This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Malignant neoplasm of nasal cavity and middle ear, excluding all cancers (controls excluding all cancers)
C3_NASAL_CAVITY_MIDDLE_EAR_EXALLC
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
246 |
4. Check minimum number of eventsNone |
246 |
5. Include endpointsNone |
246 |
6. Filter based on genotype QC (FinnGen only) |
246 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE_EXALLC
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of nasal cavity and middle ear, excluding all cancers (controls excluding all cancers)
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of nasal cavity and sinuses, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, wide definition for exclusion
- Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 246 | 106 | 140 |
| Unadjusted period prevalence (%) | 0.05 | 0.04 | 0.06 |
| Median age at first event (years) | 65.53 | 64.21 | 66.53 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 139
- Matched controls
- 1390
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C30.0
ICD-10 Finland
Malignant neoplasm: Nasal cavity
+∞
121.2
98
*
DHA10
NOMESCO Finland
Biopsy of cavity of nose
449.4
59.1
55
*
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
351.0
49.5
47
*
130
Kela drug reimbursment
Malignant tumour
+∞
48.9
44
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
26.9
45.8
66
45
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
45.3
41
*
8070/3-C30.0
ICD-O-3
Squamous cell carcinoma, NOS, of nasal cavity
+∞
45.3
41
*
DHB10
NOMESCO Finland
Excision of lesion of internal nose
+∞
41.8
38
*
WF002
NOMESCO Finland
Radical radiotherapy
468.6
36.8
35
*
H02AB02
ATC
dexamethasone; systemic
124.6
35.7
37
*
XX3DW
NOMESCO Finland
Time consuming IT work
38.2
34.1
43
16
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
30.3
28
*
A03FA01
ATC
metoclopramide; systemic, rectal
12.9
29.5
57
71
A04AA02
ATC
granisetron; systemic, transdermal
+∞
29.2
27
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
302.1
25.6
25
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
7.1
24.4
78
212
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
23.6
22
*
DM1DG
NOMESCO Finland
Paranasal sinuses and face area very extensive MRI examination with high intensity magnet
+∞
23.6
22
*
8720/3-C30.0
ICD-O-3
Malignant melanoma, NOS, of nasal cavity
+∞
23.6
22
*
A04AA01
ATC
ondansetron; systemic, rectal
43.3
23.1
28
8
UDM02
NOMESCO Finland
Sinoscopy
34.6
22.0
28
10
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
43.0
20.7
25
7
DNB30
NOMESCO Finland
Excision of lesion of ethmoidal sinus
+∞
20.3
19
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
20.3
19
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
19.2
18
*
R04.0
ICD-10 Finland
Epistaxis
9.1
18.4
41
61
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
18.1
17
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
18.1
17
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
205.1
18.0
18
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
32.3
17.1
22
8
D38.58
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of other respiratory organ
+∞
17.0
16
*
DJB10
NOMESCO Finland
Excision of septum of nose
+∞
17.0
16
*
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
192.1
16.9
17
*
N02AA05
ATC
oxycodone; systemic
7.4
16.3
42
77
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
22.7
16.2
23
12
Z51.5
ICD-10 Finland
Palliative care
25.8
16.1
22
10
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
15.9
15
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
+∞
15.9
15
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
14.3
15.4
26
22
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
19.8
14.9
22
13
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
41.0
14.8
18
5
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
166.8
14.8
15
*
L03AA02
ATC
filgrastim; parenteral
166.8
14.8
15
*
9522/3-C30.0
ICD-O-3
Olfactory neuroblastoma of nasal cavity
+∞
13.8
13
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
13.8
13
*
C72.2
ICD-10 Finland
Malignant neoplasm: Olfactory nerve
+∞
13.8
13
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
11.4
12.9
24
25
DPA30
NOMESCO Finland
Sphenotomy
77.1
12.8
14
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
12.7
12
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
12.7
12
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
12.7
12
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.1
11.9
55
190
SAA03
NOMESCO Finland
Extended examination of mouth
3.7
11.6
70
300
9680/3-C30.0
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of nasal cavity
+∞
11.6
11
*
DPC35
NOMESCO Finland
Extensive endoscopic excision of lesion or neoplasm extending to more than one paranasal sinus
+∞
11.6
11
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
+∞
11.6
11
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
11.6
11
*
DM1CG
NOMESCO Finland
Paranasal sinuses and face area extensive MRI examination with high intensity magnet
+∞
11.6
11
*
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
130.4
11.6
12
*
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
130.4
11.6
12
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
8.0
11.0
25
37
WX402
NOMESCO Finland
General anaesthesia
5.2
10.9
36
88
DHB40
NOMESCO Finland
Conchotomy
65.1
10.8
12
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
12.0
10.7
19
18
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
10.5
10
*
AAE99
NOMESCO Finland
Other operation by cranial base approach
+∞
10.5
10
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
10.5
10
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.2
9.7
73
357
ZXE30
NOMESCO Finland
More than five and less than seven hours
8.3
9.7
21
29
DMA00
NOMESCO Finland
Biopsy of maxillary antrum
107.0
9.5
10
*
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
107.0
9.5
10
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
9.5
9
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
9.5
9
*
EEB00
NOMESCO Finland
Partial excision of maxilla
+∞
9.5
9
*
A07AA02
ATC
nystatin; oral
6.7
9.1
23
40
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
5.1
9.0
29
68
C31.0
ICD-10 Finland
Malignant neoplasm: Maxillary sinus
+∞
8.4
8
*
DLW99
NOMESCO Finland
Other plastic operations on nose
+∞
8.4
8
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
8.4
8
*
D38.51
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of other accessory sinus
+∞
8.4
8
*
C31.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of accessory sinuses
+∞
8.4
8
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
8.4
8
*
R4190
NOMESCO Finland
Nutritional therapy
15.8
8.4
13
9
AA1BD
NOMESCO Finland
Extensive CT of head and brain
11.8
8.0
14
13
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
47.7
7.8
9
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.0
7.8
21
40
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
12.9
7.8
13
11
WW500
NOMESCO Finland
Blood transfusion
19.7
7.7
11
6
ZXC95
NOMESCO Finland
Use of surgical navigator
19.7
7.7
11
6
JN4BD
NOMESCO Finland
Extensive body CT
7.2
7.7
18
28
J34.8
ICD-10 Finland
Other specified disorders of nose and nasal sinuses
26.7
7.7
10
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.9
7.7
33
103
DMB30
NOMESCO Finland
Transmaxillary excision of lesion of maxillary antrum
84.4
7.5
8
*
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
84.4
7.5
8
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
84.4
7.5
8
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
7.4
7
*
C43.39
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face other or unspecified histology
+∞
7.4
7
*
A04AD12
ATC
aprepitant; systemic
+∞
7.4
7
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
+∞
7.4
7
*
DHB01
NOMESCO Finland
Partial excision of external nose
+∞
7.4
7
*
C03.0
ICD-10 Finland
Malignant neoplasm: Upper gum
+∞
7.4
7
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
7.4
7
*
L01CB01
ATC
etoposide; systemic
+∞
7.4
7
*
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
+∞
7.4
7
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
7.4
7
*
JN4AD
NOMESCO Finland
Body CT examination
9.0
7.0
14
17
DHB00
NOMESCO Finland
Excision of lesion of external nose
42.2
6.8
8
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
42.2
6.8
8
*
ZZR00
NOMESCO Finland
Flap of skin
23.9
6.8
9
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
5.9
6.7
18
34
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.6
6.6
75
436
TPH07
NOMESCO Finland
Cathetrisation of artery
4.5
6.6
23
59
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
8.8
6.5
13
16
UDC00
NOMESCO Finland
Ear microscopy
5.0
6.5
20
45
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
73.1
6.5
7
*
WZC30
NOMESCO Finland
Teaching
4.1
6.3
24
67
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
28.1
6.3
8
*
JN4CD
NOMESCO Finland
Very extensive body CT
28.1
6.3
8
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
+∞
6.3
6
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
6.3
6
*
ZZG00
NOMESCO Finland
Graft of cartilage
+∞
6.3
6
*
8020/3-C30.0
ICD-O-3
Carcinoma, undifferentiated, NOS, of nasal cavity
+∞
6.3
6
*
AAE05
NOMESCO Finland
Nasoendoscopic closure of cerebrospinal fluid fistula
+∞
6.3
6
*
8200/3-C30.0
ICD-O-3
Adenoid cystic carcinoma of nasal cavity
+∞
6.3
6
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
6.3
6
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
6.3
6
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
6.3
6
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
+∞
6.3
6
*
ZXA05
NOMESCO Finland
Left side
2.7
6.2
48
225
WX110
NOMESCO Finland
Local anesthesy
2.5
6.1
95
642
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
6.9
6.0
14
22
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_NASAL_CAVITY_MIDDLE_EAR_EXALLC – Malignant neoplasm of nasal cavity and middle ear, excluding all cancers (controls excluding all cancers)
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).