Benign neoplasm of male genital organs

CD2_BENIGN_MALE_GEN

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only males

226754

2. Check conditions

None

226754

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D29
  • Cause of death: ICD-10 D29

2 out of 7 registries used, show all original rules.

641

4. Check minimum number of events

None

641

5. Include endpoints

769

6. Filter based on genotype QC (FinnGen only)

748

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
D10-D36
Name in latin
Neoplasmata benigna organorum genitalium masculinorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5564 - 5564
Only index persons 4801 - 4801
Unadjusted period prevalence (%)
Whole population 0.16 - 0.16
Only index persons 0.18 - 0.18
Median age at first event (years)
Whole population - - 52.91
Only index persons - - 50.02

-FinnGen-

Key figures

All Female Male
Number of individuals 748 - 748
Unadjusted period prevalence (%) 0.34 - 0.34
Median age at first event (years) 58.88 - 58.88

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
769
Matched controls
7690
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D29.1
ICD-10 Finland
Benign neoplasm: Prostate
501.2
253.8
240
7
D29.2
ICD-10 Finland
Benign neoplasm: Testis
1417.9
126.8
120
*
D29.3
ICD-10 Finland
Benign neoplasm: Epididymis
+∞
112.3
105
*
D29.4
ICD-10 Finland
Benign neoplasm: Scrotum
258.9
110.9
111
5
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
33.3
103.2
67
22
KFC00
NOMESCO Finland
Unilateral orchiectomy
16.9
71.6
61
39
D29.0
ICD-10 Finland
Benign neoplasm: Penis
+∞
53.8
51
*
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
6.2
46.3
84
149
22200
ICD-8 Finland
Benign neoplasm of male genital organs, Testis
+∞
27.2
26
*
22288
ICD-8 Finland
Benign neoplasm of male genital organs, Loco alio definito
+∞
26.2
25
*
KFD16
NOMESCO Finland
Partial excision of epididymis
31.3
25.2
33
11
KFA00
NOMESCO Finland
Exploration of testis
26.8
19.2
26
10
2223A
ICD-9 Finland
Benign neoplasm of male genital organs, Epididymis
+∞
18.8
18
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.0
18.1
53
140
D29.9
ICD-10 Finland
Benign neoplasm: Male genital organ, unspecified
+∞
17.8
17
*
2220A
ICD-9 Finland
Benign neoplasm of male genital organs, Testis
+∞
16.7
16
*
22210
ICD-8 Finland
Benign neoplasm of male genital organs, Penis
+∞
14.6
14
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
2.1
14.6
172
937
Y05
ICPC
Scrotum/testis sympt/compl other
5.2
14.2
29
57
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
2.1
14.0
147
766
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
2.1
13.7
161
876
9061/3-C62.9
ICD-O-3
Seminoma, NOS, of testis, NOS
76.5
13.6
15
*
ZXC96
NOMESCO Finland
Robot assisted procedure
3.6
13.4
45
131
N40
ICD-10 Finland
Hyperplasia of prostate
1.8
13.2
346
2429
KGB00
NOMESCO Finland
Biopsy of penis
23.0
12.9
18
8
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
3.3
12.8
48
150
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.9
12.6
196
1171
D29.7
ICD-10 Finland
Benign neoplasm: Other male genital organs
+∞
12.5
12
*
22280
ICD-8 Finland
Benign neoplasm of male genital organs, Scroti
+∞
12.5
12
*
XKD00
NOMESCO Finland
Uroflowmetry
1.8
12.5
230
1450
UKC02
NOMESCO Finland
Cystoscopy
1.9
12.1
192
1153
N43.4
ICD-10 Finland
Spermatocele
3.6
12.0
39
111
C62.11
ICD-10 Finland
Malignant tumor of the descending testicle, seminoma
47.4
11.9
14
*
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
3.4
11.7
42
128
XJH00
NOMESCO Finland
Transanal ultrasonography
2.2
11.0
97
469
NK6AN
NOMESCO Finland
Total body bone isotope imaging
3.5
11.0
37
108
J01DB01
ATC
cefalexin; oral
1.8
10.6
600
5081
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
9.8
139
800
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
9.1
83
407
7511
FHL
Orchidectomy (unilateral), also includes funicularectomy
12.9
8.4
14
11
22299
ICD-8 Finland
Benign neoplasm of male genital organs, Unspecified site
+∞
8.3
8
*
J01MA02
ATC
ciprofloxacin; systemic
1.6
8.2
314
2350
D40.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other male genital organs
22.3
8.0
11
5
M02AA10
ATC
ketoprofen; topical
1.9
7.9
107
605
G04CA02
ATC
tamsulosin; oral
1.5
7.9
339
2598
7501
FHL
Testicular exploration (includes removal of biopsy, detorsion or appendix test)
12.0
7.6
13
11
KFW96
NOMESCO Finland
Other operation on scrotum or scrotal organs
25.3
7.6
10
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
7.5
195
1325
KFD96
NOMESCO Finland
Other excision or ligature of scrotal organs
80.8
7.4
8
*
C05AA08
ATC
fluocortolone; rectal, topical
1.9
7.1
98
558
N50.8
ICD-10 Finland
Other specified disorders of male genital organs
4.3
6.8
17
40
KFH50
NOMESCO Finland
Insertion of prosthetic replacement for testis
40.4
6.8
8
*
KFD70
NOMESCO Finland
Excision of lesion of skin of scrotum
40.4
6.8
8
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
6.6
204
1441
L03
ICPC
Low back symptom/complaint
1.6
6.2
153
1023
KFD30
NOMESCO Finland
Operation for spermatocele
4.0
6.2
17
43
S18
ICPC
Laceration/cut
1.5
6.2
330
2606
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
3.7
6.1
19
53

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
42
24
18.45
51.85
3.9
2.4
31.73
63.84
u/l
—
6
5
294
2090
1.66
9.96
2.2
2.2
—
—
—
0
0
538
4510
1.64
8.86
6.3
5.1
2.65
2.95
ug/l
0.24
473
4027
451
3716
1.52
7.23
5.1
4.2
142.89
1301.57
e6/l
—
9
68
469
3936
1.49
6.59
5.0
4.1
—
—
—
0
0
396
3228
1.47
6.35
17.1
18.8
1.32
1.38
inr
0.48
122
917
12
15
8.11
5.85
1.8
4.6
—
—
—
0
0
387
3172
1.44
5.85
6.7
7.2
11.87
13.17
umol/l
1.99
376
3026
137
913
1.61
5.60
2.6
2.3
12.15
13.48
nmol/l
1.10
116
817
98
601
1.72
5.51
5.8
4.9
—
—
—
0
0
524
4573
1.46
5.47
8.6
8.3
77.49
80.31
u/l
0.75
493
4319
555
4900
1.48
5.44
3.8
3.8
1.91
2.04
mu/l
1.35
487
4407
38
173
2.26
5.05
1.6
1.4
6.13
5.92
u/l
0.05
28
140
242
1862
1.44
4.95
4.9
4.2
—
—
—
0
0
635
5803
1.54
4.90
17.8
17.0
28.07
29.88
mg/l
0.58
528
4725
68
392
1.81
4.73
2.5
3.4
4.22
6.72
e9/l
0.90
47
315
113
748
1.60
4.73
1.2
1.4
—
—
—
0
0
436
3752
1.37
4.47
5.1
5.7
6.68
6.92
mmol/l
1.86
415
3569
333
2747
1.37
4.43
7.1
7.3
1.20
1.20
mmol/l
0.55
295
2514
359
3001
1.37
4.38
7.9
8.1
1.20
1.20
mmol/l
0.20
291
2552
334
2765
1.37
4.32
2.7
2.9
—
—
—
0
0
476
4176
1.37
4.19
4.2
3.9
12.41
12.84
mm/h
0.21
434
3841
238
1872
1.39
4.19
2.3
2.2
289.34
294.19
u/l
0.02
223
1755
651
6038
1.51
4.09
21.2
20.2
139.69
139.62
mmol/l
0.27
631
5892
653
6061
1.51
4.09
21.3
20.4
4.02
4.04
mmol/l
1.00
633
5912
330
2748
1.35
4.03
6.1
6.6
9.02
9.16
%
0.28
303
2592
335
2803
1.35
3.94
6.0
6.4
25.16
25.80
%
0.47
309
2648
329
2750
1.34
3.87
5.5
6.2
59.29
58.59
%
0.48
298
2603
327
2732
1.34
3.86
5.8
6.3
2.71
2.93
%
1.15
300
2575
353
2993
1.33
3.73
5.5
6.3
0.19
0.21
e9/l
1.19
308
2631
239
1917
1.36
3.65
3.3
2.9
57.79
101.12
u/l
0.53
225
1795
79
514
1.60
3.57
1.2
1.4
—
—
—
0
0
317
2664
1.32
3.50
5.9
6.2
0.63
0.63
%
0.01
289
2518
246
2000
1.34
3.40
4.0
3.5
44.11
116.01
e6/l
1.29
200
1605
340
2902
1.31
3.30
5.3
6.0
0.62
0.63
e9/l
0.51
294
2500
340
2906
1.30
3.26
5.4
6.0
0.04
0.04
e9/l
0.49
294
2516
238
1937
1.33
3.24
3.1
3.7
36.26
37.90
u/l
0.19
223
1842
383
3332
1.30
3.19
8.9
9.5
4.47
4.38
e9/l
0.24
343
2909
680
6433
1.49
3.17
26.4
24.2
229.56
230.48
e9/l
0.14
661
6249
680
6433
1.49
3.17
26.5
24.5
40.99
41.67
%
0.41
632
5955
264
2190
1.31
3.12
2.8
2.8
181.28
201.37
ug/l
0.62
237
1998
345
2968
1.29
3.10
5.4
6.2
1.71
1.95
e9/l
1.56
303
2619
680
6438
1.49
3.10
26.3
24.0
30.50
30.61
pg
0.89
668
6325
680
6438
1.49
3.10
26.3
24.1
91.21
91.45
fl
0.69
667
6326
680
6439
1.48
3.09
26.4
24.1
4.57
4.57
e12/l
0.04
656
6236
680
6439
1.48
3.09
26.4
24.2
6.99
6.96
e9/l
0.10
658
6239
680
6440
1.48
3.08
26.6
24.3
138.39
139.09
g/l
0.49
668
6324
296
2499
1.30
3.06
2.0
2.1
92.65
91.91
pmol/l
0.08
161
1415
41
234
1.79
3.02
1.5
1.6
—
—
—
0
0
321
2745
1.29
2.99
6.5
6.6
—
—
—
0
0
60
384
1.61
2.93
3.0
2.8
—
—
—
0
0
639
5999
1.39
2.90
18.6
16.1
—
—
—
0
0
211
1715
1.32
2.85
3.8
3.4
—
—
—
0
0
176
1404
1.33
2.70
3.1
2.7
2.65
2.99
e6/l
0.40
160
1261
51
322
1.63
2.65
5.1
4.1
23.98
24.92
mmol/l
1.76
44
300
234
1954
1.28
2.55
2.7
2.8
—
—
—
0
0
239
2012
1.27
2.43
2.2
2.2
75.75
74.78
nmol/l
0.21
201
1774
29
161
1.83
2.38
4.9
5.2
2.98
2.21
mmol/l
0.50
20
105
49
317
1.58
2.33
1.8
1.8
37.97
39.17
nmol/l
0.13
49
305
257
2192
1.26
2.32
4.6
3.9
58.31
139.42
e6/l
1.28
201
1685
100
749
1.39
2.30
1.5
1.3
—
—
—
0
0
416
3752
1.24
2.25
3.0
3.1
15.03
14.95
pmol/l
0.24
367
3347
215
1802
1.27
2.24
3.9
3.4
0.55
0.52
e6/l
0.03
169
1423
430
3894
1.24
2.23
3.5
3.4
55.56
60.23
u/l
0.54
397
3624
609
5742
1.29
2.19
4.6
4.6
4.32
4.36
mmol/l
0.49
544
5282
650
6185
1.33
2.16
11.9
11.0
28.49
29.65
u/l
0.65
620
5969
292
2546
1.24
2.14
4.3
4.0
42.14
57.99
ng/l
0.93
225
1940
11
44
2.52
2.02
4.4
4.4
7.43
7.43
ph
—
5
14
176
1459
1.27
2.00
3.1
3.1
—
—
—
0
0
16
77
2.10
1.97
1.7
1.4
113.16
172.24
pmol/l
1.59
16
77
180
1499
1.26
1.96
2.6
2.7
—
—
—
0
0
236
2032
1.23
1.91
3.2
3.3
2047.40
1933.23
ng/l
0.11
197
1770
49
334
1.50
1.89
1.9
2.1
1.23
1.38
ug/l
0.11
37
296
239
2065
1.23
1.87
4.3
4.7
—
—
—
0
0
151
1239
1.27
1.86
1.8
1.8
1139.80
1164.58
nmol/l
0.09
106
954
83
626
1.37
1.86
1.6
1.6
—
—
—
0
0
102
798
1.32
1.80
1.9
1.8
—
—
—
0
0
594
5628
1.24
1.77
5.2
4.8
6.03
6.15
mmol/l
1.46
523
5075
585
5538
1.24
1.73
4.2
4.1
1.32
1.35
mmol/l
0.37
517
5033
600
5696
1.24
1.73
4.8
4.6
1.32
1.29
mmol/l
0.85
538
5198
25
148
1.71
1.72
1.4
1.6
—
—
—
0
0
615
5857
1.25
1.71
5.0
5.1
2.57
2.60
mmol/l
0.37
550
5344
27
164
1.67
1.70
3.8
4.1
—
—
—
0
0
295
2624
1.20
1.69
3.6
3.1
0.67
0.77
ug/l
1.78
213
1754
187
1590
1.23
1.69
2.2
2.1
2.97
3.02
mg/l
0.12
159
1357
8
32
2.52
1.60
18.9
12.4
—
—
—
0
0
113
913
1.28
1.59
2.8
2.9
21.96
23.93
%
0.88
97
788
44
306
1.46
1.58
2.6
2.4
—
—
—
0
0
36
242
1.51
1.52
2.0
2.9
9.74
11.15
g/l
1.02
28
216
118
966
1.26
1.50
2.6
2.8
2.13
2.21
g/l
0.87
105
902
16
87
1.86
1.46
7.2
5.2
—
—
—
0
0
104
843
1.27
1.43
2.5
2.6
1.67
1.77
%
0.65
93
762
40
279
1.46
1.43
1.2
1.2
—
—
—
0
0
61
459
1.36
1.43
3.4
2.7
—
—
—
0
0
81
637
1.30
1.41
1.8
1.8
—
—
—
0
0
298
2695
1.17
1.35
5.2
5.8
34.80
34.92
g/l
0.12
270
2510
90
1109
0.79
1.35
4.0
3.4
2.45
2.45
mmol/l
0.32
81
981
54
403
1.37
1.34
1.4
1.6
—
—
—
0
0
34
233
1.48
1.34
1.9
1.7
—
—
—
0
0
73
571
1.31
1.33
3.1
2.8
65.97
65.89
g/l
0.03
61
526
162
1393
1.21
1.31
6.7
6.9
—
—
—
0
0
129
1085
1.23
1.30
3.6
3.2
1.23
0.58
e6/l
0.74
78
669
39
277
1.43
1.29
2.4
2.5
201.85
609.41
ug/l
1.40
34
269
80
637
1.29
1.29
2.3
2.7
68.67
68.11
e9/l
0.06
63
507
15
84
1.80
1.27
2.3
2.5
1.86
2.31
g/24h
—
8
39
48
355
1.38
1.27
1.3
1.9
1.73
1.52
g/l
0.77
39
313
9
44
2.06
1.27
2.9
2.6
—
—
—
0
0
133
1126
1.22
1.26
3.3
3.0
1.10
0.90
e6/l
0.27
79
707
5
117
0.42
1.25
1.2
1.4
—
—
—
0
0
6
25
2.41
1.24
2.7
1.2
0.15
0.17
nmol/l
—
6
16
148
1268
1.21
1.24
3.9
3.9
205.45
463.16
ng/l
1.25
128
1070
197
1733
1.18
1.24
5.4
4.6
7.39
7.40
ph
0.57
49
333
15
85
1.78
1.23
2.7
2.6
—
—
—
0
0
123
1037
1.22
1.22
2.7
2.8
12.07
12.98
umol/l
0.74
112
973
30
205
1.48
1.21
1.3
2.8
38.16
37.07
g/l
0.36
23
179
157
1359
1.20
1.18
3.3
3.0
578.26
584.83
mosm/kgh2o
0.15
138
1162
79
636
1.27
1.18
1.4
1.4
—
—
—
0
0
13
72
1.82
1.15
1.2
1.1
—
—
—
0
0
13
72
1.82
1.15
6.2
4.6
54.81
55.73
%
—
8
67
50
382
1.33
1.10
4.9
3.8
—
—
—
0
0
14
81
1.74
1.09
1.2
2.3
—
—
—
0
0
199
1770
1.17
1.09
3.2
3.0
4704.64
6770.64
umol/l
0.27
177
1544
7
33
2.13
1.05
1.4
1.1
—
—
—
0
0
178
2002
0.86
1.05
3.0
2.9
—
—
—
0
0
510
4857
1.15
1.05
19.8
20.0
15.76
15.18
%
1.02
501
4768
8
150
0.53
1.04
3.3
3.0
—
—
—
0
0
60
477
1.28
1.01
4.0
4.7
0.04
0.13
%
0.96
23
187
69
559
1.26
1.00
3.0
2.6
34.81
41.64
u/l
0.38
62
487
25
173
1.46
0.98
3.3
3.3
—
—
—
0
0
5
23
2.18
0.98
1.4
1.1
—
—
—
0
0
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
293
2702
1.14
0.96
5.1
4.6
0.00
0.00
estimate
-0.00
62
532
65
528
1.25
0.93
4.8
3.7
4.99
5.15
kpa
0.84
59
504
171
1522
1.16
0.93
1.5
1.6
18.65
19.08
nmol/l
0.14
141
1300
86
721
1.22
0.93
2.8
3.2
8.97
10.83
umol/l
0.26
75
653
76
629
1.23
0.93
3.1
2.5
0.21
0.21
g/l
0.03
70
576
64
520
1.25
0.92
4.9
3.7
7.41
7.40
ph
—
6
59
296
2741
1.13
0.90
4.0
3.5
0.00
0.00
estimate
-0.00
58
495
52
416
1.27
0.86
4.8
5.1
108.08
112.96
ng/l
0.10
46
366
8
44
1.83
0.86
4.1
3.1
—
—
—
0
0
31
231
1.36
0.84
1.1
1.2
—
—
—
0
0
18
121
1.50
0.83
3.4
3.3
62.89
56.58
%
1.15
18
121
22
155
1.43
0.82
2.6
2.9
—
—
—
0
0
56
457
1.24
0.80
3.8
4.3
0.95
0.58
%
0.41
21
191
74
623
1.21
0.79
7.8
10.3
—
—
—
0
0
45
360
1.27
0.76
1.9
1.8
1.07
1.57
g/l
0.81
38
337
61
506
1.22
0.76
4.0
4.6
0.92
0.91
%
0.00
24
217
66
552
1.21
0.76
3.8
3.4
—
—
—
0
0
54
442
1.24
0.75
4.1
4.8
0.06
0.12
%
0.31
17
154
12
75
1.61
0.75
1.3
1.2
—
—
—
0
0
17
116
1.48
0.74
3.2
3.1
5.11
4.42
e9/l
0.36
17
116
123
1088
1.16
0.74
4.1
3.7
0.80
0.82
mmol/l
1.04
114
1027
5
24
2.09
0.74
1.4
1.7
—
—
—
0
0
79
674
1.19
0.74
3.2
4.3
—
7.37
—
0
5
562
5441
1.12
0.72
6.8
6.3
40.55
40.84
mmol/mol
0.31
494
5019
7
39
1.80
0.72
1.7
1.5
—
—
—
0
0
35
273
1.30
0.72
1.2
1.2
—
—
—
0
0
77
658
1.19
0.71
3.2
4.3
2.26
1.82
mmol/l
0.54
63
539
5
26
1.93
0.70
1.8
1.3
—
—
—
0
0
92
800
1.17
0.70
1.8
1.8
—
—
—
0
0
292
2737
1.11
0.69
4.0
3.5
0.00
0.00
estimate
0.50
62
557
163
1479
1.13
0.69
3.8
3.2
—
—
—
0
0
10
61
1.65
0.68
1.0
1.2
—
—
—
0
0
5
28
1.79
0.66
1.6
1.9
435.40
1779.11
u/ml
—
5
28
6
103
0.58
0.62
1.0
1.3
—
—
—
0
0
235
2190
1.11
0.62
3.8
3.2
5.83
5.74
ph
0.13
12
146
8
49
1.64
0.62
1.1
1.1
—
—
—
0
0
75
651
1.17
0.60
1.3
1.3
248.00
367.80
titre
—
10
118
148
1348
1.12
0.59
1.7
1.7
110924805.26
18878415.65
pmol/l
0.61
119
1123
51
428
1.21
0.59
1.5
1.5
—
—
—
0
0
36
291
1.25
0.59
3.2
3.9
—
—
—
0
0
18
132
1.37
0.57
2.6
2.3
—
—
—
0
0
16
115
1.40
0.57
1.1
1.3
—
—
—
0
0
20
150
1.34
0.56
2.0
1.5
—
—
—
0
0
18
133
1.36
0.55
1.5
1.7
—
—
—
0
0
21
161
1.31
0.52
1.2
1.3
1.07
1.15
g/l
1.02
21
155
29
233
1.25
0.51
2.1
1.7
—
—
—
0
0
18
135
1.34
0.51
3.7
1.9
0.91
0.83
nmol/l
0.28
13
118
35
289
1.22
0.49
1.0
1.2
—
—
—
0
0
7
46
1.53
0.48
2.1
1.5
—
—
—
0
0
14
102
1.38
0.47
1.2
1.2
—
—
—
0
0
52
599
0.86
0.46
1.5
1.4
—
—
—
0
0
29
350
0.82
0.44
1.2
1.4
—
—
—
0
0
20
157
1.28
0.43
1.2
1.3
0.22
0.24
g/l
0.80
20
150
53
463
1.16
0.42
3.1
2.6
10.48
11.36
g/l
0.78
45
423
12
161
0.74
0.41
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
1.16
—
0
15
8
59
1.36
0.41
1.1
1.2
—
—
—
0
0
30
250
1.21
0.41
4.0
3.8
0.32
0.26
g/l
0.25
23
120
7
102
0.68
0.39
1.1
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
7.2
—
—
—
0
0
19
151
1.26
0.39
3.4
3.8
37.80
29.68
mg/l
0.18
11
103
5
36
1.39
0.38
4.0
4.2
844.80
89.11
nmol/l
—
5
36
142
1518
0.92
0.37
1.7
1.7
1.39
1.43
mmol/l
0.22
123
1247
164
1542
1.08
0.37
4.5
3.7
0.00
0.01
estimate
0.69
60
488
9
71
1.27
0.36
1.0
1.2
—
—
—
0
0
6
42
1.43
0.35
1.0
1.6
—
—
—
0
0
21
172
1.23
0.34
3.4
4.7
—
—
—
0
0
6
44
1.37
0.34
2.2
2.2
24.67
16.73
%
—
6
44
17
210
0.81
0.33
2.9
2.3
101.22
113.86
ug/min
—
9
123
22
264
0.83
0.33
4.1
4.0
402.65
4994.43
u/ml
0.62
17
218
80
733
1.10
0.33
1.2
1.2
51.71
37.26
iu/ml
0.20
23
206
33
285
1.16
0.32
1.7
1.3
—
10.68
—
0
10
6
47
1.28
0.32
1.2
1.3
—
—
—
0
0
14
176
0.79
0.32
1.4
1.2
—
—
—
0
0
12
154
0.78
0.32
1.4
1.6
188.59
264.37
ug/g
—
7
98
102
948
1.09
0.31
7.9
7.2
1.05
1.01
mmol/l
0.76
94
889
30
258
1.17
0.31
1.1
1.3
990.39
258.49
u/ml
0.48
25
231
7
98
0.71
0.31
1.0
1.5
—
—
—
0
0
7
53
1.32
0.31
1.0
1.2
—
—
—
0
0
19
157
1.22
0.29
2.5
1.9
14.24
12.16
mg/l
0.45
19
145
56
616
0.90
0.28
2.6
3.0
296.18
234.48
ng/l
0.30
50
560
51
563
0.90
0.28
1.4
1.4
—
—
—
0
0
56
510
1.11
0.27
1.7
2.3
384.66
365.01
nmol/l
0.35
50
462
42
467
0.89
0.26
1.3
1.4
—
—
—
0
0
47
519
0.90
0.26
3.9
5.7
—
—
—
0
0
10
77
1.30
0.26
5.3
3.7
—
—
—
0
0
20
169
1.19
0.26
4.6
2.5
—
—
—
0
0
73
676
1.09
0.25
1.3
1.2
2.49
13.15
u/ml
2.72
24
256
13
105
1.24
0.25
2.5
2.6
—
—
—
0
0
133
1263
1.06
0.24
3.8
3.5
—
—
—
0
0
12
148
0.81
0.24
1.8
2.4
121.67
130.26
g/l
—
6
114
125
1186
1.06
0.24
1.6
1.7
1.27
1.51
mg/l
0.51
98
929
14
169
0.83
0.24
3.5
9.8
104.64
105.56
mmol/l
0.45
14
151
14
169
0.83
0.24
3.5
9.8
10.93
11.72
mmol/l
0.45
14
151
262
2539
1.05
0.24
10.4
10.4
0.00
0.00
e9/l
0.59
215
2082
5
39
1.28
0.23
1.2
1.6
1.13
1.01
g/l
—
5
39
19
163
1.17
0.21
1.1
1.2
—
1.52
—
0
13
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
96.20
—
0
10
0
12
0.00
0.21
0.0
3.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
8.05
—
0
7
8
103
0.77
0.21
1.6
2.3
—
—
—
0
0
40
364
1.10
0.21
2.5
2.8
—
—
—
0
0
37
407
0.90
0.20
10.6
13.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
6.5
—
—
—
0
0
0
14
0.00
0.20
0.0
3.1
—
—
—
0
0
0
14
0.00
0.20
0.0
8.1
—
—
—
0
0
6
50
1.20
0.19
2.2
1.6
81.67
90.30
umol/l
—
6
50
161
1550
1.05
0.19
1.3
1.3
—
—
—
0
0
54
501
1.08
0.19
5.1
3.6
—
—
—
0
0
18
207
0.87
0.19
1.2
1.1
27.61
155.29
iu/ml
—
9
70
14
118
1.19
0.19
1.4
1.2
—
—
—
0
0
6
52
1.16
0.19
1.0
1.3
—
—
—
0
0
77
726
1.07
0.19
1.5
1.5
—
—
—
0
0
12
143
0.84
0.18
1.2
1.4
—
—
—
0
0
7
58
1.21
0.18
3.6
2.0
33.37
36.90
%
—
7
58
7
60
1.17
0.18
1.6
1.3
—
—
nmol/l
—
0
0
22
195
1.13
0.17
5.5
3.4
—
—
—
0
0
11
131
0.84
0.17
11.8
3.5
—
—
—
0
0
201
2068
0.96
0.17
4.6
4.0
12.45
11.24
mg/mmol
0.09
134
1436
75
711
1.06
0.16
7.5
8.7
10.87
10.95
mmol/l
0.03
69
677
190
1954
0.96
0.15
3.8
3.5
61.23
281.02
mg/l
2.24
128
1383
7
87
0.80
0.14
1.9
3.0
—
—
—
0
0
20
179
1.12
0.14
4.7
2.2
—
—
—
0
0
12
103
1.17
0.14
1.2
1.1
—
—
—
0
0
20
181
1.11
0.12
4.6
2.5
—
—
—
0
0
12
137
0.87
0.12
1.3
1.4
—
—
—
0
0
202
2062
0.97
0.11
3.9
3.4
8.02
8.48
mmol/l
0.79
162
1728
37
348
1.07
0.10
2.7
3.8
25.06
25.01
mmol/l
0.03
37
335
89
920
0.96
0.10
1.8
1.4
2.44
2.83
g/l
1.48
57
592
20
183
1.10
0.10
4.6
2.4
—
—
—
0
0
20
183
1.10
0.10
4.6
2.5
—
—
—
0
0
5
44
1.14
0.10
3.6
1.2
182.80
146.63
nmol/l
—
5
44
5
44
1.14
0.10
5.0
3.3
—
—
—
0
0
12
135
0.89
0.10
1.5
1.4
—
—
—
0
0
28
299
0.93
0.09
6.7
4.7
—
—
—
0
0
6
54
1.11
0.09
3.0
1.5
10.07
11.58
%
—
6
54
15
136
1.10
0.08
1.2
1.1
—
—
—
0
0
5
62
0.81
0.08
1.4
1.3
—
—
—
0
0
6
71
0.84
0.07
11.0
3.8
—
—
—
0
0
7
81
0.86
0.07
1.0
1.2
—
—
—
0
0
7
84
0.83
0.07
1.4
1.4
—
—
—
0
0
88
858
1.03
0.07
7.1
9.1
5.02
5.10
kpa
0.34
81
824
88
859
1.03
0.06
7.1
9.1
11.67
11.92
kpa
0.18
83
827
419
4219
0.98
0.06
3.9
4.2
—
—
—
0
0
21
223
0.94
0.06
1.1
1.1
—
—
—
0
0
94
960
0.98
0.06
1.3
1.2
1.96
1.27
u/ml
0.31
24
259
12
131
0.91
0.05
1.7
2.5
—
—
—
0
0
102
1001
1.02
0.05
1.9
2.2
—
—
—
0
0
27
283
0.95
0.05
1.6
1.4
—
—
—
0
0
87
857
1.02
0.03
7.3
9.2
1.17
0.99
mmol/l
0.17
74
669
20
192
1.04
0.02
16.6
12.6
—
—
—
0
0
53
537
0.99
0.01
2.7
2.7
158.87
163.91
ug/g
0.05
42
453
192
1912
1.01
0.01
3.8
3.6
2.35
2.33
mmol/l
0.81
161
1686
11
104
1.06
0.01
1.1
1.1
—
—
—
0
0
10
106
0.94
0.01
3.5
1.4
—
—
—
0
0
125
1257
0.99
0.00
4.8
3.8
1.02
1.02
kg/l
0.02
20
178
12
126
0.95
0.00
1.2
1.5
25.94
31.35
g/l
0.72
12
112
15
144
1.04
0.00
3.9
2.6
—
—
—
0
0
16
154
1.04
0.00
1.2
1.2
—
—
—
0
0
34
334
1.02
0.00
1.5
1.2
—
—
—
0
0
11
115
0.96
0.00
1.2
1.4
1550.18
1806.04
e6/l
0.12
11
84
13
132
0.98
0.00
1.2
1.0
—
—
—
0
0
22
222
0.99
0.00
1.4
2.1
20.88
22.45
s
0.69
16
205
67
667
1.00
0.00
3.9
4.4
4.30
34.23
ug/l
1.61
58
561
10
101
0.99
0.00
1.2
1.1
—
3.64
—
0
8
66
662
1.00
0.00
1.9
2.5
7.50
8.58
ug/l
0.29
52
593
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
3.0
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.06
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.2
1.4
—
—
—
0
0
9
90
1.00
-0.00
1.3
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
74
0.95
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
74
0.95
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
2.37
—
0
9
6
60
1.00
-0.00
1.5
1.2
—
—
—
0
0
5
49
1.02
-0.00
12.8
3.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
61
0.98
-0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
384.83
—
0
6
6
65
0.92
-0.00
1.0
1.2
1.76
1.47
nmol/l
—
6
58
5
54
0.93
-0.00
1.4
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
10
100
1.00
-0.00
3.8
3.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
17.03
—
0
7
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.5
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
1.10
—
0
5
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MALE_GEN and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MALE_GEN 1.301 [1.15, 1.47] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 965 out of 3809 males with CD2_BENIGN_MALE_GEN died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MALE_GEN.

N-year risk Females Males
1 No data 0.238%
5 No data 1.447%
10 No data 3.479%
15 No data 6.681%
20 No data 11.102%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MALE_GEN – Benign neoplasm of male genital organs

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data