No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF8
- Parent code in ICD-10
- C81-C96
- Name in latin
- Leuc(h)aemia monocytica
Similar endpoints
↥List of similar endpoints to
Monocytic leukaemia
based on the number of shared cases.
Similar with more cases:
- Monocytic leukaemia
- Primary_lymphoid and hematopoietic malignant neoplasms
- Primary_lymphoid and hematopoietic malignant neoplasms
- Malignant neoplasm
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 111 | 47 | 64 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 65.71 | 60.56 | 69.49 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 101
- Matched controls
- 1011
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
396.6
60.3
55
*
C93.1
ICD-10 Finland
Chronic myelomonocytic leukaemia
+∞
46.5
41
*
C93.0
ICD-10 Finland
Acute monoblastic/monocytic leukaemia
+∞
36.7
33
*
XW000
NOMESCO Finland
Bone marrow biopsy
41.3
31.5
39
15
WW500
NOMESCO Finland
Blood transfusion
100.2
27.5
29
*
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
294.0
23.7
23
*
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
+∞
21.6
20
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
21.6
20
*
A04AA01
ATC
ondansetron; systemic, rectal
55.3
19.1
22
5
D64.9
ICD-10 Finland
Anaemia, unspecified
9.7
16.1
35
52
Z51.5
ICD-10 Finland
Palliative care
20.0
14.2
21
13
R50.9
ICD-10 Finland
Fever, unspecified
7.0
13.0
35
71
L03AA02
ATC
filgrastim; parenteral
+∞
12.8
12
*
M04AA01
ATC
allopurinol; systemic
6.3
12.0
35
78
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
134.7
11.7
12
*
C93.9
ICD-10 Finland
Monocytic leukaemia, unspecified
+∞
11.7
11
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
24.8
11.1
15
7
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.3
10.9
31
66
B03XA02
ATC
darbepoetin alfa; parenteral
122.2
10.6
11
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.8
10.0
30
68
L01XX05
ATC
hydroxycarbamide; oral
30.5
8.7
11
*
9860/3-C42.1
ICD-O-3
Myeloid leukemia, NOS, of bone marrow
+∞
8.4
8
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
8.4
8
*
9891/3-C42.1
ICD-O-3
Acute monocytic leukemia of bone marrow
+∞
8.4
8
*
JN4BD
NOMESCO Finland
Extensive body CT
10.8
8.1
15
16
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
86.1
7.5
8
*
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
86.1
7.5
8
*
J05AB11
ATC
valaciclovir; oral
4.9
7.5
25
63
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
7.4
7
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.4
7
*
A41.9
ICD-10 Finland
Sepsis, unspecified
9.1
6.6
13
16
A03FA01
ATC
metoclopramide; systemic, rectal
5.2
6.5
20
46
127
Kela drug reimbursment
Transplant complication
28.7
6.3
8
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
6.3
6
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
6.3
6
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
6.3
6
*
J01MA12
ATC
levofloxacin; systemic
3.5
6.3
31
112
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: CD2_MONOCYTIC_LEUKAEMIA_EXALLC – Monocytic leukaemia
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).