Other disorders affecting eyelid function

H7_EYELIDFUNC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H02.5
  • Hospital discharge: ICD-9 3744
  • Cause of death: ICD-10 H02.5
  • Cause of death: ICD-9 3744

2 out of 7 registries used, show all original rules.

333

4. Check minimum number of events

None

333

5. Include endpoints

None

333

6. Filter based on genotype QC (FinnGen only)

322

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H02
Name in latin
Aliae morbositates functionem palpebrarum afficientes

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1353 726 623
Only index persons 1292 696 596
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.03 0.02
Median age at first event (years)
Whole population 63.72 62.36 65.24
Only index persons 63.77 62.36 65.41

-FinnGen-

Key figures

All Female Male
Number of individuals 322 175 147
Unadjusted period prevalence (%) 0.06 0.06 0.07
Median age at first event (years) 64.54 61.45 68.22

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
333
Matched controls
3330
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
+∞
307.7
326
*
H02.3
ICD-10 Finland
Blepharochalasis
506.7
190.5
173
7
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
1608.5
119.5
109
*
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
+∞
100.2
91
*
H02.4
ICD-10 Finland
Ptosis of eyelid
142.5
74.6
77
7
WX720
NOMESCO Finland
Own respiration
14.2
74.4
75
67
WX704
NOMESCO Finland
Intubation
9.8
66.7
90
121
WX725
NOMESCO Finland
Noninvasive ventilation
8.7
48.1
68
95
H04.10
ICD-10 Finland
Dry eye syndrome
8.1
42.8
64
95
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
5.1
41.8
118
323
WX100
NOMESCO Finland
Conjunctival surface anesthesia
5.6
41.4
97
226
TPH04
NOMESCO Finland
Cathetrisation of vein
4.6
39.8
141
460
QAJ10
NOMESCO Finland
Browlift
+∞
38.3
36
*
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
+∞
29.6
28
*
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
318.3
29.3
29
*
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
+∞
27.5
26
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
27.5
26
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
9.3
26.2
33
39
WX110
NOMESCO Finland
Infiltration anesthesia
4.6
25.6
281
1798
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
7.6
24.7
37
54
F29
ICPC
Eye symptom/complaint other
4.4
21.2
61
163
F16
ICPC
Eyelid symptom/complaint
7.4
21.2
32
47
WX400
NOMESCO Finland
Inhalation anesthesy
6.5
19.4
33
55
TPH07
NOMESCO Finland
Cathetrisation of artery
3.9
19.2
66
200
ZXA10
NOMESCO Finland
Bilateral
3.2
18.9
93
356
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.7
17.6
171
936
SPAT1301
SPAT
No procedures
2.7
17.3
142
714
SPAT1153
SPAT
Removal of sutures
2.7
17.0
145
741
H02.1
ICD-10 Finland
Ectropion of eyelid
+∞
15.7
15
*
CD2S4
NOMESCO Finland
Photography of eye
47.4
15.2
18
*
H03BB01
ATC
carbimazole; oral
5.9
15.0
28
51
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.0
14.8
45
124
WX702
NOMESCO Finland
Supraglottic ventilation device
4.5
14.8
38
92
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
4.7
14.7
36
84
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.6
14.6
54
171
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.9
14.4
85
355
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
6.8
14.3
23
36
H02.8
ICD-10 Finland
Other specified disorders of eyelid
+∞
13.6
13
*
CBN30
NOMESCO Finland
Shortening of canthal ligament
+∞
13.6
13
*
H02.7
ICD-10 Finland
Other degenerative disorders of eyelid and periocular area
145.7
13.5
14
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
13.0
100
476
N03AX12
ATC
[U] gabapentin; oral
2.7
12.6
83
366
S18
ICPC
Laceration/cut
2.3
12.2
180
1134
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
+∞
11.5
11
*
H02.2
ICD-10 Finland
Lagophthalmos
+∞
11.5
11
*
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
+∞
11.5
11
*
CBJ41
NOMESCO Finland
Shortening of superior tarsal muscle (Müller's muscle)
+∞
11.5
11
*
CAC20
NOMESCO Finland
Lateral decompression of orbit
+∞
11.5
11
*
H01.0
ICD-10 Finland
Blepharitis
4.7
10.9
26
59
SPAT1263
SPAT
Sampling
2.1
10.5
158
985
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
+∞
10.5
10
*
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
+∞
10.5
10
*
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
+∞
10.5
10
*
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
10.5
10
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.2
10.4
132
769
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.1
10.1
45
159
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
102.8
9.5
10
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.0
9.5
46
171
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
+∞
9.4
9
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.7
9.3
31
91
WX402
NOMESCO Finland
General anaesthesia
2.3
9.1
86
441
H25.1
ICD-10 Finland
Senile nuclear cataract
2.1
9.0
111
633
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
7.3
8.7
20
29
XQ845
NOMESCO Finland
Dermatoscopy
9.4
8.6
17
19
UDC00
NOMESCO Finland
Ear microscopy
3.0
8.6
41
151
KMAK, ,
NOMESCO Finland
2.0
8.4
172
1172
H062, E050,
ICD-10 Finland
+∞
8.4
8
*
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
9.3
8.1
16
18
R44
ICPC
Respiratory, Preventive immunization/medic
10.4
8.1
15
15
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
7.9
56
252
L17
ICPC
Foot/toe symptom/complaint
2.0
7.8
113
678
ZXA05
NOMESCO Finland
Left side
2.1
7.8
96
543
I20.99
ICD-10 Finland
Angina pectoris, unspecified
3.1
7.8
33
113
AA1AD
NOMESCO Finland
CT of head and brain
2.0
7.8
102
592
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.7
7.7
18
40
SAA03
NOMESCO Finland
Extended examination of mouth
1.9
7.7
135
865
S04
ICPC
Lump/swelling localized
2.8
7.7
41
160
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
18.9
7.6
11
6
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.3
7.5
63
306
SPAT1097
SPAT
Recording of ECG
2.3
7.4
63
307
G44.2
ICD-10 Finland
Tension-type headache
2.4
7.4
57
266
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
7.4
109
658
QAJ15
NOMESCO Finland
Browlift using video-endoscope
+∞
7.3
7
*
3744A
ICD-9 Finland
Other disorders of eyelids, Other disorders affecting eyelid function
+∞
7.3
7
*
R07.0
ICD-10 Finland
Pain in throat
3.4
7.3
27
85
OAB50, ,
SPAT
3.4
7.3
26
80
A02BC03
ATC
lansoprazole; oral
2.0
7.3
110
669
WX002
NOMESCO Finland
Sedation and analgesia
2.1
7.2
75
398
K80
ICPC
Cardiac arrhythmia NOS
2.8
7.2
36
136
G51.0
ICD-10 Finland
Bell palsy
6.6
7.0
17
27
R51.80
ICD-10 Finland
Headache
2.3
7.0
61
300
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
7.0
95
556
ZX114, ,
SPAT
9.6
6.8
13
14
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.2
6.8
27
89
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
6.1
6.7
17
29
C01DA14
ATC
isosorbide mononitrate; oral
2.2
6.5
59
295
CEW99
NOMESCO Finland
Other operation on extraocular muscle
71.2
6.4
7
*
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
18.4
6.3
9
5
D07AB02
ATC
hydrocortisone butyrate; topical
1.9
6.3
103
639
CB9S4
NOMESCO Finland
Photography of eyelids and eyebrows
+∞
6.3
6
*
H05.2
ICD-10 Finland
Exophthalmic conditions
+∞
6.3
6
*
104
Kela drug reimbursment
Thyroid insufficiency
2.8
6.3
33
128
L12
ICPC
Hand/finger symptom/complaint
2.2
6.3
61
314
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
27.2
6.3
8
*
-1, ,
ICPC
3.4
6.3
22
67
SCC01
NOMESCO Finland
Fluoride application or other respective small prophylactic procedure
5.5
6.2
17
32
TQW40, ,
SPAT
2.8
6.2
32
123
R09
ICPC
Sinus symptom/complaint
2.7
6.2
33
129
L05
ICPC
Flank/axilla symptom/complaint
3.0
6.2
28
100
N17
ICPC
Vertigo/dizziness
2.3
6.1
47
219
T86
ICPC
Hypothyroidism/myxoedema
3.8
6.0
18
49

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
70
76
11.40
60.58
6.3
8.0
1.22
1.29
mmol/l
0.22
64
67
63
133
5.61
29.44
6.8
9.6
—
—
—
0
0
132
501
3.71
28.60
4.8
3.8
223.53
384.79
ng/l
0.51
103
394
65
164
4.68
24.47
6.8
7.3
24.94
24.68
mmol/l
0.24
60
157
59
171
3.98
18.28
6.7
4.9
—
—
—
0
0
69
248
3.25
15.30
6.3
7.4
124.86
121.65
g/l
0.70
64
243
139
733
2.54
14.88
2.1
1.6
1.34
1.35
mmol/l
0.06
133
611
298
2300
3.81
14.07
23.8
18.0
334.22
332.31
g/l
3.16
298
2287
71
273
3.03
13.96
6.1
7.2
96.38
95.32
%
1.18
65
262
75
304
2.89
13.38
6.1
7.0
1.86
1.16
mmol/l
1.44
58
249
30
66
4.90
13.11
5.7
1.7
7.63
5.11
iu/l
0.43
21
20
112
575
2.43
12.29
3.7
3.9
1.02
1.02
kg/l
0.13
14
69
185
1188
2.25
11.86
5.2
4.5
35.75
35.40
g/l
0.40
178
1117
72
306
2.73
11.64
5.9
6.9
5.10
5.13
kpa
0.11
67
294
264
1984
2.60
11.53
4.4
3.8
—
—
—
0
0
29
852
0.28
10.99
2.8
3.9
—
—
—
0
0
199
1359
2.15
10.42
7.2
6.6
1.21
1.21
mmol/l
0.09
182
1153
267
2067
2.47
10.07
5.3
3.7
14.77
14.82
pmol/l
0.12
255
1846
138
872
1.99
8.37
3.2
3.1
8.29
7.53
mmol/l
1.11
122
730
299
2519
2.83
8.11
6.3
4.5
1.87
1.92
mu/l
0.30
289
2270
164
1111
1.94
8.03
2.0
1.9
90.10
95.42
pmol/l
0.64
73
565
185
1307
1.93
7.96
10.6
13.3
1.33
1.27
inr
0.28
37
393
71
1224
0.47
7.56
6.7
9.2
0.00
0.00
e9/l
0.55
52
1000
177
1248
1.89
7.51
5.5
5.4
1.21
1.21
mmol/l
0.63
167
1130
130
830
1.93
7.47
3.4
3.6
7.38
7.40
ph
—
6
167
305
2623
2.94
7.42
6.6
5.8
39.66
40.07
mmol/mol
0.41
295
2436
136
885
1.91
7.35
3.6
3.8
4.46
7.73
mg/mmol
1.19
86
558
129
828
1.91
7.25
3.2
3.2
1018.95
206.70
mg/l
0.60
85
545
256
2053
2.07
7.25
4.7
4.0
11.77
12.29
mm/h
0.22
251
1887
60
294
2.27
6.97
1.7
1.5
—
—
—
0
0
225
1789
1.79
5.76
5.1
4.2
—
232.12
—
0
34
84
501
1.90
5.71
1.5
1.7
1021.05
1239.29
nmol/l
1.76
73
379
12
16
7.73
5.68
1.2
1.7
—
—
—
0
0
207
1621
1.73
5.45
5.5
4.2
6.77
6.75
mmol/l
0.04
190
1512
231
1867
1.77
5.42
5.5
4.0
—
—
—
0
0
323
2953
4.12
5.41
11.2
10.3
25.89
25.96
u/l
0.03
317
2840
258
2158
1.87
5.36
6.7
7.4
72.80
78.87
u/l
2.02
251
2008
173
1297
1.69
5.28
2.6
2.5
—
—
—
0
0
308
2751
2.59
5.28
14.4
13.8
23.99
23.18
mg/l
0.17
248
2156
305
2716
2.46
5.20
5.1
4.6
5.88
6.00
mmol/l
1.07
294
2477
34
149
2.43
5.06
6.3
3.4
4.22
4.53
pmol/l
1.31
34
132
316
2872
2.96
4.95
17.9
13.3
—
—
—
0
0
180
1379
1.66
4.95
4.4
5.6
0.21
0.19
e9/l
0.58
170
1221
306
2743
2.43
4.88
4.9
4.5
4.56
4.64
mmol/l
0.68
300
2536
310
2801
2.55
4.74
5.9
5.1
2.61
2.73
mmol/l
1.53
301
2572
6
244
0.23
4.72
1.8
3.5
—
—
—
0
0
27
110
2.58
4.68
1.1
1.0
—
—
—
0
0
325
3053
3.69
4.65
24.0
20.5
30.30
30.37
pg
0.30
325
3001
325
3053
3.69
4.65
24.0
20.6
90.53
91.29
fl
2.56
325
3001
325
3052
3.70
4.65
24.1
20.6
39.57
40.16
%
0.55
229
2861
155
1160
1.63
4.55
3.3
2.7
101.59
129.16
ug/l
1.27
150
1069
173
1332
1.62
4.51
4.4
5.2
0.62
0.59
e9/l
1.11
162
1156
325
3056
3.64
4.49
24.4
20.7
135.10
135.30
g/l
0.09
325
3003
173
1336
1.61
4.43
4.4
5.2
0.04
0.04
e9/l
0.02
162
1162
176
1365
1.61
4.43
4.6
5.3
1.90
1.99
e9/l
0.40
167
1222
114
816
1.60
3.88
3.9
2.9
—
—
—
0
0
301
2730
2.07
3.83
4.6
4.5
1.41
1.48
mmol/l
2.11
294
2505
96
665
1.62
3.72
2.2
2.1
1.82
3.20
mg/l
10.51
90
577
10
20
5.12
3.71
4.1
2.4
13.32
13.10
%
—
10
20
160
1258
1.52
3.51
4.3
5.8
—
—
—
0
0
8
234
0.33
3.34
1.5
3.6
1.25
1.23
mmol/l
—
8
207
34
597
0.52
3.30
1.8
2.8
0.65
0.78
ug/l
0.49
15
386
28
137
2.14
3.27
2.1
2.5
—
—
—
0
0
51
793
0.58
3.24
2.6
2.9
0.59
0.44
e6/l
0.32
34
586
112
839
1.50
2.99
2.3
2.0
254.19
287.40
u/l
0.10
107
790
134
1049
1.46
2.85
3.2
3.3
6.12
5.79
ph
1.15
12
83
73
996
0.66
2.56
3.0
3.6
33.07
90.67
e6/l
1.70
53
712
82
1091
0.67
2.53
2.3
2.1
—
—
—
0
0
7
16
4.44
2.48
5.6
7.4
—
7.45
—
0
5
36
213
1.77
2.48
3.6
3.7
77.64
79.42
ng/l
0.04
36
185
185
1564
1.41
2.48
6.1
9.3
4.00
4.12
e9/l
0.29
177
1374
176
1476
1.41
2.46
4.7
6.2
11.79
11.12
umol/l
0.39
170
1402
137
1102
1.41
2.43
2.7
2.3
80.64
76.69
nmol/l
0.88
131
981
89
662
1.47
2.40
1.4
1.6
20.08
21.39
nmol/l
0.45
82
553
81
592
1.49
2.38
1.6
1.8
426.89
433.88
pmol/l
0.11
73
491
8
22
3.70
2.38
1.6
1.1
1.35
1.71
promille
—
8
16
75
998
0.68
2.27
2.4
3.0
—
—
—
0
0
8
25
3.25
2.11
1.1
1.4
—
—
—
0
0
159
1337
1.36
2.07
3.4
3.6
0.00
0.00
estimate
—
9
289
161
1357
1.36
2.06
3.4
3.6
0.00
0.01
estimate
—
7
250
65
874
0.68
2.05
2.5
3.0
37.80
70.69
e6/l
0.67
48
664
98
763
1.40
2.04
2.4
3.2
—
—
—
0
0
159
1342
1.35
2.00
4.9
4.8
0.00
0.00
estimate
—
8
261
52
359
1.53
2.00
4.7
5.1
1.06
1.04
mmol/l
0.30
52
330
33
206
1.67
1.91
1.3
1.4
—
—
—
0
0
54
381
1.50
1.88
2.3
2.4
20.40
21.65
%
0.26
20
331
0
54
0.00
1.87
0.0
3.3
—
1.98
—
0
35
284
2648
1.49
1.83
3.7
4.1
1.32
1.28
mmol/l
0.35
271
2424
32
202
1.65
1.79
1.6
1.4
—
—
—
0
0
68
884
0.71
1.74
1.9
2.3
—
—
—
0
0
0
46
0.00
1.72
0.0
3.0
—
60.67
—
0
46
14
264
0.51
1.71
2.2
4.6
—
—
—
0
0
13
62
2.14
1.68
1.5
1.8
—
—
—
0
0
205
1826
1.32
1.67
3.2
3.0
47.43
50.36
u/l
0.23
198
1705
5
132
0.37
1.66
13.8
3.8
—
—
—
0
0
10
42
2.42
1.63
1.1
1.1
—
—
—
0
0
5
14
3.61
1.62
1.0
1.3
11.08
17.51
umol/l
—
5
14
5
14
3.61
1.62
2.4
6.4
—
—
—
0
0
26
160
1.68
1.61
1.2
1.2
248.00
145.45
iu/ml
—
10
69
32
208
1.60
1.61
1.2
1.2
—
—
—
0
0
31
458
0.64
1.54
2.2
2.7
10.71
2.27
e6/l
—
10
243
0
43
0.00
1.53
0.0
2.7
—
—
—
0
0
0
45
0.00
1.51
0.0
2.6
—
4.84
—
0
45
0
45
0.00
1.51
0.0
1.8
—
—
—
0
0
77
609
1.34
1.43
1.6
1.7
0.77
1.11
mg/l
1.39
60
465
7
29
2.44
1.40
1.1
1.1
—
—
—
0
0
7
29
2.44
1.40
1.1
1.1
—
—
—
0
0
59
450
1.38
1.37
1.2
1.3
28.52
16.12
u/ml
0.26
14
178
15
257
0.56
1.37
1.5
2.0
0.21
0.21
g/l
0.01
15
242
44
319
1.44
1.36
2.0
1.6
—
—
—
0
0
14
244
0.56
1.35
1.6
1.4
—
—
—
0
0
7
148
0.46
1.35
2.0
3.3
—
—
—
0
0
0
37
0.00
1.35
0.0
1.6
—
32.51
—
0
37
61
470
1.36
1.34
1.3
1.3
51.10
37.23
iu/ml
0.16
24
149
10
191
0.51
1.30
8.4
3.8
5.16
5.11
kpa
—
10
186
74
590
1.33
1.30
1.2
1.2
0.52
1.68
u/ml
1.91
12
157
13
228
0.55
1.29
5.7
3.4
—
—
—
0
0
60
760
0.74
1.28
2.6
2.8
—
—
—
0
0
10
188
0.52
1.25
8.4
3.8
—
7.40
—
0
23
38
515
0.70
1.23
2.2
3.0
2.42
2.45
mmol/l
1.22
32
454
10
50
2.03
1.17
1.0
1.1
—
—
—
0
0
0
33
0.00
1.17
0.0
1.5
—
0.29
—
0
25
0
34
0.00
1.16
0.0
2.2
—
90.39
—
0
34
15
244
0.60
1.15
2.9
2.5
2.32
6.92
ug/l
3.46
15
224
32
234
1.41
0.98
1.7
2.6
61.09
71.70
e9/l
1.59
27
185
0
30
0.00
0.97
0.0
1.1
—
—
—
0
0
7
36
1.96
0.97
1.6
1.5
—
—
—
0
0
9
50
1.82
0.97
1.1
1.9
—
—
—
0
0
15
233
0.63
0.97
3.7
4.5
1.00
0.91
%
—
8
93
6
27
2.24
0.94
1.0
1.1
—
—
—
0
0
47
372
1.31
0.89
1.9
1.7
—
—
—
0
0
73
613
1.24
0.87
3.7
3.6
—
—
—
0
0
26
188
1.42
0.86
3.1
2.7
4.15
6.03
e9/l
0.65
26
151
8
47
1.72
0.81
1.0
1.1
—
—
—
0
0
84
726
1.21
0.76
2.4
2.6
362.37
7789.29
umol/l
3.45
73
635
17
116
1.49
0.76
1.4
1.9
1.40
1.46
g/l
0.18
17
103
46
561
0.79
0.75
1.8
2.8
569.17
539.21
mosm/kgh2o
0.47
36
489
15
218
0.67
0.74
4.9
6.8
—
—
—
0
0
87
759
1.20
0.72
3.3
4.0
—
—
—
0
0
43
348
1.27
0.71
1.3
1.3
—
—
—
0
0
14
203
0.68
0.69
2.6
4.7
1.00
0.53
%
—
9
73
9
59
1.54
0.69
1.1
1.6
—
—
—
0
0
5
92
0.54
0.68
9.0
10.4
—
—
—
0
0
7
43
1.64
0.67
1.0
1.8
—
—
—
0
0
7
44
1.60
0.65
1.9
3.3
—
—
—
0
0
48
571
0.81
0.63
2.0
2.5
3.74
5.00
e6/l
0.55
40
520
98
1092
0.85
0.63
3.2
3.8
41.72
46.74
ng/l
0.15
53
780
6
102
0.58
0.63
4.7
4.0
—
—
—
0
0
27
344
0.77
0.63
2.9
5.7
102.56
103.85
mmol/l
0.65
27
344
42
345
1.25
0.62
1.1
1.3
243.64
412.99
titre
1.17
11
77
6
105
0.56
0.62
1.0
1.1
—
—
—
0
0
30
376
0.78
0.62
1.0
1.3
—
—
—
0
0
5
30
1.68
0.61
1.0
1.2
—
—
—
0
0
13
186
0.69
0.61
1.2
1.5
0.89
1.46
g/l
1.49
13
172
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.5
—
36.07
—
0
20
48
403
1.22
0.59
2.2
1.8
—
—
—
0
0
13
89
1.48
0.59
1.2
1.3
—
4.48
—
0
6
5
87
0.57
0.57
1.8
2.8
25.96
24.92
mmol/l
—
5
87
65
739
0.85
0.53
3.9
3.9
0.00
0.01
estimate
—
7
257
28
346
0.79
0.53
1.4
1.2
—
—
—
0
0
10
67
1.51
0.50
2.2
1.4
267.30
268.65
mu/l
—
10
62
26
320
0.80
0.48
1.1
1.3
—
—
—
0
0
19
146
1.32
0.48
1.3
1.2
182.42
198.92
u/ml
0.05
19
133
20
158
1.28
0.43
2.4
1.5
—
—
—
0
0
8
58
1.39
0.42
1.1
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
0.97
—
0
10
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
4.02
—
0
6
8
59
1.36
0.41
6.9
2.5
—
—
—
0
0
9
66
1.37
0.38
1.1
1.6
—
—
—
0
0
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
9
68
1.33
0.38
1.1
1.6
—
—
—
0
0
9
69
1.31
0.37
1.1
1.6
—
—
—
0
0
9
70
1.29
0.37
1.1
1.6
—
—
—
0
0
9
70
1.29
0.37
1.1
1.5
—
—
—
0
0
5
76
0.65
0.36
6.6
2.9
8.08
8.04
kpa
—
5
76
13
166
0.77
0.34
1.2
1.4
—
—
—
0
0
6
47
1.28
0.32
1.0
1.0
—
—
—
0
0
19
225
0.84
0.27
2.3
2.7
65.82
66.76
g/l
0.31
19
205
12
95
1.27
0.26
1.7
1.5
—
—
—
0
0
9
74
1.22
0.25
1.0
1.1
—
—
—
0
0
15
124
1.22
0.24
1.8
1.7
—
—
—
0
0
63
676
0.92
0.22
5.9
6.7
—
—
—
0
0
5
41
1.22
0.22
1.4
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
4.8
—
51.18
—
0
11
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
3.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
69.34
—
0
5
9
111
0.81
0.20
1.6
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
2.8
—
14.81
—
0
14
30
270
1.12
0.19
1.6
1.5
—
—
—
0
0
23
256
0.89
0.16
1.3
2.5
24.76
32.99
u/l
1.73
17
215
13
149
0.87
0.14
1.0
1.3
—
—
—
0
0
50
529
0.94
0.13
1.2
1.4
1.99
2.64
g/l
2.40
27
315
30
324
0.92
0.13
1.5
1.5
—
—
—
0
0
15
168
0.89
0.12
1.1
1.2
—
—
—
0
0
13
115
1.14
0.10
1.5
3.8
15.31
1548.24
u/ml
0.69
13
98
13
146
0.89
0.10
1.6
1.5
—
—
—
0
0
17
187
0.90
0.10
4.7
2.6
—
—
—
0
0
11
97
1.14
0.09
2.8
2.8
—
—
—
0
0
6
55
1.09
0.09
2.3
2.7
0.85
0.76
nmol/l
—
6
43
6
57
1.05
0.08
1.5
1.8
139.67
246.22
pmol/l
—
6
51
17
185
0.91
0.08
2.1
2.3
—
—
—
0
0
5
60
0.83
0.08
1.6
1.3
16.49
8.86
u/l
—
5
49
7
65
1.08
0.08
4.0
4.2
—
—
—
0
0
6
75
0.80
0.07
1.0
1.2
—
—
—
0
0
8
74
1.08
0.07
1.3
1.2
—
—
—
0
0
8
95
0.84
0.06
1.1
1.1
—
—
—
0
0
95
931
1.03
0.06
2.4
3.5
2.32
2.35
mmol/l
1.61
86
815
21
222
0.94
0.05
1.7
2.5
9.79
10.26
g/l
0.24
21
201
32
307
1.05
0.05
1.7
2.1
54.52
145.15
ug/g
3.89
25
248
75
736
1.02
0.04
1.2
1.4
—
—
—
0
0
11
101
1.09
0.04
1.4
1.3
—
—
—
0
0
24
250
0.96
0.03
1.3
1.4
—
—
—
0
0
23
223
1.03
0.01
6.0
6.9
12.13
9.98
mmol/l
0.67
23
207
24
243
0.99
0.00
1.5
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.7
—
—
—
0
0
7
79
0.88
-0.00
2.3
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
9.06
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
22.22
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
4.79
—
0
7
0
8
0.00
-0.00
0.0
3.5
—
31063.12
—
0
8
5
59
0.85
-0.00
1.4
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
37.86
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
17.50
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_EYELIDFUNC and mortality.

Females

Parameter HR [95% CI] p-value
H7_EYELIDFUNC 0.941 [0.68, 1.3] 0.712
Birth year 0.992 [0.98, 1.0] 0.079

During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 514 females with H7_EYELIDFUNC died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_EYELIDFUNC.

N-year risk Females Males
1 0.081% No data
5 0.507% No data
10 1.238% No data
15 2.395% No data
20 4.239% No data

Relationships between endpoints

Index endpoint: H7_EYELIDFUNC – Other disorders affecting eyelid function

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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