This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
42 |
4. Check minimum number of eventsNone |
42 |
5. Include endpointsNone |
42 |
6. Filter based on genotype QC (FinnGen only) |
40 |
Control definitions (FinnGen only)
- Control exclude
- Q17_OTHER_CONGEN_MALFO
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Noonan syndrome
based on the number of shared cases.
Similar with more cases:
- Other specified congenital malformation syndromes affecting multiple systems
- Exclusion endpoint for clefts
- Clefts and syndromes for tooth agenesis exclusion, including avohilmo
- Other congenital malformations
- Other congenital malformations
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 40 | 21 | 19 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 14.69 | 24.89 | 3.42 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
23
55
8.03
10.55
3.3
13.2
31.75
31.57
s
0.04
23
55
16
18
13.57
9.08
3.6
10.3
131.63
147.89
%
0.54
16
18
14
20
9.90
6.94
3.7
14.9
2.64
3.11
g/l
0.81
14
20
15
26
8.35
6.63
4.7
19.4
90.67
91.50
%
0.06
15
26
20
74
4.25
4.97
3.1
3.5
—
—
—
0
0
7
6
13.62
4.45
2.1
5.5
94.71
91.33
%
—
7
6
18
68
3.88
4.25
3.2
5.8
0.61
1.84
mg/l
—
8
56
27
135
3.80
4.19
3.1
3.3
—
—
—
0
0
11
34
4.01
3.01
3.0
9.6
198.27
404.56
u/l
0.62
11
34
33
224
3.20
2.76
18.0
7.2
112.43
99.46
ml/min/173m2
2.36
23
180
10
36
3.32
2.33
2.4
10.1
105.30
104.94
mmol/l
—
10
36
5
10
5.50
2.13
1.6
1.3
—
—
—
0
0
19
105
2.48
2.08
2.9
4.0
—
—
—
0
0
0
36
0.00
1.20
0.0
1.6
—
—
—
0
0
5
20
2.69
1.18
1.2
1.4
—
—
—
0
0
9
47
2.16
1.11
3.0
7.1
5.80
5.83
umol/l
—
9
40
28
219
1.84
0.99
10.2
6.4
77.89
104.97
u/l
1.93
28
210
6
31
2.09
0.88
2.0
2.3
28.17
27.92
u/l
—
6
26
10
59
1.91
0.85
5.0
10.8
6.98
5.72
kpa
—
10
59
10
64
1.74
0.66
18.8
14.0
24.30
24.64
mmol/l
—
10
64
0
20
0.00
0.62
0.0
1.5
—
—
—
0
0
0
21
0.00
0.62
0.0
1.8
—
—
—
0
0
6
34
1.89
0.62
1.8
1.8
2.36
2.44
mmol/l
—
6
29
0
22
0.00
0.61
0.0
1.4
—
—
—
0
0
0
23
0.00
0.60
0.0
1.1
—
1.60
—
0
17
8
58
1.47
0.45
23.4
8.8
23.88
24.18
mmol/l
—
8
58
32
349
0.65
0.44
4.3
4.2
—
—
—
0
0
0
16
0.00
0.42
0.0
1.2
—
—
—
0
0
0
16
0.00
0.42
0.0
1.3
—
—
—
0
0
5
34
1.53
0.42
2.2
2.3
4.26
11.99
iu/l
—
5
28
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
7
51
1.45
0.34
3.3
11.2
24.71
23.45
mmol/l
—
7
51
11
138
0.73
0.32
1.6
2.0
—
—
—
0
0
12
95
1.37
0.30
3.7
2.7
2.33
2.38
mmol/l
0.71
12
90
5
42
1.22
0.22
2.6
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
0.56
—
0
5
0
13
0.00
0.21
0.0
1.5
—
1.35
—
0
8
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
5
44
1.15
0.10
2.6
1.6
—
—
—
0
0
12
129
0.90
0.04
1.5
1.8
0.40
3.80
u/ml
—
5
22
11
106
1.05
0.00
6.8
2.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
62.60
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
28.89
—
0
9
0
8
0.00
-0.00
0.0
1.3
—
41.45
—
0
8
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
11.46
—
0
9
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1255.20
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
0.27
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
58
1.04
-0.00
2.3
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_NOONAN – Noonan syndrome
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).