No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
173 |
4. Check minimum number of eventsNone |
173 |
5. Include endpointsNone |
173 |
6. Filter based on genotype QC (FinnGen only) |
169 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
- Parent code in ICD-10
- K22
- Name in latin
- Ulcus oesophagi
Similar endpoints
↥List of similar endpoints to
Ulcer of oesophagus, drug-induced
based on the number of shared cases.
Similar with more cases:
- Ulcer of oesophagus
- Diseases of oesophagus, stomach and duodenum
- Gastrointestinal diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (not available in FinRegistry).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 169 | 50 | 119 |
| Unadjusted period prevalence (%) | 0.04 | 0.02 | 0.05 |
| Median age at first event (years) | 57.65 | 55.56 | 58.52 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 173
- Matched controls
- 1730
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K22.1
ICD-10 Finland
Ulcer of oesophagus
+∞
220.5
173
23
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
13.6
64.6
81
105
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
8.8
43.4
123
378
A02BC01
ATC
omeprazole; systemic
8.2
42.1
117
350
A02BC03
ATC
lansoprazole; oral
7.6
38.9
116
365
UJD02
NOMESCO Finland
Gastroscopy
11.5
38.5
46
53
K22.7
ICD-10 Finland
Barrett oesophagus
35.9
23.7
30
10
A02BA04
ATC
nizatidine; systemic
6.8
22.4
41
76
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
6.0
19.1
39
80
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
22.6
18.9
27
14
A02BA02
ATC
ranitidine; systemic
3.7
15.2
73
288
A02BA03
ATC
famotidine; systemic
6.6
14.4
25
43
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
4.9
12.9
32
77
A03FA02
ATC
cisapride; oral, rectal
4.6
11.8
31
78
6241
FHL
Fund application (Nissen)
34.9
10.5
13
*
XJC10
NOMESCO Finland
Oesophageal pH monitoring
+∞
9.5
9
*
-, ,
ICD-10 Finland
12.5
8.8
15
13
5301B
ICD-9 Finland
Diseases of oesophagus, Oesophagitis[BARRETT'S OESOPHAGUS]
94.5
8.5
9
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
7.8
70
366
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
47.1
7.8
9
*
N06AA09
ATC
amitriptyline; systemic
3.6
7.5
26
80
5308A
ICD-9 Finland
Diseases of oesophagus, Other specified disorders of oesophagus[HERNIA HIATUS OESOPHAGI (""""SLIDING HERNIA"""")]
31.5
7.2
9
*
A02BC05
ATC
esomeprazole; systemic
2.4
7.1
83
486
JBC00
NOMESCO Finland
Gastro-oesophageal antireflux operation
23.6
6.7
9
*
J01DA01
ATC
[U] cefalexin
2.4
6.5
117
813
C03CA01
ATC
furosemide; systemic
2.2
6.4
94
599
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
6.2
74
432
N05CF01
ATC
zopiclone; oral
2.2
6.0
74
435
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
49
223
2.67
7.22
2.7
2.5
20.06
22.77
%
0.65
37
195
49
231
2.56
6.67
2.8
2.5
2.35
2.24
g/l
0.68
49
211
55
281
2.40
6.26
4.2
4.0
26.94
320.45
ng/l
1.98
47
245
38
178
2.45
5.15
2.4
1.8
—
—
—
0
0
91
616
2.01
4.82
6.5
4.6
33.58
34.53
g/l
0.71
84
576
37
178
2.37
4.71
2.3
1.7
—
—
—
0
0
62
369
2.06
4.67
2.6
2.0
3.16
3.12
mg/l
0.05
54
317
37
185
2.27
4.30
6.7
5.6
2.87
0.85
mmol/l
3.15
30
150
60
369
1.96
4.04
1.8
1.7
16.37
21.14
nmol/l
1.84
53
304
73
497
1.81
3.50
3.6
2.6
140.75
170.64
ug/l
0.63
66
446
113
889
1.78
3.20
6.4
4.8
413.14
3246.22
e6/l
—
7
23
74
519
1.74
3.13
3.3
3.5
—
—
—
0
0
56
363
1.80
3.09
6.3
4.5
0.00
0.00
estimate
-0.00
11
126
85
626
1.70
2.97
5.9
5.4
0.00
0.00
estimate
-0.00
15
129
85
628
1.69
2.93
5.2
4.1
0.00
0.00
estimate
-0.00
15
145
85
636
1.66
2.74
5.3
4.1
0.00
0.00
estimate
-0.00
13
123
6
10
6.17
2.72
1.7
1.9
13.17
12.80
u/l
—
6
10
41
254
1.80
2.59
2.4
1.9
—
—
—
0
0
64
452
1.66
2.53
3.9
3.3
2.32
2.34
mmol/l
0.58
58
395
43
272
1.77
2.53
1.6
1.7
1.98
1.50
mg/l
0.25
34
215
31
177
1.92
2.52
2.1
3.9
220.96
247.54
u/l
1.14
25
168
0
65
0.00
2.48
0.0
2.0
—
—
—
0
0
77
580
1.59
2.31
2.3
2.1
85.71
92.73
pmol/l
0.54
37
296
92
724
1.58
2.28
11.8
8.8
4.19
4.34
e9/l
0.24
81
624
0
62
0.00
2.27
0.0
1.8
—
—
—
0
0
9
30
3.11
2.18
1.8
1.5
—
—
—
0
0
90
712
1.55
2.13
9.4
6.3
1.20
1.21
mmol/l
0.12
78
587
67
496
1.57
2.13
5.8
4.4
—
—
—
0
0
19
97
2.08
2.10
2.2
1.3
—
—
—
0
0
8
26
3.17
2.04
1.6
1.5
—
—
—
0
0
9
32
2.91
2.03
1.9
1.5
—
—
—
0
0
84
661
1.53
2.00
9.0
5.5
1.21
1.21
mmol/l
0.06
79
583
27
159
1.83
2.00
5.0
4.0
—
—
—
0
0
20
108
1.96
1.91
2.3
1.6
—
—
—
0
0
93
756
1.50
1.85
22.3
17.2
1.29
1.39
inr
0.57
30
215
6
17
3.62
1.85
1.3
1.5
—
—
—
0
0
9
35
2.66
1.83
1.4
1.2
—
—
—
0
0
12
54
2.31
1.78
3.2
2.8
—
—
—
0
0
6
18
3.41
1.76
2.3
1.5
—
—
—
0
0
6
18
3.41
1.76
2.3
1.5
—
—
—
0
0
72
563
1.48
1.70
2.6
2.3
—
—
—
0
0
99
825
1.47
1.68
7.7
4.7
6.70
6.94
mmol/l
0.75
93
782
10
41
2.53
1.67
1.8
1.5
—
—
—
0
0
10
41
2.53
1.67
1.8
1.5
—
—
—
0
0
69
541
1.46
1.59
5.0
3.5
1672.19
1804.93
ng/l
0.16
62
458
44
315
1.53
1.57
1.7
1.7
1158.06
1221.23
nmol/l
0.20
35
238
117
1019
1.46
1.50
11.0
7.5
85.69
79.94
u/l
0.49
112
944
102
869
1.42
1.46
4.2
3.6
15.37
15.02
pmol/l
0.61
88
737
7
29
2.47
1.40
1.6
1.7
—
—
—
0
0
6
25
2.45
1.25
2.3
1.7
—
—
—
0
0
6
25
2.45
1.25
2.3
1.7
—
—
—
0
0
6
25
2.45
1.25
1.7
1.5
—
—
—
0
0
5
19
2.68
1.22
1.2
1.3
—
—
—
0
0
6
26
2.35
1.19
1.3
1.3
—
—
—
0
0
56
444
1.39
1.16
3.6
3.9
13.34
10.20
mg/mmol
0.23
38
292
72
597
1.35
1.13
3.6
2.5
—
—
—
0
0
8
41
2.00
1.10
1.0
1.6
—
—
—
0
0
21
138
1.59
1.09
3.5
3.6
0.97
1.67
mmol/l
0.23
16
107
122
1100
1.37
1.08
4.8
4.5
1.90
2.12
mu/l
1.05
107
953
16
98
1.70
1.07
5.3
3.3
46.38
54.18
ml/min/173m2
—
8
39
21
140
1.57
1.03
3.5
3.6
5.58
5.68
kpa
0.14
21
134
32
235
1.44
1.01
2.5
2.8
1.24
1.04
e6/l
0.22
16
138
36
271
1.41
1.00
3.8
3.1
2.47
2.46
mmol/l
0.11
30
241
19
125
1.58
0.99
2.3
2.0
317.21
386.94
nmol/l
0.85
14
109
50
399
1.36
0.99
3.3
3.3
0.86
0.50
e6/l
0.32
40
306
5
23
2.21
0.98
3.4
2.4
61.20
57.91
%
—
5
23
6
27
2.26
0.94
1.7
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
9
52
1.77
0.94
4.0
1.9
0.38
0.36
u/ml
—
9
29
6
30
2.03
0.88
2.0
1.5
—
—
—
0
0
31
233
1.40
0.87
2.9
3.1
2.24
1.30
e6/l
0.48
17
137
31
398
0.73
0.82
3.0
3.1
0.74
0.77
ug/l
0.06
22
272
8
47
1.74
0.82
1.9
1.3
—
—
—
0
0
0
27
0.00
0.78
0.0
1.7
—
4.77
—
0
20
7
43
1.65
0.67
1.3
1.5
—
—
—
0
0
7
44
1.62
0.66
1.0
1.0
—
—
—
0
0
131
1235
1.25
0.58
30.0
17.4
26.50
26.20
mg/l
0.03
113
1027
109
1165
0.83
0.55
27.4
17.2
72.07
72.07
ml/min/173m2
0.00
84
973
70
626
1.20
0.52
5.9
4.4
60.82
53.42
ng/l
0.11
49
490
101
935
1.19
0.51
5.3
4.2
17.19
14.08
mm/h
1.10
96
850
6
43
1.41
0.35
1.7
1.4
—
—
—
0
0
134
1289
1.18
0.35
33.7
21.3
87.65
86.79
umol/l
0.08
134
1289
60
553
1.13
0.28
7.4
4.7
22.78
21.09
%
0.32
30
278
133
1288
1.14
0.27
15.1
11.1
24.91
24.26
u/l
0.16
125
1234
6
81
0.73
0.24
1.0
1.3
—
—
—
0
0
114
1182
0.90
0.24
5.0
4.9
4.24
4.33
mmol/l
0.46
105
1062
29
325
0.87
0.23
2.3
2.2
—
—
—
0
0
5
38
1.32
0.23
2.2
1.1
—
—
—
0
0
5
38
1.32
0.23
2.2
1.1
—
—
—
0
0
5
40
1.26
0.22
3.2
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
7.60
—
0
5
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
123
1193
1.11
0.21
5.7
5.2
6.07
6.20
mmol/l
0.66
111
1061
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
20
174
1.17
0.21
24.6
9.0
—
—
—
0
0
13
109
1.21
0.19
1.5
1.3
—
—
—
0
0
19
166
1.16
0.19
1.3
1.3
14.13
38.60
iu/ml
1.97
12
60
24
217
1.12
0.15
1.2
1.2
1.32
0.91
u/ml
—
6
62
136
1336
1.08
0.13
42.0
25.4
37.68
39.56
%
1.73
118
1236
17
152
1.13
0.12
1.2
1.3
1.25
26.43
u/ml
—
6
49
33
308
1.09
0.12
1.8
1.7
1.60
1.31
mmol/l
0.55
26
244
115
1175
0.94
0.12
4.7
4.9
1.42
1.40
mmol/l
0.12
106
1041
18
163
1.12
0.11
3.3
4.6
4.21
74.33
ug/l
0.85
18
139
112
1144
0.94
0.11
4.3
4.4
1.38
1.26
mmol/l
0.92
104
1009
5
46
1.09
0.09
2.2
1.2
—
—
—
0
0
22
204
1.09
0.09
11.8
5.4
104.55
103.96
mmol/l
0.21
22
204
5
62
0.80
0.08
1.0
2.2
0.00
0.00
g/l
—
5
56
69
710
0.95
0.08
6.6
5.4
5.33
2.65
ug/l
0.39
64
618
6
71
0.84
0.08
1.0
2.0
2.33
2.96
g/l
—
6
61
120
1218
0.95
0.07
5.5
5.5
2.30
2.51
mmol/l
2.03
107
1084
8
77
1.04
0.07
4.1
2.0
7.14
7.36
g/l
—
8
67
8
77
1.04
0.07
4.1
2.0
—
—
—
0
0
8
77
1.04
0.07
4.1
2.0
2.91
3.56
g/l
—
8
67
10
94
1.07
0.01
1.6
1.7
—
—
—
0
0
115
1154
0.99
0.00
7.8
6.9
41.39
41.59
mmol/mol
0.09
107
1061
12
117
1.03
0.00
5.0
2.8
4.56
4.28
kpa
0.27
12
111
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
14.79
—
0
8
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
6
60
1.00
-0.00
1.5
3.2
—
1.44
—
0
5
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
12.03
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
-0.00
4.6
2.0
11.04
10.87
g/l
—
7
60
0
7
0.00
-0.00
0.0
2.3
—
1042.57
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (not available in FinRegistry).
Relationships between endpoints
↥Index endpoint: K11_OESULC_ADVERSE – Ulcer of oesophagus, drug-induced
GWS hits: -
This endpoint is excluded (not available in FinRegistry).