Acute disseminated encephalitis/encephalomyelitis

G6_ADEM

acute disseminated encephalomyelitis: An encephalomyelitis characterized by inflammation located_in brain and located_in spinal cord that damages myelin. It usually occurs after viral infection, but also following vaccination, bacterial or parasitic infection.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — G04.0# Hospital discharge: ICD-9 — 3235A Hospital discharge: ICD-8 — 32300 Cause of death: ICD-10 — G04.0# Cause of death: ICD-9 — 3235A Cause of death: ICD-8 — 32300 2 out of 7 registries used, show all original rules.	66
4. Check minimum number of events None	66
5. Include endpoints None	66
6. Filter based on genotype QC (FinnGen only)	66

Control definitions (FinnGen only)

Control exclude: G6_NEUINFL

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: G04
Name in latin: Encephalitis disseminata acuta

NAME	G6_ADEM
CONTROL_EXCLUDE	G6_NEUINFL
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G040
HD_ICD_9	3235A
HD_ICD_8	32300
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G040
COD_ICD_9	3235A
COD_ICD_8	32300
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Acute disseminated encephalitis/encephalomyelitis based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	676	304	364
Only index persons	537	257	280
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	21.71	24.51	18.75
Only index persons	20.47	23.38	17.79

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	66	40	26
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	25.74	24.83	27.13

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
58: Matched controls
578

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

32300

ICD-8 Finland

Encephalitis, myelitis and encephalomyelitis, Encephalitis postinfectiosa

+∞

36.3

G04.0

ICD-10 Finland

Acute disseminated encephalitis

+∞

31.0

TAB00

NOMESCO Finland

Lumbar puncture

25.7

10.4

G04.9

ICD-10 Finland

Encephalitis, myelitis and encephalomyelitis, unspecified

+∞

9.6

AA1DG

NOMESCO Finland

Very extensive MRI examination of brain with high intensity magnet

19.0

7.6

G40.9

ICD-10 Finland

Epilepsy, unspecified

19.7

7.0

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3016018) Differential panel - Cerebral spinal fluid

15.41

4.68

1.3

1.0

—

(3044290) Cell count panel - Cerebral spinal fluid

7.25

4.14

1.7

1.0

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

13.00

3.84

1.3

1.0

—

(4027681)

13.00

3.84

1.7

1.2

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

8.53

3.65

1.0

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

6.96

3.27

1.0

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

6.38

3.11

1.0

—

(3032080) INR in Blood by Coagulation assay

176

2.03

2.00

5.6

6.1

1.0

1.1

inr

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

176

2.03

2.00

5.8

3.4

20.2

25.3

ng/l

0.24

113

(3018418) pH of Serum or Plasma

136

2.06

1.92

3.4

3.9

7.4

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

4.41

1.86

1.0

1.9

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.89

1.79

8.1

3.9

25.8

24.7

mmol/l

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.56

1.79

1.8

1.5

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

3.36

1.70

1.2

1.8

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

3.19

1.62

1.7

1.0

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.67

1.50

1.6

2.5

—

(3019225) pH of Specimen

2.44

1.47

4.9

5.0

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

3.29

1.46

6.2

1.9

3.2

3.8

g/l

—

(42870588) Differential panel, method unspecified - Blood

167

1.80

1.41

8.3

6.2

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

2.76

1.40

4.8

1.7

88.5

93.9

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.07

1.35

2.1

1.8

—

(3044640) Blood type and Crossmatch panel - Blood

160

1.79

1.35

2.9

2.2

—

(3000991) Gas panel - Venous blood

2.46

1.32

1.8

6.6

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

188

1.74

1.31

4.8

2.9

—

(3022313) Gas panel - Capillary blood

2.92

1.31

8.2

5.2

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.92

1.31

3.6

36.8

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

145

1.78

1.28

5.1

2.4

220.3

245.6

u/l

0.06

138

(3023368) Bacteria identified in Blood by Culture

112

1.83

1.25

4.4

5.1

—

(3037467) Urinalysis macro (dipstick) panel - Urine

364

1.74

1.25

4.9

4.1

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

2.00

1.18

3.4

2.1

28.8

28.5

0.13

(44816559) Phosphatidylethanol [Mass/volume] in Blood

2.62

1.17

1.2

1.1

—

(3019198) Lymphocytes [#/volume] in Blood

260

1.63

1.13

8.5

6.9

1.9

e9/l

0.18

235

(36304419) Bacteria [Presence] in Urine

150

1.70

1.12

4.4

2.7

—

(3009261) Glucose [Presence] in Urine by Test strip

272

1.61

1.07

4.0

3.4

0.0

estimate

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

109

1.75

1.07

2.8

2.3

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

2.37

1.05

1.2

1.5

—

326.7

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

2.37

1.05

1.4

1.9

0.2

12.1

ug/l

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

2.37

1.05

1.6

1.3

0.2

g/l

—

(3001604) Monocytes [#/volume] in Blood

256

1.58

1.00

8.6

6.9

0.6

e9/l

0.28

228

(3006315) Basophils [#/volume] in Blood

256

1.58

1.00

8.6

6.9

0.0

e9/l

0.12

228

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.88

0.99

1.7

1.6

—

(3015736) pH of Urine

219

1.58

0.98

2.9

3.1

—

(3018095) Leukocytes [#/volume] in Urine

201

1.58

0.97

4.4

3.3

15.1

e6/l

0.00

135

(3021601) Nitrite [Presence] in Urine by Test strip

271

1.53

0.88

5.5

4.7

0.0

estimate

—

(3035350) Ketones [Presence] in Urine by Test strip

271

1.53

0.88

4.0

3.4

0.0

estimate

—

(3021589) Normoblasts [#/volume] in Blood

234

1.52

0.85

11.2

10.3

0.0

e9/l

0.00

190

(3019150) Specific gravity of Urine by Refractometry

116

1.63

0.85

3.5

1.0

kg/l

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.85

0.85

2.4

2.1

2.7

2.5

g/l

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.77

0.81

2.5

2.0

13.3

14.9

umol/l

0.24

(3008898) HLA-B27 [Presence]

0.00

0.81

0.0

1.1

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.00

0.80

0.0

2.1

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

2.27

0.78

1.6

1.3

1.1

1.2

g/l

—

(3014007) Fractional oxyhemoglobin in Arterial blood

2.27

0.78

1.4

8.5

93.7

92.6

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.74

0.77

3.8

2.0

228.3

380.1

nmol/l

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

1.74

0.77

2.7

2.1

19.6

26.2

—

(3044889) 12 lead EKG panel

336

1.48

0.77

4.3

3.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

173

1.51

0.76

2.0

1.8

108.3

102.3

pmol/l

0.18

(3041096) Erythrocytes [Presence] in Urine by Automated

155

1.52

0.76

4.6

3.1

—

(3013512) EKG study

157

1.50

0.71

4.5

3.4

—

(3019060) Gas panel - Arterial blood

1.92

0.70

3.6

21.1

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

113

1.55

0.69

2.3

1.8

1.5

0.9

mg/l

0.41

(3026008) Bacteria identified in Urine by Culture

149

1.49

0.69

4.1

2.8

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

1.63

0.68

1.5

1.7

409.1

525.7

pmol/l

0.87

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.78

0.65

2.2

1.7

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.68

0.64

1.8

1.7

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

207

1.42

0.63

4.4

3.4

—

(40768793) Breast Pathology biopsy report

0.00

0.61

0.0

1.2

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.55

0.57

1.4

2.0

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.58

0.53

1.5

1.6

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.55

0.53

1.7

—

(3009508) Creatinine [Moles/volume] in Urine

111

1.45

0.52

3.8

2.6

6.0

7.7

mmol/l

1.40

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

120

1.44

0.52

1.3

1.6

—

(40761536) Microorganisms panel - Urine sediment

1.62

0.51

7.0

3.3

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

535

1.48

0.49

18.2

13.9

3.9

4.0

mmol/l

0.63

518

(3007164) IgA [Mass/volume] in Serum or Plasma

123

1.40

0.46

2.0

1.3

2.6

2.2

g/l

0.34

(46235355) HIV 1 and 2 tests - Meaningful Use set

123

1.40

0.46

2.4

1.9

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

408

1.32

0.42

7.5

7.7

73.7

78.6

u/l

0.47

382

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.42

0.0

1.5

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.42

0.0

3.7

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

308

1.29

0.41

8.1

12.0

4.5

3.9

e9/l

0.76

272

(4034850)

0.00

0.40

0.0

11.3

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

192

1.30

0.39

2.6

3.1

34.3

28.6

u/l

0.77

180

(3042936) Bacteria identified in Isolate by Culture

1.35

0.39

4.0

2.7

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.51

0.37

1.5

7.2

106.7

103.6

mmol/l

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.44

0.37

1.4

1.7

—

(3029937) Albumin [Presence] in Urine by Test strip

138

1.31

0.35

5.2

3.5

0.0

estimate

—

(3000492) Spirometry study

1.33

0.34

1.5

1.6

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

415

1.27

0.33

3.2

3.3

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

531

1.36

0.32

18.7

14.0

139.2

139.8

mmol/l

0.86

514

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

104

1.31

0.29

1.4

1.7

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.30

0.24

4.1

2.5

0.6

0.7

e6/l

—

(4035726)

1.34

0.24

1.2

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.34

0.24

4.6

3.3

0.2

g/l

—

(3025941) Bacteria identified in Stool by Culture

1.30

0.23

1.2

1.4

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.24

0.22

3.0

2.0

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

253

1.19

0.22

3.8

4.6

—

(40760892) CBC W Ordered Manual Differential panel - Blood

127

1.23

0.22

7.9

6.6

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.29

0.22

4.4

2.6

1.0

2.6

e6/l

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

65.1

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.21

0.0

1.3

—

(3024731) MCV [Entitic volume]

613

0.77

0.21

25.1

18.6

90.2

90.5

0.15

603

(3012544) pH of Venous blood

1.30

0.21

2.3

3.7

—

(3035941) MCH [Entitic mass]

613

0.77

0.21

25.0

18.6

30.0

30.2

0.48

603

(3000963) Hemoglobin [Mass/volume] in Blood

613

0.77

0.21

25.5

18.8

135.6

137.3

g/l

0.45

603

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

4.5

—

11.3

—

(3023351) European house dust mite IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

0.1

—

(40768804) Tissue Pathology biopsy report

206

1.18

0.19

2.6

1.9

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.26

0.18

3.0

1.9

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.20

0.17

2.9

1.6

—

(40768797) Stomach Pathology biopsy report

1.20

0.17

1.5

1.3

—

(40758558) Short blood count panel - Blood

131

1.19

0.16

7.1

8.4

—

(40761511) CBC panel - Blood by Automated count

579

0.89

0.16

16.7

11.0

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

104

1.19

0.13

1.3

1.4

—

(1761868) Lipid panel - Serum or Plasma

222

1.13

0.12

2.2

2.7

—

(36660697) Celiac disease serology panel - Serum

1.12

0.10

1.6

1.1

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.07

0.09

1.2

1.8

—

(3009542) Hematocrit [Volume Fraction] of Blood

516

1.14

0.09

14.5

12.9

41.6

40.8

0.66

409

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.12

0.09

10.2

3.5

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

547

1.16

0.09

19.4

13.1

18.2

20.0

mg/l

0.23

405

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.04

0.08

3.7

6.9

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.04

0.08

6.0

1.5

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

127

1.13

0.08

2.9

3.2

—

(3002256) Pathology report gross observation

1.03

0.08

1.6

1.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.08

0.08

3.1

1.8

—

(21494755) Public health laboratory ask at order entry panel

1.06

0.08

1.3

—

(3002385) Erythrocyte distribution width [Ratio]

470

1.08

0.04

17.6

15.4

13.4

13.5

0.32

459

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

133

1.07

0.02

2.4

2.9

845.3

895.4

ng/l

—

109

(3003694) ABO and Rh group [Type] in Blood

174

1.05

0.00

1.7

1.4

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

275

1.03

0.00

5.9

7.1

8.1

10.1

umol/l

1.51

262

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

11.2

—

0.7

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

4.2

—

33.0

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.2

—

(3011436) Histone Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

0.0

2.0

—

57.6

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3017315) Amylase [Enzymatic activity/volume] in Urine

0.00

0.0

1.4

—

137.0

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

1.4

—

12.8

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

1.4

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

0.3

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.0

3.0

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma

0.00

0.0

1.2

—

108.2

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.0

1.4

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

23.8

—

(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

11.0

—

1235.5

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.1

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.0

8.8

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

7.7

—

180.3

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

8.2

—

765.8

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.0

4.4

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(3022145) Colonoscopy Study observation

0.92

0.00

1.8

1.3

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.0

1.3

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

2.1

—

3.0

—

(3000494) Fungus identified in Specimen by Culture

0.92

0.00

1.7

1.8

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

2.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint G6_ADEM and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have G6_ADEM.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: G6_ADEM – Acute disseminated encephalitis/encephalomyelitis

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Acute disseminated encephalitis/encephalomyelitis

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints