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Tuberculosis of other organs, strict

EFO Endpoint Browser PheWeb

AB1_TUBERCU_OTH_ORG

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — A18
  • Hospital discharge: ICD-9 — 0[1]
  • Hospital discharge: ICD-8 — 0[1]
  • Hospital discharge: excluded ICD-9 — 01[1-3]|018
  • Hospital discharge: excluded ICD-8 — 01[1-3]|018
  • Cause of death: ICD-10 — A18
  • Cause of death: ICD-9 — 0[1]
  • Cause of death: ICD-8 — 0[1]
  • Cause of death: excluded ICD-9 — 01[1-3]|018
  • Cause of death: excluded ICD-8 — 01[1-3]|018

2 out of 7 registries used, show all original rules.

927

4. Check minimum number of events

None

927

5. Include endpoints

None

927

6. Filter based on genotype QC (FinnGen only)

927

Control definitions (FinnGen only)

Control exclude
AB1_TUBERCULOSIS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF12

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 14840 7877 6491
Only index persons 8037 4922 3115
Unadjusted period prevalence (%)
Whole population 0.21 0.23 0.18
Only index persons 0.16 0.18 0.12
Median age at first event (years)
Whole population 54.25 54.45 54.01
Only index persons 46.80 48.59 43.96

-FinnGen-

Key figures

All Female Male
Number of individuals 927 469 458
Unadjusted period prevalence (%) 0.18 0.16 0.20
Median age at first event (years) 47.80 44.67 51.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
841
Matched controls
8421
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
01710
ICD-8 Finland
Tuberculosis of other organs, Lymphonodorum colli
+∞
109.8
103
*
A18.2
ICD-10 Finland
Tuberculous peripheral lymphadenopathy
+∞
106.6
100
*
01908
ICD-8 Finland
Late effects of tuberculosis, Sequelae aliae o tuberculosis organorum respirationis
+∞
45.2
43
*
A18.0
ICD-10 Finland
Tuberculosis of bones and joints
+∞
44.1
42
*
01600
ICD-8 Finland
Tuberculosis of genito-urinary system, Renis
+∞
42.0
40
*
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
39.9
39.2
49
13
A18.4
ICD-10 Finland
Tuberculosis of skin and subcutaneous tissue
+∞
37.8
36
*
0172A
ICD-9 Finland
Tuberculosis of other organs, Peripheral lymph nodes
+∞
37.8
36
*
A18.1
ICD-10 Finland
Tuberculosis of genitourinary system
+∞
34.6
33
*
A18.8
ICD-10 Finland
Tuberculosis of other specified organs
+∞
34.6
33
*
M49.0*A18.0
ICD-10 Finland
Tuberculosis of spine
+∞
31.4
30
*
01102
ICD-8 Finland
Pulmonary tuberculosis, Non cavernosa
+∞
30.4
29
*
A70
ICPC
Tuberculosis
290.7
27.9
28
*
01718
ICD-8 Finland
Tuberculosis of other organs, Lymphonodorum periphericorum aliorum
+∞
23.0
22
*
Y3429
ICD-8 Finland
Follow-up examination of illness, accident or surgery, Other inactive tuberculosis cases
215.1
20.7
21
*
01500
ICD-8 Finland
Tuberculosis of bones and joints, Of vertebral column
+∞
17.8
17
*
A18.3
ICD-10 Finland
Tuberculosis of intestines, peritoneum and mesenteric glands
+∞
17.8
17
*
01904
ICD-8 Finland
Late effects of tuberculosis, Adhaesiones pleurae
+∞
16.7
16
*
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
+∞
15.7
15
*
N33.0*A18.1
ICD-10 Finland
Tuberculous cystitis
+∞
15.7
15
*
Y3409
ICD-8 Finland
Follow-up examination of illness, accident or surgery, Treated inactive pulmonary tuberculosis
20.5
15.2
22
11
01909
ICD-8 Finland
Late effects of tuberculosis, Sequelae NUD o tuberculosis organorum respirationis
+∞
14.6
14
*
01797
ICD-8 Finland
Tuberculosis of other organs, Suspecta
+∞
14.6
14
*
1370X
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,MUU JÄLKITILA]
54.3
13.8
16
*
01597
ICD-8 Finland
Tuberculosis of bones and joints, Suspecta
+∞
13.6
13
*
M01.1*A18.0
ICD-10 Finland
Tuberculous arthritis
+∞
13.6
13
*
B90.2
ICD-10 Finland
Sequelae of tuberculosis of bones and joints
142.2
13.5
14
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
8.7
12.8
27
32
0151X
ICD-9 Finland
Tuberculosis of bones and joints, Hip[TUBERCULOSIS COXAE,EPÄILTY]
+∞
11.5
11
*
01510
ICD-8 Finland
Tuberculosis of bones and joints, Of hip
+∞
11.5
11
*
01588
ICD-8 Finland
Tuberculosis of bones and joints, Of other specified bones and joints
+∞
11.5
11
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.2
11.4
116
559
A15.1
ICD-10 Finland
Tuberculosis of lung, confirmed by culture only
+∞
10.4
10
*
01220
ICD-8 Finland
Other respiratory tuberculosis, Pleurisy with effusion without mention of cause
+∞
10.4
10
*
PJA10
NOMESCO Finland
Exploration of lymph nodes
7.2
10.3
24
34
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
4.3
10.1
36
86
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.0
10.0
133
718
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
3.6
9.6
42
121
H02AB07
ATC
prednisone; oral
2.0
9.5
139
774
01719
ICD-8 Finland
Tuberculosis of other organs, Lymphonodorum NUD
+∞
9.4
9
*
0150X
ICD-9 Finland
Tuberculosis of bones and joints, Vertebral column[SELKÄRANKATUBERKULOOSI,EPÄILTY]
+∞
9.4
9
*
H03.1*A18.4
ICD-10 Finland
Lupus vulgaris: of eyelid
+∞
9.4
9
*
01608
ICD-8 Finland
Tuberculosis of genito-urinary system, Suspecta
+∞
9.4
9
*
L04AX01
ATC
azathioprine; systemic
3.4
9.0
42
127
J01MA12
ATC
levofloxacin; systemic
1.8
8.8
170
1040
H32.0*A18.5
ICD-10 Finland
Lupus chorioretinitis
+∞
8.3
8
*
01701
ICD-8 Finland
Tuberculosis of other organs, Erythema induratum tuberculosum
+∞
8.3
8
*
01901
ICD-8 Finland
Late effects of tuberculosis, Emphysema
+∞
8.3
8
*
01903
ICD-8 Finland
Late effects of tuberculosis, Fibrosis pulmonum
+∞
8.3
8
*
01604
ICD-8 Finland
Tuberculosis of genito-urinary system, Prostatae, vesiculae seminalis sive testis
+∞
8.3
8
*
01930
ICD-8 Finland
Late effects of tuberculosis, Columnae vertebralis
+∞
8.3
8
*
01900
ICD-8 Finland
Late effects of tuberculosis, Bronchiectasia
+∞
8.3
8
*
01931
ICD-8 Finland
Late effects of tuberculosis, Coxae
+∞
8.3
8
*
H02AB06
ATC
prednisolone; systemic
1.5
8.1
374
2886
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.9
8.0
47
169
M79.3
ICD-10 Finland
Panniculitis, unspecified
18.5
7.6
11
6
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.0
7.4
95
502
A19.1
ICD-10 Finland
Acute miliary tuberculosis of multiple sites
+∞
7.3
7
*
01107
ICD-8 Finland
Pulmonary tuberculosis, Suspecta
+∞
7.3
7
*
K93.0*A18.3
ICD-10 Finland
Tuberculous disease of the intestines, peritoneum and mesentery glands
+∞
7.3
7
*
R06.0
ICD-10 Finland
Dyspnoea
1.6
7.1
216
1497
R03DA04
ATC
theophylline; systemic, rectal
2.1
7.0
75
368
R03AC12
ATC
salmeterol; inhalant
2.4
6.9
57
247
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.6
6.8
202
1393
C03CA01
ATC
furosemide; systemic
1.5
6.7
339
2638
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.4
6.6
30
91
R03AC02
ATC
salbutamol; inhalant
1.5
6.6
370
2939
R50.9
ICD-10 Finland
Fever, unspecified
1.8
6.5
111
653
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
8.2
6.3
13
16
H02AB04
ATC
methylprednisolone; systemic
1.8
6.3
118
712
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
6.3
245
1798
A15.4
ICD-10 Finland
Tuberculosis of intrathoracic lymph nodes, confirmed bacteriologically and histologically
+∞
6.3
6
*
0140X
ICD-9 Finland
Tuberculosis of intestines, peritoneum and mesenteric glands, Tuberculous peritonitis[PERITONITIS TUBERCULOSA,EPÄILTY]
+∞
6.3
6
*
01731
ICD-8 Finland
Tuberculosis of other organs, Otitis media tuberculosa
+∞
6.3
6
*
I41.0*A18.8
ICD-10 Finland
Tuberculosis of myocardium
+∞
6.3
6
*
A18.5
ICD-10 Finland
Tuberculosis of eye
+∞
6.3
6
*
01401
ICD-8 Finland
Tuberculosis of intestines, peritoneum and mesenteric glands, Peritonei et lymphonodorum mesenterii
+∞
6.3
6
*
1373X
ICD-9 Finland
Late effects of tuberculosis of bones and joints
+∞
6.3
6
*
01210
ICD-8 Finland
Other respiratory tuberculosis, Tuberculosis pleurae, pleuritis exsudativa tuberculosa
+∞
6.3
6
*
0178X
ICD-9 Finland
Tuberculosis of other organs, Oesophagus[TUBERCULOSIS ALIORUM ORGANORUM]
+∞
6.3
6
*
01101
ICD-8 Finland
Pulmonary tuberculosis, Cavernosa
+∞
6.3
6
*
N29.1*A18.1
ICD-10 Finland
Tuberculosis of the kidney or ureter
+∞
6.3
6
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
6.2
114
683
Z03.0
ICD-10 Finland
Observation for suspected tuberculosis
12.6
6.1
10
8
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.5
6.1
46
191
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
6.0
350
2785

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
43
108
4.13
15.64
3.9
2.6
—
—
—
0
0
51
182
2.91
10.86
1.2
1.3
0.3
2.0
u/ml
—
6
14
93
456
2.16
10.10
2.8
2.8
10.7
10.6
g/l
0.08
83
411
21
42
5.09
10.08
1.1
1.2
—
—
—
0
0
46
163
2.92
9.93
1.7
2.0
11.5
13.4
mg/l
0.79
39
147
21
44
4.86
9.57
2.3
2.4
—
—
—
0
0
125
699
1.91
9.44
1.6
1.6
—
—
—
0
0
130
738
1.89
9.37
1.4
1.3
487.1
464.0
titre
0.07
34
165
298
2210
1.51
7.57
9.7
5.1
—
—
—
0
0
72
359
2.09
7.50
1.7
1.7
1.0
1.5
g/l
1.29
60
321
14
27
5.25
6.98
1.6
1.7
941.5
859.2
u/ml
0.08
14
27
125
769
1.72
6.85
1.8
1.4
—
—
—
0
0
25
79
3.22
6.60
1.7
1.6
0.8
0.8
g/l
0.02
17
65
142
915
1.65
6.54
6.1
7.3
1.2
1.4
mmol/l
0.19
116
696
142
919
1.64
6.43
6.0
7.3
5.2
5.1
kpa
0.62
135
869
95
550
1.81
6.41
3.9
5.0
—
—
—
0
0
142
920
1.64
6.40
6.0
7.2
11.1
11.6
kpa
0.75
134
870
129
816
1.67
6.38
6.1
7.6
94.8
95.4
%
0.38
124
784
9
5
18.15
6.27
1.2
1.0
—
—
—
0
0
156
1055
1.58
5.88
2.8
2.0
—
—
—
0
0
291
2238
1.44
5.87
5.0
4.2
—
—
—
0
0
411
3361
1.40
5.85
9.0
5.3
0.2
0.2
e9/l
0.89
362
2912
84
482
1.82
5.85
4.2
3.9
7.4
7.4
ph
0.16
11
52
65
345
1.95
5.74
1.8
1.9
8.0
2.3
ug/l
0.45
56
291
8
5
16.13
5.41
1.0
1.0
—
—
—
0
0
396
3249
1.38
5.40
8.8
5.1
0.0
0.0
e9/l
1.15
346
2776
440
3673
1.38
5.39
7.6
5.8
10.9
11.9
umol/l
1.13
414
3455
393
3232
1.38
5.23
8.7
5.1
0.6
0.6
e9/l
0.50
340
2755
400
3310
1.37
5.08
9.0
5.2
1.7
1.9
e9/l
2.53
356
2881
32
135
2.42
5.02
1.1
1.2
2.2
2.9
u/ml
—
6
19
22
77
2.90
4.95
1.5
1.4
116.2
118.2
u/ml
—
6
16
55
292
1.94
4.89
4.0
4.3
25.0
25.1
mmol/l
0.07
49
271
125
839
1.57
4.85
2.3
1.7
—
—
—
0
0
68
390
1.80
4.77
7.7
10.6
—
—
—
0
0
233
1781
1.41
4.72
3.5
2.8
1577.4
9475.9
umol/l
4.42
202
1486
439
3714
1.35
4.72
8.3
6.6
1.2
1.2
mmol/l
0.15
379
3086
30
127
2.41
4.69
2.2
1.5
—
—
—
0
0
27
109
2.52
4.66
1.7
1.5
—
—
—
0
0
18
58
3.15
4.65
1.2
1.2
—
—
—
0
0
276
2182
1.38
4.56
2.7
2.4
64.7
56.8
u/l
0.69
255
1994
63
360
1.80
4.49
3.6
3.9
—
—
—
0
0
157
1128
1.47
4.42
4.1
3.0
0.8
0.8
mmol/l
0.29
151
1034
28
119
2.40
4.36
1.5
1.2
—
—
—
0
0
137
962
1.50
4.32
1.3
1.2
25.9
38.8
iu/ml
1.12
44
309
401
3406
1.31
3.97
7.7
5.9
1.2
1.2
mmol/l
0.00
379
3018
35
171
2.09
3.95
2.9
1.7
13668.5
17061.3
e6/l
0.21
23
120
364
3060
1.31
3.86
9.7
5.2
60.1
58.5
%
1.54
337
2838
369
3110
1.31
3.83
10.2
5.5
25.1
26.2
%
1.00
341
2861
101
683
1.54
3.80
6.0
6.6
1.3
1.4
mmol/l
0.99
96
651
20
78
2.60
3.73
1.6
1.2
271.9
303.0
u/ml
0.16
11
42
55
321
1.76
3.69
3.4
2.9
—
—
—
0
0
252
2025
1.34
3.63
2.7
2.2
3.0
3.2
mg/l
0.46
217
1690
361
3052
1.30
3.61
10.4
5.5
8.7
8.8
%
0.39
333
2828
440
3820
1.29
3.58
12.0
8.3
4.6
4.3
e9/l
1.08
385
3326
352
2970
1.30
3.56
10.2
5.3
0.7
0.6
%
0.05
328
2743
87
578
1.56
3.55
2.0
1.8
379.8
382.3
nmol/l
0.02
78
512
161
1209
1.40
3.55
3.0
2.3
11.2
12.0
umol/l
0.70
146
1105
65
404
1.65
3.49
7.6
9.2
24.4
24.6
mmol/l
0.16
60
370
21
87
2.45
3.49
1.7
1.4
—
—
—
0
0
14
47
3.01
3.42
2.1
1.3
8.6
8.0
g/l
—
9
35
14
47
3.01
3.42
2.1
1.3
2.6
2.8
g/l
—
9
35
14
47
3.01
3.42
2.1
1.3
0.6
0.5
g/l
—
9
35
358
3040
1.29
3.42
10.0
5.3
2.8
2.9
%
0.24
331
2801
46
262
1.80
3.37
3.4
2.9
0.4
0.3
g/l
0.59
17
90
14
49
2.89
3.20
2.1
1.3
—
—
—
0
0
78
521
1.54
3.13
4.8
4.1
0.3
0.1
%
0.78
32
160
311
2618
1.28
3.12
3.6
3.2
1779.9
2005.5
ng/l
0.39
269
2252
93
649
1.48
3.05
8.4
7.7
—
—
—
0
0
7
12
5.87
3.02
1.3
1.7
93.7
88.4
ng/l
—
7
12
16
63
2.57
2.97
1.1
1.2
—
—
—
0
0
546
4943
1.25
2.88
6.7
4.1
17.5
14.8
mm/h
2.73
504
4468
139
1055
1.37
2.88
3.2
2.4
21.5
21.1
%
0.09
112
896
269
2243
1.28
2.88
5.3
3.8
7.4
7.4
ph
0.13
54
414
6
9
6.70
2.87
1.3
1.2
—
—
—
0
0
11
36
3.08
2.81
1.1
1.2
—
—
—
0
0
80
552
1.49
2.79
4.9
4.0
1.3
0.8
%
0.50
33
174
25
125
2.03
2.73
1.2
1.2
3.8
3.8
mmol/l
0.02
25
116
54
343
1.61
2.71
1.4
1.3
—
—
—
0
0
6
10
6.03
2.70
1.3
1.5
—
—
—
0
0
6
10
6.03
2.70
1.0
1.0
—
—
—
0
0
84
592
1.46
2.64
1.6
1.4
—
—
—
0
0
72
492
1.50
2.64
5.1
3.9
0.9
0.5
%
0.59
22
127
144
1119
1.34
2.57
3.0
2.3
2.3
2.3
g/l
0.20
128
1017
143
1114
1.34
2.51
1.6
1.5
2.8
2.6
g/l
0.27
89
620
127
972
1.36
2.50
2.6
2.3
1.8
1.8
%
0.03
107
850
126
965
1.35
2.47
6.7
6.3
103.8
104.1
mmol/l
0.24
126
938
373
3276
1.23
2.47
5.5
4.4
33.8
34.6
g/l
1.48
345
3002
573
6174
0.81
2.44
4.9
4.5
4.4
4.5
mmol/l
0.78
517
5527
16
70
2.31
2.42
1.2
1.3
—
—
—
0
0
49
314
1.59
2.40
5.7
4.5
—
—
—
0
0
16
71
2.28
2.35
1.3
1.2
1.4
7.1
u/ml
—
8
28
92
676
1.40
2.33
2.2
2.8
66.5
65.9
g/l
0.30
77
604
264
2249
1.24
2.29
2.3
2.1
166.4
257.9
u/l
1.24
239
2097
568
6109
0.82
2.28
4.7
4.5
1.4
1.5
mmol/l
0.34
507
5423
12
47
2.57
2.27
2.5
2.1
—
—
—
0
0
32
186
1.75
2.27
1.9
4.0
—
—
—
0
0
96
715
1.38
2.25
2.3
2.4
70.1
68.1
e9/l
0.20
70
566
18
86
2.11
2.24
2.2
2.2
—
—
—
0
0
357
3148
1.22
2.22
10.2
11.1
1.3
1.3
inr
0.16
88
841
84
615
1.40
2.19
5.3
3.5
110.4
91.1
ng/l
0.86
76
521
22
115
1.94
2.17
4.0
2.9
4.4
4.5
e9/l
0.11
22
115
117
905
1.34
2.17
1.3
1.2
—
—
—
0
0
38
236
1.64
2.14
4.9
7.5
1.3
1.4
mmol/l
0.27
32
207
86
635
1.39
2.14
2.4
2.0
107.1
157.9
ug/g
1.50
62
492
18
88
2.07
2.12
1.1
1.1
—
—
—
0
0
20
102
1.98
2.11
1.3
1.3
—
—
—
0
0
8
25
3.22
2.10
1.3
1.1
460.9
187.4
iu/ml
—
8
25
8
25
3.22
2.10
1.0
1.4
—
—
—
0
0
16
75
2.15
2.09
1.8
1.2
—
—
—
0
0
524
5658
0.83
2.09
25.6
18.6
37.5
38.4
%
0.81
296
3515
5
10
5.02
2.07
1.6
1.5
—
—
—
0
0
118
921
1.32
2.06
1.4
1.2
21.7
13.2
u/ml
0.32
40
311
91
683
1.37
2.05
2.9
2.1
0.2
0.2
g/l
0.79
83
629
597
6364
0.83
2.05
5.3
5.2
2.5
2.6
mmol/l
0.64
534
5673
73
528
1.42
2.05
1.6
1.4
—
—
—
0
0
97
736
1.36
2.05
5.1
4.3
—
—
—
0
0
100
765
1.34
2.00
4.6
3.3
1.8
2.1
mmol/l
0.29
82
598
68
488
1.42
2.00
5.0
4.1
0.0
0.7
%
0.55
24
137
197
1650
1.25
1.98
8.2
6.3
—
—
—
0
0
65
464
1.43
1.97
1.5
1.4
—
—
—
0
0
7
21
3.35
1.96
2.3
2.1
—
—
—
0
0
86
646
1.37
1.94
4.5
3.7
—
—
—
0
0
27
157
1.74
1.94
4.7
4.0
—
—
—
0
0
517
4766
1.19
1.90
6.4
4.8
—
—
—
0
0
22
121
1.84
1.89
5.3
3.2
59.4
60.5
%
0.15
22
121
97
746
1.34
1.89
2.6
2.6
5.9
5.6
ug/l
0.09
80
623
7
22
3.20
1.88
1.1
1.0
—
—
—
0
0
77
572
1.38
1.87
2.3
2.5
—
—
—
0
0
10
40
2.52
1.84
1.1
1.1
—
105.7
—
0
7
57
403
1.44
1.83
4.1
3.0
4.3
4.0
e9/l
0.36
41
281
86
653
1.35
1.83
3.3
2.8
3.9
4.4
kpa
1.52
81
628
33
207
1.62
1.82
4.1
3.2
24.1
25.0
mmol/l
0.51
33
173
7
23
3.06
1.80
1.1
1.1
—
—
—
0
0
140
1143
1.26
1.76
2.4
1.9
30.3
29.7
s
0.44
134
1101
516
4776
1.18
1.75
7.0
5.3
90.3
3270.2
e6/l
2.22
14
90
15
74
2.04
1.75
2.9
3.1
64.2
55.2
%
—
9
52
12
54
2.24
1.74
1.0
1.1
—
—
—
0
0
195
1654
1.23
1.74
3.6
2.6
5.5
5.6
e6/l
0.02
171
1450
33
210
1.59
1.73
2.8
1.9
21.3
21.7
s
0.28
26
189
29
179
1.64
1.71
1.4
1.6
—
—
—
0
0
17
89
1.93
1.70
1.4
1.3
—
—
—
0
0
16
82
1.97
1.70
1.9
1.2
0.7
0.6
nmol/l
0.13
16
75
189
1602
1.23
1.70
4.8
4.2
—
—
—
0
0
294
2602
1.19
1.68
4.4
3.7
—
—
—
0
0
38
252
1.53
1.68
1.5
1.4
—
—
—
0
0
30
188
1.62
1.68
4.6
2.9
7.8
7.8
kpa
0.02
30
169
21
119
1.78
1.67
1.5
1.3
—
—
—
0
0
14
265
0.52
1.66
1.4
1.4
—
—
—
0
0
369
3337
1.18
1.63
4.9
4.2
0.0
0.0
estimate
0.00
77
623
27
167
1.64
1.59
3.9
2.0
120.5
125.0
g/l
0.36
20
120
14
70
2.02
1.59
2.4
1.6
—
—
—
0
0
32
207
1.57
1.58
1.4
1.5
—
—
—
0
0
456
4201
1.17
1.58
5.9
4.9
6.6
6.8
mmol/l
2.02
437
3933
25
152
1.66
1.58
4.3
2.2
14.6
15.4
%
0.31
14
70
54
392
1.40
1.54
1.7
1.6
1.5
1.6
g/l
0.30
49
348
18
100
1.82
1.54
1.2
1.2
—
—
—
0
0
5
15
3.35
1.52
1.0
1.0
1111.0
1314.5
miu/ml
—
5
15
16
86
1.88
1.51
4.1
4.3
—
—
—
0
0
220
1917
1.19
1.49
1.7
1.6
18.4
20.8
nmol/l
1.48
193
1594
24
147
1.65
1.48
4.1
2.8
—
—
—
0
0
49
353
1.41
1.46
1.4
1.3
—
—
—
0
0
38
261
1.48
1.45
2.1
3.7
44.2
81.3
mg/l
0.86
27
216
557
5899
0.86
1.45
4.3
4.1
1.3
1.3
mmol/l
0.28
492
5177
17
95
1.80
1.43
1.8
1.7
87.6
89.6
%
0.43
17
95
170
1451
1.21
1.43
1.9
1.6
2.3
1.3
mg/l
0.91
136
1134
38
262
1.47
1.43
2.1
3.7
27.8
51.5
mg/l
1.06
27
218
212
1850
1.19
1.41
5.3
4.6
0.0
0.0
estimate
0.69
70
592
346
3144
1.16
1.39
4.7
4.2
—
—
—
0
0
196
1704
1.19
1.36
1.8
1.8
436.0
12252824.9
pmol/l
1.08
164
1363
43
309
1.41
1.32
1.6
1.2
—
—
—
0
0
6
24
2.51
1.30
1.7
2.5
—
—
—
0
0
558
5266
1.15
1.29
11.2
7.2
82.7
80.5
u/l
0.43
533
4873
368
3375
1.15
1.29
5.1
4.3
0.0
0.0
estimate
0.00
77
606
5
18
2.79
1.28
1.6
1.3
—
—
—
0
0
229
2029
1.17
1.27
4.4
3.3
—
—
—
0
0
331
3019
1.15
1.24
4.9
4.2
37.1
55.4
ng/l
0.90
263
2300
5
19
2.64
1.21
1.2
1.2
—
—
—
0
0
362
3331
1.14
1.19
6.7
5.7
0.0
0.0
estimate
0.00
76
620
21
133
1.59
1.18
1.7
1.5
—
—
—
0
0
11
198
0.55
1.17
1.4
1.5
—
—
—
0
0
19
118
1.62
1.15
3.9
3.6
1.3
1.3
%
0.03
13
96
152
1312
1.19
1.15
6.2
4.5
—
—
—
0
0
8
39
2.06
1.15
9.9
1.5
—
—
—
0
0
14
80
1.76
1.13
1.6
1.2
—
—
—
0
0
490
5188
0.88
1.13
31.7
22.6
330.2
331.0
g/l
0.97
484
5122
155
1778
0.85
1.12
3.5
3.2
—
—
—
0
0
141
1630
0.84
1.12
1.7
1.6
1.4
1.3
mmol/l
0.83
122
1348
15
88
1.72
1.11
1.7
1.6
—
—
—
0
0
50
382
1.33
1.10
1.3
1.2
—
—
—
0
0
5
21
2.39
1.09
1.4
2.1
—
—
—
0
0
640
6655
0.88
1.08
22.8
16.2
—
—
—
0
0
683
7069
0.87
1.06
35.2
24.7
7.3
6.9
e9/l
0.70
661
6808
683
7068
0.87
1.06
35.3
24.9
129.6
131.6
g/l
2.91
675
6905
289
2638
1.14
1.06
5.6
4.0
249.4
141.6
e6/l
0.28
214
1931
683
7067
0.87
1.05
35.2
24.7
4.3
4.4
e12/l
0.92
662
6809
683
7067
0.87
1.05
35.0
24.6
30.3
30.4
pg
0.72
672
6904
15
90
1.68
1.04
1.0
1.0
—
—
—
0
0
683
7065
0.87
1.04
35.0
24.6
91.6
91.6
fl
0.09
672
6904
94
784
1.22
1.03
2.8
2.7
7.2
9.0
umol/l
0.94
83
680
683
7064
0.87
1.03
35.2
24.7
244.0
241.9
e9/l
0.32
666
6824
26
180
1.46
1.01
3.1
4.1
52.4
28.6
mg/l
1.30
20
120
69
558
1.26
1.00
1.5
1.4
—
—
—
0
0
65
523
1.26
0.99
1.7
1.5
—
—
—
0
0
5
23
2.18
0.98
1.2
1.1
—
—
—
0
0
9
51
1.77
0.94
1.2
1.4
—
—
—
0
0
188
1681
1.15
0.93
3.2
2.4
—
—
—
0
0
10
55
1.83
0.92
1.3
1.2
30.4
34.2
mmol/l
—
10
49
25
176
1.43
0.91
3.5
4.4
3.3
2.9
mmol/l
0.19
19
117
253
2313
1.13
0.90
4.8
3.5
87.3
101.5
e6/l
0.11
201
1804
9
153
0.58
0.89
1.1
1.3
—
—
—
0
0
8
42
1.91
0.88
1.3
1.0
—
—
—
0
0
193
1738
1.14
0.87
1.9
1.8
1159.3
1200.9
nmol/l
0.29
150
1272
39
300
1.31
0.85
1.3
1.4
—
—
—
0
0
75
626
1.22
0.85
3.9
3.8
1.2
1.2
mmol/l
0.12
69
536
14
88
1.60
0.84
2.1
2.5
—
—
—
0
0
302
2803
1.11
0.82
3.6
2.7
159.2
138.7
ug/l
0.76
274
2515
24
172
1.41
0.81
2.9
2.6
—
—
—
0
0
47
375
1.27
0.80
5.6
3.4
24.0
24.1
mmol/l
0.05
42
337
608
6295
0.90
0.80
5.0
4.9
6.0
6.1
mmol/l
0.94
539
5561
11
66
1.67
0.79
1.3
1.3
—
—
—
0
0
81
689
1.19
0.77
1.3
1.3
—
—
—
0
0
0
28
0.00
0.76
0.0
1.5
—
43.5
—
0
7
15
99
1.52
0.76
1.5
1.4
—
—
—
0
0
14
91
1.55
0.75
1.8
1.2
157551.1
104480.3
e6/l
—
9
51
22
158
1.40
0.75
1.1
1.1
—
—
—
0
0
175
1585
1.13
0.73
3.9
2.9
523.5
546.3
mosm/kgh2o
0.89
152
1338
661
6801
0.90
0.72
15.3
10.7
24.1
24.2
u/l
0.07
642
6482
13
84
1.56
0.72
1.1
1.2
—
—
—
0
0
500
5212
0.91
0.72
27.8
20.5
14.2
13.9
%
2.08
493
5072
12
76
1.59
0.72
1.9
1.2
—
—
nmol/l
—
0
0
9
143
0.63
0.70
1.8
1.8
—
—
—
0
0
21
152
1.39
0.69
1.4
1.1
—
65.8
—
0
12
583
6025
0.91
0.67
6.7
6.4
40.8
41.0
mmol/mol
0.20
539
5441
5
28
1.79
0.66
1.4
1.1
—
—
—
0
0
5
28
1.79
0.66
4.2
3.8
—
—
—
0
0
273
2556
1.10
0.62
2.4
2.3
—
—
—
0
0
6
102
0.59
0.62
1.3
1.6
34.8
43.7
nmol/l
—
6
96
306
2881
1.09
0.62
14.8
9.7
0.0
0.0
e9/l
0.81
251
2340
10
63
1.59
0.62
2.2
1.3
718.4
122166.6
e6/l
—
5
45
8
51
1.57
0.60
1.5
1.7
9.6
10.8
%
—
8
51
12
174
0.69
0.59
3.7
2.4
—
—
—
0
0
37
301
1.24
0.57
4.8
3.7
1.4
1.4
mmol/l
0.00
37
295
8
54
1.49
0.57
1.0
1.1
—
—
—
0
0
10
65
1.54
0.55
4.5
3.7
14.3
34.6
mg/l
—
10
54
454
4716
0.93
0.54
5.1
4.3
—
—
—
0
0
226
2115
1.09
0.52
4.6
3.3
0.2
0.6
e6/l
4.51
182
1627
31
251
1.24
0.51
5.6
3.7
3.8
4.0
mmol/l
0.72
31
227
48
408
1.19
0.50
2.4
2.5
—
—
—
0
0
576
5919
0.93
0.50
5.3
4.8
2.0
2.0
mu/l
0.35
519
5243
14
101
1.39
0.49
1.4
1.4
27.3
30.5
iu/l
—
9
82
274
2593
1.08
0.49
3.0
3.2
2.3
2.4
mmol/l
1.07
234
2187
7
45
1.56
0.49
2.0
3.0
—
—
—
0
0
7
45
1.56
0.49
1.6
1.1
—
—
—
0
0
36
431
0.83
0.49
4.6
4.2
—
—
—
0
0
7
46
1.53
0.48
1.3
14.4
—
—
—
0
0
163
1510
1.10
0.48
6.2
4.8
1.0
1.0
kg/l
0.69
26
225
7
48
1.46
0.47
1.0
1.8
—
—
—
0
0
92
829
1.12
0.46
3.2
3.8
49.8
28.1
ug/l
0.22
73
688
24
297
0.80
0.45
2.8
3.1
375.2
10345.7
u/ml
0.58
19
250
10
69
1.45
0.44
1.1
1.1
—
—
—
0
0
18
230
0.78
0.44
1.4
1.2
—
—
—
0
0
20
157
1.28
0.43
1.1
1.1
—
—
—
0
0
5
31
1.62
0.43
4.2
6.3
—
—
—
0
0
6
94
0.64
0.42
1.3
1.1
—
—
—
0
0
5
32
1.57
0.42
4.2
3.7
—
—
—
0
0
50
572
0.87
0.42
1.5
1.6
—
—
—
0
0
33
277
1.20
0.41
2.7
2.1
—
—
—
0
0
8
58
1.38
0.41
1.3
1.3
—
—
—
0
0
5
33
1.52
0.41
1.8
1.8
—
—
—
0
0
32
268
1.20
0.41
2.0
2.5
35.9
36.7
g/l
0.33
22
225
8
59
1.36
0.41
1.1
1.2
—
—
—
0
0
11
79
1.40
0.41
1.0
1.1
—
—
—
0
0
235
2230
1.07
0.40
3.2
2.5
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
153.8
134.5
nmol/l
—
5
35
0
19
0.00
0.39
0.0
1.7
—
—
—
0
0
163
1527
1.08
0.39
4.7
4.2
632.6
194.3
ng/l
0.58
141
1302
220
2085
1.07
0.38
3.3
3.2
748.1
253.4
mg/l
0.56
138
1306
126
1170
1.09
0.37
29.1
29.4
1.4
1.4
inr
0.13
13
136
25
209
1.20
0.34
1.5
1.4
298.1
267.1
ug/g
0.29
16
118
11
83
1.33
0.32
1.8
1.4
—
—
—
0
0
11
83
1.33
0.32
1.8
1.4
—
—
—
0
0
11
83
1.33
0.32
1.8
1.4
—
—
—
0
0
11
83
1.33
0.32
1.8
1.4
—
—
—
0
0
21
251
0.83
0.31
4.2
5.1
—
—
—
0
0
222
2122
1.06
0.31
3.4
3.1
6.5
6.9
mmol/l
0.69
185
1734
29
250
1.17
0.29
3.5
3.3
0.8
0.8
nmol/l
0.17
24
200
16
130
1.23
0.29
1.7
1.9
49.3
59.1
%
0.79
16
130
134
1265
1.07
0.28
1.3
1.2
2.7
1.3
u/ml
0.53
37
300
231
2219
1.05
0.28
4.1
3.9
19.0
9.5
mg/mmol
0.95
146
1394
47
423
1.12
0.27
1.2
1.2
—
—
—
0
0
228
2196
1.05
0.25
4.8
4.3
—
—
—
0
0
11
87
1.27
0.24
1.1
1.3
—
—
—
0
0
11
87
1.27
0.24
1.1
1.3
—
—
—
0
0
11
87
1.27
0.24
6.1
4.4
370.0
351.9
umol/l
0.19
11
78
6
81
0.74
0.24
2.7
2.8
—
—
—
0
0
6
85
0.70
0.24
1.0
1.6
—
—
—
0
0
10
125
0.80
0.23
2.9
2.5
—
—
—
0
0
11
88
1.25
0.22
1.1
1.3
—
—
—
0
0
11
88
1.25
0.22
1.1
1.3
—
—
—
0
0
11
88
1.25
0.22
1.4
2.3
3.0
50.6
u/ml
0.53
11
82
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
18.1
—
0
11
0
11
0.00
0.21
0.0
1.3
—
55.7
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
11
89
1.24
0.21
1.0
1.3
161.6
230.3
miu/ml
—
5
40
117
1228
0.95
0.20
3.0
3.2
0.6
0.8
ug/l
2.43
79
850
6
51
1.18
0.19
1.2
1.1
—
—
—
0
0
11
90
1.22
0.19
1.0
1.1
—
—
—
0
0
6
53
1.13
0.18
1.0
1.2
—
—
—
0
0
6
53
1.13
0.18
1.5
1.2
—
—
—
0
0
676
6828
0.96
0.18
27.5
20.5
4.0
4.0
mmol/l
0.23
658
6605
52
483
1.08
0.18
3.6
3.6
—
—
—
0
0
11
132
0.83
0.18
1.6
2.5
—
—
—
0
0
16
185
0.86
0.18
2.3
2.4
40.6
74.0
ug/min
—
8
110
8
69
1.16
0.16
1.4
2.2
—
—
—
0
0
63
594
1.07
0.16
5.3
4.1
—
—
—
0
0
324
3177
1.03
0.15
2.3
2.2
90.1
93.9
pmol/l
0.75
176
1603
6
80
0.75
0.15
10.5
3.6
—
—
—
0
0
481
4874
0.97
0.15
4.3
3.9
15.4
15.1
pmol/l
2.18
435
4287
9
82
1.10
0.15
1.1
1.3
—
—
—
0
0
676
6814
0.97
0.14
27.4
20.4
139.2
139.6
mmol/l
1.96
660
6601
20
221
0.90
0.13
15.3
11.2
—
—
—
0
0
5
46
1.09
0.09
11.4
3.2
—
—
—
0
0
5
46
1.09
0.09
1.2
1.7
—
—
—
0
0
125
1219
1.03
0.09
4.4
3.2
4.2
2.5
e6/l
0.81
79
689
12
134
0.89
0.08
1.5
1.5
2.2
4.7
iu/l
—
5
42
152
1549
0.98
0.07
3.1
3.1
2.5
2.5
mmol/l
0.16
134
1345
17
184
0.92
0.07
1.4
1.2
—
—
—
0
0
151
1538
0.98
0.07
1.3
1.3
—
—
—
0
0
84
821
1.03
0.05
1.4
1.3
—
—
—
0
0
221
2191
1.01
0.04
4.8
5.4
3.4
5.4
ug/l
0.46
193
1908
34
330
1.03
0.03
1.1
1.2
36.8
137.0
iu/ml
—
8
118
17
178
0.95
0.02
1.1
1.1
—
—
—
0
0
13
137
0.95
0.01
1.1
1.2
—
—
—
0
0
655
6540
1.01
0.01
25.7
17.0
27.0
26.6
mg/l
0.10
576
5331
22
217
1.01
0.00
5.7
3.6
—
—
—
0
0
177
1771
1.00
0.00
4.9
4.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
6
60
1.00
0.00
3.2
2.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
0.00
1.4
1.1
—
—
—
0
0
5
50
1.00
0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
5.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
0.00
1.4
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
0.00
1.2
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_TUBERCU_OTH_ORG and mortality.

Females

Parameter HR [95% CI] p-value
AB1_TUBERCU_OTH_ORG 1.523 [1.36, 1.71] < 0.001
Birth year 0.997 [0.99, 1.01] 0.42

During the follow-up period (1.1.1998 — 31.12.2019), 693 out of 1730 females with AB1_TUBERCU_OTH_ORG died.

Males

Parameter HR [95% CI] p-value
AB1_TUBERCU_OTH_ORG 1.85 [1.57, 2.18] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 588 out of 1311 males with AB1_TUBERCU_OTH_ORG died.

Mortality risk

Mortality risk for people of age

years, who have AB1_TUBERCU_OTH_ORG.

N-year risk Females Males
1 0.092% 0.383%
5 0.859% 2.039%
10 2.049% 5.092%
15 4.14% 9.389%
20 7.541% 15.862%

Relationships between endpoints

↥

Index endpoint: AB1_TUBERCU_OTH_ORG – Tuberculosis of other organs, strict

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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