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Other disorders affecting eyelid function

DOID EFO Endpoint Browser PheWeb

H7_EYELIDFUNC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H02.5
  • Hospital discharge: ICD-9 — 3744
  • Cause of death: ICD-10 — H02.5
  • Cause of death: ICD-9 — 3744

2 out of 7 registries used, show all original rules.

292

4. Check minimum number of events

None

292

5. Include endpoints

None

292

6. Filter based on genotype QC (FinnGen only)

292

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H02
Name in latin
Aliae morbositates functionem palpebrarum afficientes

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1353 726 623
Only index persons 1292 696 596
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.03 0.02
Median age at first event (years)
Whole population 63.72 62.36 65.24
Only index persons 63.77 62.36 65.41

-FinnGen-

Key figures

All Female Male
Number of individuals 292 159 133
Unadjusted period prevalence (%) 0.06 0.05 0.06
Median age at first event (years) 64.08 60.62 68.22

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
234
Matched controls
2341
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
4503599627370496.0
316.7
227
*
H02.3
ICD-10 Finland
Blepharochalasis
589.2
130.6
118
*
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
1200.7
87.5
80
*
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
+∞
70.4
64
*
H02.4
ICD-10 Finland
Ptosis of eyelid
226.9
53.4
53
*
WX704
NOMESCO Finland
Intubation
11.5
29.7
58
65
QAJ10
NOMESCO Finland
Browlift
+∞
28.7
27
*
WX720
NOMESCO Finland
Own respiration
15.7
26.0
43
33
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
278.4
25.2
25
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
22.2
21
*
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
+∞
21.2
20
*
TPH04
NOMESCO Finland
Cathetrisation of vein
4.4
20.8
93
306
WX100
NOMESCO Finland
Conjunctival surface anesthesia
6.0
19.5
58
121
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.6
19.4
79
235
WX725
NOMESCO Finland
Noninvasive ventilation
9.9
18.6
38
45
ZXA10
NOMESCO Finland
Bilateral
4.4
18.5
78
238
WX110
NOMESCO Finland
Local anesthesy
4.1
18.5
192
1233
H04.10
ICD-10 Finland
Dry eye syndrome
8.6
16.7
37
50
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
15.1
16.5
27
20
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
+∞
15.8
15
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.7
12.5
59
193
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.8
12.2
117
621
F29
ICPC
Eye symptom/complaint other
4.7
11.2
39
95
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
+∞
10.5
10
*
CBN30
NOMESCO Finland
Shortening of canthal ligament
+∞
10.5
10
*
SPAT1153
SPAT
Removal of sutures
2.6
10.2
102
539
WX400
NOMESCO Finland
Inhalation anesthesy
6.2
10.2
27
48
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.6
10.2
100
523
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.5
9.9
35
87
H03BB01
ATC
carbimazole; oral
8.4
9.9
21
27
SPAT1301
SPAT
No procedures
2.5
9.7
98
520
R44
ICPC
Respiratory, Preventive immunization/medic
22.8
9.5
13
6
CAC20
NOMESCO Finland
Lateral decompression of orbit
+∞
9.4
9
*
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
+∞
9.4
9
*
H02.1
ICD-10 Finland
Ectropion of eyelid
+∞
9.4
9
*
F16
ICPC
Eyelid symptom/complaint
6.1
9.4
25
45
S18
ICPC
Laceration/cut
2.4
9.3
120
715
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
9.6
9.2
18
20
CD2S4
NOMESCO Finland
Photography of eye
52.0
8.7
10
*
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
+∞
8.4
8
*
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
8.4
8
*
H02.7
ICD-10 Finland
Other degenerative disorders of eyelid and periocular area
+∞
8.4
8
*
H25.1
ICD-10 Finland
Senile nuclear cataract
2.5
8.0
74
368
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.8
8.0
34
101
L17
ICPC
Foot/toe symptom/complaint
2.5
7.9
75
376
ZXA05
NOMESCO Finland
Left side
2.4
7.8
76
386
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
82.6
7.5
8
*
N03AX12
ATC
gabapentin; oral
2.7
7.4
52
221
TPH07
NOMESCO Finland
Cathetrisation of artery
3.2
7.4
40
141
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
7.4
79
417
G44.2
ICD-10 Finland
Tension-type headache
3.1
7.3
42
156
H02.2
ICD-10 Finland
Lagophthalmos
+∞
7.3
7
*
H062, E050
ICD-10 Finland
NA
+∞
7.3
7
*
3744A
ICD-9 Finland
Other disorders of eyelids, Other disorders affecting eyelid function
+∞
7.3
7
*
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
7.3
7
*
CBJ41
NOMESCO Finland
Shortening of superior tarsal muscle (Müller's muscle)
+∞
7.3
7
*
WX702
NOMESCO Finland
Supraglottic ventilation device
4.5
7.3
25
61
R07.4
ICD-10 Finland
Chest pain, unspecified
2.3
7.2
75
391
UDC00
NOMESCO Finland
Ear microscopy
3.7
7.0
30
90
SPAT1263
SPAT
Sampling
2.1
6.7
110
699
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
23.3
6.7
9
*
SAA03
NOMESCO Finland
Extended examination of mouth
2.1
6.6
97
586
H02.8
ICD-10 Finland
Other specified disorders of eyelid
71.7
6.5
7
*
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
+∞
6.3
6
*
H05.2
ICD-10 Finland
Exophthalmic conditions
+∞
6.3
6
*
QAJ15
NOMESCO Finland
Browlift using video-endoscope
+∞
6.3
6
*
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
+∞
6.3
6
*
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
63
58
13.58
61.17
5.2
8.2
1.2
1.3
mmol/l
0.10
57
50
58
114
6.10
29.45
5.4
9.4
—
—
—
0
0
119
449
3.79
26.26
4.7
3.7
227.5
340.0
ng/l
0.31
89
358
58
149
4.61
21.39
5.6
7.0
24.8
24.6
mmol/l
0.16
52
139
53
152
4.04
16.73
5.5
4.7
—
—
—
0
0
62
222
3.28
13.91
5.2
7.3
125.6
122.3
g/l
0.67
56
215
64
244
3.08
12.87
5.1
7.1
96.6
95.1
%
2.16
58
235
121
648
2.48
12.47
2.1
1.6
1.3
1.3
mmol/l
0.05
116
539
68
275
2.92
12.28
5.1
6.8
1.7
1.1
mmol/l
1.06
53
219
26
55
5.09
11.90
6.1
1.5
6.2
5.8
iu/l
0.05
19
15
259
2008
3.56
11.78
23.7
18.2
334.1
332.3
g/l
2.55
259
1997
66
277
2.79
11.04
4.7
6.7
5.1
5.1
kpa
0.12
61
267
163
1045
2.27
10.61
5.3
4.4
35.8
35.4
g/l
0.45
156
977
25
742
0.27
9.71
2.8
4.0
—
—
—
0
0
235
1814
2.51
9.14
5.3
3.8
14.8
14.9
pmol/l
0.17
223
1615
228
1739
2.42
9.06
4.4
3.9
—
—
—
0
0
174
1202
2.11
8.72
7.0
6.5
1.2
1.2
mmol/l
0.04
157
1011
264
2181
3.19
8.53
22.2
14.5
39.1
39.9
%
0.57
161
1525
123
756
2.08
8.34
3.3
3.1
8.4
7.5
mmol/l
1.24
107
623
10
11
9.38
8.13
1.2
1.3
—
—
—
0
0
91
511
2.13
7.73
3.6
4.0
1.0
1.0
kg/l
0.35
13
65
146
988
1.96
7.29
9.2
8.9
1.3
1.3
inr
0.25
23
296
121
770
1.98
7.21
3.7
4.0
4.5
7.4
mg/mmol
0.94
78
483
115
722
1.98
7.11
3.2
3.1
1150.2
138.1
mg/l
0.69
75
463
261
2200
2.76
7.01
6.4
4.6
1.9
1.9
mu/l
0.12
251
1975
267
2277
3.02
7.00
6.6
5.8
39.8
40.0
mmol/mol
0.13
257
2107
10
14
7.36
6.74
4.1
2.4
13.3
12.9
%
—
10
14
157
1108
1.90
6.73
5.2
5.3
1.2
1.2
mmol/l
0.54
146
995
64
1091
0.47
6.65
7.0
9.1
0.0
0.0
e9/l
0.55
47
890
283
2573
4.24
6.41
11.3
10.3
25.8
25.8
u/l
0.02
277
2464
114
739
1.89
6.23
3.6
3.6
7.4
7.4
ph
—
6
147
140
975
1.84
6.06
2.1
1.9
93.2
94.1
pmol/l
0.07
62
498
53
268
2.19
5.74
1.7
1.6
—
—
—
0
0
229
1888
1.99
5.52
6.8
7.4
73.7
79.4
u/l
1.58
222
1750
221
1806
1.92
5.39
4.5
4.0
12.1
12.3
mm/h
0.04
216
1649
269
2372
2.70
5.29
5.0
4.7
5.9
6.0
mmol/l
0.90
258
2154
152
1131
1.72
4.90
4.7
4.1
—
—
—
0
0
196
1569
1.76
4.81
5.1
4.2
—
264.5
—
0
28
269
2405
2.50
4.53
14.5
14.0
23.2
23.6
mg/l
0.07
214
1879
181
1434
1.69
4.45
5.3
4.2
6.9
6.7
mmol/l
0.34
165
1329
285
2669
3.83
4.41
24.0
20.9
134.9
135.2
g/l
0.11
285
2620
285
2666
3.88
4.40
23.9
20.8
90.5
91.3
fl
2.69
285
2618
285
2666
3.88
4.40
23.8
20.7
30.3
30.4
pg
0.44
285
2618
271
2437
2.56
4.39
5.9
5.1
2.6
2.7
mmol/l
2.42
262
2226
267
2386
2.39
4.38
4.9
4.6
4.5
4.6
mmol/l
1.03
261
2194
73
453
1.82
4.37
1.5
1.7
1036.5
1241.8
nmol/l
1.42
64
340
5
215
0.22
4.33
2.0
3.6
—
—
—
0
0
276
2511
2.81
4.22
17.7
13.4
—
—
—
0
0
109
768
1.67
4.13
4.2
5.1
—
—
—
0
0
199
1637
1.68
4.05
5.5
4.0
—
—
—
0
0
29
136
2.26
3.76
6.3
3.1
4.2
4.5
pmol/l
1.28
29
119
262
2376
2.00
3.29
4.6
4.6
1.4
1.5
mmol/l
1.59
255
2169
152
1215
1.52
3.14
4.7
5.6
0.2
0.2
e9/l
0.54
144
1073
147
1176
1.50
2.97
4.7
5.2
0.0
0.0
e9/l
0.11
138
1020
149
1199
1.50
2.90
4.9
5.3
1.8
1.9
e9/l
0.54
142
1063
146
1170
1.50
2.90
4.7
5.2
0.6
0.6
e9/l
1.27
134
1010
46
704
0.59
2.78
2.7
3.0
0.7
0.4
e6/l
0.44
30
523
32
180
1.87
2.60
3.9
3.6
81.4
78.7
ng/l
0.05
32
156
8
208
0.37
2.53
1.5
3.7
1.3
1.2
mmol/l
—
8
184
156
1291
1.45
2.50
4.8
6.3
11.7
11.1
umol/l
0.30
150
1218
31
514
0.56
2.50
1.9
3.0
0.7
0.8
ug/l
0.22
14
340
95
716
1.48
2.48
3.6
2.8
—
—
—
0
0
64
881
0.65
2.41
3.1
3.6
36.3
88.9
e6/l
1.25
46
629
61
848
0.65
2.40
2.4
3.0
—
—
—
0
0
9
209
0.41
2.17
7.2
3.5
—
—
—
0
0
47
312
1.60
2.16
5.0
4.9
1.1
1.0
mmol/l
0.34
47
283
6
14
4.35
2.16
6.2
8.0
—
7.4
—
0
5
72
530
1.48
2.08
1.7
1.7
0.8
1.1
mg/l
0.99
57
416
12
50
2.46
2.05
1.6
1.6
—
—
—
0
0
0
50
0.00
1.90
0.0
3.2
—
2.0
—
0
33
74
953
0.70
1.88
2.4
2.0
—
—
—
0
0
49
340
1.53
1.87
2.4
2.3
20.0
21.9
%
0.38
18
292
57
768
0.68
1.86
2.5
3.1
40.3
67.5
e6/l
0.47
42
585
7
23
3.09
1.81
1.1
1.4
—
—
—
0
0
69
520
1.43
1.75
1.6
1.8
432.2
432.1
pmol/l
0.00
63
424
59
781
0.69
1.73
1.9
2.3
—
—
—
0
0
5
13
3.89
1.72
2.4
6.8
—
—
—
0
0
159
1377
1.34
1.69
6.5
9.4
4.1
4.1
e9/l
0.02
153
1208
22
128
1.78
1.65
2.0
2.5
—
—
—
0
0
39
267
1.53
1.59
2.1
1.6
—
—
—
0
0
12
231
0.50
1.58
2.3
4.5
—
—
—
0
0
76
595
1.37
1.54
1.4
1.6
20.1
21.5
nmol/l
0.44
70
496
0
42
0.00
1.54
0.0
2.9
—
60.4
—
0
42
7
27
2.63
1.52
1.1
1.1
—
—
—
0
0
7
27
2.63
1.52
1.1
1.1
—
—
—
0
0
246
2303
1.43
1.43
3.7
4.1
1.3
1.3
mmol/l
0.41
234
2100
11
209
0.51
1.41
3.1
2.4
2.6
7.2
ug/l
2.69
11
191
6
23
2.64
1.37
1.0
1.1
—
—
—
0
0
52
677
0.72
1.36
2.7
2.9
—
—
—
0
0
0
41
0.00
1.32
0.0
2.7
—
—
—
0
0
0
41
0.00
1.32
0.0
2.5
—
4.9
—
0
41
6
131
0.45
1.32
1.8
3.5
—
—
—
0
0
27
178
1.57
1.32
1.2
1.2
—
—
—
0
0
9
45
2.03
1.24
1.0
1.2
—
—
—
0
0
8
37
2.19
1.22
1.1
1.1
—
—
—
0
0
51
653
0.73
1.20
4.0
4.1
0.0
0.0
estimate
—
7
225
6
129
0.45
1.19
5.0
2.4
0.5
0.7
%
—
6
124
0
33
0.00
1.17
0.0
1.6
—
32.6
—
0
33
5
114
0.43
1.15
13.8
4.0
—
—
—
0
0
41
537
0.72
1.11
2.8
4.7
—
—
—
0
0
7
33
2.15
1.06
1.6
1.5
—
—
—
0
0
77
639
1.28
1.03
2.5
2.7
364.7
8485.0
umol/l
3.23
66
548
35
462
0.72
1.00
2.2
3.1
2.4
2.5
mmol/l
0.75
29
405
14
222
0.61
0.99
1.5
2.0
0.2
0.2
g/l
0.12
14
211
0
29
0.00
0.98
0.0
1.6
—
0.3
—
0
23
0
30
0.00
0.98
0.0
1.9
—
90.9
—
0
30
7
36
1.97
0.97
1.9
2.9
—
—
—
0
0
14
220
0.62
0.96
1.6
1.4
—
—
—
0
0
21
142
1.52
0.95
1.2
1.2
183.1
139.8
iu/ml
—
7
56
63
516
1.28
0.94
1.2
1.2
0.5
1.6
u/ml
1.67
11
138
50
397
1.31
0.94
1.2
1.3
30.4
17.4
u/ml
—
10
154
79
666
1.26
0.93
2.4
3.3
—
—
—
0
0
25
177
1.45
0.92
1.5
1.4
—
—
—
0
0
26
187
1.43
0.89
1.3
1.4
—
—
—
0
0
29
214
1.39
0.86
1.7
2.6
61.7
71.3
e9/l
1.21
24
170
39
303
1.33
0.85
1.3
1.4
—
—
—
0
0
133
1195
1.21
0.85
3.4
3.7
0.0
0.0
estimate
—
7
217
131
1181
1.20
0.79
4.8
4.9
0.0
0.0
estimate
—
8
229
10
162
0.60
0.79
8.4
3.8
—
7.4
—
0
20
0
25
0.00
0.79
0.0
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.0
—
—
—
0
0
16
107
1.52
0.78
1.3
1.9
1.4
1.4
g/l
0.10
16
96
51
418
1.27
0.77
1.3
1.3
55.0
37.4
iu/ml
0.16
19
135
130
1178
1.19
0.73
3.3
3.7
0.0
0.0
estimate
—
8
235
5
25
2.02
0.73
1.0
1.2
—
—
—
0
0
10
60
1.69
0.73
2.2
1.5
267.3
271.3
mu/l
—
10
55
5
94
0.52
0.68
5.0
4.1
—
—
—
0
0
12
78
1.56
0.66
1.2
1.3
—
4.5
—
0
6
25
324
0.75
0.66
1.0
1.3
—
—
—
0
0
77
674
1.19
0.63
3.2
3.9
—
—
—
0
0
14
198
0.69
0.62
5.1
6.8
—
—
—
0
0
38
309
1.26
0.62
1.1
1.3
236.0
429.6
titre
—
10
69
41
493
0.80
0.61
1.7
2.7
566.7
552.7
mosm/kgh2o
0.17
31
428
8
51
1.58
0.61
1.1
1.1
—
—
—
0
0
11
72
1.55
0.60
1.8
1.3
22.3
23.6
iu/l
0.06
11
61
42
502
0.81
0.59
1.9
2.5
4.1
5.1
e6/l
0.31
34
450
0
22
0.00
0.59
0.0
2.2
—
539.8
—
0
10
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
86
960
0.85
0.58
3.0
3.8
41.3
49.0
ng/l
0.22
47
690
5
90
0.55
0.56
1.0
1.1
—
—
—
0
0
7
46
1.53
0.48
1.1
2.0
—
—
—
0
0
40
342
1.20
0.44
1.9
1.6
—
—
—
0
0
20
158
1.29
0.43
3.7
2.7
4.1
3.8
e9/l
0.25
20
121
12
161
0.73
0.42
1.2
1.5
0.9
1.4
g/l
1.31
12
149
0
15
0.00
0.41
0.0
1.3
—
1.0
—
0
10
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
32.4
—
0
5
41
356
1.18
0.39
2.2
1.8
—
—
—
0
0
9
68
1.33
0.38
1.0
1.1
—
—
—
0
0
8
115
0.69
0.37
4.9
2.6
26.1
24.1
mmol/l
—
8
104
5
37
1.36
0.37
1.4
1.5
—
—
—
0
0
5
78
0.63
0.36
5.2
3.6
28.8
144.5
mg/l
—
5
60
5
78
0.63
0.36
5.2
3.6
25.2
31.0
mg/l
—
5
61
10
134
0.74
0.35
1.0
1.2
—
—
—
0
0
60
544
1.13
0.33
3.7
3.7
—
—
—
0
0
25
286
0.86
0.25
1.4
1.5
—
—
—
0
0
27
305
0.87
0.23
1.4
1.3
—
—
—
0
0
5
39
1.29
0.23
1.0
1.1
—
—
—
0
0
17
144
1.19
0.22
2.5
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
15.1
—
0
11
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
55
591
0.91
0.21
5.6
7.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
69.3
—
0
5
6
48
1.26
0.20
2.3
2.9
0.9
0.8
nmol/l
—
6
39
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
14
165
0.84
0.20
3.0
2.5
—
22.4
—
0
7
13
154
0.84
0.19
1.2
1.2
—
—
—
0
0
22
194
1.14
0.19
1.5
1.4
—
—
—
0
0
6
53
1.13
0.19
6.3
2.3
—
—
—
0
0
10
121
0.82
0.18
1.6
1.5
—
—
—
0
0
14
163
0.85
0.17
3.6
2.5
—
—
—
0
0
7
61
1.15
0.17
1.3
1.3
—
—
—
0
0
15
129
1.17
0.17
1.1
1.2
217.3
153.7
u/ml
0.16
15
116
12
140
0.85
0.15
1.0
1.4
—
—
—
0
0
24
265
0.90
0.15
1.1
1.3
—
—
—
0
0
10
84
1.20
0.14
1.8
1.6
—
—
—
0
0
10
84
1.20
0.14
2.5
2.9
—
—
—
0
0
21
232
0.90
0.14
4.7
3.3
—
—
—
0
0
18
200
0.89
0.13
2.2
2.6
66.1
66.6
g/l
0.14
18
181
13
148
0.87
0.13
1.5
1.4
—
47.0
—
0
10
44
466
0.93
0.12
1.2
1.4
2.1
2.7
g/l
1.72
23
274
86
830
1.05
0.12
2.5
3.5
2.3
2.3
mmol/l
1.06
77
714
67
642
1.06
0.12
1.2
1.4
—
—
—
0
0
11
126
0.87
0.11
2.4
7.8
25.3
24.6
mmol/l
0.41
11
118
28
261
1.08
0.10
1.7
2.0
57.0
148.4
ug/g
3.17
21
209
12
106
1.14
0.10
1.6
3.7
15.2
1636.4
u/ml
0.66
12
90
5
65
0.77
0.08
1.0
1.2
—
—
—
0
0
7
84
0.83
0.07
1.0
1.1
—
—
—
0
0
9
86
1.05
0.07
1.4
1.3
—
—
—
0
0
18
193
0.93
0.06
1.4
2.4
10.3
10.3
g/l
0.00
18
174
20
209
0.95
0.03
1.3
1.4
—
—
—
0
0
20
193
1.04
0.01
6.2
6.7
12.0
9.8
mmol/l
0.61
20
178
16
162
0.99
0.00
2.2
2.2
—
—
—
0
0
24
235
1.02
0.00
1.5
1.5
—
—
—
0
0
5
58
0.86
0.00
1.2
1.4
—
—
—
0
0
7
75
0.93
0.00
2.6
2.7
—
—
—
0
0
0
7
0.00
0.00
0.0
2.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
5.7
—
0
6
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
0.00
1.2
1.4
—
—
—
0
0
5
49
1.02
0.00
1.2
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
5
59
0.84
0.00
1.2
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
5
59
0.84
0.00
1.2
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
3.0
—
—
—
0
0
5
55
0.91
0.00
1.2
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
3.6
—
59.9
—
0
9
0
6
0.00
0.00
0.0
1.0
—
37.9
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
0.00
5.2
4.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
10
100
1.00
0.00
1.8
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
3.1
—
—
—
0
0
5
52
0.96
0.00
1.6
1.3
16.5
8.6
u/l
—
5
43
9
98
0.92
0.00
1.6
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
9.1
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
17.5
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_EYELIDFUNC and mortality.

Females

Parameter HR [95% CI] p-value
H7_EYELIDFUNC 0.941 [0.68, 1.3] 0.712
Birth year 0.992 [0.98, 1.0] 0.079

During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 514 females with H7_EYELIDFUNC died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_EYELIDFUNC.

N-year risk Females Males
1 0.081% No data
5 0.507% No data
10 1.238% No data
15 2.395% No data
20 4.239% No data

Relationships between endpoints

↥

Index endpoint: H7_EYELIDFUNC – Other disorders affecting eyelid function

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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