Benign neoplasm: Ciliary body

CD2_BENIGN_CILIARY

stomach neoplasm: A benign or malignant neoplasm involving the stomach.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D31.4& Cause of death: ICD-10 — D31.4& 2 out of 7 registries used, show all original rules.	95
4. Check minimum number of events None	95
5. Include endpoints None	95
6. Filter based on genotype QC (FinnGen only)	95

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D31
Name in latin: Neoplasma benignum corporis ciliaris

NAME	CD2_BENIGN_CILIARY
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D314
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D314
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Ciliary body based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Benign neoplasm: Ciliary body

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	562	332	227
Only index persons	535	325	210
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	61.29	61.05	61.90
Only index persons	61.53	61.28	61.92

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	95	51	44
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	63.77	58.91	69.39

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
84: Matched controls
838

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D31.4

ICD-10 Finland

Benign neoplasm: Ciliary body

+∞

120.9

XCD10

NOMESCO Finland

Electrophysiological examination of eye

85.4

41.8

CH2S4

NOMESCO Finland

Photography of iris

+∞

25.3

XCK10

NOMESCO Finland

Photography of fundus of eye

11.0

16.9

D31.3

ICD-10 Finland

Benign neoplasm: Choroid

34.3

16.6

CH3S4

NOMESCO Finland

Photography of iridocorneal angle

+∞

11.7

CK2L4

NOMESCO Finland

Wide-field/panoramic imaging of ocular fundus

125.0

10.7

Z01.0

ICD-10 Finland

Examination of eyes and vision

5.4

10.1

CK2X4

NOMESCO Finland

Optical coherence tomography (OCT) of ocular fundus

5.1

6.4

C69.40

ICD-10 Finland

Malignant tumor of ciliary body without histology

+∞

6.3

C69.30

ICD-10 Finland

Malignant tumor of the chorioidea without histology

+∞

6.3

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(42870588) Differential panel, method unspecified - Blood

251

2.51

4.58

5.1

5.3

—

(3045142) Bone marrow Pathology biopsy report

6.52

2.40

1.0

1.3

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

4.33

1.84

1.6

1.5

—

(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma

0.00

1.76

0.0

4.7

—

228.9

—

(3023520) Reticulocytes [#/volume] in Blood

2.14

1.64

1.7

2.4

74.7

73.8

e9/l

—

(3002030) Lymphocytes/100 leukocytes in Blood

362

1.66

1.62

4.7

5.5

25.1

27.0

0.39

330

(3030467) Casts [#/volume] in Urine by Automated count

226

1.71

1.59

4.2

3.0

0.4

e6/l

0.09

170

(3002582) Erythrocytes [#/volume] in Urine

246

1.67

1.53

4.0

3.2

15.6

294.2

e6/l

0.55

191

(3020564) Creatinine [Moles/volume] in Serum or Plasma

829

2.63

1.51

19.5

17.9

78.7

79.9

umol/l

0.21

829

(42529406) Shigella sp [Presence] in Stool by Culture

2.62

1.48

1.0

1.3

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.62

1.48

1.0

1.3

—

(36304419) Bacteria [Presence] in Urine

225

1.64

1.38

4.1

3.0

—

(3009542) Hematocrit [Volume Fraction] of Blood

694

1.82

1.36

20.4

15.5

41.0

40.1

0.68

494

(3002256) Pathology report gross observation

1.89

1.35

1.3

1.2

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

337

1.57

1.32

2.1

2.2

82.0

78.2

nmol/l

0.34

292

(1761868) Lipid panel - Serum or Plasma

282

1.58

1.30

3.1

3.2

—

(3021589) Normoblasts [#/volume] in Blood

338

1.56

1.30

10.2

10.5

0.0

e9/l

0.50

288

(1002224) Polysomnography panel

2.39

1.20

1.0

1.2

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

252

1.54

1.15

3.5

3.4

875.9

1021.4

ng/l

0.25

214

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

444

1.50

1.12

3.0

2.9

—

(40761511) CBC panel - Blood by Automated count

817

2.05

1.09

14.5

14.2

—

(3001019) Free T4 and TSH panel - Serum or Plasma

2.21

1.08

1.4

2.0

—

(21494755) Public health laboratory ask at order entry panel

1.94

1.08

1.2

1.5

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

369

1.48

1.06

3.9

5.9

1.2

mmol/l

0.07

329

(40768797) Stomach Pathology biopsy report

133

1.64

1.05

1.2

1.3

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

133

1.64

1.05

3.7

2.8

1.3

2.4

e6/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

347

0.65

1.02

3.8

4.0

14.5

39.7

ng/l

2.01

249

(3032080) INR in Blood by Coagulation assay

333

1.47

1.02

15.4

8.1

1.3

1.2

inr

0.12

108

(3044889) 12 lead EKG panel

572

1.50

1.01

4.5

4.2

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

460

1.46

1.01

10.8

9.8

4.0

4.1

e9/l

0.17

402

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.99

0.0

1.2

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

0.00

0.99

0.0

1.3

—

2.4

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

784

1.80

0.94

16.6

15.0

21.4

22.1

mg/l

0.06

620

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

2.22

0.93

1.0

1.3

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

813

1.83

0.92

19.5

17.6

140.0

139.7

mmol/l

0.41

794

(3018418) pH of Serum or Plasma

254

1.46

0.91

4.1

7.4

—

(3001604) Monocytes [#/volume] in Blood

377

1.43

0.91

5.3

5.7

0.6

e9/l

0.33

329

(3006315) Basophils [#/volume] in Blood

378

1.42

0.89

5.3

5.7

0.0

e9/l

0.54

332

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.89

0.88

1.9

1.7

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

755

1.63

0.84

18.8

14.4

76.5

77.9

ml/min/173m2

0.27

620

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

203

1.46

0.83

1.5

1.7

1.0

1.3

mmol/l

2.49

167

(3037121) Protein [Mass/volume] in Urine

0.00

0.80

0.0

3.3

—

0.2

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

585

1.42

0.79

4.6

4.2

15.0

14.8

pmol/l

0.28

517

(3018095) Leukocytes [#/volume] in Urine

279

1.40

0.79

4.9

3.8

19.3

40.3

e6/l

1.03

206

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

0.00

0.78

0.0

1.3

—

3.3

—

(3013115) Eosinophils [#/volume] in Blood

395

1.38

0.77

6.7

5.7

0.2

e9/l

0.07

350

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

280

1.40

0.77

4.1

4.8

1.4

2.0

ug/l

1.45

246

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

715

1.51

0.76

5.3

4.9

1.8

1.9

mu/l

0.33

639

(40761536) Microorganisms panel - Urine sediment

1.66

0.76

4.5

3.4

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

771

1.61

0.76

4.9

4.7

1.4

1.5

mmol/l

0.27

699

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

794

1.67

0.75

5.3

5.2

2.7

mmol/l

0.08

723

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.86

0.74

1.0

1.3

—

(3008898) HLA-B27 [Presence]

2.05

0.74

1.0

1.1

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

320

1.37

0.74

3.1

2.5

119.8

130.6

ug/l

0.13

291

(3019198) Lymphocytes [#/volume] in Blood

388

1.36

0.73

5.3

5.8

2.6

1.9

e9/l

0.30

348

(3013707) Erythrocyte sedimentation rate by Westergren method

583

1.36

0.67

4.3

4.2

8.3

11.8

mm/h

1.46

526

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

313

0.73

0.64

3.3

3.7

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

778

1.53

0.63

4.9

4.7

4.6

mmol/l

0.35

717

(3025941) Bacteria identified in Stool by Culture

1.62

0.62

1.0

1.3

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

405

1.32

0.62

5.0

6.7

1.2

mmol/l

0.02

336

(3004588) Protein electrophoresis panel - Serum or Plasma

1.59

0.61

1.6

2.2

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.61

0.0

1.3

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.51

0.59

2.1

1.9

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.59

0.0

5.6

—

26.4

—

(40768804) Tissue Pathology biopsy report

341

1.30

0.56

2.1

2.0

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

293

1.31

0.56

3.7

3.2

—

(3000492) Spirometry study

1.50

0.55

1.2

1.6

—

(3022145) Colonoscopy Study observation

1.48

0.54

1.0

1.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.48

0.54

2.1

1.8

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

110

0.61

0.52

1.4

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.47

0.49

2.9

3.6

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.56

0.49

2.4

4.0

4.3

4.5

pmol/l

—

(3042936) Bacteria identified in Isolate by Culture

120

0.64

0.49

1.5

1.7

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.46

0.47

2.1

1.5

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

140

1.35

0.46

4.0

2.7

1.0

e6/l

—

(3000494) Fungus identified in Specimen by Culture

0.62

0.45

1.7

1.3

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.61

0.44

1.2

1.5

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

759

1.34

0.42

4.3

4.2

1.1

1.3

mmol/l

1.58

683

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

379

0.80

0.42

2.9

4.0

—

(40768800) Prostate Pathology biopsy report

0.00

0.41

0.0

1.1

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.41

0.0

1.3

—

200.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.36

0.41

1.1

1.6

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.41

0.0

3.2

—

1.5

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.41

0.0

3.2

—

8.7

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

749

1.33

0.41

5.9

6.4

38.9

40.5

mmol/mol

1.38

699

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.40

0.0

1.2

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

171

1.29

0.40

1.6

1.7

1.5

mg/l

0.09

148

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.39

0.0

1.2

—

(40760892) CBC W Ordered Manual Differential panel - Blood

182

1.27

0.37

5.5

5.3

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.39

0.35

1.7

1.3

—

(40758558) Short blood count panel - Blood

194

1.24

0.34

10.8

7.8

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.35

0.29

1.4

1.7

—

(3019309) Folate [Moles/volume] in Red Blood Cells

160

1.23

0.28

2.8

1.7

1133.9

1348.6

nmol/l

0.34

115

(3012544) pH of Venous blood

0.69

0.27

3.8

3.3

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

770

1.25

0.27

5.0

4.8

5.9

6.0

mmol/l

0.45

702

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

124

1.25

0.26

2.1

2.0

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

0.70

0.25

1.2

1.4

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.37

0.24

1.8

1.2

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

289

1.16

0.23

3.0

3.4

2.3

2.4

mmol/l

0.45

254

(3000330) Specific gravity of Urine by Test strip

1.30

0.23

2.0

3.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

100

0.78

0.22

4.6

7.7

—

(43055225) Phosphorylated tau 181 [Mass/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.21

0.0

1.1

—

36.0

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.21

0.0

1.3

—

(3000242) Tau protein [Mass/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

271.5

—

(3042810) Amyloid beta 42 peptide [Mass/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

503.3

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.21

0.0

1.2

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.21

0.0

1.4

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.21

0.0

4.9

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.21

0.0

1.3

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

3.1

—

3.9

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.4

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.6

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.21

0.0

1.4

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

3.1

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.4

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.4

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

13.0

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.4

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.21

0.0

1.4

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.4

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.21

0.0

3.8

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.21

0.0

4.3

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

3.2

—

162.0

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.4

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.4

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

3.1

—

105.6

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.4

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.4

—

(3029937) Albumin [Presence] in Urine by Test strip

217

0.84

0.21

3.3

4.0

0.0

estimate

0.00

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(40768441) Liver Pathology biopsy report

0.00

0.21

0.0

1.0

—

(3051014) Leukocytes [#/area] in Urine sediment by Automated count

0.00

0.21

0.0

1.5

—

1.8

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.21

0.0

1.2

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

0.21

0.0

2.1

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.24

0.20

4.3

4.6

25.2

mmol/l

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.20

0.0

1.2

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.20

0.0

1.1

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

184

0.84

0.19

2.0

2.2

—

(4035726)

1.24

0.18

1.4

1.3

—

(3023368) Bacteria identified in Blood by Culture

216

1.15

0.18

5.5

4.5

—

(3044640) Blood type and Crossmatch panel - Blood

254

0.88

0.17

2.1

2.3

—

(3037467) Urinalysis macro (dipstick) panel - Urine

535

1.11

0.15

3.9

4.0

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

316

1.12

0.15

2.3

2.0

86.7

95.6

pmol/l

0.48

156

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

0.81

0.15

1.1

1.9

1.1

1.5

—

(3026008) Bacteria identified in Urine by Culture

230

0.89

0.13

3.1

2.7

—

(3009261) Glucose [Presence] in Urine by Test strip

390

1.09

0.11

2.9

3.6

0.0

estimate

0.00

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.04

0.09

2.0

1.5

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

224

1.10

0.09

3.0

4.3

29.5

22.5

—

105

(3022621) pH of Urine by Test strip

1.14

0.09

2.3

1.9

—

(3003694) ABO and Rh group [Type] in Blood

205

0.91

0.09

1.4

—

(3005719) IgG [Mass/volume] in Serum or Plasma

0.77

0.08

4.4

2.1

10.7

9.5

g/l

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.10

0.08

1.7

1.4

—

(3035350) Ketones [Presence] in Urine by Test strip

384

1.07

0.08

3.0

3.6

0.0

estimate

0.00

(3019225) pH of Specimen

1.04

0.07

1.5

4.7

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

111

0.89

0.06

1.2

1.7

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

168

1.09

0.06

2.4

2.9

0.8

0.7

ug/l

—

116

(3015736) pH of Urine

302

0.94

0.05

2.3

3.5

—

(3013512) EKG study

251

0.94

0.04

4.1

4.0

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

260

0.95

0.04

2.4

2.5

75.5

56.2

u/l

0.52

236

(3031040) Bacteria [#/volume] in Urine by Automated count

510

1.04

0.03

4.7

4.2

—

362.9

—

(3012516) Albumin [Mass/volume] in Urine

239

0.95

0.03

2.7

3.3

22.6

59.3

mg/l

1.22

142

(3020682) Albumin/Creatinine [Ratio] in Urine

256

0.97

0.00

3.5

4.2

3.2

7.9

mg/mmol

1.03

145

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

107

1.03

0.00

1.4

—

(3021601) Nitrite [Presence] in Urine by Test strip

387

1.01

0.00

4.1

4.8

0.0

estimate

0.00

(3007164) IgA [Mass/volume] in Serum or Plasma

154

0.97

0.00

1.1

1.7

2.5

3.1

g/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

229

1.01

0.00

3.5

3.0

—

(3037522) Nuclear Ab [Titer] in Serum

1.01

0.00

1.1

1.4

—

619.1

—

(40765096) Chromosome analysis panel by Banding

0.00

0.0

1.0

—

(3047189) Immunofixation for 24 hour Urine

0.00

0.0

1.6

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

2.4

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

12.5

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

2.0

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.0

1.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

1.3

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

29.6

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(36660697) Celiac disease serology panel - Serum

0.85

0.00

1.0

1.1

—

(3010375) cycloSPORINE [Mass/volume] in Blood

0.00

0.0

45.0

—

107.0

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(3037556) Urate [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

(4027681)

0.00

0.0

1.2

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.0

1.3

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.2

—

250.5

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

4.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.2

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.0

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.8

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.0

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(4146454)

0.00

0.0

3.3

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.01

0.00

1.1

1.8

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.0

2.5

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.0

1.6

—

63.4

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

21.7

—

1123.3

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.0

1.3

—

(3020779) Urea [Moles/volume] in Serum or Plasma

0.93

0.00

2.9

6.9

9.0

9.7

mmol/l

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(4268621)

0.00

0.0

1.5

—

(4024509)

0.00

0.0

1.0

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.5

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3020491) Glucose [Moles/volume] in Blood

0.00

0.0

2.3

—

6.6

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

0.0

2.5

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

17.3

—

693.0

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.0

1.2

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.5

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

0.0

15.1

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.2

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

170

1.00

0.00

1.9

4.0

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.3

—

(3010726) Horse dander IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.9

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.7

—

(3004451) EKG impression Narrative

0.00

0.0

1.5

—

(1175426) CD3 cells/100 lymphocytes in Blood

0.00

0.0

2.7

—

76.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.00

0.00

1.0

1.4

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.96

0.00

2.0

1.7

—

(3017569) Oxygen content in Arterial blood

0.00

0.0

12.0

—

(3020191) Ethanol [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

1.4

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_CILIARY and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_CILIARY.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_CILIARY – Benign neoplasm: Ciliary body

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Ciliary body

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints