glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
235 |
4. Check minimum number of eventsNone |
235 |
5. Include endpointsNone |
235 |
6. Filter based on genotype QC (FinnGen only) |
227 |
Control definitions (FinnGen only)
- Control exclude
- H7_GLAUCOMA
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H40
- Name in latin
- Glaucoma [secundarium] posttraumaticum
Similar endpoints
↥List of similar endpoints to
Glaucoma secondary to eye trauma
based on the number of shared cases.
Similar with more cases:
- Glaucoma
- Diseases of the eye and adnexa
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2393 | 862 | 1511 |
| Only index persons | 2107 | 772 | 1335 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.02 | 0.04 |
| Only index persons | 0.04 | 0.03 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 61.99 | 69.56 | 57.65 |
| Only index persons | 60.89 | 68.48 | 56.50 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 227 | 87 | 140 |
| Unadjusted period prevalence (%) | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | 61.43 | 58.92 | 63.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 235
- Matched controls
- 2350
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
114
Kela drug reimbursment
Glaucoma
227.1
307.7
182
35
S01ED51
ATC
timolol, combinations; ophthalmic
180.8
307.7
177
39
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
16384.0
299.6
220
*
S01EE01
ATC
latanoprost; ophthalmic
121.3
248.8
133
25
S01ED01
ATC
timolol; ophthalmic
128.5
224.7
117
18
S01EC01
ATC
acetazolamide; systemic
107.7
151.1
79
11
XCK00
NOMESCO Finland
Perimetry
36.7
127.4
87
37
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
333.4
103.8
98
5
S01EA05
ATC
brimonidine; ophthalmic
368.3
96.5
91
*
S01EC04
ATC
brinzolamide; ophthalmic
217.9
95.3
93
7
S01EE05
ATC
tafluprost; ophthalmic
60.1
84.0
48
10
H40.0
ICD-10 Finland
Glaucoma suspect
175.1
81.0
81
7
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
+∞
78.7
71
*
S01EX03, ,
ATC
155.2
65.9
67
6
WX140
NOMESCO Finland
Parabulbar anesthesy
15.2
54.0
52
43
Z96.1
ICD-10 Finland
Presence of intraocular lens
7.8
52.5
102
210
S01EC03
ATC
dorzolamide; ophthalmic
299.8
49.0
48
*
XCH00
NOMESCO Finland
Eye pressure measurement
13.7
44.5
45
40
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.9
43.8
74
129
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
+∞
43.1
40
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
6.3
41.2
163
622
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
+∞
40.8
38
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
+∞
40.8
38
*
S01EE04
ATC
travoprost; ophthalmic
127.2
40.2
42
*
S01EE03
ATC
bimatoprost; ophthalmic
82.2
37.3
41
6
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
7.4
34.1
58
100
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
11.1
33.3
38
40
XCK10
NOMESCO Finland
Photography of fundus of eye
6.3
31.4
64
132
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
4.5
28.4
152
675
S01EC54
ATC
brinzolamide, combinations; ophthalmic
303.9
27.3
27
*
H40.9
ICD-10 Finland
Glaucoma, unspecified
290.9
26.2
26
*
CHD00
NOMESCO Finland
Laser trabeculoplasty
290.9
26.2
26
*
S01ED02
ATC
betaxolol; ophthalmic
151.8
26.2
27
*
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
+∞
25.5
24
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.6
25.0
78
229
S01BA01
ATC
dexamethasone; ophthalmic
9.7
24.2
30
35
H20.1
ICD-10 Finland
Chronic iridocyclitis
72.7
23.3
26
*
3656E
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POSTTRAUMATICUM]
+∞
23.3
22
*
S01EB01
ATC
pilocarpine; ophthalmic
88.8
22.1
24
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.8
21.9
59
153
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
7.2
20.7
33
52
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
+∞
20.1
19
*
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
24.3
20.0
28
13
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
+∞
19.0
18
*
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
+∞
19.0
18
*
CHC05
NOMESCO Finland
Iridotomy
108.8
18.9
20
*
H26.1
ICD-10 Finland
Traumatic cataract
48.3
18.6
22
5
S01BA07
ATC
fluorometholone; ophthalmic
25.2
18.2
25
11
CHD99
NOMESCO Finland
Other filtering operation
+∞
17.9
17
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.7
17.7
47
119
S01EA03
ATC
apraclonidine; ophthalmic
45.9
17.6
21
5
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.2
17.3
124
608
H26.4
ICD-10 Finland
After-cataract
4.3
17.0
51
142
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
18.1
17.0
26
16
37520
ICD-8 Finland
Glaucoma, Secondary
+∞
16.9
16
*
H40
ICD-10 Finland
Glaucoma
182.4
16.7
17
*
ZXA05
NOMESCO Finland
Left side
3.2
16.6
95
406
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
32.7
16.4
21
7
S01EA02
ATC
dipivefrine; ophthalmic
+∞
15.8
15
*
XCH05
NOMESCO Finland
Eye pressure longterm registration
170.9
15.7
16
*
ZXD20
NOMESCO Finland
Day surgery
4.1
15.6
50
146
S01BC03
ATC
diclofenac; ophthalmic
18.1
15.1
23
14
H27.0
ICD-10 Finland
Aphakia
56.9
14.0
16
*
H40.8
ICD-10 Finland
Other glaucoma
+∞
13.7
13
*
S01BA04
ATC
prednisolone; ophthalmic
11.4
12.0
22
21
H04.10
ICD-10 Finland
Dry eye syndrome
3.8
11.9
41
125
CS494
NOMESCO Finland
Other visual field testing
20.2
11.8
17
9
CHD35
NOMESCO Finland
Laser goniopuncture
+∞
11.5
11
*
H18.1
ICD-10 Finland
Bullous keratopathy
125.9
11.5
12
*
S05.6
ICD-10 Finland
Penetrating wound of eyeball without foreign body
+∞
10.5
10
*
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
19.9
10.4
15
8
H33.0
ICD-10 Finland
Retinal detachment with retinal break
5.7
10.3
20
38
H16.0
ICD-10 Finland
Corneal ulcer
4.7
10.1
24
55
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
8.4
9.9
21
27
H40.11
ICD-10 Finland
Low pressure glaucoma
57.4
9.7
11
*
ZXC20
NOMESCO Finland
Use of chemical agents
9.7
9.7
19
21
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
11.4
9.5
17
16
CFW99
NOMESCO Finland
Other operation on conjunctiva
+∞
9.4
9
*
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
+∞
9.4
9
*
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
+∞
9.4
9
*
H34.8
ICD-10 Finland
Other retinal vascular occlusions
9.6
9.2
18
20
WX142
NOMESCO Finland
Sub-tenon anesthesy
38.3
9.1
11
*
WX002
NOMESCO Finland
Sedation and analgesia
2.7
9.1
60
267
H21.0
ICD-10 Finland
Hyphaema
93.3
8.5
9
*
W44
ICD-10 Finland
Foreign body entering into or through eye or natural orifice
10.0
8.4
16
17
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
+∞
8.4
8
*
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
8.4
8
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
+∞
8.4
8
*
H44.5
ICD-10 Finland
Degenerated conditions of globe
+∞
8.4
8
*
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
+∞
8.4
8
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.3
8.2
34
116
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
34.7
8.1
10
*
ZXA00
NOMESCO Finland
Right side
2.3
7.9
79
423
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
46.6
7.8
9
*
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
46.6
7.8
9
*
H16.9
ICD-10 Finland
Keratitis, unspecified
12.4
7.7
13
11
H25.1
ICD-10 Finland
Senile nuclear cataract
2.2
7.5
91
525
H3603, E103,
ICD-10 Finland
82.6
7.5
8
*
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
82.6
7.5
8
*
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
82.6
7.5
8
*
3708
FHL
Trabeculectomy or equivalent
+∞
7.3
7
*
TCG10
NOMESCO Finland
Removal of sutures from cornea
+∞
7.3
7
*
87001
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Non complicata (sive NUD)
+∞
7.3
7
*
H40.1
ICD-10 Finland
Primary open-angle glaucoma
+∞
7.3
7
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
7.3
7
*
3662A
ICD-9 Finland
Cataract, Traumatic cataract
+∞
7.3
7
*
3650A
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AVOKULMA)]
+∞
7.3
7
*
Z3231
NOMESCO Finland
Registered nurse
2.2
7.0
79
442
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.7
6.9
22
63
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
9.8
6.9
13
14
S01FA01
ATC
atropine; ophthalmic
17.3
6.8
10
6
H26.2
ICD-10 Finland
Complicated cataract
17.3
6.8
10
6
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
17.3
6.8
10
6
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
23.3
6.7
9
*
W22
ICD-10 Finland
Striking against or struck by other object(s)
3.6
6.6
22
65
87011
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Complicata
71.7
6.5
7
*
CKD60
NOMESCO Finland
Anterior vitrectomy
14.8
6.5
10
7
CGF10
NOMESCO Finland
Suture of laceration of cornea
+∞
6.3
6
*
87091
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Sequelae
+∞
6.3
6
*
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
+∞
6.3
6
*
3711
FHL
Cyclodiateria or cryocoagulation
+∞
6.3
6
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
3.8
6.2
19
53
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
5
0
+∞
5.22
1.8
0.0
107.60
—
ng/l
—
5
0
126
922
1.79
4.60
9.3
6.9
1.21
1.21
mmol/l
0.26
110
782
51
295
1.93
3.89
2.5
3.4
0.86
0.82
mmol/l
1.64
45
277
87
596
1.73
3.82
3.2
2.6
53.12
63.17
u/l
0.66
78
553
212
1875
2.34
3.80
23.4
18.8
139.46
139.70
mmol/l
0.72
207
1823
205
1796
2.11
3.66
19.9
16.3
25.71
25.72
mg/l
0.00
169
1467
212
1882
2.29
3.64
23.9
18.9
3.99
4.00
mmol/l
0.21
206
1830
125
971
1.61
3.24
7.3
6.6
12.51
11.61
umol/l
0.22
115
923
110
840
1.58
2.99
6.4
5.9
1.21
1.21
mmol/l
0.06
103
764
169
1431
1.64
2.93
9.5
7.7
84.95
79.99
u/l
0.57
156
1334
216
1965
2.23
2.93
28.7
23.5
240.25
240.39
e9/l
0.01
210
1915
216
1965
2.23
2.93
28.7
23.6
39.90
39.78
%
0.09
194
1836
216
1965
2.23
2.93
28.8
23.5
4.45
4.47
e12/l
0.17
208
1907
50
317
1.73
2.81
1.8
2.0
—
—
—
0
0
59
397
1.65
2.65
1.8
1.7
950.63
1258.03
nmol/l
1.99
43
304
183
1609
1.62
2.44
4.4
4.4
1.93
2.00
mu/l
0.31
155
1434
24
126
2.01
2.41
1.7
1.5
—
—
—
0
0
7
17
4.21
2.38
1.3
1.4
—
—
—
0
0
67
481
1.55
2.28
2.6
2.1
3.20
3.26
mg/l
0.05
59
416
81
610
1.50
2.20
4.5
3.7
17.99
10.52
mg/mmol
0.38
58
406
59
415
1.56
2.19
1.5
1.9
445.85
428.08
pmol/l
0.17
47
353
119
969
1.46
2.18
30.1
15.4
1.42
1.29
inr
0.59
41
285
13
58
2.31
1.94
1.5
1.5
—
—
—
0
0
155
1352
1.43
1.82
5.1
3.9
15.53
13.24
mm/h
0.68
144
1233
86
677
1.43
1.81
2.4
2.2
78.61
77.36
nmol/l
0.14
77
597
14
68
2.13
1.74
1.4
1.7
—
—
—
0
0
15
75
2.07
1.74
1.5
1.9
—
—
—
0
0
77
603
1.41
1.65
3.8
3.3
2.34
2.34
mmol/l
0.06
63
533
5
14
3.62
1.62
5.0
2.6
—
—
—
0
0
22
130
1.76
1.59
1.3
1.6
—
—
—
0
0
51
372
1.47
1.59
4.7
3.7
113.94
209.59
ng/l
0.52
40
309
24
146
1.72
1.58
5.7
7.1
24.87
24.33
mmol/l
0.21
24
139
18
100
1.87
1.58
4.5
3.0
0.75
0.69
%
0.46
18
100
204
1896
1.58
1.56
13.7
10.6
28.41
25.16
u/l
0.79
198
1817
190
1743
1.47
1.52
5.6
4.8
6.32
6.10
mmol/l
1.12
165
1588
33
224
1.55
1.44
1.8
1.9
—
—
—
0
0
93
768
1.35
1.41
2.0
2.0
95.28
93.00
pmol/l
0.18
47
419
18
105
1.77
1.37
4.5
3.0
0.96
1.07
%
0.38
18
105
33
228
1.52
1.33
1.8
2.0
—
—
—
0
0
94
784
1.33
1.32
4.5
4.2
92.71
43.43
ng/l
0.47
72
582
120
1041
1.31
1.26
10.6
9.5
4.26
4.29
e9/l
0.06
112
905
8
36
2.26
1.25
1.8
1.4
—
—
—
0
0
102
870
1.30
1.20
2.8
2.8
—
—
—
0
0
10
50
2.04
1.18
1.2
1.2
—
—
—
0
0
181
1673
1.36
1.16
8.2
6.2
42.73
41.00
mmol/mol
1.38
163
1553
109
942
1.29
1.15
2.9
2.6
—
—
—
0
0
104
894
1.29
1.14
5.6
5.2
2.47
2.73
ug/l
0.22
88
792
38
280
1.43
1.13
3.4
2.7
20.55
22.49
%
0.40
30
244
62
497
1.34
1.12
3.2
2.8
16974.13
7312.82
umol/l
0.37
47
426
26
178
1.52
1.11
2.9
2.7
4.40
5.93
ug/l
0.60
20
157
95
810
1.29
1.10
7.7
4.8
34.40
35.02
g/l
0.51
90
765
87
735
1.29
1.08
3.4
2.7
133.67
159.07
ug/l
0.66
78
678
34
249
1.43
1.05
4.3
6.8
1.41
1.23
mmol/l
0.09
28
197
7
34
2.09
1.03
5.7
3.5
109.00
105.26
mmol/l
—
7
34
179
1665
1.32
1.00
4.6
4.1
1.31
1.31
mmol/l
0.05
156
1525
74
619
1.29
0.98
3.3
3.4
1680.87
1803.36
ng/l
0.11
66
537
14
85
1.69
0.96
1.1
1.2
69.59
293.75
u/ml
1.91
14
78
49
388
1.33
0.96
1.3
1.7
2.19
1.34
mg/l
0.50
39
304
9
51
1.79
0.95
1.3
1.1
0.25
0.23
g/l
—
9
51
183
1718
1.29
0.88
5.1
4.6
1.34
1.42
mmol/l
1.64
163
1578
15
96
1.60
0.86
1.7
2.1
0.80
1.49
ug/l
—
10
89
8
45
1.80
0.85
3.9
1.8
—
—
—
0
0
184
1731
1.29
0.85
5.1
4.6
4.44
4.52
mmol/l
0.40
166
1601
82
706
1.25
0.85
5.1
4.6
22.78
21.19
%
0.38
39
370
6
32
1.90
0.82
1.0
1.2
—
—
—
0
0
139
1270
1.23
0.82
3.8
3.7
14.83
14.88
pmol/l
0.08
119
1127
188
1777
1.29
0.81
5.9
5.1
2.62
2.66
mmol/l
0.20
169
1630
6
33
1.84
0.79
1.3
1.4
—
—
—
0
0
36
282
1.33
0.77
1.1
1.2
29.31
36.16
iu/ml
—
10
89
9
53
1.73
0.76
1.3
1.2
1.16
1.13
g/l
—
9
53
34
265
1.33
0.75
6.9
6.4
104.21
104.07
mmol/l
0.06
34
265
5
24
2.11
0.75
1.8
1.3
—
—
—
0
0
53
440
1.26
0.74
2.5
2.6
—
—
—
0
0
7
38
1.87
0.74
1.3
1.6
—
—
—
0
0
83
726
1.22
0.73
5.3
4.1
—
—
—
0
0
9
57
1.60
0.72
1.3
1.6
—
—
—
0
0
5
26
1.94
0.71
3.8
5.1
—
—
—
0
0
101
905
1.20
0.69
4.8
3.9
0.00
0.00
estimate
-0.00
23
190
7
42
1.69
0.69
1.0
1.5
—
—
—
0
0
7
42
1.69
0.69
1.0
1.5
—
—
—
0
0
7
42
1.69
0.69
1.0
1.1
—
—
—
0
0
20
146
1.40
0.66
2.7
3.7
1.85
1.85
mmol/l
0.00
13
105
10
62
1.64
0.66
2.5
2.4
95.00
72.82
ug/min
—
5
38
7
44
1.61
0.65
1.0
1.4
—
3.29
—
0
11
0
22
0.00
0.59
0.0
2.1
—
4.60
—
0
5
8
53
1.53
0.59
1.3
1.6
—
—
—
0
0
6
37
1.64
0.56
1.0
1.8
—
—
—
0
0
6
37
1.64
0.56
1.0
1.8
—
—
—
0
0
30
241
1.28
0.56
6.5
8.0
—
—
—
0
0
99
900
1.17
0.55
6.7
5.3
0.00
0.00
estimate
-0.00
23
175
32
260
1.27
0.55
1.1
1.3
33.83
16.60
u/ml
0.29
12
95
6
38
1.59
0.54
1.0
1.4
—
—
—
0
0
12
85
1.43
0.48
3.6
2.1
39.92
37.51
u/l
0.20
12
76
7
51
1.38
0.44
1.9
1.2
0.72
0.83
nmol/l
—
7
42
7
51
1.38
0.44
1.3
1.6
—
—
—
0
0
58
514
1.17
0.44
5.3
3.9
0.00
0.00
estimate
-0.00
23
162
99
914
1.14
0.43
4.9
3.9
0.00
0.00
estimate
-0.00
23
164
37
315
1.21
0.43
1.9
1.9
30.34
29.36
s
0.55
37
307
159
1516
1.15
0.43
23.3
19.3
15.37
15.35
%
0.02
153
1500
29
241
1.23
0.42
4.6
4.6
28.38
31.98
%
0.73
21
168
37
316
1.20
0.42
3.4
3.0
2.83
1.03
e6/l
0.80
24
200
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
8.86
—
0
16
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
15
116
1.31
0.38
1.5
1.7
—
—
—
0
0
177
1707
1.15
0.38
19.2
14.8
72.26
76.91
ml/min/173m2
1.59
145
1397
10
73
1.39
0.35
1.8
2.6
—
—
—
0
0
119
1125
1.12
0.34
3.6
3.2
77.42
52.29
u/l
0.77
106
1050
28
240
1.19
0.32
1.8
1.4
—
—
—
0
0
55
499
1.13
0.31
3.3
3.0
0.79
0.79
ug/l
0.00
37
325
7
56
1.26
0.29
4.9
4.4
—
3.55
—
0
7
8
62
1.30
0.28
1.0
1.3
—
—
—
0
0
59
544
1.11
0.26
3.9
3.4
0.79
0.58
e6/l
0.16
49
421
24
208
1.17
0.25
3.8
3.7
—
—
—
0
0
39
352
1.13
0.24
1.3
1.2
0.54
1.69
u/ml
—
9
100
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
5
39
1.29
0.23
1.0
1.2
—
—
—
0
0
5
40
1.26
0.22
1.4
1.4
—
—
—
0
0
40
364
1.12
0.22
3.1
3.0
2.48
2.45
mmol/l
0.58
32
321
0
12
0.00
0.21
0.0
5.0
—
81.75
—
0
12
0
12
0.00
0.21
0.0
1.8
—
3.29
—
0
7
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
9
112
0.80
0.20
2.6
2.1
—
—
—
0
0
6
52
1.16
0.19
1.7
2.3
100.00
84.75
%
—
6
52
8
73
1.10
0.16
1.1
2.4
4.34
3.04
g/l
—
8
65
8
73
1.10
0.16
1.1
2.3
10.86
10.06
g/l
—
8
64
7
90
0.77
0.14
1.0
1.3
—
—
—
0
0
17
152
1.13
0.12
2.4
3.3
65.20
60.87
ml/min/173m2
—
5
67
10
85
1.18
0.12
1.0
1.0
—
—
—
0
0
10
116
0.86
0.12
1.6
1.6
—
—
—
0
0
15
166
0.90
0.10
3.3
2.8
65.45
66.43
g/l
0.28
15
148
6
54
1.11
0.09
1.2
1.5
—
—
—
0
0
5
62
0.80
0.08
1.0
1.2
—
—
—
0
0
5
63
0.79
0.08
1.0
1.2
—
—
—
0
0
9
101
0.89
0.06
2.4
2.0
—
—
—
0
0
44
451
0.97
0.03
1.7
1.6
1.31
1.36
mmol/l
0.21
36
373
46
452
1.02
0.01
1.7
1.7
18.02
20.20
nmol/l
0.45
38
381
71
717
0.99
0.01
4.2
3.4
—
—
—
0
0
30
301
1.00
0.00
3.6
3.2
1.31
1.88
e6/l
0.29
17
188
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.1
—
13.24
—
0
7
8
80
1.00
-0.00
1.1
2.3
4.36
3.63
g/l
—
8
72
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
7
0.00
-0.00
0.0
4.9
—
103.43
—
0
7
8
80
1.00
-0.00
1.1
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.92
-0.00
1.4
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
-0.00
0.0
1.0
—
132.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
75.86
—
0
8
8
80
1.00
-0.00
1.1
2.3
9.31
7.47
g/l
—
8
72
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.3
—
91.88
—
0
8
8
84
0.95
-0.00
4.3
3.1
30.50
598.83
u/ml
—
8
70
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.2
2.5
31.63
37.46
g/l
—
6
54
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
18
180
1.00
-0.00
1.4
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_GLAUCSECTRAUMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_GLAUCSECTRAUMA | 1.083 [0.92, 1.27] | 0.327 |
| Birth year | 0.994 [0.99, 1.0] | 0.134 |
During the follow-up period (1.1.1998 — 31.12.2019), 277 out of 736 females with H7_GLAUCSECTRAUMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_GLAUCSECTRAUMA | 1.166 [0.99, 1.37] | 0.061 |
| Birth year | 0.984 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 310 out of 1144 males with H7_GLAUCSECTRAUMA died.
Mortality risk
Mortality risk for people of age
years, who have H7_GLAUCSECTRAUMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.096% | 0.217% |
| 5 | 0.64% | 1.213% |
| 10 | 1.766% | 3.075% |
| 15 | 3.328% | 5.942% |
| 20 | 5.542% | 9.904% |
Relationships between endpoints
↥Index endpoint: H7_GLAUCSECTRAUMA – Glaucoma secondary to eye trauma
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data