Respiratory disorders in diseases classified elsewhere

RESP_ILL_DIS_CLASS_ELSEWHERE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J99*
  • Cause of death: ICD-10 J99*

2 out of 7 registries used, show all original rules.

474

4. Check minimum number of events

None

474

5. Include endpoints

None

474

6. Filter based on genotype QC (FinnGen only)

474

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2217 1242 966
Only index persons 1831 1044 787
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.03
Only index persons 0.03 0.04 0.03
Median age at first event (years)
Whole population 65.05 65.35 64.68
Only index persons 64.02 64.19 63.78

-FinnGen-

Key figures

All Female Male
Number of individuals 474 281 193
Unadjusted period prevalence (%) 0.09 0.10 0.09
Median age at first event (years) 61.90 60.20 64.36

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
416
Matched controls
4159
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
49.5
235.0
316
249
L04AX01
ATC
azathioprine; systemic
50.6
169.4
206
79
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
154.0
138
*
M31.3
ICD-10 Finland
Wegener granulomatosis
894.1
135.8
126
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
33.7
128.3
172
85
P01BA02
ATC
hydroxychloroquine; oral
19.2
112.5
186
168
H02AB06
ATC
prednisolone; systemic
15.2
107.6
369
1419
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
+∞
105.9
97
*
L04AA06
ATC
mycophenolic acid; systemic
56.3
100.5
118
29
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
9.5
94.5
310
979
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
14.7
90.5
166
179
J99.0*M05.1
ICD-10 Finland
Rheumatoid lung disease
+∞
78.7
73
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
15.2
78.4
139
133
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
30.5
78.3
106
46
UGC12
NOMESCO Finland
Flexible bronchoscopy
13.6
78.1
147
161
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
15.1
77.8
138
132
TGC00
NOMESCO Finland
Bronchial lavation
30.2
73.8
100
43
GD1AA
NOMESCO Finland
Thorax X-ray examination
7.2
70.9
322
1347
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
49.1
66.5
80
20
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
10.2
66.4
146
209
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
14.8
65.6
116
106
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
34.0
59.7
78
28
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
57.7
54
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
34.3
56.8
74
26
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
12.1
55.2
107
116
M05BA04
ATC
alendronic acid; oral
9.0
54.9
128
195
J18.9
ICD-10 Finland
Pneumonia, unspecified
5.3
50.4
202
628
J99.1*M35.0
ICD-10 Finland
Respiratory disorders in sicca syndrome [Sjögren]
+∞
48.9
46
*
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
15.0
47.7
82
67
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
9.7
46.5
101
133
XG410
NOMESCO Finland
Flow-volume spirometry
14.7
45.7
79
65
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
57.9
43.8
51
10
J99.0
ICD-10 Finland
Rheumatoid lung disease
+∞
42.4
40
*
M33.2
ICD-10 Finland
Polymyositis
+∞
39.2
37
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
35.3
38.9
50
16
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
10.6
37.5
76
86
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
36.0
34
*
J99.1*M33.2
ICD-10 Finland
Respiratory disorders in polymyositis
+∞
36.0
34
*
A07EC01
ATC
sulfasalazine; oral, rectal
6.7
32.7
90
165
GD1AD
NOMESCO Finland
Thorax CT examination
9.2
31.4
68
86
H02AB07
ATC
prednisone; oral
4.7
31.2
121
331
J99.1*M32.1
ICD-10 Finland
Respiratory disorders in systemic: lupus erythematosus
+∞
30.6
29
*
J99.1*M34.8
ICD-10 Finland
Respiratory disorders in systemic: sclerosis
+∞
29.5
28
*
ZX120
NOMESCO Finland
Intravenous
5.4
29.2
97
223
1XC02
NOMESCO Finland
NA
47.6
29.2
35
8
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
10.5
29.0
58
63
DHA10
NOMESCO Finland
Biopsy of cavity of nose
39.2
28.9
36
10
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
6.9
28.5
75
128
M33.9
ICD-10 Finland
Dermatopolymyositis, unspecified
+∞
27.4
26
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.5
26.0
148
560
R50.9
ICD-10 Finland
Fever, unspecified
4.1
25.7
115
354
L04AA13
ATC
leflunomide; oral
11.7
25.6
48
46
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
10.8
25.6
50
52
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.3
24.8
82
185
L01AA01
ATC
cyclophosphamide; systemic
51.7
24.6
29
6
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
19.6
24.0
36
20
J01MA12
ATC
levofloxacin; systemic
3.4
23.2
134
504
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
11.6
23.0
43
41
J01MA14
ATC
moxifloxacin; systemic
4.8
22.8
82
202
L88
ICPC
Rheumatoid/seropositive arthritis
7.9
22.7
53
75
UDH02
NOMESCO Finland
Rhinopharyngoscopy
5.9
22.6
67
132
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
6.1
22.5
64
120
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.7
22.2
81
202
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
28.2
21.6
29
11
TPH04
NOMESCO Finland
Cathetrisation of vein
3.2
21.4
134
531
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.0
21.3
73
170
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
115.9
20.8
22
*
C03CA01
ATC
furosemide; systemic
2.9
20.5
162
746
R06.0
ICD-10 Finland
Dyspnoea
2.9
20.0
157
718
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
9.2
20.0
42
50
J99.1*M33.9
ICD-10 Finland
Respiratory disorders in dermatopolymyositis
+∞
20.0
19
*
A02BC02
ATC
pantoprazole; systemic
2.8
19.5
312
2158
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.6
19.2
95
312
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.6
19.0
218
1240
M33.1
ICD-10 Finland
Other dermatomyositis
73.4
18.9
21
*
L04AD01
ATC
ciclosporin; systemic
10.8
18.8
36
36
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
55.1
18.1
21
*
M05.1
ICD-10 Finland
Rheumatoid lung disease
+∞
17.8
17
*
M35.1
ICD-10 Finland
Other overlap syndromes
44.0
17.4
21
5
L04AA01
ATC
[U] ciclosporin; systemic
13.0
16.1
28
23
M13.9
ICD-10 Finland
Arthritis, unspecified
4.5
15.8
58
144
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
166.0
15.6
16
*
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
39.7
15.5
19
5
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.1
15.5
64
178
H04.10
ICD-10 Finland
Dry eye syndrome
3.8
15.4
69
206
ZX108
NOMESCO Finland
Inhalation
21.0
15.3
22
11
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
11.5
15.2
28
26
NH3EA
NOMESCO Finland
Feet X-ray examination with load
10.7
15.2
29
29
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.8
14.8
67
202
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
83.1
14.7
16
*
M34.0
ICD-10 Finland
Progressive systemic sclerosis
155.2
14.6
15
*
M34.8
ICD-10 Finland
Other forms of systemic sclerosis
155.2
14.6
15
*
J96.1
ICD-10 Finland
Chronic respiratory failure
9.6
13.9
28
31
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
55.3
13.9
16
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
9.0
13.5
28
33
H02AB04
ATC
methylprednisolone; systemic
2.8
13.5
96
399
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
8.0
13.4
30
40
WZA10
NOMESCO Finland
Long statement of health and health related matters
12.7
13.3
23
19
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
6.5
13.2
34
56
M05BB03
ATC
alendronic acid and colecalciferol; oral
8.5
13.0
28
35
J01FF01
ATC
clindamycin; systemic
2.4
13.0
134
682
M05BA07
ATC
risedronic acid; oral
6.4
13.0
34
57
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
12.8
93
391
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
12.8
12.8
22
18
1AA01
NOMESCO Finland
NA
72.1
12.7
14
*
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
133.9
12.5
13
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
6.6
12.2
31
50
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
6.8
12.1
30
47
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.1
12.0
230
1541
C08CA05
ATC
nifedipine; systemic
4.0
12.0
49
135
J31.0
ICD-10 Finland
Chronic rhinitis
3.7
11.8
52
153
M60.9
ICD-10 Finland
Myositis, unspecified
31.0
11.7
15
5
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
11.6
149
839
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
14.2
11.6
19
14
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
11.5
193
1219
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
123.3
11.5
12
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
12.3
11.4
20
17
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
36.1
11.3
14
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
11.3
114
570
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.3
11.2
59
200
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.5
11.0
98
461
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
18.4
10.8
16
9
J01AA02
ATC
doxycycline; systemic
2.2
10.7
334
2684
M31.0
ICD-10 Finland
Hypersensitivity angiitis
61.6
10.7
12
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
5.2
10.6
32
65
J99.8*M45
ICD-10 Finland
Respiratory disorders in ankylosing spondylitis
+∞
10.5
10
*
R03AC02
ATC
salbutamol; inhalant
2.0
10.4
231
1608
GX1K5
NOMESCO Finland
Diffusion capacity
33.5
10.4
13
*
M34.1
ICD-10 Finland
CR(E)ST syndrome
24.1
10.3
14
6
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
8.2
10.2
22
28
J05AB11
ATC
valaciclovir; oral
2.6
10.2
79
343
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
10.4
10.1
19
19
H26.3
ICD-10 Finland
Drug-induced cataract
15.1
10.1
16
11
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
15.1
10.1
16
11
TDM10
NOMESCO Finland
Puncture of maxillary antrum
5.2
9.9
30
61
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
12.6
9.9
17
14
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.4
9.9
93
444
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
11.0
9.9
18
17
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
9.8
67
269
KA1AE
NOMESCO Finland
Kidney ultrasound examination
8.1
9.7
21
27
H65.3
ICD-10 Finland
Chronic mucoid otitis media
8.7
9.7
20
24
A02BC01
ATC
omeprazole; systemic
2.1
9.6
139
812
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
102.3
9.5
10
*
WZC30
NOMESCO Finland
Teaching
2.6
9.4
76
334
XG466
NOMESCO Finland
Sleep oxymetry
5.5
9.4
27
52
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
9.0
9.4
19
22
SPAT1255
SPAT
Intravenous administration of medicine
3.6
9.4
42
126
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.8
9.3
61
238
NG1DA
NOMESCO Finland
X-ray of knees
7.6
9.3
21
29
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
6.1
9.2
24
41
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.0
9.2
36
96
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.2
9.2
34
86
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
9.4
9.1
18
20
M01CB01
ATC
sodium aurothiomalate; parenteral
10.4
9.1
17
17
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
16.0
9.1
14
9
R03AK08
ATC
formoterol and beclometasone; inhalant
4.8
9.0
29
64
J01CA04
ATC
amoxicillin; systemic
2.1
9.0
336
2771
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.6
8.9
39
115
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
6.2
8.9
23
39
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
14.4
8.7
14
10
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
14.4
8.7
14
10
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
4.0
8.7
34
91
NJ3BG
NOMESCO Finland
MRI examination of extremities with high intensity magnet
16.7
8.6
13
8
A07AA02
ATC
nystatin; oral
3.3
8.6
42
135
J34.8
ICD-10 Finland
Other specified disorders of nose and nasal sinuses
10.3
8.6
16
16
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
8.5
76
355
4464A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Wegener's granulomatosis
+∞
8.4
8
*
M34
ICD-10 Finland
Systemic sclerosis
+∞
8.4
8
*
NF1AA
NOMESCO Finland
Hip X-ray examination
3.0
8.2
48
175
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
5.0
8.2
25
52
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.1
8.2
46
162
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
8.1
80
392
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.7
7.9
56
228
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
13.4
7.9
13
10
H65.2
ICD-10 Finland
Chronic serous otitis media
11.1
7.8
14
13
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.1
7.8
100
550
J01DB01
ATC
cefalexin; oral
2.0
7.8
340
2863
M31.7
ICD-10 Finland
Microscopic polyangiitis
45.9
7.7
9
*
G04BE03
ATC
sildenafil; oral
7.3
7.6
17
24
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
5.8
7.5
20
36
WX002
NOMESCO Finland
Sedation and analgesia
2.1
7.4
94
513
GX1D5
NOMESCO Finland
Flow volume spirometry
81.5
7.4
8
*
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
81.5
7.4
8
*
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
8.6
7.4
15
18
GD2SN
NOMESCO Finland
Lung ventilation SPECT
11.1
7.3
13
12
GD1UN
NOMESCO Finland
Lung circulation SPECT
11.1
7.3
13
12
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
+∞
7.3
7
*
M05BX04
ATC
denosumab; parenteral
3.3
7.3
35
112
M01CB03
ATC
auranofin; oral
12.3
7.1
12
10
3AC01
NOMESCO Finland
NA
12.3
7.1
12
10
A01AB09
ATC
miconazole; local oral
2.6
7.1
51
210
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.3
7.1
34
109
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.9
7.0
42
157
ZXA10
NOMESCO Finland
Bilateral
2.0
6.9
92
510
SPAT1229
SPAT
Assessment of need for aid
2.7
6.9
48
195
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
14.1
6.9
11
8
L04AB01
ATC
etanercept; parenteral
6.9
6.9
16
24
M05BA01
ATC
etidronic acid; systemic
11.2
6.8
12
11
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
11.2
6.8
12
11
R04.2
ICD-10 Finland
Haemoptysis
4.3
6.8
24
59
H19.3*M35.0
ICD-10 Finland
Keratoconjunctivitis sicca
40.7
6.8
8
*
M35.3
ICD-10 Finland
Polymyalgia rheumatica
3.8
6.7
27
75
JN4CD
NOMESCO Finland
Very extensive body CT
3.9
6.7
26
70
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
22.9
6.7
9
*
M05BA06
ATC
ibandronic acid; systemic
6.1
6.7
17
29
S97
ICPC
Chronic ulcer skin
3.4
6.7
31
97
B02.9
ICD-10 Finland
Zoster without complication
3.1
6.7
35
120
N02BE01
ATC
paracetamol; systemic, rectal
2.0
6.6
353
3067
A41.9
ICD-10 Finland
Sepsis, unspecified
4.5
6.6
22
51
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
12.5
6.6
11
9
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
6.6
160
1094
R05
ICD-10 Finland
Cough
2.0
6.5
85
467
R03BB04
ATC
tiotropium bromide; inhalant
2.5
6.5
51
223
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
70.9
6.4
7
*
M35.8
ICD-10 Finland
Other specified systemic involvement of connective tissue
70.9
6.4
7
*
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.5
6.4
28
84
J47
ICD-10 Finland
Bronchiectasis
6.1
6.4
16
27
C07AB07
ATC
bisoprolol; oral
1.7
6.3
200
1469
R4120
NOMESCO Finland
Occupational therapy
3.2
6.3
32
107
H15.1
ICD-10 Finland
Episcleritis
9.5
6.3
12
13
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.8
6.3
25
69
DM1DG
NOMESCO Finland
Paranasal sinuses and face area very extensive MRI examination with high intensity magnet
+∞
6.3
6
*
C02KX01
ATC
bosentan; oral
+∞
6.3
6
*
J990, M058
ICD-10 Finland
NA
+∞
6.3
6
*
M05.3
ICD-10 Finland
Rheumatoid arthritis with involvement of other organs and systems
+∞
6.3
6
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
6.3
49
211
NG2CA
NOMESCO Finland
X-ray of patella with specialised projection
27.1
6.2
8
*
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
27.1
6.2
8
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
6.2
78
423
WX722
NOMESCO Finland
PEEP
3.7
6.2
25
70
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.7
6.2
25
70
R04.0
ICD-10 Finland
Epistaxis
2.9
6.1
36
133
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.7
6.1
40
158
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.8
6.1
129
839
J05AB01
ATC
aciclovir; systemic
1.9
6.1
96
568
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
10.2
6.1
11
11
K05.31
ICD-10 Finland
Periodontitis pronounced
2.5
6.1
48
209
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
6.0
65
331

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
240
508
8.54
122.09
1.9
1.4
852.4
514.4
titre
1.82
97
114
170
243
10.35
121.77
2.5
1.8
1.1
1.6
g/l
0.78
160
224
112
109
13.14
105.18
1.8
1.3
5.2
2.8
u/ml
0.66
32
16
112
111
12.90
103.88
1.8
1.3
3.9
7.3
u/ml
0.38
45
21
114
119
12.30
102.04
1.7
1.3
12.7
24.9
u/ml
—
15
6
91
71
15.62
97.53
5.0
1.4
—
—
—
0
0
425
1931
12.62
91.40
22.6
5.5
0.6
0.6
e9/l
7.11
418
1674
426
1944
12.76
91.08
22.6
5.5
0.0
0.0
e9/l
0.96
419
1689
338
1269
6.80
87.99
19.9
5.6
—
—
—
0
0
426
1984
12.33
87.77
22.7
5.5
1.6
2.0
e9/l
3.98
420
1761
117
154
9.76
87.70
1.7
1.3
5.3
2.7
u/ml
—
17
10
428
2007
12.67
87.42
23.5
5.7
0.2
0.2
e9/l
0.48
420
1776
53
20
29.71
78.16
1.3
1.2
—
—
—
0
0
61
38
18.28
73.11
1.9
1.3
5.9
6.6
g/l
0.62
45
29
61
38
18.28
73.11
1.9
1.3
0.3
0.4
g/l
0.20
45
28
61
38
18.28
73.11
1.9
1.3
2.3
2.8
g/l
0.88
45
28
62
40
17.68
73.02
2.0
1.3
—
—
—
0
0
71
63
13.08
69.80
2.1
1.7
0.8
0.8
g/l
0.01
52
51
429
2278
10.30
68.51
25.8
9.0
5.0
4.1
e9/l
10.34
420
2012
80
90
10.49
66.87
1.8
1.3
80.0
34.7
u/ml
—
21
10
145
328
5.93
64.27
7.1
3.9
0.8
0.9
%
0.12
65
103
137
307
5.87
61.10
7.3
4.0
0.1
0.2
%
0.81
60
94
122
248
6.28
60.33
1.3
1.4
—
—
—
0
0
154
390
5.37
59.69
1.5
1.5
—
—
—
0
0
130
292
5.76
57.57
7.0
3.9
0.4
0.4
%
0.13
49
74
259
1043
4.27
54.11
6.6
4.1
—
—
—
0
0
167
499
4.62
52.06
1.5
1.6
—
—
—
0
0
47
35
14.80
50.91
2.4
2.0
1.0
1.2
e9/l
0.38
28
18
54
51
11.82
50.62
3.0
3.1
—
—
—
0
0
122
290
5.32
50.19
7.5
4.1
0.0
0.1
%
0.45
55
79
42
28
16.36
48.24
2.0
1.2
227.0
68.0
titre
—
10
5
49
49
11.04
44.08
1.6
1.2
—
—
—
0
0
212
834
3.79
43.83
6.3
2.4
4.1
6.0
e6/l
0.81
207
737
313
1592
3.84
43.43
3.4
2.3
81.6
78.0
nmol/l
1.60
300
1417
351
1939
4.12
42.68
12.7
6.8
1.2
1.2
mmol/l
0.13
300
1649
52
60
9.61
42.17
2.6
3.0
—
—
—
0
0
53
63
9.35
42.01
4.3
3.5
4.7
4.7
e9/l
0.04
53
63
350
1943
4.06
41.93
7.9
3.6
0.0
0.0
estimate
0.00
89
379
54
66
9.11
41.89
4.4
4.0
61.3
59.2
%
0.41
54
66
328
1769
3.77
40.49
11.7
5.9
1.2
1.2
mmol/l
0.46
315
1612
35
23
16.35
40.36
2.6
2.3
23.9
13.1
%
0.94
15
14
196
766
3.66
40.33
2.2
1.4
2.3
2.4
g/l
0.35
164
464
255
1177
3.52
40.32
5.4
3.0
1154.2
1201.3
ng/l
0.11
238
1004
350
1982
3.93
39.76
7.9
3.7
0.0
0.0
estimate
0.50
90
372
347
1958
3.88
39.55
10.4
4.9
0.0
0.0
estimate
0.00
90
382
146
477
3.98
39.04
2.4
1.4
—
—
—
0
0
42
42
10.88
37.67
2.0
1.6
—
—
—
0
0
42
42
10.88
37.67
2.0
1.6
—
—
—
0
0
42
42
10.88
37.67
2.0
1.6
—
—
—
0
0
42
42
10.88
37.67
2.0
1.6
—
—
—
0
0
277
1392
3.38
37.26
9.6
3.6
31.4
78.7
e6/l
2.27
229
993
432
2932
6.34
35.97
19.7
4.1
17.6
12.2
mm/h
9.11
427
2695
246
1174
3.28
35.66
6.3
3.9
7.4
7.4
ph
0.12
53
226
154
555
3.63
35.21
3.1
2.1
—
—
—
0
0
96
248
4.60
34.93
5.8
6.2
—
—
—
0
0
412
2721
4.93
34.92
13.5
4.3
—
—
—
0
0
119
364
4.03
34.55
2.0
2.0
339.0
372.7
nmol/l
0.41
109
334
228
1067
3.19
33.72
7.9
2.9
—
—
—
0
0
244
1188
3.17
33.67
6.8
2.1
143.6
326.0
u/l
1.46
237
1122
156
595
3.42
32.28
1.5
1.8
—
—
—
0
0
137
486
3.56
31.73
8.5
5.4
1.1
1.0
mmol/l
0.79
132
452
199
892
3.12
31.21
15.0
4.4
—
—
—
0
0
32
29
11.76
30.53
2.4
2.0
403.8
534.2
e6/l
0.69
27
24
23
12
20.09
29.36
1.2
1.2
—
—
—
0
0
23
12
20.09
29.36
1.2
1.2
—
—
—
0
0
23
12
20.09
29.36
1.2
1.2
—
—
—
0
0
167
700
3.14
29.10
1.5
1.3
78.0
36.7
iu/ml
1.41
87
216
222
1097
2.93
28.67
8.3
2.9
0.3
0.5
e6/l
1.35
202
813
193
891
2.97
28.16
7.9
3.6
—
—
—
0
0
235
1207
2.88
28.08
8.5
3.1
17.9
101.0
e6/l
0.90
215
923
291
1684
2.89
27.51
7.3
4.7
33.6
35.5
g/l
6.77
279
1580
121
434
3.40
27.14
12.1
8.3
5.0
5.1
kpa
0.60
115
416
123
448
3.36
26.89
2.6
1.6
—
—
—
0
0
68
165
4.64
26.46
2.1
2.1
1.7
1.5
g/l
0.76
62
147
150
626
3.04
25.93
3.3
2.2
11.2
12.8
umol/l
2.14
144
574
331
2090
2.93
25.83
9.8
6.2
9.7
11.3
umol/l
3.84
326
1983
157
674
2.99
25.78
1.4
1.3
40.4
10.6
u/ml
1.92
59
250
290
1719
2.77
25.42
27.3
9.5
0.0
0.0
e9/l
0.29
276
1410
99
328
3.55
25.00
2.3
2.7
66.3
66.7
g/l
0.20
91
301
118
438
3.26
24.83
12.1
8.3
1.6
1.3
mmol/l
0.31
101
356
85
256
3.83
24.72
7.2
3.8
5.1
5.1
kpa
0.13
80
239
132
536
3.03
23.71
3.3
2.2
20.6
22.6
%
0.85
117
460
83
253
3.76
23.67
7.1
3.8
7.4
7.4
ph
1.25
12
32
27
29
9.81
22.84
2.1
1.9
571.4
702.4
e6/l
0.28
16
12
169
801
2.72
22.57
6.5
2.7
529.9
547.8
mosm/kgh2o
0.59
163
686
86
277
3.57
22.54
2.0
2.3
—
—
—
0
0
52
118
4.83
21.85
1.9
2.1
10.5
12.5
mg/l
0.62
46
107
193
1014
2.52
20.49
5.2
2.7
352.2
6883.4
umol/l
4.34
181
878
76
240
3.58
20.44
1.6
1.2
135.4
247.0
u/ml
0.51
67
214
189
987
2.52
20.28
17.2
6.7
—
—
—
0
0
138
621
2.72
20.08
6.2
3.4
0.8
0.8
mmol/l
0.04
132
589
263
1603
2.44
19.98
12.7
8.4
1.2
1.2
inr
0.30
80
482
365
2605
2.74
19.42
8.8
4.4
8.5
2290.2
e6/l
—
6
51
108
439
2.89
18.97
5.4
2.6
1.8
1.8
%
0.01
101
396
335
2310
2.54
18.89
9.4
4.7
6.7
6.6
mmol/l
0.09
325
2151
27
37
7.68
18.84
1.4
1.2
—
—
—
0
0
253
1554
2.35
18.38
5.5
3.6
59.7
58.8
ng/l
0.01
210
1093
88
326
3.09
18.19
9.6
3.2
—
—
—
0
0
29
45
6.80
18.13
4.3
3.3
—
—
—
0
0
35
66
5.65
18.06
1.5
1.5
—
—
—
0
0
196
1090
2.36
17.80
9.3
3.9
0.0
0.0
estimate
0.00
89
371
54
149
3.96
17.59
8.7
3.7
—
—
—
0
0
51
136
4.08
17.40
5.4
3.1
0.4
0.2
g/l
0.73
28
48
179
968
2.36
17.22
3.0
2.1
3.5
3.1
mg/l
0.95
167
832
62
191
3.58
17.22
7.1
3.9
—
—
—
0
0
84
320
2.98
16.45
3.4
2.7
68.2
70.4
e9/l
0.24
65
248
21
7
31.29
16.24
1.1
1.3
—
—
—
0
0
36
78
4.91
15.91
6.7
3.4
—
—
—
0
0
80
305
2.95
15.61
14.8
8.1
—
—
—
0
0
60
195
3.38
15.30
15.4
9.9
24.8
24.6
mmol/l
0.19
53
185
220
1347
2.18
15.24
3.7
3.3
2.3
2.4
mmol/l
2.52
201
1181
20
8
26.00
14.80
2.4
1.8
—
—
—
0
0
31
63
5.19
14.73
1.1
1.2
2.6
3.7
u/ml
0.49
13
27
26
45
6.06
14.61
1.4
1.4
55.2
64.5
%
0.45
14
32
29
56
5.45
14.56
1.3
1.2
—
—
—
0
0
36
84
4.56
14.55
2.1
1.7
5484.7
18651.6
e6/l
1.17
29
62
20
9
23.12
14.33
1.4
2.0
—
—
—
0
0
21
31
7.04
13.69
1.5
1.5
34.5
32.6
%
0.07
14
20
14
12
11.99
13.58
2.1
1.3
—
—
—
0
0
34
81
4.44
13.39
8.4
3.7
3.6
2.3
mmol/l
1.78
26
49
33
77
4.53
13.34
3.4
2.3
15.1
15.9
%
0.60
17
40
85
365
2.62
13.12
4.2
3.4
—
—
—
0
0
81
345
2.63
12.69
4.9
3.4
2.5
2.0
mmol/l
0.59
71
271
16
19
8.68
12.44
1.0
1.2
—
—
—
0
0
189
1159
2.05
12.40
6.8
3.1
567.8
214.9
mg/l
0.47
155
731
32
78
4.33
12.24
5.7
2.4
—
—
—
0
0
19
29
6.78
12.00
2.3
3.0
49.2
40.4
%
—
6
10
247
1685
1.97
11.81
4.0
2.7
216.2
126.2
ug/l
1.32
236
1551
194
1223
1.99
11.60
6.8
3.0
7.0
7.5
mmol/l
0.79
179
1016
21
37
5.89
11.57
1.0
1.2
—
—
—
0
0
152
888
2.05
11.18
2.8
1.7
1.9
1.2
mg/l
1.31
124
698
64
260
2.69
10.96
4.5
2.5
4.7
4.0
e9/l
1.07
56
205
69
299
2.53
10.36
2.0
1.5
—
—
—
0
0
22
45
5.08
10.36
2.3
1.8
86.7
89.7
%
0.87
22
45
40
130
3.27
10.16
3.4
3.7
51.8
27.9
mg/l
0.66
30
100
40
130
3.27
10.16
3.4
3.7
47.8
99.8
mg/l
0.51
30
101
189
1228
1.90
9.99
8.4
3.9
11.2
7.2
mg/mmol
0.91
150
753
77
358
2.37
9.92
2.3
1.4
—
—
—
0
0
184
1200
1.87
9.51
3.9
3.0
—
—
—
0
0
31
91
3.58
9.21
1.4
1.6
—
—
—
0
0
72
339
2.33
8.98
10.1
3.7
—
—
—
0
0
110
613
2.03
8.98
4.1
1.9
29.0
29.4
s
0.37
110
597
34
108
3.31
8.96
2.8
3.4
—
—
—
0
0
442
3903
2.96
8.73
46.0
14.1
19.3
22.7
mg/l
2.06
435
3094
11
13
8.64
8.49
2.4
1.2
—
—
—
0
0
154
978
1.85
8.47
5.6
3.7
92.6
91.3
%
0.23
149
958
25
67
3.88
8.45
1.6
1.3
106.8
100.4
u/ml
—
5
14
109
622
1.98
8.27
7.0
2.8
2.5
2.5
e6/l
0.00
77
322
44
171
2.73
8.19
4.8
3.4
24.7
24.3
mmol/l
0.38
36
158
10
11
9.27
8.11
3.2
4.5
55.4
50.5
%
—
10
11
29
89
3.41
8.07
3.0
2.0
123.8
131.1
g/l
0.95
18
66
12
17
7.22
8.03
3.3
1.8
73.5
54.6
ug/l
0.57
12
17
26
75
3.61
7.93
1.7
1.4
—
—
—
0
0
25
71
3.66
7.80
2.3
2.5
0.8
0.9
nmol/l
0.34
19
53
21
53
4.10
7.69
1.6
1.5
—
—
—
0
0
182
1248
1.74
7.57
2.8
2.5
55.1
56.5
u/l
0.25
177
1156
16
33
4.98
7.46
2.1
1.2
—
—
—
0
0
16
33
4.98
7.46
1.1
1.2
—
—
—
0
0
163
1095
1.74
7.22
7.1
3.3
—
—
—
0
0
30
101
3.10
7.21
2.6
4.0
—
—
—
0
0
19
47
4.17
7.14
1.2
1.1
—
—
—
0
0
11
8
14.04
6.92
1.9
1.3
—
—
—
0
0
119
744
1.80
6.68
2.1
1.7
1372.7
1169.4
nmol/l
0.93
98
548
64
326
2.11
6.55
3.0
2.3
14.0
6.7
ug/l
0.98
54
285
23
70
3.40
6.50
2.0
1.4
—
—
—
0
0
134
876
1.74
6.43
9.9
4.0
1.0
1.0
kg/l
0.58
15
122
14
30
4.78
6.25
1.2
1.1
—
—
—
0
0
70
377
2.01
6.17
8.6
4.2
—
—
—
0
0
39
165
2.49
6.15
2.7
1.9
—
—
—
0
0
67
360
2.00
5.94
2.1
2.3
0.2
0.2
g/l
0.21
60
337
18
50
3.70
5.81
1.2
1.3
—
—
—
0
0
211
1589
1.59
5.69
2.6
2.1
—
—
—
0
0
9
7
13.07
5.60
1.2
1.1
—
—
—
0
0
9
7
13.07
5.60
1.0
1.0
—
—
—
0
0
31
123
2.63
5.57
1.6
2.2
36.4
37.8
g/l
0.78
26
108
11
21
5.34
5.55
2.1
4.7
—
—
—
0
0
13
29
4.58
5.54
1.3
1.2
0.4
0.3
u/ml
—
8
18
21
67
3.23
5.53
1.2
1.3
241.6
255.7
u/ml
0.08
15
39
27
100
2.80
5.53
1.2
1.1
—
—
—
0
0
8
5
16.25
5.42
8.6
2.0
—
—
—
0
0
29
115
2.62
5.23
1.3
1.3
—
—
—
0
0
237
1858
1.55
5.22
5.5
4.0
—
—
—
0
0
32
135
2.47
5.10
1.4
1.2
—
—
—
0
0
10
19
5.36
5.06
1.1
1.2
1.1
1.1
ratio
—
5
5
15
41
3.75
4.96
1.0
1.1
—
—
—
0
0
81
494
1.77
4.85
26.3
19.9
1.3
1.3
inr
—
10
66
15
42
3.66
4.80
2.1
2.3
—
—
—
0
0
10
20
5.09
4.79
1.5
1.5
1.2
1.8
u/field
—
10
12
162
1190
1.55
4.65
5.0
3.9
—
—
—
0
0
36
168
2.24
4.60
1.1
1.2
—
—
—
0
0
112
757
1.63
4.58
5.5
3.8
391.4
252.0
ng/l
0.42
99
600
8
8
10.14
4.53
1.3
1.6
—
—
—
0
0
62
357
1.85
4.47
1.3
1.4
—
—
—
0
0
22
84
2.70
4.29
1.3
1.2
18.7
4.9
e6/l
0.80
17
67
7
6
11.81
4.29
1.0
1.2
—
—
—
0
0
110
753
1.60
4.24
2.4
2.9
2.5
2.5
mmol/l
0.20
91
661
38
188
2.11
4.22
4.5
2.4
1.5
1.2
%
1.34
38
188
44
233
1.98
4.08
1.4
1.3
—
—
—
0
0
13
37
3.58
4.07
2.5
2.6
—
—
—
0
0
8
11
7.38
3.87
1.0
1.4
—
—
—
0
0
435
4042
1.93
3.84
37.8
16.3
139.4
139.7
mmol/l
2.00
429
3934
12
34
3.60
3.79
1.3
1.3
—
—
—
0
0
121
869
1.53
3.75
1.3
1.2
0.7
1.3
u/ml
1.21
29
240
37
190
2.03
3.74
19.7
11.9
—
—
—
0
0
164
1257
1.47
3.69
3.6
2.3
—
—
—
0
0
12
337
0.34
3.68
1.0
1.4
—
—
—
0
0
435
4054
1.89
3.63
37.9
16.4
3.9
4.0
mmol/l
2.67
429
3944
9
17
5.37
3.52
1.3
1.1
—
—
g/l
—
0
0
117
845
1.51
3.51
1.7
1.8
67961627.8
7102718.9
pmol/l
0.43
103
704
437
4088
1.88
3.46
28.8
13.4
—
—
—
0
0
84
567
1.59
3.40
1.3
1.2
—
—
—
0
0
7
10
7.08
3.37
1.7
2.1
—
—
—
0
0
11
32
3.50
3.35
3.5
1.3
—
—
—
0
0
27
129
2.16
3.30
14.4
9.3
—
—
—
0
0
197
1591
1.41
3.24
2.1
2.0
97.9
95.3
pmol/l
0.36
124
798
104
1401
0.67
3.23
3.1
2.9
—
—
—
0
0
40
223
1.87
3.22
5.9
2.8
0.1
0.2
e6/l
0.56
40
218
14
49
2.91
3.21
1.2
1.1
—
—
—
0
0
13
44
3.01
3.16
2.1
1.7
—
—
—
0
0
12
39
3.13
3.11
1.0
1.2
—
—
—
0
0
7
12
5.90
3.03
1.0
1.1
—
—
—
0
0
66
433
1.61
3.01
2.9
3.1
7.1
9.7
umol/l
0.82
59
384
7
13
5.45
2.88
1.3
2.8
—
—
—
0
0
18
77
2.39
2.85
1.2
1.3
—
—
—
0
0
11
36
3.10
2.82
1.4
1.3
—
—
—
0
0
8
18
4.50
2.80
4.8
2.6
1549.1
863.2
u/ml
—
8
18
7
14
5.06
2.73
1.0
1.1
—
—
—
0
0
8
19
4.26
2.69
1.1
1.0
—
—
—
0
0
11
38
2.94
2.59
3.4
2.4
—
—
—
0
0
13
50
2.65
2.55
40.7
6.3
6.8
6.5
mmol/l
0.19
13
41
12
46
2.65
2.37
1.7
1.5
42.4
32.1
g/l
1.41
12
41
8
22
3.68
2.37
1.5
1.5
—
—
—
0
0
17
78
2.22
2.34
3.9
2.6
—
—
—
0
0
11
41
2.72
2.29
1.2
1.1
—
—
—
0
0
6
13
4.66
2.28
1.7
2.9
—
—
—
0
0
9
212
0.41
2.25
1.8
1.4
—
—
—
0
0
8
24
3.37
2.19
4.6
3.1
—
—
—
0
0
8
24
3.37
2.19
1.3
1.3
—
—
—
0
0
7
19
3.72
2.16
3.0
2.2
—
—
—
0
0
66
472
1.46
2.07
2.1
2.2
272.3
143.8
ug/g
0.96
57
369
329
2999
1.32
2.03
4.5
3.9
15.3
14.8
pmol/l
2.54
309
2715
120
961
1.33
1.93
1.7
1.6
19.1
20.9
nmol/l
0.68
112
823
6
17
3.56
1.84
1.0
1.3
—
—
—
0
0
12
53
2.30
1.82
1.2
1.0
—
—
—
0
0
9
35
2.60
1.81
4.4
3.1
—
—
—
0
0
364
3858
0.76
1.75
4.8
4.4
1.5
1.5
mmol/l
0.18
338
3564
6
18
3.36
1.75
3.2
2.2
—
—
—
0
0
24
142
1.73
1.68
2.5
2.9
—
—
—
0
0
8
31
2.61
1.66
1.5
1.1
60.9
36.4
mg/l
—
8
25
7
25
2.83
1.65
1.0
1.2
—
—
—
0
0
7
25
2.83
1.65
1.0
1.3
2.2
1.9
mmol/l
—
7
25
43
296
1.50
1.65
1.1
1.2
—
—
—
0
0
8
32
2.53
1.60
2.1
1.3
—
—
—
0
0
6
20
3.02
1.58
4.7
6.3
—
—
—
0
0
351
3725
0.78
1.58
4.4
4.0
1.5
1.3
mmol/l
4.11
330
3422
302
2771
1.25
1.52
6.0
3.9
—
—
—
0
0
6
21
2.88
1.51
1.5
1.3
—
—
—
0
0
127
1059
1.27
1.50
1.6
1.4
—
—
—
0
0
9
37
2.46
1.48
2.1
1.4
—
—
—
0
0
7
28
2.52
1.45
1.3
1.5
—
—
—
0
0
369
3882
0.78
1.45
4.8
4.5
4.6
4.7
mmol/l
0.86
339
3605
11
52
2.14
1.45
1.7
1.7
29.7
33.2
pg
0.96
11
52
15
82
1.86
1.37
3.7
2.2
—
—
—
0
0
5
115
0.43
1.26
5.6
4.5
—
—
—
0
0
379
3959
0.79
1.26
5.2
5.0
2.6
2.8
mmol/l
2.07
352
3656
6
25
2.42
1.24
2.5
4.1
—
—
—
0
0
5
19
2.65
1.22
4.6
1.9
—
—
—
0
0
12
64
1.90
1.19
1.1
1.0
—
—
—
0
0
10
184
0.53
1.16
1.2
1.8
—
—
—
0
0
5
111
0.44
1.14
1.2
1.6
332.6
320.9
mu/l
—
5
103
8
40
2.02
1.12
3.3
2.5
—
—
—
0
0
39
287
1.39
1.11
1.3
1.6
—
—
—
0
0
5
21
2.40
1.09
2.0
1.2
—
—
—
0
0
18
113
1.62
1.07
1.6
1.4
292.4
296.7
ug/g
0.03
11
64
380
3643
1.22
0.94
6.5
5.8
40.5
39.8
mmol/mol
0.36
364
3400
10
55
1.84
0.92
1.3
1.1
—
—
—
0
0
10
55
1.84
0.92
1.3
1.1
—
—
—
0
0
6
30
2.01
0.87
1.3
1.2
—
—
—
0
0
375
3603
1.20
0.84
5.3
4.7
1.9
1.9
mu/l
0.15
348
3292
8
46
1.75
0.83
1.3
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
46.4
—
0
8
0
25
0.00
0.79
0.0
21.6
—
1803.8
—
0
25
0
25
0.00
0.79
0.0
15.3
—
1013.2
—
0
25
35
270
1.32
0.78
3.2
2.6
—
—
—
0
0
122
1087
1.16
0.73
1.9
1.6
1.6
1.4
mmol/l
1.99
105
921
12
76
1.59
0.72
1.3
1.7
—
—
—
0
0
12
76
1.59
0.72
3.4
2.8
—
—
—
0
0
34
428
0.78
0.69
1.8
1.7
—
—
—
0
0
371
3826
0.86
0.65
5.4
4.6
5.8
5.9
mmol/l
2.14
339
3514
8
51
1.58
0.60
1.4
1.1
—
—
—
0
0
26
202
1.30
0.58
2.2
2.3
—
—
—
0
0
340
3518
0.88
0.58
38.7
15.2
38.9
39.7
%
1.09
219
2506
5
89
0.56
0.56
1.0
1.3
—
—
—
0
0
7
106
0.66
0.49
1.3
1.1
—
—
—
0
0
7
46
1.53
0.48
1.4
1.2
—
—
—
0
0
50
431
1.18
0.47
2.3
4.2
9.2
16.9
ug/l
0.31
41
365
7
49
1.43
0.46
1.4
1.1
—
—
—
0
0
53
465
1.16
0.42
1.4
1.3
—
—
—
0
0
21
260
0.80
0.41
1.1
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
2.6
—
78.6
—
0
11
5
34
1.48
0.40
15.6
2.2
15.2
13.3
%
—
5
34
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
9
68
1.33
0.38
1.1
1.2
—
—
—
0
0
6
43
1.40
0.35
1.2
1.4
—
—
—
0
0
63
695
0.89
0.34
3.0
3.1
0.7
0.8
ug/l
0.69
46
460
18
218
0.82
0.31
2.7
2.7
59.2
60.4
u/ml
0.01
18
211
8
63
1.27
0.28
4.5
1.8
74.8
58.1
%
—
8
63
5
39
1.28
0.23
3.2
2.6
—
—
—
0
0
23
200
1.16
0.22
5.2
3.7
—
—
—
0
0
13
157
0.82
0.22
1.1
1.1
—
—
—
0
0
5
41
1.22
0.22
1.8
2.0
—
—
—
0
0
13
156
0.83
0.21
1.3
1.3
40.3
25.1
iu/l
0.95
13
132
46
500
0.91
0.21
1.5
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
0.7
—
0
7
0
14
0.00
0.20
0.0
1.0
—
0.2
—
0
5
0
14
0.00
0.20
0.0
1.1
—
0.1
—
0
6
37
340
1.10
0.17
1.4
1.4
—
—
—
0
0
13
149
0.87
0.13
1.1
1.1
—
—
—
0
0
9
107
0.84
0.13
1.1
1.3
—
—
—
0
0
5
45
1.11
0.10
3.8
2.6
3.6
5.6
umol/l
—
5
31
10
114
0.87
0.09
1.1
1.3
—
—
—
0
0
6
55
1.09
0.09
1.0
1.1
—
—
—
0
0
10
113
0.88
0.08
1.1
1.3
—
—
—
0
0
10
113
0.88
0.08
1.1
1.3
—
—
—
0
0
25
266
0.94
0.08
1.5
1.2
124.1
151.1
iu/ml
0.17
11
107
10
112
0.89
0.07
1.1
1.3
—
—
—
0
0
8
78
1.03
0.07
1.1
1.2
—
—
—
0
0
119
1170
1.02
0.05
4.1
5.1
2.2
2.5
ug/l
0.47
99
1047
14
136
1.03
0.00
1.4
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
17.3
—
0
6
0
8
0.00
0.00
0.0
1.4
—
1.6
—
0
8
0
7
0.00
0.00
0.0
1.4
—
42.7
—
0
7
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
4.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint RESP_ILL_DIS_CLASS_ELSEWHERE and mortality.

Females

Parameter HR [95% CI] p-value
RESP_ILL_DIS_CLASS_ELSEWHERE 3.745 [3.08, 4.55] < 0.001
Birth year 0.994 [0.99, 1.0] 0.194

During the follow-up period (1.1.1998 — 31.12.2019), 396 out of 1005 females with RESP_ILL_DIS_CLASS_ELSEWHERE died.

Males

Parameter HR [95% CI] p-value
RESP_ILL_DIS_CLASS_ELSEWHERE 3.158 [2.5, 3.98] < 0.001
Birth year 0.988 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 342 out of 764 males with RESP_ILL_DIS_CLASS_ELSEWHERE died.

Mortality risk

Mortality risk for people of age

years, who have RESP_ILL_DIS_CLASS_ELSEWHERE.

N-year risk Females Males
1 0.345% 0.573%
5 2.154% 3.715%
10 5.214% 8.745%
15 9.821% 16.302%
20 17.124% 26.876%

Relationships between endpoints

Index endpoint: RESP_ILL_DIS_CLASS_ELSEWHERE – Respiratory disorders in diseases classified elsewhere

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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