No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
99 |
4. Check minimum number of eventsNone |
99 |
5. Include endpointsNone |
99 |
6. Filter based on genotype QC (FinnGen only) |
99 |
Control definitions (FinnGen only)
- Control exclude
- H8_OTHEREAR
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H92
- Name in latin
- Otorrhoea
Similar endpoints
↥List of similar endpoints to Otorrhoea based on the number of shared cases.
Similar with more cases:
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 1405 | 620 | 781 |
Only index persons | 922 | 434 | 488 |
Unadjusted period prevalence (%) | |||
Whole population | 0.02 | 0.02 | 0.02 |
Only index persons | 0.02 | 0.02 | 0.02 |
Median age at first event (years) | |||
Whole population | 14.43 | 23.40 | 7.15 |
Only index persons | 38.46 | 44.95 | 32.70 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 99 | 65 | 34 |
Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 |
Median age at first event (years) | 54.85 | 51.87 | 60.56 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 89
- Matched controls
- 889
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint H8_OTORRHOEA and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_OTORRHOEA | 1.491 [1.02, 2.18] | 0.04 |
Birth year | 0.997 [0.99, 1.01] | 0.447 |
During the follow-up period (1.1.1998 — 31.12.2019), 55 out of 558 females with H8_OTORRHOEA died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_OTORRHOEA | 1.271 [0.9, 1.79] | 0.173 |
Birth year | 0.988 [0.98, 1.0] | 0.014 |
During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 707 males with H8_OTORRHOEA died.
Mortality risk
Mortality risk for people of age
years, who have H8_OTORRHOEA.N-year risk | Females | Males |
---|---|---|
1 | 0.182% | 0.25% |
5 | 1.008% | 1.486% |
10 | 2.378% | 3.85% |
15 | 4.442% | 7.101% |
20 | 8.02% | 11.758% |
Relationships between endpoints
↥Index endpoint: H8_OTORRHOEA – Otorrhoea
GWS hits: 1