Respiratory disorders in diseases classified elsewhere

RESP_ILL_DIS_CLASS_ELSEWHERE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J99*
  • Cause of death: ICD-10 J99*

2 out of 7 registries used, show all original rules.

501

4. Check minimum number of events

None

501

5. Include endpoints

None

501

6. Filter based on genotype QC (FinnGen only)

491

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2217 1242 966
Only index persons 1831 1044 787
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.03
Only index persons 0.03 0.04 0.03
Median age at first event (years)
Whole population 65.05 65.35 64.68
Only index persons 64.02 64.19 63.78

-FinnGen-

Key figures

All Female Male
Number of individuals 491 292 199
Unadjusted period prevalence (%) 0.10 0.10 0.09
Median age at first event (years) 62.60 61.33 64.47

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
501
Matched controls
5010
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L04AX01
ATC
azathioprine; systemic
49.3
307.7
239
91
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
45.4
307.7
380
324
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
29.8
270.0
204
113
L04AA06
ATC
mycophenolic acid; systemic
67.0
255.8
144
30
P01BA02
ATC
hydroxychloroquine; oral
16.1
206.8
227
245
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
187.6
168
*
L04AX03
ATC
methotrexate; systemic
13.3
174.6
214
266
TGC00
NOMESCO Finland
Bronchial lavation
28.3
171.5
123
57
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
14.6
156.4
166
165
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
33.4
153.3
102
38
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
32.6
151.9
102
39
M31.3
ICD-10 Finland
Wegener granulomatosis
261.5
151.2
148
8
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
13.3
146.1
165
179
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
22.9
145.1
113
63
UGC12
NOMESCO Finland
Flexible bronchoscopy
11.9
140.2
173
212
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
13.1
129.9
143
148
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
9.9
127.4
187
284
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
48.8
126.8
75
18
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
9.4
122.7
380
1259
H02AB06
ATC
prednisolone; systemic
17.0
121.6
454
1817
M05BA04
ATC
alendronic acid; oral
9.5
111.9
162
239
GD1AD
NOMESCO Finland
Thorax CT examination
11.7
109.3
128
143
L01BA01
ATC
methotrexate; systemic
17.2
108.7
96
68
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
21.0
108.4
86
49
J99.0*M05.1
ICD-10 Finland
Rheumatoid lung disease
+∞
106.1
98
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
9.5
96.4
133
183
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
9.5
85.1
115
153
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
31.4
84.2
56
20
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.8
80.4
393
1743
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
+∞
78.2
73
*
XG410
NOMESCO Finland
Flow-volume spirometry
10.8
73.8
87
96
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
10.0
72.2
90
107
J18.9
ICD-10 Finland
Pneumonia, unspecified
5.0
70.1
247
816
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
11.8
66.5
72
70
ZX120
NOMESCO Finland
Intravenous
6.3
63.6
129
263
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
61.8
58
*
L04AA13
ATC
[U] leflunomide
14.1
61.7
59
47
A07EC01
ATC
sulfasalazine; oral, rectal
6.7
61.1
112
206
DHA10
NOMESCO Finland
Biopsy of cavity of nose
26.0
60.8
43
18
J99.1*M35.0
ICD-10 Finland
Respiratory disorders in sicca syndrome [Sjögren]
+∞
60.7
57
*
L88
ICPC
Rheumatoid/seropositive arthritis
9.9
59.2
73
85
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
10.8
59.1
68
72
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
21.7
55.3
42
21
J99.0
ICD-10 Finland
Rheumatoid lung disease
+∞
52.0
49
*
L04AD01
ATC
ciclosporin; systemic
17.5
50.1
42
26
R50.9
ICD-10 Finland
Fever, unspecified
4.6
49.7
152
434
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
7.0
49.5
83
138
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
11.1
48.6
54
54
J99.1*M33.2
ICD-10 Finland
Respiratory disorders in polymyositis
+∞
42.3
40
*
H02AB07
ATC
prednisone; oral
4.2
41.9
138
412
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
41.2
39
*
J01MA14
ATC
moxifloxacin; systemic
4.9
40.4
103
251
J99.1*M34.8
ICD-10 Finland
Respiratory disorders in systemic: sclerosis
+∞
39.1
37
*
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
8.8
38.6
51
64
M33.2
ICD-10 Finland
Polymyositis
144.6
38.3
40
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.9
37.2
92
218
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.0
37.1
91
214
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
9.7
35.6
43
48
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
9.4
35.4
44
51
1XC02, ,
NOMESCO Finland
50.8
35.3
42
9
J01MA12
ATC
levofloxacin; systemic
3.5
35.0
158
578
J99.1*M32.1
ICD-10 Finland
Respiratory disorders in systemic: lupus erythematosus
+∞
34.8
33
*
M05.1
ICD-10 Finland
Rheumatoid lung disease
+∞
33.7
32
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.4
33.7
73
154
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.3
32.9
97
263
UDH02
NOMESCO Finland
Rhinopharyngoscopy
4.9
32.0
79
186
R06.0
ICD-10 Finland
Dyspnoea
3.0
30.8
208
956
L01AA01
ATC
cyclophosphamide; systemic
72.7
30.3
34
5
TPH04
NOMESCO Finland
Cathetrisation of vein
3.1
28.6
169
716
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
6.6
28.5
48
79
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.6
28.3
111
366
NH3EA
NOMESCO Finland
Feet X-ray examination with load
10.3
27.9
32
33
M33.9
ICD-10 Finland
Dermatopolymyositis, unspecified
153.6
27.9
29
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.9
26.9
92
276
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.9
26.5
184
845
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
26.7
25.6
35
14
C03CA01
ATC
furosemide; systemic
2.6
23.9
204
1032
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
8.6
23.7
31
38
A02BC02
ATC
pantoprazole; systemic
3.0
23.3
394
2759
H02AB04
ATC
methylprednisolone; systemic
3.1
23.2
114
429
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
7.8
23.2
33
45
J99.1*M33.9
ICD-10 Finland
Respiratory disorders in dermatopolymyositis
+∞
23.1
22
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.0
23.0
125
498
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
8.6
22.9
30
37
J96.1
ICD-10 Finland
Chronic respiratory failure
7.4
22.8
34
49
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
7.5
21.9
32
45
M05BA07
ATC
risedronic acid; oral
6.1
21.3
38
66
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
62.8
21.1
24
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.5
21.0
82
267
M13.9
ICD-10 Finland
Arthritis, unspecified
3.8
20.4
69
204
M33.1
ICD-10 Finland
Other dermatomyositis
76.7
19.8
22
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
5.6
19.7
39
75
M34.0
ICD-10 Finland
Progressive systemic sclerosis
207.9
19.7
20
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.4
19.7
267
1632
L04AA01
ATC
[U] ciclosporin
17.6
19.4
30
18
R81
ICPC
Pneumonia
5.7
19.3
37
69
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
7.5
19.3
28
39
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
6.9
19.0
30
46
M05BB03
ATC
alendronic acid and colecalciferol; oral
6.5
18.7
31
50
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
197.1
18.7
19
*
M35.1
ICD-10 Finland
Other overlap syndromes
31.4
18.5
24
8
R03AK08
ATC
formoterol and beclometasone; inhalant
4.5
18.3
46
109
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
7.9
18.0
25
33
ZX108
NOMESCO Finland
Inhalation
23.8
17.9
25
11
H04.10
ICD-10 Finland
Dry eye syndrome
3.0
17.9
88
328
M34.8
ICD-10 Finland
Other forms of systemic sclerosis
+∞
17.8
17
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
5.0
17.3
39
84
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.3
17.3
72
243
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
93.2
16.7
18
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.4
16.5
63
201
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
41.6
16.4
20
5
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
17.5
16.2
25
15
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.5
16.0
125
589
H65.3
ICD-10 Finland
Chronic mucoid otitis media
6.6
16.0
26
41
WZC30
NOMESCO Finland
Teaching
2.6
15.9
110
490
NG1DA
NOMESCO Finland
X-ray of knees
7.2
15.8
24
35
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
17.9
15.8
24
14
1AA01, ,
NOMESCO Finland
+∞
15.7
15
*
SPAT1255
SPAT
Intravenous administration of medicine
3.7
15.7
53
156
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
15.3
81
314
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
5.4
15.2
31
61
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
20.8
15.2
22
11
GX1K5
NOMESCO Finland
Diffusion capacity
24.3
15.2
21
9
C08CA05
ATC
nifedipine; systemic
3.5
15.1
54
165
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
32.8
14.9
19
6
SPAT1229
SPAT
Assessment of need for aid
3.3
14.9
60
198
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
14.8
180
1021
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.1
14.8
289
1965
M05BX04
ATC
denosumab; parenteral
3.5
14.7
54
168
J01FF01
ATC
clindamycin; systemic
2.2
14.5
165
911
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
31.0
14.0
18
6
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
13.8
140
735
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.9
13.8
25
44
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
6.7
13.8
22
34
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
13.6
13
*
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
4.6
13.5
33
76
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
13.5
120
595
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
143.7
13.5
14
*
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
18.9
13.5
20
11
M34.1
ICD-10 Finland
CR(E)ST syndrome
26.6
13.4
18
7
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
14.3
13.4
22
16
WW200
NOMESCO Finland
Immunization
6.0
13.3
24
42
R03AC02
ATC
salbutamol; inhalant
2.0
13.1
301
2132
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
17.3
13.1
20
12
L04AB01
ATC
etanercept; parenteral
12.0
12.9
23
20
J31.0
ICD-10 Finland
Chronic rhinitis
2.9
12.9
63
233
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
12.8
231
1500
A01AB09
ATC
miconazole; local oral
2.9
12.7
65
246
WZA10
NOMESCO Finland
Extensive medical or dental certificate
9.7
12.6
25
27
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
12.5
110
542
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.2
12.4
34
86
J34.8
ICD-10 Finland
Other specified disorders of nose and nasal sinuses
12.8
12.2
21
17
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
5.4
12.1
24
46
M60.9
ICD-10 Finland
Myositis, unspecified
21.9
12.1
17
8
R04.2
ICD-10 Finland
Haemoptysis
4.3
12.0
31
75
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
9.3
11.9
24
27
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.6
11.9
78
336
J05AB11
ATC
valaciclovir; oral
2.4
11.8
96
456
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.1
11.7
50
171
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
66.5
11.7
13
*
M01CB01
ATC
sodium aurothiomalate; parenteral
11.5
11.6
21
19
J99.8*M45
ICD-10 Finland
Respiratory disorders in ankylosing spondylitis
+∞
11.5
11
*
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.6
11.3
39
116
NJ3BG
NOMESCO Finland
MRI examination of extremities with high intensity magnet
25.7
11.2
15
6
A07AA02
ATC
nystatin; oral
3.2
11.2
47
159
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
44.3
11.0
13
*
R03BB04
ATC
tiotropium bromide; inhalant
2.6
10.7
69
294
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
14.6
10.5
17
12
L04AB04
ATC
adalimumab; parenteral
5.6
10.5
20
37
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.2
10.5
42
138
R03BA08
ATC
ciclesonide; inhalant
2.7
10.5
58
229
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
+∞
10.4
10
*
J01AA02
ATC
doxycycline; systemic
2.1
10.4
402
3283
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.0
10.3
46
161
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
19.3
10.3
15
8
A02BC01
ATC
omeprazole; systemic
2.0
10.3
158
955
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
7.7
10.3
23
31
H26.3
ICD-10 Finland
Drug-induced cataract
13.5
10.2
17
13
XG466
NOMESCO Finland
Sleep oxymetry
4.1
10.2
28
71
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.5
10.2
66
282
L99
ICPC
Musculoskeletal disease other
5.2
10.1
21
42
NF1AA
NOMESCO Finland
Hip X-ray examination
2.6
10.1
60
245
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
40.9
10.0
12
*
G04BE03
ATC
sildenafil; oral
9.8
9.8
19
20
ZXA10
NOMESCO Finland
Bilateral
2.1
9.8
116
639
M05BA06
ATC
ibandronic acid; systemic
4.9
9.6
21
44
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.9
9.4
47
175
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
18.0
9.4
14
8
M31.7
ICD-10 Finland
Microscopic polyangiitis
101.9
9.4
10
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
5.3
9.4
19
37
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.0
9.4
42
147
C02KX04
ATC
macitentan; oral
+∞
9.4
9
*
S97
ICPC
Chronic ulcer skin
2.9
9.4
46
170
XX9XE
NOMESCO Finland
Other ultrasound examination
11.0
9.3
17
16
H65.2
ICD-10 Finland
Chronic serous otitis media
7.5
9.3
21
29
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
4.3
9.3
24
58
J01CA04
ATC
amoxicillin; systemic
2.1
9.3
411
3436
J47
ICD-10 Finland
Bronchiectasis
4.9
9.1
20
42
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.3
9.0
75
358
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
9.0
59
253
GX1D5
NOMESCO Finland
Flow volume spirometry
24.5
8.9
12
5
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
8.8
130
770
M01CB03
ATC
auranofin; oral
14.4
8.7
14
10
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
8.7
113
640
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
50.9
8.7
10
*
B02.9
ICD-10 Finland
Zoster without complication
2.7
8.7
48
189
WX892
NOMESCO Finland
Monitored bed care
2.7
8.6
49
196
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
10.3
8.6
16
16
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.7
8.5
27
76
XPX04
NOMESCO Finland
Angioscopy
28.0
8.5
11
*
R60.9
ICD-10 Finland
Oedema, unspecified
3.0
8.5
37
128
M34
ICD-10 Finland
Systemic sclerosis
+∞
8.4
8
*
WW400
NOMESCO Finland
Plasmaferesis
+∞
8.4
8
*
4464A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Wegener's granulomatosis
+∞
8.4
8
*
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.6
8.3
28
82
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
9.7
8.3
16
17
GD1UN
NOMESCO Finland
Lung circulation SPECT
14.8
8.2
13
9
A41.9
ICD-10 Finland
Sepsis, unspecified
3.6
8.2
27
78
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.9
8.2
38
136
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
8.2
151
959
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
8.3
8.1
17
21
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
12.0
8.1
14
12
XF622
NOMESCO Finland
Measurement of minute volume of heart
33.9
8.1
10
*
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.7
8.1
43
166
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.0
8.1
23
60
M81.4
ICD-10 Finland
Drug-induced osteoporosis
22.4
8.0
11
5
C07AB07
ATC
bisoprolol; oral
1.7
8.0
257
1906
A03
ICPC
Fever
2.1
8.0
86
454
E0000UV, ,
ATC
1.7
8.0
212
1492
SPAT1104
SPAT
Monitoring of emergency patient
2.8
7.9
41
156
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
11.0
7.8
14
13
R28
ICPC
Limited function/disability (R)
7.1
7.8
18
26
NDL52
NOMESCO Finland
Tenosynovectomy of hand
9.6
7.8
15
16
UJF32
NOMESCO Finland
Coloscopy
1.8
7.8
142
897
Z94.2
ICD-10 Finland
Lung transplant status
45.7
7.7
9
*
127
Kela drug reimbursment
Transplant complication
7.6
7.7
17
23
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.6
7.7
18
40
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
7.6
79
411
H02AB09
ATC
hydrocortisone; systemic
4.3
7.5
19
45
J01DB01
ATC
cefalexin; oral
1.9
7.5
412
3527
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
7.4
200
1407
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
81.3
7.4
8
*
WX726
NOMESCO Finland
High-flow oxygen therapy
81.3
7.4
8
*
L28
ICPC
Limited function/disability (L)
2.0
7.4
97
549
UDM02
NOMESCO Finland
Sinoscopy
4.1
7.4
20
50
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.5
7.4
47
199
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
3.5
7.3
25
74
GD2SN
NOMESCO Finland
Lung ventilation SPECT
11.1
7.3
13
12
3AC01, ,
NOMESCO Finland
11.1
7.3
13
12
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
6.4
7.3
18
29
WX002
NOMESCO Finland
Sedation and analgesia
1.9
7.3
109
645
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
7.3
230
1687
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.6
7.2
24
70
L01EX09
ATC
nintedanib; oral
30.5
7.2
9
*
M95.0
ICD-10 Finland
Acquired deformity of nose
20.4
7.2
10
5
J45.1
ICD-10 Finland
Nonallergic asthma
2.5
7.1
46
196
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.2
7.1
59
281
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
12.3
7.1
12
10
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.9
7.1
92
519
S18
ICPC
Laceration/cut
1.7
7.0
234
1735
WX202
NOMESCO Finland
Supraclavicular plexus blockade
6.5
7.0
17
27
Z2446
NOMESCO Finland
Social worker
2.6
7.0
42
173
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.7
6.9
22
62
M35.3
ICD-10 Finland
Polymyalgia rheumatica
3.0
6.9
31
109
Z3231
NOMESCO Finland
Registered nurse
1.7
6.9
143
934
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.8
6.8
33
121
J12.8
ICD-10 Finland
Other viral pneumonia
11.1
6.8
12
11
M05BA01
ATC
etidronic acid; systemic
11.1
6.8
12
11
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
11.1
6.8
12
11
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
3.3
6.8
25
78
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.6
6.8
22
63
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
40.6
6.8
8
*
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
40.6
6.8
8
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.0
6.8
30
105
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.2
6.7
60
294
UJF92
NOMESCO Finland
Capsular endoscopy
5.6
6.7
18
33
JN4CD
NOMESCO Finland
Very extensive body CT
3.1
6.6
27
90
J05AB01
ATC
aciclovir; systemic
1.8
6.6
120
753
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
7.0
6.6
15
22
JN4AD
NOMESCO Finland
Body CT examination
2.2
6.5
60
298
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
6.5
51
237
ZXE00
NOMESCO Finland
One hour or less
1.6
6.5
195
1400
SPAT1254
SPAT
Administration of medicine
2.0
6.5
78
429
J96.0
ICD-10 Finland
Acute respiratory failure
7.5
6.4
14
19
GDG10
NOMESCO Finland
Bilateral transplantation of lung
70.7
6.4
7
*
K05.31
ICD-10 Finland
Periodontitis pronounced
2.1
6.4
59
293
356
Kela drug reimbursment
Nintedanib and pirfenidone
14.5
6.4
10
7
GX2C5
NOMESCO Finland
Short-lasting oximetry
14.5
6.4
10
7
J93.8
ICD-10 Finland
Other pneumothorax
14.5
6.4
10
7
B01AB05
ATC
enoxaparin; parenteral
1.7
6.4
168
1166
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
3.5
6.4
21
61
N02AX02
ATC
tramadol; systemic, rectal
1.6
6.3
214
1581
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.3
6.3
49
227
NXL00
NOMESCO Finland
Biopsy of muscle
18.3
6.3
9
5
Z3226
NOMESCO Finland
Physiotherapist
1.8
6.3
100
602
J01MA02
ATC
ciprofloxacin; systemic
1.6
6.3
193
1392
J990, M058,
ICD-10 Finland
+∞
6.3
6
*
XQ860
NOMESCO Finland
Laser Doppler measurement/scan of capillary perfusion
+∞
6.3
6
*
C02KX01
ATC
bosentan; oral
+∞
6.3
6
*
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.2
6.2
24
77
C08CA01
ATC
amlodipine; oral
1.6
6.2
195
1411
M35.8
ICD-10 Finland
Other specified systemic involvement of connective tissue
27.0
6.2
8
*
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
27.0
6.2
8
*
SBA00
NOMESCO Finland
Microbiological examinations
4.1
6.2
17
43
M45
ICD-10 Finland
Ankylosing spondylitis
4.1
6.2
17
43
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
4.1
6.2
17
43
SPAT1097
SPAT
Recording of ECG
1.9
6.2
81
457
R4180
NOMESCO Finland
Podiatric therapy
6.4
6.2
15
24
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.6
6.2
36
146
TEA00
NOMESCO Finland
Biopsy of lip
7.8
6.2
13
17
SPAT1262
SPAT
Handing over of treatment supplies
1.9
6.2
91
535
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
12.7
6.1
10
8
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
6.1
100
607
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
8.8
6.1
12
14
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
3.4
6.1
21
63
SAA03
NOMESCO Finland
Extended examination of mouth
1.6
6.1
188
1356

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
232
181
23.01
260.35
11.2
1.5
21.57
8.36
u/ml
—
103
5
162
143
16.26
164.73
4.2
1.6
243.53
207.50
titre
—
17
8
254
541
8.49
128.33
1.9
1.4
875.00
500.66
titre
2.32
104
122
179
256
10.32
128.10
2.5
1.7
1.17
1.60
g/l
0.73
169
234
121
114
13.68
116.24
1.8
1.3
5.13
2.81
u/ml
0.65
33
16
121
116
13.43
114.89
1.8
1.3
7.77
7.29
u/ml
0.03
49
21
123
124
12.82
112.92
1.8
1.3
28.84
21.44
u/ml
—
17
7
102
82
15.36
107.61
3.1
1.2
222.67
—
titre
—
30
0
107
97
13.76
104.91
1.7
1.2
33.39
2.63
u/ml
—
22
7
448
1946
13.31
103.97
22.9
6.1
—
—
—
0
0
97
78
15.18
102.15
4.8
1.4
—
—
—
0
0
126
161
10.12
96.86
1.7
1.3
5.30
3.02
u/ml
—
17
9
452
2074
13.06
95.95
22.2
5.6
0.04
0.04
e9/l
1.01
445
1813
451
2065
12.86
95.93
22.3
5.6
0.65
0.58
e9/l
7.93
444
1800
103
101
12.58
95.69
1.7
1.2
44.35
—
u/ml
—
10
0
452
2119
12.59
92.26
22.4
5.6
1.65
1.94
e9/l
3.97
446
1897
454
2143
12.92
91.85
23.1
5.8
0.18
0.19
e9/l
0.49
446
1903
58
23
28.39
84.14
1.2
1.1
—
—
—
0
0
67
38
20.20
84.14
1.8
1.3
0.35
0.38
g/l
0.17
48
28
67
38
20.20
84.14
1.8
1.3
6.04
6.64
g/l
0.47
48
29
67
38
20.20
84.14
1.8
1.3
2.31
2.77
g/l
0.77
48
28
68
40
19.51
83.95
1.9
1.3
—
—
—
0
0
77
63
14.26
79.69
2.0
1.7
0.75
0.77
g/l
0.03
55
51
87
93
11.11
75.60
1.8
1.3
79.63
31.58
u/ml
1.44
23
11
455
2422
10.57
72.50
25.5
9.0
4.99
4.10
e9/l
10.61
446
2140
158
357
6.00
70.29
7.3
4.0
0.72
0.81
%
0.27
82
131
133
265
6.47
67.35
1.3
1.4
—
—
—
0
0
150
335
5.96
67.34
7.5
4.0
0.07
0.14
%
0.68
74
108
143
318
5.89
64.27
7.2
4.0
0.31
0.51
%
1.03
68
105
164
418
5.35
63.06
1.5
1.5
—
—
—
0
0
63
62
11.48
57.55
3.0
3.1
—
—
—
0
0
179
529
4.71
56.78
1.5
1.6
—
—
—
0
0
135
317
5.46
56.55
7.6
4.1
0.02
1.08
%
0.56
60
90
272
1102
4.21
56.04
6.6
4.1
—
—
—
0
0
44
28
17.13
51.78
2.0
1.2
224.55
68.00
titre
—
11
5
333
1703
3.85
45.73
3.4
2.3
82.13
78.19
nmol/l
1.88
320
1513
55
62
9.84
45.40
2.7
3.0
—
—
—
0
0
374
2072
4.18
45.37
12.3
6.8
1.22
1.22
mmol/l
0.16
322
1769
51
52
10.81
45.24
1.6
1.2
—
—
—
0
0
56
67
9.28
44.16
4.9
3.4
4.66
4.68
e9/l
0.02
56
67
372
2075
4.08
44.15
7.9
3.7
0.00
0.00
estimate
0.50
103
434
272
1248
3.58
43.67
5.2
3.0
1105.91
1244.73
ng/l
0.41
254
1069
57
71
8.93
43.54
4.9
3.9
60.79
58.66
%
0.41
57
71
208
807
3.70
43.37
2.2
1.5
2.27
2.40
g/l
0.45
175
483
349
1886
3.80
43.01
11.3
5.9
1.21
1.22
mmol/l
0.39
337
1723
373
2110
4.01
42.73
7.9
3.7
0.00
0.01
estimate
0.50
101
391
370
2082
3.97
42.73
10.4
4.9
0.00
0.00
estimate
-0.00
101
403
153
505
3.92
40.18
2.4
1.4
—
—
—
0
0
292
1459
3.40
39.73
9.5
3.7
29.87
88.01
e6/l
2.92
242
1041
459
3110
6.68
38.76
19.6
4.2
17.77
12.36
mm/h
9.60
454
2864
164
593
3.62
37.28
3.1
2.1
—
—
—
0
0
437
2889
5.01
37.06
13.3
4.3
—
—
—
0
0
260
1254
3.23
36.74
6.2
3.8
7.40
7.40
ph
0.01
61
238
308
1654
3.24
35.88
7.1
3.5
6.13
5.87
ph
—
8
122
124
385
3.95
35.12
2.0
2.0
335.89
375.06
nmol/l
0.53
114
350
239
1120
3.17
35.11
7.9
2.9
—
—
—
0
0
257
1257
3.14
35.00
6.6
2.1
140.96
315.98
u/l
1.50
250
1190
165
634
3.39
33.64
1.5
1.8
—
—
—
0
0
182
743
3.28
33.58
1.5
1.3
78.14
36.34
iu/ml
1.67
98
235
145
521
3.51
32.81
8.5
5.4
1.07
1.03
mmol/l
0.85
140
482
97
270
4.22
31.75
5.9
6.2
—
—
—
0
0
32
29
11.72
30.51
2.4
2.0
403.78
534.21
e6/l
0.69
27
24
234
1154
2.93
30.31
8.3
2.9
0.24
0.49
e6/l
1.54
215
864
172
716
3.14
30.23
1.5
1.3
45.05
10.17
u/ml
2.58
67
263
247
1266
2.88
29.58
8.5
3.1
17.78
97.21
e6/l
0.91
227
972
131
471
3.41
29.29
2.7
1.6
—
—
—
0
0
312
1825
2.88
28.75
27.5
9.3
0.00
0.00
e9/l
0.27
298
1505
108
352
3.64
28.03
2.2
3.0
66.26
66.52
g/l
0.11
100
321
307
1796
2.83
28.02
7.1
4.6
33.58
35.52
g/l
7.39
294
1687
352
2217
2.98
27.80
9.6
6.2
9.60
11.30
umol/l
4.20
345
2104
161
673
3.05
27.77
3.3
2.3
11.07
12.89
umol/l
2.72
156
626
201
953
2.85
27.46
7.9
3.6
—
—
—
0
0
88
264
3.83
25.69
7.0
3.7
7.43
7.40
ph
1.34
13
34
124
464
3.22
25.67
11.9
8.2
5.02
5.07
kpa
0.24
118
444
71
184
4.33
25.32
2.2
2.1
1.70
1.50
g/l
0.78
65
164
141
578
3.00
24.85
3.4
2.3
20.29
22.65
%
1.15
126
498
94
302
3.60
24.76
1.9
2.4
—
—
—
0
0
83
252
3.75
23.73
1.6
1.2
149.00
242.47
u/ml
0.42
73
224
120
466
3.07
23.11
11.9
8.2
1.60
1.31
mmol/l
0.33
102
380
179
861
2.68
23.05
6.7
2.8
527.49
538.92
mosm/kgh2o
0.36
173
744
54
123
4.80
22.56
1.9
2.1
10.57
12.61
mg/l
0.69
48
112
205
1079
2.52
21.64
5.2
2.7
350.06
6420.60
umol/l
4.34
193
945
271
1637
2.43
20.92
5.6
3.6
56.14
56.53
ng/l
0.01
227
1160
198
1046
2.48
20.51
17.1
6.7
—
—
—
0
0
28
37
7.96
20.14
1.5
1.2
—
—
—
0
0
212
1165
2.42
20.03
9.2
3.9
0.00
0.00
estimate
-0.00
100
392
143
660
2.63
19.57
6.1
3.4
0.82
0.82
mmol/l
0.02
136
628
115
475
2.84
19.54
5.3
2.5
1.81
1.80
%
0.07
107
429
38
72
5.63
19.50
1.5
1.6
—
—
—
0
0
194
1039
2.42
19.26
3.1
2.1
3.56
3.14
mg/l
1.17
180
889
383
2766
2.63
19.09
8.7
4.4
8.50
2251.75
e6/l
—
6
52
25
9
29.13
18.90
1.4
2.0
—
—
—
0
0
146
692
2.57
18.83
6.0
2.6
0.47
1.06
e6/l
4.58
114
377
30
47
6.73
18.58
4.3
3.2
—
—
—
0
0
27
14
20.31
18.38
1.2
1.1
—
—
—
0
0
27
14
20.31
18.38
1.2
1.1
—
—
—
0
0
27
14
20.31
18.38
1.2
1.1
—
—
—
0
0
65
198
3.62
18.34
7.0
3.8
—
—
—
0
0
349
2442
2.41
18.18
9.2
4.7
6.68
6.64
mmol/l
0.13
339
2278
25
33
7.92
17.97
1.6
1.4
32.20
30.36
%
0.08
18
22
39
82
5.07
17.84
6.8
3.4
—
—
—
0
0
57
162
3.84
17.78
8.4
3.9
—
—
—
0
0
299
1971
2.28
17.75
19.0
13.2
1.20
1.24
inr
0.37
94
587
30
50
6.32
17.51
1.5
1.3
59.33
65.45
%
0.32
18
36
91
351
2.95
17.41
3.4
2.7
69.65
70.62
e9/l
0.09
70
273
22
7
32.77
17.17
1.1
1.3
—
—
—
0
0
90
349
2.92
17.03
9.6
3.3
—
—
—
0
0
84
321
2.94
16.29
14.2
8.0
—
—
—
0
0
51
143
3.86
16.19
5.4
3.0
0.37
0.20
g/l
0.75
28
50
37
81
4.85
16.14
3.6
2.3
14.89
16.04
%
0.97
19
42
22
9
25.47
16.13
2.3
1.7
—
—
—
0
0
37
83
4.73
15.68
8.8
3.7
3.50
2.31
mmol/l
1.78
29
50
31
60
5.44
15.52
1.4
1.2
—
—
—
0
0
32
65
5.19
15.20
1.2
1.2
2.62
3.75
u/ml
0.55
13
28
39
94
4.41
15.13
2.1
1.7
14134.56
17175.17
e6/l
0.11
32
70
32
66
5.11
14.94
4.6
3.1
1.03
1.05
%
0.02
32
60
229
1435
2.10
14.49
3.7
3.3
2.32
2.35
mmol/l
2.82
213
1266
267
1794
2.05
13.74
4.0
2.7
209.77
127.94
ug/l
1.28
255
1657
34
80
4.49
13.59
5.7
2.4
—
—
—
0
0
86
368
2.61
13.32
4.9
3.4
2.58
2.05
mmol/l
0.74
80
302
21
14
15.59
13.20
1.8
1.1
7.99
8.84
ug/l
0.30
21
14
25
48
5.43
12.61
2.4
1.7
87.18
89.95
%
0.92
25
48
162
937
2.08
12.29
2.8
1.7
1.87
1.19
mg/l
1.53
132
737
44
138
3.40
11.80
3.2
3.9
46.19
99.83
mg/l
0.58
33
108
44
138
3.40
11.80
3.2
3.9
48.96
27.88
mg/l
0.63
33
107
196
1229
1.98
11.77
6.8
3.1
558.20
206.15
mg/l
0.48
158
780
22
40
5.71
11.74
1.0
1.2
—
—
—
0
0
69
283
2.67
11.57
4.3
2.6
10.18
7.74
e9/l
0.16
62
231
201
1298
1.92
10.87
6.8
3.0
7.09
7.45
mmol/l
0.63
185
1084
83
383
2.40
10.86
2.3
1.4
—
—
—
0
0
71
313
2.48
10.24
2.0
1.4
—
—
—
0
0
199
1305
1.87
10.09
3.9
3.0
—
—
—
0
0
72
322
2.44
10.06
4.8
3.6
67.21
79.03
ng/l
1.15
67
287
198
1300
1.86
9.97
8.3
3.7
11.05
7.79
mg/mmol
0.71
154
802
77
357
2.37
9.94
10.2
3.6
—
—
—
0
0
33
96
3.61
9.92
1.3
1.6
—
—
—
0
0
469
4136
3.10
9.54
45.6
14.2
19.06
22.71
mg/l
2.50
461
3289
201
1355
1.81
9.10
5.0
3.2
34.88
31.41
u/l
0.56
196
1299
34
107
3.34
9.08
2.5
4.3
—
—
—
0
0
115
648
2.01
9.04
4.0
1.9
29.03
29.50
s
0.45
115
629
162
1031
1.84
8.80
5.4
3.7
92.76
91.29
%
0.28
157
1010
31
94
3.45
8.77
3.2
2.0
121.90
131.86
g/l
1.52
20
70
196
1326
1.79
8.67
2.7
2.5
55.29
59.68
u/l
0.55
189
1228
176
1157
1.80
8.55
7.3
3.3
—
—
—
0
0
114
653
1.97
8.51
7.2
2.9
2.41
2.72
e6/l
0.10
82
342
35
117
3.14
8.49
2.7
3.2
—
—
—
0
0
14
12
11.96
8.12
2.1
1.3
—
—
—
0
0
25
70
3.71
7.95
1.6
1.3
106.80
100.43
u/ml
—
5
14
40
150
2.81
7.94
1.6
2.1
10.54
10.14
g/l
0.16
35
135
16
19
8.66
7.86
1.0
1.2
—
—
—
0
0
26
77
3.51
7.63
2.3
2.6
0.78
0.90
nmol/l
0.39
20
57
19
31
6.33
7.61
2.3
2.9
47.18
43.20
%
0.42
11
20
26
78
3.46
7.48
1.7
1.3
—
—
—
0
0
12
9
13.62
7.42
1.8
1.2
—
—
—
0
0
25
74
3.50
7.34
2.0
1.5
—
—
—
0
0
127
791
1.81
7.21
2.0
1.7
1380.55
1164.45
nmol/l
1.09
104
586
21
58
3.74
6.82
1.6
1.6
—
—
—
0
0
67
344
2.09
6.69
2.9
2.3
13.40
6.61
ug/l
0.94
57
302
19
51
3.83
6.42
1.2
1.1
—
—
—
0
0
71
379
2.02
6.39
2.2
2.3
0.20
0.21
g/l
0.34
64
356
29
103
2.93
6.37
1.2
1.1
—
—
—
0
0
12
13
9.42
6.32
2.3
1.2
—
—
—
0
0
74
405
1.97
6.20
8.1
4.1
—
—
—
0
0
225
1691
1.60
6.13
2.5
2.1
—
—
—
0
0
41
178
2.42
6.11
2.6
1.9
—
—
—
0
0
9
6
15.24
5.92
1.0
1.2
—
—
—
0
0
33
132
2.61
5.82
1.6
2.1
36.46
38.00
g/l
0.99
28
118
11
12
9.34
5.81
3.4
4.3
55.50
48.08
%
0.33
11
12
12
16
7.65
5.66
3.3
1.8
73.46
55.02
ug/l
0.54
12
16
9
8
11.43
5.31
1.0
1.0
—
—
—
0
0
9
8
11.43
5.31
1.2
1.1
—
—
—
0
0
13
22
6.04
5.25
2.2
4.5
—
—
—
0
0
137
942
1.63
5.24
10.0
4.0
1.02
1.02
kg/l
0.55
15
133
16
35
4.69
5.22
1.1
1.2
—
—
—
0
0
16
36
4.56
5.09
2.1
1.2
—
—
—
0
0
8
6
13.52
5.09
8.6
2.0
—
—
—
0
0
15
32
4.80
5.03
1.2
1.1
—
—
—
0
0
21
72
3.00
4.93
1.2
1.3
241.60
248.56
u/ml
0.04
15
43
172
1268
1.54
4.82
5.0
3.9
—
—
—
0
0
15
42
3.65
4.80
1.0
1.1
—
—
—
0
0
247
1973
1.50
4.71
3.6
2.5
—
—
—
0
0
129
898
1.59
4.63
1.7
1.7
61947375.31
6693886.06
pmol/l
0.42
113
747
29
124
2.42
4.50
1.3
1.3
—
—
—
0
0
15
44
3.48
4.50
4.6
2.5
0.88
1.41
g/24h
—
10
24
41
204
2.10
4.47
4.7
2.4
1.53
1.18
%
1.52
41
204
65
380
1.82
4.45
1.3
1.4
—
—
—
0
0
13
28
4.74
4.40
1.3
1.2
0.43
0.31
u/ml
—
8
19
32
145
2.29
4.37
1.4
1.2
—
—
—
0
0
93
605
1.66
4.37
1.3
1.2
—
—
—
0
0
9
12
7.61
4.37
1.0
1.3
—
—
—
0
0
37
179
2.15
4.33
1.1
1.3
—
—
—
0
0
8
9
9.01
4.29
1.3
1.6
—
—
—
0
0
23
91
2.60
4.19
1.3
1.2
18.71
4.67
e6/l
0.82
17
73
46
247
1.95
4.09
1.4
1.3
—
—
—
0
0
115
802
1.56
4.05
2.4
2.9
2.46
2.46
mmol/l
0.19
96
703
15
48
3.19
3.96
1.9
1.7
—
—
—
0
0
461
4292
1.93
3.95
37.1
16.4
139.32
139.71
mmol/l
2.46
455
4176
10
19
5.35
3.84
1.1
1.2
1.08
1.10
ratio
—
5
5
127
917
1.52
3.80
1.3
1.2
0.68
1.27
u/ml
1.30
32
249
463
4329
1.92
3.73
28.8
13.4
—
—
—
0
0
461
4305
1.89
3.72
37.2
16.5
3.94
3.97
mmol/l
2.62
454
4186
113
807
1.52
3.54
5.5
3.9
383.84
279.65
ng/l
0.29
101
640
20
82
2.50
3.42
3.7
2.6
—
—
—
0
0
171
1334
1.43
3.40
3.5
2.3
—
—
—
0
0
14
348
0.39
3.30
1.0
1.4
—
—
—
0
0
42
236
1.85
3.29
6.4
2.9
0.11
0.18
e6/l
0.58
42
230
208
1688
1.40
3.28
2.1
2.0
97.20
94.86
pmol/l
0.33
130
854
13
39
3.39
3.24
2.5
2.6
—
—
—
0
0
14
49
2.91
3.21
1.6
1.5
42.93
32.08
g/l
1.85
14
42
70
458
1.61
3.21
2.9
3.0
7.13
9.83
umol/l
0.87
62
405
7
11
6.44
3.19
1.7
2.0
—
—
—
0
0
14
50
2.85
3.11
1.2
1.1
—
—
—
0
0
37
204
1.88
3.08
19.6
11.8
—
—
—
0
0
12
36
3.39
3.03
1.3
1.3
—
—
—
0
0
19
81
2.40
3.02
1.2
1.3
—
—
—
0
0
5
5
10.08
2.98
1.0
1.0
—
—
—
0
0
27
136
2.04
2.91
14.4
10.0
—
—
—
0
0
14
52
2.74
2.91
37.9
6.1
6.70
6.50
mmol/l
0.13
14
43
7
13
5.44
2.88
1.0
1.1
—
—
—
0
0
8
19
4.26
2.69
4.8
2.7
1549.13
836.89
u/ml
—
8
19
8
19
4.26
2.69
1.1
1.0
—
—
—
0
0
9
24
3.80
2.68
1.6
1.3
—
—
—
0
0
12
43
2.83
2.66
1.0
1.2
—
—
—
0
0
7
15
4.72
2.60
1.0
1.1
—
—
—
0
0
7
15
4.72
2.60
1.3
2.8
—
—
—
0
0
11
37
3.02
2.50
1.4
1.3
—
—
—
0
0
9
223
0.39
2.49
1.8
1.4
—
—
—
0
0
115
1463
0.72
2.42
3.1
2.9
—
—
—
0
0
9
27
3.37
2.40
1.4
1.3
—
—
—
0
0
131
1029
1.37
2.40
1.7
1.6
18.69
20.79
nmol/l
0.91
123
881
27
147
1.88
2.38
2.5
2.8
—
—
—
0
0
11
40
2.79
2.28
1.9
1.4
—
—
—
0
0
8
24
3.37
2.19
5.0
1.9
7.97
9.62
mmol/l
—
8
24
350
3197
1.31
2.09
4.6
4.0
15.31
14.78
pmol/l
3.29
329
2893
11
43
2.59
2.09
3.4
2.6
—
—
—
0
0
13
56
2.36
2.06
1.5
2.1
—
—
—
0
0
7
20
3.53
2.06
3.0
2.2
—
—
—
0
0
7
21
3.37
1.97
4.1
6.1
—
—
—
0
0
8
27
2.99
1.94
4.5
3.0
—
—
—
0
0
11
45
2.48
1.94
1.2
1.1
—
—
—
0
0
12
52
2.34
1.89
1.8
1.8
29.25
33.08
pg
1.20
12
52
7
22
3.21
1.88
1.7
1.2
—
—
—
0
0
9
34
2.68
1.87
2.0
1.2
—
—
—
0
0
68
501
1.41
1.82
2.1
2.3
267.73
145.05
ug/g
0.92
58
391
324
2958
1.27
1.79
6.1
3.9
—
—
—
0
0
6
18
3.36
1.75
1.0
1.3
—
—
—
0
0
8
32
2.52
1.60
1.1
1.1
338.50
238.81
mg/l
—
8
27
7
26
2.72
1.58
2.3
4.0
—
—
—
0
0
7
26
2.72
1.58
1.3
1.3
—
—
—
0
0
6
20
3.02
1.58
3.2
2.3
—
—
—
0
0
8
33
2.45
1.54
1.5
1.1
60.92
36.42
mg/l
—
8
26
133
1116
1.26
1.47
1.6
1.4
—
—
—
0
0
7
28
2.52
1.45
1.0
1.3
2.24
1.93
mmol/l
—
7
28
7
28
2.52
1.45
1.3
1.5
—
—
—
0
0
12
59
2.06
1.44
1.2
1.0
—
—
—
0
0
9
39
2.33
1.43
4.1
2.8
—
—
—
0
0
44
314
1.44
1.43
1.1
1.2
—
—
—
0
0
390
4093
0.79
1.39
4.9
4.4
1.48
1.49
mmol/l
0.07
361
3780
375
3952
0.80
1.38
4.4
4.0
1.45
1.27
mmol/l
3.94
351
3627
6
23
2.63
1.37
1.5
1.3
—
—
—
0
0
472
4591
1.49
1.27
57.0
21.0
39.47
40.06
%
1.75
449
4282
10
188
0.52
1.23
1.2
1.7
—
—
—
0
0
14
78
1.82
1.22
1.2
1.8
4.73
4.74
mmol/24h
0.00
14
66
13
71
1.85
1.20
1.2
1.1
—
—
—
0
0
6
126
0.47
1.18
5.2
4.4
—
—
—
0
0
395
4117
0.81
1.13
4.8
4.5
4.58
4.67
mmol/l
0.96
362
3821
5
21
2.39
1.09
4.6
1.8
—
—
—
0
0
8
41
1.97
1.09
3.3
2.5
—
—
—
0
0
133
1153
1.21
1.08
1.9
1.6
1.54
1.36
mmol/l
1.77
113
976
294
2733
1.18
1.07
4.4
3.1
74.39
48.20
u/l
1.24
279
2556
405
4198
0.82
0.99
5.2
5.0
2.62
2.75
mmol/l
2.35
375
3875
6
119
0.50
0.95
1.2
1.5
309.00
325.93
mu/l
—
6
110
6
120
0.49
0.94
1.2
1.3
—
—
—
0
0
6
28
2.16
0.91
2.5
1.5
74.00
74.21
umol/l
—
6
28
403
3873
1.21
0.91
6.5
5.8
40.36
39.76
mmol/mol
0.32
385
3612
40
310
1.32
0.85
1.4
1.6
—
—
—
0
0
16
105
1.54
0.82
3.7
2.6
—
—
—
0
0
10
58
1.74
0.80
1.3
1.1
—
—
—
0
0
10
58
1.74
0.80
1.3
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
162.28
—
0
24
6
33
1.83
0.79
1.3
1.2
—
—
—
0
0
5
97
0.51
0.79
1.0
1.3
—
—
—
0
0
0
26
0.00
0.78
0.0
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
20.8
—
1738.23
—
0
26
0
26
0.00
0.78
0.0
14.8
—
981.92
—
0
26
18
123
1.48
0.78
1.6
1.3
292.42
292.61
ug/g
0.00
11
66
398
3839
1.18
0.77
5.4
4.8
1.97
1.91
mu/l
0.49
370
3507
36
287
1.27
0.66
3.3
2.6
—
—
—
0
0
395
4066
0.87
0.64
5.4
4.6
5.74
5.95
mmol/l
2.64
360
3725
8
49
1.64
0.62
1.3
1.1
—
—
—
0
0
12
80
1.51
0.60
1.3
1.6
—
—
—
0
0
28
220
1.29
0.58
2.2
2.3
—
—
—
0
0
37
450
0.81
0.58
1.7
1.7
—
—
—
0
0
8
54
1.49
0.57
1.4
1.1
—
—
—
0
0
12
84
1.44
0.49
3.4
3.0
—
—
—
0
0
53
459
1.17
0.47
2.3
4.1
9.08
30.70
ug/l
0.64
42
387
5
81
0.61
0.46
1.2
1.7
—
—
—
0
0
7
51
1.38
0.44
1.4
1.2
—
—
—
0
0
7
51
1.38
0.44
1.4
1.1
—
—
—
0
0
56
493
1.15
0.42
1.4
1.3
—
—
—
0
0
5
33
1.52
0.41
1.2
1.1
—
3.31
—
0
6
0
15
0.00
0.41
0.0
1.1
—
0.20
—
0
7
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
2.5
—
73.50
—
0
12
11
148
0.74
0.39
1.4
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
1.52
—
0
19
9
68
1.33
0.38
4.9
1.8
74.08
59.17
%
—
9
68
9
71
1.27
0.36
1.1
1.2
—
—
—
0
0
6
45
1.34
0.34
1.8
2.0
—
—
—
0
0
6
46
1.31
0.33
1.2
1.3
—
—
—
0
0
19
230
0.82
0.32
2.6
2.9
56.84
58.19
u/ml
0.01
19
222
13
163
0.79
0.30
1.1
1.1
—
—
—
0
0
9
116
0.77
0.27
1.1
1.3
—
—
—
0
0
13
158
0.82
0.24
1.3
1.3
40.29
25.42
iu/l
0.93
13
134
5
39
1.28
0.23
15.6
2.3
15.20
13.23
%
—
5
39
5
41
1.22
0.22
3.2
2.7
—
—
—
0
0
10
123
0.81
0.20
1.1
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
0.18
—
0
5
0
14
0.00
0.20
0.0
1.1
—
0.65
—
0
8
9
114
0.79
0.20
1.2
1.1
—
—
—
0
0
25
281
0.88
0.20
1.1
1.2
—
—
—
0
0
10
122
0.82
0.19
1.1
1.3
—
—
—
0
0
10
122
0.82
0.19
1.1
1.3
—
—
—
0
0
68
723
0.93
0.19
2.9
3.1
0.65
0.77
ug/l
0.88
47
478
10
121
0.82
0.18
1.1
1.3
—
—
—
0
0
24
215
1.12
0.17
6.2
3.6
—
—
—
0
0
39
360
1.09
0.16
1.5
1.4
—
—
—
0
0
26
286
0.90
0.15
1.5
1.2
124.05
152.83
iu/ml
0.19
11
118
50
531
0.94
0.14
1.5
1.3
—
—
—
0
0
14
158
0.88
0.12
1.1
1.1
—
—
—
0
0
5
61
0.82
0.08
5.4
2.7
—
—
—
0
0
5
61
0.82
0.08
5.4
2.7
4.06
4.00
mmol/l
—
5
61
5
61
0.82
0.08
5.4
2.7
107.80
105.51
mmol/l
—
5
61
124
1225
1.02
0.03
4.1
5.1
2.14
2.52
ug/l
0.53
103
1097
18
179
1.01
0.00
1.9
3.1
11.15
1135.20
u/ml
0.81
13
152
5
49
1.02
-0.00
3.8
2.5
3.58
5.83
umol/l
—
5
32
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
17.28
—
0
6
6
59
1.02
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
42.71
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
0.04
—
0
5
0
9
0.00
-0.00
0.0
1.3
—
1.60
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.6
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.2
662.60
291.70
pmol/l
—
5
46
8
85
0.94
-0.00
1.1
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint RESP_ILL_DIS_CLASS_ELSEWHERE and mortality.

Females

Parameter HR [95% CI] p-value
RESP_ILL_DIS_CLASS_ELSEWHERE 3.745 [3.08, 4.55] < 0.001
Birth year 0.994 [0.99, 1.0] 0.194

During the follow-up period (1.1.1998 — 31.12.2019), 396 out of 1005 females with RESP_ILL_DIS_CLASS_ELSEWHERE died.

Males

Parameter HR [95% CI] p-value
RESP_ILL_DIS_CLASS_ELSEWHERE 3.158 [2.5, 3.98] < 0.001
Birth year 0.988 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 342 out of 764 males with RESP_ILL_DIS_CLASS_ELSEWHERE died.

Mortality risk

Mortality risk for people of age

years, who have RESP_ILL_DIS_CLASS_ELSEWHERE.

N-year risk Females Males
1 0.345% 0.573%
5 2.154% 3.715%
10 5.214% 8.745%
15 9.821% 16.302%
20 17.124% 26.876%

Relationships between endpoints

Index endpoint: RESP_ILL_DIS_CLASS_ELSEWHERE – Respiratory disorders in diseases classified elsewhere

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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