No definition available.
Congenital mitral valve regurgitation
Q17_CONGENITAL_MITRAL_VALVE_REGURGITATION
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
65 |
4. Check minimum number of eventsNone |
65 |
5. Include endpointsNone |
65 |
6. Filter based on genotype QC (FinnGen only) |
63 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Congenital mitral valve regurgitation
based on the number of shared cases.
Similar with more cases:
- Left ventricular outflow tract obstruction, narrow definition
- Congenital malformations of heart and great arteries
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 63 | 35 | 28 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 12.23 | 12.35 | 12.09 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 65
- Matched controls
- 650
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
+∞
73.5
56
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
18.2
31.2
34
37
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
17.0
31.0
43
67
B01AA03
ATC
warfarin; systemic
17.3
27.7
29
29
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
55.4
27.5
32
11
XF400
NOMESCO Finland
ECG with 12 standard connections
11.7
23.1
37
66
201
Kela drug reimbursment
Chronic cardiac insufficiency
60.1
22.9
26
7
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
43.3
22.9
28
11
XF404
NOMESCO Finland
Ambulatory ECG
29.6
20.7
28
16
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
64.9
19.7
22
5
ZXE20
NOMESCO Finland
More than three and less than five hours
11.4
19.4
26
36
C03CA01
ATC
furosemide; systemic
10.3
18.3
27
42
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
9.5
17.4
28
48
XF402
NOMESCO Finland
ECG with work load test
30.1
15.9
21
10
XF600
NOMESCO Finland
Bloodpressure measurement
9.6
15.6
23
35
C03DA01
ATC
spironolactone; oral
20.1
14.6
22
16
C01AA05
ATC
digoxin; systemic
32.1
13.3
17
7
I34.1
ICD-10 Finland
Mitral (valve) prolapse
38.2
12.3
15
5
WX872
NOMESCO Finland
Intensive care
38.2
12.3
15
5
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.1
11.9
42
149
WX408
NOMESCO Finland
General anesthesy, balanced
6.0
11.8
37
118
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
+∞
11.8
11
*
7466A
ICD-9 Finland
Other congenital anomalies of heart, Congenital mitral insufficiency
+∞
11.8
11
*
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
39.8
10.8
13
*
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
130.1
10.8
11
*
TPH07
NOMESCO Finland
Cathetrisation of artery
7.0
10.6
20
39
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
26.5
9.8
13
6
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
36.1
9.8
12
*
C09AA02
ATC
enalapril; systemic
9.1
9.3
20
30
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
5.2
8.9
25
70
ZXE30
NOMESCO Finland
More than five and less than seven hours
12.1
8.9
16
17
B01AB05
ATC
enoxaparin; parenteral
5.3
8.9
24
65
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
24.0
8.8
12
6
FM2CE, ,
NOMESCO Finland
10.5
8.8
17
21
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
+∞
8.5
8
*
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
38.7
8.3
10
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.5
8.1
18
28
R4110
NOMESCO Finland
Physiotherapy
4.4
7.9
32
118
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
29.0
7.8
10
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
8.5
7.8
17
26
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
+∞
7.4
7
*
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
+∞
7.4
7
*
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
23.2
7.4
10
5
XF622
NOMESCO Finland
Measurement of minute volume of heart
44.8
6.9
8
*
WX892
NOMESCO Finland
Monitored bed care
7.5
6.9
16
27
I48
ICD-10 Finland
Atrial fibrillation and flutter
9.1
6.9
14
19
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
11.0
6.6
12
13
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
77.1
6.6
7
*
XF640, ,
NOMESCO Finland
77.1
6.6
7
*
61
HP
Catheterization and pressure measurement of the left side of the heart
77.1
6.6
7
*
Z01.8
ICD-10 Finland
Other specified special examinations
4.1
6.4
23
76
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
6.7
6.4
16
30
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
+∞
6.3
6
*
I37.0
ICD-10 Finland
Pulmonary valve stenosis
+∞
6.3
6
*
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
+∞
6.3
6
*
C07AB07
ATC
bisoprolol; oral
3.9
6.3
25
89
207
Kela drug reimbursment
Chronic arrhythmias
9.5
6.2
12
15
Z2221
NOMESCO Finland
Medical doctor
3.6
6.1
31
130
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
17.1
6.1
9
6
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
42
137
6.84
13.45
33.4
9.8
1.74
1.24
inr
—
9
45
29
68
6.89
13.12
11.2
4.9
34.32
28.75
s
1.95
29
68
28
67
6.58
12.31
8.7
3.7
2200.14
428.05
ng/l
1.08
22
43
20
36
7.58
11.52
16.1
6.7
92.20
93.33
%
0.08
20
36
13
11
14.40
7.99
4.2
4.7
87.69
89.91
%
0.07
13
11
17
30
7.28
7.07
3.1
6.5
157.71
194.30
%
0.74
17
30
28
105
3.93
6.59
4.6
2.9
—
—
—
0
0
19
56
4.38
6.15
2.4
1.7
—
—
—
0
0
16
41
4.85
6.14
2.3
1.5
—
—
—
0
0
16
44
4.50
5.61
2.1
1.4
—
—
—
0
0
8
7
12.79
4.93
2.5
1.1
—
—
—
0
0
8
7
12.79
4.93
2.5
1.3
—
—
—
0
0
26
111
3.24
4.79
6.0
2.5
32.62
46.34
ng/l
0.19
20
51
7
5
15.43
4.68
2.4
1.2
—
—
—
0
0
7
5
15.43
4.68
2.4
1.2
—
—
—
0
0
38
213
2.89
4.20
4.9
3.1
—
—
—
0
0
23
98
3.08
4.18
6.5
3.4
1.36
1.91
mg/l
0.22
17
64
7
7
11.01
4.11
3.0
3.9
578.00
162.39
ug/l
—
7
7
6
5
13.01
3.84
1.3
1.0
—
—
—
0
0
11
25
5.07
3.83
1.6
2.7
9.78
4.89
ug/l
0.79
11
19
39
232
2.70
3.70
16.1
12.7
1.21
1.22
mmol/l
1.77
39
211
6
6
10.84
3.57
1.8
1.2
—
—
—
0
0
7
10
7.68
3.46
1.9
1.4
—
—
—
0
0
19
83
2.82
3.22
21.4
9.3
2.20
1.31
mmol/l
0.92
14
55
36
217
2.48
3.17
18.5
13.3
1.21
1.23
mmol/l
1.90
36
208
5
5
10.67
3.03
2.8
1.2
—
—
—
0
0
10
29
3.88
2.83
1.4
2.2
—
—
—
0
0
19
89
2.60
2.79
13.5
14.8
24.59
24.73
mmol/l
0.08
19
89
7
15
5.09
2.67
2.3
1.8
—
—
—
0
0
38
254
2.19
2.43
3.8
3.2
87.14
70.31
ug/l
0.35
38
239
9
30
3.31
2.25
2.0
2.4
—
—
—
0
0
17
84
2.39
2.20
7.2
9.0
23.29
23.48
mmol/l
0.12
17
84
5
11
4.82
1.98
3.2
4.9
—
—
—
0
0
8
28
3.11
1.93
3.5
2.0
—
—
—
0
0
43
319
2.03
1.90
5.9
4.2
56.40
33.92
u/l
1.22
43
305
7
23
3.28
1.86
7.4
16.8
1.29
1.67
%
—
7
23
12
55
2.45
1.80
7.3
12.5
105.25
104.93
mmol/l
0.11
12
55
5
14
3.77
1.64
1.0
1.1
—
—
—
0
0
6
20
3.20
1.62
12.0
12.4
24.33
24.30
mmol/l
—
6
20
42
505
0.52
1.58
4.2
4.0
—
—
—
0
0
7
27
2.78
1.56
1.1
1.4
—
—
—
0
0
6
22
2.90
1.47
14.3
6.2
25.22
23.43
mmol/l
—
6
22
6
23
2.77
1.40
12.2
11.2
0.52
0.59
%
—
6
23
5
18
2.92
1.31
1.8
1.6
—
—
—
0
0
17
103
1.88
1.29
21.2
9.7
1.21
1.29
mmol/l
0.48
17
98
8
38
2.26
1.23
1.6
1.3
—
—
—
0
0
21
138
1.77
1.23
3.4
2.7
50.33
55.62
u/l
0.28
21
128
59
527
2.29
1.21
31.0
11.9
23.52
21.73
mg/l
0.20
46
379
25
178
1.66
1.09
4.2
4.1
—
—
—
0
0
43
353
1.64
1.05
20.7
8.2
97.78
98.97
ml/min/173m2
0.12
34
256
19
127
1.70
1.04
1.6
1.6
87.81
95.64
pmol/l
0.47
14
66
9
49
1.97
1.04
6.8
7.6
57.11
52.02
ng/l
—
9
49
6
27
2.34
0.96
3.7
5.0
6.02
17.19
umol/l
—
6
18
47
406
1.57
0.82
4.0
3.1
1.36
1.42
mmol/l
0.41
47
379
5
23
2.27
0.78
12.8
11.2
0.90
1.29
%
—
5
23
5
26
2.00
0.72
1.0
1.3
0.24
0.24
g/l
—
5
26
5
26
2.00
0.72
1.2
1.3
—
—
—
0
0
5
27
1.92
0.70
1.2
1.3
0.90
1.31
g/l
—
5
27
0
23
0.00
0.59
0.0
1.7
—
0.00
—
0
5
11
74
1.59
0.58
1.3
1.6
1.46
1.34
%
0.36
11
69
12
83
1.55
0.56
3.3
2.2
—
—
—
0
0
56
523
1.51
0.49
38.7
14.7
13.41
13.73
%
0.76
56
516
41
364
1.34
0.48
5.0
4.6
9.22
8.81
mm/h
0.09
41
340
18
219
0.75
0.40
1.7
1.7
0.82
2.59
u/ml
—
5
43
21
174
1.31
0.38
3.5
3.2
—
—
—
0
0
16
128
1.33
0.36
2.8
3.5
0.00
0.00
estimate
—
6
48
8
61
1.35
0.30
3.9
2.1
21.00
26.92
u/l
—
8
50
28
253
1.19
0.22
3.7
3.2
0.00
0.00
estimate
—
6
49
0
11
0.00
0.21
0.0
1.0
—
60.52
—
0
6
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
8.07
—
0
12
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
7.04
—
0
13
0
14
0.00
0.20
0.0
1.1
—
2.06
—
0
8
0
14
0.00
0.20
0.0
1.0
—
8.20
—
0
7
0
14
0.00
0.20
0.0
1.0
—
17.93
—
0
14
14
158
0.85
0.14
2.2
2.6
—
—
—
0
0
27
251
1.13
0.13
5.6
4.5
0.00
0.00
estimate
—
6
49
5
44
1.15
0.10
1.6
1.7
—
—
—
0
0
5
61
0.80
0.08
4.8
3.9
2.49
1.57
ug/l
—
5
55
7
67
1.05
0.08
4.1
2.1
—
—
—
0
0
6
73
0.80
0.08
1.2
1.5
—
—
—
0
0
27
257
1.09
0.07
3.7
3.2
0.00
0.00
estimate
—
6
45
13
141
0.90
0.06
2.0
2.5
—
—
—
0
0
22
227
0.95
0.01
3.4
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
23.47
—
0
7
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.37
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
110.14
—
0
7
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
9
93
0.96
-0.00
1.3
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_CONGENITAL_MITRAL_VALVE_REGURGITATION – Congenital mitral valve regurgitation
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).