info icon

This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_PENIS_EXALLC for full statistics.

Malignant neoplasm of penis

C3_PENIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only males

226837

2. Check conditions

None

226837

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C60
  • Cause of death: ICD-9 187[1-4]
  • Cause of death: ICD-8 1870
  • Cancer registry: Topography ICD-O-3 C60
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

116

4. Check minimum number of events

None

116

5. Include endpoints

None

116

6. Filter based on genotype QC (FinnGen only)

116

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 116 - 116
Unadjusted period prevalence (%) 0.05 - 0.05
Median age at first event (years) 65.60 - 65.60

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
112
Matched controls
1120
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C60.1
ICD-10 Finland
Malignant neoplasm: Glans penis
+∞
94.6
77
*
C60.9
ICD-10 Finland
Malignant neoplasm: Penis, unspecified
+∞
57.3
50
*
8070/3-C60.9
ICD-O-3
Squamous cell carcinoma, NOS, of penis, NOS
+∞
51.0
45
*
PJA12
NOMESCO Finland
Sentinel node biopsy
153.4
46.0
46
5
KGB00
NOMESCO Finland
Biopsy of penis
+∞
38.8
35
*
KGC00
NOMESCO Finland
Partial amputation of penis
+∞
38.8
35
*
8070/3-C60.1
ICD-O-3
Squamous cell carcinoma, NOS, of glans penis
+∞
37.6
34
*
C60.0
ICD-10 Finland
Malignant neoplasm: Prepuce
+∞
35.3
32
*
D40.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other male genital organs
424.3
32.6
31
*
PJD55
NOMESCO Finland
Block dissection of inguinal lymph nodes
+∞
30.6
28
*
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
40.0
28.9
36
13
KGD00
NOMESCO Finland
Partial excision of glans penis
+∞
23.8
22
*
KGD05
NOMESCO Finland
Partial excision of body of penis
+∞
22.7
21
*
KGH10
NOMESCO Finland
Operation for phimosis
19.8
21.6
33
23
N48.1
ICD-10 Finland
Balanoposthitis
25.5
20.9
29
15
C60.2
ICD-10 Finland
Malignant neoplasm: Body of penis
+∞
18.2
17
*
N47
ICD-10 Finland
Redundant prepuce, phimosis and paraphimosis
16.6
17.9
29
23
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
106.1
17.1
18
*
C60.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of penis
+∞
14.9
14
*
KGD96
NOMESCO Finland
Other partial excision of penis
171.3
14.8
15
*
C77.4
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Inguinal and lower limb lymph nodes
145.5
12.7
13
*
JN2AE
NOMESCO Finland
Ultrasound examination of lower part of abdomen without contrast
30.7
12.4
16
6
ZXE10
NOMESCO Finland
More than one and less than three hours
3.9
10.6
63
276
KDH10
NOMESCO Finland
Meatoplasty of urethra
+∞
10.6
10
*
WX402
NOMESCO Finland
General anaesthesia
5.2
10.5
36
94
TKD00
NOMESCO Finland
Dilatation of urethra
24.2
9.6
13
6
KGC10
NOMESCO Finland
Total amputation of penis
+∞
9.5
9
*
JN4BD
NOMESCO Finland
Extensive body CT
4.7
9.4
35
99
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
54.3
8.8
10
*
WX240
NOMESCO Finland
Penis blockade
97.0
8.5
9
*
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
97.0
8.5
9
*
D07.4
ICD-10 Finland
Carcinoma in situ: Penis
+∞
8.4
8
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
5.1
7.5
24
57
8051/3-C60.9
ICD-O-3
Verrucous carcinoma, NOS, of penis, NOS
+∞
7.4
7
*
D29.0
ICD-10 Finland
Benign neoplasm: Penis
+∞
7.4
7
*
N35.9
ICD-10 Finland
Urethral stricture, unspecified
18.1
6.9
10
6
KGD10
NOMESCO Finland
Destruction of lesion of penis
24.2
6.8
9
*
ZZA00
NOMESCO Finland
Split skin graft
8.2
6.6
14
19
UKC02
NOMESCO Finland
Cystoscopy
3.1
6.6
44
194
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
73.8
6.5
7
*
PJD54
NOMESCO Finland
Block dissection of iliac lymph nodes
19.3
6.4
9
5
N48.8
ICD-10 Finland
Other specified disorders of penis
28.4
6.3
8
*
N99.1
ICD-10 Finland
Postprocedural urethral stricture
+∞
6.3
6
*
8070/3-C60.0
ICD-O-3
Squamous cell carcinoma, NOS, of prepuce
+∞
6.3
6
*
JN4AD
NOMESCO Finland
Body CT examination
4.5
6.2
22
58
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
6.2
46
216
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
8.8
6.0
12
15

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_PENIS – Malignant neoplasm of penis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).