Small kidney of unknown cause

N14_SMALLKIDNEY

urinary system disease: A disease involving the renal system. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — N27 Hospital discharge: ICD-9 — 589 Hospital discharge: ICD-8 — 5930 Cause of death: ICD-10 — N27 Cause of death: ICD-9 — 589 Cause of death: ICD-8 — 5930 2 out of 7 registries used, show all original rules.	82
4. Check minimum number of events None	82
5. Include endpoints None	82
6. Filter based on genotype QC (FinnGen only)	82

Control definitions (FinnGen only)

Control exclude: N14_KIDUROTH

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: N25-N29
Name in latin: Ren parvus causa ignota

NAME	N14_SMALLKIDNEY
CONTROL_EXCLUDE	N14_KIDUROTH
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	N27
HD_ICD_9	589
HD_ICD_8	5930
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	N27
COD_ICD_9	589
COD_ICD_8	5930
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Small kidney of unknown cause based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	744	400	331
Only index persons	515	303	212
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	40.66	40.97	39.57
Only index persons	33.86	35.71	31.21

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	82	46	36
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	35.74	34.24	37.65

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
69: Matched controls
689

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

N27.0

ICD-10 Finland

Small kidney, unilateral

+∞

19.7

59300

ICD-8 Finland

Other diseases of kidney and ureter, Renal dwarfism

+∞

18.6

5890A

ICD-9 Finland

Small kidney of unknown cause, Unilateral small kidney

+∞

14.0

N27.9

ICD-10 Finland

Small kidney, unspecified

+∞

7.4

N18.9

ICD-10 Finland

Chronic kidney disease, unspecified

8.2

6.1

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3048929) Epstein Barr virus Ab [Presence] in Serum

7.79

7.34

1.4

1.5

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

8.71

4.16

1.4

1.5

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

10.65

3.55

1.2

1.3

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

6.20

3.43

1.9

1.4

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

6.20

3.43

1.9

1.4

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

154

2.37

3.20

3.7

2.1

2.6

3.2

mg/l

1.10

136

(3017817) Protein [Mass] in Urine collected for unspecified duration

7.98

3.11

4.0

1.4

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

10.52

3.02

1.2

—

(3004588) Protein electrophoresis panel - Serum or Plasma

3.10

2.59

1.3

3.1

—

(21494890) Protein electrophoresis panel - 24 hour Urine

7.51

2.58

1.2

1.7

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

281

1.92

2.18

10.2

4.8

35.7

35.8

g/l

0.07

267

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

4.76

1.97

8.6

2.8

—

(3018418) pH of Serum or Plasma

196

1.84

1.78

5.7

4.3

7.4

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

291

1.73

1.62

9.8

5.8

1.2

mmol/l

0.13

263

(40760892) CBC W Ordered Manual Differential panel - Blood

142

1.86

1.61

7.1

6.5

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

2.57

1.58

1.5

1.3

1.5

g/l

—

(3026493) Urate [Moles/volume] in Serum or Plasma

186

1.77

1.55

5.9

3.0

383.9

1708.7

umol/l

0.48

162

(3022313) Gas panel - Capillary blood

2.64

1.49

3.9

4.0

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.86

1.46

1.3

4.5

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

253

1.67

1.41

2.4

2.0

85.8

93.5

pmol/l

0.50

123

(40761535) Cells panel - Urine sediment

2.13

1.41

5.5

3.7

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

522

1.77

1.38

7.6

7.7

71.1

79.6

u/l

1.83

482

(3026008) Bacteria identified in Urine by Culture

192

1.70

1.37

4.0

3.1

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

317

1.59

1.22

19.8

6.8

1.2

mmol/l

0.01

274

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

1.17

0.0

1.3

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

2.59

1.17

1.0

2.6

—

(3009343) pH of Capillary blood

2.05

1.12

6.5

3.6

—

7.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

124

1.69

1.09

1.5

1.3

—

(3052851) Hemolysis interference index of Serum or Plasma

2.35

1.05

1.4

2.5

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

119

1.66

0.99

1.8

386.6

474.5

pmol/l

0.80

107

(3019832) Treponema pallidum Ab [Presence] in Serum

1.86

0.95

1.9

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

245

1.50

0.95

6.9

3.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.83

0.91

3.4

3.2

—

(3013707) Erythrocyte sedimentation rate by Westergren method

504

1.52

0.90

4.8

3.9

11.6

10.8

mm/h

0.21

463

(3019060) Gas panel - Arterial blood

1.90

0.89

3.0

5.2

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.01

0.86

5.3

7.9

—

(3002179) Metamyelocytes/100 leukocytes in Blood

1.74

0.81

2.4

5.5

—

0.4

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.80

0.0

1.2

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.80

0.0

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.80

0.0

1.2

—

(40768443) Skin Pathology biopsy report

0.00

0.80

0.0

1.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.65

0.77

8.2

10.0

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.82

0.73

4.9

6.5

26.3

24.3

mmol/l

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

148

1.46

0.68

1.2

0.5

1.6

u/ml

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

684

1.61

0.68

18.3

14.4

19.1

24.3

mg/l

0.90

522

(3000494) Fungus identified in Specimen by Culture

1.56

0.61

1.4

1.5

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.59

0.0

1.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.54

0.58

2.4

1.5

—

(3019225) pH of Specimen

1.59

0.57

18.3

4.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

100

1.48

0.56

2.5

1.6

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

209

1.36

0.56

3.2

2.8

24.2

32.6

u/l

3.03

192

(3003694) ABO and Rh group [Type] in Blood

187

0.70

0.53

1.6

1.4

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

601

1.39

0.53

7.9

5.8

39.1

39.8

mmol/mol

0.20

560

(1761868) Lipid panel - Serum or Plasma

240

0.73

0.52

2.9

2.8

—

(42870588) Differential panel, method unspecified - Blood

221

1.33

0.52

5.9

5.4

—

(3041096) Erythrocytes [Presence] in Urine by Automated

185

0.71

0.50

6.1

3.3

—

(3002256) Pathology report gross observation

1.48

0.50

1.3

1.2

—

(3000991) Gas panel - Venous blood

1.47

0.44

12.9

6.1

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

265

0.77

0.43

3.3

3.8

24.1

33.8

ng/l

0.47

184

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.7

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.41

0.0

1.5

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.3

—

(3044640) Blood type and Crossmatch panel - Blood

218

1.28

0.41

2.3

2.2

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

1.8

—

37.6

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.41

0.0

1.6

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.41

0.0

1.6

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.40

0.0

2.4

—

54.7

—

(3044889) 12 lead EKG panel

475

0.80

0.40

4.3

3.8

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

642

1.35

0.39

5.4

4.2

4.5

4.7

mmol/l

0.74

594

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.39

0.0

1.5

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

698

1.42

0.38

21.4

16.5

98.0

77.6

umol/l

2.62

698

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

0.60

0.37

2.2

2.0

1.6

1.5

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.43

0.36

2.5

3.5

4.3

4.4

pmol/l

—

(3002385) Erythrocyte distribution width [Ratio]

572

1.26

0.34

21.3

17.4

13.7

0.04

563

(3013512) EKG study

185

1.26

0.34

4.1

3.7

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

157

1.27

0.33

1.8

0.8

0.9

mg/l

0.22

124

(36660697) Celiac disease serology panel - Serum

1.41

0.32

1.3

1.1

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

159

1.25

0.30

2.5

2.1

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

113

1.29

0.29

2.6

2.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.30

0.29

1.3

1.6

—

(3012544) pH of Venous blood

1.26

0.28

17.8

4.0

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

170

1.23

0.28

6.9

3.9

—

(40768797) Stomach Pathology biopsy report

1.32

0.28

1.3

1.2

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

640

1.26

0.28

5.3

4.2

1.4

1.5

mmol/l

0.32

585

(3007164) IgA [Mass/volume] in Serum or Plasma

142

1.25

0.27

1.2

1.5

1.7

2.2

g/l

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

107

1.26

0.23

1.6

2.0

31.1

29.1

0.37

102

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.30

0.23

8.2

3.7

116.6

129.8

g/l

—

(40758558) Short blood count panel - Blood

183

1.20

0.23

6.4

7.6

—

(3032080) INR in Blood by Coagulation assay

258

0.85

0.22

16.7

7.7

1.3

1.2

inr

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.21

0.0

2.6

—

2.3

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

312

1.15

0.20

5.0

3.7

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.27

0.20

1.9

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

152

0.83

0.18

5.8

4.0

16.3

22.0

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.25

0.18

1.9

2.0

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

130

1.19

0.17

3.3

1.9

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.77

0.16

2.0

1.9

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.74

0.16

3.0

2.1

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

200

0.87

0.14

2.3

2.1

113.6

347.4

u/l

1.30

189

(3042936) Bacteria identified in Isolate by Culture

1.20

0.14

1.4

1.8

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

631

1.15

0.13

18.2

12.9

70.4

81.8

ml/min/173m2

2.56

513

(3029937) Albumin [Presence] in Urine by Test strip

182

1.13

0.12

9.4

4.3

0.0

estimate

—

(3035350) Ketones [Presence] in Urine by Test strip

339

0.91

0.11

7.2

3.9

0.0

estimate

—

(36304419) Bacteria [Presence] in Urine

203

1.11

0.11

4.0

3.0

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

634

1.12

0.10

5.0

4.4

5.9

mmol/l

0.04

583

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.15

0.10

3.0

1.3

—

(3021601) Nitrite [Presence] in Urine by Test strip

337

0.92

0.09

8.4

5.3

0.0

estimate

—

(4010399)

1.12

0.09

1.0

1.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.82

0.08

2.5

1.9

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.06

0.07

1.4

1.6

—

(3018095) Leukocytes [#/volume] in Urine

258

1.07

0.05

8.4

3.6

36.8

83.9

e6/l

0.73

179

(40768804) Tissue Pathology biopsy report

268

1.07

0.05

1.9

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

110

1.11

0.05

1.8

1.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

458

1.06

0.05

4.3

3.2

—

(3009261) Glucose [Presence] in Urine by Test strip

341

0.95

0.04

7.0

3.9

0.5

0.0

estimate

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

601

1.06

0.03

6.1

4.9

1.7

1.9

mu/l

0.63

545

(40761511) CBC panel - Blood by Automated count

698

0.93

0.03

19.3

12.8

—

(3021589) Normoblasts [#/volume] in Blood

304

1.03

0.00

11.2

9.5

0.0

e9/l

0.00

249

(3023368) Bacteria identified in Blood by Culture

187

1.02

0.00

3.9

4.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

465

1.03

0.00

8.2

4.2

—

(3009542) Hematocrit [Volume Fraction] of Blood

605

1.03

0.00

18.9

15.0

39.6

40.2

0.21

465

(3015736) pH of Urine

266

1.02

0.00

7.3

3.9

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

0.00

0.0

8.1

—

14.1

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

3.6

—

(21494755) Public health laboratory ask at order entry panel

0.84

0.00

1.0

1.3

—

(3044941) Cell count panel - Synovial fluid

0.00

0.0

1.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

260

1.00

0.00

7.4

4.0

—

(3035880) pH of Pleural fluid

0.00

0.0

1.2

—

(3021788) Differential panel - Synovial fluid

0.00

0.0

1.7

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

0.0

1.0

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.5

—

(40768800) Prostate Pathology biopsy report

0.00

0.0

1.1

—

(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.3

—

14.3

—

(3034988) Calcium [Moles/volume] in Capillary blood

0.00

0.0

1.2

—

1.2

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.2

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.0

1.4

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.0

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.4

—

116.4

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.0

1.0

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

0.0

1.0

—

(3000492) Spirometry study

0.90

0.00

1.2

1.5

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

2.3

—

106.4

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

0.9

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.89

0.00

1.7

1.5

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.2

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

7.3

—

0.6

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

2.0

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.1

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

2.3

—

4.0

—

(3006270) Folate [Moles/volume] in Blood

0.00

0.0

1.4

—

484.8

—

(3020491) Glucose [Moles/volume] in Blood

0.00

0.0

2.6

—

6.0

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

0.0

1.3

—

9.2

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.7

—

(4281824)

0.00

0.0

1.0

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

2.0

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

2.0

—

(3037522) Nuclear Ab [Titer] in Serum

1.01

0.00

1.3

—

473.3

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3022145) Colonoscopy Study observation

1.01

0.00

1.6

1.3

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.1

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.0

2.0

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

2.3

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.0

2.4

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

2.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.0

1.0

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

0.89

0.00

2.1

2.4

25.3

29.7

u/l

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

2.0

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

0.0

1.3

—

227.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint N14_SMALLKIDNEY and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_SMALLKIDNEY.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: N14_SMALLKIDNEY – Small kidney of unknown cause

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Small kidney of unknown cause

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints