2

3.8

0.45

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

140

1.84

2.07

1.4

1.9

g/l

7.0

7.4

0.66

103

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

140

1.84

2.07

1.4

1.9

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

106

832

1.39

2.07

4.3

4.4

23.5

21.4

0.61

400

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

156

1.79

2.03

13.4

8.8

mmol/l

24.4

24.6

0.09

149

(3049717) Cytology report of Urine Cyto stain

128

1.85

1.95

1.9

3.1

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

687

1.39

1.90

3.7

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

271

1.58

1.89

2.2

2.7

ug/l

15.0

7.9

0.36

238

(3035350) Ketones [Presence] in Urine by Test strip

171

1462

1.32

1.87

4.2

3.9

estimate

0.0

0.00

273

(3007164) IgA [Mass/volume] in Serum or Plasma

556

1.42

1.85

1.5

1.4

g/l

2.6

0.05

320

(3000492) Spirometry study

257

1.58

1.83

1.5

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

3.37

1.75

1.2

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

156

1.72

1.74

12.2

9.3

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

196

1.64

1.72

2.8

2.2

nmol/l

9.7

12.8

1.56

177

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

3.88

1.72

1.4

g/l

1.0

—

(3019309) Folate [Moles/volume] in Red Blood Cells

644

1.37

1.72

1.8

1.7

nmol/l

1019.2

1186.8

0.84

490

(3009261) Glucose [Presence] in Urine by Test strip

172

1485

1.30

1.71

4.3

3.9

estimate

0.0

0.50

261

(3051611) Lipemic interference index of Serum or Plasma

2.62

1.67

3.9

3.1

—

(4062490)

2.62

1.67

1.3

1.2

—

(3044941) Cell count panel - Synovial fluid

2.36

1.61

1.6

1.5

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

2.36

1.61

1.4

1.1

—

(3026493) Urate [Moles/volume] in Serum or Plasma

100

807

1.33

1.60

3.2

2.7

umol/l

373.6

7191.2

3.46

690

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

404

1.43

1.56

1.5

1.4

—

(4306422)

2.46

1.54

1.5

1.2

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

3.36

1.53

1.6

1.8

u/ml

785.4

825.3

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

316

2994

1.44

1.50

5.5

5.3

mmol/l

2.6

2.7

0.96

296

2719

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

487

1.38

1.49

1.2

1.3

u/ml

21.4

12.2

0.34

189

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

2.47

1.49

3.6

4.1

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

288

1.48

1.47

1.7

1.5

0.48

249

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

1.91

1.47

4.4

2.7

mg/l

1.6

1.7

0.22

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

308

2908

1.40

1.47

4.6

4.7

mmol/l

1.4

1.5

0.84

293

2646

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

2.40

1.46

1.2

1.1

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.01

1.45

1.8

1.1

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

2.07

1.45

2.7

1.4

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

173

1.61

1.45

1.3

1.4

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

2.34

1.44

1.2

1.4

—

(3048689) Calprotectin [Mass/mass] in Stool

316

1.45

1.42

2.1

ug/g

165.0

156.2

0.03

249

(3025468) Yersinia sp identified in Specimen by Organism specific culture

2.28

1.41

1.2

1.4

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

2.28

1.41

1.2

1.4

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

2.28

1.41

1.2

1.4

—

(3035637) Corticotropin [Mass/volume] in Plasma

2.44

1.40

1.0

1.6

—

(3003434) Protein [Mass/volume] in Pleural fluid

2.22

1.38

1.2

1.3

g/l

34.3

33.2

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

2.22

1.38

1.2

1.4

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

2.22

1.38

1.2

1.4

—

(40768441) Liver Pathology biopsy report

2.63

1.37

2.0

1.2

—

(3028026) IgM [Mass/volume] in Serum or Plasma

192

1.55

1.37

1.6

g/l

0.8

1.4

1.93

172

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

308

2919

1.37

1.33

4.8

4.9

mmol/l

6.1

6.0

0.16

288

2640

(3004716) Salmonella sp identified in Stool by Organism specific culture

137

1.65

1.33

2.0

1.3

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

1.88

1.31

1.4

1.2

—

(4010399)

219

1.51

1.31

1.7

1.4

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

2.12

1.31

1.2

1.3

—

(3021960) Folate [Moles/volume] in Serum or Plasma

764

1.29

1.30

1.8

1.6

nmol/l

19.1

20.9

0.76

644

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

122

1038

1.26

1.29

6.3

5.2

ug/l

2.5

2.9

0.26

108

921

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

2.80

1.29

3.2

1.6

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

2.80

1.29

1.4

2.5

14.2

13.6

—

(3021788) Differential panel - Synovial fluid

2.03

1.28

1.7

1.6

—

(4094501)

1.85

1.27

1.2

1.1

—

(3000494) Fungus identified in Specimen by Culture

367

1.39

1.27

1.6

1.4

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

307

1.42

1.25

1.5

1.4

—

(3052851) Hemolysis interference index of Serum or Plasma

1.75

1.23

4.5

3.2

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

189

1.52

1.23

1.5

1.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

274

1.43

1.22

1.4

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

308

2929

1.35

1.21

4.7

mmol/l

4.5

4.6

0.79

291

2687

(3003327) Ova and parasites identified in Stool by Light microscopy

1.78

1.21

1.5

—

(3023520) Reticulocytes [#/volume] in Blood

284

1.42

1.19

2.3

2.7

e9/l

71.7

69.5

0.15

231

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

1.80

1.18

1.1

1.2

—

(3020682) Albumin/Creatinine [Ratio] in Urine

115

981

1.25

1.18

3.9

4.1

mg/mmol

11.8

9.9

0.14

609

(3009508) Creatinine [Moles/volume] in Urine

112

953

1.25

1.17

3.1

3.2

mmol/l

7.6

7.3

0.38

784

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

2.52

1.15

1.0

1.5

—

(3024928) Oxygen saturation in Venous blood

1.88

1.14

2.0

2.4

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

1.78

1.14

1.1

—

(3013512) EKG study

111

949

1.24

1.11

4.2

4.1

—

(3022313) Gas panel - Capillary blood

148

0.53

1.06

2.8

3.6

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

1.66

1.05

1.4

1.2

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

626

1.27

1.04

1.4

1.2

u/ml

1.9

1.4

0.25

158

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

296

2816

1.28

1.03

4.1

4.2

mmol/l

1.3

0.56

275

2544

(3014765) Yersinia sp identified in Stool by Organism specific culture

1.64

1.01

1.4

1.2

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

1.69

0.99

5.1

2.9

ug/min

101.9

81.4

—

(42529406) Shigella sp [Presence] in Stool by Culture

100

1.63

0.98

1.4

1.2

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.98

0.0

1.1

—

(3019060) Gas panel - Arterial blood

208

1.43

0.98

3.4

4.8

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

1.96

0.97

1.6

ug/l

15.3

16.9

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

175

1.46

0.96

1.2

iu/ml

172.8

132.6

—

(40768443) Skin Pathology biopsy report

150

1.50

0.95

1.3

1.2

—

(40768800) Prostate Pathology biopsy report

1.80

0.95

1.3

1.2

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.80

0.95

1.2

1.1

—

(3012516) Albumin [Mass/volume] in Urine

107

927

1.22

0.94

3.1

3.2

mg/l

53.6

191.1

0.78

593

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

360

1.32

0.93

1.9

—

(3025130) Human papilloma virus identified in Specimen

2.16

0.92

1.0

2.1

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

2.16

0.92

1.3

2.9

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

2.16

0.92

2.0

2.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

380

1.30

0.90

1.5

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

257

1.36

0.87

3.0

2.5

ml/min/173m2

67.8

62.1

0.42

(3008898) HLA-B27 [Presence]

1.59

0.85

1.0

1.1

—

(3047181) Lactate [Moles/volume] in Blood

1.61

0.85

4.8

7.5

mmol/l

1.2

0.12

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

402

1.28

0.84

1.4

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

181

1.41

0.82

1.2

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

805

1.21

0.82

1.5

1.6

mmol/l

1.3

0.02

666

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

190

1.40

0.81

1.8

1.7

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

1.58

0.79

1.3

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

1.61

0.79

1.2

1.7

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

1.61

0.79

1.5

—

(3037121) Protein [Mass/volume] in Urine

107

1.52

0.77

1.9

3.2

g/l

0.4

0.2

—

(36660697) Celiac disease serology panel - Serum

210

1.36

0.76

1.2

—

(3000570) Elastase.pancreatic [Mass/mass] in Stool

1.56

0.76

1.3

1.4

ug/g

209.0

278.9

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

204

1.35

0.71

1.6

1.7

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

1.94

0.71

1.0

1.2

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

1.94

0.71

2.2

2.3

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

1.72

0.70

5.3

2.8

—

885.4

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

170

1.38

0.69

3.0

2.5

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

1.68

0.68

1.0

1.6

32.0

32.6

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

360

1.25

0.67

2.0

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

1.80

0.66

1.0

1.2

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

112

1.45

0.64

1.7

2.8

—

(1616796) Gas panel - Central venous blood

1.58

0.59

2.8

3.4

—

(3020891) Body temperature

115

1.41

0.57

4.1

4.4

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

517

1.19

0.57

2.0

—

(3000330) Specific gravity of Urine by Test strip

150

1.35

0.57

4.1

4.4

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

1.63

0.56

7.3

3.0

u/ml

26.7

59.7

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

1.59

0.54

1.3

1.1

—

(3014051) Protein [Presence] in Urine by Test strip

1.49

0.54

3.2

2.2

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

1.50

0.54

2.5

1.8

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

1.55

0.53

1.8

1.6

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

1.55

0.53

1.2

—

(40761536) Microorganisms panel - Urine sediment

243

1.26

0.51

5.7

4.2

—

(3022621) pH of Urine by Test strip

190

1.28

0.49

3.1

2.7

—

(3023419) Bacteria identified in Sputum by Culture

1.57

0.49

2.1

3.2

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.60

0.46

1.6

1.7

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

103

1.37

0.46

1.9

2.1

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

392

0.83

0.44

7.4

7.0

—

(3043409) Potassium [Moles/volume] in Arterial blood

1.38

0.44

2.5

4.1

mmol/l

3.8

4.0

0.53

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

234

2247

1.12

0.44

4.4

4.0

pmol/l

14.8

0.22

222

2003

(3029937) Albumin [Presence] in Urine by Test strip

800

1.13

0.43

4.7

4.2

estimate

0.0

0.00

262

(3041067) Sjogrens syndrome-A extractable nuclear 52kD Ab [Units/volume] in Serum

1.62

0.43

1.0

1.2

—

94.4

—

(3019150) Specific gravity of Urine by Refractometry

647

1.14

0.42

4.1

4.2

kg/l

1.0

0.41

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

1.36

0.41

1.4

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

1.38

0.40

1.3

1.2

—

(3004451) EKG impression Narrative

0.00

0.40

0.0

1.4

—

(3035880) pH of Pleural fluid

0.00

0.40

0.0

1.1

—

(3022806) Fractional oxyhemoglobin in Capillary blood

1.43

0.39

2.0

1.9

86.1

90.1

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

1.39

0.38

1.0

1.2

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.35

0.38

1.1

1.2

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.33

0.38

2.6

1.7

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

135

1.27

0.36

1.1

1.0

—

(1761868) Lipid panel - Serum or Plasma

107

996

1.11

0.35

2.8

3.1

—

(3019832) Treponema pallidum Ab [Presence] in Serum

145

0.75

0.35

1.5

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

1.40

0.35

5.5

2.4

e9/l

3.4

4.8

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

1.40

0.35

3.5

2.6

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

1.37

0.34

5.3

2.9

58.2

59.3

—

(3021440) Promyelocytes/100 leukocytes in Blood

238

1.19

0.33

4.2

4.5

0.0

0.2

—

(40768793) Breast Pathology biopsy report

0.68

0.33

1.3

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.68

0.33

1.5

1.7

—

(3044290) Cell count panel - Cerebral spinal fluid

1.31

0.33

1.7

1.4

—

(40760892) CBC W Ordered Manual Differential panel - Blood

650

1.11

0.32

3.6

4.7

—

(3020044) Glucose [Moles/volume] in Cerebral spinal fluid

1.25

0.29

1.7

1.2

mmol/l

3.0

4.0

—

(1002224) Polysomnography panel

109

0.73

0.29

1.0

1.1

—

(3039443) Prostate specific Ag panel - Serum or Plasma

1.23

0.29

1.1

1.5

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

665

1.10

0.28

1.4

1.8

pmol/l

438.8

445.2

0.07

545

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

1.26

0.26

1.0

1.2

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

105

1.25

0.25

1.1

1.0

—

(3037756) Immunofixation for Serum or Plasma

1.19

0.25

1.1

1.9

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.17

0.24

2.2

1.3

—

(3004616) Nuclear Ab [Presence] in Serum

1.32

0.23

1.2

—

(3044927) Protein electrophoresis panel - Urine

1.32

0.23

1.2

1.1

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

1.29

0.23

1.2

nmol/l

—

(1761482) Bacteria [#/volume] in Urine by Culture

1.26

0.23

4.3

5.4

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

1.22

0.22

1.2

—

(3017181) Myelocytes/100 leukocytes in Blood

258

1.13

0.22

4.2

4.3

0.7

0.8

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

135

1.19

0.22

1.3

1.4

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3020229) Cytomegalovirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3016244) Insulin [Units/volume] in Serum or Plasma

0.00

0.21

0.0

2.5

—

16.6

—

(3037556) Urate [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

(40765096) Chromosome analysis panel by Banding

0.00

0.21

0.0

1.0

—

(3008536) Aspergillus sp Ab [Presence] in Serum

0.00

0.21

0.0

1.3

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

7.7

—

0.7

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

386

0.90

0.21

4.1

4.9

32.8

32.5

0.04

244

(3003171) Aldosterone [Moles/volume] in Serum or Plasma --upright

0.00

0.21

0.0

1.2

—

417.7

—

(3028433) Virus identified in Specimen by Culture

0.00

0.21

0.0

1.2

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

1.25

0.20

1.2

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

1.20

0.20

1.8

1.3

—

(21494755) Public health laboratory ask at order entry panel

207

0.86

0.19

1.5

1.4

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

1.18

0.19

1.8

1.3

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

1.18

0.19

1.0

1.8

—

(3019230) Fractional oxyhemoglobin in Venous blood

1.16

0.19

1.2

1.8

66.4

57.9

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

196

0.86

0.19

3.0

3.7

mmol/l

1.8

1.9

—

151

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

1.15

0.17

1.0

1.6

—

(3003181) Sodium [Moles/volume] in Urine

1.13

0.17

1.6

1.3

mmol/l

43.4

62.4

—

(3021901) Oxygen saturation in Capillary blood

1.13

0.17

4.0

2.7

—

(3025941) Bacteria identified in Stool by Culture

159

1.14

0.15

1.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

190

1.11

0.13

2.2

1.7

—

(3015171) Extractable nuclear Ab [Units/volume] in Serum

105

1.15

0.11

1.4

1.2

—

2.1

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.15

0.10

1.7

1.6

—

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

1.14

0.10

1.2

nmol/l

0.6

0.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

174

1.10

0.09

2.2

1.6

—

(3019225) pH of Specimen

301

1.07

0.09

3.4

4.4

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.05

0.08

2.7

1.6

—

(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid

1.05

0.08

1.8

1.4

e6/l

39.5

163.6

—

(3016543) Leukocytes [#/volume] in Cerebral spinal fluid

1.05

0.08

1.8

1.3

e6/l

18.7

7.8

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

1.04

0.08

1.0

1.5

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

277

0.93

0.08

3.2

1.9

nmol/l

352.7

382.8

0.45

251

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.83

0.08

2.4

3.3

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

117

1.12

0.08

1.4

1.7

—

(40761535) Cells panel - Urine sediment

266

0.94

0.08

3.8

3.3

—

(40760888) Immunoglobulin light chains.free panel - Serum

1.07

0.07

2.5

4.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

305

0.95

0.06

1.5

1.6

—

(3001019) Free T4 and TSH panel - Serum or Plasma

109

1.10

0.06

1.2

1.8

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

117

1157

1.02

0.03

4.6

4.1

—

(4034850)

1.07

0.01

4.4

10.6

—

(3041096) Erythrocytes [Presence] in Urine by Automated

816

0.99

0.00

4.5

3.6

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

128

1.02

0.00

1.5

1.9

—

(4015189)

0.00

0.0

3.0

—

(3003129) Base excess in Capillary blood by calculation

0.00

0.0

1.1

—

3.9

—

(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.3

—

(4198724)

0.00

0.0

1.8

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

0.94

0.00

1.8

1.2

mg/l

423.8

497.5

—

(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative

0.00

0.0

1.0

—

(3012741) Chlamydophila pneumoniae IgA Ab [Titer] in Serum

0.00

0.0

1.0

—

(3007916) DNA double strand Ab [Titer] in Serum

0.00

0.0

1.2

—

(3017962) TCRG gene rearrangements [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.2

—

(21494814) CD8 cells/100 lymphocytes in Specimen

0.00

0.0

1.6

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

0.0

1.3

—

(3005685) Amylase.salivary [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.0

—

52.4

—

(3014891) Appearance of Pleural fluid

0.00

0.0

1.2

—

(3019083) Insulin-like growth factor [Moles/volume] in Serum or Plasma

0.00

0.0

1.8

—

(3020073) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Specimen

0.00

0.0

1.7

—

(3006695) Toxoplasma gondii DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(723474) SARS-CoV-2 (COVID-19) IgG Ab [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.3

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.0

—

(3009876) Amylase isoenzyme 3 panel - Serum or Plasma

0.00

0.0

1.2

—

(3027300) Silver Birch IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3002067) Lambda light chains [Mass/time] in 24 hour Urine

0.00

0.0

2.4

—

(40757373) Influenza virus identified in Isolate

0.00

0.0

1.7

—

(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma

1.02

0.00

1.2

u/l

76.8

16.7

—

(3038769) Chlamydophila pneumoniae IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

14.4

—

(4133840)

0.00

0.0

1.0

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

0.0

1.3

—

(3022907) Direct antiglobulin test.polyspecific reagent [Presence] on Red Blood Cells

0.00

0.0

1.3

—

(40761539) Cells [Type] in Urine sediment by Light microscopy

0.00

0.0

1.2

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

0.0

1.3

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.4

—

(40758292) HTLV I+II Ab panel - Serum

0.00

0.0

1.5

—

(42868766) Dientamoeba fragilis DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.4

—

(3011544) Albumin [Mass/volume] in Pleural fluid

0.00

0.0

1.0

—

18.3

—

(3035457) Cefaclor IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3000213) Normetanephrine [Moles/time] in 24 hour Urine

0.00

0.0

1.3

—

1.9

—

(3005011) Chlamydia sp Ab [Titer] in Serum

0.00

0.0

1.5

—

(3014038) Collagen crosslinked N-telopeptide [Moles/volume] in Urine

0.00

0.0

1.8

—

(3004269) Kappa light chains [Mass/time] in 24 hour Urine

0.00

0.0

2.4

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

0.0

1.3

—

(3016616) Dehydroepiandrosterone sulfate (DHEA-S) [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

2.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_APPENDIX and mortality.

Females

Parameter	HR [95% CI]	p-value
CD2_BENIGN_APPENDIX	1.145 [0.93, 1.41]	0.206
Birth year	0.999 [0.99, 1.01]	0.73

During the follow-up period (1.1.1998 — 31.12.2019), 186 out of 979 females with CD2_BENIGN_APPENDIX died.

Males

Parameter	HR [95% CI]	p-value
CD2_BENIGN_APPENDIX	1.264 [1.04, 1.54]	0.019
Birth year	0.984 [0.97, 0.99]	0.003

During the follow-up period (1.1.1998 — 31.12.2019), 219 out of 743 males with CD2_BENIGN_APPENDIX died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_APPENDIX.

N-year risk	Females	Males
1	0.116%	0.274%
5	0.71%	1.536%
10	1.883%	3.573%
15	3.424%	6.429%
20	5.936%	10.78%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_APPENDIX – Benign neoplasm: Appendix

GWS hits: 2

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Appendix

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints