No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
362 |
4. Check minimum number of eventsNone |
362 |
5. Include endpointsNone |
362 |
6. Filter based on genotype QC (FinnGen only) |
362 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D12
- Name in latin
- Neoplasma benignum appendicis vermiformis
Similar endpoints
↥List of similar endpoints to Benign neoplasm: Appendix based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Appendix
- Benign neoplasm: Colon
- Benign neoplasm: Colon
- Benign neoplasm of colon, rectum, anus and anal canal
- Benign neoplasm of colon, rectum, anus and anal canal
Similar with less cases:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 2109 | 1194 | 910 |
Only index persons | 1983 | 1129 | 854 |
Unadjusted period prevalence (%) | |||
Whole population | 0.03 | 0.03 | 0.03 |
Only index persons | 0.04 | 0.04 | 0.03 |
Median age at first event (years) | |||
Whole population | 65.07 | 63.69 | 66.86 |
Only index persons | 64.78 | 63.24 | 66.80 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 362 | 199 | 163 |
Unadjusted period prevalence (%) | 0.07 | 0.07 | 0.07 |
Median age at first event (years) | 64.90 | 62.46 | 67.88 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 320
- Matched controls
- 3199
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_APPENDIX and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
CD2_BENIGN_APPENDIX | 1.145 [0.93, 1.41] | 0.206 |
Birth year | 0.999 [0.99, 1.01] | 0.73 |
During the follow-up period (1.1.1998 — 31.12.2019), 186 out of 979 females with CD2_BENIGN_APPENDIX died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
CD2_BENIGN_APPENDIX | 1.264 [1.04, 1.54] | 0.019 |
Birth year | 0.984 [0.97, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 219 out of 743 males with CD2_BENIGN_APPENDIX died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_APPENDIX.N-year risk | Females | Males |
---|---|---|
1 | 0.116% | 0.274% |
5 | 0.71% | 1.536% |
10 | 1.883% | 3.573% |
15 | 3.424% | 6.429% |
20 | 5.936% | 10.78% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_APPENDIX – Benign neoplasm: Appendix
GWS hits: 2