No definition available.
Malignant neoplasm of nasal cavity and sinuses, excluding all cancers (controls excluding all cancers)
C3_NASAL_CAVITY_SINUSES_EXALLC
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
359 |
4. Check minimum number of eventsNone |
359 |
5. Include endpointsNone |
359 |
6. Filter based on genotype QC (FinnGen only) |
359 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE_EXALLC
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of nasal cavity and sinuses, excluding all cancers (controls excluding all cancers)
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, wide definition for exclusion
- Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)
- Neoplasms
Similar with less cases:
- Malignant neoplasm of nasal cavity and middle ear, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of nasal cavity and sinuses
- Malignant neoplasm of accessory sinuses, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of nasal cavity and middle ear
- Malignant neoplasm of accessory sinuses
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 359 | 148 | 211 |
| Unadjusted period prevalence (%) | 0.08 | 0.05 | 0.09 |
| Median age at first event (years) | 65.70 | 63.79 | 67.04 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 207
- Matched controls
- 2068
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C30.0
ICD-10 Finland
Malignant neoplasm: Nasal cavity
+∞
126.4
108
*
130
Kela drug reimbursment
Malignant tumour
+∞
78.2
70
*
DHA10
NOMESCO Finland
Biopsy of cavity of nose
200.8
68.7
68
5
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
65.1
59
*
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
279.4
61.8
60
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
23.0
57.5
87
63
WF002
NOMESCO Finland
Radical radiotherapy
371.7
57.3
55
*
H02AB02
ATC
dexamethasone; systemic
78.4
48.1
53
9
8070/3-C30.0
ICD-O-3
Squamous cell carcinoma, NOS, of nasal cavity
+∞
44.4
41
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
43.3
40
*
DHB10
NOMESCO Finland
Excision of lesion of internal nose
+∞
43.3
40
*
A03FA01
ATC
metoclopramide; systemic, rectal
12.0
41.5
84
111
A04AA02
ATC
granisetron; systemic, transdermal
457.2
39.4
38
*
XX3DW
NOMESCO Finland
Time consuming IT work
20.2
37.8
58
39
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
223.7
37.1
37
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
35.4
33
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
7.0
35.2
113
302
C31.0
ICD-10 Finland
Malignant neoplasm: Maxillary sinus
+∞
34.3
32
*
DM1DG
NOMESCO Finland
Paranasal sinuses and face area very extensive MRI examination with high intensity magnet
394.1
33.9
33
*
UDM02
NOMESCO Finland
Sinoscopy
27.6
32.1
44
20
A04AA01
ATC
ondansetron; systemic, rectal
37.7
31.8
40
13
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
29.9
28
*
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
+∞
28.8
27
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
322.6
28.5
28
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
160.9
27.3
28
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
27.8
27.2
37
16
ZX090
NOMESCO Finland
Other technic of radiotherapy
295.5
26.3
26
*
L03AA02
ATC
filgrastim; parenteral
+∞
25.5
24
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
26.0
25.3
35
16
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
24.5
23
*
DNB30
NOMESCO Finland
Excision of lesion of ethmoidal sinus
+∞
24.5
23
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
269.8
24.2
24
*
R04.0
ICD-10 Finland
Epistaxis
9.1
23.9
53
75
D38.51
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of other accessory sinus
+∞
23.4
22
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
23.4
22
*
8720/3-C30.0
ICD-O-3
Malignant melanoma, NOS, of nasal cavity
+∞
23.4
22
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
22.8
23.0
33
17
N02AA05
ATC
oxycodone; systemic
6.7
22.7
64
129
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
22.3
21
*
Z51.5
ICD-10 Finland
Palliative care
27.8
21.5
29
12
C31.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of accessory sinuses
+∞
21.2
20
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
21.2
20
*
DJB10
NOMESCO Finland
Excision of septum of nose
+∞
20.1
19
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
20.1
19
*
DPA30
NOMESCO Finland
Sphenotomy
116.2
19.9
21
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
12.5
19.3
35
33
DMA00
NOMESCO Finland
Biopsy of maxillary antrum
+∞
19.0
18
*
8070/3-C31.0
ICD-O-3
Squamous cell carcinoma, NOS, of maxillary sinus
+∞
19.0
18
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
9.3
18.7
40
52
DM1CG
NOMESCO Finland
Paranasal sinuses and face area extensive MRI examination with high intensity magnet
+∞
18.0
17
*
DHB40
NOMESCO Finland
Conchotomy
196.0
17.8
18
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
196.0
17.8
18
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
12.8
17.4
31
28
SAA03
NOMESCO Finland
Extended examination of mouth
3.7
17.1
104
443
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
16.9
16
*
AAE99
NOMESCO Finland
Other operation by cranial base approach
+∞
16.9
16
*
EEB00
NOMESCO Finland
Partial excision of maxilla
+∞
16.9
16
*
D38.58
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of other respiratory organ
184.1
16.7
17
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.1
16.5
76
254
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
+∞
15.8
15
*
WX402
NOMESCO Finland
General anaesthesia
5.0
15.3
53
132
JN4BD
NOMESCO Finland
Extensive body CT
8.7
15.1
33
44
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
14.8
14
*
DPC35
NOMESCO Finland
Extensive endoscopic excision of lesion or neoplasm extending to more than one paranasal sinus
+∞
14.8
14
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.3
14.6
103
476
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
6.1
14.4
41
81
A07AA02
ATC
nystatin; oral
7.3
14.3
35
56
ZXC95
NOMESCO Finland
Use of surgical navigator
32.6
14.1
18
6
UDQ12
NOMESCO Finland
Flexible laryngoscopy
7.6
14.0
33
50
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
14.2
13.8
23
18
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
13.7
13
*
9522/3-C30.0
ICD-O-3
Olfactory neuroblastoma of nasal cavity
+∞
13.7
13
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
13.7
13
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
13.7
13
*
C72.2
ICD-10 Finland
Malignant neoplasm: Olfactory nerve
+∞
13.7
13
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
149.3
13.6
14
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
149.3
13.6
14
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
43.1
13.4
16
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
7.1
12.9
32
52
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
74.5
12.7
14
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
12.6
12
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
12.6
12
*
A04AD12
ATC
aprepitant; systemic
+∞
12.6
12
*
C03.0
ICD-10 Finland
Malignant neoplasm: Upper gum
+∞
12.6
12
*
DMB30
NOMESCO Finland
Transmaxillary excision of lesion of maxillary antrum
138.0
12.6
13
*
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
15.7
12.6
20
14
TPH07
NOMESCO Finland
Cathetrisation of artery
5.3
12.1
38
84
ZXE30
NOMESCO Finland
More than five and less than seven hours
8.1
11.7
26
36
WW500
NOMESCO Finland
Blood transfusion
12.9
11.6
20
17
C31.9
ICD-10 Finland
Malignant neoplasm: Accessory sinus, unspecified
+∞
11.6
11
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
11.6
11
*
9680/3-C30.0
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of nasal cavity
+∞
11.6
11
*
EEB10
NOMESCO Finland
Maxillectomy
+∞
11.6
11
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
11.6
11
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
15.0
11.2
18
13
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
45.9
11.0
13
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
19.1
10.9
16
9
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
63.3
10.7
12
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
63.3
10.7
12
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
115.6
10.5
11
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
10.5
10
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
+∞
10.5
10
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
10.5
10
*
D38.50
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of maxillary sinus
+∞
10.5
10
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
20.1
10.4
15
8
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
7.1
10.4
25
39
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
7.9
10.3
23
32
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.3
10.3
39
105
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
42.2
10.1
12
*
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
42.2
10.1
12
*
R4190
NOMESCO Finland
Nutritional therapy
11.5
10.0
18
17
WZC30
NOMESCO Finland
Teaching
4.4
9.7
36
95
ZZC00
NOMESCO Finland
Graft of fascia
+∞
9.4
9
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
9.4
9
*
ZZQ20
NOMESCO Finland
Free microvascular graft of skin, muscle and bone
+∞
9.4
9
*
C31.1
ICD-10 Finland
Malignant neoplasm: Ethmoidal sinus
+∞
9.4
9
*
C43.39
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face other or unspecified histology
+∞
9.4
9
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.2
9.3
36
99
SBB10
NOMESCO Finland
Teeth copy
6.0
9.3
25
46
D70.82
ICD-10 Finland
Drug-induced neutropenia
38.5
9.1
11
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.4
8.8
47
165
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
14.9
8.8
14
10
ZXE20
NOMESCO Finland
More than three and less than five hours
3.5
8.8
43
144
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
52.2
8.8
10
*
WX110
NOMESCO Finland
Local anesthesy
2.5
8.7
138
928
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
4.6
8.5
29
70
R01AD09
ATC
mometasone; nasal
2.4
8.5
96
541
DPB00
NOMESCO Finland
Partial excision of frontal sinus
93.7
8.5
9
*
J33.0
ICD-10 Finland
Polyp of nasal cavity
7.6
8.5
19
27
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
10.1
8.4
16
17
L01CB01
ATC
etoposide; systemic
+∞
8.4
8
*
AAE05
NOMESCO Finland
Nasoendoscopic closure of cerebrospinal fluid fistula
+∞
8.4
8
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
8.4
8
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
8.4
8
*
DLW99
NOMESCO Finland
Other plastic operations on nose
+∞
8.4
8
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
8.4
8
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
8.4
8
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
8.4
8
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
8.4
8
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
6.8
8.2
20
32
ZXE40
NOMESCO Finland
More than seven and less than nine hours
10.7
8.2
15
15
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
18.1
8.2
12
7
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
34.8
8.2
10
*
ZZR00
NOMESCO Finland
Flap of skin
23.1
8.1
11
5
GBB00
NOMESCO Finland
Tracheostomy
23.1
8.1
11
5
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.3
7.9
107
653
ZX120
NOMESCO Finland
Intravenous
4.8
7.7
25
58
J34.8
ICD-10 Finland
Other specified disorders of nose and nasal sinuses
26.1
7.6
10
*
AAK40
NOMESCO Finland
Closure of cerebrospinal fluid fistula
82.9
7.5
8
*
GD6AD
NOMESCO Finland
CT of chest and neck
82.9
7.5
8
*
DKW40
NOMESCO Finland
Ligature of artery of internal nose
82.9
7.5
8
*
EBA15
NOMESCO Finland
Extraction of large number of teeth
6.7
7.4
18
29
A04AA55
ATC
palonosetron, combinations; systemic
+∞
7.3
7
*
116
Kela drug reimbursment
Prostate cancer
+∞
7.3
7
*
QAB05
NOMESCO Finland
Revision of wound of skin of head or neck
+∞
7.3
7
*
A79
ICPC
Malignancy NOS
+∞
7.3
7
*
D36.7
ICD-10 Finland
Benign neoplasm: Other specified sites
+∞
7.3
7
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
7.3
7
*
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
+∞
7.3
7
*
ZZR50
NOMESCO Finland
Mucoperiosteal flap
+∞
7.3
7
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
7.3
7
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
7.3
7
*
DHB01
NOMESCO Finland
Partial excision of external nose
+∞
7.3
7
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
7.3
7
*
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
16.5
7.3
11
7
JN4AD
NOMESCO Finland
Body CT examination
8.4
7.2
15
19
SPF20
NOMESCO Finland
Temporary soling for filling
20.9
7.2
10
5
ZXA05
NOMESCO Finland
Left side
2.5
7.1
67
336
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.8
7.0
49
207
J33.9
ICD-10 Finland
Nasal polyp, unspecified
14.4
7.0
11
8
H16.0
ICD-10 Finland
Corneal ulcer
5.5
6.8
19
37
EBA10
NOMESCO Finland
Surgical removal of tooth
3.8
6.8
28
82
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
4.1
6.7
25
67
XW000
NOMESCO Finland
Bone marrow biopsy
7.3
6.6
15
22
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
6.1
6.6
17
30
TJD20
NOMESCO Finland
Change of gastrostomy tube
71.9
6.5
7
*
DKW99
NOMESCO Finland
Other procedures for control of epistaxis
71.9
6.5
7
*
ZZA00
NOMESCO Finland
Split skin graft
7.4
6.3
14
20
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
6.1
6.3
16
28
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
6.3
6
*
QAE20
NOMESCO Finland
Excision and repair of scar or web of skin of head or neck
+∞
6.3
6
*
DLD20
NOMESCO Finland
Rhinoplasty
+∞
6.3
6
*
8020/3-C30.0
ICD-O-3
Carcinoma, undifferentiated, NOS, of nasal cavity
+∞
6.3
6
*
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
+∞
6.3
6
*
CAD00
NOMESCO Finland
Exenteration of orbit with use of graft or flap
+∞
6.3
6
*
8200/3-C30.0
ICD-O-3
Adenoid cystic carcinoma of nasal cavity
+∞
6.3
6
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
6.3
6
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
6.3
6
*
L01AX03
ATC
temozolomide; systemic
+∞
6.3
6
*
ZXE60
NOMESCO Finland
More than 12 and less than 15 hours
27.6
6.3
8
*
DKW30
NOMESCO Finland
Cauterisation of artery of internal nose
27.6
6.3
8
*
DHB00
NOMESCO Finland
Excision of lesion of external nose
27.6
6.3
8
*
SAA04
NOMESCO Finland
Special inverstigation of mouth
4.5
6.2
21
51
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
13.0
6.1
10
8
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
9.0
6.1
12
14
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: C3_NASAL_CAVITY_SINUSES_EXALLC – Malignant neoplasm of nasal cavity and sinuses, excluding all cancers (controls excluding all cancers)
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).