No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
82 |
4. Check minimum number of eventsNone |
82 |
5. Include endpointsNone |
82 |
6. Filter based on genotype QC (FinnGen only) |
77 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Multiple congenital exostoses
based on the number of shared cases.
Similar with more cases:
- Multiple congenital exostoses
- Other osteochondrodysplasias
- Other osteochondrodysplasias
- Congenital malformations and deformations of the musculoskeletal system
- Congenital malformations and deformations of the musculoskeletal system
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 77 | 41 | 36 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 25.46 | 21.35 | 30.13 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 82
- Matched controls
- 820
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q78.6
ICD-10 Finland
Multiple congenital exostoses
+∞
115.1
81
*
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
138.7
11.8
12
*
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
56.2
8.9
10
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
25.1
8.3
11
5
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
+∞
7.4
7
*
NFK10
NOMESCO Finland
Fenestration or partial or total excision of bone of femur
+∞
7.4
7
*
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
+∞
7.4
7
*
75665
ICD-8 Finland
Other congenital anomalies of musculoskeletal system, Exostosis cartilaginea multiplex
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
16
68
2.68
2.76
2.4
2.5
0.50
3.62
e6/l
—
8
39
31
186
2.07
2.45
1.7
1.6
107.09
97.90
pmol/l
0.34
15
100
17
80
2.42
2.39
2.1
2.4
0.90
1.05
e6/l
—
9
50
14
60
2.61
2.37
4.5
9.4
103.14
104.25
mmol/l
0.34
14
60
34
216
1.98
2.27
4.1
4.7
35.92
37.44
g/l
0.98
34
207
25
144
2.06
2.17
2.4
2.3
—
—
—
0
0
6
16
3.96
1.97
4.2
24.0
24.50
24.76
mmol/l
—
6
16
5
12
4.36
1.85
1.0
1.3
—
—
—
0
0
40
297
1.68
1.47
2.9
2.6
—
—
—
0
0
5
16
3.26
1.46
1.0
1.3
—
—
—
0
0
14
77
1.99
1.35
3.0
2.7
2.46
2.40
mmol/l
0.68
14
68
59
495
1.68
1.28
4.3
3.7
14.49
14.63
pmol/l
0.18
54
458
31
225
1.61
1.20
3.3
10.1
1.00
1.10
inr
—
9
69
44
354
1.52
1.06
4.2
5.9
6.45
6.36
mmol/l
0.08
39
319
23
161
1.60
1.01
4.5
2.9
0.00
0.02
estimate
—
8
54
68
607
1.70
0.99
14.4
8.6
92.12
93.71
ml/min/173m2
0.20
59
484
20
142
1.54
0.82
2.1
2.0
204.85
216.31
u/l
0.04
20
136
0
24
0.00
0.80
0.0
1.2
—
—
—
0
0
0
24
0.00
0.80
0.0
1.2
—
—
—
0
0
5
26
1.98
0.72
3.0
1.2
—
—
—
0
0
43
364
1.38
0.70
12.6
7.6
3.89
4.15
e9/l
0.48
37
327
7
44
1.64
0.67
2.1
1.4
240.00
284.50
mu/l
—
7
38
13
88
1.57
0.65
3.1
3.6
1774.68
682.93
ng/l
0.33
13
68
5
29
1.77
0.65
1.0
1.4
—
—
—
0
0
0
21
0.00
0.61
0.0
1.0
—
3.58
—
0
15
18
134
1.44
0.59
3.4
3.5
15.63
17.95
mg/mmol
0.08
12
87
6
36
1.72
0.58
2.5
1.5
—
—
—
0
0
11
76
1.52
0.51
2.2
1.6
—
—
—
0
0
7
46
1.57
0.50
3.0
2.7
—
—
—
0
0
13
95
1.44
0.47
1.3
1.2
10.60
30.20
iu/ml
—
5
31
54
491
1.29
0.46
3.4
3.2
38.79
38.48
u/l
0.01
48
466
14
105
1.40
0.45
1.9
1.4
19.59
21.24
nmol/l
0.20
14
90
11
79
1.45
0.43
1.5
1.6
—
—
—
0
0
29
246
1.28
0.42
3.8
2.6
—
—
—
0
0
35
304
1.26
0.42
3.8
2.7
0.00
0.00
estimate
—
8
58
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.4
—
84.00
—
0
5
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
35
308
1.24
0.37
4.2
3.7
0.00
0.00
estimate
—
7
56
6
87
0.67
0.35
1.3
1.5
—
—
—
0
0
35
310
1.23
0.34
3.8
2.8
0.00
0.00
estimate
—
7
54
70
668
1.33
0.33
15.9
10.1
25.17
21.12
mg/l
0.38
57
504
22
187
1.24
0.31
3.4
2.6
—
—
—
0
0
12
95
1.31
0.28
2.6
1.7
—
—
—
0
0
62
591
1.20
0.24
3.2
3.8
—
—
—
0
0
11
89
1.27
0.22
1.6
1.7
827273065.82
467.80
pmol/l
0.47
11
79
0
11
0.00
0.21
0.0
1.4
—
200.63
—
0
11
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
2.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
1.14
—
0
7
7
58
1.23
0.19
1.0
1.3
—
—
—
0
0
7
59
1.20
0.18
1.0
1.4
—
—
—
0
0
11
130
0.82
0.17
1.7
1.6
—
—
—
0
0
19
174
1.12
0.10
1.8
2.2
—
—
—
0
0
20
185
1.11
0.09
4.5
3.3
175.61
20.41
ng/l
0.57
12
94
5
61
0.81
0.08
2.4
2.2
336.60
381.64
nmol/l
—
5
56
7
64
1.10
0.08
8.4
6.4
—
—
—
0
0
19
179
1.08
0.05
3.6
2.6
53.58
54.21
u/l
0.04
19
166
17
161
1.07
0.03
1.8
2.0
—
—
—
0
0
18
187
0.95
0.01
1.9
1.8
—
—
—
0
0
30
295
1.03
0.00
2.3
2.7
79.09
81.77
ug/l
0.05
30
280
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.5
—
107.83
—
0
6
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
105.80
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
80
1.00
-0.00
1.4
1.7
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_MULTIPLE_CONGENITAL_EXOSTOSES – Multiple congenital exostoses
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).