Benign neoplasm of male genital organs

CD2_BENIGN_MALE_GEN

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only males

226837

2. Check conditions

None

226837

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D29
  • Cause of death: ICD-10 D29

2 out of 7 registries used, show all original rules.

609

4. Check minimum number of events

None

609

5. Include endpoints

737

6. Filter based on genotype QC (FinnGen only)

737

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
D10-D36
Name in latin
Neoplasmata benigna organorum genitalium masculinorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5564 - 5564
Only index persons 4801 - 4801
Unadjusted period prevalence (%)
Whole population 0.16 - 0.16
Only index persons 0.18 - 0.18
Median age at first event (years)
Whole population - - 52.91
Only index persons - - 50.02

-FinnGen-

Key figures

All Female Male
Number of individuals 737 - 737
Unadjusted period prevalence (%) 0.32 - 0.32
Median age at first event (years) 58.18 - 58.18

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
673
Matched controls
6730
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D29.1
ICD-10 Finland
Benign neoplasm: Prostate
490.3
215.3
204
6
D29.2
ICD-10 Finland
Benign neoplasm: Testis
+∞
110.5
103
*
D29.4
ICD-10 Finland
Benign neoplasm: Scrotum
1183.9
106.3
101
*
D29.3
ICD-10 Finland
Benign neoplasm: Epididymis
982.0
89.9
86
*
D29.0
ICD-10 Finland
Benign neoplasm: Penis
+∞
50.7
48
*
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
28.9
41.4
56
21
KFC00
NOMESCO Finland
Unilateral orchiectomy
21.6
36.7
54
27
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
7.6
29.1
70
101
KFD16
NOMESCO Finland
Partial excision of epididymis
44.7
24.8
30
7
22200
ICD-8 Finland
Benign neoplasm of male genital organs, Testis
+∞
24.1
23
*
22288
ICD-8 Finland
Benign neoplasm of male genital organs, Loco alio definito
+∞
24.1
23
*
KFA00
NOMESCO Finland
Exploration of testis
26.4
17.0
23
9
2223A
ICD-9 Finland
Benign neoplasm of male genital organs, Epididymis
+∞
16.7
16
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
2.4
15.4
155
758
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.5
14.7
53
126
22210
ICD-8 Finland
Benign neoplasm of male genital organs, Penis
+∞
14.6
14
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
2.3
13.8
145
721
2220A
ICD-9 Finland
Benign neoplasm of male genital organs, Testis
+∞
13.6
13
*
KGB00
NOMESCO Finland
Biopsy of penis
29.0
13.0
17
6
22280
ICD-8 Finland
Benign neoplasm of male genital organs, Scroti
+∞
12.5
12
*
D29.9
ICD-10 Finland
Benign neoplasm: Male genital organ, unspecified
+∞
12.5
12
*
N40
ICD-10 Finland
Hyperplasia of prostate
1.8
11.8
285
1941
9061/3-C62.9
ICD-O-3
Seminoma, NOS, of testis, NOS
30.6
11.7
15
5
D29.7
ICD-10 Finland
Benign neoplasm: Other male genital organs
+∞
11.5
11
*
XKD00
NOMESCO Finland
Uroflowmetry
1.9
11.1
199
1221
J01DB01
ATC
cefalexin; oral
1.8
10.6
514
4290
UKC02
NOMESCO Finland
Cystoscopy
1.9
10.4
170
1003
ZXC96
NOMESCO Finland
Robot assisted procedure
3.8
10.1
42
116
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.9
9.9
160
939
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
3.5
9.3
43
130
C62.11
ICD-10 Finland
Malignant tumor of the descending testicle, seminoma
15.8
9.1
14
9
7501
FHL
Testicular exploration (includes removal of biopsy, detorsion or appendix test)
37.2
9.0
11
*
J01MA02
ATC
ciprofloxacin; systemic
1.7
9.0
275
1966
7511
FHL
Orchidectomy (unilateral), also includes funicularectomy
18.9
9.0
13
7
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
2.0
8.9
113
603
NK6AN
NOMESCO Finland
Total body bone isotope imaging
3.7
8.7
37
105
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
8.1
80
382
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
7.7
295
2214
D40.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other male genital organs
25.3
7.6
10
*
G04CA02
ATC
tamsulosin; oral
1.6
7.5
271
1998
22299
ICD-8 Finland
Benign neoplasm of male genital organs, Unspecified site
+∞
7.3
7
*
Y05
ICPC
Scrotum/testis sympt/compl other
4.9
7.2
22
46
KFW96
NOMESCO Finland
Other operation on scrotum or scrotal organs
30.3
7.2
9
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
7.1
176
1173
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.2
7.1
75
369
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
3.3
6.8
33
105
N43.4
ICD-10 Finland
Spermatocele
3.3
6.8
33
105
R31
ICD-10 Finland
Unspecified haematuria
1.9
6.6
101
576
M02AA10
ATC
ketoprofen; topical
1.9
6.6
92
509
C60.9
ICD-10 Finland
Malignant neoplasm: Penis, unspecified
70.5
6.4
7
*
116
Kela drug reimbursment
Prostate cancer
2.1
6.4
75
387
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
6.3
118
720
KFD70
NOMESCO Finland
Excision of lesion of skin of scrotum
+∞
6.3
6
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
6.2
121
748
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
6.2
106
627
N02BE01
ATC
paracetamol; systemic, rectal
1.6
6.1
515
4535
C05AA08
ATC
fluocortolone; rectal, topical
1.9
6.0
89
499

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
41
24
18.03
50.03
4.0
2.4
31.7
63.8
u/l
—
6
5
279
1980
1.66
9.53
2.3
2.3
—
—
—
0
0
348
2696
1.55
7.79
8.9
11.5
1.3
1.4
inr
0.38
110
741
509
4299
1.59
7.71
6.4
5.1
2.7
3.0
ug/l
0.22
444
3830
11
15
7.43
7.57
1.9
4.6
—
—
—
0
0
433
3537
1.54
7.50
5.1
4.2
142.9
1425.6
e6/l
—
9
62
451
3757
1.52
6.83
5.1
4.0
—
—
—
0
0
134
867
1.67
6.22
2.6
2.3
12.2
13.4
nmol/l
0.91
109
772
372
3026
1.46
6.02
6.7
7.1
11.8
13.2
umol/l
2.07
359
2886
95
574
1.75
5.65
5.9
4.9
—
—
—
0
0
501
4359
1.47
5.43
8.7
8.3
78.2
80.6
u/l
0.55
467
4108
111
714
1.65
5.24
1.2
1.4
—
—
—
0
0
232
1767
1.46
5.09
5.1
4.2
—
—
—
0
0
527
4655
1.46
5.08
3.9
3.8
1.9
2.0
mu/l
1.29
461
4180
66
369
1.87
5.07
2.5
3.2
4.0
4.2
e9/l
0.22
43
282
36
161
2.30
4.99
1.7
1.4
6.3
6.0
u/l
0.05
26
129
606
5535
1.53
4.68
18.1
17.0
28.3
29.8
mg/l
0.41
503
4509
345
2859
1.39
4.59
8.1
8.1
1.2
1.2
mmol/l
0.34
277
2409
416
3565
1.38
4.46
5.1
5.6
6.6
6.9
mmol/l
2.42
398
3385
318
2623
1.37
4.25
4.1
4.4
—
—
—
0
0
227
1773
1.41
4.21
2.3
2.2
293.8
302.7
u/l
0.03
213
1661
317
2621
1.37
4.15
7.2
7.2
1.2
1.2
mmol/l
0.69
278
2384
316
2613
1.37
4.12
6.2
6.5
9.0
9.2
%
0.37
290
2466
321
2666
1.36
4.05
6.1
6.3
25.1
25.8
%
0.50
291
2504
315
2615
1.36
3.97
5.6
6.1
59.3
58.5
%
0.51
285
2470
313
2599
1.36
3.92
5.9
6.2
2.7
2.9
%
1.10
286
2445
231
1831
1.38
3.87
3.1
2.9
57.5
57.3
u/l
0.03
217
1709
452
3980
1.35
3.79
4.3
3.9
12.8
12.8
mm/h
0.01
411
3657
620
5763
1.48
3.67
21.5
20.2
139.7
139.6
mmol/l
0.19
601
5618
337
2850
1.34
3.67
5.6
6.2
0.2
0.2
e9/l
1.29
294
2506
304
2536
1.34
3.62
6.0
6.2
0.6
0.6
%
0.03
276
2398
242
1951
1.36
3.61
6.1
6.0
—
—
—
0
0
256
2084
1.35
3.58
2.8
2.8
184.1
203.0
ug/l
0.55
229
1903
621
5784
1.47
3.54
21.6
20.4
4.0
4.0
mmol/l
0.78
602
5636
76
492
1.61
3.52
1.2
1.4
—
—
—
0
0
324
2765
1.31
3.16
5.4
5.9
0.6
0.6
e9/l
0.55
280
2373
366
3176
1.30
3.15
9.1
9.4
4.5
4.4
e9/l
0.39
328
2769
324
2772
1.30
3.08
5.5
5.9
0.0
0.0
e9/l
0.40
280
2394
612
5724
1.41
3.04
18.8
16.1
—
—
—
0
0
51
311
1.69
3.00
5.1
4.2
24.0
24.9
mmol/l
1.81
44
290
329
2828
1.30
3.00
5.5
6.1
1.7
2.0
e9/l
1.60
288
2480
648
6136
1.46
2.89
26.8
24.1
229.9
230.4
e9/l
0.07
631
5957
648
6140
1.46
2.84
26.7
24.0
30.5
30.6
pg
1.09
636
6028
648
6140
1.46
2.84
26.7
24.1
91.2
91.5
fl
0.71
635
6029
281
2379
1.29
2.84
2.0
2.1
93.3
91.9
pmol/l
0.15
153
1350
648
6141
1.46
2.82
26.8
24.1
4.6
4.6
e12/l
0.17
626
5944
225
1851
1.31
2.81
2.8
2.8
—
—
—
0
0
648
6142
1.46
2.81
27.0
24.3
138.0
139.1
g/l
0.79
636
6026
648
6143
1.45
2.80
26.8
24.2
7.0
7.0
e9/l
0.15
628
5947
29
153
1.93
2.74
4.9
5.2
3.0
2.3
mmol/l
0.46
20
100
57
367
1.60
2.74
3.0
2.8
—
—
—
0
0
229
1898
1.30
2.69
4.1
3.5
42.0
116.1
e6/l
1.25
191
1521
401
3566
1.27
2.69
3.0
3.0
15.0
15.0
pmol/l
0.10
353
3179
167
1329
1.33
2.62
3.2
2.7
2.7
3.0
e6/l
0.32
148
1162
48
304
1.62
2.48
1.9
1.9
38.0
38.8
nmol/l
0.08
48
292
49
316
1.59
2.36
1.9
2.0
1.2
1.3
ug/l
0.06
37
278
97
723
1.39
2.31
1.5
1.3
—
—
—
0
0
281
2436
1.25
2.21
4.3
4.0
43.0
57.7
ng/l
0.80
220
1848
229
1940
1.26
2.20
3.3
3.2
2101.7
1928.7
ng/l
0.17
190
1686
232
1971
1.26
2.17
4.4
4.7
—
—
—
0
0
36
221
1.66
2.13
1.6
1.6
—
—
—
0
0
173
1422
1.28
2.12
2.7
2.7
—
—
—
0
0
194
1627
1.26
2.02
3.8
3.4
—
—
—
0
0
111
869
1.33
1.95
2.9
2.9
22.1
24.0
%
0.80
96
749
146
1187
1.29
1.95
1.8
1.8
1155.4
1168.7
nmol/l
0.04
101
914
181
1512
1.26
1.94
2.2
2.1
3.0
3.0
mg/l
0.06
153
1294
164
1355
1.27
1.93
3.2
3.2
—
—
—
0
0
115
907
1.32
1.92
31.1
29.8
1.4
1.4
inr
0.01
12
120
530
4960
1.24
1.92
17.7
17.7
41.3
40.7
%
0.88
337
3352
27
158
1.74
1.91
3.8
4.0
—
—
—
0
0
116
921
1.31
1.85
2.7
2.8
2.1
2.2
g/l
0.80
103
861
618
5898
1.30
1.84
12.0
10.9
28.6
29.6
u/l
0.48
588
5690
240
2084
1.22
1.80
4.7
3.9
56.4
133.4
e6/l
1.12
192
1599
8
29
2.78
1.79
18.9
12.5
—
—
—
0
0
8
29
2.78
1.79
2.1
2.9
—
—
—
0
0
578
5479
1.25
1.77
4.6
4.6
4.3
4.4
mmol/l
0.23
514
5033
10
41
2.46
1.76
4.7
4.4
7.4
7.4
ph
—
5
14
15
74
2.05
1.76
1.7
1.4
45.0
61.2
pmol/l
—
7
23
60
434
1.42
1.73
3.4
2.7
—
—
—
0
0
200
1716
1.23
1.67
3.9
3.4
0.6
0.5
e6/l
0.08
161
1342
152
1266
1.25
1.67
3.2
2.9
597.5
590.8
mosm/kgh2o
0.15
133
1076
25
150
1.69
1.65
1.4
1.6
—
—
—
0
0
101
801
1.30
1.64
2.5
2.5
1.7
1.8
%
0.57
90
726
48
338
1.45
1.61
1.3
1.8
1.7
1.5
g/l
0.72
39
300
72
545
1.36
1.61
3.2
2.8
65.9
65.9
g/l
0.01
60
500
16
84
1.92
1.60
7.2
5.3
—
—
—
0
0
19
106
1.81
1.60
5.7
4.7
2.8
1.1
%
0.50
14
94
42
289
1.48
1.59
2.6
2.4
—
—
—
0
0
79
609
1.33
1.57
2.3
2.7
68.9
68.2
e9/l
0.07
62
483
78
601
1.33
1.56
1.6
1.6
—
—
—
0
0
121
990
1.27
1.55
2.7
2.8
12.2
13.0
umol/l
0.57
110
928
557
5285
1.22
1.54
4.2
4.1
1.3
1.3
mmol/l
0.16
490
4795
287
2570
1.19
1.52
5.3
5.7
34.7
34.9
g/l
0.20
259
2394
95
756
1.29
1.51
2.0
1.8
—
—
—
0
0
278
2488
1.19
1.47
3.6
3.1
0.7
0.8
ug/l
1.65
201
1655
15
81
1.87
1.41
2.7
2.6
—
—
—
0
0
50
366
1.39
1.39
4.9
3.9
—
—
—
0
0
190
1651
1.20
1.38
5.5
4.5
7.4
7.4
ph
0.68
50
318
584
5587
1.22
1.38
5.0
5.1
2.6
2.6
mmol/l
0.28
520
5091
563
5368
1.21
1.38
5.2
4.8
6.0
6.1
mmol/l
1.54
492
4835
38
265
1.46
1.37
1.2
1.2
—
—
—
0
0
569
5435
1.21
1.34
4.8
4.6
1.3
1.3
mmol/l
0.87
508
4951
29
192
1.53
1.34
1.3
2.6
37.9
37.0
g/l
0.29
22
162
77
609
1.30
1.30
1.4
1.4
—
—
—
0
0
60
458
1.34
1.30
4.0
4.7
0.1
0.2
%
0.72
17
160
85
1049
0.79
1.30
4.2
3.4
2.5
2.4
mmol/l
0.31
76
924
13
69
1.90
1.29
6.2
4.7
66.3
55.7
%
—
6
57
65
504
1.32
1.27
4.8
3.7
5.0
5.2
kpa
0.89
59
467
9
44
2.06
1.27
2.9
2.6
—
—
—
0
0
64
496
1.32
1.26
4.9
3.8
7.4
7.4
ph
—
6
57
32
221
1.47
1.23
1.9
1.7
—
—
—
0
0
166
1441
1.20
1.22
1.5
1.6
18.5
19.0
nmol/l
0.18
137
1230
13
71
1.85
1.20
1.2
1.1
—
—
—
0
0
37
265
1.42
1.19
2.4
2.5
212.6
631.2
ug/l
1.36
32
257
76
610
1.27
1.17
1.8
1.8
—
—
—
0
0
5
114
0.43
1.13
1.2
1.4
—
—
—
0
0
13
73
1.79
1.11
1.3
2.3
—
—
—
0
0
51
391
1.33
1.10
4.9
5.2
109.9
113.7
ng/l
0.07
45
345
152
1322
1.19
1.10
6.7
6.7
—
—
—
0
0
8
41
1.96
1.09
4.1
3.2
—
—
—
0
0
122
1041
1.21
1.09
4.1
3.6
0.8
0.8
mmol/l
0.98
113
982
7
33
2.13
1.05
1.4
1.1
—
—
—
0
0
56
439
1.30
1.04
3.8
4.3
1.4
0.5
%
0.81
14
132
5
22
2.28
1.03
1.0
1.0
—
—
—
0
0
5
22
2.28
1.03
1.4
1.1
—
—
—
0
0
18
114
1.59
1.03
3.4
3.4
62.9
56.7
%
1.13
18
114
61
485
1.28
1.03
3.9
4.6
1.0
0.9
%
0.14
17
174
190
1694
1.16
1.02
3.2
3.0
2658.2
6297.1
umol/l
0.77
168
1473
54
423
1.30
1.02
4.0
4.8
0.1
0.1
%
0.22
15
139
22
147
1.51
1.01
2.6
3.0
—
—
—
0
0
50
388
1.31
1.01
1.5
1.6
—
—
—
0
0
139
1212
1.18
0.98
3.9
3.9
218.3
422.9
ng/l
0.86
119
1022
120
1033
1.19
0.98
3.5
3.2
1.3
0.6
e6/l
0.75
77
637
74
607
1.24
0.97
3.1
2.5
0.2
0.2
g/l
0.01
68
554
24
166
1.46
0.95
3.4
3.1
—
—
—
0
0
17
109
1.57
0.94
3.2
3.1
5.1
4.4
e9/l
0.40
17
109
8
143
0.55
0.94
3.3
3.1
—
—
—
0
0
35
263
1.35
0.89
1.2
1.2
—
—
—
0
0
82
688
1.22
0.89
2.9
3.2
9.3
11.1
umol/l
0.23
71
622
9
156
0.57
0.89
1.0
1.1
—
—
—
0
0
146
1291
1.16
0.88
1.7
1.7
112820946.8
19739701.0
pmol/l
0.60
117
1074
24
333
0.71
0.87
1.2
1.4
—
—
—
0
0
30
223
1.36
0.83
1.1
1.3
—
—
—
0
0
173
1911
0.88
0.80
3.0
2.9
—
—
—
0
0
74
622
1.21
0.80
3.1
4.2
2.4
1.8
mmol/l
0.97
56
496
277
2574
1.12
0.79
5.1
4.6
0.0
0.0
estimate
0.00
58
503
12
74
1.63
0.78
1.3
1.2
—
—
—
0
0
44
351
1.27
0.76
1.9
1.7
1.1
1.6
g/l
0.82
37
328
10
59
1.70
0.76
1.0
1.2
—
—
—
0
0
280
2610
1.12
0.75
3.9
3.5
0.0
0.0
estimate
0.00
55
469
18
124
1.46
0.75
1.5
1.8
—
—
—
0
0
5
24
2.09
0.74
1.4
1.7
—
—
—
0
0
537
5193
1.13
0.73
6.9
6.3
40.6
40.9
mmol/mol
0.30
469
4785
20
142
1.42
0.73
2.0
1.5
—
—
—
0
0
5
25
2.01
0.72
3.0
1.2
0.2
0.2
nmol/l
—
5
16
5
25
2.01
0.72
1.8
1.2
—
—
—
0
0
7
39
1.80
0.72
1.7
1.5
—
—
—
0
0
16
110
1.46
0.69
2.6
2.2
—
—
—
0
0
63
531
1.20
0.68
3.8
3.5
—
—
—
0
0
88
765
1.17
0.68
1.8
1.8
—
—
—
0
0
11
166
0.66
0.65
4.7
2.9
7.1
7.9
kpa
1.31
11
151
102
904
1.15
0.62
7.9
7.1
1.1
1.0
mmol/l
0.85
94
849
72
621
1.18
0.62
1.3
1.3
248.0
372.0
titre
—
10
113
35
280
1.26
0.62
3.2
3.9
—
—
—
0
0
18
130
1.39
0.61
3.7
2.0
0.9
0.8
nmol/l
0.22
13
113
19
139
1.38
0.61
3.4
3.8
37.8
29.8
mg/l
0.18
11
93
11
163
0.67
0.60
3.7
9.7
104.4
105.5
mmol/l
0.44
11
145
11
163
0.67
0.60
3.7
9.7
10.5
11.8
mmol/l
0.80
11
145
31
388
0.79
0.60
12.1
13.7
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
1394.4
—
0
20
71
614
1.17
0.60
6.6
8.8
1.5
1.4
mmol/l
0.20
66
591
276
2600
1.10
0.59
4.0
3.4
0.0
0.0
estimate
0.00
57
488
6
36
1.67
0.56
1.0
1.5
—
—
—
0
0
153
1402
1.12
0.56
3.9
3.1
—
—
—
0
0
68
590
1.17
0.56
8.1
10.5
—
—
—
0
0
6
98
0.61
0.52
1.0
1.3
—
—
—
0
0
48
408
1.19
0.51
1.5
1.5
—
—
—
0
0
7
45
1.56
0.49
2.1
1.6
—
—
—
0
0
7
46
1.53
0.48
1.1
1.1
—
—
—
0
0
29
236
1.24
0.47
4.1
3.8
0.3
0.3
g/l
0.27
22
115
48
556
0.85
0.46
1.5
1.4
—
—
—
0
0
55
478
1.16
0.46
1.7
2.2
376.3
365.0
nmol/l
0.17
49
435
33
274
1.21
0.45
1.7
1.3
—
10.7
—
0
10
38
448
0.84
0.45
1.2
1.4
—
—
—
0
0
75
669
1.13
0.45
7.5
8.7
10.9
11.0
mmol/l
0.05
69
639
134
1449
0.91
0.44
1.7
1.7
1.4
1.4
mmol/l
0.07
115
1186
19
148
1.29
0.44
2.5
1.9
14.2
12.4
mg/l
0.39
19
136
13
96
1.36
0.41
1.2
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
51
446
1.15
0.41
3.1
2.5
10.5
11.4
g/l
0.81
44
407
21
168
1.26
0.40
3.4
4.6
—
—
—
0
0
0
19
0.00
0.39
0.0
7.9
—
—
—
0
0
19
151
1.27
0.39
1.2
1.4
1.1
1.2
g/l
0.87
19
145
124
1151
1.09
0.38
4.6
4.8
—
—
—
0
0
156
1463
1.08
0.38
4.4
3.7
0.0
0.0
estimate
0.69
56
459
9
70
1.29
0.36
4.1
3.8
—
—
—
0
0
44
500
0.87
0.35
3.8
5.5
—
—
—
0
0
6
45
1.34
0.34
1.2
1.3
—
—
—
0
0
13
166
0.78
0.33
1.5
1.2
—
—
—
0
0
22
182
1.22
0.33
5.6
3.6
—
—
—
0
0
48
539
0.88
0.33
1.4
1.4
—
—
—
0
0
53
590
0.89
0.32
2.6
3.0
307.7
228.7
ng/l
0.39
47
534
13
101
1.29
0.32
2.5
2.6
—
—
—
0
0
39
343
1.14
0.31
2.5
2.8
—
—
—
0
0
32
277
1.16
0.31
1.0
1.2
—
—
—
0
0
7
97
0.72
0.31
1.1
1.6
—
—
—
0
0
7
53
1.32
0.31
1.1
1.2
—
—
—
0
0
76
699
1.10
0.29
1.2
1.2
53.8
38.4
iu/ml
0.20
22
197
18
148
1.22
0.29
1.2
1.3
0.2
0.2
g/l
0.67
18
141
10
129
0.77
0.28
1.0
1.4
—
—
—
0
0
9
120
0.75
0.27
12.6
3.6
—
—
—
0
0
26
224
1.17
0.27
2.0
1.7
—
—
—
0
0
8
67
1.20
0.26
1.0
1.2
—
—
—
0
0
5
72
0.69
0.26
1.0
1.1
—
—
—
0
0
5
72
0.69
0.26
1.0
1.1
—
—
—
0
0
17
203
0.83
0.26
3.2
2.4
101.2
117.3
ug/min
—
9
118
12
149
0.80
0.26
1.4
1.6
188.6
263.0
ug/g
—
7
94
9
74
1.22
0.25
1.2
1.2
—
—
—
0
0
11
137
0.80
0.24
1.2
1.4
—
—
—
0
0
249
2410
1.05
0.24
10.7
10.4
0.0
0.0
e9/l
0.26
206
1971
13
106
1.23
0.23
1.2
1.3
—
—
—
0
0
16
189
0.84
0.22
3.1
3.4
37.4
35.3
umol/l
—
10
155
7
94
0.74
0.22
1.0
1.5
—
—
—
0
0
5
40
1.25
0.22
3.6
1.2
182.8
147.7
nmol/l
—
5
40
69
643
1.08
0.22
1.3
1.2
2.6
12.9
u/ml
2.49
23
241
119
1132
1.06
0.21
1.6
1.6
1.3
1.5
mg/l
0.33
92
884
0
11
0.00
0.21
0.0
1.2
—
1.2
—
0
11
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
3.2
—
—
—
0
0
5
43
1.16
0.21
5.0
3.3
—
—
—
0
0
0
13
0.00
0.21
0.0
3.2
—
—
—
0
0
0
13
0.00
0.21
0.0
6.4
—
—
—
0
0
52
480
1.09
0.20
5.3
3.6
—
—
—
0
0
6
48
1.25
0.20
1.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
9.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
1.0
1.2
—
—
—
0
0
12
144
0.83
0.20
1.8
2.4
121.7
130.4
g/l
—
6
111
6
53
1.13
0.18
3.0
1.5
10.1
11.5
%
—
6
53
7
58
1.21
0.18
1.6
1.3
—
—
nmol/l
—
0
0
36
329
1.10
0.18
2.4
3.8
25.1
25.0
mmol/l
0.07
36
316
18
157
1.15
0.17
4.1
2.5
—
—
—
0
0
85
894
0.94
0.17
1.7
1.4
2.5
2.8
g/l
1.38
56
577
78
820
0.95
0.16
7.7
9.2
1.3
1.0
mmol/l
0.29
65
629
450
4443
1.03
0.15
21.2
20.4
13.8
13.8
%
0.00
441
4341
152
1473
1.04
0.15
1.3
1.3
—
—
—
0
0
15
131
1.15
0.14
1.2
1.1
—
—
—
0
0
13
112
1.16
0.14
1.4
1.2
—
—
—
0
0
193
1979
0.97
0.14
4.8
4.2
12.6
11.3
mg/mmol
0.09
129
1377
27
247
1.10
0.13
1.1
1.3
293.8
240.1
u/ml
0.11
22
220
11
128
0.86
0.13
1.5
1.4
—
—
—
0
0
11
94
1.17
0.13
3.7
3.7
—
—
—
0
0
9
107
0.84
0.13
1.9
2.5
—
—
—
0
0
79
824
0.95
0.12
7.5
9.1
11.6
11.8
kpa
0.20
74
792
73
698
1.05
0.12
1.5
1.5
—
—
—
0
0
398
4030
0.97
0.12
3.9
4.2
—
—
—
0
0
79
823
0.96
0.12
7.5
9.1
5.0
5.1
kpa
0.46
72
789
65
622
1.05
0.11
2.0
2.5
7.4
8.7
ug/l
0.35
51
557
124
1205
1.03
0.11
3.7
3.5
—
—
—
0
0
25
270
0.92
0.10
1.5
1.4
—
—
—
0
0
61
636
0.96
0.10
4.2
4.4
4.5
35.5
ug/l
1.58
53
536
183
1866
0.97
0.09
3.8
3.5
63.0
260.0
mg/l
1.97
124
1310
5
46
1.09
0.09
12.8
4.1
—
—
—
0
0
193
1966
0.98
0.09
3.9
3.4
8.1
8.5
mmol/l
0.66
153
1644
17
155
1.10
0.09
1.1
1.2
—
1.5
—
0
13
6
58
1.03
0.08
1.2
1.2
—
—
—
0
0
6
58
1.03
0.08
1.5
1.2
—
—
—
0
0
5
61
0.82
0.08
1.0
1.2
2.0
1.5
nmol/l
—
5
55
5
60
0.83
0.08
1.4
1.3
—
—
—
0
0
27
287
0.94
0.08
6.0
4.6
—
—
—
0
0
18
166
1.09
0.08
4.2
2.2
—
—
—
0
0
184
1811
1.02
0.07
3.9
3.6
2.3
2.3
mmol/l
0.62
152
1589
7
80
0.87
0.07
1.4
1.4
—
—
—
0
0
7
83
0.84
0.07
1.9
3.1
—
—
—
0
0
7
84
0.83
0.07
1.3
1.8
—
—
—
0
0
7
84
0.83
0.07
1.3
1.8
—
—
—
0
0
7
84
0.83
0.07
1.3
1.8
—
—
—
0
0
7
84
0.83
0.07
1.3
1.8
—
—
—
0
0
9
86
1.05
0.07
1.3
1.5
—
—
—
0
0
50
517
0.96
0.06
2.7
2.7
154.5
164.7
ug/g
0.10
39
432
18
168
1.07
0.06
4.1
2.4
—
—
—
0
0
98
960
1.02
0.06
1.9
2.3
—
—
—
0
0
117
1191
0.98
0.05
4.7
3.8
1.0
1.0
kg/l
0.05
19
167
91
929
0.98
0.05
1.2
1.2
1.7
1.2
u/ml
0.20
23
255
22
208
1.06
0.05
1.4
1.8
20.9
22.5
s
0.73
16
191
14
150
0.93
0.04
1.2
1.2
—
—
—
0
0
11
101
1.09
0.04
1.2
1.1
—
—
—
0
0
18
170
1.06
0.04
4.1
2.4
—
—
—
0
0
18
170
1.06
0.04
4.1
2.4
—
—
—
0
0
19
199
0.95
0.03
1.3
1.1
27.6
141.6
iu/ml
—
9
67
19
199
0.95
0.03
3.6
3.2
25.1
24.7
mmol/l
0.18
19
172
31
319
0.97
0.02
1.5
1.2
—
—
—
0
0
13
124
1.05
0.00
1.2
1.0
—
—
—
0
0
19
184
1.03
0.00
16.2
12.8
—
—
—
0
0
10
104
0.96
0.00
3.5
1.4
—
—
—
0
0
13
133
0.98
0.00
3.2
2.5
—
—
—
0
0
21
213
0.99
0.00
1.1
1.1
—
—
—
0
0
10
101
0.99
0.00
1.1
1.1
—
—
—
0
0
12
121
0.99
0.00
1.2
1.5
25.9
31.1
g/l
0.68
12
107
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
4.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
4.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
17.0
—
0
7
0
9
0.00
0.00
0.0
1.3
—
92.7
—
0
9
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
11
110
1.00
0.00
1.2
1.5
1550.2
1833.0
e6/l
0.13
11
81
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
2.4
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
7
75
0.93
0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.1
—
0
5
6
67
0.89
0.00
11.3
4.1
—
—
—
0
0
5
51
0.98
0.00
1.4
1.1
—
—
—
0
0
6
60
1.00
0.00
1.5
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
6
60
1.00
0.00
3.0
2.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MALE_GEN and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MALE_GEN 1.301 [1.15, 1.47] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 965 out of 3809 males with CD2_BENIGN_MALE_GEN died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MALE_GEN.

N-year risk Females Males
1 No data 0.238%
5 No data 1.447%
10 No data 3.479%
15 No data 6.681%
20 No data 11.102%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MALE_GEN – Benign neoplasm of male genital organs

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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