Lichen planopilaris

L12_LICHENPLANO

obsolete_alopecia:

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L66.1 Cause of death: ICD-10 — L66.1 2 out of 7 registries used, show all original rules.	122
4. Check minimum number of events None	122
5. Include endpoints None	122
6. Filter based on genotype QC (FinnGen only)	116

Control definitions (FinnGen only)

Control exclude: L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L66
Name in latin: Lichen planopilaris

NAME	L12_LICHENPLANO
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L661
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L661
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Lichen planopilaris based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	618	485	131
Only index persons	608	481	127
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.00
Only index persons	0.02	0.02	0.00
Median age at first event (years)
Whole population	59.19	61.81	49.78
Only index persons	59.08	61.54	49.78

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	116	100	16
Unadjusted period prevalence (%)	0.03	0.04	0.01
Median age at first event (years)	62.52	63.82	54.35

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
122: Matched controls
1220

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L66.1

ICD-10 Finland

Lichen planopilaris

+∞

176.1

122

D07AD01

ATC

clobetasol; topical

35.5

83.9

132

TQX10

NOMESCO Finland

Biopsy of skin and subcutaneous tissue

26.4

72.0

P01BA02

ATC

hydroxychloroquine; oral

16.5

54.8

L30.9

ICD-10 Finland

Dermatitis, unspecified

6.3

22.6

144

D07AC01

ATC

betamethasone; topical

5.8

20.2

310

D07AC13

ATC

mometasone; topical

4.9

17.3

236

L43.8

ICD-10 Finland

Other lichen planus

37.1

15.3

D07XC01

ATC

betamethasone; topical

5.3

12.9

L66.9

ICD-10 Finland

Cicatricial alopecia, unspecified

+∞

11.6

D07AB02

ATC

hydrocortisone butyrate; topical

3.7

11.5

260

L43.9

ICD-10 Finland

Lichen planus, unspecified

14.8

11.1

L66.8

ICD-10 Finland

Other cicatricial alopecia

+∞

10.6

E0000UV, ,

ATC

3.4

9.9

382

J01AA04

ATC

lymecycline; systemic

4.2

9.7

H04.10

ICD-10 Finland

Dry eye syndrome

4.0

9.1

L63.9

ICD-10 Finland

Alopecia areata, unspecified

+∞

8.4

D05BB02

ATC

acitretin; oral

14.4

8.1

Z2221

NOMESCO Finland

Medical doctor

2.9

7.4

227

L93.0

ICD-10 Finland

Discoid lupus erythematosus

42.5

6.8

L21.8

ICD-10 Finland

Other seborrhoeic dermatitis

28.3

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768443) Skin Pathology biopsy report

15.33

39.78

1.4

1.2

—

(3037522) Nuclear Ab [Titer] in Serum

149

3.91

10.96

1.4

330.67

633.17

titre

0.93

(3000494) Fungus identified in Specimen by Culture

118

3.46

7.77

1.5

1.4

—

(3002256) Pathology report gross observation

119

3.43

7.66

1.6

1.2

—

(40768804) Tissue Pathology biopsy report

437

2.86

7.33

2.8

2.0

—

(3023420) DNA double strand Ab [Units/volume] in Serum

10.85

6.17

1.2

—

(3001604) Monocytes [#/volume] in Blood

511

2.64

6.08

6.2

5.2

0.52

0.54

e9/l

0.34

445

(3006315) Basophils [#/volume] in Blood

514

2.62

5.96

6.2

5.1

0.04

e9/l

0.10

448

(40760892) CBC W Ordered Manual Differential panel - Blood

473

2.52

5.73

6.4

5.6

—

(3019198) Lymphocytes [#/volume] in Blood

523

2.54

5.61

6.3

5.2

1.88

2.24

e9/l

0.79

472

(3013115) Eosinophils [#/volume] in Blood

527

2.50

5.46

6.3

5.2

0.17

0.18

e9/l

0.07

467

(3013650) Neutrophils [#/volume] in Blood by Automated count

596

2.41

4.75

8.6

8.5

3.19

3.87

e9/l

3.36

521

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

444

2.06

3.74

2.2

2.1

87.27

78.96

nmol/l

1.60

388

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.86

3.10

1.0

1.1

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

447

1.91

3.07

3.5

3.6

36.60

35.94

g/l

0.49

417

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

4.09

3.06

1.3

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

811

2.17

2.87

5.6

6.9

76.50

76.62

u/l

0.01

752

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

3.45

2.81

1.6

1.9

—

(3021589) Normoblasts [#/volume] in Blood

456

1.79

2.55

9.1

8.8

0.00

e9/l

0.62

366

(3019832) Treponema pallidum Ab [Presence] in Serum

2.53

2.50

2.1

1.6

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

262

1.85

2.49

1.3

1.2

0.65

1.66

u/ml

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

6.46

2.39

1.4

1.1

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

5.74

2.23

1.0

1.3

—

(3013707) Erythrocyte sedimentation rate by Westergren method

816

1.92

2.22

4.0

3.9

10.37

11.81

mm/h

0.65

732

(3001122) Ferritin [Mass/volume] in Serum or Plasma

416

1.69

2.14

3.1

2.4

134.67

99.87

ug/l

0.53

384

(3020717) Zinc [Moles/volume] in Serum or Plasma

5.16

2.09

1.0

11.84

20.03

umol/l

—

(3037467) Urinalysis macro (dipstick) panel - Urine

704

1.75

2.08

3.7

4.0

—

(40761536) Microorganisms panel - Urine sediment

2.27

2.02

2.3

3.4

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

414

1.65

1.96

1.9

1.8

93.88

98.60

pmol/l

0.27

191

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

0.00

1.94

0.0

1.9

—

1.21

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

370

1.65

1.91

2.7

2.8

2.35

2.36

mmol/l

0.23

322

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

836

1.78

1.80

4.8

4.3

14.29

14.79

pmol/l

1.48

760

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

460

1.60

1.77

4.0

4.5

1.23

1.22

mmol/l

0.81

413

(36304419) Bacteria [Presence] in Urine

260

1.67

1.76

2.9

2.7

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

331

1.63

1.75

3.1

2.7

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

1.75

0.0

2.3

—

46.36

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

110

989

2.14

1.74

13.5

11.4

83.30

80.98

ml/min/173m2

0.66

101

799

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

0.00

1.73

0.0

1.9

—

0.74

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

1.73

0.0

1.9

—

25.11

—

(40758558) Short blood count panel - Blood

271

1.65

1.70

5.1

6.8

—

(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma

3.68

1.63

3.0

3.3

—

22.38

—

(1002224) Polysomnography panel

2.60

1.63

1.1

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

498

1.55

1.57

4.7

5.7

1.23

1.22

mmol/l

0.28

429

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

3.43

1.54

2.4

1.5

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

109

987

1.98

1.53

5.9

5.1

1.74

3.07

mu/l

0.56

104

904

(3019550) Sodium [Moles/volume] in Serum or Plasma

116

1081

2.48

1.51

12.4

13.6

139.83

139.90

mmol/l

0.16

111

1051

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.81

1.45

2.8

1.9

—

(3030467) Casts [#/volume] in Urine by Automated count

266

1.56

1.38

3.0

2.8

0.29

0.51

e6/l

0.61

193

(3004616) Nuclear Ab [Presence] in Serum

3.02

1.37

1.8

1.2

—

(3031040) Bacteria [#/volume] in Urine by Automated count

672

1.50

1.30

3.5

4.0

—

8213.09

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

1.96

1.29

1.2

1.4

—

31.29

—

(3007164) IgA [Mass/volume] in Serum or Plasma

226

1.56

1.28

1.5

1.4

2.14

2.30

g/l

0.22

125

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

209

1.58

1.27

2.0

2.20

3.18

mg/l

2.06

181

(3002582) Erythrocytes [#/volume] in Urine

289

1.51

1.26

2.9

2.8

15.83

45.48

e6/l

0.80

216

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.37

1.20

2.7

2.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

239

1.52

1.18

1.8

2.0

—

(3044889) 12 lead EKG panel

762

1.49

1.18

3.2

3.5

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

146

1.62

1.13

2.0

2.7

6.60

3.27

e6/l

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

112

1043

1.90

1.13

10.7

11.9

21.91

21.37

mg/l

0.06

786

(3052851) Hemolysis interference index of Serum or Plasma

2.33

1.12

2.1

—

(3018095) Leukocytes [#/volume] in Urine

353

1.44

1.08

3.0

3.3

20.65

70.01

e6/l

1.82

235

(3044640) Blood type and Crossmatch panel - Blood

307

1.45

1.07

1.9

2.0

—

(3008898) HLA-B27 [Presence]

2.12

1.04

1.1

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.33

1.04

1.2

1.1

—

(3007853) Bacteria identified in Skin by Aerobe culture

100

1.69

1.03

1.6

—

(4035726) Immunohistochemistry procedure

100

1.69

1.03

1.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

101

1.67

0.99

1.5

—

(3000850) Epithelial cells [#/volume] in Urine

195

1.49

0.97

2.7

2.3

6.60

5.89

e6/l

0.10

177

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

162

1.52

0.93

2.2

2.5

0.74

1.12

e6/l

0.44

(36660697) Celiac disease serology panel - Serum

1.69

0.92

1.3

1.1

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

106

985

1.58

0.91

5.0

5.4

38.51

39.02

mmol/mol

0.31

101

911

(3004588) Protein electrophoresis panel - Serum or Plasma

1.86

0.91

2.6

2.2

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

129

1.56

0.90

1.7

1.9

28.16

23.28

0.61

111

(3021960) Folate [Moles/volume] in Serum or Plasma

225

1.44

0.90

1.4

1.5

24.76

21.16

nmol/l

0.59

183

(3020564) Creatinine [Moles/volume] in Serum or Plasma

116

1105

2.01

0.88

16.1

14.3

69.09

70.42

umol/l

0.29

116

1105

(3018418) pH of Serum or Plasma

320

1.37

0.83

2.5

3.2

7.39

7.40

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

672

1.35

0.82

2.5

3.0

46.88

45.80

u/l

0.03

630

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

212

1.42

0.80

1.3

1.34

12.36

u/ml

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

390

0.72

0.78

2.8

3.2

26.68

22.33

ng/l

0.17

259

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

100

1.57

0.77

1.7

1.6

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

223

1.39

0.76

1.8

1.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.73

0.74

1.3

1.4

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.84

0.74

1.1

1.3

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.84

0.74

2.4

1.1

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

217

1.38

0.70

1.4

1.3

13.42

37.63

iu/ml

1.91

(40761511) CBC panel - Blood by Automated count

114

1091

1.68

0.68

10.5

11.2

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

192

1.38

0.66

3.6

3.4

13.82

177.48

ng/l

1.08

146

(3026008) Bacteria identified in Urine by Culture

322

1.31

0.65

2.6

2.7

—

(3049717) Cytology report of Urine Cyto stain

1.75

0.64

1.2

2.8

—

(3019225) pH of Specimen

1.53

0.63

2.2

4.2

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

1.69

0.62

1.0

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

1.69

0.62

1.0

1.2

—

(4094501) Cardiovascular stress test using bicycle ergometer

1.69

0.62

1.0

1.1

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.60

0.0

2.0

—

6.87

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.60

0.0

2.0

—

1.45

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

261

1.31

0.58

1.7

2.9

237.70

884.45

ng/l

4.85

220

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

0.59

0.54

1.5

2.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

100

0.58

0.54

1.5

1.9

—

(40768797) Stomach Pathology biopsy report

157

1.33

0.47

1.5

1.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

194

1.30

0.46

1.5

—

(3026782) Osmolality of Urine

176

1.30

0.46

2.9

2.5

552.50

510.93

mosm/kgh2o

0.64

152

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

122

1.36

0.45

1.3

1.5

—

(1761868) Lipid panel - Serum or Plasma

366

1.23

0.44

2.6

2.9

—

(42529406) Shigella sp [Presence] in Stool by Culture

1.64

0.43

1.0

1.3

—

(3000570) Elastase.pancreatic [Mass/mass] in Stool

1.59

0.43

1.0

1.2

—

295.20

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

216

1.26

0.41

2.1

1.7

0.91

0.87

mg/l

0.06

173

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.41

0.0

1.5

—

3.88

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.41

0.0

1.5

—

107.94

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.41

0.0

1.5

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.41

0.0

1.1

—

(3013512) EKG study

311

1.22

0.41

2.7

3.3

—

(3024928) Oxygen saturation in Venous blood

0.00

0.41

0.0

2.4

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.40

0.0

1.4

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.40

0.0

1.4

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.39

0.0

1.3

—

2.81

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.39

0.0

1.1

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

107

1.35

0.39

8.9

5.6

104.86

104.23

mmol/l

0.25

107

(3022621) pH of Urine by Test strip

0.64

0.37

1.2

2.5

—

(40761535) Cells panel - Urine sediment

0.63

0.37

3.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

143

0.75

0.34

1.4

1.9

—

(3012516) Albumin [Mass/volume] in Urine

289

1.19

0.33

3.1

2.9

41.21

299.21

mg/l

0.50

160

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

104

1003

1.25

0.32

4.7

3.9

1.21

1.24

mmol/l

0.23

917

(3011397) Hemoglobin [Presence] in Urine by Test strip

232

1.21

0.32

2.0

3.5

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

108

1046

1.28

0.32

4.9

4.5

5.73

5.85

mmol/l

0.54

102

957

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

574

1.16

0.32

4.1

5.6

9.49

10.15

umol/l

0.45

545

(3001019) Free T4 and TSH panel - Serum or Plasma

1.34

0.31

1.7

1.8

—

(3035350) Ketones [Presence] in Urine by Test strip

505

1.16

0.31

2.6

3.5

0.00

0.01

estimate

0.49

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.26

0.30

1.1

1.4

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

110

1070

1.29

0.29

5.5

5.1

2.83

mmol/l

0.02

105

986

(3021601) Nitrite [Presence] in Urine by Test strip

509

1.15

0.27

3.4

4.9

0.00

estimate

-0.00

(3013139) Helicobacter pylori Ag [Presence] in Stool

0.67

0.27

1.2

1.3

—

(3023368) Bacteria identified in Blood by Culture

232

0.84

0.25

4.4

3.9

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

631

1.14

0.25

2.7

2.8

—

(3000492) Spirometry study

0.73

0.25

1.8

1.5

—

(3009508) Creatinine [Moles/volume] in Urine

306

1.15

0.24

3.0

2.8

6.85

7.16

mmol/l

0.14

252

(3009445) Proteinase 3 Ab [Units/volume] in Serum

1.33

0.23

1.6

1.5

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.33

0.23

1.8

1.5

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

1.26

0.22

16.0

6.4

26.20

24.60

mmol/l

—

(3026493) Urate [Moles/volume] in Serum or Plasma

250

1.16

0.22

2.5

2.3

15666.81

9658.29

umol/l

0.15

210

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.21

0.0

1.4

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.0

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.21

0.0

1.4

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

3.1

—

4.31

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.21

0.0

1.5

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(4146454) Self-monitoring of blood glucose

0.00

0.21

0.0

4.1

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.0

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.6

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.21

0.0

1.0

—

32.50

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

1.3

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.21

0.0

1.0

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.21

0.0

3.6

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.21

0.0

2.4

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3000012) Reticulocyte production index

0.00

0.21

0.0

1.1

—

(3015736) pH of Urine

397

1.13

0.21

2.2

3.3

5.75

5.71

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

2.8

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.21

0.0

1.3

—

(3009261) Glucose [Presence] in Urine by Test strip

516

1.12

0.21

2.6

3.5

0.00

estimate

-0.00

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.21

0.0

3.5

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

107

1045

1.19

0.20

4.9

4.4

1.57

1.58

mmol/l

0.10

100

962

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.24

0.20

1.3

1.2

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.20

0.0

1.7

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

0.20

0.0

2.1

—

54.41

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.20

0.0

1.1

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.19

0.19

1.2

1.3

—

(3000991) Gas panel - Venous blood

0.72

0.17

20.0

5.2

—

(3022217) INR in Platelet poor plasma by Coagulation assay

461

1.11

0.17

17.1

9.5

1.24

1.17

inr

0.18

138

(3041096) Erythrocytes [Presence] in Urine by Automated

284

1.12

0.17

2.9

3.1

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.19

0.17

3.8

1.8

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

140

1.16

0.16

2.6

1.7

—

(3048689) Calprotectin [Mass/mass] in Stool

131

1.17

0.15

1.5

1.8

112.00

126.01

ug/g

—

107

(3020682) Albumin/Creatinine [Ratio] in Urine

306

1.11

0.15

3.4

15.05

7.91

mg/mmol

0.28

164

(3045414) Leukocytes [Presence] in Urine

1.12

0.10

1.2

1.6

—

(40768793) Breast Pathology biopsy report

1.12

0.10

1.6

1.3

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

107

1055

1.12

0.09

5.3

4.5

4.77

4.83

mmol/l

0.27

102

981

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.04

0.09

2.8

7.0

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

491

1.07

0.09

2.3

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.10

0.09

2.7

2.1

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.05

0.08

1.4

1.5

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

0.80

0.08

1.5

2.6

1.57

4.55

ug/l

—

(4200892) Spirometry reversibility

1.09

0.07

1.1

1.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.06

0.07

4.5

1.9

—

(3025159) Blasts/100 leukocytes in Blood

1.04

0.07

3.9

5.4

—

0.04

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.02

0.07

1.0

1.4

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.86

0.07

2.0

3.0

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.12

0.06

1.9

1.7

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

100

1.11

0.05

5.2

3.7

0.93

1.05

mmol/l

1.15

(3022145) Colonoscopy Study observation

120

0.91

0.05

1.3

—

(3003694) ABO and Rh group [Type] in Blood

270

0.95

0.03

1.3

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

124

0.96

0.00

3.6

6.0

—

(3042936) Bacteria identified in Isolate by Culture

141

0.99

0.00

1.2

1.9

—

(3029937) Albumin [Presence] in Urine by Test strip

269

1.00

0.00

3.6

3.5

0.00

estimate

-0.00

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

108

1.02

0.00

2.3

4.4

4.15

1.94

ug/l

0.39

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

396

1.02

0.00

3.1

3.5

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

0.98

0.00

18.2

6.0

0.90

1.39

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

0.98

0.00

18.2

5.9

0.56

0.67

—

(21494755) Public health laboratory ask at order entry panel

0.99

0.00

1.2

1.4

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

-0.00

0.0

3.6

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.5

—

18.49

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(40763324) Parainfluenza virus 1 RNA [Presence] in Isolate by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

-0.00

0.0

1.3

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.5

—

28.50

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.8

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

3.0

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.4

—

(3002619) Bacteria identified in Specimen by Culture

0.00

-0.00

0.0

1.2

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.02

-0.00

18.2

6.2

96.00

94.55

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

2.1

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

5.82

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.00

-0.00

2.0

4.7

24.34

24.74

mmol/l

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.0

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.96

-0.00

2.0

1.4

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

10.0

—

0.65

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.0

—

(40763470) Parainfluenza virus 4 RNA [Presence] in Isolate by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3039429) Cortisol [Moles/volume] in Saliva (oral fluid)

0.00

-0.00

0.0

2.2

—

32.84

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.3

—

6.13

—

(3012441) Differential panel - Pleural fluid

0.00

-0.00

0.0

1.3

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.4

—

(42868417) European tick borne encephalitis virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(42868766) Dientamoeba fragilis DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.6

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

71.58

—

(3016244) Insulin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.4

—

9.32

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

2.0

—

11.89

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.1

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.4

—

194.20

—

(37020300) Entamoeba histolytica DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.4

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3025941) Bacteria identified in Stool by Culture

1.02

-0.00

1.0

1.1

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

-0.00

0.0

1.3

—

29.85

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.4

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

3.0

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

-0.00

0.0

1.2

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.4

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.4

—

(3035062) Alkaline phosphatase.liver 1 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

53.60

—

(3036180) Methadone [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

-0.00

0.0

1.5

—

32.08

—

(40768800) Prostate Pathology biopsy report

0.00

-0.00

0.0

1.2

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

0.97

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

4.8

—

130.33

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

1.63

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

-0.00

0.0

1.5

—

42.55

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.4

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

3.0

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

1.8

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.3

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3006653) Thiamine [Moles/volume] in Blood

0.00

-0.00

0.0

1.9

—

115.14

—

(3036185) Alkaline phosphatase.liver 2 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

10.80

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.2

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

1.2

—

(3020911) Cortisol [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.3

—

51.57

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_LICHENPLANO and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_LICHENPLANO.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_LICHENPLANO – Lichen planopilaris

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Lichen planopilaris

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints