No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
298 |
4. Check minimum number of eventsNone |
298 |
5. Include endpointsNone |
298 |
6. Filter based on genotype QC (FinnGen only) |
287 |
Control definitions (FinnGen only)
- Control exclude
- M13_ARTHROPATHIES
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M20
- Name in latin
- Alia deformitas hallucis [acquisita]
Similar endpoints
↥List of similar endpoints to
Other deformity of hallux (acquired)
based on the number of shared cases.
Similar with more cases:
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1768 | 1316 | 446 |
| Only index persons | 1661 | 1261 | 400 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.04 | 0.01 |
| Only index persons | 0.04 | 0.05 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 56.00 | 56.11 | 55.53 |
| Only index persons | 55.69 | 55.82 | 55.28 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 287 | 220 | 67 |
| Unadjusted period prevalence (%) | 0.07 | 0.08 | 0.03 |
| Median age at first event (years) | 55.20 | 53.99 | 59.15 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 298
- Matched controls
- 2980
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M20.3
ICD-10 Finland
Other deformity of hallux (acquired)
+∞
307.7
266
*
M20.1
ICD-10 Finland
Hallux valgus (acquired)
84.2
220.0
121
24
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
30.4
112.3
79
35
M17.1
ICD-10 Finland
Other primary gonarthrosis
23.0
105.4
84
50
M19.0
ICD-10 Finland
Primary arthrosis of other joints
39.0
105.0
67
22
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
+∞
102.1
92
*
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
197.1
85.2
85
6
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
16.9
64.8
58
42
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
22.7
62.8
48
25
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
+∞
62.8
58
*
WX320
NOMESCO Finland
Spinalanesthesy
7.4
61.2
122
255
M16.1
ICD-10 Finland
Other primary coxarthrosis
21.9
58.2
45
24
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
47.1
44
*
9271
FHL
Hallux surgery
+∞
43.8
41
*
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
79.3
42.5
47
7
M20.2
ICD-10 Finland
Hallux rigidus
128.5
42.0
44
*
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
+∞
40.5
38
*
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
+∞
40.5
38
*
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
+∞
40.5
38
*
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
416.7
37.9
37
*
7351A
ICD-9 Finland
Acquired deformities of toe, Hallux varus (acquired)
+∞
34.0
32
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
9.8
34.0
42
49
M25.5
ICD-10 Finland
Pain in joint
4.5
33.6
116
369
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
78.9
31.6
35
5
M20.5
ICD-10 Finland
Other deformities of toe(s) (acquired)
+∞
30.8
29
*
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
+∞
29.7
28
*
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
12.2
28.9
30
27
NHG82
NOMESCO Finland
Fusion of other tarsal joint
+∞
27.5
26
*
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
106.7
27.2
29
*
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
271.9
25.1
25
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.5
24.7
158
734
73799
ICD-8 Finland
Hallux valgus and varus
+∞
24.3
23
*
7350A
ICD-9 Finland
Acquired deformities of toe, Hallux valgus (acquired)
+∞
24.3
23
*
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
6.3
24.0
44
80
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
248.3
23.0
23
*
L15
ICPC
Knee symptom/complaint
3.7
21.6
85
287
L17
ICPC
Foot/toe symptom/complaint
3.3
21.3
117
487
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
29.5
20.4
27
10
N02AX02
ATC
tramadol; systemic, rectal
3.1
20.0
146
711
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.6
19.9
53
134
M01AX05
ATC
glucosamine; oral
3.8
19.5
71
226
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
6.8
19.3
32
52
ZXA00
NOMESCO Finland
Right side
3.2
19.0
105
434
S18
ICPC
Laceration/cut
2.9
17.9
162
873
L04AX03
ATC
methotrexate; systemic
7.1
17.8
28
43
B01AB05
ATC
enoxaparin; parenteral
2.9
16.8
109
489
NH3EA
NOMESCO Finland
Feet X-ray examination with load
95.5
16.7
18
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
14.7
16.3
27
20
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
15.7
16.2
26
18
M77.4
ICD-10 Finland
Metatarsalgia
5.5
16.1
33
66
M01AH05
ATC
etoricoxib; oral
2.8
16.0
190
1155
N03AX12
ATC
[U] gabapentin; oral
3.5
15.9
63
210
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
20.7
15.8
23
12
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
+∞
15.8
15
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
19.0
15.4
23
13
N02AJ06
ATC
codeine and paracetamol; systemic
2.7
15.3
137
719
M09AX01
ATC
hyaluronic acid; parenteral
16.2
15.2
24
16
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
33.7
15.0
19
6
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
5.2
14.9
32
67
M79.6
ICD-10 Finland
Pain in limb
2.6
14.8
145
792
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
+∞
14.7
14
*
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
38.1
14.6
18
5
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
157.4
14.6
15
*
1221
FHL
Arthroscopy and meniscus surgery
157.4
14.6
15
*
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
28.8
14.5
19
7
M19.9
ICD-10 Finland
Arthrosis, unspecified
12.3
14.1
25
22
M13.9
ICD-10 Finland
Arthritis, unspecified
12.9
13.9
24
20
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
4.5
13.7
36
89
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
78.9
13.7
15
*
M01AH01
ATC
celecoxib; oral
3.2
13.5
64
237
L16
ICPC
Ankle symptom/complaint
3.6
12.8
47
148
NFB40
NOMESCO Finland
Primary total prosthetic replacement of hip joint using hybrid technique
25.6
12.6
17
7
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
+∞
12.6
12
*
P01BA02
ATC
hydroxychloroquine; oral
9.6
12.5
25
28
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.6
12.5
100
489
N03AX16
ATC
[U] pregabalin
2.7
12.4
80
351
SPAT1153
SPAT
Removal of sutures
2.5
12.3
106
536
NF1AA
NOMESCO Finland
Hip X-ray examination
4.4
11.9
31
76
WX002
NOMESCO Finland
Sedation and analgesia
2.8
11.8
69
286
WX214
NOMESCO Finland
Plexus blockade at the ankle
+∞
11.5
11
*
ZXA05
NOMESCO Finland
Left side
2.6
11.4
85
399
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
3.7
11.3
38
113
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
5.2
10.9
23
47
Z01.2
ICD-10 Finland
Dental examination
2.3
10.9
144
868
M54.4
ICD-10 Finland
Lumbago with sciatica
2.8
10.7
62
256
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.9
10.5
56
220
J01DB01
ATC
cefalexin; oral
2.9
10.5
253
1962
M22.4
ICD-10 Finland
Chondromalacia patellae
+∞
10.5
10
*
A02BC05
ATC
esomeprazole; systemic
2.2
10.4
136
813
J01FF01
ATC
clindamycin; systemic
2.4
10.3
91
460
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.7
10.2
34
100
M67.0
ICD-10 Finland
Short Achilles tendon (acquired)
41.6
10.0
12
*
B01AF01
ATC
rivaroxaban; oral
3.3
10.0
40
133
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
27.1
9.9
13
5
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.0
9.7
29
79
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
9.6
122
714
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.5
9.6
24
57
M01AH02
ATC
rofecoxib; oral
3.1
9.5
42
148
M48.0
ICD-10 Finland
Spinal stenosis
3.1
9.5
43
154
WX111
NOMESCO Finland
Local infiltration anesthesia
103.2
9.5
10
*
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
+∞
9.4
9
*
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
+∞
9.4
9
*
M02AA07
ATC
piroxicam; topical
2.2
9.3
117
682
R4110, ,
SPAT
3.3
9.2
37
123
WZA00
NOMESCO Finland
Concise certificate
4.8
9.2
21
46
M01AX17
ATC
nimesulide; oral
2.4
9.1
77
379
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
37.9
9.1
11
*
L01BA01
ATC
methotrexate; systemic
37.9
9.1
11
*
N02BE01
ATC
paracetamol; systemic, rectal
3.3
8.8
270
2228
J02AC01
ATC
fluconazole; systemic
2.1
8.8
139
879
SPAT1229
SPAT
Assessment of need for aid
3.6
8.7
30
90
L03.0
ICD-10 Finland
Cellulitis of finger and toe
3.7
8.7
29
85
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.3
8.4
75
377
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
+∞
8.4
8
*
L84
ICD-10 Finland
Corns and callosities
6.8
8.3
20
31
H02AB07
ATC
prednisone; oral
2.7
8.3
48
197
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
12.2
8.2
14
12
NHQ40
NOMESCO Finland
Amputation of toe
17.8
8.1
12
7
UJF32
NOMESCO Finland
Coloscopy
2.2
8.1
89
487
M03BX02
ATC
tizanidine; oral
2.0
8.0
186
1337
L13
ICPC
Hip symptom/complaint
2.5
7.9
58
267
M01AC06
ATC
meloxicam; systemic, rectal
2.1
7.9
109
651
N06AX21
ATC
duloxetine; oral
2.8
7.8
41
159
L89
ICPC
Osteoarthrosis of hip
15.6
7.8
12
8
WX702
NOMESCO Finland
Supraglottic ventilation device
3.8
7.7
24
67
NG2AA
NOMESCO Finland
Patella X-ray examination
25.8
7.6
10
*
H02AB06
ATC
prednisolone; systemic
2.0
7.5
138
907
9273
FHL
Other surgery for toe deformity or pain condition, e.g., Morton, hammer toe
82.1
7.5
8
*
H13
ICPC
Plugged feeling ear
2.3
7.4
66
330
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
9.7
7.4
14
15
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
+∞
7.3
7
*
M54.5
ICD-10 Finland
Low back pain
2.0
7.3
101
600
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
7.3
141
941
M01AE01
ATC
ibuprofen; systemic, rectal
3.0
7.2
271
2302
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.6
7.1
45
193
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
5.7
7.0
19
35
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
3.9
7.0
21
57
J01DA01
ATC
[U] cefalexin
1.9
7.0
186
1372
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.6
7.0
23
67
A02BC02
ATC
pantoprazole; systemic
2.0
7.0
202
1534
SFA10
NOMESCO Finland
One-surface restoration
1.9
7.0
160
1125
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
4.3
6.9
18
44
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
6.9
65
332
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.8
6.9
21
58
SPAT1211
SPAT
Application of soft bandage
3.1
6.9
30
105
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
41.0
6.8
8
*
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
41.0
6.8
8
*
NHM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of ankle or foot
41.0
6.8
8
*
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.4
6.7
25
79
M19.8
ICD-10 Finland
Other specified arthrosis
6.7
6.7
16
25
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
23.1
6.7
9
*
L03
ICPC
Low back symptom/complaint
2.1
6.6
82
465
S20
ICPC
Corn/callosity
10.4
6.6
12
12
R29
ICPC
Respiratory symptom/complaint other
3.6
6.6
22
65
A46
ICD-10 Finland
Erysipelas
2.5
6.5
42
181
M19.2
ICD-10 Finland
Other secondary arthrosis
71.3
6.4
7
*
M10.0
ICD-10 Finland
Idiopathic gout
11.4
6.3
11
10
E0000UV, ,
ATC
1.9
6.3
129
865
R06AE07
ATC
cetirizine; oral
1.9
6.3
133
901
AA1AD
NOMESCO Finland
CT of head and brain
2.0
6.3
87
513
J01DA09
ATC
[U] cefadroxil
2.0
6.3
81
466
M96.0
ICD-10 Finland
Pseudarthrosis after fusion or arthrodesis
+∞
6.3
6
*
9351
FHL
Metatarsus osteotomies
+∞
6.3
6
*
L04AA13
ATC
[U] leflunomide
+∞
6.3
6
*
72410
ICD-8 Finland
Internal derangement of joint, Other shoulder derangement
+∞
6.3
6
*
M17.5
ICD-10 Finland
Other secondary gonarthrosis
+∞
6.3
6
*
B01AX06
ATC
[U] rivaroxaban
+∞
6.3
6
*
NHL99
NOMESCO Finland
Other operation on muscle or tendon of ankle or foot
27.3
6.3
8
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
27.3
6.3
8
*
M35.7
ICD-10 Finland
Hypermobility syndrome
27.3
6.3
8
*
M01AB05
ATC
diclofenac; systemic, rectal
1.9
6.2
187
1412
ZXA10
NOMESCO Finland
Bilateral
2.1
6.2
63
331
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.6
6.2
38
160
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.1
6.2
68
369
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.5
6.1
42
187
K02.1
ICD-10 Finland
Caries of dentine
1.8
6.0
163
1188
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
151
962
2.15
9.60
2.6
2.5
—
—
—
0
0
16
13
12.93
9.47
1.7
1.0
—
—
—
0
0
225
1705
2.30
8.85
5.9
3.3
11.28
12.27
mm/h
0.65
210
1542
158
1048
2.08
8.79
14.5
12.1
1.32
1.21
inr
0.66
46
319
65
309
2.41
8.25
1.4
1.2
28.47
14.84
iu/ml
0.45
26
91
277
2377
3.35
7.30
15.9
13.0
20.32
24.68
mg/l
1.57
228
1772
148
1020
1.90
6.80
2.3
2.2
82.33
78.86
nmol/l
0.74
128
900
183
1355
1.91
6.69
3.3
4.5
6.38
6.74
mmol/l
2.28
171
1263
91
540
1.99
6.48
2.4
2.0
2.74
3.04
mg/l
0.77
83
444
105
666
1.89
6.08
2.7
3.2
864.41
1211.77
ng/l
1.19
86
564
144
1015
1.81
5.90
3.0
4.8
35.58
35.58
g/l
0.00
123
938
85
507
1.95
5.90
1.9
2.3
6429.87
13920.04
umol/l
0.78
75
441
56
288
2.16
5.81
1.4
1.1
2.91
2.91
u/ml
0.00
21
113
178
1347
1.80
5.66
7.7
8.7
3.94
4.07
e9/l
0.39
159
1168
149
1082
1.75
5.35
4.0
5.3
1.23
1.22
mmol/l
0.67
137
982
226
1857
1.90
5.29
7.6
7.4
73.70
78.74
u/l
1.70
210
1736
234
1955
1.92
5.07
4.8
4.0
14.96
14.93
pmol/l
0.04
209
1764
101
669
1.77
4.91
2.0
1.9
203.75
165.48
u/l
0.19
95
636
147
1084
1.70
4.85
6.9
4.7
27.93
27.77
%
0.06
137
1019
145
1066
1.70
4.83
6.4
4.6
56.81
57.15
%
0.14
135
1001
281
2534
2.91
4.75
17.4
15.3
139.65
139.73
mmol/l
0.22
275
2456
88
566
1.79
4.70
1.4
1.5
22.39
21.24
nmol/l
0.26
77
476
281
2539
2.87
4.63
17.6
15.4
4.00
3.96
mmol/l
1.51
274
2455
291
2725
3.89
4.56
24.4
18.9
256.90
253.45
e9/l
0.41
283
2633
157
1196
1.66
4.45
5.1
6.3
1.23
1.22
mmol/l
1.12
131
1028
291
2727
3.86
4.40
24.5
19.0
133.52
133.84
g/l
0.15
286
2675
291
2726
3.87
4.39
24.4
18.9
4.41
4.45
e12/l
0.95
282
2626
262
2309
2.11
4.39
5.9
4.8
1.85
2.49
mu/l
0.63
240
2080
132
965
1.66
4.37
2.1
2.0
100.84
97.72
pmol/l
0.27
60
482
42
216
2.10
4.33
3.9
3.1
—
—
—
0
0
133
982
1.64
4.19
3.2
2.5
100.21
110.66
ug/l
0.39
121
908
258
2272
2.01
4.16
5.8
5.6
38.78
39.87
mmol/mol
1.75
242
2066
290
2722
3.44
4.09
24.2
18.9
40.02
39.62
%
0.61
263
2537
10
20
5.13
3.72
1.1
1.2
—
—
—
0
0
285
2635
2.87
3.68
11.8
9.4
24.51
24.38
u/l
0.04
274
2530
270
2445
2.11
3.59
4.7
4.2
4.77
4.76
mmol/l
0.08
250
2235
15
52
2.98
3.52
1.1
1.8
—
—
—
0
0
267
2425
1.97
3.26
4.5
4.2
1.57
1.54
mmol/l
0.66
248
2198
110
818
1.55
3.16
3.3
2.8
—
—
—
0
0
18
75
2.49
3.03
1.5
1.9
—
—
—
0
0
272
2503
1.99
2.92
5.3
4.8
2.79
2.80
mmol/l
0.05
253
2282
280
2604
2.25
2.92
18.6
15.5
73.84
74.83
umol/l
0.30
280
2604
50
321
1.67
2.60
2.4
2.3
2.38
2.35
g/l
0.11
44
299
40
242
1.75
2.57
2.1
4.9
238.91
232.22
u/l
0.22
35
229
87
640
1.51
2.55
1.6
1.6
1.31
1.31
mmol/l
0.02
72
523
118
923
1.46
2.55
3.5
3.5
20.82
79.49
ng/l
0.90
73
647
255
2327
1.66
2.48
4.1
3.8
1.30
1.26
mmol/l
0.41
235
2103
18
83
2.24
2.46
1.7
2.0
—
—
—
0
0
10
32
3.20
2.46
4.0
2.5
4.41
4.38
e9/l
—
10
32
263
2423
1.73
2.42
5.0
4.5
5.78
5.97
mmol/l
2.39
238
2193
10
34
3.01
2.30
4.0
3.1
62.40
59.85
%
—
10
34
234
2106
1.52
2.28
18.3
15.5
15.55
15.04
%
0.57
229
2070
69
495
1.51
2.26
2.4
2.1
—
—
—
0
0
68
488
1.51
2.22
1.7
1.7
1.34
1.17
mg/l
0.20
52
364
152
1276
1.39
2.10
4.9
6.8
9.77
10.92
umol/l
1.35
144
1207
63
450
1.51
2.10
1.7
1.6
1242.75
1207.89
nmol/l
0.11
52
319
5
10
5.06
2.08
1.6
2.2
—
—
—
0
0
46
307
1.59
2.07
2.4
2.3
20.91
22.14
%
0.24
39
258
96
749
1.42
2.02
3.0
3.6
2.07
6.68
mg/mmol
2.76
50
462
96
752
1.41
1.97
2.5
2.5
68.99
64.48
u/l
0.19
86
690
109
874
1.39
1.95
2.6
3.5
2.36
2.37
mmol/l
0.27
95
762
54
379
1.52
1.95
1.7
1.9
—
—
—
0
0
174
1505
1.38
1.95
3.6
3.0
42.38
44.02
u/l
0.14
162
1385
136
1139
1.36
1.83
4.8
3.7
0.00
0.01
estimate
0.50
26
213
137
1150
1.35
1.82
4.8
3.7
0.00
0.03
estimate
0.80
26
193
7
23
3.09
1.81
1.6
1.3
—
—
—
0
0
136
1143
1.35
1.78
6.1
5.2
0.00
0.00
estimate
-0.00
27
198
7
25
2.84
1.66
1.1
1.6
—
—
—
0
0
7
25
2.84
1.66
1.1
1.6
—
—
—
0
0
7
25
2.84
1.66
1.1
1.6
—
—
—
0
0
41
283
1.52
1.61
3.7
5.0
1.08
1.06
mmol/l
0.12
36
255
11
50
2.25
1.59
1.3
1.5
—
—
—
0
0
7
27
2.63
1.52
1.1
1.5
—
—
—
0
0
7
27
2.63
1.52
1.1
1.5
—
—
—
0
0
48
350
1.44
1.45
2.7
2.5
3.67
3.29
e6/l
0.10
22
191
68
530
1.37
1.41
1.9
1.7
429.65
13889337.99
pmol/l
0.50
57
432
77
615
1.34
1.37
5.6
3.7
0.00
0.01
estimate
0.50
27
196
50
373
1.41
1.34
2.6
2.4
1.40
1.17
e6/l
0.14
24
212
57
436
1.38
1.33
3.4
3.6
258.22
426.65
ng/l
0.33
46
343
64
499
1.36
1.33
5.7
3.8
1.02
1.02
kg/l
0.29
15
68
6
24
2.53
1.31
1.0
1.3
—
—
—
0
0
13
69
1.92
1.30
1.7
1.8
—
—
—
0
0
89
734
1.30
1.26
3.0
3.2
35.01
29.76
u/l
0.64
81
699
5
19
2.66
1.22
2.6
1.3
—
—
—
0
0
107
908
1.28
1.21
5.2
3.8
—
—
—
0
0
6
26
2.33
1.19
1.2
1.6
—
—
—
0
0
5
20
2.52
1.15
1.2
1.1
—
—
—
0
0
57
449
1.33
1.11
1.5
1.4
—
—
—
0
0
247
2342
1.32
1.01
15.0
12.3
78.85
78.69
ml/min/173m2
0.04
210
1898
6
120
0.49
0.95
1.3
1.2
—
—
—
0
0
6
27
2.25
0.94
1.2
1.5
—
—
—
0
0
152
1374
1.22
0.92
2.7
2.8
—
—
—
0
0
27
194
1.43
0.92
2.3
3.6
1.24
1.23
mmol/l
0.18
21
164
24
169
1.46
0.91
1.1
1.2
110.61
143.06
iu/ml
—
8
71
53
431
1.28
0.84
5.5
4.5
2.47
3.07
ug/l
0.25
47
384
59
487
1.26
0.83
2.0
3.0
2.43
2.47
mmol/l
2.31
49
431
74
629
1.23
0.81
3.0
2.8
0.67
0.57
e6/l
0.12
58
472
9
54
1.69
0.75
2.1
1.3
—
—
—
0
0
7
39
1.81
0.73
1.0
1.1
—
—
—
0
0
35
280
1.28
0.64
6.1
7.2
—
—
—
0
0
8
50
1.62
0.62
1.3
1.4
—
—
—
0
0
8
50
1.62
0.62
1.3
1.4
—
—
—
0
0
34
273
1.28
0.61
1.6
1.8
—
—
—
0
0
8
51
1.58
0.61
1.4
1.5
—
—
—
0
0
18
131
1.40
0.60
1.6
1.7
—
—
—
0
0
0
22
0.00
0.59
0.0
3.2
—
—
—
0
0
6
35
1.73
0.58
1.0
1.3
33.84
12.15
u/l
—
6
30
8
54
1.49
0.57
1.4
1.5
—
—
—
0
0
17
124
1.39
0.57
1.2
1.3
—
37.44
—
0
9
6
36
1.68
0.57
1.0
1.4
—
—
—
0
0
34
278
1.25
0.54
1.7
1.8
—
—
—
0
0
9
62
1.47
0.53
2.9
1.5
—
—
—
0
0
6
40
1.51
0.52
1.5
1.1
—
—
—
0
0
7
45
1.57
0.49
1.3
1.6
—
—
—
0
0
22
174
1.29
0.46
3.1
3.4
17.24
78.06
u/ml
1.67
22
168
37
313
1.21
0.45
5.4
4.2
34.43
33.50
%
0.26
30
200
21
166
1.29
0.44
2.0
2.7
60.17
59.68
ml/min/173m2
0.03
12
62
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
18
142
1.28
0.39
2.3
2.4
—
18.48
—
0
9
5
35
1.44
0.39
4.2
4.0
70.88
102.73
u/ml
—
5
35
5
36
1.40
0.38
1.0
1.5
—
—
—
0
0
5
36
1.40
0.38
1.0
1.5
—
—
—
0
0
9
68
1.33
0.38
1.6
2.7
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
9
68
1.33
0.38
4.2
2.9
0.58
0.37
u/ml
—
9
40
10
72
1.40
0.37
1.4
1.4
—
—
—
0
0
5
37
1.36
0.37
1.6
1.6
—
—
—
0
0
13
99
1.33
0.36
1.2
1.9
—
—
—
0
0
6
44
1.37
0.34
1.0
1.2
—
—
—
0
0
11
82
1.35
0.34
2.5
1.6
—
—
—
0
0
23
192
1.21
0.33
2.9
2.8
185.30
191.99
ng/l
0.04
23
181
30
258
1.18
0.32
3.6
6.6
0.76
1.24
mmol/l
0.33
25
208
38
339
1.14
0.27
1.5
1.4
—
—
—
0
0
5
75
0.66
0.26
1.4
1.2
—
—
—
0
0
5
75
0.66
0.26
1.4
1.2
—
—
—
0
0
9
72
1.26
0.26
1.0
3.5
—
2.74
—
0
9
9
73
1.24
0.25
1.1
1.0
—
1.09
—
0
7
17
143
1.20
0.24
3.1
2.0
—
—
—
0
0
17
200
0.84
0.23
1.9
2.7
4.69
4.45
kpa
0.18
17
190
5
39
1.29
0.23
5.2
4.2
424.00
360.12
umol/l
—
5
34
20
172
1.17
0.22
1.5
1.4
—
—
—
0
0
10
79
1.28
0.22
1.2
1.1
—
—
—
0
0
31
277
1.13
0.22
3.6
6.0
103.06
104.04
mmol/l
0.55
31
277
5
42
1.19
0.21
1.2
1.4
—
—
—
0
0
5
42
1.19
0.21
1.2
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
6
51
1.18
0.19
2.0
1.3
1.33
2.69
e6/l
—
6
39
6
51
1.18
0.19
2.0
1.4
63.67
126.71
e6/l
—
6
41
7
63
1.11
0.17
1.0
4.4
1163.57
1355.42
u/ml
—
7
58
9
109
0.82
0.13
1.8
1.5
—
—
—
0
0
13
114
1.15
0.12
2.9
3.5
24.62
24.35
mmol/l
0.09
13
109
6
70
0.85
0.07
1.2
1.3
—
—
—
0
0
14
129
1.09
0.05
4.8
7.0
0.46
0.69
%
2.22
14
129
16
149
1.08
0.05
1.1
1.4
—
—
—
0
0
22
209
1.06
0.04
3.7
7.2
121.77
119.59
g/l
0.15
22
204
15
159
0.94
0.03
3.5
2.0
—
—
—
0
0
23
238
0.96
0.02
2.9
3.3
5.94
5.84
kpa
0.24
23
227
11
117
0.94
0.02
1.1
1.0
—
—
—
0
0
13
128
1.02
0.00
4.7
7.0
1.53
1.54
%
0.01
13
128
36
358
1.01
0.00
5.2
4.2
19.99
21.26
%
0.35
20
178
20
197
1.02
0.00
1.5
1.8
—
—
—
0
0
53
534
0.99
0.00
1.3
1.2
0.62
0.98
u/ml
1.38
19
131
0
7
0.00
0.00
0.0
1.0
—
99.57
—
0
7
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
6.7
—
179.22
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
-0.00
1.9
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
60
1.00
-0.00
2.0
1.3
373.00
442.93
mg/l
—
6
55
0
9
0.00
-0.00
0.0
1.0
—
1314.11
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
2.0
1.3
72.00
381.40
pmol/l
—
6
68
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_HALLUDEFORMOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_HALLUDEFORMOTH | 0.675 [0.54, 0.85] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.581 |
During the follow-up period (1.1.1998 — 31.12.2019), 85 out of 970 females with M13_HALLUDEFORMOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_HALLUDEFORMOTH | 0.93 [0.7, 1.24] | 0.625 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 341 males with M13_HALLUDEFORMOTH died.
Mortality risk
Mortality risk for people of age
years, who have M13_HALLUDEFORMOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.058% | 0.114% |
| 5 | 0.403% | 1.004% |
| 10 | 1.009% | 2.475% |
| 15 | 2.078% | 4.616% |
| 20 | 3.681% | 7.893% |
Relationships between endpoints
↥Index endpoint: M13_HALLUDEFORMOTH – Other deformity of hallux (acquired)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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