femoral neuropathy: Neuropathy of the femoral nerve.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
285 |
4. Check minimum number of eventsNone |
285 |
5. Include endpointsNone |
285 |
6. Filter based on genotype QC (FinnGen only) |
277 |
Control definitions (FinnGen only)
- Control exclude
- G6_NERPLEX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G57
- Name in latin
- Morbositas nervi femoralis
Similar endpoints
↥List of similar endpoints to
Lesion of femoral nerve
based on the number of shared cases.
Similar with more cases:
- Nerve, nerve root and plexus disorders
- Neurological diseases
- Neurological diseases, wide definition
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1898 | 1197 | 693 |
| Only index persons | 1739 | 1132 | 607 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.02 |
| Only index persons | 0.04 | 0.04 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 52.40 | 52.31 | 52.41 |
| Only index persons | 51.40 | 51.82 | 50.61 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 277 | 205 | 72 |
| Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.03 |
| Median age at first event (years) | 50.00 | 50.16 | 49.55 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 285
- Matched controls
- 2850
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G57.2
ICD-10 Finland
Lesion of femoral nerve
4503599627370496.0
307.7
270
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
6.9
50.8
102
212
N03AX16
ATC
[U] pregabalin
5.6
44.9
129
368
N03AX12
ATC
[U] gabapentin; oral
6.0
44.1
103
244
G56.0
ICD-10 Finland
Carpal tunnel syndrome
12.5
42.8
45
42
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
6.3
37.4
76
156
M54.4
ICD-10 Finland
Lumbago with sciatica
4.7
32.4
100
292
N02AX02
ATC
tramadol; systemic, rectal
4.2
30.9
178
811
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
173.2
30.3
31
*
M54.1
ICD-10 Finland
Radiculopathy
10.0
28.3
34
38
M48.0
ICD-10 Finland
Spinal stenosis
4.9
26.7
70
177
N06AX21
ATC
duloxetine; oral
4.9
26.6
71
182
M54.5
ICD-10 Finland
Low back pain
3.6
24.9
152
693
N06AA09
ATC
amitriptyline; systemic
4.6
21.4
59
154
M79.6
ICD-10 Finland
Pain in limb
3.2
20.4
163
845
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.2
20.3
146
712
M70.6
ICD-10 Finland
Trochanteric bursitis
3.9
20.3
74
237
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
5.8
20.2
40
78
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.8
19.0
70
225
G57.1
ICD-10 Finland
Meralgia paraesthetica
23.7
18.5
26
12
L86
ICPC
Back syndrome with radiating pain
5.4
17.9
38
79
XA402
NOMESCO Finland
ENMG
14.5
17.4
29
22
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
5.0
16.7
39
88
M54.3
ICD-10 Finland
Sciatica
5.6
16.4
33
65
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.8
16.4
58
180
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.2
16.4
48
130
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.3
15.1
42
109
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
7.3
15.1
23
34
M01AX17
ATC
nimesulide; oral
2.9
15.1
99
445
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.8
15.0
109
516
N02BF01
ATC
gabapentin; oral
4.6
14.9
38
92
L14
ICPC
Leg/thigh symptom/complaint
4.3
14.7
42
111
3552A
ICD-9 Finland
Mononeuritis of lower limb, Other lesion of femoral nerve
+∞
14.7
14
*
L03
ICPC
Low back symptom/complaint
2.7
13.9
104
497
R52.9
ICD-10 Finland
Pain, unspecified
3.7
13.8
49
152
SPAT1216
SPAT
Assessment of functional ability
3.2
13.5
62
226
L01
ICPC
Neck symptom/complaint
3.1
12.8
64
245
L13
ICPC
Hip symptom/complaint
2.8
12.8
82
360
M03BX02
ATC
tizanidine; oral
2.7
12.5
209
1439
ACC51
NOMESCO Finland
Release of median nerve
135.7
12.5
13
*
M47.82
ICD-10 Finland
Other spondylosis, cervical region
5.3
12.4
26
53
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.6
12.2
95
458
SPAT1249
SPAT
Treatment-related counselling outside office
2.4
12.1
133
754
N06AX11
ATC
mirtazapine; oral
2.5
12.0
122
666
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
5.7
12.0
23
43
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
5.9
11.8
22
40
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
67.8
11.7
13
*
M25.5
ICD-10 Finland
Pain in joint
2.4
11.6
117
635
A02BA02
ATC
ranitidine; systemic
2.7
11.0
73
324
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
4.8
10.7
25
56
G57.8
ICD-10 Finland
Other mononeuropathies of lower limb
62.4
10.7
12
*
G57.0
ICD-10 Finland
Lesion of sciatic nerve
114.0
10.5
11
*
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.8
10.4
33
94
A02BC05
ATC
esomeprazole; systemic
2.3
10.4
140
851
N02AA05
ATC
oxycodone; systemic
2.7
10.3
63
267
A02BC02
ATC
pantoprazole; systemic
2.5
10.2
213
1550
Z01.8
ICD-10 Finland
Other specified special examinations
2.5
10.2
78
370
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.4
10.1
97
510
SPAT1130
SPAT
Esophagoscopy, gastroscopy and duodenoscopy
5.2
10.0
21
43
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.7
9.8
32
93
M03BC51
ATC
orphenadrine, combinations; systemic
2.3
9.7
105
579
M03BC01
ATC
orphenadrine (citrate); systemic
2.4
9.7
86
435
R52.2
ICD-10 Finland
Other chronic pain
5.1
9.7
21
44
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
103.3
9.5
10
*
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.9
9.3
48
185
R10.0
ICD-10 Finland
Acute abdomen
8.2
9.3
20
26
SPAT1310
SPAT
Counselling related to known health issue
2.2
9.2
109
621
A02BC03
ATC
lansoprazole; oral
2.2
9.2
101
559
SPAT1153
SPAT
Removal of sutures
2.2
9.2
104
583
N03AE01
ATC
clonazepam; systemic
4.0
9.0
26
69
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.7
9.0
21
47
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.9
9.0
27
74
R5599
NOMESCO Finland
Other rehabilitation service
9.1
8.9
18
21
L17
ICPC
Foot/toe symptom/complaint
2.2
8.9
99
550
H02AB06
ATC
prednisolone; systemic
2.1
8.8
150
981
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
4.6
8.8
21
48
L08
ICPC
Shoulder symptom/complaint
2.4
8.7
75
373
M01AH01
ATC
celecoxib; oral
2.4
8.7
68
324
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.8
8.6
49
199
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.9
8.5
19
41
SPAT1263
SPAT
Sampling
2.1
8.3
128
802
N02AJ06
ATC
codeine and paracetamol; systemic
2.1
8.3
137
881
M79.7
ICD-10 Finland
Fibromyalgia
4.8
8.2
19
42
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
4.1
8.1
23
60
G54.0
ICD-10 Finland
Brachial plexus disorders
34.4
8.1
10
*
RD211, ,
NOMESCO Finland
3.8
8.0
25
70
G44.2
ICD-10 Finland
Tension-type headache
2.6
8.0
54
239
G57.6
ICD-10 Finland
Lesion of plantar nerve
13.5
8.0
13
10
SPAT1229
SPAT
Assessment of need for aid
3.4
7.9
29
91
L02
ICPC
Back symptom/complaint
2.8
7.9
41
159
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.8
7.8
41
160
M01AB05
ATC
diclofenac; systemic, rectal
2.1
7.7
206
1563
J02AC01
ATC
fluconazole; systemic
2.0
7.6
140
926
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.0
7.5
146
984
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.9
7.5
37
139
M47.9
ICD-10 Finland
Spondylosis, unspecified
8.0
7.5
16
21
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.0
7.5
138
913
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
3.8
7.5
23
64
ACC19
NOMESCO Finland
Transcision of peripheral nerve: other or unspecified
82.1
7.5
8
*
SPAT1252
SPAT
Overall medication plan or its review
3.5
7.4
26
79
G58.9
ICD-10 Finland
Mononeuropathy, unspecified
+∞
7.3
7
*
M01AE03
ATC
ketoprofen; systemic, rectal
2.0
7.3
121
769
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.2
7.3
29
96
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.6
7.2
45
191
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
2.0
7.2
170
1220
M01AH03
ATC
valdecoxib; oral
3.7
7.2
23
66
SPAT1273
SPAT
Structured assessment of psychoactive substance / tobacco use
4.6
7.1
17
39
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.7
7.1
19
35
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
5.7
7.1
19
35
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.6
7.0
43
181
N05AH04
ATC
quetiapine; oral
2.4
7.0
57
274
WZC30
NOMESCO Finland
Teaching
2.3
7.0
57
275
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.2
6.9
67
348
J01AA02
ATC
doxycycline; systemic
2.3
6.8
237
1935
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
41.1
6.8
8
*
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.5
6.6
43
186
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.5
6.6
43
187
N06AX16
ATC
venlafaxine; oral
2.4
6.6
52
247
M01AH05
ATC
etoricoxib; oral
2.0
6.5
191
1451
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.2
6.4
17
42
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.3
6.4
56
277
TAB00
NOMESCO Finland
Lumbar puncture
3.8
6.4
20
56
M01AH02
ATC
rofecoxib; oral
2.5
6.4
45
202
SPAT1359
SPAT
Use of symptom diary
6.2
6.4
16
27
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.9
6.3
31
116
R42
ICD-10 Finland
Dizziness and giddiness
2.1
6.3
71
389
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
18.5
6.3
9
5
D07AC01
ATC
betamethasone; topical
1.9
6.3
107
679
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
6.3
93
563
35399
ICD-8 Finland
Sciatica
+∞
6.3
6
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
6.3
52
252
SPAT1260
SPAT
Consultation of another employee
2.2
6.2
60
309
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
6.0
6.2
16
28
M01AC06
ATC
meloxicam; systemic, rectal
1.9
6.2
121
802
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
8.0
6.2
13
17
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
3.9
6.2
18
48
M54.2
ICD-10 Finland
Cervicalgia
2.8
6.1
31
118
KHV, ,
NOMESCO Finland
12.9
6.1
10
8
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.1
6.1
72
401
RF420, ,
NOMESCO Finland
8.9
6.1
12
14
SAA02
NOMESCO Finland
Basic examination of mouth
1.9
6.1
197
1530
L15
ICPC
Knee symptom/complaint
2.0
6.1
81
472
SAA01
NOMESCO Finland
Simple examination of mouth
2.0
6.0
214
1711
N05CF01
ATC
zopiclone; oral
1.9
6.0
104
661
M54
ICD-10 Finland
Dorsalgia
2.6
6.0
38
162
M01AB55
ATC
diclofenac, combinations; oral
3.0
6.0
27
96
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
238
1885
2.59
8.47
5.5
3.9
14.91
14.77
pmol/l
0.37
227
1716
114
704
2.03
7.51
3.2
2.3
59.70
63.59
u/l
0.20
103
644
129
849
1.95
6.96
3.8
3.3
19.29
30.16
ng/l
1.12
78
569
101
622
1.97
6.53
4.4
3.6
0.00
0.00
estimate
-0.00
54
218
157
1137
1.85
6.03
6.3
6.4
1.22
1.22
mmol/l
0.38
142
968
193
1493
1.91
5.99
4.8
4.0
—
181.33
—
0
27
214
1743
1.91
5.30
5.6
3.9
12.88
11.94
mm/h
0.48
205
1589
258
2255
2.52
5.22
6.3
4.7
1.76
1.89
mu/l
1.31
244
2058
171
1323
1.73
4.80
4.8
4.6
6.78
6.56
mmol/l
0.70
165
1238
126
898
1.72
4.75
4.0
3.5
—
—
—
0
0
141
1038
1.71
4.72
10.8
10.4
1.12
1.19
inr
0.65
66
321
93
610
1.78
4.69
2.6
2.9
856.11
911.67
ng/l
0.09
80
520
151
1148
1.67
4.36
3.8
3.5
0.00
0.00
estimate
-0.00
55
237
18
62
3.03
4.25
1.3
1.3
1.22
1.20
g/l
0.11
18
57
10
17
6.05
4.16
3.1
1.4
—
—
—
0
0
135
1008
1.64
4.10
2.4
2.2
79.17
78.85
nmol/l
0.05
129
906
152
1173
1.63
4.02
3.9
3.5
0.00
0.01
estimate
0.50
52
220
151
1166
1.63
3.97
4.7
4.7
0.00
0.00
estimate
-0.00
54
223
80
529
1.71
3.82
1.9
2.0
2.74
2.94
mg/l
0.53
69
451
65
405
1.78
3.82
1.3
1.2
5.00
13.25
u/ml
1.31
28
163
41
222
1.99
3.70
6.0
9.8
5.08
5.24
kpa
0.63
41
215
41
222
1.99
3.70
6.0
9.8
11.60
12.49
kpa
0.72
41
216
15
51
3.05
3.63
1.1
1.2
491.73
462.80
mg/l
0.20
15
46
11
26
4.36
3.54
1.0
2.0
1.76
1.56
mmol/l
0.49
11
26
127
959
1.58
3.54
3.7
4.2
36.12
36.02
g/l
0.08
119
902
171
1384
1.59
3.53
9.3
9.6
3.76
3.94
e9/l
0.57
152
1207
216
1854
1.68
3.47
8.7
7.2
74.89
77.44
u/l
0.71
209
1745
17
64
2.76
3.46
1.8
1.5
—
0.07
—
0
10
12
32
3.87
3.43
1.2
1.6
—
—
—
0
0
40
225
1.90
3.24
6.1
9.7
1.53
1.59
mmol/l
0.06
32
189
10
25
4.11
3.11
1.0
1.0
—
—
—
0
0
9
21
4.39
3.02
1.3
1.8
—
—
—
0
0
51
317
1.74
3.00
1.7
1.9
—
—
—
0
0
68
457
1.64
3.00
2.0
1.6
429.82
452.28
pmol/l
0.34
62
368
5
5
10.14
2.99
1.6
1.0
—
—
—
0
0
128
996
1.52
2.98
3.1
2.6
108.35
108.15
ug/l
0.01
116
916
107
804
1.53
2.92
3.3
2.8
—
—
—
0
0
15
58
2.67
2.92
4.9
2.7
—
—
—
0
0
9
22
4.19
2.90
1.3
1.8
—
—
—
0
0
75
523
1.59
2.84
1.3
1.2
1.19
1.47
u/ml
0.15
33
143
86
623
1.54
2.75
2.7
2.8
0.22
0.45
e6/l
1.15
71
459
12
40
3.09
2.73
2.1
2.0
136.08
131.81
g/l
0.30
12
26
12
41
3.01
2.65
1.8
2.7
7.90
7.97
kpa
0.06
12
41
9
25
3.68
2.59
1.3
1.7
—
—
—
0
0
12
44
2.80
2.58
1.0
1.1
3.61
3.95
mmol/l
0.69
12
38
6
11
5.54
2.55
1.0
1.4
1.55
1.73
mmol/l
—
6
11
60
407
1.60
2.53
1.5
1.4
—
—
—
0
0
57
385
1.60
2.45
1.7
1.6
1291.09
1230.84
nmol/l
0.23
46
283
72
514
1.54
2.43
1.8
1.6
1.44
0.99
mg/l
0.69
57
406
137
1116
1.44
2.38
7.2
6.0
29.16
28.35
%
0.39
128
1043
5
8
6.34
2.38
1.4
1.5
—
—
—
0
0
136
1109
1.43
2.34
6.8
5.8
55.95
57.06
%
0.58
128
1034
266
2492
2.01
2.32
17.2
14.1
3.98
3.96
mmol/l
0.60
260
2420
172
1466
1.44
2.30
2.7
2.9
—
—
—
0
0
61
425
1.55
2.29
1.3
1.2
21.19
40.25
iu/ml
1.36
23
140
17
80
2.20
2.23
2.2
1.5
—
—
—
0
0
5
9
5.63
2.22
1.4
1.7
—
—
—
0
0
5
9
5.63
2.22
1.4
1.4
—
—
—
0
0
265
2487
1.93
2.18
17.4
14.0
139.59
139.84
mmol/l
0.83
259
2419
36
224
1.69
2.12
1.5
1.8
—
—
—
0
0
146
1226
1.39
2.03
6.7
6.3
9.30
10.65
umol/l
1.73
139
1167
36
227
1.67
2.03
1.6
1.8
—
—
—
0
0
10
38
2.69
2.02
1.2
1.4
—
—
—
0
0
6
16
3.81
1.94
1.5
1.1
—
—
—
0
0
6
16
3.81
1.94
1.5
1.1
—
—
—
0
0
13
58
2.30
1.94
2.0
1.4
—
—
—
0
0
15
72
2.14
1.90
1.5
1.3
328.30
286.86
ug/g
—
10
34
74
560
1.43
1.85
2.1
2.4
327.17
9668.13
umol/l
3.68
64
500
127
1056
1.37
1.82
2.7
2.3
—
—
—
0
0
24
141
1.77
1.74
1.3
1.7
—
—
—
0
0
5
13
3.89
1.72
1.0
1.0
—
—
—
0
0
11
49
2.29
1.65
1.8
2.8
24.79
25.60
mmol/l
0.40
11
49
110
905
1.35
1.65
1.9
1.9
98.73
97.58
pmol/l
0.07
59
432
40
274
1.53
1.63
5.2
6.5
105.05
104.15
mmol/l
0.49
40
274
253
2377
1.57
1.63
16.8
12.2
19.00
21.39
mg/l
0.58
224
1817
24
145
1.72
1.60
1.9
2.7
91.06
172.58
ng/l
1.87
24
133
62
473
1.40
1.47
4.3
3.6
1.02
1.02
kg/l
0.16
11
53
97
799
1.32
1.41
2.2
3.3
2.35
2.36
mmol/l
0.69
90
706
40
284
1.48
1.39
2.3
1.9
22.82
22.95
%
0.02
33
252
26
169
1.59
1.34
1.3
1.2
205.16
155.16
iu/ml
—
8
79
8
34
2.39
1.30
2.4
4.0
55.00
56.94
%
—
8
34
66
520
1.35
1.29
1.5
1.5
21.45
21.96
nmol/l
0.10
59
436
30
206
1.51
1.24
2.6
2.6
68.08
65.52
ml/min/173m2
0.29
12
84
5
19
2.66
1.22
1.2
1.9
—
—
—
0
0
247
2339
1.42
1.21
14.3
11.9
80.66
81.15
ml/min/173m2
0.15
220
1908
8
38
2.14
1.19
3.0
1.6
—
—
—
0
0
6
26
2.33
1.19
2.5
2.2
3.08
3.52
nmol/l
—
6
26
52
403
1.36
1.13
4.1
3.5
64.60
199.38
ng/l
0.97
40
303
20
130
1.58
1.06
1.5
1.7
—
—
—
0
0
11
60
1.87
1.04
1.2
1.2
73.60
205.46
miu/ml
—
5
29
275
2678
1.77
0.97
24.3
18.5
40.35
40.20
%
0.19
255
2532
37
279
1.37
0.96
7.1
6.1
—
—
—
0
0
16
243
0.64
0.95
2.2
1.7
—
—
—
0
0
6
27
2.25
0.94
1.3
1.5
—
—
—
0
0
275
2680
1.74
0.93
24.3
18.5
259.13
254.03
e9/l
0.70
269
2611
13
78
1.70
0.93
1.8
2.0
—
—
—
0
0
31
229
1.40
0.91
4.4
3.1
—
—
—
0
0
275
2681
1.73
0.91
24.2
18.5
4.44
4.48
e12/l
0.75
269
2611
14
87
1.64
0.89
1.4
2.0
—
—
—
0
0
245
2344
1.32
0.87
4.2
3.9
1.29
1.27
mmol/l
0.13
235
2163
254
2443
1.37
0.87
4.8
4.3
4.73
4.83
mmol/l
0.83
242
2274
11
65
1.72
0.83
1.5
1.3
—
—
—
0
0
6
32
1.89
0.82
1.3
1.8
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
103.96
—
0
24
6
33
1.84
0.79
5.7
2.6
14.22
21.20
u/ml
—
6
33
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
81
698
1.22
0.79
3.6
3.5
6.27
6.29
mg/mmol
0.00
56
421
11
69
1.62
0.69
1.1
1.1
—
—
—
0
0
14
95
1.50
0.65
1.2
1.4
30.18
32.48
iu/l
0.08
14
81
251
2429
1.28
0.65
4.7
4.3
1.53
1.54
mmol/l
0.11
240
2249
237
2281
1.23
0.63
5.6
5.2
40.56
39.25
mmol/mol
1.39
225
2128
256
2486
1.29
0.62
5.2
4.9
2.75
2.86
mmol/l
1.22
241
2306
26
203
1.31
0.58
2.0
1.8
—
—
—
0
0
8
54
1.50
0.57
1.8
1.5
202.63
358.20
mu/l
—
8
54
11
73
1.53
0.57
2.2
1.8
0.85
5.15
ug/l
0.62
11
68
14
99
1.44
0.55
1.0
1.4
—
—
—
0
0
9
60
1.52
0.55
1.1
1.1
—
—
—
0
0
29
235
1.26
0.50
2.1
2.7
4.95
8.70
umol/l
1.76
24
212
246
2391
1.21
0.49
4.7
4.3
5.99
5.87
mmol/l
0.57
230
2195
11
76
1.47
0.49
1.5
1.9
—
—
—
0
0
23
182
1.29
0.48
1.8
1.7
—
—
—
0
0
7
48
1.47
0.47
1.3
1.6
—
—
—
0
0
7
50
1.41
0.45
1.0
1.4
—
—
—
0
0
11
78
1.43
0.43
1.6
1.5
—
—
—
0
0
5
33
1.52
0.41
1.4
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
17
0.00
0.41
0.0
2.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
5
35
1.44
0.39
2.8
1.7
—
—
—
0
0
42
369
1.16
0.35
2.8
2.6
0.83
1.06
e6/l
0.39
26
196
14
109
1.30
0.34
2.6
2.2
0.73
0.67
%
0.15
14
109
7
52
1.35
0.31
1.3
1.6
—
—
—
0
0
7
53
1.33
0.31
2.3
1.3
—
—
—
0
0
7
55
1.28
0.30
1.0
1.1
—
9.82
—
0
9
15
121
1.25
0.29
1.8
1.4
—
—
—
0
0
14
112
1.26
0.29
2.6
2.3
1.50
1.28
%
0.34
14
112
10
76
1.33
0.28
2.1
1.7
—
—
—
0
0
74
687
1.10
0.27
1.8
1.6
1.45
1.37
mmol/l
0.38
56
578
6
82
0.73
0.24
1.2
1.1
—
—
—
0
0
6
82
0.73
0.24
1.2
1.1
—
—
—
0
0
49
449
1.11
0.23
1.4
1.4
—
—
—
0
0
59
547
1.10
0.23
2.7
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
27.37
—
0
11
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
0.34
—
0
6
0
11
0.00
0.21
0.0
1.1
—
74.81
—
0
11
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
12
99
1.22
0.20
1.5
1.4
—
—
—
0
0
28
251
1.13
0.19
1.5
1.8
1.41
1.37
%
0.14
28
222
11
132
0.83
0.18
1.5
1.3
—
—
—
0
0
11
91
1.22
0.18
1.6
3.6
24.91
24.64
mmol/l
0.15
11
91
24
266
0.89
0.16
3.3
2.9
0.63
0.68
ug/l
0.16
19
181
39
361
1.09
0.16
4.2
4.1
24.73
22.00
%
0.48
24
162
17
193
0.87
0.16
2.5
3.1
1.62
2.49
mmol/l
0.70
17
166
262
2597
1.11
0.14
13.1
9.9
25.61
25.34
u/l
0.11
256
2512
9
106
0.84
0.13
3.3
3.1
35.96
47.11
%
—
9
106
14
123
1.15
0.12
1.2
1.0
—
—
—
0
0
5
46
1.09
0.09
1.2
1.3
—
—
—
0
0
6
54
1.11
0.09
1.8
1.8
—
—
—
0
0
6
57
1.05
0.08
1.2
1.3
—
—
—
0
0
28
270
1.04
0.03
2.4
4.3
4.24
7.15
ug/l
0.64
19
222
162
1632
0.98
0.03
3.7
2.8
56.92
45.52
u/l
0.56
154
1527
36
353
1.02
0.01
3.3
2.7
2.24
2.74
e6/l
0.22
20
181
10
94
1.07
0.01
1.2
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
8.30
—
0
6
0
6
0.00
0.00
0.0
2.0
—
1.20
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
4.12
—
0
6
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
0.00
0.0
1.0
—
140.67
—
0
6
8
80
1.00
-0.00
1.1
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
-0.00
3.8
2.2
325.90
225.96
ug/l
—
6
59
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
109.00
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
22.16
—
0
7
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.2
—
131.20
—
0
5
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
8
0.00
-0.00
0.0
2.4
—
98.38
—
0
8
5
56
0.89
-0.00
2.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint G6_FEMLE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_FEMLE | 0.953 [0.78, 1.16] | 0.637 |
| Birth year | 0.996 [0.99, 1.0] | 0.355 |
During the follow-up period (1.1.1998 — 31.12.2019), 114 out of 1038 females with G6_FEMLE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_FEMLE | 1.514 [1.24, 1.85] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 147 out of 596 males with G6_FEMLE died.
Mortality risk
Mortality risk for people of age
years, who have G6_FEMLE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.114% | 0.246% |
| 5 | 0.603% | 1.748% |
| 10 | 1.412% | 4.45% |
| 15 | 2.804% | 8.239% |
| 20 | 5.006% | 13.697% |
Relationships between endpoints
↥Index endpoint: G6_FEMLE – Lesion of femoral nerve
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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