Lichen planopilaris

L12_LICHENPLANO

obsolete_alopecia:

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L66.1 Cause of death: ICD-10 — L66.1 2 out of 7 registries used, show all original rules.	103
4. Check minimum number of events None	103
5. Include endpoints None	103
6. Filter based on genotype QC (FinnGen only)	103

Control definitions (FinnGen only)

Control exclude: L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L66
Name in latin: Lichen planopilaris

NAME	L12_LICHENPLANO
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L661
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L661
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Lichen planopilaris based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	618	485	131
Only index persons	608	481	127
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.00
Only index persons	0.02	0.02	0.00
Median age at first event (years)
Whole population	59.19	61.81	49.78
Only index persons	59.08	61.54	49.78

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	103	86	17
Unadjusted period prevalence (%)	0.03	0.03	0.01
Median age at first event (years)	60.01	61.15	54.24

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
86: Matched controls
858

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L66.1

ICD-10 Finland

Lichen planopilaris

+∞

121.9

D07AD01

ATC

clobetasol; topical

29.5

40.3

TQX10

NOMESCO Finland

Biopsy of skin and subcutaneous tissue

23.4

30.0

P01BA02

ATC

hydroxychloroquine; oral

19.7

27.5

L43.8

ICD-10 Finland

Other lichen planus

41.7

14.1

L43.9

ICD-10 Finland

Lichen planus, unspecified

59.7

13.3

D07AC01

ATC

betamethasone; topical

5.6

12.7

215

L30.9

ICD-10 Finland

Dermatitis, unspecified

5.9

10.8

D07AC13

ATC

mometasone; topical

5.0

10.8

155

D07AB02

ATC

hydrocortisone butyrate; topical

4.9

10.7

156

D05BB02

ATC

acitretin; oral

34.4

9.7

L66.8

ICD-10 Finland

Other cicatricial alopecia

+∞

8.5

L66.9

ICD-10 Finland

Cicatricial alopecia, unspecified

+∞

7.4

J01AA04

ATC

lymecycline; systemic

5.2

7.2

D07XC01

ATC

betamethasone, combinations; topical

4.5

6.4

L71.8

ICD-10 Finland

Other rosacea

+∞

6.3

XQ848

NOMESCO Finland

Dermatological photography

13.9

6.3

L57.0

ICD-10 Finland

Actinic keratosis

6.3

6.2

E0000UV

ATC

3.2

6.2

253

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768443) Skin Pathology biopsy report

17.77

37.00

1.5

1.1

—

(3037522) Nuclear Ab [Titer] in Serum

124

4.10

10.01

1.5

1.4

344.6

560.0

titre

0.66

(3023420) DNA double strand Ab [Units/volume] in Serum

13.66

6.22

1.2

1.1

—

(3001604) Monocytes [#/volume] in Blood

435

2.90

6.03

6.6

5.2

0.5

e9/l

0.29

380

(3006315) Basophils [#/volume] in Blood

437

2.88

5.94

6.7

5.2

0.0

e9/l

0.53

381

(3019198) Lymphocytes [#/volume] in Blood

445

2.79

5.60

6.7

5.2

1.9

2.2

e9/l

0.63

396

(40768804) Tissue Pathology biopsy report

363

2.67

5.56

2.8

1.9

—

(3013115) Eosinophils [#/volume] in Blood

449

2.74

5.44

6.9

5.3

0.2

e9/l

0.38

400

(3000494) Fungus identified in Specimen by Culture

101

3.11

5.31

1.5

1.4

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

506

2.77

5.13

9.3

8.8

3.2

3.9

e9/l

2.67

442

(42870588) Differential panel, method unspecified - Blood

270

2.55

5.13

6.5

5.2

—

(3002256) Pathology report gross observation

100

2.83

4.29

1.7

1.2

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

369

2.05

3.18

2.3

2.2

86.7

79.3

nmol/l

1.34

323

(3021589) Normoblasts [#/volume] in Blood

382

2.02

3.06

9.7

8.9

0.0

e9/l

0.62

307

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

3.47

2.85

1.8

2.0

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

377

1.91

2.64

3.8

3.7

36.2

35.9

g/l

0.12

353

(3020717) Zinc [Moles/volume] in Serum or Plasma

7.43

2.57

1.0

11.8

22.8

umol/l

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.77

2.56

1.0

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

3.85

2.42

1.4

1.3

—

(3013707) Erythrocyte sedimentation rate by Westergren method

696

2.12

2.30

4.1

4.0

10.6

11.9

mm/h

0.51

628

(40758558) Short blood count panel - Blood

220

1.90

2.29

5.5

7.2

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

698

2.10

2.26

5.8

7.1

74.7

76.9

u/l

0.19

648

(1002224) Polysomnography panel

3.25

2.06

1.1

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

346

1.73

1.95

1.9

1.8

96.3

98.5

pmol/l

0.11

160

(3019832) Treponema pallidum Ab [Presence] in Serum

2.45

1.77

2.5

1.7

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

0.00

1.76

0.0

1.9

—

1.2

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

3.98

1.73

2.4

1.5

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

221

1.73

1.70

1.3

1.2

0.7

1.6

u/ml

—

(40761536) Microorganisms panel - Urine sediment

2.29

1.68

2.7

3.7

—

(3037467) Urinalysis macro (dipstick) panel - Urine

594

1.70

1.67

3.8

4.1

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

1.56

0.0

2.0

—

25.3

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

0.00

1.55

0.0

1.9

—

0.8

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

910

2.58

1.49

12.7

14.2

139.8

139.9

mmol/l

0.21

887

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

341

0.58

1.47

3.3

3.2

26.0

23.5

ng/l

0.07

225

(3015377) Calcium [Moles/volume] in Serum or Plasma

311

1.59

1.45

3.0

2.8

2.3

2.4

mmol/l

0.18

271

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

388

1.56

1.40

4.3

4.8

1.2

mmol/l

0.73

349

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

704

1.70

1.39

5.0

4.2

14.2

14.9

pmol/l

2.02

643

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

1.36

0.0

2.3

—

47.8

—

(4035726)

1.92

1.36

1.3

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

832

1.99

1.34

14.5

11.6

84.0

80.1

ml/min/173m2

1.26

665

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

424

1.51

1.25

4.9

6.1

1.2

mmol/l

0.31

365

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

177

1.63

1.24

1.3

1.2

1.3

8.5

u/ml

—

(3052851) Hemolysis interference index of Serum or Plasma

2.39

1.20

1.8

2.2

—

(3022217) INR in Platelet poor plasma by Coagulation assay

1.82

1.19

31.9

18.2

1.4

inr

—

(3007164) IgA [Mass/volume] in Serum or Plasma

197

1.58

1.17

1.5

1.3

2.2

2.3

g/l

0.21

113

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

181

1.58

1.13

1.3

1.2

14.3

34.9

iu/ml

1.62

(3044889) 12 lead EKG panel

643

1.54

1.13

3.1

3.4

—

(3008898) HLA-B27 [Presence]

2.27

1.10

1.1

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

175

1.57

1.06

2.1

2.0

2.1

3.0

mg/l

2.03

151

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

836

1.76

1.02

6.0

5.0

1.8

3.3

mu/l

0.55

765

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

1.87

0.98

1.3

1.4

—

31.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

179

1.52

0.96

1.8

1.5

—

(3009542) Hematocrit [Volume Fraction] of Blood

794

1.62

0.95

15.5

13.3

40.3

40.0

0.25

583

(3031040) Bacteria [#/volume] in Urine by Automated count

571

1.43

0.94

3.5

4.1

—

8213.1

—

(3020961) Endomysium IgA Ab [Titer] in Serum

1.93

0.90

1.0

1.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

884

1.72

0.87

11.4

12.3

21.3

21.1

mg/l

0.02

674

(3020564) Creatinine [Moles/volume] in Serum or Plasma

932

2.06

0.83

16.8

14.8

69.1

71.3

umol/l

0.47

932

(36304419) Bacteria [Presence] in Urine

221

1.43

0.82

3.4

2.6

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.72

0.81

1.4

1.5

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

108

1.57

0.79

1.8

2.0

27.9

22.6

0.70

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.61

0.73

1.6

1.5

—

(36660697) Celiac disease serology panel - Serum

1.67

0.71

1.3

1.1

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

1.97

0.71

1.0

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

1.97

0.71

1.0

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

1.97

0.71

1.0

1.2

—

(3002582) Erythrocytes [#/volume] in Urine

249

1.35

0.64

3.3

2.8

16.7

51.5

e6/l

0.78

181

(3004588) Protein electrophoresis panel - Serum or Plasma

1.65

0.63

3.0

2.0

—

(3044640) Blood type and Crossmatch panel - Blood

250

1.34

0.63

1.7

2.0

—

(3019225) pH of Specimen

1.59

0.62

2.1

4.8

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.71

0.58

2.7

1.1

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.49

0.56

1.7

1.5

—

(3018095) Leukocytes [#/volume] in Urine

302

1.30

0.55

3.4

18.2

59.2

e6/l

1.56

197

(3030467) Casts [#/volume] in Urine by Automated count

227

1.32

0.54

3.5

2.8

0.4

0.5

e6/l

0.28

159

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

284

1.29

0.54

3.3

2.7

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

191

1.33

0.53

1.7

2.1

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

128

1.39

0.52

2.3

2.6

7.0

3.4

e6/l

—

(40761511) CBC panel - Blood by Automated count

921

1.62

0.52

10.4

11.4

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

832

1.40

0.51

4.9

5.4

38.6

39.1

mmol/mol

0.30

771

(40768797) Stomach Pathology biopsy report

129

1.38

0.50

1.5

1.2

—

(1761868) Lipid panel - Serum or Plasma

306

1.27

0.49

2.7

3.0

—

(3026782) Osmolality of Urine

139

1.36

0.48

3.2

2.5

524.9

522.8

mosm/kgh2o

0.02

120

(3013512) EKG study

261

1.27

0.46

2.7

3.3

—

(3018418) pH of Serum or Plasma

271

1.26

0.45

2.3

3.3

7.4

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.64

0.43

1.8

1.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

197

1.28

0.43

5.5

4.8

—

(3024928) Oxygen saturation in Venous blood

0.00

0.41

0.0

2.8

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.41

0.0

1.1

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.41

0.0

2.1

—

1.4

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.41

0.0

1.4

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.41

0.0

2.1

—

6.9

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.41

0.0

1.4

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.41

0.0

1.4

—

(3000850) Epithelial cells [#/volume] in Urine

162

1.29

0.39

3.2

2.3

7.3

5.6

e6/l

0.21

146

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.41

0.38

1.0

1.3

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

896

1.39

0.38

5.5

5.1

2.8

mmol/l

0.21

824

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

842

1.31

0.37

4.8

4.0

1.2

1.3

mmol/l

0.29

770

(3001019) Free T4 and TSH panel - Serum or Plasma

1.42

0.35

1.8

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.42

0.35

1.2

1.3

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

575

1.20

0.34

2.5

3.0

50.5

47.5

u/l

0.06

543

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.35

0.34

1.3

1.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.37

0.32

3.7

1.9

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

168

1.24

0.30

3.9

3.5

15.4

198.6

ng/l

1.07

129

(3029937) Albumin [Presence] in Urine by Test strip

235

0.82

0.30

4.0

3.7

0.0

estimate

0.00

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.33

0.29

1.4

1.6

—

(4010399)

1.31

0.29

1.1

1.3

—

(3021440) Promyelocytes/100 leukocytes in Blood

1.23

0.27

3.6

5.8

—

0.0

—

(3000492) Spirometry study

0.67

0.27

2.0

1.5

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

0.67

0.27

17.8

4.4

1.1

1.3

mmol/l

—

(3026493) Urate [Moles/volume] in Serum or Plasma

218

1.19

0.26

2.6

2.4

17289.9

10978.5

umol/l

0.14

184

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.73

0.25

2.0

3.1

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

0.70

0.25

1.5

2.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

0.69

0.25

1.5

2.0

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

191

1.19

0.24

2.3

1.7

0.9

mg/l

0.04

151

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

153

1.21

0.24

1.4

1.5

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.26

0.23

2.0

1.6

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

342

0.87

0.22

3.3

3.7

—

(3012516) Albumin [Mass/volume] in Urine

241

1.16

0.22

3.1

2.8

45.5

349.4

mg/l

0.49

134

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

875

1.23

0.22

5.0

4.6

5.7

5.9

mmol/l

1.41

802

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.20

0.22

2.0

5.3

24.3

24.7

mmol/l

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.21

0.0

1.4

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.21

0.0

1.3

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.21

0.0

3.6

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.21

0.0

2.4

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.21

0.0

1.0

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.21

0.0

1.5

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

3.0

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.6

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.21

0.0

1.8

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.21

0.0

3.7

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.21

0.0

1.7

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.2

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.21

0.0

1.8

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

0.21

0.0

2.2

—

56.8

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.24

0.20

1.4

1.5

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.24

0.20

1.2

1.4

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.20

0.0

1.6

—

108.2

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.20

0.0

1.6

—

4.0

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.20

0.0

1.6

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.20

0.0

1.4

—

2.8

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.21

0.20

2.7

2.1

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.26

0.19

1.9

1.7

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

877

1.21

0.19

5.0

4.5

1.6

mmol/l

0.03

806

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.22

0.18

4.6

2.0

—

(3009508) Creatinine [Moles/volume] in Urine

254

1.14

0.18

2.9

2.7

7.0

7.5

mmol/l

0.17

208

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

235

1.14

0.18

1.8

3.0

271.6

903.4

ng/l

4.06

196

(3002179) Metamyelocytes/100 leukocytes in Blood

1.21

0.17

3.6

5.4

—

0.4

—

(3017181) Myelocytes/100 leukocytes in Blood

1.12

0.16

3.6

5.4

—

0.6

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

141

1.16

0.15

2.5

0.6

1.0

e6/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

113

1.17

0.14

2.5

1.7

—

(3032080) INR in Blood by Coagulation assay

340

0.91

0.11

9.5

6.3

1.2

inr

—

105

(3042936) Bacteria identified in Isolate by Culture

115

0.86

0.11

1.2

1.9

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

884

1.14

0.11

5.4

4.5

4.8

mmol/l

0.22

819

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

409

0.93

0.10

3.3

3.6

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.14

0.10

2.8

7.5

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

531

1.08

0.10

2.6

2.8

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.12

0.10

18.2

6.5

96.0

94.7

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

204

1.10

0.09

1.7

3.5

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.07

0.09

18.2

6.1

0.9

1.4

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.07

0.09

18.2

6.1

0.6

0.7

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.14

0.09

1.3

1.5

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

0.82

0.08

1.2

1.4

—

(3000991) Gas panel - Venous blood

0.82

0.08

20.0

5.6

—

(3025159) Blasts/100 leukocytes in Blood

1.08

0.08

4.0

5.6

—

0.0

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.08

0.08

1.0

1.5

—

(3015736) pH of Urine

336

0.93

0.08

2.2

3.4

—

(3041096) Erythrocytes [Presence] in Urine by Automated

245

1.08

0.08

3.2

3.3

—

(21494755) Public health laboratory ask at order entry panel

0.87

0.07

1.3

1.4

—

(3020682) Albumin/Creatinine [Ratio] in Urine

256

1.07

0.07

3.4

15.9

6.9

mg/mmol

0.35

139

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.02

0.07

5.6

3.9

0.9

1.1

mmol/l

—

(3022145) Colonoscopy Study observation

103

0.86

0.06

1.2

1.3

—

(3035350) Ketones [Presence] in Urine by Test strip

436

1.06

0.06

2.7

3.6

0.0

estimate

0.00

(3021601) Nitrite [Presence] in Urine by Test strip

437

1.05

0.05

3.6

5.1

0.0

estimate

0.00

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

118

0.92

0.03

1.4

2.0

—

(3009261) Glucose [Presence] in Urine by Test strip

443

1.03

0.01

2.7

3.6

0.0

estimate

0.00

(3003694) ABO and Rh group [Type] in Blood

224

1.03

0.00

1.3

—

(3023368) Bacteria identified in Blood by Culture

198

1.01

0.00

4.5

4.1

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

104

0.96

0.00

3.9

6.4

—

(3026008) Bacteria identified in Urine by Culture

276

1.02

0.00

2.8

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

109

1.01

0.00

2.3

4.3

4.2

1.9

ug/l

0.40

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.4

—

(40768800) Prostate Pathology biopsy report

0.00

0.0

1.2

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

(42868417) European tick borne encephalitis virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.2

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.0

1.2

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.0

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.4

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.4

—

(3006653) Thiamine [Moles/volume] in Blood

0.00

0.0

1.0

—

110.8

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

0.0

5.6

—

147.8

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

0.0

3.6

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.0

3.0

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

3.9

—

4.8

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.0

1.2

—

(44790048)

0.00

0.0

1.5

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

1.0

—

32.6

—

(42868766) Dientamoeba fragilis DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

1.4

—

(3028433) Virus identified in Specimen by Culture

0.00

0.0

1.3

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(44790047)

0.00

0.0

1.5

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

0.0

1.3

—

29.8

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

0.0

1.0

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

3.0

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

0.0

1.3

—

6.1

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.0

1.4

—

(3015076) Soybean IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

0.0

1.5

—

32.1

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.2

—

5.8

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.3

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.3

—

(44806118)

0.00

0.0

1.5

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.0

1.4

—

(3011648) Oxygen content in Venous blood

0.00

0.0

2.0

—

11.9

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.0

3.0

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

10.0

—

0.7

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.4

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

1.4

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

20.1

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.8

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.1

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.4

—

(4146454)

0.00

0.0

4.0

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.4

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.4

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.2

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.0

1.2

—

(3045788) Cell count panel - Pleural fluid

0.00

0.0

1.2

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

0.0

1.0

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

0.92

0.00

1.5

2.8

1.6

4.4

ug/l

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.0

2.3

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.3

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.2

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.6

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

1.0

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.0

1.0

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.0

1.4

—

(3012441) Differential panel - Pleural fluid

0.00

0.0

1.3

—

(37020300) Entamoeba histolytica DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.0

1.1

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(44790049)

0.00

0.0

1.5

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.0

1.6

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

0.0

1.4

—

194.2

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

1.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_LICHENPLANO and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_LICHENPLANO.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_LICHENPLANO – Lichen planopilaris

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Lichen planopilaris

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints