Acute necrotizing ulcerative gingivitis

AB1_ANUG_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 A69.10
  • Hospital discharge: ICD-10 A69.10
  • Cause of death: ICD-10 A69.10

3 out of 7 registries used, show all original rules.

53

4. Check minimum number of events

None

53

5. Include endpoints

None

53

6. Filter based on genotype QC (FinnGen only)

50

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF13

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 50 34 16
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 35.86 33.42 41.05

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
53
Matched controls
530
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A69.10
ICD-10 Finland
Acute necrotizing ulcerative gingivitis (ANUG)
+∞
75.9
53
*
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
5.0
7.0
21
62

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
24
120
2.83
3.30
2.0
2.8
—
—
—
0
0
14
55
3.10
2.90
3.3
4.2
0.79
0.82
mmol/l
0.72
14
50
44
325
3.08
2.82
4.2
3.8
14.66
14.63
pmol/l
0.02
39
298
8
19
4.76
2.80
1.9
1.3
—
—
—
0
0
9
25
4.12
2.72
2.7
6.7
—
—
—
0
0
8
22
4.09
2.48
6.3
17.7
—
—
—
0
0
18
95
2.35
2.07
2.8
2.6
—
—
—
0
0
12
52
2.69
2.05
2.3
3.2
—
—
—
0
0
8
30
2.95
1.81
2.4
1.8
—
—
—
0
0
10
42
2.70
1.73
7.0
10.4
101.70
105.50
mmol/l
—
10
42
22
135
2.08
1.72
10.4
10.0
1.22
1.22
mmol/l
0.04
22
127
21
128
2.06
1.67
1.7
1.7
87.67
96.50
pmol/l
—
9
65
17
97
2.11
1.59
4.6
2.9
7.88
8.28
mmol/l
0.15
17
88
17
99
2.06
1.50
5.7
6.2
—
—
—
0
0
29
205
1.92
1.47
7.6
4.8
0.19
0.17
e9/l
0.25
24
191
9
41
2.43
1.46
2.0
1.2
—
—
—
0
0
9
42
2.37
1.42
1.3
1.4
—
—
—
0
0
6
23
2.81
1.41
9.0
15.7
0.85
0.75
%
—
6
23
9
44
2.26
1.35
2.0
1.2
—
—
—
0
0
9
44
2.26
1.35
2.1
1.2
—
—
—
0
0
6
24
2.69
1.34
8.2
15.1
1.47
1.66
%
—
6
24
6
25
2.57
1.28
9.0
14.5
83.52
92.59
%
—
6
25
28
203
1.80
1.26
7.6
4.3
0.55
0.54
e9/l
0.05
22
186
28
203
1.80
1.26
7.6
4.3
0.04
0.04
e9/l
0.30
22
186
8
38
2.30
1.25
2.1
1.2
—
—
—
0
0
8
38
2.30
1.25
7.4
23.3
1.52
1.45
mmol/l
—
8
30
27
194
1.80
1.24
8.2
4.6
—
—
—
0
0
29
215
1.77
1.19
8.1
4.3
2.24
1.91
e9/l
0.95
23
202
9
45
2.20
1.12
2.0
1.2
—
—
—
0
0
9
45
2.20
1.12
1.9
1.2
—
—
—
0
0
29
219
1.72
1.08
7.5
4.0
0.00
0.00
estimate
—
5
44
5
22
2.40
1.05
5.0
24.1
—
—
—
0
0
29
221
1.69
1.03
4.9
2.9
0.00
0.00
estimate
—
5
42
16
105
1.75
0.96
1.9
3.2
56.69
54.03
u/l
0.18
16
98
6
28
2.28
0.95
4.7
1.4
10.10
11.07
g/l
—
6
28
8
132
0.54
0.89
7.9
2.7
—
—
—
0
0
46
412
1.88
0.80
17.2
13.2
139.57
139.60
mmol/l
0.06
46
401
31
251
1.57
0.79
3.1
2.6
—
—
—
0
0
46
415
1.82
0.79
17.0
13.2
3.91
3.92
mmol/l
0.12
46
402
13
85
1.70
0.78
5.7
4.7
—
—
—
0
0
7
38
1.97
0.77
9.1
2.1
—
—
—
0
0
19
138
1.59
0.77
6.6
3.4
148.43
61.98
e6/l
0.32
14
98
34
283
1.56
0.76
6.1
4.0
—
75.50
—
0
8
48
440
1.96
0.75
17.9
11.3
19.34
22.41
mg/l
0.32
37
332
12
78
1.70
0.73
3.2
3.3
—
—
—
0
0
5
27
1.94
0.70
18.6
7.9
7.52
7.06
mmol/l
—
5
27
15
108
1.54
0.62
1.9
3.1
20.20
24.29
ng/l
—
5
57
30
250
1.46
0.61
10.8
7.0
4.27
4.02
e9/l
0.21
23
222
27
222
1.44
0.58
5.3
7.1
6.11
6.21
mmol/l
0.20
27
197
6
40
1.56
0.53
1.5
1.4
—
—
—
0
0
24
196
1.41
0.53
10.6
6.3
0.00
0.00
e9/l
-0.00
17
159
24
197
1.40
0.51
2.7
2.1
—
—
—
0
0
7
48
1.53
0.49
1.4
1.7
—
—
—
0
0
7
48
1.53
0.49
1.3
1.2
—
—
—
0
0
5
31
1.67
0.44
2.0
1.4
—
—
—
0
0
5
35
1.47
0.40
1.0
1.9
—
—
—
0
0
13
163
0.73
0.36
2.5
2.2
—
—
—
0
0
33
295
1.31
0.36
4.8
4.0
—
—
—
0
0
13
102
1.36
0.34
7.0
2.7
—
—
—
0
0
25
217
1.29
0.33
4.5
2.9
0.00
0.00
estimate
—
5
49
12
95
1.34
0.29
2.5
1.6
—
—
—
0
0
9
73
1.28
0.27
6.0
2.4
563.44
544.66
mosm/kgh2o
—
9
59
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
8.64
—
0
10
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
19
168
1.20
0.19
2.2
1.8
—
—
—
0
0
7
62
1.15
0.18
1.6
1.6
—
—
—
0
0
15
134
1.17
0.12
2.4
1.8
—
—
—
0
0
14
125
1.16
0.11
3.9
2.4
—
—
—
0
0
5
47
1.07
0.10
1.0
1.1
—
—
—
0
0
7
65
1.09
0.08
1.0
1.3
—
—
—
0
0
39
398
0.92
0.03
17.7
13.9
13.26
13.96
%
1.71
39
392
11
103
1.09
0.02
2.0
1.3
1.77
2.46
g/l
—
6
63
18
174
1.05
0.00
1.9
1.9
—
—
—
0
0
12
118
1.02
0.00
2.8
3.0
0.00
0.00
estimate
—
5
46
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
24.29
—
0
8
0
7
0.00
-0.00
0.0
2.0
—
1.33
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
15
150
1.00
-0.00
2.7
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
69.60
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
91.90
—
0
7
0
5
0.00
-0.00
0.0
1.8
—
1.82
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
106.07
—
0
6
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
9.3
—
762.57
—
0
7
0
5
0.00
-0.00
0.0
3.2
—
13.80
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
83
0.96
-0.00
5.4
2.3
5.40
6.61
e6/l
—
8
75
6
59
1.02
-0.00
2.0
2.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
10.1
—
1483.86
—
0
7

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AB1_ANUG_WIDE – Acute necrotizing ulcerative gingivitis

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).