Melanoma of uvea

CD2_UVEAMELANOMA_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF6

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 342 158 184
Unadjusted period prevalence (%) 0.07 0.05 0.08
Median age at first event (years) 64.02 61.76 65.96

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
300
Matched controls
3000
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
+∞
323.0
251
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
220.1
230.1
219
36
CKE60
NOMESCO Finland
Brachytherapy of choroid and retina
+∞
214.1
179
*
CKE65
NOMESCO Finland
Removal of brachytherapeutic plate from eye
+∞
212.7
178
*
C69.32
ICD-10 Finland
Malignant tumor of the chorioidea melanoma
+∞
181.2
155
*
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
434.1
151.5
140
6
WX140
NOMESCO Finland
Parabulbar anesthesy
65.8
145.1
167
56
XCK10
NOMESCO Finland
Photography of fundus of eye
22.7
111.8
184
195
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
17.4
86.2
152
167
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
19.9
82.1
133
115
C69.3
ICD-10 Finland
Malignant neoplasm: Choroid
+∞
79.8
73
*
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
80.5
70.7
78
13
8720/3-C69.3
ICD-O-3
Malignant melanoma, NOS, of choroid
+∞
67.3
62
*
8720/3-C69.9
ICD-O-3
Malignant melanoma, NOS, of eye, NOS
+∞
60.5
56
*
130
Kela drug reimbursment
Malignant tumour
+∞
59.4
55
*
C69.39
ICD-10 Finland
Malignant tumor in chorioidea other or unspecified histology
+∞
56.0
52
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
9.7
52.2
121
196
WX002
NOMESCO Finland
Sedation and analgesia
7.5
51.6
155
375
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
12.9
50.0
95
104
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
49.3
46
*
H02AB02
ATC
dexamethasone; systemic
29.2
33.4
45
18
C69.40
ICD-10 Finland
Malignant tumor of ciliary body without histology
+∞
32.9
31
*
A04AA02
ATC
granisetron; systemic, transdermal
127.3
32.4
34
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
31.8
30
*
ZXA00
NOMESCO Finland
Right side
4.5
31.2
153
564
ZXA05
NOMESCO Finland
Left side
4.5
30.7
151
556
Z51.5
ICD-10 Finland
Palliative care
19.4
29.5
45
27
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
27.5
26
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
27.5
26
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
26.4
25
*
1906B
ICD-9 Finland
Malignant neoplasm of eye, Choroid[MELANOMA CHORIOIDEAE]
+∞
25.4
24
*
A03FA01
ATC
metoclopramide; systemic, rectal
5.4
24.3
81
192
S01ED51
ATC
timolol, combinations; ophthalmic
6.2
23.9
69
137
N02AA05
ATC
oxycodone; systemic
5.2
23.7
83
207
115
Kela drug reimbursment
Breast cancer
+∞
23.2
22
*
JN4BD
NOMESCO Finland
Extensive body CT
8.6
22.3
50
68
CH2S4
NOMESCO Finland
Photography of iris
236.4
21.9
22
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.2
21.5
96
303
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
26.6
21.3
29
12
C69.02
ICD-10 Finland
Malignant tumor in conjunctival melanoma
+∞
21.1
20
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
21.1
20
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
20.2
20.9
31
17
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
20.0
19
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
6.5
19.1
52
94
3770
FHL
Placing a radiating plate on the surface of the eye with additional measures
+∞
18.9
18
*
C69.42
ICD-10 Finland
Malignant tumor of ciliary melanoma
+∞
18.9
18
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
18.0
18.2
28
17
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
17.8
174
958
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
25.9
17.6
24
10
WX142
NOMESCO Finland
Sub-tenon anesthesy
53.3
17.2
20
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.3
16.4
99
389
3779
FHL
Other operations in this group include disc removal
+∞
15.8
15
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
15.8
15
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
15.8
15
*
8000/3-C69.3
ICD-O-3
Neoplasm, malignant of choroid
+∞
15.8
15
*
CF2S4
NOMESCO Finland
Photography of conjunctiva
89.9
15.7
17
*
L02BG04
ATC
letrozole; oral
168.4
15.6
16
*
CD2S4
NOMESCO Finland
Photography of eye
84.3
14.7
16
*
C69.45
ICD-10 Finland
Melanoma of iris
+∞
14.7
14
*
JN4CD
NOMESCO Finland
Very extensive body CT
13.5
14.7
25
20
L01AX03
ATC
temozolomide; systemic
+∞
13.6
13
*
CDC00
NOMESCO Finland
Enucleation of eye
+∞
13.6
13
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
13.6
13
*
D31.4
ICD-10 Finland
Benign neoplasm: Ciliary body
+∞
13.6
13
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
13.6
13
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
13.6
13
*
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
146.3
13.6
14
*
A04AA01
ATC
ondansetron; systemic, rectal
11.3
13.5
25
24
116
Kela drug reimbursment
Prostate cancer
+∞
12.6
12
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
12.6
12
*
PC2ET
NOMESCO Finland
Extensive embolisation of lesion of liver
+∞
12.6
12
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
12.6
12
*
CDC10
NOMESCO Finland
Enucleation of eye with insertion of prosthesis
+∞
12.6
12
*
C69.99
ICD-10 Finland
Malignant tumor in unspecified localization in eye or other unspecified histology
+∞
12.6
12
*
180
Kela drug reimbursment
Interferon alfa
+∞
12.6
12
*
WF002
NOMESCO Finland
Radical radiotherapy
135.4
12.5
13
*
XCD20
NOMESCO Finland
Photoangiography of eye
8.8
12.3
26
32
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.4
12.3
158
941
WZC30
NOMESCO Finland
Teaching
4.1
12.2
49
135
H26.2
ICD-10 Finland
Complicated cataract
17.3
11.8
18
11
H33.2
ICD-10 Finland
Serous retinal detachment
67.6
11.7
13
*
S01ED01
ATC
timolol; ophthalmic
5.9
11.6
32
59
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
11.5
11
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
124.6
11.5
12
*
JN4AD
NOMESCO Finland
Body CT examination
6.6
11.4
29
48
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
36.6
11.4
14
*
A06AH03
ATC
naloxegol; oral
113.8
10.5
11
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
10.5
10
*
XX7GT
NOMESCO Finland
Selective internal radio therapy (SIRT) with Yttrium
+∞
10.5
10
*
HA1AA
NOMESCO Finland
X-ray mammography
7.5
10.0
23
33
XX3DW
NOMESCO Finland
Time consuming IT work
5.2
9.6
29
60
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
9.5
52
183
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
9.4
9
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
9.4
9
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
9.4
9
*
C69.00
ICD-10 Finland
Malignant tumor of the conjunctiva without histology
+∞
9.4
9
*
L01BC06
ATC
capecitabine; oral
+∞
9.4
9
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.4
9.2
89
443
ZXA10
NOMESCO Finland
Bilateral
2.5
8.9
79
377
H33.0
ICD-10 Finland
Retinal detachment with retinal break
7.0
8.8
21
32
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
51.5
8.7
10
*
L02AE02
ATC
leuprorelin; implant, parenteral
20.7
8.5
12
6
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
6.6
8.5
21
34
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
92.5
8.5
9
*
L03AA02
ATC
filgrastim; parenteral
92.5
8.5
9
*
C69.03
ICD-10 Finland
Malignant tumor of conjunctival carcinoma
+∞
8.4
8
*
C69.20
ICD-10 Finland
Retina
+∞
8.4
8
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
8.4
8
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
8.4
8
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
8.4
8
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
8.4
8
*
S01EC01
ATC
acetazolamide; systemic
6.0
8.0
21
37
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.9
8.0
32
89
CA1ME
NOMESCO Finland
Ultrasound oculometry
11.2
7.9
14
13
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
8.0
7.5
16
21
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.5
7.3
60
270
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.3
7
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
7.3
7
*
PC2DT
NOMESCO Finland
Embolisation of lesion of liver
+∞
7.3
7
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
7.3
7
*
L02BB03
ATC
bicalutamide; oral
+∞
7.3
7
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
20.6
7.2
10
5
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.0
6.9
129
835
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
7.5
6.8
15
21
H43.1
ICD-10 Finland
Vitreous haemorrhage
5.7
6.7
18
33
WX302
NOMESCO Finland
Thoracal epidural anesthesy
8.1
6.7
14
18
XCH00
NOMESCO Finland
Eye pressure measurement
4.4
6.7
23
56
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
12.6
6.6
11
9
D31.2
ICD-10 Finland
Benign neoplasm: Retina
71.3
6.4
7
*
L02BA01
ATC
tamoxifen; oral
71.3
6.4
7
*
L03AB05
ATC
interferon alfa-2b; parenteral
71.3
6.4
7
*
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
71.3
6.4
7
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
6.3
6
*
C79.41
ICD-10 Finland
Secondary malignant tumor of optic nerve and eye
+∞
6.3
6
*
CH3S4
NOMESCO Finland
Photography of iridocorneal angle
+∞
6.3
6
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
6.3
6
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
6.3
6
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
6.3
6
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
6.3
6
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
6.3
6
*
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
+∞
6.3
6
*
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
+∞
6.3
6
*
Y77
ICPC
Malignant neoplasm prostate
+∞
6.3
6
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
+∞
6.3
6
*
C67.0
ICD-10 Finland
Malignant neoplasm: Trigone of bladder
+∞
6.3
6
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
+∞
6.3
6
*
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
27.3
6.3
8
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
27.3
6.3
8
*
114
Kela drug reimbursment
Glaucoma
2.7
6.2
40
159
S01EA03
ATC
apraclonidine; ophthalmic
10.3
6.1
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
56
75
8.73
40.72
1.5
1.3
—
—
—
0
0
23
14
17.54
27.41
1.3
1.2
—
—
—
0
0
59
152
4.48
21.48
3.7
1.3
9.1
2.8
ug/l
0.89
47
117
212
1278
2.73
17.93
10.3
4.1
13.6
11.9
umol/l
0.64
207
1201
281
1988
3.32
17.11
14.5
5.4
90.6
76.3
u/l
2.41
271
1819
21
27
8.22
15.45
2.0
1.6
7.7
139.7
u/ml
0.46
21
27
31
62
5.40
15.09
2.6
1.7
19.3
205.6
u/ml
0.75
26
47
54
195
3.10
11.72
1.3
1.1
—
—
—
0
0
206
1399
2.19
11.08
13.6
6.0
4.1
4.3
e9/l
0.53
184
1226
140
833
2.15
10.42
6.6
5.4
—
—
—
0
0
132
799
2.06
9.13
2.6
1.6
—
—
—
0
0
125
744
2.07
9.04
2.6
2.1
—
—
—
0
0
190
1313
2.01
9.03
8.5
5.9
1.2
1.2
mmol/l
0.73
153
1120
13
18
7.47
8.90
1.5
1.1
—
—
—
0
0
169
1131
1.98
8.71
7.0
3.8
33.9
35.4
g/l
2.33
154
1033
19
43
4.62
8.00
4.5
2.7
53.1
58.6
%
0.63
19
43
106
617
2.04
7.98
5.4
3.4
88.8
87.1
%
0.29
106
597
11
15
7.54
7.59
1.5
1.5
—
—
—
0
0
172
1197
1.88
7.53
7.4
5.6
1.2
1.2
mmol/l
0.23
160
1059
18
42
4.47
7.31
3.6
2.3
4.2
4.6
e9/l
0.23
18
42
131
850
1.88
7.02
3.0
2.3
53.2
56.3
u/l
0.77
122
781
116
725
1.91
6.97
4.6
4.0
—
—
—
0
0
96
573
1.94
6.57
9.3
4.5
—
—
—
0
0
130
860
1.83
6.44
6.8
2.1
2.4
2.4
mmol/l
0.01
112
704
9
5
18.43
6.29
6.4
1.0
26.2
14.2
u/ml
—
9
5
159
1124
1.77
6.26
7.9
9.1
1.1
1.3
inr
1.95
50
303
87
522
1.89
5.79
2.9
2.6
475.6
543.3
mosm/kgh2o
2.71
80
421
154
1099
1.73
5.72
4.3
3.7
—
—
—
0
0
205
1608
1.69
5.18
5.8
4.7
6.9
6.9
mmol/l
0.08
193
1498
20
66
3.16
5.03
2.6
2.3
1.8
1.5
mg/l
0.57
20
58
23
86
2.80
4.68
4.7
2.2
0.4
0.3
g/l
—
10
26
157
1189
1.59
4.27
7.3
5.4
57.9
57.6
%
0.10
152
1091
112
785
1.63
4.17
5.2
3.3
7.4
7.4
ph
0.13
28
124
115
813
1.62
4.13
3.1
3.1
37.5
135.3
e6/l
0.63
95
628
53
301
1.90
4.10
1.9
1.7
—
—
—
0
0
39
199
2.08
4.07
1.5
1.5
—
—
—
0
0
165
1283
1.55
3.89
7.4
5.3
2.4
1.9
e9/l
0.68
145
1127
168
1312
1.55
3.88
7.4
5.4
0.2
0.2
e9/l
1.07
150
1146
245
2751
0.61
3.81
4.9
5.4
2.6
2.7
mmol/l
0.13
229
2501
39
206
2.01
3.72
1.5
1.4
—
—
—
0
0
46
258
1.90
3.70
6.9
3.4
—
—
—
0
0
8
12
6.79
3.69
2.9
1.5
19.2
17.3
ug/l
—
8
12
162
1268
1.53
3.63
7.4
5.2
0.0
0.0
e9/l
0.00
144
1100
54
321
1.81
3.62
6.9
5.3
1.1
1.0
mmol/l
1.23
47
285
161
1260
1.52
3.60
7.5
5.2
0.6
0.6
e9/l
0.65
144
1088
235
2655
0.63
3.60
4.3
4.8
1.4
1.5
mmol/l
0.84
221
2411
227
2583
0.64
3.58
6.2
6.6
41.2
40.8
mmol/mol
0.24
211
2383
10
26
3.93
3.54
1.8
1.2
36.8
26.3
g/l
—
10
21
127
948
1.54
3.52
3.7
3.6
95.9
105.7
e6/l
0.10
98
676
60
373
1.74
3.46
2.2
2.1
—
—
—
0
0
227
2575
0.65
3.40
3.9
4.3
1.4
1.3
mmol/l
1.29
213
2320
239
2679
0.64
3.34
4.5
4.8
4.5
4.5
mmol/l
0.35
222
2445
37
203
1.92
3.18
4.2
3.6
—
—
—
0
0
55
347
1.70
3.01
3.2
2.3
20.8
23.2
%
0.92
49
303
8
17
4.79
2.93
2.3
1.2
—
—
—
0
0
62
899
0.62
2.91
3.1
3.3
—
—
—
0
0
95
691
1.52
2.88
3.3
2.8
—
—
—
0
0
81
571
1.55
2.83
2.6
2.5
4.2
5.1
e6/l
0.48
74
485
9
23
3.99
2.79
1.1
1.7
290.0
269.8
mosm/kgh2o
—
9
16
98
732
1.47
2.59
3.4
2.9
0.6
0.5
e6/l
0.13
83
541
7
16
4.44
2.48
1.9
1.3
—
—
—
0
0
6
13
4.68
2.28
1.3
1.2
—
—
—
0
0
44
283
1.64
2.25
4.5
2.4
13.9
7.6
umol/l
0.56
37
245
247
2694
0.70
2.19
5.0
4.9
6.2
6.1
mmol/l
0.43
226
2412
7
20
3.55
2.06
1.6
1.2
—
—
—
0
0
7
20
3.55
2.06
1.3
1.3
—
—
—
0
0
5
11
4.59
1.95
1.0
2.1
3.4
4.8
nmol/l
—
5
11
284
2632
1.47
1.91
23.0
13.7
27.6
23.9
mg/l
0.94
246
2044
152
1287
1.33
1.80
3.6
3.8
0.0
0.0
estimate
0.00
38
207
8
30
2.71
1.73
3.5
1.8
34.3
33.6
pg
—
8
30
103
828
1.35
1.72
3.0
3.2
—
—
—
0
0
11
48
2.33
1.72
1.6
1.3
—
—
—
0
0
5
13
3.89
1.72
1.4
1.0
—
—
—
0
0
29
445
0.62
1.69
1.2
1.3
42.9
8.9
u/ml
0.75
12
164
31
463
0.64
1.61
1.2
1.3
57.2
38.3
iu/ml
0.39
13
151
16
283
0.54
1.60
2.3
1.5
—
—
—
0
0
7
26
2.73
1.59
2.3
1.8
—
—
—
0
0
205
1831
1.30
1.57
5.4
4.3
—
—
—
0
0
75
583
1.37
1.55
1.3
1.3
—
—
—
0
0
69
530
1.38
1.53
5.6
2.1
2.5
2.4
mmol/l
2.02
59
448
36
244
1.53
1.52
1.3
1.3
—
—
—
0
0
20
116
1.77
1.52
8.3
4.5
25.9
25.0
mmol/l
0.30
20
109
46
334
1.44
1.41
3.1
2.2
1.8
1.7
%
0.27
41
291
9
41
2.23
1.38
4.1
2.2
—
—
—
0
0
10
47
2.16
1.35
6.4
1.2
—
—
—
0
0
28
186
1.55
1.31
6.8
3.8
7.4
7.4
ph
—
5
20
5
18
2.80
1.29
2.0
1.3
—
—
—
0
0
27
179
1.55
1.28
3.7
1.3
—
—
—
0
0
298
2835
1.40
1.27
18.1
9.3
28.3
25.4
u/l
1.95
289
2708
13
70
1.89
1.25
4.7
1.2
19.4
33.6
mg/l
—
6
59
13
70
1.89
1.25
4.8
1.2
27.5
47.9
mg/l
—
6
58
230
2471
0.79
1.24
5.2
4.6
1.9
2.0
mu/l
0.60
213
2212
85
696
1.29
1.23
3.5
3.5
—
—
—
0
0
59
744
0.75
1.21
1.9
1.5
20.8
21.4
nmol/l
0.13
54
627
84
691
1.29
1.17
3.5
4.1
0.0
0.0
estimate
0.50
33
206
0
33
0.00
1.16
0.0
1.2
—
—
—
0
0
5
20
2.52
1.15
5.0
3.3
—
—
—
0
0
120
1033
1.25
1.15
3.3
3.6
—
—
—
0
0
129
1122
1.24
1.12
14.1
8.1
0.0
0.0
e9/l
0.72
112
926
10
51
1.99
1.12
6.3
2.7
—
—
—
0
0
108
1248
0.80
1.09
2.4
2.1
98.3
94.0
pmol/l
0.33
59
631
21
138
1.56
1.05
7.5
3.9
—
—
—
0
0
5
22
2.29
1.03
8.0
2.6
—
—
—
0
0
36
268
1.38
0.99
2.8
3.5
1.4
2.1
mmol/l
0.62
28
218
101
874
1.22
0.90
4.2
4.0
—
—
—
0
0
10
56
1.81
0.88
7.4
2.7
1.4
2.9
mmol/l
—
5
32
44
346
1.31
0.87
6.6
5.4
104.5
104.1
mmol/l
0.28
44
335
8
45
1.80
0.85
1.1
2.0
—
—
—
0
0
35
268
1.34
0.83
2.6
3.5
5.6
5.8
kpa
0.57
35
259
23
164
1.43
0.82
8.4
4.1
0.7
0.2
%
—
9
30
144
1300
1.19
0.81
4.9
5.2
0.0
0.0
estimate
0.00
36
202
5
96
0.51
0.79
1.0
1.1
—
—
—
0
0
24
174
1.41
0.79
7.9
4.0
0.0
0.1
%
0.80
11
38
0
26
0.00
0.78
0.0
2.0
—
—
—
0
0
0
26
0.00
0.78
0.0
1.2
—
—
—
0
0
0
27
0.00
0.77
0.0
1.0
—
282.2
—
0
20
16
107
1.52
0.77
17.6
12.8
—
—
—
0
0
25
184
1.39
0.76
8.0
3.9
0.5
0.7
%
0.18
11
41
128
1151
1.18
0.75
4.2
3.9
34.2
67.8
ng/l
0.60
96
851
145
1319
1.17
0.73
3.7
3.8
0.0
0.0
estimate
0.50
38
203
10
158
0.62
0.72
1.7
1.4
—
—
—
0
0
35
275
1.30
0.72
2.0
3.5
269.2
241.4
ng/l
0.10
29
254
83
722
1.20
0.70
3.3
2.4
5522.2
7629.8
umol/l
0.15
70
623
21
153
1.40
0.69
1.5
3.2
24.6
25.4
mmol/l
0.65
21
148
29
228
1.30
0.61
2.1
2.9
4.4
4.4
kpa
0.01
29
218
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
90.6
—
0
5
15
106
1.43
0.58
1.9
1.8
—
—
—
0
0
0
23
0.00
0.58
0.0
1.6
—
—
—
0
0
191
2019
0.88
0.56
4.5
3.7
15.0
15.0
pmol/l
0.19
176
1795
84
939
0.86
0.55
3.8
3.3
101.8
191.5
mg/l
0.41
63
582
18
134
1.36
0.54
13.5
12.9
—
—
—
0
0
87
962
0.87
0.49
3.7
3.2
7.4
7.6
mmol/l
0.09
73
790
63
555
1.17
0.48
1.9
1.8
1.2
1.2
mg/l
0.06
51
431
58
659
0.86
0.48
1.7
1.7
505.5
18267856.0
pmol/l
0.79
51
531
210
2193
0.89
0.46
25.5
18.3
331.1
332.1
g/l
0.85
205
2177
50
434
1.18
0.45
17.9
25.9
1.5
1.3
inr
—
7
65
5
31
1.62
0.43
2.0
3.3
—
—
—
0
0
21
167
1.27
0.43
8.0
4.1
0.0
0.0
%
0.49
11
34
8
57
1.41
0.42
1.8
1.9
—
—
—
0
0
5
32
1.57
0.42
3.0
1.5
92.1
90.2
%
—
5
32
84
920
0.88
0.41
2.4
2.1
239.3
221.4
u/l
0.07
78
853
68
610
1.14
0.41
4.0
4.0
539.6
280.6
ng/l
0.23
56
503
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
—
—
0
0
0
17
0.00
0.40
0.0
3.6
—
30.7
—
0
12
5
36
1.39
0.38
1.0
1.4
—
—
—
0
0
10
73
1.38
0.35
8.1
2.9
7.4
7.4
ph
—
10
55
10
73
1.38
0.35
7.4
3.3
—
—
—
0
0
6
45
1.34
0.34
1.5
1.6
312.8
270.4
mu/l
—
6
39
21
173
1.23
0.33
2.5
2.8
4.2
4.0
e9/l
0.18
15
121
76
697
1.12
0.33
2.3
2.2
3.3
3.0
mg/l
0.36
70
579
37
323
1.16
0.33
8.0
7.8
5.2
5.2
kpa
0.11
32
314
37
323
1.16
0.33
7.9
7.8
1.5
1.6
mmol/l
0.09
28
250
14
176
0.79
0.33
1.2
1.2
—
—
—
0
0
14
176
0.79
0.33
1.2
1.4
—
35.9
—
0
10
12
92
1.32
0.32
2.8
1.7
—
—
—
0
0
20
165
1.23
0.32
1.9
3.0
0.4
0.2
e6/l
0.32
20
159
60
545
1.12
0.31
8.9
4.0
—
—
—
0
0
7
96
0.72
0.31
4.4
3.5
4.0
3.9
mmol/l
—
7
88
7
53
1.33
0.31
2.3
2.4
—
—
—
0
0
30
260
1.17
0.30
1.5
1.5
—
—
—
0
0
93
994
0.91
0.30
4.4
4.0
19.0
6.9
mg/mmol
1.15
70
614
10
129
0.77
0.28
1.4
1.3
—
—
—
0
0
195
2016
0.92
0.28
4.8
4.2
16.1
12.5
mm/h
1.83
182
1825
37
329
1.14
0.27
1.4
1.3
1413.3
559.6
titre
—
6
93
24
206
1.18
0.27
1.9
1.5
—
—
—
0
0
8
67
1.20
0.26
2.8
2.2
8.2
7.8
kpa
—
8
59
226
2316
0.93
0.24
21.9
15.1
38.8
39.6
%
0.53
151
1526
287
2824
1.10
0.24
24.7
16.9
4.0
4.0
mmol/l
0.80
278
2743
286
2814
1.10
0.23
24.6
16.8
139.6
139.8
mmol/l
0.45
279
2732
5
38
1.32
0.23
1.2
1.1
—
—
—
0
0
5
38
1.32
0.23
1.2
1.1
—
—
—
0
0
5
38
1.32
0.23
3.2
3.9
262.0
360.6
umol/l
—
5
33
5
39
1.29
0.23
1.0
1.2
—
—
—
0
0
16
189
0.84
0.23
2.8
2.6
—
—
—
0
0
10
79
1.27
0.22
1.3
1.8
—
—
—
0
0
18
154
1.18
0.21
1.4
2.5
1.4
1.2
%
0.40
18
154
0
11
0.00
0.21
0.0
1.1
—
4.0
—
0
6
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
14
166
0.84
0.21
1.2
1.3
—
—
—
0
0
14
117
1.20
0.21
1.6
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
18
155
1.17
0.20
4.1
3.6
—
—
—
0
0
67
630
1.08
0.19
1.9
1.8
1219.5
1211.4
nmol/l
0.03
59
466
14
120
1.17
0.16
1.2
1.4
—
—
—
0
0
279
2754
1.07
0.16
19.7
13.0
—
—
—
0
0
6
77
0.78
0.15
1.2
1.1
—
—
—
0
0
295
2919
1.08
0.15
31.7
19.8
241.6
243.2
e9/l
0.13
287
2848
295
2919
1.08
0.15
31.5
19.8
30.3
30.4
pg
0.35
289
2870
295
2919
1.08
0.15
31.5
19.8
91.6
91.5
fl
0.25
289
2870
7
86
0.81
0.14
2.1
2.1
22.1
21.1
s
—
7
78
295
2920
1.07
0.14
31.7
19.9
7.3
6.7
e9/l
1.61
288
2838
295
2920
1.07
0.14
31.6
19.9
4.4
4.5
e12/l
2.11
287
2837
295
2921
1.07
0.14
31.8
20.0
132.2
136.0
g/l
3.98
290
2869
10
116
0.86
0.12
2.6
2.2
2068.6
311.9
ug/l
—
10
104
192
1952
0.96
0.11
4.0
4.0
—
—
—
0
0
19
208
0.91
0.10
1.4
1.5
—
—
—
0
0
5
60
0.83
0.08
1.0
1.2
—
—
—
0
0
5
65
0.77
0.08
1.0
2.8
—
—
—
0
0
59
610
0.96
0.07
3.4
2.7
0.7
0.8
ug/l
0.32
43
413
13
118
1.11
0.07
4.2
3.9
—
—
—
0
0
47
453
1.04
0.06
2.5
1.2
2.2
2.7
g/l
1.13
25
255
15
138
1.09
0.06
1.1
1.2
63.6
116.6
iu/ml
—
5
51
9
102
0.88
0.06
1.4
1.3
—
—
—
0
0
9
103
0.87
0.06
1.3
1.2
—
—
—
0
0
13
141
0.92
0.05
1.1
1.1
48.1
199.0
u/ml
2.96
13
132
36
374
0.96
0.05
1.3
1.2
—
—
—
0
0
10
91
1.10
0.04
6.0
4.1
—
—
—
0
0
15
160
0.93
0.04
2.0
2.4
—
—
—
0
0
24
231
1.04
0.03
9.2
6.0
1.6
1.4
mmol/l
0.31
24
222
111
1100
1.01
0.02
5.5
3.9
4.0
2.1
ug/l
0.52
99
972
22
213
1.04
0.01
11.3
7.3
—
—
—
0
0
51
517
0.98
0.01
1.3
1.2
0.4
1.4
u/ml
—
10
131
62
626
0.99
0.00
3.3
3.6
—
—
—
0
0
30
301
1.00
0.00
1.4
1.5
—
—
—
0
0
20
197
1.02
0.00
4.7
6.8
—
—
—
0
0
62
617
1.01
0.00
3.4
4.2
1.0
1.0
kg/l
0.03
11
104
23
234
0.98
0.00
6.3
3.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
13.7
—
0
5
5
53
0.94
0.00
2.2
2.4
106.0
105.1
mmol/l
—
5
53
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
17.8
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.5
—
51.3
—
0
8
5
52
0.96
0.00
2.2
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
67.0
—
0
6
8
88
0.91
0.00
1.8
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
5.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
5
53
0.94
0.00
2.2
2.4
4.1
4.1
mmol/l
—
5
53
5
57
0.88
0.00
1.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
10.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
5
53
0.94
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: CD2_UVEAMELANOMA_EXALLC – Melanoma of uvea

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).