Mononeuritis multiplex

G6_MONNEURMPLX

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — G58.7 Hospital discharge: ICD-9 — 3545 Cause of death: ICD-10 — G58.7 Cause of death: ICD-9 — 3545 2 out of 7 registries used, show all original rules.	101
4. Check minimum number of events None	101
5. Include endpoints None	101
6. Filter based on genotype QC (FinnGen only)	101

Control definitions (FinnGen only)

Control exclude: G6_NERPLEX

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: G58
Name in latin: Mononeuropathia multiplex

NAME	G6_MONNEURMPLX
CONTROL_EXCLUDE	G6_NERPLEX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G587
HD_ICD_9	3545
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G587
COD_ICD_9	3545
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Mononeuritis multiplex based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	592	287	300
Only index persons	504	254	250
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	54.09	53.93	54.18
Only index persons	52.78	52.21	53.36

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	101	49	52
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	55.56	53.05	57.93

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
87: Matched controls
868

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

G58.7

ICD-10 Finland

Mononeuritis multiplex

+∞

86.4

3545A

ICD-9 Finland

Mononeuritis of upper limb and mononeuritis multiplex, Mononeuritis multiplex

+∞

20.6

G62.9

ICD-10 Finland

Polyneuropathy, unspecified

34.1

18.0

N03AX16

ATC

pregabalin; oral

8.1

15.8

G56.0

ICD-10 Finland

Carpal tunnel syndrome

59.6

13.3

N03AX12

ATC

gabapentin; oral

7.3

11.9

ACC51

NOMESCO Finland

Release of median nerve

+∞

9.5

2402

FHL

External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)

+∞

9.5

TAB00

NOMESCO Finland

Lumbar puncture

15.2

7.6

G57.3

ICD-10 Finland

Lesion of lateral popliteal nerve

+∞

7.4

G56.2

ICD-10 Finland

Lesion of ulnar nerve

+∞

7.4

R20.2

ICD-10 Finland

Paraesthesia of skin

10.0

6.8

ACC59

NOMESCO Finland

Decompression and freeing of adhesions of peripheral nerve: other or unspecified

+∞

6.3

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3004588) Protein electrophoresis panel - Serum or Plasma

8.25

18.35

1.8

2.8

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

12.67

16.93

2.0

1.6

1.1

1.2

g/l

0.97

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

12.57

15.98

1.5

1.1

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

11.82

15.35

1.9

1.6

0.2

g/l

0.75

(3037522) Nuclear Ab [Titer] in Serum

5.35

12.98

1.3

464.0

557.8

titre

—

(3016543) Leukocytes [#/volume] in Cerebral spinal fluid

8.21

10.44

1.4

1.1

477.3

2.5

e6/l

—

(3044290) Cell count panel - Cerebral spinal fluid

8.87

10.41

1.6

1.3

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

7.42

10.14

2.0

4.0

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

8.39

9.96

1.1

1.0

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

11.10

9.72

1.4

1.0

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

10.16

9.15

1.4

1.0

—

(3016018) Differential panel - Cerebral spinal fluid

24.41

8.21

1.7

1.0

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

6.96

7.92

3.8

1.5

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

7.43

7.79

1.2

1.1

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

7.14

6.93

2.5

5.5

0.0

g/l

0.00

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

3.64

6.92

1.4

1.5

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

13.69

6.23

1.1

1.0

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

13.69

6.23

1.1

1.0

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

107

3.24

5.94

1.6

1.7

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

12.16

5.94

1.6

2.4

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

4.08

5.92

1.3

1.5

—

(3002030) Lymphocytes/100 leukocytes in Blood

373

2.71

5.57

10.6

5.7

26.9

0.00

350

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

5.49

5.40

2.5

4.5

40.4

38.7

g/l

0.41

(3023410) Appearance of Cerebral spinal fluid

14.32

5.17

1.9

1.2

—

(3001604) Monocytes [#/volume] in Blood

384

2.59

5.09

10.2

5.3

0.6

e9/l

0.64

328

(3006315) Basophils [#/volume] in Blood

385

2.58

5.05

10.3

5.3

0.0

e9/l

1.40

332

(3017143) Hepatitis C virus Ab [Presence] in Serum

3.32

5.02

1.2

1.5

—

(3019198) Lymphocytes [#/volume] in Blood

395

2.58

5.01

10.2

5.4

1.8

2.2

e9/l

0.53

348

(4027681)

12.26

4.87

1.5

1.1

—

(3018010) Neutrophils/100 leukocytes in Blood

371

2.52

4.87

10.2

5.5

56.4

58.2

0.50

351

(3013115) Eosinophils [#/volume] in Blood

399

2.54

4.85

10.4

5.5

0.2

e9/l

0.54

347

(3044927) Protein electrophoresis panel - Urine

14.88

4.64

1.0

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

9.53

4.36

1.1

—

(3023368) Bacteria identified in Blood by Culture

215

2.42

4.29

5.9

4.1

—

(42870588) Differential panel, method unspecified - Blood

250

2.35

4.14

11.2

5.5

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.62

4.08

1.8

1.6

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

4.51

3.99

2.3

2.4

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

262

2.29

3.97

2.7

3.0

2.3

mmol/l

0.19

227

(3007164) IgA [Mass/volume] in Serum or Plasma

147

2.48

3.88

2.4

1.4

1.7

2.6

g/l

2.27

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

7.13

3.75

1.4

1.2

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

3.65

3.60

1.7

2.2

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

464

2.22

3.53

14.0

9.7

3.9

4.0

e9/l

0.13

404

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

256

2.18

3.50

2.1

3.1

1214.9

1294.4

ng/l

0.05

226

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

3.74

3.44

1.8

1.9

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

9.01

3.31

1.0

—

(4062490)

9.01

3.31

1.0

1.1

—

(3044640) Blood type and Crossmatch panel - Blood

259

2.06

3.04

2.8

2.4

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

10.42

3.01

1.4

1.0

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

348

2.02

3.00

4.5

4.1

35.5

35.4

g/l

0.00

334

(4094501)

5.01

2.98

1.0

1.2

—

(3042936) Bacteria identified in Isolate by Culture

112

2.36

2.96

2.3

1.7

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

127

2.29

2.93

1.9

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

5.69

2.92

1.4

1.9

—

(3019309) Folate [Moles/volume] in Red Blood Cells

165

2.16

2.91

1.8

1.5

943.3

1304.2

nmol/l

1.84

129

(3013707) Erythrocyte sedimentation rate by Westergren method

590

2.16

2.84

7.2

3.9

13.6

12.8

mm/h

0.14

534

(3014148) Varicella zoster virus Ab [Titer] in Serum

8.68

2.78

1.4

1.0

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

6.30

2.74

1.3

1.0

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

398

1.91

2.60

6.7

6.6

1.2

mmol/l

0.05

342

(3019225) pH of Specimen

2.42

2.60

4.8

4.0

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

7.44

2.58

1.0

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

334

1.91

2.57

2.4

1.8

91.9

93.8

pmol/l

0.10

161

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

5.24

2.44

1.0

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

376

1.86

2.42

5.2

4.1

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.30

2.34

3.2

1.5

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

4.10

2.29

1.6

1.2

—

(3045424) Erythrocytes [Presence] in Urine

5.77

2.24

1.0

1.2

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

3.88

2.19

1.4

1.1

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

3.88

2.19

1.3

3.1

206.1

202.6

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

4.48

2.18

1.5

1.4

—

(3000492) Spirometry study

2.38

2.17

1.7

1.6

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

285

1.81

2.15

3.7

3.1

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.00

2.13

0.0

1.2

—

(3037756) Immunofixation for Serum or Plasma

3.92

1.96

2.0

1.9

—

(40760888) Immunoglobulin light chains.free panel - Serum

3.92

1.96

1.8

3.9

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

4.72

1.96

2.4

3.0

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

4.72

1.96

1.0

1.5

—

(3019832) Treponema pallidum Ab [Presence] in Serum

2.48

1.96

1.8

1.6

—

(3003327) Ova and parasites identified in Stool by Light microscopy

3.34

1.92

1.7

1.5

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

339

1.72

1.91

4.3

3.6

29.9

44.9

ng/l

0.61

240

(3002179) Metamyelocytes/100 leukocytes in Blood

2.34

1.87

7.0

3.2

0.5

—

(3037467) Urinalysis macro (dipstick) panel - Urine

559

1.74

1.79

7.1

3.9

—

(3032080) INR in Blood by Coagulation assay

363

1.68

1.77

5.5

7.0

1.0

1.2

inr

3.03

105

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

198

1.73

1.63

3.0

2.3

—

(3021440) Promyelocytes/100 leukocytes in Blood

2.18

1.62

8.4

3.3

0.0

0.1

—

(40758558) Short blood count panel - Blood

216

1.70

1.61

6.8

—

(3025159) Blasts/100 leukocytes in Blood

2.15

1.57

8.3

3.2

0.0

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

747

1.87

1.48

5.5

4.3

1.7

1.9

mu/l

1.20

670

(3005322) IgE [Units/volume] in Serum or Plasma

2.37

1.44

1.7

1.1

220.6

168.2

u/ml

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

516

1.59

1.41

3.4

3.0

42.2

51.6

u/l

0.84

476

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

2.16

1.38

2.5

2.8

5.1

5.2

kpa

0.22

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

3.04

1.37

2.0

1.4

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

3.04

1.37

1.8

1.4

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

3.04

1.37

1.8

1.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

419

1.56

1.37

2.5

2.9

—

(3015736) pH of Urine

318

1.55

1.30

3.0

3.3

—

(3020779) Urea [Moles/volume] in Serum or Plasma

2.03

1.29

5.9

5.5

13.9

10.1

mmol/l

0.83

(3013512) EKG study

237

1.58

1.28

4.1

4.0

—

(4035726)

1.85

1.23

1.2

1.3

—

(3017181) Myelocytes/100 leukocytes in Blood

1.92

1.22

8.7

3.3

0.7

1.0

—

(3026008) Bacteria identified in Urine by Culture

241

1.55

1.18

3.2

2.7

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

592

1.52

1.13

5.1

3.6

14.9

pmol/l

0.01

532

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

199

1.56

1.12

2.0

1.7

2.6

3.2

mg/l

0.98

171

(4010399)

1.90

1.10

1.3

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.34

1.04

1.4

1.3

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.34

1.04

1.8

1.6

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

151

1.58

1.01

2.6

3.1

1608.7

181.9

ng/l

0.42

120

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.95

1.00

4.2

10.9

1.9

1.4

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.95

1.00

1.8

1.4

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.95

1.00

4.2

10.9

0.8

0.7

—

(3000494) Fungus identified in Specimen by Culture

102

1.68

0.97

1.4

1.5

—

(40768797) Stomach Pathology biopsy report

111

1.64

0.95

1.4

1.2

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.71

0.93

2.0

1.6

—

(40760892) CBC W Ordered Manual Differential panel - Blood

173

1.51

0.90

6.3

4.5

—

(3022313) Gas panel - Capillary blood

1.89

0.88

3.1

2.6

—

(3045414) Leukocytes [Presence] in Urine

1.99

0.86

1.2

1.5

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.80

0.85

1.1

1.3

—

(1761868) Lipid panel - Serum or Plasma

270

0.68

0.79

2.8

2.9

—

(3009508) Creatinine [Moles/volume] in Urine

260

1.40

0.78

2.9

3.0

7.1

7.5

mmol/l

0.19

224

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.61

0.77

2.0

1.7

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

109

1.56

0.76

1.3

1.4

9.6

u/ml

—

(3018418) pH of Serum or Plasma

244

1.39

0.74

4.8

4.0

7.4

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.05

0.74

1.8

1.6

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.61

0.73

3.8

3.1

—

(3041096) Erythrocytes [Presence] in Urine by Automated

217

1.40

0.73

5.2

3.0

—

(3029937) Albumin [Presence] in Urine by Test strip

227

1.39

0.71

5.2

3.7

0.0

estimate

0.00

(3035350) Ketones [Presence] in Urine by Test strip

401

1.32

0.66

4.3

3.5

0.0

estimate

0.00

(3018095) Leukocytes [#/volume] in Urine

286

1.34

0.66

5.0

3.5

50.4

63.4

e6/l

0.15

204

(3049717) Cytology report of Urine Cyto stain

1.76

0.64

3.8

3.6

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

827

1.50

0.63

24.6

13.2

22.7

24.4

mg/l

0.19

640

(3021589) Normoblasts [#/volume] in Blood

355

1.31

0.62

13.3

9.4

0.0

e9/l

0.51

291

(3002256) Pathology report gross observation

1.50

0.60

2.1

1.3

—

(40768800) Prostate Pathology biopsy report

0.00

0.60

0.0

1.2

—

(40761535) Cells panel - Urine sediment

1.55

0.56

2.5

3.2

—

(3012516) Albumin [Mass/volume] in Urine

255

1.31

0.55

2.5

3.1

3172.8

66.1

mg/l

0.47

166

(36304419) Bacteria [Presence] in Urine

219

1.32

0.53

4.1

2.9

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.60

0.50

2.6

1.4

—

(3003694) ABO and Rh group [Type] in Blood

221

1.30

0.49

1.5

1.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

119

0.64

0.49

1.3

1.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.53

0.49

2.9

1.7

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

121

1.38

0.48

4.0

2.8

4.8

2.6

e6/l

—

(3021601) Nitrite [Presence] in Urine by Test strip

408

1.23

0.43

5.7

4.6

0.0

estimate

0.00

(1002224) Polysomnography panel

1.54

0.42

1.2

1.1

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

2.3

—

(3030467) Casts [#/volume] in Urine by Automated count

227

1.26

0.40

4.1

3.0

0.6

0.3

e6/l

0.58

170

(3002582) Erythrocytes [#/volume] in Urine

246

1.25

0.40

4.3

3.1

21.2

321.9

e6/l

0.59

186

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

789

1.29

0.38

21.4

12.6

79.7

79.2

ml/min/173m2

0.08

640

(3009261) Glucose [Presence] in Urine by Test strip

412

1.21

0.38

4.4

3.6

0.0

estimate

0.00

(40768804) Tissue Pathology biopsy report

334

1.22

0.38

2.7

2.0

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

865

1.37

0.38

23.7

15.7

139.6

mmol/l

0.03

843

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.42

0.36

5.8

7.6

23.9

25.3

mmol/l

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

813

1.29

0.35

5.3

4.7

5.9

6.0

mmol/l

0.49

748

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

318

1.21

0.34

4.6

3.6

—

(3012544) pH of Venous blood

1.39

0.34

3.8

3.0

—

(3025941) Bacteria identified in Stool by Culture

1.40

0.32

1.1

1.3

—

(3021960) Folate [Moles/volume] in Serum or Plasma

195

1.23

0.32

1.4

1.5

17.2

21.1

nmol/l

0.85

159

(3023103) Potassium [Moles/volume] in Serum or Plasma

870

1.32

0.30

24.0

15.7

4.0

mmol/l

0.14

849

(40761536) Microorganisms panel - Urine sediment

1.27

0.28

6.9

3.6

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

132

1.25

0.28

4.1

2.6

1.9

1.1

e6/l

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.33

0.27

1.6

1.7

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

0.68

0.27

1.4

3.3

—

64.4

—

(3002385) Erythrocyte distribution width [Ratio]

666

0.86

0.27

29.5

16.9

14.0

13.8

0.35

656

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.27

0.26

1.8

2.1

104.2

117.3

ng/l

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

1.31

0.25

2.4

1.6

1.7

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

191

1.19

0.24

2.8

3.6

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.21

0.0

3.2

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.21

0.0

1.2

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.28

0.21

4.1

2.0

4.4

8.7

umol/l

—

(36660697) Celiac disease serology panel - Serum

1.29

0.21

1.2

1.1

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.5

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.21

0.0

1.5

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.21

0.0

1.6

—

(21494434) Karyotype in Bone marrow

0.00

0.21

0.0

1.0

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.7

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.5

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.21

0.0

1.5

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.5

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.20

0.0

3.0

—

66.0

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

265

0.88

0.17

4.1

22.2

21.7

0.05

135

(3000991) Gas panel - Venous blood

1.19

0.17

8.5

9.3

—

(3020682) Albumin/Creatinine [Ratio] in Urine

275

1.13

0.17

3.4

3.9

5.2

8.8

mg/mmol

0.51

167

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

113

1.17

0.14

5.4

8.2

—

(3000963) Hemoglobin [Mass/volume] in Blood

916

0.84

0.13

36.0

20.4

134.1

135.2

g/l

0.27

902

(3026361) Erythrocytes [#/volume] in Blood

916

0.84

0.13

35.9

20.4

4.4

4.5

e12/l

0.12

888

(3010813) Leukocytes [#/volume] in Blood

916

0.84

0.13

35.9

20.4

6.9

6.7

e9/l

0.28

888

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.20

0.13

3.1

2.0

0.2

g/l

—

(3035941) MCH [Entitic mass]

915

0.85

0.12

35.6

20.3

30.3

30.4

0.24

902

(3024731) MCV [Entitic volume]

915

0.85

0.12

35.7

20.3

91.3

91.5

0.11

902

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

818

0.89

0.12

4.5

4.6

4.4

4.6

mmol/l

1.76

759

(3020564) Creatinine [Moles/volume] in Serum or Plasma

885

1.16

0.11

28.1

16.3

82.8

78.2

umol/l

0.64

885

(3007461) Platelets [#/volume] in Blood

914

0.86

0.11

35.8

20.4

247.1

246.7

e9/l

0.02

890

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.17

0.10

7.6

9.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

121

0.90

0.06

1.6

1.3

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

192

0.92

0.06

3.1

2.9

0.5

0.7

ug/l

1.12

139

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

792

1.05

0.02

4.1

4.0

1.3

mmol/l

0.26

729

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

883

1.07

0.02

15.8

10.6

25.9

25.4

u/l

0.14

850

(3009542) Hematocrit [Volume Fraction] of Blood

723

1.03

0.01

22.7

14.9

39.3

39.6

0.08

500

(3044889) 12 lead EKG panel

577

1.01

0.00

4.2

4.0

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

816

1.03

0.00

4.5

1.4

1.5

mmol/l

0.17

752

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

176

1.03

0.00

2.2

1.7

441.4

482.3

pmol/l

0.32

150

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.0

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.2

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

2.1

—

(3025577) Chromium [Mass/volume] in Blood

0.00

0.0

3.6

—

3.9

—

(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3028433) Virus identified in Specimen by Culture

0.00

0.0

1.0

—

(40757494) Bilirubin.total [Moles/volume] in Blood

0.00

0.0

1.7

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.3

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.0

3.0

—

(3017315) Amylase [Enzymatic activity/volume] in Urine

0.00

0.0

1.0

—

1694.5

—

(3011648) Oxygen content in Venous blood

0.00

0.0

1.0

—

10.1

—

(3022145) Colonoscopy Study observation

0.89

0.00

1.6

1.2

—

(3026725) Estradiol (E2) [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

0.3

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3009306) Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma

0.00

0.0

2.8

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.0

1.3

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.0

3.0

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(40761511) CBC panel - Blood by Automated count

860

1.00

0.00

21.2

13.2

—

(3022621) pH of Urine by Test strip

0.86

0.00

2.2

3.3

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

3.8

—

(4146454)

0.00

0.0

2.7

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

0.0

3.6

—

7.6

—

(3014271) Vancomycin [Susceptibility]

0.00

0.0

2.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.3

—

(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.0

—

120.6

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.3

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

0.0

2.4

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.3

—

(21494755) Public health laboratory ask at order entry panel

1.02

0.00

1.3

1.5

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(40765096) Chromosome analysis panel by Banding

0.00

0.0

1.0

—

(3019060) Gas panel - Arterial blood

0.90

0.00

1.4

3.9

—

Mortality – FinRegistry

↥

Association

Association between endpoint G6_MONNEURMPLX and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have G6_MONNEURMPLX.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: G6_MONNEURMPLX – Mononeuritis multiplex

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Mononeuritis multiplex

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints