Takayasu arteritis: Takayasu arteritis (TAK) is a rare inflammatory large-vessel vasculitis primarily affecting the aorta and its major branches, but also other large vessels, causing stenosis, occlusion, or aneurysm.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
69 |
4. Check minimum number of eventsNone |
69 |
5. Include endpointsNone |
69 |
6. Filter based on genotype QC (FinnGen only) |
69 |
Control definitions (FinnGen only)
- Control exclude
- M13_SYSTCONNECT
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M31
- Name in latin
- Syndroma arcus aortae
Similar endpoints
↥List of similar endpoints to
Aortic arch syndrome [Takayasu]
based on the number of shared cases.
Similar with more cases:
- Other necrotizing vasculopathies (FG)
- Other necrotizing vasculopathies
- Systemic connective tissue disorders
- Autoimmune diseases related-to ILD
- Finngen Rheumatological endpoints
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 358 | 271 | 81 |
| Only index persons | 287 | 221 | 66 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 55.89 | 56.33 | 53.98 |
| Only index persons | 54.26 | 55.37 | 50.54 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 69 | 53 | 16 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | 48.35 | 49.08 | 45.93 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 58
- Matched controls
- 578
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M31.4
ICD-10 Finland
Aortic arch syndrome [Takayasu]
+∞
80.4
57
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
30.8
24.8
35
27
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
24.2
20.7
31
26
H02AB06
ATC
prednisolone; systemic
13.3
15.3
50
185
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
8.1
12.5
40
124
GD1AA
NOMESCO Finland
Thorax X-ray examination
7.3
11.4
41
143
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
16.8
11.3
18
15
L04AX01
ATC
azathioprine; systemic
17.9
9.3
14
10
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
+∞
8.5
8
*
PAW37
NOMESCO Finland
Biopsy of temporal artery
+∞
8.5
8
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
9.5
8.2
17
24
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.7
8.2
20
37
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
22.1
8.0
11
6
M35.3
ICD-10 Finland
Polymyalgia rheumatica
29.6
7.9
10
*
M34.1
ICD-10 Finland
CR(E)ST syndrome
+∞
7.4
7
*
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
+∞
7.4
7
*
4467A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Takayasu's disease
+∞
7.4
7
*
ZX120
NOMESCO Finland
Intravenous
8.8
7.1
15
22
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
10.8
7.0
13
15
M05BA04
ATC
alendronic acid; oral
9.3
6.9
14
19
TPH04
NOMESCO Finland
Cathetrisation of vein
5.0
6.7
24
71
I77.6
ICD-10 Finland
Arteritis, unspecified
78.1
6.6
7
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
17
13
17.03
18.35
1.1
1.2
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
32
66
8.18
16.75
1.6
1.4
titre
960.0
409.2
—
7
13
(42870588) Differential panel, method unspecified - Blood
51
169
8.73
16.68
20.2
4.6
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
59
267
9.35
12.74
9.0
8.4
mmol/l
1.2
1.2
1.58
49
225
(3018418) pH of Serum or Plasma
45
165
5.97
12.13
4.1
3.5
ph
7.4
7.4
—
8
28
(3023368) Bacteria identified in Blood by Culture
39
130
5.60
11.66
5.3
4.7
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
14
17
10.08
11.02
1.5
1.3
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
56
294
5.80
8.70
5.8
4.5
estimate
0.0
0.0
—
10
55
(3035350) Ketones [Presence] in Urine by Test strip
56
296
5.73
8.57
3.9
3.2
estimate
0.0
0.0
—
10
56
(3009261) Glucose [Presence] in Urine by Test strip
56
300
5.60
8.32
4.0
3.3
estimate
0.0
0.0
—
10
53
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
12
17
8.33
8.28
1.8
1.1
g/l
0.2
0.2
0.33
12
17
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
12
17
8.33
8.28
1.8
1.1
g/l
1.2
1.2
0.01
12
17
(3037467) Urinalysis macro (dipstick) panel - Urine
64
414
8.52
8.27
8.8
4.0
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
10
12
9.58
7.78
1.6
1.1
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
43
199
4.08
7.55
10.1
7.3
inr
1.2
1.2
0.11
12
59
(3015736) pH of Urine
47
235
4.14
7.30
3.7
2.8
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
45
228
3.80
6.65
3.7
2.4
nmol/l
78.8
75.0
0.41
45
206
(3011397) Hemoglobin [Presence] in Urine by Test strip
33
138
3.67
6.52
4.2
3.0
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
10
16
7.14
6.14
2.0
1.3
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
40
195
3.50
6.14
6.4
3.4
e6/l
51.4
51.4
0.00
29
134
(3021879) Hepatitis B virus core Ab [Presence] in Serum
16
41
4.78
6.11
1.3
1.5
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
8
5
17.81
5.55
1.3
1.0
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
10
18
6.33
5.50
1.5
1.4
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
37
187
3.11
5.10
4.2
3.0
u/l
31.4
28.0
0.48
37
176
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
36
184
3.00
4.79
5.5
2.6
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
13
34
4.48
4.79
1.2
1.2
—
—
—
0
0
(3044889) 12 lead EKG panel
58
390
4.06
4.78
4.8
3.3
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
40
221
2.93
4.56
5.5
5.1
g/l
33.6
35.5
1.13
40
214
(3012095) Magnesium [Moles/volume] in Serum or Plasma
22
89
3.16
4.34
3.0
3.2
mmol/l
0.8
0.8
0.25
22
82
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
20
77
3.25
4.27
4.1
2.4
e6/l
0.5
1.1
0.88
15
40
(40760892) CBC W Ordered Manual Differential panel - Blood
28
132
2.89
4.22
11.4
4.1
—
—
—
0
0
(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis
8
10
8.86
4.18
1.8
1.1
g/l
0.1
0.0
—
8
10
(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis
8
10
8.86
4.18
1.8
1.1
g/l
0.0
0.0
—
8
10
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
8
10
8.86
4.18
1.0
1.1
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
7
7
10.94
4.11
5.1
2.6
e9/l
4.6
7.8
—
7
7
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
7
7
10.94
4.11
5.1
4.7
%
60.1
70.3
—
7
7
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
7
7
10.94
4.11
1.1
1.6
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
16
55
3.49
4.06
1.4
1.9
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
8
11
8.05
3.98
1.3
1.3
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
30
151
2.75
3.95
5.1
2.4
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
25
115
2.84
3.90
2.0
1.4
g/l
2.5
3.1
0.49
20
62
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
8
12
7.37
3.79
1.3
1.1
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
8
12
7.37
3.79
1.3
1.3
—
—
—
0
0
(3012110) Lysozyme [Mass/volume] in Serum or Plasma
8
12
7.37
3.79
1.8
2.1
mg/l
9.2
10.0
—
8
12
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
7
9
8.49
3.65
1.9
1.1
g/l
0.0
0.0
—
7
9
(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis
7
9
8.49
3.65
1.9
1.1
g/l
0.0
0.0
—
7
9
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
22
98
2.83
3.61
6.9
4.0
ng/l
87.1
41.9
0.31
15
71
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
6
7
9.24
3.33
1.2
1.0
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
6
7
9.24
3.33
1.2
1.0
—
—
—
0
0
(4306422)
7
11
6.93
3.27
1.0
1.1
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
18
76
2.85
3.22
4.7
2.5
e6/l
2.2
4.0
0.39
13
39
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
11
34
3.66
3.21
1.7
1.6
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
6
8
8.07
3.12
1.2
1.8
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
21
98
2.64
3.11
1.5
1.6
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
7
12
6.35
3.10
1.6
1.5
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
23
113
2.55
3.07
1.3
1.2
u/ml
51.5
7.1
—
9
50
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
14
54
3.00
2.92
1.9
1.6
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
8
18
4.88
2.89
1.4
1.3
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
14
55
2.94
2.82
1.9
1.6
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
5
6
8.85
2.79
1.0
1.7
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
54
400
2.61
2.79
5.6
4.2
—
423.9
—
0
8
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
22
111
2.44
2.75
1.3
1.3
iu/ml
21.3
38.5
—
8
34
(40758558) Short blood count panel - Blood
27
151
2.29
2.68
17.0
6.9
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
5
7
7.58
2.59
1.2
1.7
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
16
72
2.59
2.51
1.1
1.2
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
22
118
2.27
2.37
1.6
2.1
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
5
9
5.89
2.25
1.2
1.1
—
—
—
0
0
(4268621)
5
9
5.89
2.25
2.2
1.9
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
17
83
2.39
2.25
2.1
1.7
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
16
76
2.44
2.24
1.6
1.5
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
11
43
2.85
2.22
4.5
4.1
ng/l
80.3
69.7
0.16
11
37
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
32
205
2.05
2.18
4.9
3.0
ng/l
175.1
37.7
0.50
21
126
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
8
25
3.48
2.17
13.6
30.4
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
7
20
3.77
2.11
17.4
4.4
mmol/l
25.1
25.1
—
7
20
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
5
10
5.29
2.10
1.0
1.6
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
6
15
4.27
2.08
1.3
1.5
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
0
53
0.00
1.97
0.0
2.0
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
35
240
1.93
1.90
4.1
3.1
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
29
187
1.95
1.88
2.5
2.1
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
23
137
2.02
1.86
2.4
2.1
—
—
—
0
0
(3019060) Gas panel - Arterial blood
8
29
2.98
1.86
6.0
21.0
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
5
12
4.40
1.85
1.0
1.5
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
10
41
2.68
1.85
3.9
4.6
kpa
5.9
5.7
—
10
41
(3012516) Albumin [Mass/volume] in Urine
24
146
1.99
1.83
3.4
2.8
mg/l
1690.0
43.8
0.48
17
87
(3042936) Bacteria identified in Isolate by Culture
17
91
2.15
1.80
2.8
2.5
—
—
—
0
0
(3000991) Gas panel - Venous blood
8
30
2.88
1.79
17.9
10.9
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
0
46
0.00
1.78
0.0
1.9
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
25
156
1.94
1.77
3.6
3.8
mg/mmol
8.8
8.2
0.05
16
93
(3029937) Albumin [Presence] in Urine by Test strip
26
165
1.92
1.75
4.3
3.2
estimate
0.0
0.0
—
9
54
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
22
132
1.98
1.73
2.6
1.6
mg/l
0.8
1.1
0.69
16
100
(3009542) Hematocrit [Volume Fraction] of Blood
62
535
2.56
1.70
37.0
14.0
%
39.3
39.7
0.25
46
410
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
11
50
2.43
1.67
2.2
2.9
u/l
21.4
27.6
0.96
11
40
(3004119) Hemoglobin [Mass/volume] in Venous blood
8
32
2.69
1.65
3.4
4.4
g/l
123.4
127.1
—
8
32
(3025941) Bacteria identified in Stool by Culture
8
32
2.69
1.65
1.3
1.3
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
5
15
3.51
1.55
1.0
1.5
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
5
15
3.51
1.55
2.2
2.5
—
—
—
0
0
(40768443) Skin Pathology biopsy report
6
21
3.03
1.54
1.8
1.4
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
6
22
2.89
1.47
2.5
2.3
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
6
22
2.89
1.47
3.8
1.5
%
93.0
94.9
—
6
22
(40761536) Microorganisms panel - Urine sediment
10
47
2.32
1.41
2.5
3.5
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
22
141
1.82
1.40
5.0
2.9
kg/l
1.0
1.0
—
5
16
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
6
23
2.76
1.40
21.7
11.8
%
0.8
0.8
—
6
23
(3014007) Fractional oxyhemoglobin in Arterial blood
6
23
2.76
1.40
21.7
11.9
%
95.0
92.2
—
6
23
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
19
117
1.86
1.36
1.4
1.6
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
6
24
2.64
1.33
21.7
11.4
%
2.0
2.0
—
6
24
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
29
205
1.72
1.32
2.5
1.8
pmol/l
91.5
104.5
0.85
16
101
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
6
25
2.53
1.27
1.2
1.4
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
25
172
1.71
1.24
3.0
2.9
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
10
50
2.17
1.23
2.2
2.5
e9/l
6.8
3.9
—
10
44
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
61
544
2.04
1.22
32.7
12.0
ml/min/173m2
83.6
84.9
0.16
55
440
(3007853) Bacteria identified in Skin by Aerobe culture
12
66
1.99
1.18
2.9
1.7
—
—
—
0
0
(40761535) Cells panel - Urine sediment
8
40
2.13
1.16
5.5
2.8
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
38
297
1.62
1.14
4.5
4.3
—
—
—
0
0
(3013512) EKG study
25
176
1.66
1.13
6.1
3.2
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
5
21
2.48
1.11
4.4
2.1
%
130.8
202.5
—
5
21
(3026008) Bacteria identified in Urine by Culture
26
188
1.61
1.05
4.5
2.8
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
10
55
1.96
0.98
1.4
1.0
—
—
—
0
0
(3002256) Pathology report gross observation
12
71
1.84
0.96
1.2
1.2
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
53
460
1.66
0.94
5.0
4.2
pmol/l
14.6
14.7
0.01
53
424
(3003327) Ova and parasites identified in Stool by Light microscopy
6
29
2.17
0.92
1.7
1.6
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
6
29
2.17
0.92
1.3
1.6
—
—
—
0
0
(3000492) Spirometry study
8
45
1.88
0.88
1.6
1.2
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
12
74
1.75
0.85
1.2
1.7
—
—
—
0
0
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
0
24
0.00
0.81
0.0
1.6
—
325.1
—
0
14
(3027273) Bicarbonate [Moles/volume] in Venous blood
5
24
2.17
0.76
2.8
3.8
mmol/l
25.3
24.3
—
5
24
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
5
27
1.92
0.70
1.8
1.6
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
60
553
1.65
0.70
6.0
4.9
mu/l
1.7
1.8
0.23
60
512
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
46
401
1.44
0.67
3.8
2.8
u/l
61.0
40.0
1.33
41
384
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
13
89
1.57
0.63
1.8
3.0
mmol/l
2.5
2.5
0.12
13
83
(3019225) pH of Specimen
8
52
1.61
0.62
5.3
4.0
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
6
34
1.84
0.60
5.0
2.4
kpa
4.8
4.4
—
6
34
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
22
0.00
0.60
0.0
2.1
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
0
23
0.00
0.59
0.0
1.7
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
9
60
1.57
0.57
4.2
3.3
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
29
241
1.35
0.53
2.1
2.0
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
5
80
0.60
0.49
4.8
4.5
%
36.8
33.0
—
5
52
(3022145) Colonoscopy Study observation
11
77
1.51
0.49
1.4
1.3
—
—
—
0
0
(3022621) pH of Urine by Test strip
7
50
1.44
0.46
1.6
2.4
—
—
—
0
0
(3009343) pH of Capillary blood
5
31
1.66
0.44
4.6
1.5
—
7.4
—
0
5
(3008898) HLA-B27 [Presence]
5
33
1.55
0.42
1.0
1.0
—
—
—
0
0
(3051387) C reactive protein [Mass/volume] in Capillary blood
0
15
0.00
0.42
0.0
5.9
—
31.6
—
0
9
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
18
0.00
0.40
0.0
2.1
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
9
67
1.39
0.40
1.2
1.5
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
18
218
0.76
0.38
3.2
2.8
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
39
428
0.80
0.35
3.9
3.5
—
—
—
0
0
(4010399)
5
37
1.38
0.24
1.4
1.4
—
—
—
0
0
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
5
39
1.30
0.23
5.8
2.8
pmol/l
4.8
4.4
—
5
34
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
14
0.00
0.20
0.0
1.9
—
15.0
—
0
14
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
5
65
0.75
0.18
1.2
1.4
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
5
43
1.18
0.10
1.0
1.4
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
6
57
1.06
0.09
3.0
1.8
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
6
71
0.83
0.08
11.2
5.7
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
11
120
0.90
0.05
1.9
1.3
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
18
176
1.03
0.00
1.4
1.6
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3001788) Aldosterone [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
299.6
—
0
8
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
14.0
—
0
5
(4035726)
5
51
0.98
0.00
1.8
1.4
—
—
—
0
0
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(44806118)
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(4211845)
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3006270) Folate [Moles/volume] in Blood
0
5
0.00
0.00
0.0
1.2
—
280.6
—
0
5
(44790047)
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
13.1
—
788.6
—
0
7
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(4146454)
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
3.5
—
57.3
—
0
6
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(44790048)
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
5
59
0.84
0.00
1.0
1.6
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
18.1
—
1442.9
—
0
7
(44790049)
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
0
9
0.00
-0.00
0.0
3.6
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
9
0.00
-0.00
0.0
2.7
—
2.2
—
0
9
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_TAKAYASU and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have M13_TAKAYASU.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: M13_TAKAYASU – Aortic arch syndrome [Takayasu]
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data