No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
82 |
4. Check minimum number of eventsNone |
82 |
5. Include endpointsNone |
82 |
6. Filter based on genotype QC (FinnGen only) |
82 |
Control definitions (FinnGen only)
- Control exclude
- F5_PERSOBEH
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- F63-F69
- Name in latin
- Perturbationes praeferentiae sexualis
Similar endpoints
↥List of similar endpoints to
Disorders of sexual preference
based on the number of shared cases.
Similar with more cases:
- Disorders of adult personality and behaviour
- Psychiatric diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 921 | 154 | 755 |
| Only index persons | 675 | 116 | 559 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.00 | 0.02 |
| Only index persons | 0.02 | 0.00 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 31.68 | 28.72 | 32.05 |
| Only index persons | 29.04 | 23.76 | 30.13 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 82 | 11 | 71 |
| Unadjusted period prevalence (%) | 0.03 | 0.00 | 0.03 |
| Median age at first event (years) | 32.88 | 28.29 | 33.59 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 77
- Matched controls
- 768
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F65.4
ICD-10 Finland
Paedophilia
+∞
17.3
16
*
N05AH03
ATC
olanzapine; systemic
44.1
16.7
20
6
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
19.9
16.5
25
18
30200
ICD-8 Finland
Sexual deviation, Homosexuality
+∞
12.9
12
*
30299
ICD-8 Finland
Sexual deviation, Unspecified
+∞
10.7
10
*
N03AG01
ATC
valproic acid; systemic, rectal
11.8
9.4
17
18
N06AB04
ATC
citalopram; systemic
6.0
9.2
28
67
N05AA02
ATC
levomepromazine; systemic
16.8
9.1
14
10
N06AB03
ATC
fluoxetine; oral
7.8
9.0
21
35
N05AX08
ATC
risperidone; systemic
11.9
7.9
14
14
30041
ICD-8 Finland
Neuroses, Depressiva
50.3
7.9
9
*
F61.0
ICD-10 Finland
Mixed personality disorders
88.2
7.6
8
*
30188
ICD-8 Finland
Personality disorders, Alia definita
+∞
7.4
7
*
N05CD07
ATC
temazepam; oral
6.2
7.3
20
41
N05AF03
ATC
chlorprothixene; systemic
33.5
7.3
9
*
N05AX12
ATC
aripiprazole; systemic
18.8
6.9
10
6
N05AB03
ATC
perphenazine; systemic, rectal
18.8
6.9
10
6
N05BA04
ATC
oxazepam; oral
4.5
6.8
26
78
F29
ICD-10 Finland
Unspecified nonorganic psychosis
16.1
6.6
10
7
T36
ICD-10 Finland
Poisoning by systemic antibiotics
10.7
6.6
12
13
N05AN01
ATC
lithium; oral
75.9
6.5
7
*
N05AD01
ATC
haloperidol; systemic
20.1
6.4
9
5
N05AA01
ATC
chlorpromazine; systemic, rectal
29.3
6.4
8
*
F65.9
ICD-10 Finland
Disorder of sexual preference, unspecified
+∞
6.3
6
*
E9509
ICD-8 Finland
Suicide and self-inflicted poisoning by solid or liquid substances, Other and unspecified solid and liquid substances
+∞
6.3
6
*
F65.0
ICD-10 Finland
Fetishism
+∞
6.3
6
*
Mortality – FinRegistry
↥Association
Association between endpoint F5_SEXPREF and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have F5_SEXPREF.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: F5_SEXPREF – Disorders of sexual preference
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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