Benign neoplasm: Other and unspecified parts of small intestine

CD2_BENIGN_SMALL_INTESTINE_OTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D13.3&
  • Hospital discharge: ICD-9 2112
  • Hospital discharge: ICD-8 2112
  • Hospital discharge: excluded ICD-8 21121
  • Cause of death: ICD-10 D13.3&
  • Cause of death: ICD-9 2112
  • Cause of death: ICD-8 2112
  • Cause of death: excluded ICD-8 21121

2 out of 7 registries used, show all original rules.

556

4. Check minimum number of events

None

556

5. Include endpoints

None

556

6. Filter based on genotype QC (FinnGen only)

556

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D13
Name in latin
Neoplasma benignum partis aliae sive non specificatae intestini

Similar endpoints

List of similar endpoints to Benign neoplasm: Other and unspecified parts of small intestine based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3252 1858 1376
Only index persons 2890 1708 1182
Unadjusted period prevalence (%)
Whole population 0.05 0.05 0.04
Only index persons 0.06 0.06 0.05
Median age at first event (years)
Whole population 62.51 61.87 63.38
Only index persons 61.66 61.29 62.20

-FinnGen-

Key figures

All Female Male
Number of individuals 556 344 212
Unadjusted period prevalence (%) 0.11 0.12 0.09
Median age at first event (years) 60.31 58.29 63.59

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
507
Matched controls
5067
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D13.3
ICD-10 Finland
Benign neoplasm: Other and unspecified parts of small intestine
4503599627370496.0
323.0
480
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
12.6
142.1
387
1030
D13.2
ICD-10 Finland
Benign neoplasm: Duodenum
52.2
47.1
56
12
Z71.9
ICD-10 Finland
Counselling, unspecified
8.4
42.7
100
144
SPAT1236
SPAT
Informing family of child’s disability
14.8
41.6
71
55
UJF32
NOMESCO Finland
Coloscopy
3.7
38.3
233
957
Z51.88
ICD-10 Finland
Other specified medical care
17.3
37.6
60
39
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
13.9
37.2
65
53
Z26.9
ICD-10 Finland
Need for immunization against unspecified infectious disease
19.2
34.0
52
30
Z46.9
ICD-10 Finland
Fitting and adjustment of unspecified device
18.1
32.7
51
31
Z50.1
ICD-10 Finland
Other physical therapy
7.1
32.6
84
137
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
7.3
29.1
73
114
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
36.1
29.1
37
11
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
5.0
28.6
101
242
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.9
26.9
245
1248
WZC30
SPAT
NA
12.2
26.7
49
44
UJF92
NOMESCO Finland
Capsular endoscopy
10.7
25.1
49
50
JFB00
NOMESCO Finland
Partial resection of small intestine
13.3
25.1
44
36
Z01.7
ICD-10 Finland
Laboratory examination
4.1
25.0
109
319
Z01.8
ICD-10 Finland
Other specified special examinations
3.1
24.1
163
673
Z01.3
ICD-10 Finland
Examination of blood pressure
15.7
23.3
38
26
Z13.5
ICD-10 Finland
Special screening examination for eye and ear disorders
21.3
23.3
34
17
UJF30
NOMESCO Finland
Ileoscopy through colon
4.1
22.8
96
271
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
4.0
22.5
97
280
Z25.1
ICD-10 Finland
Need for immunization against influenza
5.4
22.2
70
146
Z12.3
ICD-10 Finland
Special screening examination for neoplasm of breast
21.9
21.5
31
15
C17.9
ICD-10 Finland
Malignant neoplasm: Small intestine, unspecified
52.4
21.3
25
5
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
3.7
21.1
100
312
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.4
20.3
78
201
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
13.3
20.2
35
28
JDA05
NOMESCO Finland
Endoscopic polypectomy in stomach or pylorus
37.4
20.0
25
7
XFE00
NOMESCO Finland
Epicardial ultrasonography
7.7
19.2
45
63
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
35.9
19.1
24
7
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
4.3
18.9
74
194
UJF02
NOMESCO Finland
Peroral enteroscopy
24.8
18.8
26
11
A02BC05
ATC
esomeprazole; systemic
2.3
18.0
262
1603
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
4.7
17.0
59
137
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.6
16.5
138
628
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.1
15.6
92
335
ZX120
NOMESCO Finland
Intravenous
3.5
15.5
78
253
SPAT1285
SPAT
Provision of consultation response
4.2
14.3
56
146
A02BC01
ATC
omeprazole; systemic
2.2
14.2
188
1067
D64.9
ICD-10 Finland
Anaemia, unspecified
3.0
14.1
87
324
OAB50
SPAT
NA
10.9
13.9
26
25
A02BA02
ATC
ranitidine; systemic
2.4
13.9
140
695
A02BC02
ATC
pantoprazole; systemic
2.1
13.7
363
2746
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.6
13.5
39
74
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.9
13.1
83
316
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
4.6
13.0
45
104
107
Kela drug reimbursment
Pernicious anaemia
7.8
12.9
29
39
B03BA03
ATC
hydroxocobalamin; parenteral
3.7
12.8
58
173
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.1
12.6
71
250
8240/3-C17.9
ICD-O-3
Neuroendocrine tumor, NOS, of small intestine, NOS
133.1
12.5
13
*
SPAT1324
SPAT
Screening procedure
2.7
12.4
95
405
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
12.0
12.4
22
19
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
5.7
12.3
35
65
K29.4
ICD-10 Finland
Chronic atrophic gastritis
5.9
12.3
34
61
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
4.4
12.3
44
106
XF404
NOMESCO Finland
Ambulatory ECG
3.0
12.3
75
279
UJD02
NOMESCO Finland
Gastroscopy
4.4
12.0
44
108
JDH05
NOMESCO Finland
Endoscopic polypectomy in duodenum
+∞
11.5
11
*
8240/3-C17.2
ICD-O-3
Neuroendocrine tumor, NOS, of ileum
+∞
11.5
11
*
XF402
NOMESCO Finland
ECG with work load test
2.7
11.5
83
340
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.4
11.5
107
507
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
20.6
11.2
16
8
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
10.7
161
943
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
10.5
159
930
R4110
NOMESCO Finland
Physiotherapy
2.0
10.5
165
983
K22.9
ICD-10 Finland
Disease of oesophagus, unspecified
23.9
10.3
14
6
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
10.1
126
680
H01CB02
ATC
octreotide; parenteral
40.9
10.0
12
*
JAH01
NOMESCO Finland
Laparoscopy
4.1
9.7
37
95
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.6
9.7
73
306
N02AX02
ATC
tramadol; systemic, rectal
1.8
9.7
235
1623
P01AB01
ATC
metronidazole; oral, rectal
1.9
9.7
215
1441
WZC00
SPAT
NA
4.4
9.7
34
81
K22.1
ICD-10 Finland
Ulcer of oesophagus
6.6
9.7
24
38
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.2
9.5
111
580
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.5
9.5
43
129
2112X
ICD-9 Finland
Benign neoplasm of other parts of digestive system, Duodenum, jejunum and ileum[NEOPLASMA BENIGNUM ALIUD INTESTINI TENUIS, DUOD INC]
+∞
9.4
9
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
5.3
9.2
27
53
J01MA12
ATC
levofloxacin; systemic
2.1
9.1
112
600
JN4BD
NOMESCO Finland
Extensive body CT
2.4
9.1
82
378
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
19.0
9.0
13
7
K29.3
ICD-10 Finland
Chronic superficial gastritis
4.2
8.9
33
83
C03CA01
ATC
furosemide; systemic
1.9
8.8
172
1096
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.8
8.8
55
208
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
8.7
49
171
JFA05
NOMESCO Finland
Endoscopic polypectomy in small intestine
50.9
8.7
10
*
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
5.7
8.7
24
44
R52.9
ICD-10 Finland
Pain, unspecified
2.7
8.5
60
242
A98
ICPC
Health maint/preventive medicine
0.5
8.5
394
4446
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.6
8.5
37
108
H02AB07
ATC
prednisone; oral
2.2
8.4
90
452
J01MA02
ATC
ciprofloxacin; systemic
1.8
8.4
211
1454
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
8.4
101
533
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
+∞
8.4
8
*
UKC02
NOMESCO Finland
Cystoscopy
2.1
8.3
97
508
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
17.5
8.1
12
7
K56.7
ICD-10 Finland
Ileus, unspecified
6.0
8.1
21
36
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.7
8.1
54
212
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
8.0
87
440
K92.1
ICD-10 Finland
Melaena
3.3
7.9
38
120
N02BE01
ATC
paracetamol; systemic, rectal
2.1
7.9
443
3894
B01AB05
ATC
enoxaparin; parenteral
1.8
7.9
177
1171
Z71.8
ICD-10 Finland
Other specified counselling
1.9
7.9
124
727
K29.1
ICD-10 Finland
Other acute gastritis
7.1
7.8
18
26
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
7.8
122
715
L01XE01
ATC
[U] imatinib; oral
45.7
7.7
9
*
3AC01
NOMESCO Finland
NA
12.1
7.6
13
11
189
Kela drug reimbursment
Imatinib
25.4
7.6
10
*
K50.0
ICD-10 Finland
Crohn disease of small intestine
7.3
7.5
17
24
Z12.4
ICD-10 Finland
Special screening examination for neoplasm of cervix
6.1
7.4
19
32
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
7.8
7.4
16
21
G44.2
ICD-10 Finland
Tension-type headache
2.2
7.4
76
373
U07.2
ICD-10 Finland
COVID-19, virus not identified
2.4
7.4
63
285
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
7.4
105
592
WX002
NOMESCO Finland
Sedation and analgesia
1.9
7.2
122
729
E34.0
ICD-10 Finland
Carcinoid syndrome
30.5
7.2
9
*
C17.2
ICD-10 Finland
Malignant neoplasm: Ileum
20.3
7.2
10
5
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
7.0
65
304
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
7.0
104
594
RD210
NOMESCO Finland
NA
6.5
7.0
17
27
N03AX16
ATC
pregabalin; oral
1.8
7.0
134
837
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
7.7
6.9
15
20
A02BC03
ATC
lansoprazole; oral
1.7
6.9
170
1149
K29.7
ICD-10 Finland
Gastritis, unspecified
3.8
6.9
27
73
K50.9
ICD-10 Finland
Crohn disease, unspecified
6.8
6.9
16
24
J45.1
ICD-10 Finland
Nonallergic asthma
2.6
6.8
48
196
JAH00
NOMESCO Finland
Laparotomy
4.4
6.8
23
54
WW500
NOMESCO Finland
Blood transfusion
3.4
6.8
31
95
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
6.8
154
1016
6402
FHL
Small bowel resection
40.6
6.8
8
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.7
6.7
46
183
R03AC03
ATC
terbutaline; inhalant
2.1
6.7
80
421
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
8.0
6.6
14
18
I20.90
ICD-10 Finland
Angina pectoris, unspecified
3.5
6.6
29
86
N06AB04
ATC
citalopram; systemic
1.8
6.6
122
750
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
3.6
6.5
27
77
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.4
6.4
52
229
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.5
6.4
28
83
M70.8
ICD-10 Finland
Other soft tissue disorders related to use, overuse and pressure
14.5
6.4
10
7
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
6.4
96
548
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
6.4
131
835
A07EA06
ATC
budesonide; oral, local oral
3.6
6.4
27
78
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.1
6.3
69
347
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.8
6.3
40
151
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
11.2
6.3
11
10
J01DB01
ATC
cefalexin; oral
1.7
6.3
406
3532
JN5ER
NOMESCO Finland
PET-CT of receptors in whole body
18.3
6.3
9
5
C17.1
ICD-10 Finland
Malignant neoplasm: Jejunum
27.0
6.2
8
*
JFA73
NOMESCO Finland
Excision of lesion of small intestine
27.0
6.2
8
*
K30
ICD-10 Finland
Functional dyspepsia
2.2
6.2
64
313
A03FA02
ATC
cisapride; oral, rectal
2.4
6.2
50
220
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
6.0
81
446
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.5
6.0
26
77
JN3AD
NOMESCO Finland
Abdominal CT examination
2.4
6.0
49
217

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
163
695
2.90
26.57
1.5
1.2
—
—
—
0
0
138
559
2.95
24.50
3.9
4.0
6.1
34.2
ug/l
1.22
118
474
166
765
2.67
22.87
3.8
2.2
11.0
12.7
umol/l
2.66
156
702
156
697
2.72
22.86
3.7
2.2
2.4
2.3
g/l
0.33
150
644
150
663
2.73
22.40
3.8
2.2
19.0
21.8
%
2.06
134
565
243
1357
2.40
22.04
5.0
3.2
0.4
0.5
e6/l
0.36
192
1023
238
1321
2.40
21.84
4.7
3.1
—
—
—
0
0
328
2128
2.32
20.50
7.4
6.1
8.4
8.7
%
0.76
310
1985
327
2122
2.31
20.38
7.2
5.8
2.8
2.8
%
0.02
311
1962
113
457
2.85
19.79
5.3
3.2
2.0
2.1
mmol/l
0.15
96
357
78
255
3.39
19.68
5.1
3.9
—
—
—
0
0
186
965
2.39
19.45
3.3
3.0
520.2
551.6
mosm/kgh2o
1.10
162
832
370
2558
2.33
19.44
9.1
6.1
11.6
11.3
umol/l
0.20
360
2418
184
956
2.38
19.13
4.4
3.9
58.0
254.1
ng/l
2.58
150
780
325
2139
2.25
19.10
7.3
5.7
57.4
57.8
%
0.19
304
1991
328
2171
2.25
18.95
7.3
6.0
27.5
27.2
%
0.21
310
2007
249
1477
2.24
18.85
5.1
3.3
28.4
107.1
e6/l
1.06
205
1142
114
475
2.76
18.80
5.2
3.2
—
—
—
0
0
125
546
2.66
18.79
2.9
2.6
11.1
8.3
umol/l
0.46
113
474
315
2059
2.22
18.67
7.2
5.8
0.7
0.7
%
0.29
298
1910
69
216
3.51
18.60
4.2
3.2
68.1
1794.6
u/ml
1.28
57
186
104
418
2.83
18.34
3.5
3.1
191.7
201.7
ng/l
0.11
96
388
272
1700
2.17
17.77
5.7
3.9
167.6
85.8
e6/l
0.40
209
1226
357
2491
2.21
17.49
9.2
6.2
1.2
1.2
mmol/l
0.18
333
2103
251
1532
2.16
17.30
5.9
5.6
—
—
—
0
0
305
2036
2.10
16.31
12.0
9.6
0.0
0.0
e9/l
0.41
246
1665
246
1530
2.09
15.75
3.8
2.3
59.5
56.4
u/l
0.58
236
1405
312
2133
2.05
15.27
7.3
4.4
34.9
35.2
g/l
0.27
300
1983
324
2253
2.05
15.04
6.9
5.7
0.6
0.6
e9/l
0.40
272
1929
49
141
3.71
14.93
4.3
4.9
—
—
—
0
0
325
2267
2.04
14.90
6.9
5.7
0.0
0.0
e9/l
0.00
273
1945
332
2340
2.04
14.71
7.6
5.9
0.2
0.2
e9/l
0.04
287
2039
302
2062
2.02
14.59
2.2
2.0
89.1
95.2
pmol/l
1.26
156
1022
150
791
2.23
14.50
3.9
3.0
2.5
2.6
e6/l
0.05
89
414
100
441
2.55
14.49
3.3
2.3
41.0
32.4
u/l
0.62
88
365
148
777
2.23
14.46
3.8
3.1
0.8
0.8
mmol/l
0.12
138
724
327
2304
2.02
14.36
7.0
5.7
1.9
1.9
e9/l
0.03
282
2014
299
2044
2.00
14.29
11.0
9.5
1.4
1.2
inr
0.86
45
570
237
1500
2.01
14.04
3.6
2.3
—
—
—
0
0
360
2646
2.02
13.77
12.0
9.1
4.2
4.1
e9/l
0.22
312
2307
178
1022
2.09
13.74
4.0
2.6
5.2
5.8
e6/l
0.20
166
918
33
75
4.61
13.73
3.1
2.6
—
—
—
0
0
204
1236
2.03
13.56
3.3
2.1
3.5
3.2
mg/l
0.56
184
1044
91
397
2.55
13.44
7.2
7.0
—
—
—
0
0
456
3683
2.32
13.31
11.8
7.5
86.0
79.6
u/l
1.53
443
3431
91
401
2.52
13.15
9.7
6.1
11.2
9.9
mmol/l
0.84
86
378
123
624
2.25
12.92
7.6
4.6
1.0
1.0
mmol/l
0.01
114
565
372
2802
1.99
12.82
6.2
4.6
6.9
6.7
mmol/l
1.24
355
2640
42
122
3.64
12.61
1.2
1.1
—
—
—
0
0
103
505
2.28
11.66
3.0
2.1
161.2
135.3
ug/g
0.37
89
389
92
443
2.29
10.82
2.5
2.0
0.2
0.2
g/l
1.34
83
415
273
1935
1.81
10.52
4.6
2.6
103.3
131.2
ug/l
2.34
261
1747
64
266
2.59
10.37
3.2
2.5
—
—
—
0
0
182
1152
1.86
10.06
2.7
2.3
—
—
—
0
0
184
1173
1.85
9.92
8.9
6.7
—
—
—
0
0
312
2332
1.77
9.77
4.9
4.0
0.0
0.0
estimate
0.50
19
412
82
393
2.27
9.72
4.3
3.4
123.5
82.9
ng/l
2.01
70
344
204
1352
1.80
9.63
5.9
4.2
—
—
—
0
0
296
2186
1.76
9.61
5.3
3.9
—
—
—
0
0
304
2296
1.71
8.81
4.8
4.0
0.0
0.0
estimate
0.00
18
425
305
2307
1.71
8.78
8.3
5.3
0.0
0.0
estimate
0.00
20
419
58
253
2.44
8.49
7.9
8.0
—
—
—
0
0
464
3992
1.98
8.29
32.6
16.6
37.3
39.2
%
3.28
300
2654
104
580
1.98
8.26
8.0
6.5
12.2
12.0
kpa
0.09
97
557
104
580
1.98
8.26
8.0
6.5
5.1
5.1
kpa
0.22
96
557
103
579
1.96
7.98
8.1
6.6
1.1
1.3
mmol/l
0.19
85
463
22
56
4.05
7.95
1.1
1.1
—
—
—
0
0
49
205
2.52
7.83
3.0
1.9
5.1
3.2
ug/l
0.27
39
182
158
1034
1.74
7.46
4.5
4.4
1.0
1.0
kg/l
2.35
73
140
93
520
1.95
7.29
8.1
6.7
95.0
95.6
%
0.32
87
500
435
3724
1.77
7.13
35.5
18.7
14.1
13.8
%
1.72
425
3645
14
27
5.29
7.00
1.2
1.9
14.3
14.0
%
—
6
11
389
3244
1.66
6.87
6.1
4.5
—
—
—
0
0
50
225
2.34
6.84
1.6
1.9
1.6
1.6
g/l
0.23
42
196
98
580
1.84
6.43
2.9
2.5
1.8
1.9
%
0.09
88
520
19
51
3.82
6.41
1.1
1.2
—
—
—
0
0
156
1063
1.65
6.19
2.5
1.6
1.0
1.2
mg/l
0.60
133
827
97
580
1.81
6.14
1.4
1.3
400.0
514.8
titre
0.32
17
131
16
40
4.09
5.93
1.9
1.9
1.2
1.1
e9/l
—
9
21
129
845
1.69
5.92
1.5
1.5
2.4
2.5
g/l
0.16
79
483
207
1525
1.57
5.89
4.7
3.7
7.4
7.4
ph
—
8
281
35
144
2.53
5.82
3.3
3.3
—
—
—
0
0
64
340
2.00
5.79
1.8
2.9
9.4
10.2
g/l
0.94
58
311
32
128
2.59
5.64
2.9
2.5
10.2
116.2
ug/min
2.76
26
74
49
243
2.11
5.33
1.5
1.3
—
—
—
0
0
145
1003
1.60
5.32
1.6
1.8
925.1
1217.0
nmol/l
4.76
122
739
499
4557
1.93
5.31
28.0
15.3
25.4
24.4
mg/l
0.29
432
3633
62
337
1.95
5.26
4.0
4.7
0.1
1.0
%
—
10
95
53
273
2.04
5.22
1.5
1.8
1.0
1.6
g/l
1.45
48
247
15
40
3.83
5.12
1.2
1.0
—
—
—
0
0
404
3503
1.56
5.12
5.5
4.3
14.2
13.2
mm/h
0.64
388
3207
221
1697
1.50
5.01
4.2
3.4
2.3
2.4
mmol/l
0.54
196
1463
34
149
2.37
4.97
1.4
1.5
279.8
276.6
ug/g
0.04
23
90
169
1231
1.54
4.90
1.7
1.6
20.3
21.2
nmol/l
0.40
155
1022
282
2285
1.48
4.84
7.7
5.4
1.2
1.2
mmol/l
1.36
259
2046
10
20
5.07
4.79
5.5
3.4
—
—
—
0
0
17
52
3.34
4.78
1.1
1.3
—
—
—
0
0
34
152
2.32
4.76
1.3
1.2
—
—
—
0
0
35
161
2.25
4.60
1.8
1.6
—
—
—
0
0
87
547
1.70
4.60
1.5
1.3
—
—
—
0
0
63
362
1.83
4.52
4.5
4.6
0.0
0.2
%
3.28
12
115
166
1225
1.51
4.47
5.6
3.6
—
—
—
0
0
48
254
1.97
4.41
3.1
3.0
0.3
0.2
e6/l
0.14
48
244
66
388
1.80
4.40
4.3
4.4
0.2
0.9
%
3.97
12
130
84
530
1.69
4.38
2.3
1.7
—
—
—
0
0
195
1498
1.46
4.26
6.3
4.1
—
—
—
0
0
19
68
2.86
4.16
1.1
1.2
—
66.5
—
0
6
204
1598
1.44
3.97
3.7
3.3
—
—
—
0
0
54
311
1.82
3.87
9.9
7.8
94.1
94.2
%
0.03
54
306
131
946
1.50
3.85
5.8
4.9
—
—
—
0
0
87
1266
0.63
3.85
4.5
4.3
0.0
0.0
estimate
0.00
19
408
103
706
1.56
3.84
2.6
2.0
—
—
—
0
0
15
49
3.12
3.83
1.1
1.2
—
—
—
0
0
71
445
1.68
3.80
1.5
1.4
—
—
—
0
0
201
1582
1.42
3.77
3.1
3.1
1895.6
1295.9
ng/l
0.64
182
1357
26
115
2.32
3.77
1.3
1.2
—
656.0
—
0
5
15
380
0.38
3.65
4.6
4.1
—
—
—
0
0
401
3575
1.44
3.57
4.6
4.0
14.5
14.9
pmol/l
3.16
377
3187
17
63
2.75
3.52
1.1
1.2
2.4
4.8
u/ml
—
7
24
8
14
5.78
3.35
1.4
1.6
—
—
—
0
0
146
1105
1.44
3.34
3.5
3.9
—
—
—
0
0
68
437
1.63
3.31
2.2
2.7
72.5
71.7
e9/l
0.06
50
340
145
1102
1.43
3.23
1.7
1.7
76562982.1
6455717.2
pmol/l
0.44
128
883
10
28
3.62
3.21
1.1
1.1
—
—
—
0
0
159
1232
1.41
3.17
3.5
2.7
7964.7
8288.6
umol/l
0.02
143
1038
48
284
1.76
3.17
1.3
1.3
—
—
—
0
0
16
61
2.67
3.16
1.0
1.0
—
—
—
0
0
129
966
1.44
3.11
1.3
1.2
0.6
1.8
u/ml
1.65
40
254
31
160
1.99
3.11
1.3
1.4
1.3
1.2
g/l
0.82
26
151
83
569
1.54
3.09
1.7
1.4
—
—
—
0
0
20
88
2.32
2.97
3.4
2.6
—
—
—
0
0
8
17
4.76
2.93
4.7
3.8
—
—
—
0
0
18
76
2.41
2.92
1.5
1.5
—
—
—
0
0
83
592
1.47
2.57
1.2
1.3
—
—
—
0
0
12
44
2.77
2.56
1.8
2.1
—
—
—
0
0
505
4801
1.57
2.43
31.6
17.8
139.7
139.7
mmol/l
0.09
497
4672
10
34
2.98
2.42
5.5
3.1
—
—
—
0
0
506
4815
1.57
2.40
31.6
17.9
3.9
4.0
mmol/l
2.49
496
4681
0
67
0.00
2.40
0.0
2.0
—
89.5
—
0
67
126
981
1.37
2.39
3.8
3.0
2.5
2.5
mmol/l
0.48
109
868
11
40
2.79
2.38
1.4
1.7
—
—
—
0
0
454
4238
1.39
2.34
5.7
4.9
1.9
2.3
mu/l
0.61
436
3808
57
385
1.54
2.30
1.6
1.5
—
—
—
0
0
10
36
2.81
2.21
1.2
1.3
—
—
—
0
0
68
481
1.47
2.21
1.8
1.5
—
—
—
0
0
23
123
1.91
2.14
2.0
1.6
3705.2
17877.3
e6/l
1.89
18
89
60
420
1.48
2.06
1.5
1.4
—
—
—
0
0
6
15
4.03
2.04
4.3
4.5
43.7
48.9
%
—
6
15
21
111
1.93
2.03
2.2
2.2
—
—
—
0
0
8
26
3.11
2.02
1.4
1.2
—
—
—
0
0
495
4718
1.45
2.01
25.4
14.5
—
—
—
0
0
38
244
1.60
1.93
1.1
1.3
—
—
—
0
0
55
385
1.48
1.90
1.5
1.4
—
—
—
0
0
221
1916
1.25
1.84
2.4
2.2
—
—
—
0
0
20
108
1.88
1.84
1.2
1.2
—
—
—
0
0
7
23
3.07
1.80
1.1
1.7
—
—
—
0
0
505
4853
1.44
1.73
16.2
11.0
26.0
24.6
u/l
1.08
499
4657
13
61
2.16
1.72
1.2
1.3
—
—
nmol/l
—
0
0
100
792
1.32
1.69
1.3
1.3
28.3
37.5
iu/ml
0.59
26
260
19
104
1.86
1.69
1.8
2.7
33.4
34.6
umol/l
0.06
14
86
11
49
2.27
1.64
1.0
1.1
—
—
—
0
0
16
84
1.93
1.61
3.4
1.7
58.5
57.8
%
0.04
16
84
6
20
3.02
1.58
1.3
1.1
6.0
7.0
mmol/l
—
6
20
5
15
3.35
1.52
1.0
1.1
—
—
—
0
0
11
51
2.18
1.51
5.4
3.1
—
—
—
0
0
6
21
2.88
1.51
1.2
3.0
435.0
1007.9
u/ml
—
6
21
94
756
1.29
1.43
1.4
1.3
12.0
13.4
u/ml
0.07
44
271
48
349
1.41
1.40
8.7
4.2
—
—
—
0
0
220
1952
1.21
1.39
4.3
4.0
26.3
54.9
ng/l
1.01
160
1450
45
328
1.40
1.31
1.2
1.2
—
—
—
0
0
26
170
1.56
1.28
2.7
2.2
354.5
534.9
ug/l
0.25
26
159
17
100
1.72
1.24
1.5
1.3
61.3
61.5
mmol/l
—
10
85
8
36
2.24
1.24
1.3
1.2
—
—
—
0
0
453
4341
1.24
1.15
7.9
6.3
41.2
40.4
mmol/mol
1.09
437
3984
20
127
1.60
1.13
1.1
1.6
—
—
—
0
0
7
31
2.27
1.10
1.3
1.5
9.7
9.9
%
—
7
31
5
21
2.39
1.09
1.2
1.3
—
—
—
0
0
5
21
2.39
1.09
7.2
5.5
—
—
—
0
0
81
665
1.26
1.07
32.4
25.4
1.3
1.3
inr
—
5
91
10
52
1.94
1.06
1.2
2.3
—
—
—
0
0
9
46
1.97
1.04
1.1
1.9
—
—
—
0
0
11
60
1.85
1.03
2.7
1.4
14.6
16.1
ug/l
0.39
11
60
16
250
0.63
1.03
1.2
1.4
—
—
—
0
0
45
346
1.33
0.99
4.0
4.5
0.2
0.5
%
—
6
93
14
85
1.66
0.95
1.1
1.3
135.9
243.3
miu/ml
—
5
36
9
51
1.78
0.95
1.3
1.1
—
—
—
0
0
25
176
1.44
0.92
2.4
3.8
51.8
90.0
mg/l
0.49
25
139
25
176
1.44
0.92
2.4
3.8
49.3
47.1
mg/l
0.03
25
140
512
5004
1.29
0.88
40.2
22.5
91.2
91.5
fl
0.66
505
4921
512
5005
1.29
0.87
40.3
22.6
243.9
247.6
e9/l
0.64
500
4864
512
5005
1.29
0.87
40.1
22.5
30.3
30.3
pg
0.47
505
4922
512
5006
1.29
0.85
40.2
22.6
4.3
4.4
e12/l
5.19
498
4845
512
5006
1.29
0.85
40.2
22.6
6.9
6.7
e9/l
0.86
497
4844
512
5008
1.28
0.83
40.5
22.7
129.3
133.6
g/l
8.36
507
4922
11
65
1.71
0.83
1.1
1.1
—
—
—
0
0
11
65
1.71
0.83
1.1
1.3
—
—
—
0
0
14
89
1.59
0.82
1.1
1.1
69.7
23.0
u/l
0.49
14
72
161
1450
1.16
0.81
4.2
3.1
—
—
—
0
0
29
216
1.36
0.80
1.3
1.2
—
—
—
0
0
151
1355
1.16
0.79
5.6
5.2
2.7
3.3
ug/l
0.28
136
1199
38
297
1.30
0.77
2.4
3.0
4.1
4.0
e9/l
0.09
28
219
0
28
0.00
0.76
0.0
1.3
—
—
—
0
0
354
3372
1.14
0.75
4.2
4.1
—
—
—
0
0
36
281
1.30
0.74
1.0
1.2
166.9
128.2
iu/ml
0.21
16
112
55
454
1.23
0.73
1.6
2.5
4.4
6.9
ug/l
1.34
49
395
468
4549
1.18
0.73
5.2
4.9
6.2
6.0
mmol/l
2.39
448
4090
39
309
1.28
0.73
2.1
2.6
—
11.2
—
0
8
10
60
1.68
0.72
6.2
2.8
—
—
—
0
0
7
41
1.72
0.70
1.9
1.3
—
—
—
0
0
5
27
1.86
0.68
1.0
1.0
—
—
—
0
0
42
513
0.80
0.66
4.3
4.0
—
—
—
0
0
12
78
1.55
0.66
1.3
1.2
—
—
—
0
0
18
130
1.40
0.62
1.5
4.1
—
—
—
0
0
14
197
0.70
0.60
1.7
2.1
—
—
—
0
0
23
175
1.33
0.59
1.6
1.4
—
—
—
0
0
8
53
1.52
0.58
1.4
1.6
—
—
—
0
0
8
53
1.52
0.58
1.4
1.6
—
—
—
0
0
8
53
1.52
0.58
1.4
1.6
—
—
—
0
0
8
53
1.52
0.58
1.4
1.6
—
—
—
0
0
33
403
0.81
0.54
4.5
3.6
—
—
—
0
0
9
61
1.48
0.54
1.0
1.2
—
—
—
0
0
6
39
1.54
0.53
1.3
1.1
—
—
—
0
0
38
316
1.22
0.51
4.0
2.9
—
—
—
0
0
9
65
1.39
0.51
1.1
2.1
31.6
32.2
pg
—
9
65
45
382
1.19
0.49
1.7
2.4
—
—
—
0
0
117
1278
0.89
0.49
1.7
1.6
1.4
1.3
mmol/l
0.67
101
1053
29
235
1.25
0.49
3.3
3.4
—
—
—
0
0
7
109
0.64
0.49
2.3
2.4
—
—
—
0
0
11
77
1.44
0.46
1.5
1.5
465.6
277.1
mu/l
0.93
11
71
5
31
1.62
0.43
1.4
1.2
0.1
1.3
u/ml
—
5
17
12
87
1.39
0.42
1.3
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
5.9
—
26.2
—
0
15
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
11
79
1.40
0.41
1.5
1.7
39.6
43.1
nmol/l
0.16
11
73
31
260
1.20
0.40
1.3
1.3
—
—
—
0
0
166
1561
1.09
0.40
4.0
3.9
16.9
8.3
mg/mmol
0.76
109
959
10
137
0.72
0.39
1.3
1.3
—
—
—
0
0
19
151
1.27
0.39
13.1
11.9
—
—
—
0
0
5
76
0.65
0.36
1.8
3.2
2.6
4.3
e9/l
—
5
76
24
199
1.22
0.35
2.8
2.9
—
—
—
0
0
5
80
0.62
0.35
1.8
3.7
54.4
58.9
%
—
5
80
444
4358
1.09
0.35
4.4
4.2
1.3
1.3
mmol/l
0.74
419
3911
142
1508
0.92
0.34
3.4
3.1
6.7
7.0
mmol/l
0.57
125
1239
12
91
1.33
0.34
1.0
1.5
—
—
—
0
0
6
45
1.34
0.34
1.0
1.1
—
—
—
0
0
84
772
1.10
0.33
2.7
3.1
0.8
0.8
ug/l
0.07
66
525
6
89
0.67
0.33
4.8
2.3
—
—
—
0
0
11
83
1.33
0.32
1.8
1.6
—
—
—
0
0
41
365
1.13
0.28
1.4
1.4
—
—
—
0
0
8
66
1.22
0.27
1.5
1.3
—
—
—
0
0
5
72
0.69
0.26
1.2
1.3
13.2
11.5
u/l
—
5
57
12
96
1.26
0.24
4.2
3.4
—
—
—
0
0
5
39
1.28
0.23
1.2
1.1
—
—
—
0
0
5
40
1.25
0.22
1.0
1.1
—
1.0
—
0
7
5
41
1.22
0.22
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
6.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
13
109
1.20
0.18
1.8
1.6
1.9
5.2
iu/l
—
5
34
153
1478
1.05
0.17
3.5
3.2
2261.0
184.5
mg/l
1.47
98
919
5
69
0.72
0.17
1.0
1.3
—
—
—
0
0
5
69
0.72
0.17
1.0
1.3
—
—
—
0
0
5
69
0.72
0.17
1.0
1.3
—
—
—
0
0
19
168
1.14
0.16
1.1
1.1
—
—
—
0
0
18
202
0.89
0.14
1.7
1.5
—
—
—
0
0
469
4654
1.05
0.13
5.5
5.3
2.6
2.7
mmol/l
0.69
444
4218
18
199
0.90
0.11
14.1
4.3
—
—
—
0
0
115
1117
1.04
0.11
1.4
1.3
—
—
—
0
0
12
136
0.88
0.11
1.2
1.1
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
6
55
1.09
0.09
1.2
1.5
—
—
—
0
0
6
56
1.07
0.08
1.0
1.1
—
—
—
0
0
454
4514
1.03
0.08
4.8
4.6
1.4
1.5
mmol/l
4.51
431
4083
29
274
1.06
0.07
1.3
1.4
—
44.2
—
0
15
11
100
1.10
0.05
3.9
2.5
15.8
15.7
%
0.03
11
45
456
4544
1.02
0.04
4.8
4.7
4.5
4.6
mmol/l
1.44
435
4140
13
135
0.96
0.00
1.8
2.1
12.6
13.0
mg/l
0.07
13
124
18
175
1.03
0.00
3.8
2.9
0.4
0.2
g/l
0.30
13
55
45
445
1.01
0.00
1.7
1.6
—
—
—
0
0
15
151
0.99
0.00
1.6
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
7
73
0.96
0.00
1.3
1.2
—
—
—
0
0
9
91
0.99
0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
6
64
0.94
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
0.00
4.0
7.1
6.1
6.6
mmol/l
—
5
47
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
6
65
0.92
0.00
3.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
5.2
—
0.3
—
0
5

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_SMALL_INTESTINE_OTH and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_SMALL_INTESTINE_OTH 1.31 [1.14, 1.51] < 0.001
Birth year 0.997 [0.99, 1.01] 0.472

During the follow-up period (1.1.1998 — 31.12.2019), 383 out of 1599 females with CD2_BENIGN_SMALL_INTESTINE_OTH died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_SMALL_INTESTINE_OTH 1.317 [1.13, 1.54] < 0.001
Birth year 0.986 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 352 out of 1120 males with CD2_BENIGN_SMALL_INTESTINE_OTH died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_SMALL_INTESTINE_OTH.

N-year risk Females Males
1 0.148% 0.234%
5 0.834% 1.488%
10 2.109% 3.955%
15 3.974% 7.041%
20 6.921% 11.979%

Relationships between endpoints

Index endpoint: CD2_BENIGN_SMALL_INTESTINE_OTH – Benign neoplasm: Other and unspecified parts of small intestine

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data