No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
626 |
4. Check minimum number of eventsNone |
626 |
5. Include endpointsNone |
626 |
6. Filter based on genotype QC (FinnGen only) |
626 |
Control definitions (FinnGen only)
- Control exclude
- H8_EXTERNAL
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H61
- Name in latin
- Perichondritis auris externae
Similar endpoints
↥List of similar endpoints to Perichondritis of external ear based on the number of shared cases.
Similar with more cases:
- Diseases of external ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 4952 | 2479 | 2432 |
Only index persons | 4192 | 2180 | 2012 |
Unadjusted period prevalence (%) | |||
Whole population | 0.07 | 0.07 | 0.07 |
Only index persons | 0.08 | 0.08 | 0.08 |
Median age at first event (years) | |||
Whole population | 49.13 | 53.02 | 45.11 |
Only index persons | 47.52 | 51.82 | 42.85 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 626 | 336 | 290 |
Unadjusted period prevalence (%) | 0.12 | 0.11 | 0.13 |
Median age at first event (years) | 48.05 | 50.20 | 45.55 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 548
- Matched controls
- 5479
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint H8_PERCHRONDR and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_PERCHRONDR | 1.613 [1.35, 1.93] | < 0.001 |
Birth year | 0.994 [0.99, 1.0] | 0.2 |
During the follow-up period (1.1.1998 — 31.12.2019), 337 out of 1198 females with H8_PERCHRONDR died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_PERCHRONDR | 1.223 [1.0, 1.49] | 0.046 |
Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 259 out of 924 males with H8_PERCHRONDR died.
Mortality risk
Mortality risk for people of age
years, who have H8_PERCHRONDR.N-year risk | Females | Males |
---|---|---|
1 | 0.155% | 0.181% |
5 | 1.027% | 1.238% |
10 | 2.192% | 3.306% |
15 | 4.13% | 6.583% |
20 | 7.925% | 10.866% |
Relationships between endpoints
↥Index endpoint: H8_PERCHRONDR – Perichondritis of external ear
GWS hits: -