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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_TESTIS_EXALLC for full statistics.

Malignant neoplasm of testis

C3_TESTIS

testicular carcinoma: A primary or metastatic malignant neoplasm that affects the testis. Representative examples include seminoma, embryonal carcinoma, sarcoma, leukemia, and lymphoma.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only males

226837

2. Check conditions

None

226837

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C62
  • Cause of death: ICD-9 186
  • Cause of death: ICD-8 186
  • Cancer registry: Topography ICD-O-3 C62
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

613

4. Check minimum number of events

None

613

5. Include endpoints

None

613

6. Filter based on genotype QC (FinnGen only)

613

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 613 - 613
Unadjusted period prevalence (%) 0.27 - 0.27
Median age at first event (years) 36.23 - 36.23

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
566
Matched controls
5659
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
664.2
323.0
333
12
KFC00
NOMESCO Finland
Unilateral orchiectomy
1149.1
323.0
404
12
C62.11
ICD-10 Finland
Malignant tumor of the descending testicle, seminoma
+∞
268.8
236
*
9061/3-C62.9
ICD-O-3
Seminoma, NOS, of testis, NOS
+∞
245.2
217
*
C62.12
ICD-10 Finland
Malignant tumor of the descending testicle, embryonic carsinoma, teratocarcinoma or coriocarsinoma
+∞
160.2
146
*
JN4BD
NOMESCO Finland
Extensive body CT
15.4
127.8
231
242
C62.10
ICD-10 Finland
Malignant tumor of the descending testicle, no histological verification
+∞
98.9
92
*
130
Kela drug reimbursment
Malignant tumour
14.4
98.0
178
175
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
18.3
97.6
158
117
A03FA01
ATC
metoclopramide; systemic, rectal
9.7
94.9
220
348
C62.19
ICD-10 Finland
Malignant tumor of the descending testicle, other or undetermined histology
+∞
88.9
83
*
KFH50
NOMESCO Finland
Insertion of prosthetic replacement for testis
420.3
75.7
74
*
9085/3-C62.9
ICD-O-3
Mixed germ cell tumor of testis, NOS
+∞
73.6
69
*
C62.1
ICD-10 Finland
Malignant neoplasm: Descended testis
+∞
70.3
66
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
16.3
63.6
106
79
9061/3-C62.1
ICD-O-3
Seminoma, NOS, of descended testis
+∞
62.7
59
*
JN4AD
NOMESCO Finland
Body CT examination
10.9
61.6
125
143
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.4
59.1
334
1403
7511
FHL
Orchidectomy (unilateral), also includes funicularectomy
317.5
57.4
57
*
C62.99
ICD-10 Finland
Malignant tumor in unspecified location in testis,other or undetermined histology
556.6
52.3
51
*
C62.90
ICD-10 Finland
Malignant tumor in unspecified location in testis, no histological verification
532.5
50.2
49
*
9070/3-C62.9
ICD-O-3
Embryonal carcinoma, NOS, of testis, NOS
+∞
48.6
46
*
18699
ICD-8 Finland
Malignant neoplasm of testis
508.6
48.1
47
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
42.0
46.0
57
15
L03AA02
ATC
filgrastim; parenteral
22.2
45.7
67
34
A04AA02
ATC
granisetron; systemic, transdermal
12.8
45.3
83
75
121
Kela drug reimbursment
Severe hypofunction of sexual glands
27.3
36.5
50
20
C62.91
ICD-10 Finland
Malignant tumor in unspecified location in testis, seminoma
380.4
36.4
36
*
C62.00
ICD-10 Finland
Malignant tumor of the non-descending testicle, no histological verification
+∞
35.8
34
*
C62.92
ICD-10 Finland
Malignant tumor in unspecified location in testis, embryonic carsinoma, teratocarcinoma or coriocarsinoma
+∞
35.8
34
*
JN3AD
NOMESCO Finland
Abdominal CT examination
6.6
34.9
96
171
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.5
34.4
111
241
C62.01
ICD-10 Finland
Malignant tumor of the non-descending testicle, seminoma
+∞
33.7
32
*
PJD53
NOMESCO Finland
Block dissection of aortic lymph nodes
+∞
33.7
32
*
9680/3-C62.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of testis, NOS
+∞
32.6
31
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.1
32.4
242
1096
C62.02
ICD-10 Finland
Malignant tumor of the non-descending testicle, embryonic carsinoma, teratocarcinoma or coriocarsinoma
+∞
29.4
28
*
H02AB02
ATC
dexamethasone; systemic
6.3
28.8
81
147
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
26.3
26.9
37
15
9085/3-C62.1
ICD-O-3
Mixed germ cell tumor of descended testis
+∞
26.2
25
*
C62.9
ICD-10 Finland
Malignant neoplasm: Testis, unspecified
+∞
24.1
23
*
A04AA01
ATC
ondansetron; systemic, rectal
6.6
24.1
64
107
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
4.5
24.1
91
230
L03AA13
ATC
pegfilgrastim; parenteral
21.2
23.3
34
17
C62
ICD-10 Finland
Malignant neoplasm of testis
+∞
23.1
22
*
9081/3-C62.9
ICD-O-3
Teratocarcinoma of testis, NOS
+∞
23.1
22
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
20.0
22.9
34
18
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
47.1
22.5
27
6
ZXE00
NOMESCO Finland
One hour or less
2.5
21.4
234
1251
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
21.1
181
843
1869A
ICD-9 Finland
Malignant neoplasm of testis, Other and unspecified testis[NEOPL MAL TESTIS (SCROTALIS),SEMINOMA]
+∞
21.0
20
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
21.0
20.6
30
15
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
12.7
20.3
36
30
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
12.8
19.8
35
29
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.4
19.7
106
360
D29.2
ICD-10 Finland
Benign neoplasm: Testis
47.8
19.3
23
5
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
15.5
19.1
31
21
N02BE01
ATC
paracetamol; systemic, rectal
2.6
19.1
459
3545
E29.1
ICD-10 Finland
Testicular hypofunction
9.6
18.7
38
42
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
7.4
17.5
42
61
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
8.0
17.2
39
52
9080/3-C62.9
ICD-O-3
Teratoma, malignant, NOS, of testis, NOS
+∞
16.7
16
*
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
5.4
16.7
51
102
Y78
ICPC
Malign neopl male genital other
174.9
16.6
17
*
WX320
NOMESCO Finland
Spinalanesthesy
2.7
16.3
128
554
1869B
ICD-9 Finland
Malignant neoplasm of testis, Other and unspecified testis[NEOPL MAL TESTIS (SCROT),CA EMBR/TERATOCA/CHORIOCA]
+∞
15.7
15
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
15.3
196
1090
DFF00
NOMESCO Finland
Pure tone audiometry
3.7
14.2
65
194
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
20.7
13.9
20
10
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
7.2
13.3
32
47
N02AA05
ATC
oxycodone; systemic
3.0
12.8
80
297
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
71.5
12.6
14
*
N46
ICD-10 Finland
Male infertility
5.7
12.6
36
67
Z85.4
ICD-10 Finland
Personal history of malignant neoplasm of genital organs
+∞
12.5
12
*
E89.5
ICD-10 Finland
Postprocedural testicular hypofunction
132.8
12.5
13
*
Y05
ICPC
Scrotum/testis sympt/compl other
7.4
12.4
29
41
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.8
11.8
79
309
WX402
NOMESCO Finland
General anaesthesia
2.5
11.5
100
452
1869X
ICD-9 Finland
Malignant neoplasm of testis, Other and unspecified testis[NEOPL MAL TESTIS (SCROTALIS),EI HIST VAHV]
+∞
11.5
11
*
5703
FHL
Removal of lymph nodes from the retroperitoneal space
+∞
11.5
11
*
7513
FHL
Test prosthesis installation
122.4
11.5
12
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
11.4
189
1145
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
11.3
72
271
KFA00
NOMESCO Finland
Exploration of testis
11.5
11.1
20
18
JN4CD
NOMESCO Finland
Very extensive body CT
5.7
11.0
31
57
ZX120
NOMESCO Finland
Intravenous
3.2
10.8
58
197
WZC30
NOMESCO Finland
Teaching
2.6
10.8
80
333
B01AB05
ATC
enoxaparin; parenteral
2.1
10.7
133
710
9591/3-C62.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of testis, NOS
+∞
10.4
10
*
C62.0
ICD-10 Finland
Malignant neoplasm: Undescended testis
+∞
10.4
10
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
9.8
10.3
20
21
N05BA06
ATC
lorazepam; systemic, sublingual
4.2
10.1
38
96
WW500
NOMESCO Finland
Blood transfusion
5.1
9.9
30
61
KF8AE
SPAT
NA
7.3
9.6
22
31
A02BC02
ATC
pantoprazole; systemic
1.8
9.6
300
2217
C62.09
ICD-10 Finland
Malignant tumor of the non-descending testicle, other or undetermined histology
101.7
9.4
10
*
2395A
ICD-9 Finland
Neoplasm of unspecified nature, Other genito-urinary organs
101.7
9.4
10
*
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
8.2
9.4
20
25
9070/3-C62.1
ICD-O-3
Embryonal carcinoma, NOS, of descended testis
+∞
9.4
9
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
14.0
9.2
15
11
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
37.3
9.0
11
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
5.3
8.9
26
51
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
8.7
94
473
KFB00
NOMESCO Finland
Biopsy of testis
28.0
8.5
11
*
B01AB10
ATC
tinzaparin; parenteral
3.5
8.5
38
113
9063/3-C62.9
ICD-O-3
Spermatocytic seminoma of testis, NOS
+∞
8.4
8
*
L03AA14
ATC
lipegfilgrastim; parenteral
11.0
8.3
15
14
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
14.7
8.2
13
9
R50.9
ICD-10 Finland
Fever, unspecified
2.2
8.2
86
425
KA1FN
NOMESCO Finland
Isotope renography
17.5
8.1
12
7
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
22.4
8.0
11
5
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.7
8.0
34
97
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
4.3
8.0
28
67
XX3DW
NOMESCO Finland
Time consuming IT work
2.7
7.9
53
205
9071/3-C62.9
ICD-O-3
Yolk sac tumor, NOS, of testis, NOS
+∞
7.3
7
*
YJ1AD
NOMESCO Finland
CT examination of abdomen for dose design of radiotherapy
+∞
7.3
7
*
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
+∞
7.3
7
*
1860B
ICD-9 Finland
Malignant neoplasm of testis, Undescended testis[NEOP MAL TEST (ABD/ING),CA EMBR/TERATOCA/CHORIOCA]
+∞
7.3
7
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.8
7.2
46
175
M04AA01
ATC
allopurinol; systemic
2.3
7.2
69
327
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.1
7.2
37
123
N50.8
ICD-10 Finland
Other specified disorders of male genital organs
6.7
7.2
17
26
Y28
ICPC
Limited function/disability (Y)
12.2
7.1
12
10
A04AD12
ATC
aprepitant; systemic
9.5
6.8
13
14
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
6.6
105
612
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
4.9
6.6
20
42
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
8.8
6.6
13
15
KFD43
NOMESCO Finland
Unilateral vasectomy or ligature of vas deferens
70.6
6.4
7
*
JN4ED
NOMESCO Finland
Body CT examination with specail preparation
70.6
6.4
7
*
N02AX02
ATC
tramadol; systemic, rectal
1.6
6.4
198
1410
ZYY98
NOMESCO Finland
Missed treatment contact, no notification given by patient
18.3
6.3
9
5
KFC96
NOMESCO Finland
Other total excision of testis or epididymis
+∞
6.3
6
*

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_TESTIS – Malignant neoplasm of testis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).