Granulosa cell carcinoma of ovary

C3_OVARY_GRANULOSA

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule only females	293373
2. Check conditions None	293373
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Cancer registry: Topography ICD-O-3 — C56 Cancer registry: Morphology ICD-O-3 — 8620 Cancer registry: Behaviour codes — 3 1 out of 7 registries used, show all original rules.	101
4. Check minimum number of events None	101
5. Include endpoints None	101
6. Filter based on genotype QC (FinnGen only)	101

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze: DF9

NAME	C3_OVARY_GRANULOSA
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO	C56
CANC_TOPO_EXCL
CANC_MORPH	8620
CANC_MORPH_EXCL
CANC_BEHAV	3

Similar endpoints

↥

List of similar endpoints to Granulosa cell carcinoma of ovary based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Granulosa cell carcinoma of ovary, excluding all cancers (controls excluding all cancers)

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	101	101	-
Unadjusted period prevalence (%)	0.03	0.03	-
Median age at first event (years)	55.36	55.36	-

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
96: Matched controls
958

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

8620/3-C56.9

ICD-O-3

Adult granulosa cell tumor of ovary of ovary

+∞

138.3

C56.92

ICD-10 Finland

Malignant ovarian tumor, sex chord stroma derived

+∞

111.2

D39.10

ICD-10 Finland

Tumor of uncertain or unknown nature in the ovary without histology

81.1

45.1

B01AB10

ATC

tinzaparin; parenteral

21.9

28.2

JAL31

NOMESCO Finland

Laparoscopic omentectomy

333.2

26.0

128

Kela drug reimbursment

Cancers of female genital organs

55.4

21.7

C56.91

ICD-10 Finland

Malignant granulosa cell tumor in ovary

+∞

20.5

LAF11

NOMESCO Finland

Laparoscopic bilateral salpingo-oophorectomy

13.7

19.8

JAL00

NOMESCO Finland

Biopsy of peritoneum

117.1

18.3

JN4BD

NOMESCO Finland

Extensive body CT

12.5

18.0

LC2BE

NOMESCO Finland

Transvaginal ultrasound examination of uterus, parametria and lower abdomen

7.0

17.3

267

B01AB05

ATC

enoxaparin; parenteral

6.8

17.2

195

JAL30

NOMESCO Finland

Omentectomy

49.8

17.1

LAF01

NOMESCO Finland

Laparoscopic unilateral salpingo-oophorectomy

20.8

16.3

R19.0

ICD-10 Finland

Intra-abdominal and pelvic swelling, mass and lump

25.4

16.0

LX1AE

NOMESCO Finland

Gynecological ultrasound examination as part of clinical examination

7.2

14.7

LAF10

NOMESCO Finland

Bilateral salpingo-oophorectomy

20.3

14.2

JAL01

NOMESCO Finland

Laparoscopic biopsy of peritoneum

87.6

14.0

WX302

NOMESCO Finland

Thoracal epidural anesthesy

14.0

13.4

WX602

NOMESCO Finland

Repeated or continuing anesthesia shots throug a catheter

9.2

12.9

WX402

NOMESCO Finland

General anaesthesia

6.2

11.9

C56.00

ICD-10 Finland

Malignant tumor of the ovary without histology

122.9

10.6

JAL20

NOMESCO Finland

Excision or destruction of lesion of peritoneum

122.9

10.6

LCD01

NOMESCO Finland

Total laparoscopic hysterectomy

11.5

10.3

LX1XE

NOMESCO Finland

Other gynecological ultrasound examination

12.7

10.3

LCD00

NOMESCO Finland

Hysterectomy

7.8

9.9

WX404

NOMESCO Finland

Intravenous generell anesthesy

4.6

9.8

129

LCD04

NOMESCO Finland

Laparoscopic hysterectomy

7.0

8.8

WZC20

NOMESCO Finland

Multidisciplinary treatment meeting

7.4

7.7

LAF16

NOMESCO Finland

Excision of uterus, adnexes and lymph nodes for treatment of ovarian cancer

86.5

7.5

JN4AD

NOMESCO Finland

Body CT examination

7.7

7.5

JAP00

NOMESCO Finland

Freeing of adhesions in the peritoneal cavity

24.5

6.8

H02AB02

ATC

dexamethasone; systemic

5.0

6.8

JEA00

NOMESCO Finland

Appendectomy

6.4

6.7

LC2DE

NOMESCO Finland

Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods

6.9

6.7

D39.13

ICD-10 Finland

Uncertain growth nature of the ovarian tumor, sex chord derived

+∞

6.3

WC125

NOMESCO Finland

Demanding cytostatic therapy of local tumor recidive

+∞

6.3

A04AA01

ATC

ondansetron; systemic, rectal

5.7

6.1

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(4281824)

43.50

61.14

1.2

1.0

—

(4035726)

9.09

26.50

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

411

5.55

12.63

4.7

3.8

—

(3023323) Follitropin [Units/volume] in Serum or Plasma

5.94

11.94

3.0

1.4

iu/l

30.6

22.8

0.61

(3044640) Blood type and Crossmatch panel - Blood

264

4.14

11.28

2.0

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

4.42

9.88

1.3

4.8

ug/l

7.4

6.7

0.04

(3033658) Prothrombin time (PT) actual/Normal

203

3.32

7.98

2.9

3.3

102.6

96.7

0.86

196

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

205

3.28

7.82

2.0

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

5.86

7.20

1.9

1.4

u/l

38.2

206.7

—

(40768804) Tissue Pathology biopsy report

397

3.04

6.57

2.9

2.0

—

(3002256) Pathology report gross observation

114

3.17

5.87

1.2

—

(3009261) Glucose [Presence] in Urine by Test strip

450

2.81

5.48

3.1

3.6

estimate

0.0

0.49

(3021601) Nitrite [Presence] in Urine by Test strip

446

2.73

5.24

3.5

4.9

estimate

0.0

0.00

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

7.13

3.75

1.0

1.6

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

4.48

2.74

1.0

1.4

—

(40758558) Short blood count panel - Blood

228

1.98

2.62

6.3

7.9

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

111

2.26

2.60

3.7

2.7

mmol/l

0.8

0.46

105

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

827

2.97

2.48

14.3

11.3

ml/min/173m2

81.7

83.4

0.36

654

(3032080) INR in Blood by Coagulation assay

284

1.90

2.46

14.5

7.0

inr

1.2

1.1

0.24

(3003694) ABO and Rh group [Type] in Blood

243

1.90

2.39

1.3

1.4

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

3.88

2.19

2.0

2.7

144.9

177.2

—

(3000991) Gas panel - Venous blood

2.75

2.18

12.5

7.3

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

2.31

2.04

1.7

2.7

ml/min/173m2

56.7

69.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.22

1.98

3.8

3.5

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

232

1.78

1.90

1.6

1.4

—

(3019060) Gas panel - Arterial blood

2.66

1.90

4.8

4.6

—

(3018095) Leukocytes [#/volume] in Urine

296

1.72

1.84

2.4

3.5

e6/l

83.8

70.0

0.12

194

(3013650) Neutrophils [#/volume] in Blood by Automated count

517

1.72

1.81

10.4

9.3

e9/l

3.5

3.8

0.93

464

(3014007) Fractional oxyhemoglobin in Arterial blood

2.81

1.76

15.5

8.5

93.0

95.0

—

(3020891) Body temperature

3.05

1.75

5.0

3.9

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

397

0.56

1.75

2.3

2.2

nmol/l

81.2

79.1

0.12

349

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.71

1.70

15.4

8.1

0.9

0.8

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.71

1.70

15.5

8.1

1.3

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

881

2.81

1.63

17.3

12.7

mmol/l

139.9

0.01

851

(3030467) Casts [#/volume] in Urine by Automated count

216

1.70

1.61

2.1

2.7

e6/l

0.4

0.10

152

(36304419) Bacteria [Presence] in Urine

219

1.68

1.52

2.1

2.6

—

(3029937) Albumin [Presence] in Urine by Test strip

233

1.62

1.38

3.8

4.0

estimate

0.0

0.00

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.12

1.33

1.4

1.8

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

201

1.62

1.30

3.0

3.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

274

1.55

1.25

2.6

2.8

—

(3004616) Nuclear Ab [Presence] in Serum

2.57

1.16

1.6

1.3

—

(3002582) Erythrocytes [#/volume] in Urine

242

1.54

1.16

2.0

2.9

e6/l

61.3

24.8

0.50

178

(3044889) 12 lead EKG panel

591

1.53

1.15

3.8

3.4

—

(40768797) Stomach Pathology biopsy report

121

0.46

1.14

1.8

1.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

200

0.55

1.14

1.6

1.5

—

(3009508) Creatinine [Moles/volume] in Urine

241

0.60

1.05

2.3

2.8

mmol/l

6.9

7.1

0.05

192

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

877

0.61

1.04

4.3

4.8

mmol/l

2.7

2.9

0.67

812

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

125

1.64

1.03

1.6

2.4

e6/l

2.9

1.1

0.72

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

866

1.93

1.03

12.8

12.1

mg/l

26.5

19.9

1.15

636

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.99

0.0

2.6

—

0.0

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.99

0.0

2.6

—

0.0

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.99

0.0

2.6

—

0.0

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.99

0.0

2.6

—

38.0

—

(3017044) Thyrotropin receptor Ab [Units/volume] in Serum

0.00

0.99

0.0

1.4

—

8.9

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.01

0.99

18.6

7.2

—

(3020682) Albumin/Creatinine [Ratio] in Urine

233

0.63

0.90

3.2

3.8

mg/mmol

13.8

7.0

—

127

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

2.06

0.88

1.5

3.3

u/ml

14.2

39.8

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

121

0.55

0.84

1.6

1.7

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

0.48

0.83

4.4

2.5

14.9

23.1

—

(3035350) Ketones [Presence] in Urine by Test strip

439

1.38

0.83

3.3

3.6

estimate

0.0

0.00

(3004789) Transferrin [Mass/volume] in Serum or Plasma

100

0.47

0.82

4.4

2.5

g/l

2.3

2.4

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.87

0.80

3.2

2.5

50.1

44.8

—

(3012516) Albumin [Mass/volume] in Urine

227

0.65

0.80

2.4

3.1

mg/l

4568.8

42.2

—

126

(3022313) Gas panel - Capillary blood

0.00

0.79

0.0

4.6

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

866

0.67

0.75

3.9

4.3

mmol/l

4.8

4.9

0.21

810

(3012544) pH of Venous blood

1.67

0.75

1.2

3.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

331

0.71

0.74

1.5

1.9

pmol/l

85.5

102.3

0.95

151

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

2.05

0.74

1.0

1.3

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.05

0.74

1.0

1.4

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

1.63

0.73

2.6

3.1

kpa

6.5

5.8

—

(3021589) Normoblasts [#/volume] in Blood

377

1.35

0.73

8.1

9.0

e9/l

0.0

0.50

310

(3007853) Bacteria identified in Skin by Aerobe culture

1.61

0.69

1.5

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.67

0.68

3.3

1.3

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

1.83

0.67

3.2

2.2

mmol/l

27.4

25.2

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

808

0.72

0.66

4.4

5.2

mmol/mol

39.7

39.1

0.19

762

(3024354) Oxygen [Partial pressure] in Venous blood

1.65

0.63

2.6

2.3

kpa

4.4

4.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.55

0.60

1.8

1.3

—

(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting

0.00

0.59

0.0

1.7

—

0.8

—

(40761536) Microorganisms panel - Urine sediment

1.57

0.59

5.0

3.7

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.52

0.59

1.1

1.0

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.52

0.59

1.5

1.9

g/l

2.7

1.9

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.71

0.58

8.3

3.6

mmol/l

22.1

25.4

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.66

0.56

3.2

2.4

g/l

134.7

128.1

—

(40761511) CBC panel - Blood by Automated count

913

1.68

0.55

14.7

10.6

—

(40761535) Cells panel - Urine sediment

1.50

0.55

3.7

3.5

—

(3022948) Iron [Moles/volume] in Serum or Plasma

107

0.63

0.52

3.4

2.5

umol/l

11.7

14.1

—

102

(3026008) Bacteria identified in Urine by Culture

286

1.28

0.51

2.4

2.5

—

(3013512) EKG study

237

0.76

0.46

3.2

3.3

—

(3022217) INR in Platelet poor plasma by Coagulation assay

1.46

0.45

27.8

15.2

—

1.2

—

(3000494) Fungus identified in Specimen by Culture

0.62

0.44

1.5

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

114

1.37

0.44

1.5

2.6

e6/l

6.9

4.7

—

(40760892) CBC W Ordered Manual Differential panel - Blood

214

0.75

0.43

5.4

5.9

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

102

0.66

0.42

3.1

1.7

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.54

0.42

2.6

2.8

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.54

0.42

3.6

2.2

1.2

—

(3000475) Leukocytes [#/volume] in Synovial fluid

0.00

0.41

0.0

1.6

—

4011.4

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.6

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.41

0.0

1.3

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.41

0.0

1.3

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

351

1.23

0.41

3.6

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.41

0.0

1.2

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.41

0.0

1.2

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.41

0.0

1.2

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.41

0.0

1.1

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.41

0.0

1.2

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.41

0.0

1.5

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.41

0.0

1.2

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.41

0.0

1.2

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

1.41

0.39

3.4

1.9

g/l

0.2

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.39

0.35

1.2

1.7

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

612

0.84

0.32

3.1

—

(4010399)

1.34

0.31

1.3

1.5

—

(3037467) Urinalysis macro (dipstick) panel - Urine

619

1.19

0.31

3.7

4.0

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.66

0.27

2.6

1.4

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

848

0.82

0.25

3.9

4.4

mmol/l

5.7

5.8

0.30

781

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

1.33

0.23

3.4

1.8

g/l

1.1

1.2

—

(40768793) Breast Pathology biopsy report

1.30

0.23

1.2

—

(3000330) Specific gravity of Urine by Test strip

1.26

0.23

2.8

2.7

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.21

0.0

1.2

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.21

0.0

4.6

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.9

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3044941) Cell count panel - Synovial fluid

0.00

0.21

0.0

1.5

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.21

0.0

1.1

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.21

0.0

1.4

—

(3021788) Differential panel - Synovial fluid

0.00

0.21

0.0

1.9

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.21

0.0

1.1

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.29

0.21

1.3

1.4

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.21

0.0

1.2

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

137

1.20

0.20

2.1

1.5

—

(3015736) pH of Urine

351

1.13

0.19

3.1

3.3

—

(3022621) pH of Urine by Test strip

1.22

0.18

2.9

2.5

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

196

1.16

0.18

3.0

2.9

ng/l

964.8

732.0

0.32

162

(3000492) Spirometry study

1.14

0.17

1.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

101

1.21

0.17

1.8

1.4

—

(3007164) IgA [Mass/volume] in Serum or Plasma

203

0.86

0.17

1.4

1.5

g/l

2.5

2.4

0.06

124

(36660697) Celiac disease serology panel - Serum

0.75

0.16

1.0

1.1

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.19

0.16

1.6

1.9

nmol/l

358.1

371.4

—

(3041096) Erythrocytes [Presence] in Urine by Automated

257

1.12

0.15

3.0

3.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

152

1.14

0.13

1.9

1.8

—

(3009542) Hematocrit [Volume Fraction] of Blood

811

1.13

0.13

17.6

12.4

36.9

39.7

1.49

625

(3022145) Colonoscopy Study observation

1.16

0.11

1.0

1.4

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

196

0.90

0.10

1.2

1.3

u/ml

3.2

11.1

—

(3025941) Bacteria identified in Stool by Culture

1.04

0.08

1.3

1.2

—

(3025159) Blasts/100 leukocytes in Blood

0.82

0.08

2.4

6.2

—

0.0

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

0.77

0.08

1.4

1.2

—

(1761868) Lipid panel - Serum or Plasma

324

1.07

0.08

2.6

2.7

—

(3019225) pH of Specimen

0.82

0.08

2.3

3.9

—

(3042936) Bacteria identified in Isolate by Culture

110

0.90

0.05

1.5

1.8

—

(3006315) Basophils [#/volume] in Blood

451

0.96

0.04

3.9

5.5

e9/l

0.0

0.47

401

(3013115) Eosinophils [#/volume] in Blood

470

0.96

0.03

3.9

5.6

e9/l

0.2

0.21

425

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

199

0.94

0.03

1.3

iu/ml

15.0

28.9

—

(3001604) Monocytes [#/volume] in Blood

449

0.96

0.02

3.9

5.4

e9/l

0.5

1.84

399

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

288

0.96

0.02

2.9

3.4

ng/l

12.2

21.6

2.17

180

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

104

1.06

0.01

5.2

5.8

—

(42870588) Differential panel, method unspecified - Blood

287

1.01

0.00

4.6

4.8

—

(3023368) Bacteria identified in Blood by Culture

175

0.97

0.00

9.5

3.6

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

1.9

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

1.9

—

106.3

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.2

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.0

1.1

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(4146454)

0.00

0.0

2.8

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

0.0

1.0

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

1.9

—

3.9

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.4

—

(3028433) Virus identified in Specimen by Culture

0.00

0.0

1.3

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

1.1

—

95.3

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

0.0

1.5

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.0

1.8

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.0

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

3.3

—

(3015183) Erythrocyte sedimentation rate

0.00

0.0

1.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3011436) Histone Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3004451) EKG impression Narrative

0.00

0.0

1.5

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.3

—

(3017732) Neutrophils [#/volume] in Blood

0.95

0.00

1.3

2.0

e9/l

4.4

3.9

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.9

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

19.5

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.00

0.00

1.0

2.5

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.89

0.00

2.1

1.8

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.0

2.4

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.2

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

12.0

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.1

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

0.0

1.0

—

(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.3

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

1.8

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

0.8

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

0.0

1.4

—

1.9

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.2

—

87.7

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3013293) Extractable nuclear Ab [Presence] in Serum

0.00

0.0

1.8

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.95

0.00

1.5

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

5.8

—

(4027681)

0.00

0.0

1.2

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3035880) pH of Pleural fluid

0.00

0.0

1.0

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.6

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3045788) Cell count panel - Pleural fluid

0.00

0.0

1.2

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

1.3

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: C3_OVARY_GRANULOSA – Granulosa cell carcinoma of ovary

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Granulosa cell carcinoma of ovary

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Case counts by code for Granulosa cell carcinoma of ovary (C3_OVARY_GRANULOSA)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints