This is a non-core endpoint: only basic statistics are computed.
See its core counterpart CD2_MULTIPLE_MYELOMA_PLASMA_CELL_EXALLC for full statistics.
Multiple myeloma and malignant plasma cell neoplasms
CD2_MULTIPLE_MYELOMA_PLASMA_CELL
multiple myeloma: A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1646 |
4. Check minimum number of eventsNone |
1646 |
5. Include endpointsNone |
1646 |
6. Filter based on genotype QC (FinnGen only) |
1646 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF8
- Parent code in ICD-10
- C81-C96
- Name in latin
- Myeloma multiplex et neoplasmata maligna plasmacytorum
Similar endpoints
↥List of similar endpoints to
Multiple myeloma and malignant plasma cell neoplasms
based on the number of shared cases.
Similar with more cases:
- Multiple myeloma and malignant plasma cell neoplasms
- Primary_lymphoid and hematopoietic malignant neoplasms
- Primary_lymphoid and hematopoietic malignant neoplasms
- Malignant neoplasm
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1646 | 722 | 924 |
| Unadjusted period prevalence (%) | 0.34 | 0.25 | 0.41 |
| Median age at first event (years) | 69.18 | 68.21 | 69.95 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1545
- Matched controls
- 15448
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
113.4
323.0
1074
304
C90.0
ICD-10 Finland
Multiple myeloma
4503599627370496.0
323.0
1384
*
L04AX04
ATC
lenalidomide; oral
+∞
323.0
559
*
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
7179.8
323.0
784
*
329
Kela drug reimbursment
Lenalidomide
+∞
323.0
378
*
H02AB02
ATC
dexamethasone; systemic
21.2
323.0
852
846
XW000
NOMESCO Finland
Bone marrow biopsy
45.9
323.0
737
301
153
Kela drug reimbursment
Lenalidomid
+∞
323.0
607
*
L03AA02
ATC
filgrastim; parenteral
43.5
323.0
449
144
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
537.0
316.9
305
7
WW300
NOMESCO Finland
Transfer of autologic stem cells
540.1
279.5
270
6
M04AA01
ATC
allopurinol; systemic
8.4
271.4
735
1505
A04AA01
ATC
ondansetron; systemic, rectal
14.1
264.7
489
491
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
14.5
258.7
470
452
AA1AA
NOMESCO Finland
Head X-ray examination
79.5
241.0
270
41
J05AB01
ATC
aciclovir; systemic
6.7
225.1
730
1823
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
45.2
213.6
264
70
L01AA03
ATC
melphalan; systemic
+∞
208.1
195
*
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
161.9
190.5
198
14
ZX112
NOMESCO Finland
Subcutaneous
26.2
189.6
269
123
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
18.8
183.6
292
189
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
21.5
179.8
272
152
WX2DD
NOMESCO Finland
Low-dose CT of skeleton in whole body
392.6
178.4
176
5
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.6
168.1
931
3859
N02AA05
ATC
oxycodone; systemic
5.4
165.0
613
1667
ZX120
NOMESCO Finland
Intravenous
6.7
144.9
417
806
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
35.0
137.7
180
58
C90.2
ICD-10 Finland
Extramedullary plasmacytoma
+∞
135.4
128
*
393
Kela drug reimbursment
Pomalidomide
+∞
131.1
124
*
J05AB11
ATC
valaciclovir; oral
5.6
130.5
443
1039
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
27.6
130.1
181
74
YNB10
NOMESCO Finland
Collection of stem cells for transplant
671.2
127.3
124
*
WW500
NOMESCO Finland
Blood transfusion
9.9
126.8
271
324
B03XA02
ATC
darbepoetin alfa; parenteral
17.9
123.3
198
126
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
12.3
120.7
229
216
1507
Kela drug reimbursment
Pomalidomide
+∞
118.3
112
*
R50.9
ICD-10 Finland
Fever, unspecified
4.8
117.5
466
1278
1XX32
NOMESCO Finland
NA
1205.1
116.2
112
*
M05BA02
ATC
clodronic acid; systemic
77.9
114.4
129
18
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
143.1
112.8
119
9
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.9
112.2
429
1125
L04AX06
ATC
pomalidomide; oral
+∞
111.8
106
*
WW409
NOMESCO Finland
Other aferesis
202.9
110.0
113
6
WW402
NOMESCO Finland
Leucoferesis
1078.2
104.5
101
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.0
103.6
278
469
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
31.4
103.0
138
48
NE1AA
NOMESCO Finland
Pelvis X-ray examination
5.9
102.4
319
655
WF049
NOMESCO Finland
Radiotherapy of metastasis
9.4
101.6
222
271
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
5.1
100.6
361
872
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
8.8
99.4
227
298
M90.7*C90.0
ICD-10 Finland
Pathological fracture in multiple myeloma
+∞
99.0
94
*
ZX108
NOMESCO Finland
Inhalation
46.8
98.8
121
28
L04AX02
ATC
thalidomide; oral
908.3
88.6
86
*
WW200
NOMESCO Finland
Immunization
11.4
81.3
158
153
398
Kela drug reimbursment
Ixazomib
+∞
80.9
77
*
212
Kela drug reimbursment
Gout
10.3
77.1
158
169
1505
Kela drug reimbursment
Ixazomib
+∞
75.6
72
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.7
75.4
930
5535
B03XA01
ATC
erythropoietin; parenteral
22.7
75.1
110
52
B01AB05
ATC
enoxaparin; parenteral
2.8
74.5
697
3507
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.9
73.2
617
2899
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
13.0
67.9
123
102
D64.9
ICD-10 Finland
Anaemia, unspecified
3.7
67.3
335
1066
C90.1
ICD-10 Finland
Plasma cell leukaemia
+∞
67.2
64
*
L01AA01
ATC
cyclophosphamide; systemic
34.5
65.3
85
26
5BA08
NOMESCO Finland
NA
42.1
64.2
80
20
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
7.7
61.3
149
211
JN4AD
NOMESCO Finland
Body CT examination
4.2
60.9
253
681
J01MA12
ATC
levofloxacin; systemic
2.9
60.7
471
2049
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.5
60.7
191
383
M49.5*C90.0
ICD-10 Finland
Vertebral fracture due to multiple myeloma
+∞
58.7
56
*
B74
ICPC
Malignant neoplasm blood other
129.1
58.3
62
5
Z52.89
ICD-10 Finland
Donor of other organ or tissue
189.9
53.3
55
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
5.5
53.0
168
338
C03CA01
ATC
furosemide; systemic
2.4
53.0
691
3946
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
52.0
398
1691
A02BC02
ATC
pantoprazole; systemic
2.4
51.8
1124
8174
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.4
49.9
602
3281
TK800
NOMESCO Finland
Hemodialysis
8.5
48.7
110
138
J01MA14
ATC
moxifloxacin; systemic
3.6
48.7
242
753
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
17.0
48.6
78
48
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
11.4
47.2
90
83
M05BX04
ATC
denosumab; parenteral
4.6
46.4
172
409
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
8.0
46.3
108
143
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
45.7
316
1245
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
28.0
45.4
62
23
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.3
45.3
146
298
GA5AA
NOMESCO Finland
Rib X-ray examination
35.4
45.0
58
17
L01XX50
ATC
[U] ixazomib; oral
+∞
45.0
43
*
C90
ICD-10 Finland
Multiple myeloma and malignant plasma cell neoplasms
+∞
45.0
43
*
1CX01
NOMESCO Finland
NA
450.1
44.4
44
*
WF004
NOMESCO Finland
Palliative radiotherapy
8.2
44.3
102
132
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
16.5
43.8
71
45
B01AB10
ATC
tinzaparin; parenteral
3.9
43.3
191
534
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.8
41.6
146
327
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
39.1
436
2226
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
9.3
39.1
83
94
N08.1*C90.0
ICD-10 Finland
Glomerular disorders in multiple myeloma
+∞
38.7
37
*
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
51.4
37.7
45
9
NB6AA
NOMESCO Finland
Humerus X-ray examination
7.1
36.3
91
134
A41.9
ICD-10 Finland
Sepsis, unspecified
4.8
36.1
126
280
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.8
34.2
156
447
M84.4
ICD-10 Finland
Pathological fracture, not elsewhere classified
36.8
33.8
43
12
A05AA02
ATC
ursodeoxycholic acid; oral
11.3
33.6
64
59
E83.50
ICD-10 Finland
Hypercalcemia
10.0
33.0
67
70
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
9.7
32.0
66
71
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
24.3
31.9
45
19
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
22.5
31.9
46
21
Z51.5
ICD-10 Finland
Palliative care
3.2
31.6
176
588
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
31.6
630
4043
L01XG03
ATC
ixazomib; oral
+∞
31.3
30
*
A03FA01
ATC
metoclopramide; systemic, rectal
2.2
31.3
381
1994
127
Kela drug reimbursment
Transplant complication
8.5
31.2
69
84
WX1BG
NOMESCO Finland
Total body MRI with high intensity magnet
163.2
30.8
32
*
M90.7
ICD-10 Finland
Fracture of bone in neoplastic disease
+∞
30.3
29
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.7
29.9
221
890
D70.89
ICD-10 Finland
Neutropenic splenomegaly
11.8
29.7
55
48
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
22.1
29.7
43
20
WX1CG
NOMESCO Finland
Extensive total body MRI with high intensity magnet
+∞
29.3
28
*
NF3AA
NOMESCO Finland
Femur X-ray examination
6.3
28.6
78
130
N16.1*C90.0
ICD-10 Finland
Renal tubulo-interstitial disorders in multiple myeloma
+∞
28.2
27
*
2030A
ICD-9 Finland
Multiple myeloma and immunoproliferative neoplasms, Multiple myeloma
+∞
28.2
27
*
5BA03
NOMESCO Finland
NA
+∞
28.2
27
*
A06AD11
ATC
lactulose; oral
2.2
27.9
338
1754
E85.89
ICD-10 Finland
Other amyloidosis
147.6
27.7
29
*
H02AB06
ATC
prednisolone; systemic
1.8
27.3
776
5535
JN4BD
NOMESCO Finland
Extensive body CT
2.4
27.0
255
1173
YN7AD
NOMESCO Finland
CT examination of spine for dose design of radiotherapy
20.5
27.0
40
20
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
3.3
25.9
139
452
E85.9
ICD-10 Finland
Amyloidosis, unspecified
20.5
25.7
38
19
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
5.7
25.4
74
134
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
18.2
25.3
39
22
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
25.2
228
1023
XX3DW
NOMESCO Finland
Time consuming IT work
2.5
25.1
224
997
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
59.0
25.1
29
5
1AA01
NOMESCO Finland
NA
71.1
24.9
28
*
WX1DG
NOMESCO Finland
Very extensive total body MRI with high intensity magnet
254.0
24.7
25
*
H02AB09
ATC
hydrocortisone; systemic
5.6
24.5
73
136
N03AX16
ATC
pregabalin; oral
1.9
23.8
416
2483
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
5.4
23.8
73
141
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
23.7
723
5188
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
5.1
23.5
76
156
NBJ60
NOMESCO Finland
Internal fixation of fracture of shoulder or upper arm using intramedullary nail, humerus
33.9
23.4
30
9
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
12.3
23.3
42
35
ZX090
NOMESCO Finland
Other technic of radiotherapy
4.4
23.2
86
204
ZXD05
NOMESCO Finland
Urgent procedure
1.8
22.9
508
3286
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
9.5
22.9
47
51
NB4AA
NOMESCO Finland
Scapula X-ray examination
26.3
22.7
31
12
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
22.7
503
3251
M49.5
ICD-10 Finland
Collapsed vertebra in diseases classified elsewhere
233.2
22.7
23
*
306
Kela drug reimbursment
Erythropoietin and darbepoetin
23.3
22.6
32
14
G62.0
ICD-10 Finland
Drug-induced polyneuropathy
27.8
22.3
30
11
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
7.4
22.1
53
74
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
4.1
21.5
87
224
L03AA13
ATC
pegfilgrastim; parenteral
3.9
21.5
91
244
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.7
21.4
152
594
N02AX02
ATC
tramadol; systemic, rectal
1.7
21.2
686
4952
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.4
21.1
197
893
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.2
21.1
81
199
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.6
20.8
97
283
N18.8
ICD-10 Finland
Other chronic renal failure
4.0
20.7
86
227
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.4
20.3
194
889
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
6.8
19.8
50
76
A11CC03
ATC
alfacalcidol; systemic
4.4
19.4
72
171
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.5
19.3
156
654
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.6
19.2
67
150
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.7
19.1
135
523
3XA02
NOMESCO Finland
NA
55.7
18.9
22
*
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
4.2
18.9
73
181
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
6.7
18.8
48
74
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
18.6
394
2476
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
192.2
18.6
19
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
8.2
18.5
41
51
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.9
18.5
77
204
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
5.3
18.4
56
108
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
18.4
505
3438
NFJ60
NOMESCO Finland
Internal fixation of fracture of other parts of femur with intramedullary nail
12.0
18.3
33
28
L03AB05
ATC
interferon alfa-2b; parenteral
17.8
18.3
28
16
N17.8
ICD-10 Finland
Other acute renal failure
7.0
18.0
44
64
M36.1*C90.0
ICD-10 Finland
Arthropathy in multiple myeloma
+∞
17.7
17
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
4.4
17.7
64
149
EBA10
NOMESCO Finland
Surgical removal of tooth
2.4
16.8
147
645
I43.1*E85.9
ICD-10 Finland
Cardiac amyloidosis
64.0
16.8
19
*
M82.0*C90.0
ICD-10 Finland
Osteoporosis in multiple myelomatosis
+∞
16.7
16
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
16.6
244
1344
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.2
16.6
51
100
NA2AD
NOMESCO Finland
Thoracic spine CT examination
10.2
16.4
32
32
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
20.3
16.4
24
12
L04AD01
ATC
ciclosporin; systemic
5.0
16.2
52
107
M49.5*C79.5
ICD-10 Finland
Metastatic fracture of vertebra
30.4
16.1
21
7
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.7
16.1
70
194
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
33.7
15.7
20
6
6BA02
NOMESCO Finland
NA
17.4
15.6
24
14
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
5.8
15.6
44
78
L01BB05
ATC
fludarabine; systemic
26.6
15.6
21
8
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
8.6
15.5
33
39
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
15.4
318
1969
N05CF01
ATC
zopiclone; oral
1.6
15.4
538
3866
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
14.9
15.4
25
17
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.5
15.3
122
507
D70.82
ICD-10 Finland
Drug-induced neutropenia
5.3
14.9
45
87
A07AA02
ATC
nystatin; oral
2.4
14.8
132
584
B73
ICPC
Leukaemia
32.0
14.8
19
6
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
57.2
14.8
17
*
N08.1
ICD-10 Finland
Glomerular disorders in neoplastic diseases
+∞
14.6
14
*
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
14.3
14.5
24
17
A79
ICPC
Malignancy NOS
5.4
14.4
43
82
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
27.4
14.3
19
7
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
14.2
147
698
N08.4*E85.9
ICD-10 Finland
Glomerular disorders in amyloidosis
53.8
13.8
16
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
13.8
165
837
WZC30
NOMESCO Finland
Teaching
1.9
13.7
218
1233
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
6.2
13.7
36
59
N19
ICD-10 Finland
Unspecified kidney failure
2.8
13.7
88
324
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
13.6
314
2003
L71
ICPC
Malignant neoplasm musculoskeletal
75.8
13.6
15
*
9731/3-C42.1
ICD-O-3
Plasmacytoma, NOS, of bone marrow
+∞
13.6
13
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
13.4
477
3416
H02AB07
ATC
prednisone; oral
1.8
13.2
240
1419
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
13.0
266
1635
R80
ICD-10 Finland
Isolated proteinuria
9.4
13.0
26
28
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
50.4
12.8
15
*
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
7.3
12.8
30
42
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.2
12.8
66
211
B02.9
ICD-10 Finland
Zoster without complication
2.4
12.7
112
492
NB4DA
NOMESCO Finland
Bilateral scapula X-ray examination
+∞
12.5
12
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
5.9
12.4
34
59
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
3.0
12.3
71
244
Z3231
NOMESCO Finland
Registered nurse
1.6
12.3
419
2961
J02AC03
ATC
voriconazole; systemic
16.0
12.1
19
12
SPAT1088
SPAT
Blood transfusion
8.2
12.1
26
32
SPAT1255
SPAT
Intravenous administration of medicine
2.2
12.0
125
594
GD1AD
NOMESCO Finland
Thorax CT examination
2.6
12.0
90
365
ZXE00
NOMESCO Finland
One hour or less
1.5
11.9
570
4338
ZX080
NOMESCO Finland
Image guided radiotherapy
3.8
11.9
50
136
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
3.8
11.9
49
131
TGC00
NOMESCO Finland
Bronchial lavation
3.3
11.8
59
184
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
8.4
11.8
25
30
H02AB04
ATC
methylprednisolone; systemic
1.8
11.8
227
1366
ZY010
NOMESCO Finland
Hospital outpatient
3.1
11.7
65
219
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
16.5
11.7
18
11
A02BC01
ATC
omeprazole; systemic
1.5
11.6
437
3151
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
12.6
11.6
20
16
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
19.1
11.6
17
9
20399
ICD-8 Finland
Multiple myeloma
+∞
11.5
11
*
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
13.7
11.5
19
14
N05BA06
ATC
lorazepam; systemic, sublingual
2.4
11.4
98
426
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.3
11.4
106
479
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
11.4
248
1550
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
4.1
11.3
43
107
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
6.3
11.2
29
47
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.6
11.1
78
304
L01AA02
ATC
chlorambucil; oral
11.2
11.0
20
18
A41.8
ICD-10 Finland
Other specified sepsis
4.0
11.0
43
110
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
7.5
11.0
25
34
A06AH03
ATC
naloxegol; oral
4.9
10.8
34
70
N02BE01
ATC
paracetamol; systemic, rectal
1.6
10.7
1263
11457
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
17.9
10.7
16
9
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.1
10.6
40
99
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.2
10.6
55
177
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
14.3
10.5
17
12
ZYC01
NOMESCO Finland
Remote contact by phone
2.7
10.4
70
267
JN4CD
NOMESCO Finland
Very extensive body CT
2.5
10.4
81
337
J01CA04
ATC
amoxicillin; systemic
1.5
10.3
1093
9634
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.5
10.3
47
138
YN1BD
NOMESCO Finland
Extensive CT examination of extremities for dose design of radiotherapy
23.5
10.2
14
6
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
7.5
10.2
23
31
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.4
10.1
47
140
A28
ICPC
Limited function/disability NOS
1.6
10.1
277
1841
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
4.5
10.0
34
77
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
3.2
9.9
51
164
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
6.8
9.9
24
36
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.0
9.9
125
648
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
8.8
9.8
20
23
A40.8
ICD-10 Finland
Other streptococcal sepsis
4.5
9.8
33
74
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
6.6
9.7
24
37
N18.0
ICD-10 Finland
End-stage renal disease
4.5
9.7
33
75
WF099
NOMESCO Finland
Other radiotherapy
6.0
9.5
25
42
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
4.8
9.5
30
63
3AA13
NOMESCO Finland
NA
17.6
9.4
14
8
9731/3-C41.3
ICD-O-3
Plasmacytoma, NOS, of rib, sternum, clavicle and associated joints
+∞
9.4
9
*
1XX45
NOMESCO Finland
NA
+∞
9.4
9
*
ZXF99
NOMESCO Finland
Other r3eason to interrupt procedure
8.1
9.3
20
25
WX110
NOMESCO Finland
Local anesthesy
1.4
9.2
880
7520
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.0
9.2
50
168
I80.1
ICD-10 Finland
Phlebitis and thrombophlebitis of femoral vein
4.0
9.1
35
89
H26.3
ICD-10 Finland
Drug-induced cataract
7.8
9.1
20
26
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
5.0
9.1
28
57
M80.8
ICD-10 Finland
Other osteoporosis with pathological fracture
9.1
9.0
18
20
YNB00
NOMESCO Finland
Excision of bone marrow for transplantation
36.9
9.0
11
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.0
9.0
51
174
ECB20
NOMESCO Finland
Oral alveoplasty
5.8
8.9
24
42
C88.0
ICD-10 Finland
Waldenström macroglobulinaemia
12.6
8.9
15
12
M48.5
ICD-10 Finland
Collapsed vertebra, not elsewhere classified
8.7
8.8
18
21
B99
ICPC
Blood/lymph/spleen disease other
10.8
8.8
16
15
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
9.5
8.8
17
18
A07AA09
ATC
vancomycin; oral
3.9
8.7
34
88
1XC02
NOMESCO Finland
NA
5.8
8.6
23
40
L01BB02
ATC
mercaptopurine; oral
8.3
8.6
18
22
L03AA04
ATC
NA
16.4
8.6
13
8
A12AA04
ATC
calcium carbonate; oral
3.4
8.5
39
116
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.0
8.5
105
541
372
Kela drug reimbursment
Idelalisib
27.7
8.5
11
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
3.8
8.4
34
91
M54.5
ICD-10 Finland
Low back pain
1.4
8.4
408
3071
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
8.4
88
421
R06.0
ICD-10 Finland
Dyspnoea
1.5
8.4
375
2777
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
8.4
303
2143
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
7.9
8.4
18
23
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
7.9
8.4
18
23
9731/3-C41.2
ICD-O-3
Plasmacytoma, NOS, of vertebral column
+∞
8.3
8
*
NAR00
NOMESCO Finland
Complete excision of tumour of bone or cartilage of spine, unspecified
+∞
8.3
8
*
ED1AA
NOMESCO Finland
Mandipular X-ray examination
6.2
8.3
21
34
ZX070
NOMESCO Finland
Intensity modified radiotherapy
3.1
8.3
44
146
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
10.8
8.3
15
14
WVA20
NOMESCO Finland
Medicine administration
3.1
8.3
43
141
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
7.1
8.3
19
27
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.1
8.2
88
428
L01XE27
ATC
[U] ibrutinib; oral
14.5
8.2
13
9
WX892
NOMESCO Finland
Monitored bed care
1.9
8.2
120
656
R4110
NOMESCO Finland
Physiotherapy
1.4
8.1
383
2863
S42.3
ICD-10 Finland
Fracture of shaft of humerus
4.2
8.1
29
70
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
8.1
245
1664
L01XX47
ATC
[U] idelalisib; oral
33.5
8.1
10
*
E85.3
ICD-10 Finland
Secondary systemic amyloidosis
17.3
8.1
12
7
390
Kela drug reimbursment
Ibrutinib
11.8
8.1
14
12
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
9.0
8.0
16
18
C96.9
ICD-10 Finland
Malignant neoplasm of lymphoid, haematopoietic and related tissue, unspecified
22.1
8.0
11
5
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.0
7.9
98
503
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
7.9
148
880
J01DB01
ATC
cefalexin; oral
1.4
7.9
1134
10249
NF1AA
NOMESCO Finland
Hip X-ray examination
1.7
7.9
151
904
UJF30
NOMESCO Finland
Ileoscopy through colon
1.8
7.9
132
758
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
7.8
206
1350
D64.8
ICD-10 Finland
Other specified anaemias
3.4
7.8
36
108
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.3
7.8
70
314
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
4.7
7.8
25
54
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
7.8
264
1839
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
10.9
7.8
14
13
WF002
NOMESCO Finland
Radical radiotherapy
2.1
7.8
88
436
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
4.6
7.7
25
55
N03AX12
ATC
gabapentin; oral
1.6
7.6
216
1443
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.5
7.6
326
2384
B00.2
ICD-10 Finland
Herpesviral gingivostomatitis and pharyngotonsillitis
11.9
7.6
13
11
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
7.6
239
1637
J20.4
ICD-10 Finland
Acute bronchitis due to parainfluenza virus
80.4
7.4
8
*
L04AA06
ATC
mycophenolic acid; systemic
3.5
7.4
33
97
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.3
7.4
21
40
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.8
7.3
115
648
1512
Kela drug reimbursment
Ibrutinib
10.9
7.3
13
12
GA5DA
NOMESCO Finland
Bilateral rib X-ray exmaination
+∞
7.3
7
*
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
4.5
7.3
24
54
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.9
7.3
99
529
V03AE01
ATC
polystyrene sulfonate; oral
3.7
7.2
29
79
L01XX52
ATC
venetoclax; oral
30.1
7.1
9
*
399
Kela drug reimbursment
Venetoclax
20.1
7.1
10
5
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
3.4
7.1
32
95
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
8.0
7.1
15
19
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
3.2
7.1
35
112
L04AA01
ATC
[U] ciclosporin; systemic
3.5
7.0
31
91
F43.29
ICD-10 Finland
Adaptation disorder UNS
4.0
7.0
26
66
Z2221
NOMESCO Finland
Medical doctor
1.4
7.0
374
2857
B34.9
ICD-10 Finland
Viral infection, unspecified
3.2
6.9
34
108
L28
ICPC
Limited function/disability (L)
1.5
6.9
247
1738
J12.8
ICD-10 Finland
Other viral pneumonia
5.5
6.9
19
35
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
2.7
6.9
44
164
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
3.1
6.8
35
115
Z2446
NOMESCO Finland
Social worker
1.9
6.8
90
477
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
6.1
6.8
17
28
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
5.7
6.8
18
32
9761/3-C42.0
ICD-O-3
Waldenstrom macroglobulinemia of blood
40.2
6.8
8
*
R93.7
ICD-10 Finland
Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
16.8
6.7
10
6
J02AC01
ATC
fluconazole; systemic
1.4
6.7
432
3401
1AA09
NOMESCO Finland
NA
22.6
6.7
9
*
B03BA03
ATC
hydroxocobalamin; parenteral
1.8
6.7
102
569
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
3.4
6.6
30
90
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.1
6.6
67
321
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
6.6
464
3704
B01.9
ICD-10 Finland
Varicella without complication
12.3
6.6
11
9
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
2.7
6.5
42
158
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
6.9
6.5
15
22
N08.2*D89.82
ICD-10 Finland
Nepropathy caused by deposition of the light chain of the immunoglobulins
70.1
6.4
7
*
L03AA10
ATC
lenograstim; parenteral
70.1
6.4
7
*
J12.2
ICD-10 Finland
Parainfluenza virus pneumonia
70.1
6.4
7
*
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
7.4
6.4
14
19
TK810
NOMESCO Finland
Hemofiltration
5.2
6.3
18
35
E83.51
ICD-10 Finland
Hypocalcemia
6.0
6.3
16
27
GA6AA
NOMESCO Finland
Sternal X-ray examination
11.1
6.3
11
10
9733/3-C42.1
ICD-O-3
Plasma cell leukemia of bone marrow
+∞
6.3
6
*
E85.0
ICD-10 Finland
Non-neuropathic heredofamilial amyloidosis
+∞
6.3
6
*
C08CA01
ATC
amlodipine; oral
1.3
6.2
569
4719
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
5.0
6.2
18
36
NB3AA
NOMESCO Finland
Clavicle X-ray examination
3.8
6.2
24
64
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.9
6.2
81
430
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.3
6.2
28
85
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
4.2
6.1
21
50
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
6.1
149
959
R04.0
ICD-10 Finland
Epistaxis
1.7
6.1
115
688
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
4.0
6.1
22
55
A04AA02
ATC
granisetron; systemic, transdermal
1.9
6.1
84
454
ZX100
NOMESCO Finland
Oral
3.4
6.0
27
81
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
6.0
588
4916
A98
ICPC
Health maint/preventive medicine
0.7
6.0
1182
12623
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_MULTIPLE_MYELOMA_PLASMA_CELL – Multiple myeloma and malignant plasma cell neoplasms
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).