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Follicular adenocarcinoma of thyroid gland, including Hilmo

Endpoint Browser PheWeb

C3_THYROID_FOLLICULAR_WIDE

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — C73.92&
  • Hospital discharge: ICD-9 — 193B
  • Cause of death: ICD-10 — C73.92&
  • Cause of death: ICD-9 — 193B
  • Cancer registry: Topography ICD-O-3 — C73
  • Cancer registry: Morphology ICD-O-3 — 833[0-2]|8335
  • Cancer registry: Behaviour codes — 3

3 out of 7 registries used, show all original rules.

386

4. Check minimum number of events

None

386

5. Include endpoints

None

386

6. Filter based on genotype QC (FinnGen only)

373

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 373 246 127
Unadjusted period prevalence (%) 0.08 0.09 0.06
Median age at first event (years) 53.79 50.63 59.92

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
386
Matched controls
3860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C73.92
ICD-10 Finland
Follicular carcinoma of the thyroid gland
+∞
307.7
354
*
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
134.0
307.7
191
28
104
Kela drug reimbursment
Thyroid insufficiency
60.7
307.7
277
155
EP1AE
NOMESCO Finland
Neck ultrasound examination
51.9
295.6
189
70
H03AA01
ATC
levothyroxine sodium; systemic
125.6
268.2
371
635
8330/3-C73.9
ICD-O-3
Follicular carcinoma, NOS, of thyroid gland
+∞
266.7
224
*
BAA60
NOMESCO Finland
Total thyroidectomy
60.3
226.5
132
33
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
63.7
193.3
110
24
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
343.3
170.4
161
8
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
169.7
150
*
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
315.0
160.6
153
8
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
+∞
134.4
121
*
ZX114
NOMESCO Finland
Intramuscular
57.8
124.0
71
15
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
39.3
95.7
60
18
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
29.0
79.8
55
22
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
14.3
79.0
78
67
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.7
63.8
237
843
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
+∞
61.1
57
*
JN5AQ
NOMESCO Finland
SPECT of thyroid metastasis with low-dose CT
+∞
60.0
56
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
55.6
52
*
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
+∞
55.6
52
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
24.7
55.1
40
18
130
Kela drug reimbursment
Malignant tumour
+∞
54.5
51
*
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
16.6
53.7
47
32
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
+∞
50.1
47
*
4CJ01, ,
NOMESCO Finland
+∞
46.8
44
*
WZC00
NOMESCO Finland
Treatment plan or consultation
4.4
44.9
186
678
BA1NN
NOMESCO Finland
I-131 dose capsel measurement
+∞
36.0
34
*
Z51.88
ICD-10 Finland
Other specified medical care
11.9
34.3
36
33
XX3DW
NOMESCO Finland
Time consuming IT work
7.4
34.1
53
81
WX402
NOMESCO Finland
General anaesthesia
4.2
32.8
113
350
8290/3-C73.9
ICD-O-3
Oxyphilic adenocarcinoma of thyroid gland
+∞
30.6
29
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
29.6
28
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
162.2
29.1
30
*
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
84.2
28.2
31
*
H02AB02
ATC
dexamethasone; systemic
26.2
27.6
38
16
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
27.4
26
*
WW200
NOMESCO Finland
Immunization
10.4
27.1
31
32
JN4AD
NOMESCO Finland
Body CT examination
6.7
26.6
45
75
115
Kela drug reimbursment
Breast cancer
+∞
26.3
25
*
19399
ICD-8 Finland
Malignant neoplasm of thyroid gland
+∞
26.3
25
*
PJA12
NOMESCO Finland
Sentinel node biopsy
243.9
22.9
23
*
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
127.6
22.8
24
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
48.2
22.7
27
6
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
22.1
21
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
22.1
21
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.8
21.4
174
875
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
20.0
19
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
110.8
19.8
21
*
A04AA02
ATC
granisetron; systemic, transdermal
210.3
19.7
20
*
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
210.3
19.7
20
*
JN4BD
NOMESCO Finland
Extensive body CT
5.8
19.4
37
69
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.1
19.1
99
387
Z51.5
ICD-10 Finland
Palliative care
7.0
19.0
30
46
T71
ICPC
Malignant neoplasm thyroid
+∞
18.9
18
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
18.9
18
*
WB223
NOMESCO Finland
Demanding adjuvant hormone therapy of malignancy
+∞
18.9
18
*
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
17.3
18.6
29
18
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
17.8
17
*
HA1AA
NOMESCO Finland
X-ray mammography
6.9
17.7
28
43
WF002
NOMESCO Finland
Radical radiotherapy
44.2
17.5
21
5
GD1AD
NOMESCO Finland
Thorax CT examination
5.4
17.0
35
70
106
Kela drug reimbursment
Hypoparathyroidism
66.4
16.9
19
*
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
62.7
15.9
18
*
WZC30
NOMESCO Finland
Teaching
3.3
15.5
66
228
JN6AD
NOMESCO Finland
CT of torso and neck
30.0
15.3
20
7
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
14.8
112
527
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
6.7
14.3
23
36
A11CC03
ATC
alfacalcidol; systemic
12.1
14.0
25
22
NK6AN
NOMESCO Finland
Total body bone isotope imaging
78.0
13.7
15
*
JN5SN, ,
NOMESCO Finland
+∞
13.6
13
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
13.6
13
*
1930B
ICD-9 Finland
Malignant neoplasm of thyroid gland[CARCINOMA FOLLICULARE THYREOIDEAE]
+∞
13.6
13
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
51.8
12.9
15
*
A03FA01
ATC
metoclopramide; systemic, rectal
2.8
12.9
74
301
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.3
12.6
26
52
XX9AQ
NOMESCO Finland
Supplementary SPECT-CT or additional scan
+∞
12.6
12
*
8340/3-C73.9
ICD-O-3
Papillary carcinoma, follicular variant of thyroid gland
+∞
12.6
12
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
12.6
12
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
12.6
12
*
N02AA05
ATC
oxycodone; systemic
2.7
11.7
70
290
L03AA13
ATC
pegfilgrastim; parenteral
67.0
11.7
13
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
23.8
11.7
16
7
198
Kela drug reimbursment
Sorafenib
+∞
11.5
11
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
11.5
11
*
323
Kela drug reimbursment
Sorafenib
+∞
11.5
11
*
116
Kela drug reimbursment
Prostate cancer
+∞
11.5
11
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
11.5
11
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
123.5
11.5
12
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
123.5
11.5
12
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
5.2
11.4
24
49
WX704
NOMESCO Finland
Intubation
3.8
11.2
36
103
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
11.1
180
1141
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
5.1
10.9
23
47
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
18.5
10.8
16
9
L02BG04
ATC
letrozole; oral
9.6
10.6
21
23
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
113.0
10.5
11
*
E04.8
ICD-10 Finland
Other specified nontoxic goitre
113.0
10.5
11
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
10.5
10
*
2506
FHL
Thyroidectomy
+∞
10.5
10
*
8341/3-C73.9
ICD-O-3
Papillary microcarcinoma of thyroid gland
+∞
10.5
10
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
10.5
10
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
10.5
10
*
8335/3-C73.9
ICD-O-3
Follicular carcinoma, minimally invasive of thyroid gland
+∞
10.5
10
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
10.5
10
*
GD6AD
NOMESCO Finland
CT of chest and neck
33.5
10.4
13
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
41.2
10.0
12
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
9.7
87
434
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
18.1
9.5
14
8
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
9.4
9
*
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
11.9
9.1
16
14
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
37.6
9.1
11
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.5
9.0
22
51
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.0
8.9
26
69
L02BA01
ATC
tamoxifen; oral
51.2
8.7
10
*
A11CC02
ATC
dihydrotachysterol; oral
28.2
8.5
11
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
8.4
8
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
8.4
8
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
8.4
8
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
8.4
8
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
8.4
8
*
L02BG03
ATC
anastrozole; oral
+∞
8.4
8
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.8
8.4
44
170
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
14.9
8.3
13
9
Z31.5
ICD-10 Finland
Genetic counselling
4.2
8.2
22
55
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
25.6
7.6
10
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
7.4
7.6
17
24
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
81.6
7.4
8
*
BAA99
NOMESCO Finland
Other operation on thyroid gland
81.6
7.4
8
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.1
7.4
32
111
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
7.3
7
*
1508
Kela drug reimbursment
Lenvatinib
+∞
7.3
7
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
+∞
7.3
7
*
C73.93
ICD-10 Finland
Anaplastic thyroid carcinoma (thyroid)
+∞
7.3
7
*
PJD91
NOMESCO Finland
Excision of lymph nodes in neck, 1 to 2 areas in total
+∞
7.3
7
*
3019
Kela drug reimbursment
Lenvatinib
+∞
7.3
7
*
C739, ,
ICD-10 Finland
+∞
7.3
7
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
7.3
7
*
BA1AQ
NOMESCO Finland
Thyroid SPECT with low dose CT
+∞
7.3
7
*
L01BC06
ATC
capecitabine; oral
+∞
7.3
7
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
7.3
7
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
7.3
7
*
A04AA01
ATC
ondansetron; systemic, rectal
4.5
7.0
17
39
JN4CD
NOMESCO Finland
Very extensive body CT
8.5
6.9
14
17
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
17.1
6.8
10
6
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
6.6
6.7
16
25
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
71.0
6.4
7
*
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
71.0
6.4
7
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
71.0
6.4
7
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.3
6.4
50
234
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
6.3
6
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
6.3
6
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
6.3
6
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
6.3
6
*
1930A
ICD-9 Finland
Malignant neoplasm of thyroid gland[CARCINOMA PAPILLARE THYREOIDEAE]
+∞
6.3
6
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
+∞
6.3
6
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
6.3
6
*
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
+∞
6.3
6
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
6.3
6
*
JN5AN
NOMESCO Finland
Total body isotope imaging
+∞
6.3
6
*
ZXA00
NOMESCO Finland
Right side
1.8
6.2
105
651
M05BX04
ATC
denosumab; parenteral
3.0
6.2
27
94
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.5
6.1
39
166
E03.89
ICD-10 Finland
Other specified hypothyroidism
3.3
6.1
23
73

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
246
180
35.92
294.78
8.6
3.5
4.62
4.53
pmol/l
0.47
241
156
97
34
37.77
149.61
1.5
1.2
—
—
—
0
0
99
74
17.65
109.92
1.4
1.3
—
—
—
0
0
230
814
5.52
61.78
8.2
3.0
7.40
7.40
ph
0.33
70
133
298
1382
6.07
55.54
11.7
5.4
1.21
1.22
mmol/l
1.76
244
1197
280
1243
5.56
54.81
9.3
5.0
1.21
1.22
mmol/l
1.31
269
1122
214
911
4.03
40.54
4.3
1.9
2.31
2.35
mmol/l
4.60
201
766
92
232
4.89
34.99
2.2
3.7
45.09
76.15
ng/l
9.48
80
206
86
208
5.03
34.36
6.3
2.5
1.20
1.23
mmol/l
2.39
81
178
88
221
4.86
33.55
1.6
1.1
—
—
—
0
0
40
46
9.59
32.48
1.9
2.4
—
—
—
0
0
358
2476
7.15
28.96
11.8
4.0
17.63
14.78
pmol/l
43.67
343
2264
193
992
2.89
23.21
2.7
1.7
—
—
—
0
0
222
1268
2.77
21.20
2.5
2.2
—
—
—
0
0
55
139
4.45
20.36
3.3
1.5
4.22
2.53
ug/l
0.44
44
106
211
1298
2.38
15.54
2.6
2.3
81.08
77.32
nmol/l
1.34
196
1149
199
1201
2.36
15.22
4.3
3.4
36.47
36.10
g/l
0.53
188
1111
151
810
2.42
15.10
2.5
1.9
—
—
—
0
0
223
1428
2.33
14.66
6.8
3.6
10.97
10.92
umol/l
0.03
212
1345
304
2250
2.65
14.13
9.8
5.1
77.45
74.58
u/l
0.80
291
2067
362
2952
4.64
14.10
16.1
4.8
2.88
2.29
mu/l
0.26
346
2720
238
1643
2.17
12.05
8.6
6.2
3.93
4.18
e9/l
1.05
204
1432
242
1742
2.04
10.21
4.3
3.9
6.45
6.69
mmol/l
0.78
228
1614
189
1310
1.87
8.27
13.0
13.7
1.22
1.29
inr
0.61
71
395
27
79
3.60
8.10
1.7
2.0
5.14
7.30
iu/l
—
10
29
68
342
2.20
7.33
3.1
4.6
1.09
1.02
mmol/l
1.16
61
302
118
741
1.85
6.79
1.5
1.4
—
—
—
0
0
52
249
2.26
6.29
3.8
3.1
—
—
—
0
0
41
182
2.40
5.89
4.2
4.1
0.60
0.20
%
—
10
44
42
190
2.36
5.79
4.3
4.2
0.09
0.05
%
0.17
11
41
118
780
1.74
5.56
2.5
2.8
—
—
—
0
0
43
201
2.28
5.50
4.5
4.1
0.50
0.74
%
0.49
12
52
9
8
11.48
5.31
1.9
1.5
11.85
12.47
ug/l
—
9
8
40
184
2.31
5.31
4.3
4.3
0.22
0.03
%
—
9
37
261
2138
1.68
5.30
4.3
3.7
—
—
—
0
0
119
814
1.67
4.85
4.7
3.6
0.00
0.00
estimate
-0.00
50
270
95
613
1.73
4.80
2.4
2.3
3.96
5.87
e6/l
1.56
81
550
177
1340
1.59
4.77
11.7
7.7
0.00
0.00
e9/l
0.42
155
1103
7
5
14.22
4.59
5.0
1.2
64.86
59.20
nmol/l
—
7
5
92
599
1.70
4.47
2.7
2.6
542.14
535.53
mosm/kgh2o
0.12
73
512
355
3239
2.20
4.41
18.3
13.4
139.91
139.77
mmol/l
0.54
348
3138
7
6
11.85
4.29
4.0
1.0
17.29
14.83
u/ml
—
7
6
347
3148
2.01
4.25
18.9
11.3
21.05
21.23
mg/l
0.03
281
2394
355
3248
2.16
4.22
18.8
13.4
3.92
3.97
mmol/l
2.81
345
3147
122
866
1.60
4.20
4.2
3.1
—
—
—
0
0
101
685
1.64
4.18
4.1
3.5
—
—
—
0
0
142
1053
1.55
4.02
3.0
3.5
61.68
126.52
e6/l
1.09
106
737
16
53
3.11
4.01
2.8
1.3
—
—
—
0
0
112
795
1.58
3.81
2.6
2.8
0.40
0.42
e6/l
0.04
86
604
23
97
2.46
3.72
1.7
2.4
10830.24
2911.83
u/l
—
5
37
121
884
1.54
3.60
2.7
2.9
79.43
117.73
e6/l
0.19
94
680
358
3318
2.09
3.58
18.8
10.8
—
—
—
0
0
42
231
1.92
3.55
1.2
1.2
62.32
122.42
iu/ml
1.21
17
104
190
1531
1.47
3.49
4.4
3.4
0.00
0.00
estimate
0.50
57
290
12
32
3.84
3.42
1.3
1.0
—
—
—
0
0
192
1557
1.46
3.37
4.4
3.5
0.00
0.01
estimate
0.50
52
266
119
881
1.51
3.29
3.5
3.7
—
—
—
0
0
6
7
8.68
3.27
1.2
1.0
—
—
—
0
0
17
66
2.65
3.26
1.6
1.3
76.12
57.67
pmol/l
0.47
17
66
306
2737
1.57
3.20
21.1
13.5
14.76
14.70
%
0.07
301
2693
8
17
4.78
2.93
1.1
1.1
162.38
167.63
mmol/24h
—
8
17
187
1537
1.42
2.92
5.7
4.7
0.00
0.00
estimate
-0.00
51
269
17
73
2.39
2.69
4.7
1.4
28.21
31.38
mg/l
0.22
12
60
17
73
2.39
2.69
4.7
1.4
34.27
45.80
mg/l
0.77
12
62
122
944
1.43
2.61
2.4
2.1
100.41
57.01
u/l
0.90
105
868
13
50
2.66
2.56
2.1
2.3
—
—
—
0
0
244
2132
1.39
2.51
4.5
4.0
—
—
—
0
0
15
63
2.44
2.49
2.7
3.0
7.41
7.42
ph
0.35
15
56
183
1529
1.37
2.46
5.7
5.5
0.17
0.19
e9/l
1.41
157
1357
43
269
1.67
2.42
9.6
3.9
—
—
—
0
0
9
216
0.40
2.39
1.1
1.5
—
—
—
0
0
148
1204
1.37
2.32
3.7
3.5
24.61
68.49
ng/l
0.83
100
818
13
53
2.50
2.30
1.8
3.3
3.83
4.21
e9/l
0.23
13
53
13
53
2.50
2.30
1.8
3.7
60.69
57.36
%
0.46
13
53
30
172
1.81
2.28
4.8
4.1
7.39
7.42
ph
—
10
18
166
1378
1.36
2.28
7.2
5.6
—
—
—
0
0
23
121
1.96
2.26
5.8
8.7
—
—
—
0
0
180
1517
1.35
2.22
5.7
5.3
1.68
1.88
e9/l
2.94
158
1361
176
1479
1.35
2.21
5.6
5.2
0.55
0.57
e9/l
0.48
152
1292
8
24
3.38
2.19
3.1
2.5
—
—
—
0
0
48
318
1.58
2.17
1.9
2.3
6.90
6.26
umol/l
0.10
41
273
30
175
1.77
2.17
4.9
4.1
5.43
5.15
kpa
1.03
30
169
6
14
4.34
2.16
2.5
1.3
616.17
844.57
e6/l
—
6
14
176
1488
1.34
2.09
5.6
5.2
0.04
0.04
e9/l
0.79
151
1302
6
15
4.05
2.04
1.0
1.1
—
—
—
0
0
355
3371
1.66
1.99
12.3
8.3
24.06
25.11
u/l
0.74
346
3241
88
672
1.40
1.98
7.3
4.6
—
—
—
0
0
44
297
1.54
1.85
1.4
1.3
—
—
—
0
0
30
184
1.68
1.85
3.3
1.3
—
—
—
0
0
257
2324
1.32
1.77
4.4
4.1
12.33
11.40
mm/h
0.40
237
2134
149
1254
1.31
1.76
3.7
3.2
6.32
5.88
ph
0.73
11
92
6
18
3.37
1.75
1.0
1.3
—
—
—
0
0
8
30
2.70
1.73
1.1
1.6
—
—
—
0
0
7
24
2.95
1.73
1.0
1.1
—
—
—
0
0
14
68
2.10
1.72
2.9
2.9
25.21
24.88
mmol/l
0.09
14
68
51
363
1.47
1.69
2.5
2.2
21.94
22.89
%
0.15
40
316
11
49
2.28
1.65
3.4
2.8
—
—
—
0
0
92
740
1.32
1.48
2.6
2.2
3.87
3.04
mg/l
1.22
80
621
5
16
3.15
1.44
1.0
1.3
—
—
—
0
0
159
1379
1.26
1.42
3.1
2.7
98.43
96.27
ug/l
0.06
148
1268
154
1334
1.26
1.38
6.0
5.3
0.69
0.69
%
0.04
142
1236
48
352
1.42
1.38
1.6
1.7
—
—
—
0
0
160
1396
1.25
1.34
6.7
5.6
8.59
8.30
%
0.58
148
1300
93
760
1.29
1.33
3.2
2.2
357.06
10003.37
umol/l
4.43
79
668
37
260
1.47
1.33
1.5
3.2
2.43
1.87
mmol/l
0.57
29
210
9
43
2.12
1.31
1.3
1.4
—
—
—
0
0
41
297
1.43
1.27
2.1
2.2
1.76
1.66
%
0.34
36
265
40
290
1.42
1.24
5.1
6.4
1.30
1.49
mmol/l
0.19
32
234
162
1430
1.23
1.19
6.3
5.3
26.53
28.19
%
1.14
150
1338
14
79
1.80
1.18
1.2
1.1
—
—
—
0
0
158
1392
1.23
1.18
6.1
5.2
2.57
2.94
%
1.48
146
1293
110
939
1.24
1.10
3.1
2.9
—
—
—
0
0
9
46
1.98
1.04
1.0
1.2
—
—
—
0
0
364
3540
1.50
1.04
28.2
16.7
40.51
40.33
%
0.25
341
3299
364
3540
1.50
1.04
28.4
16.7
252.74
252.16
e9/l
0.06
356
3455
10
53
1.91
1.02
1.3
1.5
—
—
—
0
0
159
1421
1.20
1.00
5.9
5.1
59.43
57.47
%
1.16
147
1329
364
3543
1.48
0.99
28.3
16.7
4.54
4.51
e12/l
0.49
355
3450
24
165
1.48
0.99
3.3
7.1
24.88
24.69
mmol/l
0.15
24
159
364
3544
1.48
0.98
28.2
16.7
6.39
6.63
e9/l
1.74
356
3448
0
29
0.00
0.98
0.0
1.1
—
3.27
—
0
6
10
54
1.87
0.97
1.3
1.2
10.81
13.58
u/l
—
10
47
31
227
1.40
0.94
1.2
1.2
—
—
—
0
0
86
727
1.24
0.94
1.5
1.5
20.66
21.27
nmol/l
0.15
79
627
6
27
2.24
0.94
2.3
1.2
33.33
33.59
pg
—
6
27
6
28
2.16
0.92
1.2
1.1
—
—
—
0
0
6
30
2.02
0.87
1.0
1.2
—
—
—
0
0
6
30
2.02
0.87
2.8
1.2
—
—
—
0
0
25
179
1.42
0.86
2.0
1.7
—
—
—
0
0
34
258
1.35
0.85
4.8
6.7
95.81
94.85
%
0.36
34
249
8
45
1.79
0.84
7.3
3.4
—
—
—
0
0
6
31
1.95
0.84
3.2
2.4
13.33
13.27
%
—
6
31
17
113
1.53
0.83
15.4
7.4
—
—
—
0
0
49
394
1.28
0.82
1.5
1.8
—
—
—
0
0
24
173
1.41
0.81
2.9
4.7
—
—
—
0
0
83
713
1.21
0.78
5.2
3.5
1.02
1.02
kg/l
0.11
19
99
0
27
0.00
0.77
0.0
1.3
—
—
—
0
0
24
175
1.40
0.76
2.8
2.4
—
—
—
0
0
6
34
1.78
0.76
1.3
2.1
15.25
113.70
u/ml
—
6
34
50
410
1.25
0.73
2.7
1.8
29.93
29.56
s
0.14
50
395
16
109
1.49
0.72
1.1
1.2
—
—
—
0
0
5
92
0.54
0.68
1.2
1.9
26.80
20.60
s
—
5
83
16
111
1.46
0.67
6.6
4.8
26.17
25.07
mmol/l
0.51
16
104
87
982
0.85
0.63
3.3
3.0
7.17
7.47
mmol/l
0.27
76
824
85
961
0.85
0.63
4.2
3.7
15.21
6.52
mg/mmol
0.67
51
579
80
908
0.85
0.62
3.6
3.1
991.29
262.76
mg/l
0.37
50
562
8
49
1.65
0.62
1.0
1.1
—
—
—
0
0
217
2046
1.14
0.60
3.5
2.9
45.08
42.03
u/l
0.27
197
1913
21
157
1.36
0.60
2.0
2.7
0.07
0.15
e6/l
0.61
21
150
0
21
0.00
0.60
0.0
1.5
—
0.92
—
0
21
62
533
1.19
0.59
1.7
1.8
—
—
—
0
0
0
22
0.00
0.59
0.0
18.1
—
1450.27
—
0
22
0
22
0.00
0.59
0.0
14.4
—
857.36
—
0
22
28
351
0.78
0.58
1.3
1.4
—
—
—
0
0
26
203
1.30
0.57
4.2
2.6
—
—
—
0
0
18
133
1.37
0.56
6.1
4.1
—
—
—
0
0
9
63
1.44
0.52
1.2
2.5
—
—
—
0
0
75
664
1.16
0.52
1.8
1.7
518.30
7286411.05
pmol/l
0.50
64
549
40
336
1.21
0.50
1.8
1.6
—
—
—
0
0
52
449
1.18
0.49
2.0
2.8
6.83
2.79
e6/l
0.44
30
238
35
291
1.22
0.48
1.7
1.4
—
—
—
0
0
7
49
1.44
0.46
1.6
1.5
—
—
—
0
0
14
103
1.37
0.46
1.6
4.7
—
—
—
0
0
5
85
0.58
0.46
1.0
1.1
—
—
—
0
0
7
50
1.41
0.45
1.6
1.8
73.80
65.23
%
—
7
50
36
304
1.20
0.44
1.5
1.5
—
—
—
0
0
307
3145
0.88
0.41
4.2
4.3
1.45
1.50
mmol/l
1.59
281
2917
0
15
0.00
0.41
0.0
20.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
2.6
—
69.00
—
0
11
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
1.55
—
0
19
20
161
1.26
0.38
1.3
1.3
—
—
—
0
0
108
1161
0.90
0.37
2.8
2.9
—
—
—
0
0
15
116
1.30
0.37
1.4
1.7
—
—
—
0
0
80
731
1.12
0.36
5.3
3.7
2.43
1.93
ug/l
0.64
70
658
6
41
1.47
0.36
1.3
1.2
—
—
—
0
0
6
42
1.44
0.35
2.5
1.3
—
—
—
0
0
22
264
0.82
0.34
1.0
1.1
—
—
—
0
0
6
45
1.34
0.34
2.5
1.3
0.48
0.54
nmol/l
—
6
40
6
87
0.68
0.33
1.2
1.2
588.67
431.65
mg/l
—
6
79
296
3024
0.91
0.31
3.8
3.9
1.34
1.27
mmol/l
1.03
272
2779
46
411
1.14
0.30
3.8
2.6
0.77
0.73
ug/l
0.13
30
261
24
203
1.19
0.30
5.9
6.9
—
—
—
0
0
48
431
1.13
0.30
1.2
1.2
—
—
—
0
0
288
2943
0.92
0.29
5.7
5.7
39.29
39.65
mmol/mol
0.32
264
2743
28
322
0.86
0.28
1.5
1.4
—
—
—
0
0
11
140
0.78
0.28
1.0
1.1
—
—
—
0
0
68
626
1.10
0.28
1.5
1.3
2.09
2.46
g/l
1.35
51
363
311
3165
0.91
0.27
4.3
4.4
4.66
4.68
mmol/l
0.14
288
2945
12
96
1.26
0.25
1.1
1.3
—
—
—
0
0
9
76
1.19
0.25
1.7
1.7
—
—
—
0
0
31
275
1.14
0.24
1.7
2.5
4.47
6.03
ug/l
0.38
26
241
5
40
1.25
0.22
2.8
1.3
—
—
nmol/l
—
0
0
14
116
1.21
0.22
1.3
1.4
—
—
—
0
0
14
116
1.21
0.22
1.2
1.5
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
18
154
1.18
0.21
1.1
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
5
43
1.16
0.21
1.8
1.2
—
—
—
0
0
5
43
1.16
0.21
1.0
1.6
—
—
—
0
0
17
145
1.18
0.21
1.0
1.1
—
6.20
—
0
5
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
14
117
1.20
0.21
1.3
1.4
—
—
—
0
0
54
581
0.92
0.20
2.2
1.8
1514.11
1223.71
nmol/l
0.93
39
441
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
74
697
1.08
0.20
4.2
3.4
—
—
—
0
0
21
184
1.15
0.19
1.6
1.4
—
—
—
0
0
14
118
1.19
0.19
1.3
1.5
—
—
—
0
0
16
137
1.18
0.19
1.3
2.3
0.69
0.63
%
0.33
16
137
28
308
0.90
0.16
1.4
1.6
—
—
—
0
0
8
69
1.16
0.16
1.3
1.1
—
—
—
0
0
8
70
1.15
0.16
3.4
3.8
1.68
1.54
mg/l
—
8
63
319
3226
0.94
0.16
4.8
4.9
2.81
2.76
mmol/l
0.45
292
2997
6
77
0.78
0.15
5.0
3.1
—
—
—
0
0
6
78
0.77
0.15
1.2
1.2
4.12
3.80
mmol/l
—
6
71
9
78
1.16
0.15
1.9
2.5
—
—
—
0
0
45
421
1.08
0.15
1.4
1.6
—
—
—
0
0
16
141
1.14
0.14
1.3
2.3
1.01
1.20
%
0.74
16
141
12
103
1.17
0.14
4.4
2.7
0.29
0.17
g/l
—
5
32
13
115
1.13
0.10
1.2
1.4
—
—
—
0
0
13
115
1.13
0.10
1.4
1.6
—
—
—
0
0
5
45
1.11
0.10
1.0
1.2
—
—
—
0
0
5
47
1.06
0.09
1.0
1.2
—
—
—
0
0
57
592
0.96
0.08
1.5
1.3
16.09
37.67
iu/ml
3.57
23
191
9
102
0.88
0.06
1.1
1.5
—
—
—
0
0
23
217
1.06
0.06
1.3
1.4
—
46.62
—
0
16
10
109
0.92
0.04
1.5
1.2
—
—
—
0
0
313
3117
1.02
0.03
4.5
4.4
5.86
5.92
mmol/l
0.42
287
2858
25
241
1.04
0.02
3.4
2.8
—
—
—
0
0
45
440
1.03
0.02
1.4
1.4
270.00
505.96
titre
—
8
114
16
168
0.95
0.02
3.6
3.3
—
—
—
0
0
127
1259
1.01
0.02
1.9
2.0
98.01
96.21
pmol/l
0.15
64
638
66
667
0.99
0.01
1.4
1.6
0.82
1.04
mg/l
0.63
53
500
73
723
1.01
0.01
1.3
1.3
1.91
1.70
u/ml
0.10
25
205
41
404
1.02
0.00
2.0
2.4
140.29
105.69
ug/g
0.32
33
304
57
564
1.01
0.00
1.4
1.3
19.96
12.62
u/ml
0.25
25
221
29
288
1.01
0.00
1.4
1.4
—
—
—
0
0
85
848
1.00
0.00
1.8
1.6
1.43
1.38
mmol/l
0.23
71
727
23
225
1.02
0.00
1.4
1.4
—
—
—
0
0
59
586
1.01
0.00
3.5
3.8
266.82
340.05
ng/l
0.11
50
449
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
1.34
—
0
9
5
49
1.02
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
20.30
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.0
—
5.59
—
0
7
8
86
0.93
-0.00
4.8
4.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
335.40
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
42.0
—
119.63
—
0
8
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: C3_THYROID_FOLLICULAR_WIDE – Follicular adenocarcinoma of thyroid gland, including Hilmo

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).