eyelid disease: A disease involving the eyelid.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
315 |
4. Check minimum number of eventsNone |
315 |
5. Include endpointsNone |
315 |
6. Filter based on genotype QC (FinnGen only) |
315 |
Control definitions (FinnGen only)
- Control exclude
- H7_LIDLACRIMALORBIT
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H02
- Name in latin
- Xanthelasma palpebrae
Similar endpoints
↥List of similar endpoints to Xanthelasma of eyelid based on the number of shared cases.
Similar with more cases:
- Other disorders of eyelid
- Disorders of eyelid, lacrimal system and orbit
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 2377 | 1690 | 683 |
Only index persons | 2263 | 1624 | 639 |
Unadjusted period prevalence (%) | |||
Whole population | 0.04 | 0.05 | 0.02 |
Only index persons | 0.05 | 0.06 | 0.02 |
Median age at first event (years) | |||
Whole population | 53.93 | 54.29 | 52.96 |
Only index persons | 53.67 | 54.08 | 52.62 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 315 | 215 | 100 |
Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.04 |
Median age at first event (years) | 54.15 | 54.02 | 54.45 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 288
- Matched controls
- 2880
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint H7_XANTHELASMA and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
H7_XANTHELASMA | 1.022 [0.88, 1.19] | 0.785 |
Birth year | 0.991 [0.98, 1.0] | 0.051 |
During the follow-up period (1.1.1998 — 31.12.2019), 206 out of 1522 females with H7_XANTHELASMA died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
H7_XANTHELASMA | 1.057 [0.87, 1.28] | 0.572 |
Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 120 out of 633 males with H7_XANTHELASMA died.
Mortality risk
Mortality risk for people of age
years, who have H7_XANTHELASMA.N-year risk | Females | Males |
---|---|---|
1 | 0.096% | 0.197% |
5 | 0.591% | 1.24% |
10 | 1.353% | 3.169% |
15 | 2.571% | 6.058% |
20 | 4.416% | 9.757% |
Relationships between endpoints
↥Index endpoint: H7_XANTHELASMA – Xanthelasma of eyelid
GWS hits: 1