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Melanoma in situ of upper limb, including shoulder

CD2_INSITU_MELANOMA_UPPERLIMB

melanoma: A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D03.6&
  • Cause of death: ICD-10 D03.6&

2 out of 7 registries used, show all original rules.

268

4. Check minimum number of events

None

268

5. Include endpoints

None

268

6. Filter based on genotype QC (FinnGen only)

258

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D03
Name in latin
Melanoma in situ regionis deltoideae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 258 155 103
Unadjusted period prevalence (%) 0.05 0.05 0.05
Median age at first event (years) 69.12 67.54 71.51

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
268
Matched controls
2680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
4503599627370496.0
307.7
267
*
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
231.1
307.7
176
22
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
49.2
92.1
55
14
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
13.8
78.7
86
89
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
16.0
75.1
72
60
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
9.6
66.6
100
156
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
174.1
65.3
66
5
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
13.7
60.7
63
59
L57.0
ICD-10 Finland
Actinic keratosis
6.8
48.6
102
222
R23.8
ICD-10 Finland
Other and unspecified skin changes
5.9
45.4
121
326
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
7.8
43.7
72
121
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.0
33.6
71
151
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
11.4
32.5
36
36
TQW99
NOMESCO Finland
Other minor procedure on skin
7.0
29.4
50
85
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
12.4
29.0
30
27
S82
ICPC
Naevus/mole
4.9
28.6
79
210
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
5.4
26.1
60
136
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
10.7
24.5
28
29
ZZR00
NOMESCO Finland
Flap of skin
10.3
23.9
28
30
C43.62
ICD-10 Finland
Malignant melanoma of upper extremity including shoulder: 'superficial spreading' type
59.7
23.5
27
5
S18
ICPC
Laceration/cut
3.6
22.3
180
968
TQW40, ,
SPAT
5.1
19.8
46
104
D06BB10
ATC
imiquimod; topical
5.5
18.2
38
78
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
34.0
17.3
22
7
ZXC50
NOMESCO Finland
Cryotherapy
6.7
17.2
29
48
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
6.2
17.2
31
55
C43.60
ICD-10 Finland
Malignant melanoma of the upper extremity including the shoulder without histology
180.8
16.7
17
*
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
26.5
16.3
22
9
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
7.2
16.0
25
38
SPAT1153
SPAT
Removal of sutures
2.8
15.6
126
638
XQ848
NOMESCO Finland
Dermatological photography
7.2
15.6
24
36
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
4.6
15.0
39
96
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
158.3
14.6
15
*
D22
ICD-10 Finland
Melanocytic naevi
6.2
14.4
26
46
D03.5
ICD-10 Finland
Melanoma in situ of trunk
45.1
14.3
17
*
8720/3-C44.6
ICD-O-3
Malignant melanoma, NOS, of skin of upper limb and shoulder
79.3
13.7
15
*
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
12.4
13.6
24
21
L82
ICD-10 Finland
Seborrhoeic keratosis
2.9
13.4
82
354
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
11.3
12.5
23
22
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
22.6
12.2
17
8
S77
ICPC
Malignant neoplasm of skin
15.6
12.0
19
13
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
5.5
12.0
24
47
8720/2-C44.6
ICD-O-3
Melanoma in situ of skin of upper limb and shoulder
+∞
11.5
11
*
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
45.3
11.0
13
*
XQ845
NOMESCO Finland
Dermatoscopy
11.3
10.5
19
18
C43.6
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of upper limb, including shoulder
41.7
10.0
12
*
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
27.2
9.9
13
5
C43.69
ICD-10 Finland
Malignant melanoma of the upper extremity including shoulder other or unspecified histology
57.1
9.7
11
*
C43
ICD-10 Finland
Malignant melanoma of skin
31.3
9.5
12
*
PJA12
NOMESCO Finland
Sentinel node biopsy
3.2
9.1
40
141
D03.7
ICD-10 Finland
Melanoma in situ of lower limb, including hip
92.9
8.5
9
*
C43.61
ICD-10 Finland
Malignant melanoma of the upper extremity including the shoulder originating in lentigo maligna
+∞
8.4
8
*
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
12.2
8.2
14
12
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
22.8
8.1
11
5
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
13.6
8.0
13
10
S29
ICPC
Skin symptom/complaint other
2.3
7.2
66
336
WX110
NOMESCO Finland
Infiltration anesthesia
2.1
7.0
191
1449
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
14.3
6.9
11
8
8743/3-C44.9
ICD-O-3
Low cumulative sun damage melanoma of skin, NOS
23.2
6.7
9
*
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
23.2
6.7
9
*
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
6.0
6.6
17
30
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
5.8
6.4
17
31
127
Kela drug reimbursment
Transplant complication
11.4
6.4
11
10
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
12.9
6.1
10
8
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
12.9
6.1
10
8
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
12.9
6.1
10
8
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
6.3
6.1
15
25
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.6
6.0
37
156

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
140
296
8.81
71.89
2.1
1.3
—
—
—
0
0
219
918
8.58
51.15
4.1
2.2
—
—
—
0
0
61
219
3.31
13.72
1.7
1.4
—
—
—
0
0
34
98
3.83
10.56
1.4
1.2
—
—
—
0
0
168
1170
2.17
8.44
6.6
6.0
1.22
1.22
mmol/l
0.56
139
988
43
173
2.77
7.72
2.9
3.4
74.40
80.46
ng/l
0.30
30
150
155
1087
2.01
7.17
6.4
5.2
1.22
1.22
mmol/l
0.58
137
987
47
216
2.43
6.42
3.6
4.0
—
—
—
0
0
260
2401
3.78
4.73
25.0
22.3
39.92
39.83
%
0.08
249
2243
115
808
1.74
4.62
3.9
3.4
2.34
2.35
mmol/l
0.45
90
713
247
2197
2.59
4.46
5.5
5.2
2.74
2.68
mmol/l
0.40
210
1986
203
1684
1.85
4.44
4.8
4.0
11.97
12.96
mm/h
0.39
180
1542
135
1006
1.69
4.29
6.9
6.0
—
—
—
0
0
241
2134
2.28
4.16
5.2
4.6
1.52
1.49
mmol/l
0.38
201
1930
235
2062
2.13
4.14
6.3
6.0
38.77
40.33
mmol/mol
2.74
200
1905
242
2149
2.30
4.11
5.0
4.6
4.68
4.60
mmol/l
0.54
205
1956
160
1278
1.63
3.65
8.1
9.4
4.01
4.13
e9/l
0.29
128
1123
103
740
1.64
3.61
5.1
3.8
7.40
7.40
ph
0.21
22
148
254
2328
2.74
3.58
12.4
10.6
24.56
24.44
u/l
0.05
239
2232
128
974
1.60
3.53
10.6
10.0
0.00
0.00
e9/l
0.52
101
794
128
974
1.60
3.53
6.0
5.3
0.63
0.65
%
0.17
122
903
240
2152
2.10
3.51
5.3
4.9
5.82
6.01
mmol/l
1.43
198
1946
138
1079
1.58
3.33
5.9
5.3
0.59
0.59
e9/l
0.11
109
936
229
2031
1.88
3.32
6.5
4.8
1.86
2.56
mu/l
0.61
202
1824
142
1121
1.57
3.26
6.3
5.8
0.17
0.19
e9/l
0.48
113
987
57
359
1.75
3.23
1.3
1.3
25.94
33.20
iu/ml
0.36
14
124
100
730
1.59
3.21
2.8
2.3
—
—
—
0
0
252
2318
2.46
3.21
19.5
17.9
81.14
78.16
umol/l
0.72
252
2318
138
1085
1.56
3.21
5.9
5.3
0.04
0.04
e9/l
0.26
110
939
129
1006
1.54
3.07
6.0
5.4
2.65
2.80
%
0.31
123
938
134
1057
1.54
3.00
2.9
2.5
—
—
—
0
0
230
2060
1.82
2.98
4.7
4.1
1.28
1.27
mmol/l
0.04
187
1848
129
1013
1.53
2.93
6.2
5.7
8.90
8.72
%
0.34
122
948
139
1110
1.52
2.92
6.0
5.4
1.81
2.00
e9/l
0.79
113
989
193
1661
1.58
2.83
5.3
3.9
15.10
14.86
pmol/l
0.67
164
1480
240
2191
1.91
2.74
16.4
15.1
19.30
23.86
mg/l
1.25
204
1750
130
1033
1.50
2.74
6.1
5.5
26.66
27.28
%
0.31
124
968
129
1024
1.50
2.73
5.8
5.3
58.51
57.37
%
0.62
123
959
82
595
1.54
2.63
3.5
2.7
4902.53
6420.95
umol/l
0.12
74
504
83
604
1.54
2.62
1.5
1.6
1.26
1.35
mmol/l
0.50
66
505
203
1780
1.58
2.62
8.6
7.3
74.09
80.64
u/l
2.03
185
1660
245
2259
1.99
2.60
15.7
14.1
—
—
—
0
0
59
399
1.61
2.54
3.6
3.1
0.78
0.77
ug/l
0.02
38
262
248
2302
2.04
2.48
20.2
17.6
3.98
3.99
mmol/l
0.17
242
2232
94
713
1.49
2.42
4.1
4.1
—
—
—
0
0
247
2295
1.97
2.38
19.9
17.5
139.80
139.67
mmol/l
0.40
242
2227
11
39
2.90
2.37
2.8
3.4
55.64
61.87
%
1.29
11
39
120
961
1.45
2.32
2.2
2.0
92.50
95.32
pmol/l
0.19
50
469
53
358
1.60
2.29
5.1
3.2
0.85
0.81
mmol/l
0.97
47
336
79
585
1.50
2.27
1.6
1.6
23.20
21.84
nmol/l
0.23
60
482
8
26
3.14
2.03
1.5
1.2
—
—
—
0
0
10
39
2.62
1.96
2.3
2.8
3.86
5.00
e9/l
—
10
39
5
11
4.61
1.95
1.2
1.2
—
—
—
0
0
176
1542
1.41
1.92
5.0
4.5
—
—
—
0
0
7
23
3.10
1.81
1.6
1.5
—
—
—
0
0
135
1139
1.37
1.80
22.0
14.4
1.47
1.27
inr
1.24
41
319
172
1511
1.39
1.78
5.2
4.8
19.00
3388.09
e6/l
—
5
34
40
271
1.56
1.72
2.1
1.4
—
—
—
0
0
122
1022
1.36
1.67
5.3
4.1
35.32
35.23
g/l
0.07
109
958
6
19
3.21
1.67
1.8
1.3
—
—
—
0
0
47
333
1.50
1.65
1.4
1.3
14.61
12.06
u/ml
0.08
13
124
5
14
3.62
1.62
1.0
1.6
—
—
—
0
0
6
20
3.04
1.59
1.0
2.5
—
—
—
0
0
47
338
1.47
1.54
2.2
1.8
—
—
—
0
0
88
710
1.36
1.51
2.6
2.0
260.19
196.30
u/l
0.32
80
661
6
22
2.77
1.44
1.0
1.6
274.00
272.56
mosm/kgh2o
—
6
16
7
29
2.45
1.40
2.7
1.3
—
—
—
0
0
101
841
1.32
1.39
5.0
3.8
77.26
69.91
e6/l
0.06
73
600
156
1381
1.31
1.37
3.8
3.0
47.82
48.33
u/l
0.03
141
1282
80
645
1.34
1.36
3.7
3.0
—
—
—
0
0
108
910
1.31
1.36
3.1
2.7
174.32
123.70
ug/l
1.05
96
823
35
244
1.50
1.34
1.7
1.7
—
—
—
0
0
6
132
0.44
1.32
1.0
1.3
—
—
—
0
0
81
660
1.33
1.28
3.8
3.1
1.09
0.54
e6/l
0.28
59
495
88
727
1.31
1.26
4.1
3.2
41.11
142.38
e6/l
0.57
65
561
6
25
2.43
1.25
1.7
1.6
—
—
—
0
0
20
124
1.66
1.25
2.5
2.5
—
—
—
0
0
37
266
1.45
1.23
1.1
1.3
—
—
—
0
0
173
1569
1.29
1.18
4.0
4.1
—
—
—
0
0
0
34
0.00
1.16
0.0
3.0
—
—
—
0
0
0
35
0.00
1.16
0.0
2.9
—
106.23
—
0
35
0
35
0.00
1.16
0.0
2.9
—
3.98
—
0
35
60
479
1.33
1.09
3.2
2.9
2.46
2.46
mmol/l
0.19
52
423
7
32
2.22
1.09
1.0
1.0
—
—
—
0
0
10
178
0.54
1.08
2.9
2.6
3.94
4.34
kpa
—
10
170
50
389
1.35
1.07
3.0
2.9
3.09
2.61
e6/l
0.16
25
208
9
46
1.99
1.04
6.8
2.3
—
—
—
0
0
9
46
1.99
1.04
4.8
2.5
—
—
—
0
0
7
34
2.09
1.03
2.1
1.6
—
—
—
0
0
7
34
2.09
1.03
1.0
1.0
—
—
—
0
0
82
688
1.28
1.03
3.9
2.9
6.88
7.22
mmol/l
0.30
63
573
38
494
0.73
1.00
5.1
4.4
1.02
1.02
kg/l
—
8
69
5
23
2.20
0.98
1.2
1.1
—
—
—
0
0
7
36
1.97
0.97
1.0
1.2
8.63
9.97
u/l
—
7
30
89
759
1.26
0.97
3.0
3.2
—
—
—
0
0
6
27
2.25
0.94
1.2
1.0
—
—
—
0
0
27
195
1.43
0.90
5.2
4.0
—
—
—
0
0
79
670
1.25
0.90
3.8
3.0
18.21
138.98
mg/l
0.70
43
435
12
71
1.72
0.90
1.4
1.3
—
—
—
0
0
69
576
1.27
0.90
2.4
2.0
2.97
3.22
mg/l
0.43
49
492
10
56
1.82
0.89
3.3
2.9
7.41
7.43
ph
—
10
49
82
700
1.25
0.88
6.3
5.3
9.56
2.51
ug/l
0.44
71
621
8
45
1.80
0.85
4.0
2.1
—
—
—
0
0
7
123
0.56
0.80
4.0
3.9
—
—
—
0
0
138
1254
1.21
0.80
6.8
6.0
10.31
11.35
umol/l
1.26
129
1184
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
17
116
1.50
0.76
1.4
1.9
1.23
1.57
g/l
0.61
12
100
68
578
1.24
0.76
6.0
7.1
—
—
—
0
0
5
24
2.10
0.75
1.2
1.2
—
—
—
0
0
81
703
1.22
0.74
4.9
3.6
3.64
7.98
mg/mmol
1.87
43
442
5
28
1.80
0.66
3.8
3.1
4.70
3.29
nmol/l
—
5
28
5
29
1.74
0.64
1.2
1.2
0.78
0.48
nmol/l
—
5
24
0
22
0.00
0.59
0.0
2.8
—
—
—
0
0
14
195
0.70
0.58
1.9
1.6
—
—
—
0
0
26
203
1.31
0.58
2.0
2.6
56.86
70.05
e9/l
2.17
16
157
146
1364
1.15
0.54
4.6
4.2
6.54
6.65
mmol/l
0.25
139
1276
14
100
1.42
0.53
2.4
3.1
—
—
—
0
0
12
84
1.45
0.50
2.4
3.2
0.14
0.16
g/l
—
5
25
58
507
1.18
0.50
2.8
1.7
0.94
1.27
mg/l
0.83
44
389
38
319
1.22
0.49
1.2
1.2
—
—
—
0
0
57
498
1.18
0.49
3.8
2.6
6.66
4.94
e6/l
0.31
52
449
7
47
1.50
0.48
1.0
1.1
3.81
3.90
mmol/l
—
7
42
52
453
1.18
0.47
4.8
3.9
468.63
197.42
ng/l
0.47
46
374
5
81
0.61
0.46
2.2
3.9
67.92
151.63
mg/l
—
5
62
16
208
0.75
0.46
11.0
5.3
1.29
1.41
mmol/l
0.20
16
202
53
464
1.18
0.45
1.2
1.2
0.88
1.23
u/ml
0.53
17
124
10
140
0.70
0.44
1.5
1.8
0.90
1.48
g/l
—
10
125
25
203
1.26
0.44
1.6
1.5
—
—
—
0
0
5
32
1.57
0.42
2.0
2.8
—
—
—
0
0
0
17
0.00
0.41
0.0
2.1
—
8.41
—
0
17
17
133
1.30
0.39
1.1
1.2
7.60
143.29
iu/ml
—
5
47
5
36
1.40
0.38
2.0
1.3
—
—
—
0
0
5
37
1.36
0.37
1.2
1.4
—
—
—
0
0
5
37
1.36
0.37
1.0
1.2
—
—
—
0
0
13
168
0.76
0.37
1.8
1.4
—
—
—
0
0
28
237
1.20
0.35
1.7
1.5
—
—
—
0
0
62
561
1.14
0.35
1.5
1.4
—
—
—
0
0
54
485
1.14
0.34
3.4
3.0
510.98
542.99
mosm/kgh2o
0.62
47
418
6
87
0.68
0.33
4.2
3.9
—
—
—
0
0
30
258
1.18
0.32
2.2
2.5
9.38
10.57
umol/l
0.12
24
228
6
47
1.28
0.32
1.3
1.1
—
—
—
0
0
56
615
0.89
0.31
5.5
4.3
0.00
0.00
estimate
-0.00
30
207
53
481
1.13
0.29
2.1
1.7
1116.07
1218.85
nmol/l
0.40
32
354
30
261
1.17
0.29
1.4
1.3
742.22
505.16
titre
—
9
62
12
94
1.29
0.28
2.1
2.9
—
—
—
0
0
33
291
1.15
0.27
2.8
2.6
1.61
1.79
%
0.76
27
263
8
65
1.24
0.27
10.0
2.2
2.35
1.63
mg/l
—
8
55
9
72
1.26
0.26
5.4
3.1
—
—
—
0
0
15
124
1.22
0.24
1.2
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
18.6
—
2146.00
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
10.1
—
1211.60
—
0
10
0
10
0.00
0.21
0.0
16.5
—
—
—
0
0
11
89
1.25
0.21
1.5
1.8
2.14
4.49
ug/l
0.31
11
81
18
208
0.86
0.21
2.4
3.4
6.41
5.77
kpa
1.10
18
202
11
133
0.82
0.20
1.5
1.4
—
—
—
0
0
20
175
1.15
0.19
1.8
1.4
—
—
—
0
0
14
119
1.19
0.18
1.7
1.5
—
—
—
0
0
78
742
1.07
0.17
2.8
2.3
57.94
63.74
u/l
0.34
67
681
25
277
0.89
0.17
3.2
4.5
3.01
32.43
ug/l
1.03
17
234
18
158
1.15
0.16
4.5
3.7
0.86
0.56
%
—
7
53
21
234
0.89
0.15
1.2
2.0
44.12
140.29
ug/g
2.91
15
178
18
159
1.14
0.15
4.9
3.9
0.14
0.19
%
—
7
48
11
93
1.19
0.14
2.3
2.0
—
—
—
0
0
13
149
0.87
0.14
1.2
1.1
—
—
—
0
0
14
159
0.87
0.13
2.4
3.7
—
—
—
0
0
10
117
0.85
0.13
1.0
1.2
38.74
169.17
u/ml
—
10
105
49
517
0.94
0.12
4.9
3.9
—
—
—
0
0
52
494
1.07
0.12
2.0
1.8
415.51
447.98
pmol/l
0.33
34
402
87
899
0.95
0.11
4.3
3.8
6.80
5.84
ph
—
5
60
15
134
1.13
0.11
1.3
1.3
—
—
—
0
0
10
86
1.17
0.11
1.5
1.6
—
—
—
0
0
73
704
1.05
0.10
3.3
3.1
—
—
—
0
0
29
271
1.08
0.10
1.9
1.7
—
—
—
0
0
5
45
1.11
0.10
2.2
3.1
28.20
37.84
umol/l
—
5
38
5
47
1.07
0.09
1.8
1.2
—
—
—
0
0
15
165
0.90
0.09
2.1
2.7
—
—
—
0
0
176
1783
0.96
0.08
22.6
20.2
331.77
331.53
g/l
0.13
176
1774
6
71
0.84
0.07
4.0
4.9
—
—
—
0
0
8
75
1.07
0.07
1.0
1.1
—
—
—
0
0
111
1131
0.97
0.07
4.3
4.0
0.00
0.00
estimate
-0.00
32
203
18
168
1.08
0.06
4.8
3.8
0.14
0.18
%
—
7
57
20
190
1.06
0.04
8.8
6.6
—
—
—
0
0
92
930
0.98
0.02
3.0
4.1
27.70
43.39
ng/l
1.03
68
674
111
1119
0.99
0.01
5.8
5.3
0.00
0.00
estimate
-0.00
30
214
28
273
1.03
0.01
7.4
5.7
2.14
1.09
mmol/l
0.53
21
221
40
406
0.98
0.00
1.3
1.4
3.06
2.63
g/l
0.29
20
240
13
128
1.02
0.00
1.8
1.3
—
—
—
0
0
18
182
0.99
0.00
4.9
3.7
2.07
0.92
%
—
7
71
62
622
1.00
0.00
3.5
3.6
—
—
—
0
0
17
171
0.99
0.00
1.4
2.1
—
—
—
0
0
112
1119
1.00
0.00
4.3
4.0
0.00
0.00
estimate
-0.00
33
229
65
648
1.00
0.00
4.9
4.1
—
—
—
0
0
11
113
0.97
0.00
13.0
6.7
—
—
—
0
0
18
183
0.98
0.00
4.9
3.6
—
—
—
0
0
5
55
0.91
0.00
1.0
1.2
—
—
—
0
0
5
49
1.02
0.00
1.8
3.6
18.40
31.26
u/ml
—
5
49
0
5
0.00
-0.00
0.0
1.0
—
18.60
—
0
5
0
6
0.00
-0.00
0.0
5.2
—
26.02
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
157.82
—
0
9
7
74
0.94
-0.00
2.1
1.8
—
—
—
0
0
9
96
0.94
-0.00
1.2
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
48.80
—
0
5
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
68
0.88
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.0
—
—
—
0
0
6
62
0.97
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
79
0.88
-0.00
1.3
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.20
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
99.04
—
0
9
0
5
0.00
-0.00
0.0
1.4
—
36.60
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
65.86
—
0
7

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_MELANOMA_UPPERLIMB – Melanoma in situ of upper limb, including shoulder

GWS hits: 1

This endpoint is excluded from FinRegistry analyses (omitted endpoint).