Benign neoplasm: Epididymis

CD2_BENIGN_EPIDIDYMIS

testicular carcinoma: A primary or metastatic malignant neoplasm that affects the testis. Representative examples include seminoma, embryonal carcinoma, sarcoma, leukemia, and lymphoma.

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Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule only males	226754
2. Check conditions None	226754
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D29.3& Hospital discharge: ICD-9 — 2223 Cause of death: ICD-10 — D29.3& Cause of death: ICD-9 — 2223 2 out of 7 registries used, show all original rules.	123
4. Check minimum number of events None	123
5. Include endpoints None	123
6. Filter based on genotype QC (FinnGen only)	118

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D29
Name in latin: Neoplasma benignum epididymidis

NAME	CD2_BENIGN_EPIDIDYMIS
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	1
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D293
HD_ICD_9	2223
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D293
COD_ICD_9	2223
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Epididymis based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	908	-	908
Only index persons	837	-	837
Unadjusted period prevalence (%)
Whole population	0.03	-	0.03
Only index persons	0.03	-	0.03
Median age at first event (years)
Whole population	-	-	51.60
Only index persons	-	-	50.67

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	118	-	118
Unadjusted period prevalence (%)	0.05	-	0.05
Median age at first event (years)	54.12	-	54.12

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
123: Matched controls
1230

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D29.3

ICD-10 Finland

Benign neoplasm: Epididymis

+∞

137.7

105

KFD16

NOMESCO Finland

Partial excision of epididymis

109.0

24.7

2223A

ICD-9 Finland

Benign neoplasm of male genital organs, Epididymis

+∞

19.3

KF8AE

NOMESCO Finland

Ultrasound examination of scrotum

9.9

10.6

D40.1

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Testis

36.0

10.6

N43.4

ICD-10 Finland

Spermatocele

9.0

8.7

D40.7

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Other male genital organs

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

428

2.03

3.65

4.9

7.5

1.21

1.20

mmol/l

0.20

370

(40768804) Tissue Pathology biopsy report

323

2.06

3.63

1.8

2.0

—

(3002582) Erythrocytes [#/volume] in Urine

307

1.99

3.28

3.4

2.8

36.74

268.18

e6/l

0.57

239

(3022217) INR in Platelet poor plasma by Coagulation assay

489

1.87

2.92

15.9

13.7

1.26

1.30

inr

0.10

142

(3026008) Bacteria identified in Urine by Culture

204

2.00

2.81

2.4

3.1

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

367

1.78

2.47

3.3

2.9

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

794

1.95

2.44

3.3

3.7

1.86

2.00

mu/l

0.56

714

(3037467) Urinalysis macro (dipstick) panel - Urine

617

1.78

2.40

4.3

3.8

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

115

1035

2.71

2.30

16.5

17.9

89.56

86.89

umol/l

0.55

115

1035

(3018095) Leukocytes [#/volume] in Urine

337

1.75

2.30

4.0

3.1

33.79

102.81

e6/l

0.44

254

(3030467) Casts [#/volume] in Urine by Automated count

276

1.79

2.30

3.5

2.8

0.42

0.55

e6/l

0.16

209

(3026782) Osmolality of Urine

195

1.87

2.22

3.8

2.9

589.50

588.61

mosm/kgh2o

0.01

166

(3042631) Mycobacterium sp identified in Specimen

5.16

2.09

2.2

1.6

—

(3018418) pH of Serum or Plasma

250

1.75

2.05

3.1

4.0

7.41

7.40

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

110

973

2.23

2.05

13.3

15.0

28.56

26.88

mg/l

0.19

785

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.77

1.91

3.3

2.4

—

(1761482) Bacteria [#/volume] in Urine by Culture

2.88

1.82

3.4

5.2

—

(40768443) Skin Pathology biopsy report

2.60

1.63

1.1

—

(36304419) Bacteria [Presence] in Urine

258

1.62

1.58

3.8

2.7

—

(3009542) Hematocrit [Volume Fraction] of Blood

116

1077

2.35

1.57

21.5

21.9

41.65

41.50

0.09

107

1019

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

422

1.55

1.56

2.5

2.7

—

(40768797) Stomach Pathology biopsy report

110

1.86

1.53

1.3

1.4

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

332

1.56

1.51

1.8

2.0

74.88

91.04

pmol/l

1.73

184

(40761511) CBC panel - Blood by Automated count

110

1001

1.94

1.44

13.7

14.7

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

585

1.51

1.40

4.5

5.1

6.84

6.98

mmol/l

0.20

559

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

1.18

0.0

1.5

—

(3002256) Pathology report gross observation

105

1.72

1.13

1.2

1.3

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

163

1.59

1.13

2.6

1.00

0.48

e6/l

0.38

(3022145) Colonoscopy Study observation

1.73

1.10

1.5

1.4

—

(3041096) Erythrocytes [Presence] in Urine by Automated

243

1.49

1.09

3.4

3.1

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

547

1.40

1.04

2.3

2.8

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

413

1.40

1.01

3.7

3.8

18.22

52.35

ng/l

2.85

305

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

176

1.53

1.01

2.3

2.5

2.63

0.85

e6/l

0.45

106

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

720

1.42

1.01

5.3

4.6

2.07

2.42

ug/l

0.30

648

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

102

934

1.54

0.99

4.8

4.6

5.93

6.26

mmol/l

2.15

856

(40768800) Prostate Pathology biopsy report

2.00

0.98

1.0

1.2

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.82

0.97

8.0

9.2

—

(3009261) Glucose [Presence] in Urine by Test strip

439

1.36

0.90

3.7

3.5

0.00

estimate

—

(3049717) Cytology report of Urine Cyto stain

1.92

0.89

4.5

2.7

—

(3000330) Specific gravity of Urine by Test strip

1.92

0.89

3.4

4.7

—

(3021601) Nitrite [Presence] in Urine by Test strip

431

1.36

0.87

5.2

4.7

0.00

estimate

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

309

1.38

0.86

4.3

2.9

61.24

71.60

u/l

0.30

290

(3018677) aPTT in Platelet poor plasma by Coagulation assay

165

1.48

0.86

1.8

1.9

30.56

29.72

0.18

160

(3019225) pH of Specimen

1.65

0.82

2.4

3.9

—

(3037522) Nuclear Ab [Titer] in Serum

110

0.52

0.76

1.7

1.3

—

292.73

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

576

1.31

0.75

4.5

4.1

20.53

21.98

0.32

266

(3019832) Treponema pallidum Ab [Presence] in Serum

1.84

0.74

1.3

1.8

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

120

0.56

0.72

1.3

1.4

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.59

0.71

6.0

6.4

26.27

24.31

mmol/l

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.67

0.68

1.3

1.2

—

(3016502) Oxygen saturation in Arterial blood

112

1.49

0.67

6.1

8.3

96.88

95.86

0.70

107

(3014576) Chloride [Moles/volume] in Serum or Plasma

139

1.43

0.65

6.4

7.2

105.32

104.21

mmol/l

0.47

139

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.61

0.0

1.2

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.60

0.0

1.3

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.54

0.60

2.0

1.8

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

124

1.43

0.59

6.4

7.9

4.97

5.02

kpa

0.11

116

(3027801) Oxygen [Partial pressure] in Arterial blood

124

1.43

0.59

6.4

7.9

12.74

11.61

kpa

0.36

118

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

751

1.28

0.58

7.4

8.0

77.60

78.92

u/l

0.13

720

(3035350) Ketones [Presence] in Urine by Test strip

433

1.26

0.57

3.9

3.5

0.00

0.01

estimate

—

(3044889) 12 lead EKG panel

688

1.23

0.49

3.9

4.1

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

283

0.77

0.48

4.5

3.7

2.31

2.33

mmol/l

0.43

252

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.39

0.45

1.3

1.9

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

172

0.73

0.44

1.2

1.3

0.92

1.14

u/ml

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.41

0.42

1.6

2.0

—

(4035726) Immunohistochemistry procedure

1.43

0.42

1.2

1.3

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

1.54

0.42

1.2

2.3

—

(3017044) Thyrotropin receptor Ab [Units/volume] in Serum

0.00

0.41

0.0

1.6

—

6.38

—

(3021788) Differential panel - Synovial fluid

0.00

0.41

0.0

1.1

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.41

0.0

1.4

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.41

0.0

1.2

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

2.8

—

3.01

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.41

0.0

4.9

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.49

0.41

1.0

1.6

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.49

0.41

1.6

2.1

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.40

0.0

1.2

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.39

0.0

1.1

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.39

0.0

1.1

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

908

0.82

0.39

6.8

6.4

40.49

41.56

mmol/mol

0.50

856

(4200892) Spirometry reversibility

0.64

0.37

1.2

1.4

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

0.61

0.36

1.2

1.7

—

(3013512) EKG study

287

1.20

0.35

4.0

4.2

—

(3021589) Normoblasts [#/volume] in Blood

423

1.18

0.34

10.4

10.5

0.00

0.01

e9/l

0.52

350

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

347

1.18

0.32

4.2

3.7

—

(40758558) Short blood count panel - Blood

223

1.21

0.31

7.4

6.4

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

920

1.20

0.31

13.4

13.9

79.21

81.91

ml/min/173m2

0.69

775

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

106

0.74

0.30

2.4

3.1

—

(3000492) Spirometry study

110

0.71

0.30

1.3

1.4

—

(3003694) ABO and Rh group [Type] in Blood

234

1.20

0.30

1.4

1.3

—

(3001604) Monocytes [#/volume] in Blood

467

1.16

0.29

5.4

6.3

0.65

0.62

e9/l

0.34

407

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

418

1.16

0.29

3.5

2.8

0.73

0.70

ug/l

0.09

265

(3006315) Basophils [#/volume] in Blood

468

1.15

0.29

5.4

6.3

0.04

e9/l

0.23

411

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

226

1.19

0.28

2.6

2.4

—

(3044640) Blood type and Crossmatch panel - Blood

296

1.16

0.25

2.7

2.5

—

(3042936) Bacteria identified in Isolate by Culture

157

0.81

0.24

1.5

2.0

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.33

0.23

1.8

2.1

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

949

1.16

0.22

4.2

4.1

1.33

1.39

mmol/l

0.34

869

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

164

1.19

0.22

1.5

2.0

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

176

0.83

0.21

5.5

3.8

0.80

0.82

mmol/l

0.20

163

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.21

0.0

2.1

—

(40760848) Basement membrane zone BP180 Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.4

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.21

0.0

1.6

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

0.21

0.0

2.3

—

35.27

—

(3000012) Reticulocyte production index

0.00

0.21

0.0

2.8

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

0.21

0.0

2.2

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.21

0.0

3.1

—

33.60

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.21

0.0

1.1

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

0.21

0.0

2.3

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

1.48

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.3

—

(3000494) Fungus identified in Specimen by Culture

108

1.23

0.21

1.5

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.0

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

14.9

—

1065.08

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3022621) pH of Urine by Test strip

1.24

0.20

1.7

1.9

—

(3044941) Cell count panel - Synovial fluid

0.00

0.20

0.0

1.1

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.20

0.0

1.3

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.20

0.0

1.1

—

(3023368) Bacteria identified in Blood by Culture

301

1.13

0.19

3.9

5.1

—

(3020682) Albumin/Creatinine [Ratio] in Urine

337

0.89

0.17

5.3

4.1

6.40

11.52

mg/mmol

0.71

235

(40761536) Microorganisms panel - Urine sediment

1.17

0.17

6.4

3.4

—

(40761535) Cells panel - Urine sediment

0.76

0.16

1.7

3.6

—

(3000991) Gas panel - Venous blood

1.20

0.15

8.1

7.8

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

200

0.88

0.13

3.9

3.6

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

116

0.85

0.12

1.4

1.6

—

(3017181) Myelocytes/100 leukocytes in Blood

1.18

0.11

7.5

3.7

0.40

1.12

—

(40760892) CBC W Ordered Manual Differential panel - Blood

441

1.07

0.09

7.3

6.8

—

(3009508) Creatinine [Moles/volume] in Urine

333

1.07

0.08

3.3

3.4

8.83

8.79

mmol/l

0.02

282

(3004588) Protein electrophoresis panel - Serum or Plasma

1.03

0.08

1.7

2.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.82

0.08

1.2

1.5

—

(3024354) Oxygen [Partial pressure] in Venous blood

1.05

0.07

2.3

2.9

4.26

4.66

kpa

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.13

0.07

1.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

109

1.11

0.06

5.8

8.9

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

110

0.90

0.05

1.3

1.5

—

(1761868) Lipid panel - Serum or Plasma

372

0.95

0.04

3.5

3.0

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

141

1.07

0.03

2.0

1.8

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

301

1.04

0.02

1.6

2.3

72.70

72.03

nmol/l

0.04

267

(3029937) Albumin [Presence] in Urine by Test strip

238

0.96

0.02

4.7

3.7

0.00

0.02

estimate

—

(3012516) Albumin [Mass/volume] in Urine

312

1.03

0.02

3.7

3.5

28.92

76.15

mg/l

1.72

226

(3021447) Carbon dioxide [Partial pressure] in Venous blood

103

1.07

0.02

2.5

4.3

6.11

5.70

kpa

0.89

(3007853) Bacteria identified in Skin by Aerobe culture

101

0.99

0.00

1.6

1.9

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

119

1.01

0.00

1.3

2.0

—

(21494755) Public health laboratory ask at order entry panel

112

0.98

0.00

1.4

1.5

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

115

1.05

0.00

1.2

1.9

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

0.0

1.1

—

9.47

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.5

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.1

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

0.0

9.0

—

0.56

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

1.08

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.9

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.0

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

1.1

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

4.66

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.0

1.4

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.9

—

(3044007) Cell count panel - Peritoneal fluid

0.00

0.0

1.5

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

0.84

-0.00

2.8

2.7

0.74

0.65

—

(3041067) Sjogrens syndrome-A extractable nuclear 52kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

-0.00

0.0

1.4

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3043410) Blood group antigens tested for on Red Blood Cells

0.00

-0.00

0.0

1.2

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.00

-0.00

1.1

1.5

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

-0.00

0.0

1.0

—

10.94

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.02

-0.00

1.6

1.4

—

(3017315) Amylase [Enzymatic activity/volume] in Urine

0.00

-0.00

0.0

1.4

—

138.20

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.92

-0.00

2.8

1.6

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3035880) pH of Pleural fluid

0.00

-0.00

0.0

1.2

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

2.4

—

(3027831) CD3-CD16+CD56+ (Natural killer) cells/100 cells in Blood

0.00

-0.00

0.0

2.8

—

5.60

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

1.0

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.01

-0.00

1.8

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3012215) Mononuclear cells/100 leukocytes in Synovial fluid

0.00

-0.00

0.0

1.0

—

34.20

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.00

-0.00

2.5

2.8

1.12

1.57

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

-0.00

0.0

1.0

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

1.0

—

(3019060) Gas panel - Arterial blood

0.90

-0.00

2.6

4.6

—

(3022313) Gas panel - Capillary blood

0.87

-0.00

5.0

2.5

—

(3004451) EKG impression Narrative

0.00

-0.00

0.0

1.3

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.4

—

(3022493) Free Hemoglobin [Mass/volume] in Plasma

0.00

-0.00

0.0

1.0

—

49.40

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

1.02

-0.00

4.9

2.6

0.03

2.09

mmol/l

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

1.8

—

(3025577) Chromium [Mass/volume] in Blood

0.00

-0.00

0.0

2.0

—

2.08

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

-0.00

0.0

2.0

—

3.58

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.2

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.7

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

1.52

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.2

—

(3050898) Methicillin resistant Staphylococcus aureus [Presence] in Genital specimen by Organism specific culture

0.00

-0.00

0.0

1.8

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

-0.00

0.0

1.2

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_EPIDIDYMIS and mortality.

Females

No data

Males

Parameter	HR [95% CI]	p-value
CD2_BENIGN_EPIDIDYMIS	0.951 [0.75, 1.2]	0.673
Birth year	0.985 [0.98, 0.99]	0.003

During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 637 males with CD2_BENIGN_EPIDIDYMIS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_EPIDIDYMIS.

N-year risk	Females	Males
1	No data	0.15%
5	No data	1.044%
10	No data	2.681%
15	No data	5.038%
20	No data	8.452%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_EPIDIDYMIS – Benign neoplasm: Epididymis

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Epididymis

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints