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Use of rotigotine

PDMED_ROTIGOTINE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC N04BC09

1 out of 7 registries used, show all original rules.

376

4. Check minimum number of events

Min. number of events 3
376

5. Include endpoints

None

376

6. Filter based on genotype QC (FinnGen only)

376

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 376 212 164
Unadjusted period prevalence (%) 0.07 0.07 0.07
Median age at first event (years) 64.25 63.53 65.18

-FinnGen-

Age distribution of first events

01040506070800102030405060708090100110120AgeIndividuals

-FinnGen-

Year distribution of first events

197019751980198519901995200020052010201520202023020406080100120140160YearIndividuals

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
323
Matched controls
3228
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N04BC09
ATC
rotigotine; transdermal
+∞
323.0
323
*
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
359.1
277.6
250
30
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
303.8
277.4
255
39
G20
ICD-10 Finland
Parkinson disease
303.7
271.3
249
35
N04BD01
ATC
selegiline; oral
415.3
209.3
190
11
N04BC04
ATC
ropinirole; oral
348.3
190.3
176
11
N04BC05
ATC
pramipexole; oral
55.3
181.9
228
134
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
446.1
174.3
160
7
N04BD02
ATC
rasagiline; oral
271.0
155.3
148
10
193
Kela drug reimbursment
Rasagiline
312.8
137.7
131
7
N87
ICPC
Parkinsonism
129.7
123.4
127
16
AAG20
NOMESCO Finland
Stereotactic intracranial implantation of electrodes
558.0
49.8
48
*
N03AE01
ATC
clonazepam; systemic
12.8
49.8
94
100
N04BX02
ATC
entacapone; oral
120.3
39.8
42
*
N04BB01
ATC
amantadine; oral
30.5
33.9
45
17
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
130.4
33.4
35
*
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
122.1
31.3
33
*
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
36.7
30.8
39
12
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
18.8
30.4
47
29
R25.1
ICD-10 Finland
Tremor, unspecified
16.4
29.5
48
34
N03AX12
ATC
gabapentin; oral
4.8
27.7
108
305
AA1AD
NOMESCO Finland
CT of head and brain
4.0
27.2
140
515
N04AA02
ATC
biperiden; systemic
18.4
27.1
42
26
N06DA03
ATC
rivastigmine; oral, transdermal
10.0
23.0
47
54
N05AH04
ATC
quetiapine; oral
4.3
22.6
97
294
G04BD12
ATC
mirabegron; oral
5.0
21.5
76
188
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
82.4
21.0
23
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.2
20.8
89
266
XA800
NOMESCO Finland
Neuropsychological investigation
9.1
19.2
41
51
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.4
18.5
59
129
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
47.0
18.5
22
5
L28
ICPC
Limited function/disability (L)
3.7
18.3
95
330
N06AX11
ATC
mirtazapine; oral
3.0
18.1
149
725
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.0
17.8
141
667
SPAT1231
SPAT
Assessment of adjustments needed in living environment
14.4
17.3
29
22
C07AA05
ATC
propranolol; systemic
3.3
16.8
101
392
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
5.3
16.7
53
115
SPAT1229
SPAT
Assessment of need for aid
4.6
16.4
60
152
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.1
15.5
51
115
N03AX16
ATC
pregabalin; oral
2.9
14.9
114
515
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
8.1
14.3
32
43
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.6
13.9
50
124
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.0
13.5
88
354
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
4.5
13.4
49
123
R53
ICD-10 Finland
Malaise and fatigue
2.8
13.2
100
441
R47.1
ICD-10 Finland
Dysarthria and anarthria
23.7
13.0
18
8
N19
ICPC
Speech disorder
18.2
12.7
19
11
A28
ICPC
Limited function/disability NOS
3.1
12.6
78
303
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
135.0
12.5
13
*
G93.3
ICD-10 Finland
Postviral fatigue syndrome
135.0
12.5
13
*
R1250
NOMESCO Finland
Evaluation of functional capability
11.2
12.5
23
22
SPAT1215
SPAT
Assessment of need for medical rehabilitation
5.2
12.3
38
80
K59.09
ICD-10 Finland
Constipation, unspecified
4.5
12.0
43
106
M48.0
ICD-10 Finland
Spinal stenosis
3.2
11.1
65
239
N06AX21
ATC
duloxetine; oral
3.3
11.0
60
210
N04BC06
ATC
cabergoline; oral (dopamine agonists)
44.9
11.0
13
*
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
12.5
11.0
19
16
M79.6
ICD-10 Finland
Pain in limb
2.3
10.8
140
810
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
+∞
10.5
10
*
N04BC07
ATC
apomorphine; parenteral
+∞
10.5
10
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.2
10.4
40
106
M03BX01
ATC
baclofen; systemic
12.7
10.0
17
14
R4130
NOMESCO Finland
Speech therapy
8.8
9.7
20
24
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.6
9.6
76
338
N28
ICPC
Limited function/disability (N)
9.1
9.4
19
22
F02.39
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
+∞
9.4
9
*
M01AH05
ATC
etoricoxib; oral
2.1
9.4
205
1463
H02AA02
ATC
fludrocortisone; oral
16.2
9.1
14
9
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
7.8
9.1
20
27
D21
ICPC
Swallowing problem
11.2
8.9
16
15
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.5
8.5
39
121
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.8
8.4
27
60
R35
ICD-10 Finland
Polyuria
3.7
8.3
36
106
L03
ICPC
Low back symptom/complaint
2.2
8.3
94
500
L86
ICPC
Back syndrome with radiating pain
4.1
8.2
31
81
M54.5
ICD-10 Finland
Low back pain
2.1
8.2
116
679
I95.1
ICD-10 Finland
Orthostatic hypotension
5.0
8.1
25
53
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.0
7.9
46
170
R13
ICD-10 Finland
Dysphagia
3.3
7.8
39
129
M35.7
ICD-10 Finland
Hypermobility syndrome
15.5
7.8
12
8
N06AX16
ATC
venlafaxine; oral
2.6
7.7
58
250
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
25.7
7.6
10
*
M03BC01
ATC
orphenadrine (citrate); systemic
2.2
7.5
89
481
N05BA04
ATC
oxazepam; oral
2.1
7.5
97
543
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
7.5
110
651
WX002
NOMESCO Finland
Sedation and analgesia
2.2
7.5
81
420
L17
ICPC
Foot/toe symptom/complaint
2.1
7.5
100
567
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.0
7.3
41
147
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
7.6
7.3
16
22
SPAT1216
SPAT
Assessment of functional ability
2.4
7.2
67
323
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.7
7.1
30
87
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
14.2
6.9
11
8
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
3.7
6.9
29
84
N02BE01
ATC
paracetamol; systemic, rectal
2.4
6.7
286
2472
N29
ICPC
Neurological sympt/complt other
5.7
6.7
18
33
H50.52
ICD-10 Finland
Exophoria
23.1
6.7
9
*
AA5EN
NOMESCO Finland
Brain reseptor or transprot protein distribution isotope imaging
23.1
6.7
9
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.4
6.7
59
276
U04
ICPC
Incontinence urine
4.0
6.6
25
66
N06AB10
ATC
escitalopram; oral
2.2
6.6
71
363
SPAT1301
SPAT
No procedures
1.9
6.5
118
749
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
8.4
6.4
13
16
N02AX02
ATC
tramadol; systemic, rectal
1.8
6.4
147
1012
AAW01
NOMESCO Finland
Implantation of intracranial stimulation device
+∞
6.3
6
*
N04BC02
ATC
pergolide; oral
+∞
6.3
6
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.8
6.3
25
70
WX290
NOMESCO Finland
Other blockade of nerve
1.8
6.2
132
881
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
6.2
65
329
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.5
6.2
51
228
A02BC03
ATC
lansoprazole; oral
1.9
6.1
112
710
XF606
NOMESCO Finland
Ortostatic test
12.8
6.1
10
8
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
6.1
64
325
WX402
NOMESCO Finland
General anaesthesia
2.2
6.1
62
311
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
6.2
6.1
15
25
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
6.0
64
327

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
186
999
2.71
19.87
4.2
3.0
—
—
—
0
0
301
2112
3.13
18.26
6.8
4.5
8988.33
2143.74
e6/l
—
6
38
278
1895
2.79
17.33
5.3
4.7
6.29
6.72
mmol/l
4.99
267
1776
250
1619
2.62
17.29
6.8
6.5
1.21
1.22
mmol/l
0.71
208
1372
234
1490
2.51
16.43
6.6
5.6
1.20
1.22
mmol/l
1.91
215
1348
177
997
2.46
16.24
2.6
2.1
227.74
172.25
u/l
0.35
171
931
133
693
2.42
14.10
1.8
1.7
390.01
453.11
pmol/l
2.06
113
563
125
638
2.44
13.83
1.8
1.7
1409.02
1260.56
nmol/l
0.80
94
479
87
378
2.69
13.44
3.9
7.6
1.55
1.27
mmol/l
0.30
74
304
127
681
2.31
12.34
2.9
2.5
5.77
4.73
e6/l
0.50
115
600
152
879
2.22
12.30
3.7
2.9
—
—
—
0
0
228
1553
2.19
12.11
5.2
3.8
0.00
0.00
estimate
0.00
47
301
152
891
2.18
11.78
4.7
4.2
—
—
—
0
0
228
1566
2.16
11.68
6.7
5.0
0.00
0.00
estimate
0.00
49
301
230
1587
2.16
11.62
5.3
3.8
0.00
0.01
estimate
0.50
48
292
163
986
2.15
11.62
3.8
3.2
24.50
124.42
e6/l
0.89
129
763
209
1396
2.12
11.43
5.2
4.6
35.32
35.40
g/l
0.07
193
1304
204
1353
2.11
11.33
9.4
8.8
1.19
1.22
inr
0.28
59
392
153
910
2.15
11.33
3.7
3.0
0.24
0.42
e6/l
1.17
120
679
286
2189
2.28
10.61
6.0
4.4
—
—
—
0
0
162
1004
2.08
10.60
5.8
3.7
7.41
7.40
ph
0.67
36
185
178
1147
2.05
10.42
4.4
3.7
131.31
101.36
e6/l
0.15
136
820
194
1305
2.01
9.92
4.6
2.6
135.48
127.62
ug/l
0.23
172
1193
135
801
2.07
9.77
1.7
1.6
19.24
20.74
nmol/l
0.61
118
671
56
231
2.67
9.41
2.9
4.9
—
—
—
0
0
359
3135
4.21
8.98
22.3
14.8
24.75
23.55
mg/l
0.32
309
2504
119
692
2.05
8.97
5.7
4.2
1.02
1.02
kg/l
0.57
19
92
140
867
1.98
8.82
5.5
4.0
0.00
0.01
estimate
0.50
44
299
193
1334
1.92
8.75
2.4
2.0
90.30
95.22
pmol/l
0.95
112
658
95
524
2.09
8.17
2.8
1.8
28.81
29.47
s
0.76
89
504
206
1477
1.87
8.13
4.2
4.0
—
—
—
0
0
306
2508
2.18
8.08
6.7
7.7
78.04
79.48
u/l
0.26
289
2342
111
655
1.99
7.90
3.3
2.8
570.24
560.97
mosm/kgh2o
0.17
100
557
183
1296
1.80
7.23
4.2
3.8
33.17
58.54
ng/l
0.46
143
950
294
2427
1.97
6.84
4.1
3.9
15.14
14.90
pmol/l
0.72
261
2172
364
3292
4.31
6.84
26.0
17.1
139.81
139.69
mmol/l
0.47
356
3207
364
3303
4.20
6.56
26.3
17.2
3.95
3.98
mmol/l
1.25
356
3215
20
58
3.59
6.09
5.0
3.1
—
—
—
0
0
118
772
1.77
5.83
2.8
2.1
3.14
3.31
mg/l
0.22
93
664
66
360
2.01
5.72
2.1
1.6
—
—
—
0
0
80
469
1.90
5.62
4.7
2.2
2.20
2.35
g/l
1.45
71
435
32
130
2.60
5.53
3.6
4.5
—
—
—
0
0
143
1006
1.68
5.36
2.8
2.4
—
—
—
0
0
154
1108
1.66
5.28
2.7
3.4
2.33
2.36
mmol/l
1.59
138
969
19
59
3.34
5.24
3.9
2.6
16.41
15.98
%
—
10
25
111
734
1.73
5.21
5.5
3.7
—
—
—
0
0
85
520
1.82
5.20
4.5
2.2
13.77
12.80
umol/l
0.50
75
480
357
3267
2.84
5.05
21.3
14.0
—
—
—
0
0
56
303
2.00
4.95
2.2
1.8
398.51
379.56
nmol/l
0.30
51
282
96
619
1.74
4.89
4.6
3.7
77.54
209.95
ng/l
1.57
74
511
367
3463
3.50
4.74
31.9
21.8
6.62
6.70
e9/l
0.24
359
3365
367
3463
3.50
4.74
31.9
21.8
4.33
4.47
e12/l
5.79
359
3365
367
3464
3.48
4.74
32.1
21.9
130.48
135.13
g/l
7.41
361
3410
367
3462
3.51
4.74
31.8
21.7
30.37
30.39
pg
0.11
361
3410
367
3462
3.51
4.74
31.8
21.8
246.49
246.94
e9/l
0.05
359
3374
367
3462
3.51
4.74
31.8
21.7
91.51
91.39
fl
0.24
361
3410
280
2384
1.68
4.60
4.2
4.2
12.72
12.34
mm/h
0.13
253
2195
328
2923
1.96
4.60
5.1
4.7
1.93
2.34
mu/l
0.49
299
2650
122
852
1.64
4.58
4.5
3.4
—
—
—
0
0
271
2296
1.65
4.46
4.2
4.1
—
—
—
0
0
74
455
1.78
4.41
5.0
2.2
23.82
21.77
%
0.60
60
390
141
1028
1.59
4.41
2.6
3.1
1179.40
1118.44
ng/l
0.08
116
873
82
521
1.73
4.36
3.4
3.0
3.19
2.39
e6/l
0.24
41
282
47
252
1.99
4.26
2.2
3.3
147.40
185.27
ng/l
0.40
40
230
50
278
1.92
4.09
2.9
3.9
1.21
1.23
mmol/l
1.21
42
240
49
273
1.91
3.98
5.1
3.8
—
—
—
0
0
169
1316
1.52
3.80
2.6
2.2
76.27
77.79
nmol/l
0.32
151
1158
49
278
1.88
3.77
4.2
3.3
—
—
—
0
0
17
61
2.87
3.74
1.6
1.3
—
—
—
0
0
14
46
3.12
3.56
1.6
1.3
111.93
105.00
u/ml
—
7
10
8
13
6.26
3.52
1.1
1.0
110.38
132.15
nmol/l
—
8
13
211
1745
1.48
3.40
4.3
6.3
10.45
11.31
umol/l
1.13
197
1648
10
27
3.78
3.37
1.5
1.1
—
—
—
0
0
60
375
1.71
3.36
1.9
2.7
1.55
1.83
%
1.81
52
341
137
1044
1.49
3.31
2.3
2.4
56.85
56.57
u/l
0.02
124
962
18
72
2.58
3.26
1.6
1.3
3.50
8.96
e6/l
0.60
12
55
193
1577
1.46
3.26
5.5
5.7
0.53
0.59
e9/l
4.24
170
1358
193
1585
1.45
3.13
5.5
5.7
0.04
0.04
e9/l
0.69
169
1370
195
1606
1.44
3.10
5.5
5.7
1.67
1.92
e9/l
2.09
173
1420
89
631
1.54
3.00
2.8
3.0
2.43
2.46
mmol/l
2.61
78
559
5
5
10.11
2.98
7.2
3.0
—
—
—
0
0
43
254
1.78
2.93
9.0
7.7
—
—
—
0
0
48
296
1.71
2.83
5.8
3.3
3.16
2.10
mmol/l
1.44
37
237
21
97
2.23
2.82
4.7
3.2
—
—
—
0
0
195
1627
1.41
2.78
5.5
6.0
0.17
0.19
e9/l
2.17
174
1434
14
54
2.65
2.73
1.6
1.4
—
—
—
0
0
135
1058
1.43
2.73
5.2
5.8
—
—
—
0
0
14
55
2.61
2.64
3.2
2.5
—
—
—
0
0
26
136
1.98
2.57
1.7
2.0
1.41
4.34
ug/l
0.70
21
121
12
44
2.78
2.57
1.2
1.5
—
—
—
0
0
7
16
4.44
2.48
3.0
2.3
—
—
—
0
0
172
1428
1.38
2.42
5.4
5.8
0.68
0.69
%
0.03
159
1331
94
703
1.45
2.41
2.2
1.6
0.89
1.29
mg/l
1.82
80
548
106
812
1.43
2.39
1.5
1.4
—
—
—
0
0
286
2590
1.44
2.33
27.9
17.9
13.60
13.73
%
0.86
279
2545
30
171
1.82
2.32
5.5
9.5
—
—
—
0
0
68
481
1.51
2.30
2.8
1.9
—
—
—
0
0
6
13
4.67
2.28
7.5
3.6
21.17
10.20
mu/l
—
6
13
7
18
3.94
2.26
1.6
1.2
—
—
—
0
0
18
87
2.12
2.21
1.7
1.3
32.64
29.31
iu/l
0.16
18
73
46
302
1.60
2.16
3.2
2.4
43.38
32.86
u/l
0.34
39
249
175
1476
1.35
2.15
5.4
5.8
2.65
2.80
%
0.48
161
1373
353
3359
1.83
2.14
10.8
11.0
18.41
25.63
u/l
21.12
333
3233
33
199
1.72
2.14
1.2
1.3
—
51.05
—
0
13
43
280
1.60
2.09
2.1
2.9
57.80
72.36
e9/l
2.05
32
220
284
2587
1.40
2.08
29.8
19.2
331.52
332.12
g/l
0.58
279
2578
175
1483
1.34
2.06
5.4
6.1
8.05
8.65
%
2.32
162
1389
175
1487
1.33
2.01
5.3
5.7
60.24
57.60
%
2.59
162
1393
212
1855
1.33
1.97
6.7
9.2
4.26
4.12
e9/l
0.37
189
1633
176
1512
1.31
1.82
5.4
6.0
25.03
27.48
%
2.41
162
1407
165
1406
1.31
1.80
11.8
9.7
0.00
0.00
e9/l
0.41
139
1154
64
472
1.43
1.76
1.2
1.2
—
—
—
0
0
9
36
2.54
1.75
2.4
1.8
—
—
—
0
0
54
391
1.44
1.64
2.1
1.7
—
—
—
0
0
15
77
1.99
1.61
1.3
1.2
—
—
—
0
0
14
70
2.04
1.61
3.2
2.5
8.76
7.94
kpa
1.21
14
63
8
32
2.53
1.60
1.8
1.4
—
—
—
0
0
8
32
2.53
1.60
1.0
1.3
—
—
—
0
0
19
107
1.82
1.58
18.6
10.6
—
—
—
0
0
36
244
1.53
1.51
1.9
2.1
—
—
—
0
0
18
101
1.82
1.51
1.4
1.4
255.13
279.89
ug/g
0.20
12
63
7
28
2.53
1.46
1.4
1.2
—
—
—
0
0
9
40
2.28
1.41
1.3
1.3
22.92
61.55
mu/l
—
9
35
98
804
1.30
1.37
5.2
6.7
—
—
—
0
0
41
294
1.44
1.33
2.6
2.5
6.88
6.19
ug/l
0.11
34
264
299
2811
1.31
1.32
25.5
15.6
37.91
39.57
%
1.51
165
1923
6
24
2.52
1.31
1.8
1.3
—
—
—
0
0
10
48
2.11
1.29
1.2
1.7
—
—
—
0
0
46
341
1.40
1.26
2.0
2.3
162.92
142.32
ug/g
0.27
36
276
84
684
1.29
1.24
3.7
4.7
—
—
—
0
0
91
1090
0.78
1.24
3.1
3.1
—
—
—
0
0
38
273
1.44
1.23
2.1
4.4
1.78
0.78
%
—
9
96
11
56
1.99
1.23
1.1
1.3
—
—
—
0
0
11
56
1.99
1.23
1.1
1.3
—
—
—
0
0
11
56
1.99
1.23
1.1
1.3
—
—
—
0
0
5
19
2.65
1.22
1.2
4.9
—
—
—
0
0
225
2056
1.23
1.21
3.2
3.2
38.79
51.70
u/l
1.42
201
1903
39
283
1.42
1.20
2.3
1.5
—
—
—
0
0
48
364
1.37
1.16
3.2
2.8
6.57
8.53
umol/l
0.34
43
322
18
111
1.65
1.14
2.3
2.0
209.21
264.73
ug/l
0.27
18
102
19
120
1.61
1.11
1.3
1.2
—
3.42
—
0
8
53
412
1.33
1.10
1.5
1.4
—
—
—
0
0
35
255
1.41
1.07
2.2
4.5
0.63
0.11
%
—
8
88
89
1052
0.80
1.07
4.2
3.9
20.17
7.84
mg/mmol
0.75
60
641
7
33
2.14
1.06
1.1
1.4
—
—
—
0
0
50
388
1.33
1.05
1.3
1.3
—
—
—
0
0
80
663
1.26
1.04
1.2
1.2
1.79
1.64
u/ml
0.06
16
182
7
34
2.08
1.03
1.4
1.2
—
—
nmol/l
—
0
0
10
53
1.91
1.02
1.5
2.7
104.80
105.91
mmol/l
—
10
53
10
53
1.91
1.02
1.5
2.7
4.01
3.97
mmol/l
—
10
53
10
53
1.91
1.02
1.5
2.7
—
—
—
0
0
9
159
0.56
1.00
1.3
1.5
—
—
—
0
0
289
3029
0.80
1.00
3.7
4.2
1.15
1.28
mmol/l
3.18
251
2755
41
311
1.36
1.00
2.9
4.2
—
—
—
0
0
7
35
2.02
1.00
1.1
1.2
—
—
—
0
0
13
211
0.60
1.00
1.5
1.4
—
—
—
0
0
18
270
0.65
0.99
1.2
1.5
—
—
—
0
0
5
23
2.19
0.98
1.4
1.2
—
—
—
0
0
5
23
2.19
0.98
2.8
1.7
9.62
10.60
%
—
5
23
17
108
1.60
0.98
1.1
1.1
—
—
—
0
0
7
36
1.96
0.97
1.4
1.2
—
—
—
0
0
7
36
1.96
0.97
7.3
2.6
—
—
—
0
0
9
50
1.82
0.97
1.2
3.0
3.15
4.66
e9/l
—
9
50
67
548
1.27
0.97
1.3
1.3
34.17
42.49
iu/ml
0.27
20
168
53
421
1.30
0.96
1.4
1.3
386.67
505.88
titre
—
6
102
13
208
0.61
0.95
1.2
1.4
—
—
—
0
0
54
431
1.30
0.94
15.2
20.4
1.44
1.34
inr
—
7
53
9
52
1.75
0.93
1.1
1.4
—
—
—
0
0
9
52
1.75
0.93
1.4
1.5
—
—
—
0
0
15
94
1.62
0.92
1.1
1.2
—
—
—
0
0
10
56
1.81
0.88
4.1
1.7
66.80
60.35
%
—
10
56
22
154
1.46
0.85
1.3
1.3
—
—
—
0
0
301
3128
0.81
0.85
4.3
4.6
1.47
1.48
mmol/l
0.07
269
2860
114
1002
1.20
0.85
3.9
3.9
—
—
—
0
0
32
242
1.35
0.82
2.3
4.6
0.00
0.12
%
—
6
75
8
47
1.72
0.81
1.1
1.3
—
—
—
0
0
20
140
1.45
0.78
2.8
1.7
—
—
—
0
0
0
27
0.00
0.77
0.0
2.2
—
771.08
—
0
12
9
53
1.71
0.76
1.2
3.5
54.78
59.40
%
—
9
53
5
25
2.01
0.73
9.2
2.8
—
—
—
0
0
87
992
0.84
0.72
3.3
3.1
2155.70
182.72
mg/l
1.00
64
630
9
57
1.59
0.71
1.1
1.3
—
—
—
0
0
25
188
1.35
0.68
1.4
1.2
66.46
119.63
iu/ml
—
5
74
323
3130
1.23
0.68
4.5
4.8
5.90
6.00
mmol/l
0.72
285
2857
11
70
1.59
0.66
4.4
2.5
—
—
—
0
0
40
325
1.26
0.64
2.3
1.5
—
—
—
0
0
5
30
1.68
0.61
1.2
1.2
—
—
—
0
0
31
246
1.28
0.60
2.2
4.3
0.50
0.37
%
—
6
70
306
3150
0.85
0.58
4.3
4.7
4.57
4.64
mmol/l
0.46
274
2899
96
862
1.15
0.55
2.0
2.7
328.10
8850.47
umol/l
4.42
82
724
11
159
0.68
0.55
4.1
3.5
—
—
—
0
0
22
170
1.31
0.53
2.0
2.4
—
—
—
0
0
23
179
1.30
0.52
4.7
3.5
—
—
—
0
0
92
1018
0.87
0.52
3.2
3.1
7.59
7.44
mmol/l
0.12
82
842
5
82
0.60
0.46
1.6
1.3
—
—
—
0
0
7
50
1.41
0.45
1.9
3.0
—
—
—
0
0
27
221
1.24
0.43
6.4
2.5
—
—
—
0
0
5
32
1.57
0.42
2.4
2.8
—
—
—
0
0
5
33
1.52
0.41
1.8
1.3
—
—
—
0
0
23
186
1.25
0.41
1.9
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.9
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
315
3216
0.87
0.40
4.8
5.3
2.68
2.72
mmol/l
0.29
282
2941
5
35
1.43
0.39
1.6
1.3
—
—
—
0
0
13
98
1.34
0.38
5.5
4.6
—
—
—
0
0
16
125
1.29
0.37
1.0
1.0
—
—
—
0
0
9
70
1.29
0.37
1.1
1.2
10.22
11.95
u/l
—
9
56
59
655
0.88
0.36
3.4
3.0
0.67
0.73
ug/l
0.45
41
446
6
43
1.40
0.35
2.3
1.2
—
—
—
0
0
12
155
0.77
0.34
1.2
1.6
—
—
—
0
0
7
52
1.35
0.31
2.1
2.5
—
—
—
0
0
13
102
1.28
0.30
1.8
1.6
—
—
—
0
0
7
57
1.23
0.29
1.0
1.8
—
—
—
0
0
119
1125
1.08
0.28
4.7
4.9
1.92
2.34
ug/l
0.69
110
1001
24
207
1.17
0.25
3.9
3.6
7.44
7.41
ph
—
6
23
85
906
0.92
0.25
1.7
1.7
1.33
1.35
mmol/l
0.08
71
755
9
74
1.22
0.25
1.3
1.2
—
—
—
0
0
9
76
1.19
0.25
1.7
1.6
—
—
—
0
0
58
534
1.10
0.24
1.4
1.3
1.47
14.16
u/ml
3.39
24
205
5
39
1.29
0.23
1.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
86.55
—
0
10
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
7
61
1.15
0.17
1.4
2.4
—
—
—
0
0
10
82
1.23
0.17
2.9
3.9
—
—
—
0
0
11
93
1.19
0.14
1.0
1.1
—
—
—
0
0
25
227
1.11
0.14
1.1
1.2
—
—
—
0
0
19
212
0.89
0.14
2.6
1.8
1.07
1.53
g/l
1.02
19
193
124
1279
0.95
0.14
2.0
2.1
—
—
—
0
0
9
108
0.83
0.13
1.6
1.2
1.25
1.20
g/l
—
9
103
304
3008
1.06
0.13
6.2
6.1
39.51
40.06
mmol/mol
0.53
274
2787
9
110
0.81
0.13
2.1
1.7
—
—
—
0
0
35
374
0.93
0.12
2.9
4.1
2.33
42.70
ug/l
1.19
28
318
63
608
1.04
0.08
1.7
1.4
3.23
2.66
g/l
0.21
32
356
7
67
1.05
0.08
2.1
1.5
—
—
—
0
0
19
204
0.93
0.07
2.5
3.1
3.74
3.87
e9/l
0.15
11
154
42
403
1.05
0.07
1.4
1.2
—
—
—
0
0
9
102
0.88
0.06
1.4
1.2
0.25
0.24
g/l
—
9
97
10
91
1.10
0.04
1.2
1.3
—
2.67
—
0
16
27
262
1.03
0.02
1.4
1.4
—
—
—
0
0
14
134
1.05
0.00
1.9
2.8
—
—
—
0
0
20
206
0.97
0.00
1.2
1.2
—
—
—
0
0
14
139
1.01
0.00
1.2
1.3
—
—
—
0
0
31
315
0.98
0.00
1.6
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
5
59
0.85
0.00
2.2
3.2
12.80
29.17
u/ml
—
5
59
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
3.1
—
6.04
—
0
7
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
3.4
—
8111.43
—
0
7
9
92
0.98
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
6.0
—
—
—
0
0
30
300
1.00
0.00
1.5
1.4
—
—
—
0
0
7
75
0.93
0.00
4.6
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
1.80
—
0
6

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: PDMED_ROTIGOTINE – Use of rotigotine

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).