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Other parasitologically confirmed or unspecified malaria

Endpoint Browser PheWeb

AB1_MALARIA_NOS_WIDE

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — B53, B54
  • Hospital discharge: ICD-10 — B53, B54
  • Hospital discharge: ICD-9 — 08[4]
  • Hospital discharge: ICD-8 — 08[4]
  • Hospital discharge: excluded ICD-9 — 084[0-1]
  • Hospital discharge: excluded ICD-8 — 084[0-1]
  • Cause of death: ICD-10 — B53, B54
  • Cause of death: ICD-9 — 08[4]
  • Cause of death: ICD-8 — 08[4]
  • Cause of death: excluded ICD-9 — 084[0-1]
  • Cause of death: excluded ICD-8 — 084[0-1]

3 out of 7 registries used, show all original rules.

115

4. Check minimum number of events

None

115

5. Include endpoints

None

115

6. Filter based on genotype QC (FinnGen only)

102

Control definitions (FinnGen only)

Control exclude
AB1_PROTOZOAL

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF13

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 102 55 47
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 38.75 35.68 42.35

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
115
Matched controls
1150
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B54
ICD-10 Finland
Unspecified malaria
+∞
97.1
79
*
B50.9
ICD-10 Finland
Plasmodium falciparum malaria, unspecified
+∞
10.6
10
*
R50.9
ICD-10 Finland
Fever, unspecified
3.6
8.1
32
110
0846X
ICD-9 Finland
Malaria, unspecified
+∞
7.4
7
*
J01MA02
ATC
ciprofloxacin; systemic
2.9
7.4
56
282
B53.0
ICD-10 Finland
Plasmodium ovale malaria
+∞
6.3
6
*
08499
ICD-8 Finland
Malaria, Unspecified forms
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
48
248
2.61
5.71
2.6
2.8
—
—
—
0
0
47
246
2.54
5.38
2.7
2.9
0.20
0.35
e6/l
0.59
35
183
50
284
2.35
4.66
3.0
3.0
7.78
33.55
e6/l
1.86
39
221
55
328
2.30
4.55
3.9
3.7
16.64
48.43
e6/l
1.41
40
231
28
142
2.28
3.26
2.4
2.9
2.33
2.21
e6/l
0.03
13
77
33
180
2.17
3.22
2.8
2.5
548.26
565.40
mosm/kgh2o
0.17
27
154
37
222
1.98
2.77
3.5
4.8
—
—
—
0
0
17
77
2.42
2.52
1.4
1.3
—
—
—
0
0
23
127
2.01
2.13
2.0
2.4
—
—
—
0
0
40
266
1.77
2.12
1.8
1.5
—
—
—
0
0
38
252
1.76
2.02
1.7
2.2
—
—
—
0
0
48
343
1.69
1.94
2.6
1.9
—
—
—
0
0
18
97
2.01
1.78
1.5
1.2
—
—
—
0
0
39
275
1.63
1.62
2.5
2.3
—
—
—
0
0
54
415
1.57
1.56
10.8
8.8
0.00
0.00
e9/l
-0.00
43
336
23
144
1.75
1.46
1.7
1.9
—
—
—
0
0
5
16
3.22
1.45
10.6
3.5
43.02
16.22
u/ml
—
5
16
5
16
3.22
1.45
3.4
4.4
54.80
61.31
%
—
5
16
12
60
2.12
1.44
14.4
10.9
—
—
—
0
0
35
247
1.60
1.43
1.6
1.6
1.39
1.38
mmol/l
0.00
30
212
6
24
2.58
1.32
1.2
1.4
—
—
—
0
0
65
542
1.46
1.17
10.6
9.2
3.60
4.05
e9/l
1.01
56
473
10
51
2.05
1.15
1.7
1.2
—
—
—
0
0
24
163
1.60
1.14
2.9
3.0
1209.33
80.99
ng/l
0.67
15
119
11
59
1.96
1.11
8.9
10.4
6.65
8.96
mmol/l
1.15
11
59
8
41
2.02
1.11
18.4
7.2
26.20
24.75
mmol/l
—
8
41
15
92
1.73
1.03
16.7
8.2
105.27
103.82
mmol/l
0.77
15
92
7
36
2.00
0.99
3.4
2.3
—
—
—
0
0
6
28
2.20
0.93
2.0
1.8
—
—
—
0
0
6
28
2.20
0.93
1.2
1.2
—
—
—
0
0
57
479
1.38
0.91
7.4
5.8
1.78
1.84
e9/l
0.22
49
438
8
42
1.97
0.91
23.4
14.0
95.19
94.90
%
—
8
42
18
123
1.55
0.84
2.8
2.1
113.33
122.98
ug/g
0.09
12
101
6
32
1.92
0.83
3.7
2.0
0.65
0.70
%
—
6
32
55
465
1.35
0.82
7.5
5.8
0.04
0.04
e9/l
0.21
47
415
55
465
1.35
0.82
7.5
5.8
0.52
0.56
e9/l
0.86
47
413
6
33
1.86
0.80
3.7
2.0
1.65
1.12
%
—
6
33
8
134
0.57
0.79
1.8
1.4
—
—
—
0
0
16
108
1.56
0.78
1.4
1.5
—
—
—
0
0
28
214
1.41
0.77
2.9
3.3
—
—
—
0
0
51
430
1.33
0.76
8.8
6.3
—
—
—
0
0
5
24
2.13
0.75
3.0
1.5
324.80
301.83
ug/g
—
5
10
31
242
1.38
0.75
3.0
3.4
0.00
0.01
estimate
—
9
81
10
60
1.73
0.75
1.2
1.2
—
—
—
0
0
31
244
1.37
0.72
9.1
6.3
—
—
—
0
0
56
482
1.32
0.72
7.8
6.0
0.18
0.18
e9/l
0.11
51
435
15
103
1.52
0.69
8.1
7.7
1.03
1.03
mmol/l
0.05
15
96
62
695
0.77
0.68
4.9
3.7
8.82
10.50
mm/h
0.60
62
638
5
28
1.82
0.67
1.6
1.3
—
—
—
0
0
106
1010
1.63
0.65
12.3
11.3
—
—
—
0
0
8
49
1.68
0.63
1.0
1.1
—
—
—
0
0
101
955
1.47
0.63
16.5
12.8
29.35
22.38
mg/l
0.97
80
730
11
72
1.58
0.61
3.4
4.8
0.80
0.64
%
—
5
28
11
73
1.56
0.58
3.4
2.8
0.22
0.22
g/l
0.04
11
67
52
454
1.27
0.57
3.5
3.5
0.00
0.00
estimate
—
9
83
6
37
1.66
0.56
1.5
1.5
—
—
—
0
0
17
219
0.74
0.49
1.6
1.3
2.08
2.58
g/l
0.77
11
136
14
103
1.41
0.48
2.7
1.7
—
—
—
0
0
15
112
1.39
0.47
2.1
1.8
—
—
—
0
0
9
126
0.69
0.46
1.2
1.2
—
—
—
0
0
43
376
1.23
0.44
11.4
10.1
1.05
1.20
inr
2.57
15
109
67
614
1.22
0.43
3.3
3.3
—
—
—
0
0
5
32
1.59
0.43
5.0
4.2
22.82
24.78
mmol/l
—
5
32
0
16
0.00
0.41
0.0
4.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
—
—
0
0
0
17
0.00
0.41
0.0
1.8
—
4.45
—
0
12
50
448
1.21
0.40
5.3
5.0
0.00
0.00
estimate
—
10
84
18
143
1.31
0.40
5.9
3.7
0.84
0.81
mmol/l
0.49
18
133
50
451
1.19
0.37
3.5
3.5
0.00
0.00
estimate
—
10
91
6
46
1.32
0.33
1.3
1.3
—
—
—
0
0
12
95
1.29
0.27
1.6
1.3
—
—
—
0
0
17
202
0.81
0.27
2.0
1.7
0.49
1.09
mg/l
3.19
11
156
27
306
0.85
0.27
3.2
3.3
21.50
38.39
ng/l
0.90
20
192
17
142
1.23
0.26
1.9
1.8
—
—
—
0
0
66
622
1.14
0.25
4.7
4.2
—
—
—
0
0
5
37
1.37
0.24
1.4
1.3
—
—
—
0
0
5
39
1.29
0.23
1.4
1.4
—
—
—
0
0
5
39
1.29
0.23
24.4
24.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
2.70
—
0
5
0
10
0.00
0.21
0.0
3.5
—
—
—
0
0
20
228
0.85
0.21
5.0
3.2
231.64
76.70
mg/l
0.53
14
154
0
12
0.00
0.21
0.0
1.2
—
90.33
—
0
12
21
238
0.86
0.21
3.6
2.7
350.44
4476.78
umol/l
1.01
16
209
0
13
0.00
0.21
0.0
1.0
—
0.79
—
0
5
0
13
0.00
0.21
0.0
1.5
—
1.53
—
0
13
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
11.18
—
0
8
0
14
0.00
0.20
0.0
1.0
—
1.31
—
0
6
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
10
81
1.26
0.19
19.0
15.4
12.86
13.32
kpa
—
10
76
10
81
1.26
0.19
19.0
15.3
5.33
5.10
kpa
—
10
76
22
246
0.87
0.18
6.4
3.6
34.91
11.36
mg/mmol
0.40
14
160
11
91
1.23
0.18
1.8
1.7
—
—
—
0
0
7
60
1.18
0.18
1.3
1.3
—
—
—
0
0
22
196
1.15
0.18
1.4
1.7
—
—
—
0
0
7
61
1.16
0.18
1.3
1.2
—
—
—
0
0
7
61
1.16
0.18
1.3
1.2
—
—
—
0
0
7
62
1.14
0.17
1.1
1.3
—
—
—
0
0
8
69
1.17
0.17
6.8
3.3
—
—
—
0
0
8
71
1.14
0.16
23.5
16.8
97.49
96.11
%
—
8
66
10
119
0.83
0.16
1.3
1.4
—
—
—
0
0
87
894
0.89
0.16
3.1
3.8
1.26
1.34
mmol/l
0.56
81
831
30
277
1.11
0.14
5.0
4.3
2.18
1.67
ug/l
0.84
25
249
91
889
1.11
0.13
3.6
4.0
5.64
5.85
mmol/l
1.00
84
823
24
259
0.91
0.11
3.9
3.0
—
—
—
0
0
91
927
0.91
0.10
3.6
4.1
1.48
1.44
mmol/l
0.36
85
867
5
45
1.12
0.10
9.0
15.9
—
—
—
0
0
6
54
1.12
0.09
1.3
1.3
—
—
—
0
0
20
215
0.92
0.08
3.3
3.5
—
—
—
0
0
7
64
1.10
0.08
4.4
4.4
122.86
80.25
ng/l
—
7
58
7
65
1.08
0.08
1.4
2.0
—
—
—
0
0
26
245
1.08
0.08
2.8
3.0
—
—
—
0
0
8
75
1.07
0.07
2.9
1.8
8.74
10.10
g/l
—
8
70
29
305
0.93
0.07
1.9
1.9
91.41
96.25
pmol/l
0.32
12
150
10
110
0.90
0.05
1.4
1.4
—
—
—
0
0
94
930
1.06
0.04
3.6
4.1
4.87
4.70
mmol/l
0.99
88
877
26
267
0.97
0.01
4.0
2.9
8.33
8.47
mmol/l
0.04
21
234
40
393
1.03
0.01
2.5
2.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
238.13
—
0
8
9
89
1.01
0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
2050.00
—
0
5
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.5
—
11.47
—
0
8
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
4.4
—
0.59
—
0
8
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.8
—
768.33
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.6
3.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
9.7
—
1185.83
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1917.00
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
8
86
0.93
-0.00
1.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: AB1_MALARIA_NOS_WIDE – Other parasitologically confirmed or unspecified malaria

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).