Frontotemporal dementia

FTD

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F020&G310
  • Cause of death: ICD-10 F020&G310

2 out of 7 registries used, show all original rules.

197

4. Check minimum number of events

None

197

5. Include endpoints

None

197

6. Filter based on genotype QC (FinnGen only)

194

Control definitions (FinnGen only)

Control exclude
F5_DEMENTIA, G6_ALZHEIMER, G6_AD_STRICT

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 194 88 106
Unadjusted period prevalence (%) 0.04 0.03 0.05
Median age at first event (years) 69.31 69.82 68.89

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
197
Matched controls
1970
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F02.09*G31.0
ICD-10 Finland
Dementia in Pick's disease without information on additional symptoms
+∞
202.8
158
*
G31.0
ICD-10 Finland
Circumscribed brain atrophy
+∞
116.6
100
*
N05AX08
ATC
risperidone; systemic
22.7
88.5
75
52
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
15.9
78.2
85
90
N05AH03
ATC
olanzapine; systemic
21.1
73.2
62
42
XA800
NOMESCO Finland
Neuropsychological investigation
29.6
71.8
51
23
TAB00
NOMESCO Finland
Lumbar puncture
21.2
69.5
58
38
N03AG01
ATC
valproic acid; systemic, rectal
19.2
63.0
55
39
F03
ICD-10 Finland
Unspecified dementia
179.5
62.0
62
5
Z2445
NOMESCO Finland
Psychologist
30.3
61.8
43
18
N05AH04
ATC
quetiapine; oral
10.2
56.9
88
145
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
10.8
50.0
66
88
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
14.3
49.8
51
47
P20
ICPC
Memory disturbance
8.6
45.3
76
134
P70
ICPC
Dementia
150.9
36.1
37
*
ZY010
NOMESCO Finland
Hospital outpatient
13.5
33.6
34
30
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
9.7
32.9
43
55
N05BA06
ATC
lorazepam; systemic, sublingual
10.0
30.2
38
46
F02.09
ICD-10 Finland
Dementia in Pick's disease without information on additional symptoms
+∞
28.9
27
*
N06DA02
ATC
donepezil; oral
63.2
28.1
32
6
A28
ICPC
Limited function/disability NOS
5.3
27.9
81
231
N06DX01
ATC
memantine; oral
73.0
27.9
31
5
N06DA03
ATC
rivastigmine; oral, transdermal
258.9
23.1
23
*
F06.7
ICD-10 Finland
Mild cognitive disorder
19.5
21.9
33
20
F0203, G310,
ICD-10 Finland
+∞
20.1
19
*
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
8.1
20.1
29
41
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
8.2
19.6
28
39
AA1AD
NOMESCO Finland
CT of head and brain
3.7
18.1
94
391
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
16.9
16
*
F0204, G310,
ICD-10 Finland
+∞
16.9
16
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
5.9
16.7
33
65
G30.1
ICD-10 Finland
Alzheimer disease with late onset
65.6
16.0
18
*
SPAT1245
SPAT
Provision of support and information to patient’s family members
8.0
16.0
23
32
F0200, G310,
ICD-10 Finland
+∞
15.8
15
*
N05BA04
ATC
oxazepam; oral
3.5
15.7
78
310
N06AX11
ATC
mirtazapine; oral
3.4
15.7
95
427
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
22.3
15.5
22
11
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
6.7
15.2
26
44
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
7.1
14.9
24
38
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
+∞
14.8
14
*
SPAT1234
SPAT
Support of social functional capacity
6.7
14.2
24
40
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
11.8
13.7
25
24
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
+∞
13.7
13
*
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
+∞
13.7
13
*
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
28.1
13.6
18
7
IAB14
NOMESCO Finland
Geriatric psychiatry consultation
149.9
13.6
14
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
6.4
13.6
24
42
Z2446
NOMESCO Finland
Social worker
5.4
13.6
29
61
N06AB10
ATC
escitalopram; oral
3.6
13.1
52
177
SPAT1216
SPAT
Assessment of functional ability
3.5
13.0
55
195
IGY02
NOMESCO Finland
Psychiatric monitoring contact
18.9
12.8
19
11
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
+∞
12.6
12
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.1
12.6
29
65
ZY000
NOMESCO Finland
Hospital inpatient
28.8
12.3
16
6
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
23.1
12.2
17
8
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
4.4
11.8
33
87
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.4
11.8
33
87
IGY99
NOMESCO Finland
Other psychiatric treatment contact
69.2
11.7
13
*
F05.9
ICD-10 Finland
Delirium, unspecified
18.4
11.4
17
10
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.1
11.2
60
243
R41.3
ICD-10 Finland
Other amnesia
9.4
10.9
22
26
A04
ICPC
Weakness/tiredness general
3.4
10.7
45
157
IBZ07
NOMESCO Finland
Neurological assessment in psychiatry
115.9
10.5
11
*
F0202, G310,
ICD-10 Finland
+∞
10.5
10
*
RT250, ,
NOMESCO Finland
+∞
10.5
10
*
F02.00
ICD-10 Finland
Dementia in Pick's disease without additional symptoms
+∞
10.5
10
*
F0201, G310,
ICD-10 Finland
+∞
10.5
10
*
G30.8
ICD-10 Finland
Other Alzheimer disease
+∞
10.5
10
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
0.1
10.3
7
401
N05AD01
ATC
haloperidol; systemic
10.0
10.3
20
22
N99
ICPC
Neurological disease other
42.4
10.1
12
*
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
57.9
9.7
11
*
Z2221
NOMESCO Finland
Medical doctor
2.7
9.6
71
340
N05AX12
ATC
aripiprazole; systemic
13.3
9.5
16
13
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
31.8
9.5
12
*
F22.0
ICD-10 Finland
Delusional disorder
23.0
9.5
13
6
RT150, ,
NOMESCO Finland
+∞
9.4
9
*
F06.4
ICD-10 Finland
Organic anxiety disorder
+∞
9.4
9
*
R41.0
ICD-10 Finland
Disorientation, unspecified
7.4
9.1
21
31
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
9.0
93
519
F29
ICD-10 Finland
Unspecified nonorganic psychosis
10.2
9.0
17
18
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
15.0
8.8
14
10
N06AB04
ATC
citalopram; systemic
2.7
8.5
57
257
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
13.6
8.5
14
11
ZXE21
NOMESCO Finland
Procedure duration at least 3 but less than 4 hours
+∞
8.4
8
*
G30.0
ICD-10 Finland
Alzheimer disease with early onset
+∞
8.4
8
*
N06AX16
ATC
venlafaxine; oral
3.2
8.3
37
133
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
8.7
8.3
17
21
N05CD07
ATC
temazepam; oral
3.0
8.3
41
157
Z3226
NOMESCO Finland
Physiotherapist
2.8
8.3
52
227
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
12.5
8.2
14
12
-, ,
ICD-10 Finland
10.0
7.9
15
16
P99
ICPC
Psychological disorders other
11.5
7.9
14
13
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
4.4
7.7
20
49
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.4
7.7
82
458
ZYB04
NOMESCO Finland
Outreach service in patient’s home or everyday environment
83.1
7.5
8
*
P28
ICPC
Limited function/disability (P)
83.1
7.5
8
*
N05AN01
ATC
lithium; oral
11.5
7.4
13
12
Z3231
NOMESCO Finland
Registered nurse
2.4
7.4
72
385
F064, G310,
ICD-10 Finland
+∞
7.3
7
*
N03AX09
ATC
lamotrigine; oral
7.0
7.3
17
26
L28
ICPC
Limited function/disability (L)
2.6
7.2
49
221
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
31.3
7.2
9
*
N06AX26
ATC
vortioxetine; oral
5.9
7.1
19
35
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.1
7.0
18
32
N05BA01
ATC
diazepam; systemic, rectal
2.8
6.9
40
166
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
17.4
6.8
10
6
IGV01
NOMESCO Finland
Psychiatric network contact
41.5
6.8
8
*
ZXY01
NOMESCO Finland
Chief Physician, Head of Department or Deputy Chief Physician
41.5
6.8
8
*
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
12.9
6.7
11
9
SPAT1294
SPAT
Other function in accordance with health social work nomenclature
9.2
6.7
13
15
ZXY02
NOMESCO Finland
Neuropsychologist
72.1
6.5
7
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.9
6.4
19
52
R53
ICD-10 Finland
Malaise and fatigue
2.3
6.3
58
299
F01.9
ICD-10 Finland
Vascular dementia, unspecified
+∞
6.3
6
*
F020, G310,
ICD-10 Finland
+∞
6.3
6
*
F060, G310,
ICD-10 Finland
+∞
6.3
6
*
F02.01
ICD-10 Finland
Dementia in Pick's disease has other additional symptoms, mainly paranoidism
+∞
6.3
6
*
SPAT1053
SPAT
Memory test
2.6
6.2
41
182
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
5.9
6.1
16
29
SPAT1101
SPAT
Orthostatic test
4.1
6.1
17
44
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
10.5
6.1
11
11
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
10.5
6.1
11
11
U04
ICPC
Incontinence urine
3.7
6.0
20
59

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
39
29
16.52
42.91
1.1
1.1
1.81
3.74
e6/l
1.54
26
23
38
29
16.00
41.15
1.1
1.3
153.93
117.04
e6/l
0.13
27
23
83
319
3.77
18.00
2.0
1.7
1302.80
1189.01
nmol/l
0.53
65
237
20
10
22.06
14.10
1.4
1.1
—
—
—
0
0
24
27
9.96
12.16
1.2
1.2
—
—
—
0
0
115
675
2.69
10.46
2.7
2.0
91.08
96.56
pmol/l
0.70
65
344
15
11
14.64
9.34
1.0
1.1
—
—
—
0
0
67
328
2.58
8.49
3.1
3.3
2.45
2.46
mmol/l
0.44
52
283
96
558
2.41
8.35
2.6
3.4
2.35
2.35
mmol/l
0.14
80
494
76
401
2.46
8.17
1.8
1.5
19.37
20.99
nmol/l
0.44
70
337
90
518
2.36
7.90
3.6
4.0
7.39
7.40
ph
0.24
13
106
75
402
2.40
7.71
3.9
4.0
88.91
87.17
%
0.23
70
394
38
155
2.80
6.78
2.5
2.5
35.15
36.59
u/l
0.06
33
125
113
759
2.15
6.38
7.0
5.8
1.21
1.21
mmol/l
0.11
101
692
65
356
2.23
6.14
4.4
3.7
—
—
—
0
0
70
406
2.12
5.66
6.3
6.7
—
—
—
0
0
20
490
0.34
5.28
2.4
3.5
—
—
—
0
0
15
35
4.55
4.74
1.0
1.3
—
—
—
0
0
114
831
1.88
4.49
7.2
6.6
1.21
1.21
mmol/l
0.24
94
706
74
473
1.90
4.36
3.7
3.3
—
—
—
0
0
101
714
1.85
4.34
4.1
4.8
35.66
35.17
g/l
0.39
89
674
50
284
2.02
4.13
2.8
3.2
6.96
2.80
e6/l
0.61
22
160
0
96
0.00
3.78
0.0
4.2
—
—
—
0
0
31
153
2.22
3.65
4.9
7.9
—
—
—
0
0
8
13
6.36
3.53
1.4
1.1
—
—
—
0
0
8
13
6.36
3.53
1.4
1.1
—
—
—
0
0
8
14
5.91
3.37
1.4
1.1
—
—
—
0
0
8
14
5.91
3.37
1.4
1.1
—
—
—
0
0
8
14
5.91
3.37
1.4
1.1
—
—
—
0
0
15
54
2.92
3.33
4.2
3.7
—
—
—
0
0
73
498
1.74
3.32
3.8
3.4
0.25
0.54
e6/l
1.07
56
374
74
508
1.73
3.29
3.9
3.2
—
—
—
0
0
22
430
0.45
3.20
4.0
3.9
—
—
—
0
0
12
35
3.58
3.17
1.1
1.3
—
—
—
0
0
17
68
2.64
3.13
2.1
3.3
4.04
4.36
pmol/l
0.34
11
62
6
8
7.69
3.07
1.2
1.1
—
—
—
0
0
7
12
6.00
3.05
1.1
1.1
—
—
—
0
0
74
517
1.69
3.04
2.6
2.0
415.52
236.62
u/l
0.59
66
481
33
546
0.52
2.91
3.3
4.2
—
—
—
0
0
6
9
6.83
2.89
1.8
1.1
—
—
—
0
0
143
1208
1.67
2.62
30.5
21.5
330.52
331.68
g/l
0.70
136
1202
37
575
0.56
2.58
3.2
3.9
5.44
10.04
mg/mmol
0.99
26
361
16
71
2.36
2.41
16.0
3.9
—
—
—
0
0
0
60
0.00
2.29
0.0
4.4
—
—
—
0
0
74
550
1.55
2.25
3.7
3.5
31.42
176.49
e6/l
0.66
54
425
35
215
1.76
2.23
10.1
7.0
0.89
0.95
mmol/l
0.02
28
175
57
404
1.58
2.11
2.7
2.0
3.27
3.15
mg/l
0.07
50
356
80
612
1.52
2.11
4.4
4.0
105.68
89.86
e6/l
0.10
58
452
37
541
0.61
1.96
2.9
3.4
27.84
173.93
mg/l
0.69
27
357
43
293
1.60
1.87
2.9
3.3
0.81
0.82
mmol/l
0.12
36
275
50
358
1.53
1.75
3.0
3.1
532.20
540.92
mosm/kgh2o
0.11
45
302
65
492
1.48
1.75
4.9
4.3
—
—
—
0
0
130
1129
1.45
1.64
5.6
3.9
13.98
15.03
pmol/l
4.59
117
994
23
139
1.74
1.57
4.1
3.3
—
—
—
0
0
125
1086
1.41
1.52
4.9
4.5
—
—
—
0
0
40
545
0.67
1.48
2.8
3.2
7.90
7.20
mmol/l
0.49
35
443
17
95
1.86
1.48
5.1
5.9
26.41
24.64
mmol/l
1.15
17
95
11
209
0.50
1.45
1.0
1.3
—
—
—
0
0
27
176
1.62
1.41
3.2
2.4
8.18
9.09
ug/l
0.08
20
157
50
647
0.70
1.40
1.9
2.2
—
—
—
0
0
49
366
1.45
1.39
1.4
1.8
452.41
443.20
pmol/l
0.08
39
302
7
147
0.46
1.39
1.7
4.1
—
0.16
—
0
55
0
39
0.00
1.35
0.0
2.6
—
—
—
0
0
136
1493
0.71
1.35
5.9
6.7
39.82
41.03
mmol/mol
0.69
126
1374
26
380
0.64
1.34
1.3
1.3
—
—
—
0
0
34
238
1.52
1.32
11.8
6.4
106.03
103.86
mmol/l
2.23
34
238
26
174
1.57
1.23
1.7
1.6
—
—
—
0
0
5
19
2.67
1.22
1.2
1.6
159.60
296.89
mu/l
—
5
19
14
233
0.57
1.21
1.4
1.3
—
—
—
0
0
154
1414
1.41
1.17
6.5
4.7
2.74
2.02
mu/l
0.64
135
1249
0
33
0.00
1.17
0.0
2.6
—
4.02
—
0
33
0
33
0.00
1.17
0.0
2.6
—
106.03
—
0
33
140
1519
0.73
1.16
3.9
5.0
1.40
1.45
mmol/l
0.69
121
1370
0
35
0.00
1.16
0.0
1.3
—
—
—
0
0
7
138
0.49
1.14
1.7
4.2
—
0.04
—
0
46
7
138
0.49
1.14
1.7
3.8
—
0.41
—
0
49
21
136
1.61
1.14
3.1
3.3
83.29
82.36
ng/l
0.02
14
122
5
21
2.42
1.09
5.4
2.8
—
—
—
0
0
8
150
0.51
1.08
1.5
1.5
—
—
—
0
0
143
1541
0.74
1.07
4.9
5.2
6.21
6.13
mmol/l
0.23
130
1391
140
1274
1.34
1.07
7.0
8.0
81.42
80.86
u/l
0.05
123
1194
19
123
1.60
1.04
12.0
4.1
—
—
—
0
0
12
68
1.81
1.03
2.4
2.1
42.07
37.28
g/l
—
6
60
142
1528
0.75
1.01
4.0
5.0
4.58
4.52
mmol/l
0.28
122
1391
0
30
0.00
0.98
0.0
3.0
—
60.00
—
0
30
105
927
1.28
0.96
8.4
9.4
4.74
4.17
e9/l
1.12
89
803
137
1478
0.76
0.96
3.5
4.5
1.43
1.27
mmol/l
1.31
116
1328
0
32
0.00
0.96
0.0
2.7
—
—
—
0
0
54
437
1.32
0.94
5.5
4.2
0.00
0.00
estimate
—
9
144
17
251
0.65
0.92
1.3
1.3
20.88
47.74
iu/ml
—
5
94
18
261
0.66
0.90
1.9
1.8
—
—
—
0
0
147
1564
0.76
0.85
4.7
5.7
2.68
2.63
mmol/l
0.24
129
1416
13
81
1.65
0.83
1.1
1.3
—
28.80
—
0
5
41
325
1.33
0.83
4.0
3.7
58.81
149.77
ng/l
1.39
36
274
90
793
1.25
0.79
4.9
5.8
1.66
1.98
e9/l
1.21
76
703
16
231
0.67
0.79
1.5
1.3
1.88
15.07
u/ml
—
6
89
0
28
0.00
0.76
0.0
1.1
—
—
—
0
0
0
28
0.00
0.76
0.0
2.8
—
4.58
—
0
28
13
84
1.59
0.74
2.5
2.4
—
—
—
0
0
88
779
1.23
0.73
4.9
5.7
0.60
0.60
e9/l
0.00
71
664
162
1535
1.31
0.72
20.4
16.1
31.08
25.48
mg/l
1.11
121
1238
125
1150
1.24
0.72
4.0
4.3
—
—
—
0
0
7
41
1.73
0.70
1.3
2.3
—
—
—
0
0
88
783
1.22
0.69
4.9
5.7
0.04
0.04
e9/l
0.26
73
668
5
95
0.51
0.68
1.2
1.2
—
—
—
0
0
5
28
1.81
0.66
2.6
1.1
—
—
—
0
0
90
806
1.21
0.65
6.4
5.8
0.20
0.19
e9/l
0.11
77
702
87
780
1.21
0.62
5.3
5.4
0.00
0.00
estimate
—
10
156
0
20
0.00
0.60
0.0
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
38
456
0.79
0.60
2.2
3.0
356.36
7118.81
umol/l
1.96
25
378
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
0
22
0.00
0.59
0.0
4.0
—
—
—
0
0
0
23
0.00
0.58
0.0
2.7
—
—
—
0
0
106
974
1.19
0.56
7.7
4.8
7.19
6.86
mmol/l
0.78
94
916
86
776
1.19
0.56
4.5
4.0
0.00
0.01
estimate
—
10
166
11
158
0.68
0.55
4.4
4.1
—
—
—
0
0
87
787
1.19
0.55
4.4
4.0
0.00
0.00
estimate
—
9
148
9
132
0.67
0.54
1.4
1.3
—
—
—
0
0
26
208
1.29
0.51
1.7
3.0
1.61
1.72
%
0.28
21
189
23
182
1.30
0.49
2.0
3.4
7.89
9.01
umol/l
0.14
18
160
158
1639
0.82
0.48
23.3
19.7
75.97
82.35
umol/l
2.60
158
1639
65
580
1.18
0.47
2.8
2.6
94.23
155.70
ug/l
2.89
56
530
7
48
1.47
0.47
1.4
1.6
—
—
—
0
0
76
690
1.17
0.44
4.1
4.1
27.59
42.89
ng/l
1.26
57
550
16
206
0.76
0.44
1.3
1.4
—
—
—
0
0
16
206
0.76
0.44
1.2
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
40806.67
—
0
9
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
1019.62
—
0
13
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
139.03
—
0
6
0
19
0.00
0.39
0.0
4.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
9
66
1.38
0.39
1.2
1.3
—
—
—
0
0
19
153
1.27
0.37
1.0
1.4
—
—
—
0
0
10
134
0.73
0.36
1.4
1.4
—
—
—
0
0
97
908
1.13
0.36
4.7
6.6
10.21
11.68
umol/l
1.03
88
863
6
45
1.34
0.34
2.8
4.0
—
—
—
0
0
65
706
0.88
0.32
4.7
5.2
2.17
2.87
ug/l
0.47
55
625
78
727
1.12
0.30
5.2
5.9
59.77
58.17
%
0.51
71
685
168
1638
1.17
0.30
27.0
19.1
139.69
139.68
mmol/l
0.02
158
1597
163
1586
1.16
0.29
17.4
15.1
—
—
—
0
0
11
140
0.77
0.29
1.4
1.3
—
—
—
0
0
7
57
1.24
0.29
1.3
1.2
—
—
—
0
0
7
57
1.24
0.29
10.4
11.3
—
—
—
0
0
168
1643
1.15
0.25
26.0
19.2
3.95
4.00
mmol/l
1.64
158
1604
75
704
1.11
0.25
5.3
5.9
0.68
0.63
%
0.37
67
659
16
134
1.21
0.23
2.1
2.4
—
—
—
0
0
78
736
1.10
0.23
5.2
6.2
25.41
26.51
%
0.37
70
693
77
727
1.10
0.22
8.4
10.8
0.00
0.00
e9/l
0.58
59
591
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
193.71
—
0
10
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
2.4
—
—
—
0
0
0
13
0.00
0.21
0.0
2.3
—
—
—
0
0
0
13
0.00
0.21
0.0
3.9
—
25.78
—
0
5
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
6
48
1.26
0.20
1.2
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.4
—
8.56
—
0
14
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
25
280
0.88
0.20
1.6
1.4
2.17
2.42
g/l
0.31
13
168
6
52
1.16
0.19
1.0
1.1
—
—
—
0
0
77
733
1.08
0.18
4.6
6.5
—
—
—
0
0
76
724
1.08
0.18
5.2
5.9
2.87
2.76
%
0.17
68
679
12
141
0.84
0.17
5.8
4.0
—
—
—
0
0
29
264
1.12
0.17
1.4
2.2
2.28
2.29
g/l
0.05
21
243
76
726
1.08
0.16
5.3
6.3
8.97
8.80
%
0.21
67
682
7
85
0.82
0.15
2.6
3.2
—
—
—
0
0
31
287
1.10
0.13
1.5
2.2
11.30
13.26
umol/l
0.90
24
264
162
1643
0.92
0.12
12.0
11.6
23.98
25.62
u/l
0.74
152
1574
119
1162
1.06
0.12
3.1
4.4
12.35
14.02
mm/h
0.61
108
1054
12
135
0.88
0.10
1.3
1.5
—
—
—
0
0
54
518
1.06
0.10
2.7
2.5
45.06
67.30
u/l
1.72
47
479
38
361
1.07
0.09
1.9
1.8
1.35
1.45
mg/l
0.10
28
289
88
859
1.04
0.08
12.0
15.4
1.07
1.33
inr
4.76
15
267
42
402
1.06
0.08
2.5
3.1
0.96
0.83
ug/l
0.14
36
279
9
88
1.02
0.07
4.4
2.3
0.64
0.68
%
—
9
88
29
305
0.94
0.07
1.4
1.2
0.59
1.43
u/ml
—
7
80
17
160
1.07
0.04
2.1
2.9
67.34
66.80
g/l
—
10
144
167
1677
0.97
0.01
30.7
23.6
6.96
6.78
e9/l
0.45
158
1617
167
1677
0.97
0.01
30.5
23.5
91.75
91.66
fl
0.10
159
1650
167
1677
0.97
0.01
30.7
23.8
132.08
134.94
g/l
1.49
159
1647
167
1677
0.97
0.01
30.5
23.5
30.35
30.45
pg
0.28
159
1650
167
1677
0.97
0.01
30.8
23.8
39.77
40.02
%
0.24
156
1573
167
1677
0.97
0.01
30.6
23.6
4.36
4.46
e12/l
1.67
158
1618
167
1676
0.98
0.00
30.6
23.6
246.54
241.61
e9/l
0.42
158
1625
14
141
0.99
0.00
1.6
2.8
139.57
229.23
ng/l
0.71
14
125
50
504
0.99
0.00
2.4
2.5
—
—
—
0
0
132
1324
0.99
0.00
27.5
19.2
14.75
15.38
%
0.71
127
1305
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
6.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
4.43
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
6.1
—
41.57
—
0
7
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
85.13
—
0
8
0
9
0.00
-0.00
0.0
1.7
—
14.76
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
78.63
—
0
8
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
87
0.92
-0.00
1.3
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
18.60
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
41.00
—
0
5
0
8
0.00
-0.00
0.0
1.6
—
1.06
—
0
8
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
9
90
1.00
-0.00
4.4
2.3
1.36
1.13
%
—
9
90
9
92
0.98
-0.00
1.2
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
7.20
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: FTD – Frontotemporal dementia

GWS hits: 2

This endpoint is excluded (different definition than used in FinnGen).