No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
203 |
4. Check minimum number of eventsNone |
203 |
5. Include endpointsNone |
203 |
6. Filter based on genotype QC (FinnGen only) |
203 |
Control definitions (FinnGen only)
- Control exclude
- RHEUMA_CHRYSTAL
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to Other/unspecified crystal arthropathies based on the number of shared cases.
Similar with more cases:
- Other crystal arthropathies
- Crystal arthropathies, rheuma endpoint
- Polyarthropathies
- Finngen Rheumatological endpoints
- Arthropathies
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 1547 | 864 | 670 |
Only index persons | 1294 | 716 | 578 |
Unadjusted period prevalence (%) | |||
Whole population | 0.02 | 0.02 | 0.02 |
Only index persons | 0.02 | 0.03 | 0.02 |
Median age at first event (years) | |||
Whole population | 73.60 | 75.80 | 70.78 |
Only index persons | 72.74 | 74.85 | 70.12 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 203 | 104 | 99 |
Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
Median age at first event (years) | 69.74 | 68.37 | 71.17 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 178
- Matched controls
- 1778
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint CHRYSTAL_NOS and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
CHRYSTAL_NOS | 1.612 [1.3, 2.0] | < 0.001 |
Birth year | 0.991 [0.98, 1.0] | 0.049 |
During the follow-up period (1.1.1998 — 31.12.2019), 301 out of 641 females with CHRYSTAL_NOS died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
CHRYSTAL_NOS | 1.755 [1.31, 2.36] | < 0.001 |
Birth year | 0.982 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 218 out of 482 males with CHRYSTAL_NOS died.
Mortality risk
Mortality risk for people of age
years, who have CHRYSTAL_NOS.N-year risk | Females | Males |
---|---|---|
1 | 0.143% | 0.325% |
5 | 0.84% | 1.923% |
10 | 2.169% | 4.736% |
15 | 4.007% | 8.626% |
20 | 7.146% | 14.061% |
Relationships between endpoints
↥Index endpoint: CHRYSTAL_NOS – Other/unspecified crystal arthropathies
GWS hits: -