Pupillary membranes and other adhesions and disruptions of iris and ciliary body

H7_ADHESIOIRIS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H21.4, H21.5 Hospital discharge: ICD-9 — 3647 Hospital discharge: ICD-8 — 37831 Cause of death: ICD-10 — H21.4, H21.5 Cause of death: ICD-9 — 3647 Cause of death: ICD-8 — 37831 2 out of 7 registries used, show all original rules.	72
4. Check minimum number of events None	72
5. Include endpoints None	72
6. Filter based on genotype QC (FinnGen only)	72

Control definitions (FinnGen only)

Control exclude: H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2

NAME	H7_ADHESIOIRIS
CONTROL_EXCLUDE	H7_SCLERACORNEA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H21[4-5]
HD_ICD_9	3647
HD_ICD_8	37831
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H21[4-5]
COD_ICD_9	3647
COD_ICD_8	37831
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Pupillary membranes and other adhesions and disruptions of iris and ciliary body based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	849	383	459
Only index persons	678	307	371
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	58.21	67.48	50.24
Only index persons	57.65	67.48	49.52

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	72	33	39
Unadjusted period prevalence (%)	0.01	0.01	0.02
Median age at first event (years)	64.68	68.98	61.04

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
66: Matched controls
659

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

H21.5

ICD-10 Finland

Other adhesions and disruptions of iris and ciliary body

+∞

55.1

H21.4

ICD-10 Finland

Pupillary membranes

+∞

14.0

H20.0

ICD-10 Finland

Acute and subacute iridocyclitis

+∞

11.8

H40.5

ICD-10 Finland

Glaucoma secondary to other eye disorders

72.0

11.0

H20.1

ICD-10 Finland

Chronic iridocyclitis

+∞

10.7

Z96.1

ICD-10 Finland

Presence of intraocular lens

7.3

9.9

CJE20

NOMESCO Finland

Phakoemulsification with implantation of artificial lens in posterior chamber

4.8

8.4

152

S01CA01

ATC

dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)

4.6

8.0

174

S01ED51

ATC

timolol, combinations; ophthalmic

7.2

7.7

CHC05

NOMESCO Finland

Iridotomy

+∞

7.4

H25.1

ICD-10 Finland

Senile nuclear cataract

3.8

6.1

136

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3037522) Nuclear Ab [Titer] in Serum

3.23

3.31

1.6

1.3

528.0

297.1

titre

—

(3003396) Base excess in Arterial blood by calculation

2.88

3.04

6.2

6.4

0.6

mmol/l

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

237

2.28

2.93

6.4

7.6

1.2

mmol/l

0.72

195

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

224

2.21

2.75

5.9

5.6

1.2

mmol/l

0.62

197

(3013139) Helicobacter pylori Ag [Presence] in Stool

3.96

2.68

1.0

1.3

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

5.84

2.60

1.7

1.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.79

1.88

1.6

1.3

—

(3015736) pH of Urine

189

1.89

1.79

2.9

3.6

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.77

1.72

1.1

1.7

—

(3045414) Leukocytes [Presence] in Urine

3.35

1.70

1.3

2.1

—

(3037467) Urinalysis macro (dipstick) panel - Urine

353

1.84

1.65

6.0

4.3

—

(3035350) Ketones [Presence] in Urine by Test strip

250

1.78

1.57

3.7

3.9

0.0

estimate

—

(3026008) Bacteria identified in Urine by Culture

145

1.86

1.54

2.7

3.1

—

(3021601) Nitrite [Presence] in Urine by Test strip

252

1.76

1.51

4.8

5.3

0.0

estimate

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.88

1.46

1.0

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

191

1.76

1.44

2.1

2.0

109.1

93.5

pmol/l

0.42

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

165

1.79

1.44

2.4

3.5

1221.7

2035.2

ng/l

0.69

137

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

2.05

1.42

1.4

1.6

—

(3009261) Glucose [Presence] in Urine by Test strip

256

1.71

1.41

3.7

3.8

0.0

estimate

—

(3019060) Gas panel - Arterial blood

2.30

1.39

2.4

3.1

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

2.30

1.39

1.2

1.5

430.4

404.3

nmol/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

151

1.77

1.34

3.7

3.6

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.44

1.32

1.9

2.2

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

232

1.68

1.31

3.4

4.2

22.3

30.3

ng/l

0.60

172

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

2.37

1.29

1.3

1.9

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

119

1.81

1.28

2.3

2.1

—

(3013707) Erythrocyte sedimentation rate by Westergren method

369

1.68

1.26

6.6

3.8

15.8

12.7

mm/h

0.48

336

(3023368) Bacteria identified in Blood by Culture

162

1.72

1.26

3.4

4.2

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

545

1.99

1.19

12.5

9.4

24.1

25.7

u/l

0.34

525

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

394

1.65

1.16

8.8

6.3

85.0

73.8

u/l

1.04

369

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.47

1.16

10.6

6.1

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

2.07

1.13

1.3

2.0

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.95

1.13

2.0

1.5

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.48

1.11

2.4

1.1

—

(36660697) Celiac disease serology panel - Serum

2.17

1.06

1.4

1.2

—

(40761511) CBC panel - Blood by Automated count

541

1.83

1.02

17.0

14.0

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.99

1.02

2.1

1.6

—

(3000330) Specific gravity of Urine by Test strip

2.33

0.96

1.8

3.5

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.33

0.96

1.2

1.3

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

1.83

0.96

1.7

1.2

37.6

42.3

iu/ml

—

(1761868) Lipid panel - Serum or Plasma

187

0.57

0.95

3.5

2.8

—

(3020682) Albumin/Creatinine [Ratio] in Urine

147

1.61

0.94

4.4

3.7

13.4

9.9

mg/mmol

0.14

(3012516) Albumin [Mass/volume] in Urine

139

1.61

0.92

3.8

3.0

5524.5

58.2

mg/l

0.78

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

513

1.67

0.91

20.3

14.4

26.2

24.3

mg/l

0.17

408

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.88

0.89

1.8

—

(3032080) INR in Blood by Coagulation assay

222

1.51

0.88

16.4

8.0

1.7

1.3

inr

—

(3031040) Bacteria [#/volume] in Urine by Automated count

339

1.49

0.85

5.6

4.4

—

264.0

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.84

0.84

1.8

1.9

—

(40768797) Stomach Pathology biopsy report

1.79

0.84

1.2

1.1

—

(3029937) Albumin [Presence] in Urine by Test strip

134

1.57

0.82

4.7

4.1

0.0

estimate

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

170

1.52

0.81

4.9

3.6

2.4

2.3

mmol/l

0.30

142

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

199

1.48

0.78

4.4

4.0

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.63

0.73

1.2

1.3

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.78

0.72

1.7

1.3

—

(3044640) Blood type and Crossmatch panel - Blood

156

1.49

0.72

2.4

2.2

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.74

0.71

1.4

1.7

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

359

1.41

0.67

5.6

3.7

14.9

15.0

pmol/l

0.09

321

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

199

1.39

0.59

2.6

2.3

71.6

75.2

nmol/l

0.35

174

(3007164) IgA [Mass/volume] in Serum or Plasma

1.56

0.59

2.1

1.3

2.3

2.4

g/l

—

(3044889) 12 lead EKG panel

366

1.35

0.56

4.6

3.9

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.53

0.56

1.7

1.8

—

(3019225) pH of Specimen

1.47

0.47

5.0

4.8

—

(3002256) Pathology report gross observation

1.44

0.46

1.1

1.3

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.66

0.44

1.6

1.9

—

(3042936) Bacteria identified in Isolate by Culture

1.46

0.44

2.6

1.8

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.44

0.43

1.7

1.9

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.37

0.42

1.7

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.00

0.41

0.0

1.7

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

0.00

0.40

0.0

1.6

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

201

1.29

0.39

4.4

4.3

2.0

2.2

ug/l

0.14

184

(3000991) Gas panel - Venous blood

1.50

0.37

12.5

7.7

—

(3000494) Fungus identified in Specimen by Culture

1.43

0.36

1.5

—

(3013512) EKG study

164

0.75

0.35

4.9

4.6

—

(3018095) Leukocytes [#/volume] in Urine

195

1.26

0.34

1.9

3.9

118.2

119.6

e6/l

0.00

138

(40761536) Microorganisms panel - Urine sediment

1.33

0.34

5.7

4.2

—

(3000492) Spirometry study

1.38

0.32

1.4

1.3

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.37

0.32

2.0

2.6

2.9

1.5

e6/l

—

(3012544) pH of Venous blood

1.33

0.31

1.3

4.3

—

(3022145) Colonoscopy Study observation

1.33

0.31

1.0

1.1

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

188

1.25

0.30

2.0

3.4

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

446

1.23

0.29

6.7

4.5

2.0

mu/l

0.06

401

(3021589) Normoblasts [#/volume] in Blood

237

1.22

0.29

8.4

11.2

0.0

e9/l

0.00

186

(3003694) ABO and Rh group [Type] in Blood

123

1.28

0.28

2.1

1.4

—

(3002582) Erythrocytes [#/volume] in Urine

171

1.23

0.27

1.6

3.4

57.7

439.3

e6/l

0.50

131

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

231

1.20

0.24

4.7

3.9

—

(40758558) Short blood count panel - Blood

136

1.23

0.22

4.4

5.6

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

0.21

0.0

1.5

—

6.6

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

0.21

0.0

1.5

—

144.3

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

0.00

0.21

0.0

2.5

—

5.3

—

(3012441) Differential panel - Pleural fluid

0.00

0.21

0.0

1.9

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

0.00

0.21

0.0

4.2

—

65.9

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.1

—

(40768806) Pleura Pathology biopsy report

0.00

0.21

0.0

1.8

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

546

1.21

0.20

21.4

16.8

84.0

83.1

umol/l

0.10

546

(3023520) Reticulocytes [#/volume] in Blood

1.22

0.20

14.5

2.7

89.5

66.6

e9/l

—

(4035726)

1.19

0.20

1.0

1.4

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

486

1.17

0.18

17.6

14.2

74.0

78.3

ml/min/173m2

0.75

403

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.24

0.16

1.7

2.8

0.4

3.2

e6/l

—

(40760892) CBC W Ordered Manual Differential panel - Blood

103

1.20

0.15

6.5

5.6

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

469

1.14

0.15

6.9

6.0

40.7

40.9

mmol/mol

0.03

428

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

321

0.89

0.14

2.4

2.9

—

(40768804) Tissue Pathology biopsy report

198

0.88

0.12

1.6

2.1

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

114

0.86

0.10

3.7

3.5

—

(3030467) Casts [#/volume] in Urine by Automated count

155

1.13

0.10

1.9

3.2

0.1

0.4

e6/l

1.35

116

(3027945) Reticulocytes/100 erythrocytes in Blood

1.09

0.08

7.0

2.4

2.3

1.7

—

(36304419) Bacteria [Presence] in Urine

148

1.10

0.07

1.7

3.2

—

(3009542) Hematocrit [Volume Fraction] of Blood

463

0.93

0.07

25.1

14.8

38.8

39.8

0.29

328

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

159

1.09

0.05

3.1

4.1

14.7

20.8

—

(42870588) Differential panel, method unspecified - Blood

170

1.08

0.04

9.6

5.3

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

519

1.01

0.00

5.5

4.8

2.6

2.7

mmol/l

0.30

465

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

492

0.99

0.00

4.2

3.8

1.3

mmol/l

0.00

438

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

506

1.03

0.00

4.9

4.2

1.4

mmol/l

0.29

455

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

494

0.97

0.00

5.7

4.4

6.4

6.0

mmol/l

0.66

444

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.0

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.4

—

(3011544) Albumin [Mass/volume] in Pleural fluid

0.00

0.0

1.0

—

18.6

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.0

1.3

—

(3011648) Oxygen content in Venous blood

0.00

0.0

3.4

—

12.0

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

27.2

—

1229.6

—

(44790047)

0.00

0.0

2.0

—

(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

12.1

—

(44806118)

0.00

0.0

2.0

—

(44790048)

0.00

0.0

2.0

—

(44790049)

0.00

0.0

2.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.0

1.0

—

53.1

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.6

—

(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.9

—

11.7

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

0.0

1.4

—

11.6

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

21.2

—

811.8

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.0

1.2

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

7.0

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.0

—

(3017569) Oxygen content in Arterial blood

0.00

0.0

15.6

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.3

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.5

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.3

—

(3010726) Horse dander IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma

0.00

0.0

1.3

—

32.1

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.84

0.00

2.6

3.4

—

(3035880) pH of Pleural fluid

0.00

0.0

1.1

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.0

1.3

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

4.3

—

3.2

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.3

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.3

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.0

1.0

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

510

1.00

0.00

4.8

4.3

4.4

4.5

mmol/l

0.24

461

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.1

—

(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum

0.00

0.0

1.7

—

74.1

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.0

3.1

—

16.8

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.5

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

1.7

—

89.1

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.3

—

(3045788) Cell count panel - Pleural fluid

0.00

0.0

1.7

—

Mortality – FinRegistry

↥

Association

Association between endpoint H7_ADHESIOIRIS and mortality.

Females

Parameter	HR [95% CI]	p-value
H7_ADHESIOIRIS	1.018 [0.78, 1.33]	0.893
Birth year	0.993 [0.98, 1.0]	0.116

During the follow-up period (1.1.1998 — 31.12.2019), 89 out of 298 females with H7_ADHESIOIRIS died.

Males

Parameter	HR [95% CI]	p-value
H7_ADHESIOIRIS	1.279 [0.92, 1.78]	0.144
Birth year	0.987 [0.98, 1.0]	0.014

During the follow-up period (1.1.1998 — 31.12.2019), 79 out of 348 males with H7_ADHESIOIRIS died.

Mortality risk

Mortality risk for people of age

years, who have H7_ADHESIOIRIS.

N-year risk	Females	Males
1	0.083%	0.236%
5	0.665%	1.563%
10	1.45%	3.976%
15	2.724%	7.568%
20	4.764%	12.717%

Relationships between endpoints

↥

Index endpoint: H7_ADHESIOIRIS – Pupillary membranes and other adhesions and disruptions of iris and ciliary body

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Pupillary membranes and other adhesions and disruptions of iris and ciliary body

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints