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Xanthelasma of eyelid

DOID EFO Endpoint Browser PheWeb

H7_XANTHELASMA

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H02.6
  • Cause of death: ICD-10 — H02.6

2 out of 7 registries used, show all original rules.

318

4. Check minimum number of events

None

318

5. Include endpoints

None

318

6. Filter based on genotype QC (FinnGen only)

308

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H02
Name in latin
Xanthelasma palpebrae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2377 1690 683
Only index persons 2263 1624 639
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.02
Only index persons 0.05 0.06 0.02
Median age at first event (years)
Whole population 53.93 54.29 52.96
Only index persons 53.67 54.08 52.62

-FinnGen-

Key figures

All Female Male
Number of individuals 308 208 100
Unadjusted period prevalence (%) 0.06 0.07 0.05
Median age at first event (years) 54.20 54.00 54.60

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
318
Matched controls
3180
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02.6
ICD-10 Finland
Xanthelasma of eyelid
+∞
307.7
318
*
CBB30
NOMESCO Finland
Excision of lesion of eyelid
39.7
160.5
105
39
H02.3
ICD-10 Finland
Blepharochalasis
72.6
39.2
44
7
CBB99
NOMESCO Finland
Other excision or destruction of lesion of eyelid
122.3
31.3
33
*
ZXC10
NOMESCO Finland
Use of laser
8.2
20.3
28
37
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
70.8
17.9
20
*
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
+∞
17.9
17
*
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
+∞
15.8
15
*
H02.4
ICD-10 Finland
Ptosis of eyelid
40.3
15.6
19
5
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
+∞
13.6
13
*
SPAT1153
SPAT
Removal of sutures
2.3
11.0
126
712
ZXA10
NOMESCO Finland
Bilateral
2.5
10.7
79
366
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
10.3
88
436
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
4.6
10.0
24
55
WX110
NOMESCO Finland
Infiltration anesthesia
2.3
10.0
236
1757
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.4
9.6
79
384
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
7.3
8.7
20
29
N07BA03
ATC
varenicline; oral
3.9
7.9
24
66
N02AX02
ATC
tramadol; systemic, rectal
1.9
7.7
154
1036
H04.10
ICD-10 Finland
Dry eye syndrome
3.1
7.6
34
120
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
7.6
75
390
C10AA01
ATC
simvastatin; oral
1.9
7.6
145
961
C10AA05
ATC
atorvastatin; oral
1.9
7.4
152
1028
H02.1
ICD-10 Finland
Ectropion of eyelid
+∞
7.3
7
*
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
4.0
7.1
20
52
C10AA07
ATC
rosuvastatin; oral
1.9
6.9
122
783
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.2
6.5
57
282
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
11.3
6.3
11
10
C10AX09
ATC
ezetimibe; oral
2.1
6.3
64
336
ZXC07
NOMESCO Finland
Carbon dioxide laser
+∞
6.3
6
*
J01AA02
ATC
doxycycline; systemic
2.1
6.0
259
2161

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
121
816
1.78
5.56
3.6
3.7
7.67
8.01
mg/mmol
0.03
78
521
222
1787
1.80
5.42
4.8
4.1
—
—
—
0
0
192
1515
1.67
4.72
4.9
4.2
6.82
6.69
mmol/l
0.38
175
1421
111
772
1.67
4.37
3.0
3.1
46.99
211.61
mg/l
0.81
65
507
114
808
1.64
4.13
2.9
3.0
8.12
7.24
mmol/l
1.09
98
686
141
1064
1.58
3.89
2.2
2.0
95.50
97.99
pmol/l
0.24
78
527
159
1238
1.57
3.81
13.0
12.8
1.15
1.22
inr
0.52
45
372
243
2096
1.68
3.72
8.1
7.4
83.32
77.79
u/l
0.51
236
1958
234
2013
1.61
3.47
4.9
4.2
15.09
12.50
mm/h
1.77
225
1865
59
367
1.75
3.42
1.2
1.2
—
—
—
0
0
115
852
1.55
3.33
2.8
2.3
52.06
55.82
u/l
0.98
108
791
298
2765
2.24
3.16
16.4
12.9
—
—
—
0
0
21
93
2.35
3.10
2.0
2.8
—
—
—
0
0
163
1321
1.48
2.99
7.0
5.5
2.02
2.00
e9/l
0.05
153
1177
108
808
1.51
2.92
4.2
3.7
—
—
—
0
0
287
2643
1.88
2.88
18.3
13.4
20.20
22.56
mg/l
0.75
249
2094
128
995
1.48
2.86
3.8
3.7
39.58
33.52
ng/l
0.14
92
707
236
2071
1.54
2.86
4.9
4.0
14.91
14.85
pmol/l
0.14
222
1873
46
281
1.74
2.84
1.5
1.6
—
—
—
0
0
159
1292
1.46
2.82
6.8
5.4
0.65
0.57
e9/l
2.49
146
1117
159
1294
1.46
2.79
6.8
5.5
0.04
0.04
e9/l
1.08
146
1120
17
72
2.44
2.77
1.0
1.1
—
—
—
0
0
164
1344
1.45
2.77
7.0
5.9
0.20
0.19
e9/l
0.36
152
1184
130
1024
1.46
2.68
3.6
3.3
5.50
5.80
ph
—
6
79
107
813
1.48
2.65
2.2
2.1
132.42
190.38
u/l
1.36
102
775
276
2529
1.69
2.60
7.3
5.8
41.04
39.89
mmol/mol
1.33
262
2357
5
7
7.23
2.56
1.0
1.0
—
—
—
0
0
300
2823
2.11
2.52
20.7
16.1
75.12
74.88
umol/l
0.05
300
2823
271
2481
1.62
2.45
6.0
4.8
1.84
1.93
mu/l
0.49
254
2262
160
1329
1.41
2.39
7.9
6.0
1.21
1.22
mmol/l
1.33
139
1135
38
232
1.72
2.37
1.9
1.5
—
—
—
0
0
180
1529
1.41
2.35
9.2
9.5
4.49
4.01
e9/l
1.95
165
1345
148
1219
1.40
2.29
7.0
6.0
—
—
—
0
0
199
1729
1.40
2.22
4.9
4.2
222.33
249.22
e6/l
—
6
32
283
2634
1.68
2.21
5.8
4.6
6.18
5.97
mmol/l
1.66
267
2420
105
819
1.42
2.20
3.5
2.9
—
—
—
0
0
50
345
1.53
1.94
1.5
1.3
594.29
537.22
titre
0.09
14
79
86
663
1.41
1.90
7.8
7.0
—
—
—
0
0
12
52
2.36
1.90
1.6
1.9
133.17
131.21
g/l
—
6
39
66
491
1.43
1.77
3.2
2.9
547.47
540.19
mosm/kgh2o
0.08
60
429
28
171
1.70
1.77
2.8
2.8
4.17
6.17
e9/l
0.64
22
141
305
2926
2.04
1.77
26.6
20.2
40.23
40.06
%
0.14
287
2732
131
1093
1.34
1.75
2.1
2.1
—
—
—
0
0
153
1308
1.33
1.72
4.2
3.6
0.00
0.00
estimate
-0.00
26
237
88
693
1.37
1.70
5.8
3.9
—
—
—
0
0
31
198
1.63
1.67
1.5
1.4
—
—
—
0
0
212
1906
1.34
1.65
4.2
3.8
—
—
—
0
0
112
920
1.34
1.65
3.9
3.6
46.34
70.13
e6/l
0.55
84
643
20
113
1.82
1.64
10.7
8.2
—
—
—
0
0
150
1289
1.31
1.59
4.1
3.6
0.00
0.00
estimate
0.50
28
266
43
302
1.49
1.55
1.8
1.4
—
—
—
0
0
5
15
3.37
1.53
1.2
1.9
—
—
—
0
0
15
79
1.94
1.52
3.1
4.5
—
—
—
0
0
131
1112
1.30
1.50
2.5
2.3
76.50
77.22
nmol/l
0.11
123
990
75
589
1.36
1.47
1.8
1.6
0.92
1.17
mg/l
0.73
63
471
90
727
1.33
1.46
3.9
3.4
—
—
—
0
0
149
1290
1.29
1.46
5.7
4.8
0.00
0.00
estimate
0.50
25
241
287
2729
1.53
1.45
6.3
5.1
2.96
2.82
mmol/l
1.52
272
2516
39
273
1.49
1.44
7.2
6.9
0.59
1.44
mmol/l
0.94
34
220
138
1185
1.29
1.44
10.1
8.9
0.00
0.00
e9/l
0.55
124
964
64
495
1.37
1.38
1.7
1.7
933.28
1271.88
nmol/l
2.22
50
373
15
82
1.87
1.38
1.6
1.6
—
—
—
0
0
141
1219
1.28
1.38
2.9
2.4
—
—
—
0
0
6
23
2.64
1.37
2.8
2.8
2.22
3.26
nmol/l
—
6
23
63
487
1.37
1.36
1.6
1.5
2.77
2.50
g/l
0.33
39
296
5
17
2.97
1.36
1.0
1.1
—
2.06
—
0
5
16
91
1.80
1.31
1.1
1.4
24.29
29.97
iu/l
0.33
16
76
100
832
1.29
1.31
2.8
2.2
—
—
—
0
0
12
62
1.97
1.29
1.2
1.1
—
—
—
0
0
5
18
2.80
1.29
3.8
2.7
—
—
—
0
0
66
520
1.34
1.27
2.9
2.6
5.24
4.90
e6/l
0.09
60
475
17
100
1.74
1.26
7.6
5.1
1.01
0.89
%
0.62
17
93
17
100
1.74
1.26
7.6
5.0
1.41
1.56
%
0.42
17
92
296
2848
1.57
1.23
12.7
10.4
26.06
25.63
u/l
0.17
290
2752
72
578
1.32
1.22
3.8
3.4
—
—
—
0
0
137
1198
1.25
1.17
7.0
5.1
1.21
1.22
mmol/l
1.11
126
1094
10
50
2.03
1.17
1.1
1.2
19.55
10.43
u/l
—
10
39
17
103
1.69
1.15
1.2
1.2
—
—
—
0
0
280
2673
1.40
1.14
5.6
4.6
4.85
4.77
mmol/l
0.51
266
2480
8
40
2.03
1.13
2.8
2.5
4.10
4.03
mmol/l
—
8
40
8
40
2.03
1.13
2.8
2.5
—
—
—
0
0
8
40
2.03
1.13
2.8
2.5
106.13
105.98
mmol/l
—
8
40
60
475
1.32
1.12
4.1
3.8
57.95
337.46
ng/l
2.45
43
371
271
2578
1.35
1.09
5.0
4.1
1.34
1.30
mmol/l
0.39
250
2366
74
608
1.28
1.06
2.4
2.1
3.05
3.22
mg/l
0.24
67
519
21
138
1.56
1.06
3.2
3.5
—
—
—
0
0
5
22
2.29
1.03
1.6
1.1
—
—
—
0
0
94
798
1.25
1.03
3.5
3.0
30.19
58.97
e6/l
0.94
77
596
7
35
2.02
1.00
1.1
1.1
—
—
—
0
0
7
35
2.02
1.00
1.0
1.1
—
—
—
0
0
11
61
1.83
0.99
3.8
3.4
—
—
—
0
0
69
567
1.28
0.99
4.7
3.9
1.02
1.02
kg/l
0.01
15
73
5
23
2.19
0.98
1.0
1.4
—
—
—
0
0
71
588
1.27
0.95
1.8
1.7
377.32
23124185.25
pmol/l
0.79
63
493
29
211
1.41
0.92
3.0
4.0
0.25
0.15
%
0.21
12
71
6
30
2.02
0.87
1.5
1.1
—
—
—
0
0
15
226
0.65
0.86
4.9
3.2
—
—
—
0
0
8
44
1.84
0.86
1.5
1.7
—
—
—
0
0
12
73
1.67
0.83
8.6
6.3
1.75
1.26
mmol/l
1.11
12
66
19
131
1.48
0.80
1.4
1.8
—
—
—
0
0
6
33
1.83
0.79
4.5
1.8
90.57
90.11
%
—
6
33
35
271
1.33
0.78
3.9
3.8
—
—
—
0
0
0
27
0.00
0.78
0.0
1.1
—
—
—
0
0
0
27
0.00
0.78
0.0
1.1
—
—
—
0
0
59
491
1.25
0.77
3.3
3.0
2.45
2.46
mmol/l
0.13
51
440
60
502
1.24
0.75
1.3
1.2
27.14
33.36
iu/ml
0.25
17
174
5
24
2.10
0.75
1.6
2.2
13.22
13.35
%
—
5
24
37
293
1.30
0.72
2.8
2.2
222.47
163.91
ug/g
0.21
30
239
9
58
1.57
0.70
1.1
1.2
—
—
—
0
0
103
917
1.18
0.69
3.6
3.5
2.35
2.36
mmol/l
0.19
95
807
7
42
1.68
0.69
3.0
3.1
4.69
4.79
e9/l
—
7
42
29
224
1.32
0.67
8.9
7.3
117.31
119.93
g/l
0.26
29
218
24
180
1.36
0.67
3.0
2.3
—
—
—
0
0
7
43
1.64
0.67
3.3
3.1
58.00
61.72
%
—
7
43
26
198
1.34
0.66
3.1
4.0
0.00
1.66
%
—
10
58
23
172
1.36
0.66
3.0
2.6
—
—
—
0
0
7
44
1.60
0.65
1.9
1.8
—
—
—
0
0
20
146
1.39
0.65
1.3
1.3
—
40.87
—
0
10
275
2661
1.25
0.65
5.6
4.5
1.41
1.51
mmol/l
3.90
259
2458
79
691
1.19
0.64
3.7
2.8
—
—
—
0
0
5
29
1.74
0.64
2.0
1.4
19.21
18.76
ug/l
—
5
29
17
233
0.71
0.63
1.4
1.4
—
—
—
0
0
46
382
1.24
0.63
2.9
2.1
2.36
2.37
g/l
0.06
46
351
8
49
1.65
0.62
1.0
1.6
—
—
—
0
0
80
703
1.18
0.62
2.5
2.6
309.93
7002.64
umol/l
3.05
70
608
26
201
1.32
0.61
3.0
3.9
0.54
0.63
%
0.12
12
67
29
228
1.30
0.61
3.0
3.9
0.67
1.16
%
0.77
12
88
8
51
1.58
0.61
11.6
6.3
11.38
11.02
mmol/l
—
8
45
8
51
1.58
0.61
11.8
6.3
105.12
105.29
mmol/l
—
8
45
0
22
0.00
0.59
0.0
14.1
—
843.77
—
0
22
0
22
0.00
0.59
0.0
19.6
—
1502.91
—
0
22
29
229
1.29
0.59
6.7
2.7
1.62
2.27
mmol/l
0.27
24
194
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
11
73
1.53
0.57
3.2
2.8
—
—
—
0
0
43
359
1.23
0.57
3.0
2.1
20.64
21.99
%
0.35
35
305
6
99
0.60
0.52
3.2
4.5
—
—
—
0
0
91
820
1.15
0.52
5.2
3.7
7.41
7.40
ph
0.44
17
155
21
162
1.32
0.51
5.9
4.5
—
—
—
0
0
23
181
1.29
0.49
1.1
1.1
—
—
—
0
0
11
76
1.46
0.48
1.0
1.4
223.80
287.92
ug/g
—
5
47
15
112
1.36
0.45
1.0
1.1
—
—
—
0
0
28
231
1.23
0.43
6.9
2.7
6.02
5.76
kpa
0.45
28
225
5
32
1.57
0.42
1.0
1.1
—
4.87
—
0
15
5
32
1.57
0.42
1.2
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
224.56
—
0
16
8
60
1.34
0.40
2.1
1.7
—
—
—
0
0
5
34
1.48
0.40
1.0
1.1
—
—
—
0
0
47
411
1.17
0.40
3.2
2.7
2.92
3.23
e6/l
0.12
29
209
0
18
0.00
0.40
0.0
2.2
—
10.83
—
0
18
5
35
1.44
0.39
10.8
2.7
—
—
—
0
0
9
68
1.33
0.38
3.1
2.8
1.92
1.53
mg/l
—
9
61
23
189
1.23
0.37
11.3
6.6
—
—
—
0
0
5
37
1.36
0.37
1.0
1.3
—
—
—
0
0
40
349
1.17
0.36
1.2
1.3
—
—
—
0
0
70
637
1.13
0.35
1.7
1.5
20.41
20.96
nmol/l
0.12
61
531
81
744
1.12
0.35
1.8
1.7
1.32
1.37
mmol/l
0.27
72
624
12
155
0.77
0.34
1.7
1.4
—
—
—
0
0
6
47
1.28
0.32
5.7
1.9
43.83
31.88
umol/l
—
6
42
42
372
1.15
0.32
2.7
2.8
0.66
0.77
ug/l
0.44
30
241
35
306
1.16
0.31
8.7
6.0
105.14
104.23
mmol/l
0.46
35
306
78
722
1.11
0.30
3.8
2.9
0.83
0.46
e6/l
0.53
64
525
36
319
1.14
0.28
1.4
1.3
—
—
—
0
0
8
67
1.20
0.26
2.6
2.6
—
—
—
0
0
19
223
0.84
0.25
4.5
3.4
—
—
—
0
0
29
256
1.15
0.24
1.3
1.5
—
—
—
0
0
5
39
1.29
0.23
2.6
1.4
—
—
—
0
0
70
656
1.09
0.21
1.2
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
4.8
—
46.90
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
51
471
1.10
0.21
1.3
1.3
23.87
9.05
u/ml
0.43
22
188
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
30.85
—
0
13
13
108
1.21
0.20
2.5
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
1.79
—
0
14
6
52
1.16
0.19
6.8
2.0
—
—
—
0
0
7
59
1.19
0.18
1.1
2.0
5.42
4.67
mmol/24h
—
7
50
94
982
0.94
0.17
3.9
2.9
—
—
—
0
0
8
68
1.18
0.16
1.3
1.2
—
—
—
0
0
18
158
1.15
0.16
1.6
1.2
—
—
—
0
0
10
83
1.21
0.15
1.6
2.3
12.88
12.56
mg/l
—
10
77
29
316
0.91
0.15
1.4
1.6
—
—
—
0
0
11
94
1.18
0.13
1.1
1.1
—
—
—
0
0
9
109
0.82
0.13
2.7
1.9
4.69
1.40
ug/l
—
9
102
75
719
1.06
0.13
5.1
3.8
0.00
0.00
estimate
0.50
26
241
5
45
1.11
0.10
1.4
1.4
—
—
—
0
0
23
213
1.09
0.09
2.3
2.6
70.23
71.92
e9/l
0.07
16
169
5
47
1.06
0.09
1.6
2.3
—
—
—
0
0
29
273
1.07
0.08
1.5
1.5
—
—
—
0
0
10
113
0.88
0.08
1.0
1.5
—
—
—
0
0
5
62
0.80
0.08
1.8
2.5
7.70
7.96
kpa
—
5
62
17
156
1.09
0.08
8.3
7.7
24.65
25.06
mmol/l
0.22
17
148
7
65
1.08
0.08
1.4
1.3
—
—
—
0
0
7
67
1.05
0.08
1.4
1.3
—
—
—
0
0
7
67
1.05
0.08
1.4
1.3
—
—
—
0
0
8
74
1.08
0.07
1.6
2.7
26.25
25.10
mmol/l
—
8
74
58
561
1.04
0.07
1.4
1.2
1.40
1.51
u/ml
0.05
13
163
115
1128
1.03
0.07
3.2
2.6
108.30
123.01
ug/l
0.57
109
1037
178
1763
1.02
0.05
3.7
2.9
70.65
48.89
u/l
0.51
165
1652
26
250
1.04
0.03
1.5
1.5
—
—
—
0
0
32
311
1.03
0.02
1.9
4.3
2.46
21.21
ug/l
0.79
26
262
16
153
1.05
0.01
1.4
1.5
—
—
—
0
0
18
173
1.04
0.01
1.1
1.2
115.60
167.78
iu/ml
—
5
76
27
264
1.02
0.00
1.3
1.4
—
—
—
0
0
12
122
0.98
0.00
1.6
3.0
—
—
—
0
0
18
182
0.99
0.00
1.4
1.4
—
—
—
0
0
39
388
1.01
0.00
2.3
1.9
—
—
—
0
0
13
129
1.01
0.00
4.1
2.1
0.67
0.66
%
0.06
13
129
13
131
0.99
0.00
2.4
2.3
—
—
—
0
0
13
134
0.97
0.00
4.1
2.1
1.22
1.22
%
0.00
13
134
5
53
0.94
0.00
1.6
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
6
62
0.97
0.00
1.5
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
9.22
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.8
2.5
—
—
—
0
0
15
150
1.00
-0.00
1.3
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
25.86
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
110.64
—
0
7
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
-0.00
8.5
3.2
7.41
7.43
ph
—
6
53
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
50
1.00
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
66
0.91
-0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
20.98
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_XANTHELASMA and mortality.

Females

Parameter HR [95% CI] p-value
H7_XANTHELASMA 1.022 [0.88, 1.19] 0.785
Birth year 0.991 [0.98, 1.0] 0.051

During the follow-up period (1.1.1998 — 31.12.2019), 206 out of 1522 females with H7_XANTHELASMA died.

Males

Parameter HR [95% CI] p-value
H7_XANTHELASMA 1.057 [0.87, 1.28] 0.572
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 120 out of 633 males with H7_XANTHELASMA died.

Mortality risk

Mortality risk for people of age

years, who have H7_XANTHELASMA.

N-year risk Females Males
1 0.096% 0.197%
5 0.591% 1.24%
10 1.353% 3.169%
15 2.571% 6.058%
20 4.416% 9.757%

Relationships between endpoints

↥

Index endpoint: H7_XANTHELASMA – Xanthelasma of eyelid

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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