Folliculitis decalvans

L12_FOLLICULITDECALV

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L66.2
  • Hospital discharge: ICD-9 7040F
  • Hospital discharge: ICD-8 70404
  • Cause of death: ICD-10 L66.2
  • Cause of death: ICD-9 7040F
  • Cause of death: ICD-8 70404

2 out of 7 registries used, show all original rules.

70

4. Check minimum number of events

None

70

5. Include endpoints

None

70

6. Filter based on genotype QC (FinnGen only)

70

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L66
Name in latin
Folliculitis decalvans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 658 239 416
Only index persons 549 217 332
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 35.79 40.86 32.78
Only index persons 33.67 39.68 29.74

-FinnGen-

Key figures

All Female Male
Number of individuals 70 37 33
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 35.30 34.68 36.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
64
Matched controls
641
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
70404
ICD-8 Finland
Diseases of hair and hair follicles, Folliculitis NUD
+∞
39.8
34
*
L66.2
ICD-10 Finland
Folliculitis decalvans
+∞
34.5
30
*
J01AA04
ATC
lymecycline; systemic
6.9
8.1
21
42
D10BA01
ATC
isotretinoin; oral
12.4
8.0
14
14
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
29.1
7.8
10
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
23
129
2.17
2.20
1.2
1.2
1.4
2.3
u/ml
—
7
38
13
59
2.48
1.98
1.4
1.7
—
—
—
0
0
24
153
1.87
1.56
2.2
2.9
11.8
53.9
mg/l
1.49
16
97
8
153
0.46
1.35
1.3
1.4
—
—
—
0
0
30
214
1.70
1.31
2.1
1.9
98.9
96.9
pmol/l
0.09
15
102
5
18
2.91
1.31
1.6
1.7
—
—
—
0
0
36
273
1.66
1.24
2.8
4.0
0.0
0.0
estimate
—
8
48
24
166
1.68
1.15
3.0
3.8
2.1
8.5
mg/mmol
1.32
17
101
11
59
2.03
1.15
1.4
1.6
—
—
—
0
0
35
269
1.60
1.11
3.8
5.7
0.0
0.0
estimate
—
8
50
18
116
1.74
1.10
1.0
1.4
2.4
2.6
g/l
—
10
72
35
271
1.58
1.06
2.7
3.9
0.0
0.0
estimate
—
5
52
0
29
0.00
1.00
0.0
5.2
—
—
—
0
0
7
36
2.05
1.00
1.3
1.3
—
—
—
0
0
8
43
1.97
0.91
1.0
1.1
—
—
—
0
0
19
133
1.59
0.85
4.1
6.1
—
—
—
0
0
5
24
2.16
0.76
1.6
1.3
—
—
—
0
0
5
25
2.07
0.74
2.6
4.8
—
—
—
0
0
7
41
1.78
0.72
4.6
3.5
81.4
76.8
ng/l
—
7
36
5
27
1.92
0.70
3.2
2.2
—
—
—
0
0
9
139
0.60
0.69
1.1
1.5
1.2
1.0
mg/l
—
9
112
5
28
1.84
0.67
1.0
1.1
—
—
—
0
0
0
20
0.00
0.61
0.0
1.6
—
—
—
0
0
29
236
1.39
0.61
3.2
7.0
1.2
1.2
inr
—
9
68
20
152
1.44
0.61
2.6
3.7
—
—
—
0
0
11
77
1.51
0.49
2.3
2.2
15.5
12.9
umol/l
0.84
11
70
18
140
1.38
0.48
3.2
3.9
0.0
0.0
estimate
—
8
50
10
69
1.52
0.47
1.9
1.5
—
—
—
0
0
14
105
1.42
0.45
1.1
1.3
26.0
8.4
u/ml
—
9
44
8
55
1.51
0.45
1.4
1.3
—
—
—
0
0
25
209
1.31
0.42
2.4
3.8
—
—
—
0
0
0
15
0.00
0.42
0.0
1.1
—
1.9
—
0
9
0
15
0.00
0.42
0.0
1.3
—
11.0
—
0
9
0
15
0.00
0.42
0.0
2.7
—
130.2
—
0
9
0
15
0.00
0.42
0.0
1.1
—
780.2
—
0
15
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
9
67
1.39
0.40
1.1
1.3
—
—
—
0
0
9
68
1.37
0.40
1.2
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
14
177
0.74
0.39
3.6
2.2
—
—
—
0
0
15
119
1.33
0.35
2.9
4.0
—
—
—
0
0
7
99
0.67
0.33
1.1
1.8
—
—
—
0
0
40
363
1.24
0.33
3.8
4.1
—
14.2
—
0
6
15
122
1.29
0.30
1.2
1.6
20.6
21.3
nmol/l
0.07
15
98
10
77
1.35
0.28
1.8
1.9
—
—
—
0
0
9
73
1.27
0.27
2.7
2.2
2.2
2.4
g/l
—
9
63
25
222
1.20
0.23
2.3
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
91.2
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
6
47
1.30
0.21
3.0
3.8
1.2
1.2
mmol/l
—
6
41
60
578
1.27
0.21
12.7
12.8
22.2
21.0
mg/l
0.09
52
443
0
13
0.00
0.21
0.0
3.2
—
16.5
—
0
6
0
13
0.00
0.21
0.0
5.4
—
29.3
—
0
8
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
3.7
—
0
13
35
323
1.17
0.21
4.1
5.6
10.6
11.3
umol/l
0.28
35
310
54
516
1.20
0.20
12.7
13.2
40.5
40.1
%
0.12
40
382
21
234
0.85
0.18
2.4
4.1
15.3
28.9
ng/l
1.77
11
163
11
130
0.82
0.17
2.5
4.5
—
—
—
0
0
8
72
1.13
0.16
1.4
1.3
—
—
—
0
0
63
611
1.31
0.15
15.3
15.9
74.8
76.4
umol/l
0.16
63
611
14
123
1.17
0.14
2.5
3.0
0.8
0.8
ug/l
—
7
81
41
394
1.10
0.09
3.4
3.8
—
—
—
0
0
24
225
1.10
0.09
2.5
2.8
—
—
—
0
0
59
577
1.14
0.09
4.9
4.5
5.9
5.9
mmol/l
0.11
54
530
5
60
0.82
0.08
1.2
1.6
—
—
—
0
0
21
196
1.10
0.08
3.4
3.8
95.5
56.8
e6/l
0.17
16
133
8
73
1.11
0.08
1.1
1.6
—
—
—
0
0
39
376
1.08
0.07
4.8
4.0
—
—
—
0
0
62
606
1.20
0.07
11.1
11.9
—
—
—
0
0
14
152
0.90
0.07
4.5
5.8
—
—
—
0
0
27
257
1.08
0.07
8.2
10.5
0.0
0.0
e9/l
0.00
22
199
12
109
1.12
0.06
1.1
1.3
30.7
31.6
iu/ml
—
6
36
17
182
0.91
0.06
3.4
3.7
—
—
—
0
0
16
149
1.10
0.06
2.6
3.0
—
—
—
0
0
19
179
1.08
0.05
3.3
5.1
—
—
—
0
0
16
151
1.08
0.03
2.2
2.5
352.8
8641.0
umol/l
1.31
16
135
16
161
0.99
0.00
3.9
3.1
—
—
—
0
0
5
51
0.98
0.00
4.0
4.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
5
55
0.90
0.00
4.0
2.9
—
—
—
0
0
0
9
0.00
0.00
0.0
2.1
—
1.6
—
0
9
0
6
0.00
0.00
0.0
1.2
—
41.3
—
0
6
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
2.7
—
14.8
—
0
9
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
6
67
0.89
0.00
1.2
2.0
300.5
354.3
nmol/l
—
6
59
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
54
0.92
0.00
2.8
3.5
2.2
13.2
ug/l
—
5
39
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
331.2
—
0
6

Mortality – FinRegistry

Association

Association between endpoint L12_FOLLICULITDECALV and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_FOLLICULITDECALV.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: L12_FOLLICULITDECALV – Folliculitis decalvans

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data