This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Melanoma in situ of upper limb, including shoulder
CD2_INSITU_MELANOMA_UPPERLIMB
melanoma: A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
223 |
4. Check minimum number of eventsNone |
223 |
5. Include endpointsNone |
223 |
6. Filter based on genotype QC (FinnGen only) |
223 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D03
- Name in latin
- Melanoma in situ regionis deltoideae
Similar endpoints
↥List of similar endpoints to
Melanoma in situ of upper limb, including shoulder
based on the number of shared cases.
Similar with more cases:
- Melanoma in situ of upper limb, including shoulder
- Melanoma in situ
- Melanoma in situ
- Malignant melanoma
- Malignant melanoma, excluding all cancers (controls excluding all cancers)
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 223 | 131 | 92 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | 68.34 | 66.98 | 70.27 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 191
- Matched controls
- 1908
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
+∞
273.1
190
*
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
184.8
133.0
129
21
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
595.2
48.6
46
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
14.1
36.9
67
70
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
46.9
34.1
41
11
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
27.1
33.3
46
22
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
9.9
32.7
73
112
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
17.0
31.2
51
40
L57.0
ICD-10 Finland
Actinic keratosis
6.9
24.2
69
145
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
7.4
20.6
53
94
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
9.0
20.3
45
63
C43.62
ICD-10 Finland
Malignant melanoma of upper extremity including shoulder: 'superficial spreading' type
86.9
14.8
16
*
TQW99
NOMESCO Finland
Other minor procedure on skin
6.9
14.4
37
64
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
12.9
14.3
25
22
R23.8
ICD-10 Finland
Other and unspecified skin changes
4.3
14.0
59
180
ZZR00
NOMESCO Finland
Flap of skin
11.8
13.7
25
24
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
5.9
13.3
39
80
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
20.9
13.2
19
10
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
+∞
12.6
12
*
S18
ICPC
Laceration/cut
3.0
11.8
113
626
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
11.1
11.3
21
21
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
26.9
11.3
15
6
SPAT1153
SPAT
Removal of sutures
2.9
11.0
89
436
S82
ICPC
Naevus/mole
3.9
10.7
47
146
C43.6
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of upper limb, including shoulder
116.0
10.5
11
*
8720/3-C44.6
ICD-O-3
Malignant melanoma, NOS, of skin of upper limb and shoulder
34.6
10.5
13
*
D03.5
ICD-10 Finland
Melanoma in situ of trunk
34.6
10.5
13
*
L82
ICD-10 Finland
Seborrhoeic keratosis
3.5
10.1
51
178
C43.60
ICD-10 Finland
Malignant melanoma of the upper extremity including the shoulder without histology
58.0
9.7
11
*
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
9.7
8.7
17
19
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
17.3
8.7
13
8
C43.69
ICD-10 Finland
Malignant melanoma of the upper extremity including shoulder other or unspecified histology
93.9
8.5
9
*
C43
ICD-10 Finland
Malignant melanoma of skin
93.9
8.5
9
*
D06BB10
ATC
imiquimod; topical
5.9
8.5
23
43
S77
ICPC
Malignant neoplasm of skin
11.5
8.5
15
14
8720/2-C44.6
ICD-O-3
Melanoma in situ of skin of upper limb and shoulder
+∞
8.4
8
*
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
23.2
8.1
11
5
ZXC50
NOMESCO Finland
Cryotherapy
6.3
7.4
19
33
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
31.3
7.2
9
*
8743/3-C44.9
ICD-O-3
Low cumulative sun damage melanoma of skin, NOS
41.5
6.8
8
*
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
6.9
6.8
16
25
XQ845
NOMESCO Finland
Dermatoscopy
15.0
6.5
10
7
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
72.1
6.5
7
*
QAE20
NOMESCO Finland
Excision and repair of scar or web of skin of head or neck
+∞
6.3
6
*
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
9.0
6.1
12
14
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
135
976
1.97
5.64
6.1
6.1
1.2
1.2
mmol/l
0.64
112
816
125
903
1.87
5.00
6.1
5.4
1.2
1.2
mmol/l
0.69
111
819
110
767
1.86
4.89
2.7
2.3
85.4
78.2
nmol/l
1.82
88
670
97
653
1.86
4.80
4.0
3.5
2.3
2.4
mmol/l
0.56
74
573
33
148
2.44
4.79
2.6
3.4
84.2
81.2
ng/l
0.10
21
129
198
1738
2.24
3.67
18.0
14.7
77.0
77.0
ml/min/173m2
0.01
177
1415
10
27
3.83
3.39
1.1
1.3
—
—
—
0
0
72
484
1.72
3.36
1.6
1.6
24.0
21.9
nmol/l
0.37
55
395
166
1390
1.76
3.34
4.7
4.1
11.4
13.0
mm/h
0.72
147
1264
184
1594
1.88
3.23
19.0
16.3
39.3
39.5
%
0.09
125
1081
41
240
1.87
3.01
5.4
4.8
34.2
32.8
%
0.29
19
153
202
1818
2.18
3.00
5.5
5.2
2.7
2.7
mmol/l
0.30
170
1635
13
46
2.94
2.97
2.2
1.2
—
—
—
0
0
198
1775
2.03
2.88
4.9
4.6
4.7
4.6
mmol/l
0.56
166
1611
197
1764
2.00
2.86
5.1
4.6
1.5
1.5
mmol/l
0.34
162
1592
104
796
1.57
2.80
2.2
2.0
90.3
95.6
pmol/l
0.43
46
381
198
1789
1.95
2.60
5.2
4.8
5.8
6.0
mmol/l
1.25
161
1614
192
1721
1.83
2.54
6.4
6.0
38.8
40.4
mmol/mol
2.43
162
1584
51
337
1.67
2.47
3.7
3.1
0.8
0.8
ug/l
0.15
33
228
188
1679
1.76
2.47
6.5
4.7
1.8
2.0
mu/l
0.89
164
1491
47
305
1.69
2.43
4.8
3.2
0.8
0.8
mmol/l
1.09
40
285
209
1934
2.28
2.42
12.5
10.5
24.9
24.4
u/l
0.19
197
1847
110
880
1.49
2.28
4.2
4.0
—
—
—
0
0
189
1704
1.72
2.22
4.7
4.1
1.3
1.3
mmol/l
0.28
152
1529
207
1925
2.05
2.08
19.3
18.1
80.9
78.6
umol/l
0.42
207
1925
127
1060
1.46
2.05
8.4
9.6
4.0
4.1
e9/l
0.23
102
932
198
1821
1.78
1.99
16.6
15.3
20.3
23.6
mg/l
0.61
167
1465
5
11
4.62
1.95
2.0
1.2
—
—
—
0
0
9
36
2.56
1.76
1.2
1.4
—
—
—
0
0
165
1471
1.47
1.73
8.6
7.3
74.2
79.1
u/l
1.27
150
1366
45
315
1.54
1.71
2.9
2.9
3.0
2.7
e6/l
0.09
24
169
102
837
1.40
1.71
5.0
4.2
35.2
35.1
g/l
0.03
90
784
156
1378
1.44
1.70
5.4
3.9
15.1
14.9
pmol/l
0.44
130
1218
5
14
3.63
1.62
1.6
1.0
—
—
—
0
0
35
236
1.57
1.57
4.4
8.1
—
—
—
0
0
204
1916
1.76
1.57
20.1
17.8
4.0
4.0
mmol/l
0.39
199
1856
11
51
2.22
1.53
2.1
1.5
—
—
—
0
0
118
1007
1.36
1.50
2.9
2.7
—
—
—
0
0
5
16
3.17
1.44
1.2
1.1
—
—
—
0
0
5
16
3.17
1.44
1.0
1.5
19.6
15.1
u/l
—
5
16
5
16
3.17
1.44
1.4
1.2
—
—
—
0
0
45
328
1.47
1.42
2.8
2.7
0.8
1.1
e6/l
0.32
24
177
9
40
2.30
1.42
1.7
1.3
—
—
—
0
0
74
594
1.37
1.36
2.7
2.0
297.5
208.1
u/l
0.38
66
553
9
43
2.14
1.32
1.7
1.5
—
—
—
0
0
63
495
1.38
1.31
3.4
2.8
6255.3
6574.9
umol/l
0.02
57
413
41
298
1.46
1.31
1.4
1.3
23.5
30.8
iu/ml
0.31
11
100
56
432
1.40
1.30
3.4
2.3
—
—
—
0
0
69
556
1.35
1.22
3.9
3.1
1.2
0.6
e6/l
0.30
52
418
14
79
1.82
1.20
2.3
2.4
39.4
40.9
u/l
0.11
14
70
8
38
2.15
1.19
2.0
1.5
—
—
—
0
0
5
20
2.53
1.15
1.8
1.7
—
—
—
0
0
130
1154
1.30
1.14
4.0
3.0
50.9
48.8
u/l
0.11
117
1075
50
387
1.38
1.14
3.3
2.8
2.5
2.5
mmol/l
0.51
43
343
16
97
1.70
1.10
1.4
2.1
1.1
1.5
g/l
0.88
11
83
12
67
1.84
1.07
1.9
2.1
—
—
—
0
0
9
46
2.00
1.05
1.4
1.3
—
—
—
0
0
18
115
1.61
1.03
1.7
1.8
—
—
—
0
0
57
458
1.33
1.02
4.8
4.9
20.3
20.9
%
0.15
28
229
61
497
1.31
0.99
1.5
1.6
1.3
1.3
mmol/l
0.02
46
412
83
706
1.28
0.98
4.4
3.2
—
—
—
0
0
52
415
1.33
0.98
3.0
1.7
0.9
1.4
mg/l
0.94
40
330
6
116
0.50
0.97
1.3
1.3
—
—
—
0
0
11
62
1.81
0.96
1.9
1.9
—
—
—
0
0
7
37
1.92
0.95
1.3
1.4
—
—
—
0
0
7
37
1.92
0.95
1.3
1.4
—
—
—
0
0
40
308
1.36
0.95
2.0
1.9
—
—
—
0
0
9
52
1.76
0.93
1.9
1.5
—
—
—
0
0
11
63
1.78
0.92
2.1
2.7
—
—
—
0
0
6
32
1.90
0.82
2.3
1.4
—
—
—
0
0
32
246
1.35
0.78
1.8
1.4
—
—
—
0
0
9
53
1.73
0.76
1.0
1.4
—
—
—
0
0
5
24
2.11
0.75
1.0
1.1
—
—
—
0
0
5
24
2.11
0.75
2.4
1.3
—
—
—
0
0
7
41
1.73
0.70
1.0
1.1
—
—
—
0
0
43
520
0.79
0.70
5.4
4.3
0.0
0.0
estimate
0.00
24
181
20
147
1.40
0.64
13.6
6.7
14.3
10.0
mmol/l
0.83
20
139
68
592
1.21
0.63
5.9
5.4
11.4
2.7
ug/l
0.45
58
526
113
1033
1.19
0.62
6.8
6.1
10.0
11.2
umol/l
1.47
105
974
8
51
1.59
0.61
2.0
1.5
—
—
—
0
0
64
729
0.83
0.59
4.3
4.2
—
—
—
0
0
6
35
1.73
0.58
1.8
1.3
15175.0
29214.5
e6/l
—
6
22
34
278
1.26
0.55
1.5
1.3
16.9
9.3
u/ml
0.24
11
104
9
62
1.47
0.54
1.0
1.7
—
—
—
0
0
44
375
1.22
0.50
5.2
3.9
248.4
197.5
ng/l
0.15
38
312
15
110
1.39
0.50
3.4
3.2
1.6
2.0
mmol/l
—
8
84
84
764
1.16
0.46
3.3
2.6
185.4
126.9
ug/l
0.97
74
688
122
1143
1.15
0.44
4.2
4.4
6.5
6.7
mmol/l
0.31
117
1063
7
51
1.38
0.44
1.9
1.7
—
—
—
0
0
26
213
1.25
0.43
3.3
3.7
—
—
—
0
0
18
227
0.77
0.42
3.3
4.5
2.2
27.8
ug/l
0.78
11
190
36
307
1.21
0.42
3.9
1.9
32.1
29.7
s
1.26
36
298
13
170
0.75
0.40
7.2
5.7
1.4
1.4
mmol/l
0.01
13
162
6
41
1.48
0.36
1.0
1.1
3.9
3.9
mmol/l
—
6
36
6
42
1.44
0.36
1.5
1.2
—
—
—
0
0
13
100
1.32
0.34
1.7
1.7
—
—
—
0
0
25
211
1.21
0.33
2.0
2.6
9.3
9.8
umol/l
0.04
19
184
73
784
0.90
0.29
3.1
4.0
20.8
46.8
ng/l
2.87
54
568
53
484
1.12
0.27
2.6
2.0
2.9
3.3
mg/l
0.48
35
414
11
86
1.29
0.26
1.4
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
21
239
0.87
0.20
6.2
5.9
102.8
103.9
mmol/l
0.41
21
232
6
48
1.26
0.20
1.8
1.3
—
10.3
—
0
10
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
7
61
1.15
0.17
1.3
1.2
—
—
—
0
0
12
140
0.85
0.15
3.1
2.7
41.5
62.2
ml/min/173m2
—
6
56
91
945
0.94
0.15
4.0
4.0
0.0
0.0
estimate
0.00
26
179
13
112
1.17
0.14
1.7
1.8
—
—
—
0
0
13
113
1.16
0.13
2.0
1.8
—
—
—
0
0
24
219
1.11
0.13
1.9
1.9
—
—
—
0
0
12
105
1.15
0.11
7.8
7.8
26.4
24.6
mmol/l
0.58
12
98
91
937
0.95
0.11
4.1
4.0
0.0
0.0
estimate
0.00
24
190
91
936
0.95
0.10
5.5
5.4
0.0
0.0
estimate
0.00
24
186
5
44
1.14
0.10
1.2
1.3
—
—
—
0
0
16
175
0.91
0.09
2.3
3.4
6.5
5.8
kpa
1.16
16
170
15
137
1.10
0.07
1.4
1.6
—
—
—
0
0
7
83
0.84
0.07
1.0
1.0
—
—
—
0
0
24
253
0.94
0.06
1.6
1.4
—
—
—
0
0
58
594
0.97
0.04
3.2
3.0
29.0
32.7
u/l
0.81
53
560
24
229
1.05
0.04
4.9
6.1
2.6
1.1
mmol/l
0.69
18
184
39
380
1.03
0.03
1.3
1.2
0.9
1.0
u/ml
0.17
13
105
23
223
1.03
0.01
2.0
1.9
—
—
—
0
0
17
176
0.96
0.00
2.2
3.4
2.5
2.2
mmol/l
0.11
12
136
63
624
1.01
0.00
2.8
2.3
55.0
57.0
u/l
0.15
54
574
64
638
1.00
0.00
2.4
3.3
2108.7
1413.8
ng/l
0.45
54
533
41
405
1.02
0.00
1.9
1.8
428.5
457.7
pmol/l
0.25
26
332
40
402
0.99
0.00
2.1
1.7
1037.0
1245.0
nmol/l
0.80
24
294
0
5
0.00
0.00
0.0
1.2
—
106.4
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
0.00
1.8
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
3.2
—
83.8
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
6
64
0.94
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
54
0.92
0.00
2.6
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
10.1
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_MELANOMA_UPPERLIMB – Melanoma in situ of upper limb, including shoulder
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).